Page last updated: 2024-09-05

phosphatidylcholines and ambroxol

phosphatidylcholines has been researched along with ambroxol in 22 studies

Compound Research Comparison

Studies
(phosphatidylcholines)
Trials
(phosphatidylcholines)
Recent Studies (post-2010)
(phosphatidylcholines)
Studies
(ambroxol)
Trials
(ambroxol)
Recent Studies (post-2010) (ambroxol)
32,2044435,593714130225

Protein Interaction Comparison

ProteinTaxonomyphosphatidylcholines (IC50)ambroxol (IC50)
Lysosomal acid glucosylceramidaseHomo sapiens (human)4.1
Cytochrome P450 2D6Homo sapiens (human)0.5574
Sodium-dependent serotonin transporterHomo sapiens (human)3.391

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199018 (81.82)18.7374
1990's3 (13.64)18.2507
2000's1 (4.55)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Renovanz, HD; von Seefeld, H1
Kock, HC; Merkus, JM; Roozen, PH; Verhoeven, AG1
Mears, GJ; Taylor, PJ; Van Petten, GR1
Blümel, G; Haas, S; Krieglsteiner, P; Lohninger, A; Wriedt-Lübbe, I1
Dauberschmidt, R; Iwainsky, H; Kuckelt, W; Winsel, K1
Egberts, J; Fontijne, P; Wamsteker, K1
Arakawa, R; Hashimoto, Y; Honda, H; Ikarashi, Y; Noguchi, Y; Uchida, M1
Benazzo, M; Lligona, L; Manzoni, M; Mira, E; Salmona, M; Tacconi, MT1
Jabłonka, S; Ledwozyw, A; Tusińska, E1
Abbà, L; Genghini, M; Knerich, R; Luisetti, M; Pagnoni, AM; Peona, V; Pozzi, E; Salmona, M; Villani, F1
Genghini, M; Luisetti, M; Masturzo, P; Pozzi, E; Salmona, M; Scelsi, M; Spialtini, L1
Cretti, A; Skoczowska, W; Stepińska, J; Zbisławska, P1
Genghini, M; Luisetti, M; Masturzo, P; Pozzi, E; Salmona, M; Spialtini, L1
Müller, B; von Wichert, P; Wilke, A1
Kai, H; Kojima, S; Miyata, T; Nakagawa, M; Okano, Y; Saito, M; Takahama, K1
Engler, H; Szelenyi, I1
Eberhardt, H; von Seefeld, H; Weiss, JM1
Meyer-Ingold, W; Reissmann, H; von Wichert, P; Wiegers, U1
Batenburg, JJ; Oldenborg, V; Post, M; Schuurmans, EA; van der Molen, AJ; van Golde, LM1
Brodecky, V; Maloney, JE1
Wirtz, HR1

Trials

1 trial(s) available for phosphatidylcholines and ambroxol

ArticleYear
Surfactant in the amniotic fluid and bromhexine metabolite VIII.
    European journal of obstetrics, gynecology, and reproductive biology, 1978, Volume: 8, Issue:2

    Topics: Ambroxol; Amniotic Fluid; Bromhexine; Clinical Trials as Topic; Double-Blind Method; Female; Gestational Age; Humans; Isoxsuprine; Obstetric Labor, Premature; Phosphatidylcholines; Pregnancy; Pulmonary Surfactants; Sphingomyelins

1978

Other Studies

21 other study(ies) available for phosphatidylcholines and ambroxol

ArticleYear
[Surfactant and respiratory distress syndrome].
    Praxis und Klinik der Pneumologie, 1978, Volume: 32, Issue:7

    Topics: Adrenergic beta-Agonists; Ambroxol; Amniotic Fluid; Animals; Dexamethasone; Glucocorticoids; Humans; Hyaline Membrane Disease; Infant, Newborn; Infant, Premature; Lung; Phosphatidylcholines; Prenatal Diagnosis; Pulmonary Alveoli; Pulmonary Surfactants; Rabbits; Rats; Respiratory Distress Syndrome, Newborn; Sphingomyelins

1978
The effects of NA872 on pulmonary maturation in the fetal lamb and rabbit.
    American journal of obstetrics and gynecology, 1978, Jan-01, Volume: 130, Issue:1

    Topics: Ambroxol; Animals; Blood Pressure; Body Fluids; Bromhexine; Female; Heart Rate; Lung; Lung Volume Measurements; Maternal-Fetal Exchange; Phosphatidylcholines; Pregnancy; Pressure; Pulmonary Surfactants; Rabbits; Seasons; Sheep; Sphingomyelins; Trachea

1978
[Animal experiments on the effect of various drugs on the lecithin content and fibrinolytic activity of the fetal lung].
    Archives of gynecology, 1979, Jul-20, Volume: 228, Issue:1-4

    Topics: Ambroxol; Animals; Betamethasone; Bromhexine; Carnitine; Female; Lung; Phosphatidylcholines; Pregnancy; Pulmonary Surfactants; Rats

1979
[The lipids of the lungs in experimental aspiration pneumonitis (author's transl)].
    Zeitschrift fur Erkrankungen der Atmungsorgane, 1978, Volume: 151, Issue:2

    Topics: Ambroxol; Animals; Cholesterol; Hydrochloric Acid; Lipids; Lung; Male; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Pneumonia, Aspiration; Sphingomyelins; Swine

1978
Indication of increase of the lecithin/sphingomyelin (L/S) ratio in lung fluid of lambs maternally treated with metabolite VIII of Bisolvon.
    Biology of the neonate, 1976, Volume: 29, Issue:5-6

    Topics: Ambroxol; Animals; Bromhexine; Exudates and Transudates; Female; Fetus; Lung; Maternal-Fetal Exchange; Phosphatidylcholines; Pregnancy; Sheep; Sphingomyelins; Stimulation, Chemical

1976
[Effects of ambroxol HCl on the guinea pig tracheal mucous secretion and the rat pulmonary surfactant secretion].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 100, Issue:4

    Topics: Ambroxol; Animals; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Expectorants; Glycosaminoglycans; Guinea Pigs; Male; Mucus; Phosphatidylcholines; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Trachea

1992
Effect of ambroxol on rabbit eustachian tube surfactant.
    ORL; journal for oto-rhino-laryngology and its related specialties, 1992, Volume: 54, Issue:3

    Topics: Ambroxol; Animals; Eustachian Tube; Female; Lung; Palmitic Acid; Palmitic Acids; Phosphatidylcholines; Phospholipids; Pulmonary Surfactants; Rabbits; Surface-Active Agents

1992
[The effect of ambroxol on peroxidative processes in dog lung mitochondria].
    Polskie archiwum weterynaryjne, 1991, Volume: 31, Issue:3-4

    Topics: Ambroxol; Animals; Dogs; Dose-Response Relationship, Drug; In Vitro Techniques; Lipid Peroxidation; Lung; Malondialdehyde; Mitochondria; Phosphatidylcholines; Phosphatidylethanolamines

1991
Ambroxol and pulmonary toxicity induced by antineoplastic drugs.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:2

    Topics: Ambroxol; Animals; Antineoplastic Agents; Bleomycin; Bromhexine; Busulfan; Cyclophosphamide; Humans; Lung Diseases; Lymphocytes; Macrophages; Methotrexate; Middle Aged; Neutrophils; Nitrosourea Compounds; Phosphatidylcholines; Procarbazine; Pulmonary Alveoli; Pulmonary Fibrosis; Rats; Respiratory Function Tests

1986
Role of alveolar phospholipids in bleomycin-induced pulmonary fibrosis in the rat.
    Respiration; international review of thoracic diseases, 1987, Volume: 51 Suppl 1

    Topics: Ambroxol; Animals; Bleomycin; Macrophages; Male; Membrane Fluidity; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Fibrosis; Rats; Rats, Inbred F344; Superoxides; Therapeutic Irrigation; Viscosity

1987
[Comparison of the effect of Lasolvan and betamethasone on lung maturity of fetal rabbits].
    Zentralblatt fur Gynakologie, 1989, Volume: 111, Issue:6

    Topics: Ambroxol; Animals; Betamethasone; Body Weight; Bromhexine; Female; Fetal Organ Maturity; Infusions, Intravenous; Lung; Organ Size; Phosphatidylcholines; Pregnancy; Rabbits; Sphingomyelins

1989
In vivo studies of rat alveolar macrophage [corrected] microviscosity: influence of pulmonary surfactant synthesis stimulation.
    Lung, 1987, Volume: 165, Issue:6

    Topics: Ambroxol; Animals; Bronchoalveolar Lavage Fluid; Cell Membrane; Macrophage Activation; Macrophages; Male; Pancreatic Elastase; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Superoxides; Viscosity

1987
Ambroxol increases the choline but not fatty acid incorporation into lung phospholipids in experimental lung disorders.
    Respiration; international review of thoracic diseases, 1987, Volume: 52, Issue:2

    Topics: Ambroxol; Animals; Bromhexine; Choline; Fatty Acids; Female; Lung; Lung Diseases; Male; Peritonitis; Phosphatidylcholines; Phospholipids; Pulmonary Surfactants; Rabbits; Rats; Rats, Inbred Strains; Respiratory Distress Syndrome; Sphingomyelins

1987
[Effects of ambroxol on pulmonary surfactant--analysis of the fatty acid composition of phosphatidylcholine in the sputum and normal respiratory tract fluid in rabbits].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 88, Issue:1

    Topics: Ambroxol; Animals; Body Fluids; Bromhexine; Bronchi; Fatty Acids; Lung; Male; Phosphatidylcholines; Pulmonary Surfactants; Rabbits; Sputum

1986
Cytoprotective role of gastric surfactant in the ethanol-produced gastric mucosal injury of the rat.
    Pharmacology, 1986, Volume: 33, Issue:4

    Topics: Aluminum Hydroxide; Ambroxol; Animals; Bromhexine; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Male; Membrane Lipids; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Rats; Rats, Inbred Strains; Surface-Active Agents

1986
Stimulation of lung maturity: investigation of ambroxol in various animal models.
    Acta physiologica Hungarica, 1985, Volume: 65, Issue:3

    Topics: Ambroxol; Animals; Body Fluids; Bromhexine; Cells, Cultured; Fetal Organ Maturity; Lung; Lung Compliance; Phosphatidylcholines; Pulmonary Surfactants; Rabbits; Rats; Respiration; Sheep; Sphingomyelins; Time Factors; Trachea

1985
[Synthesis of water-soluble metabolites of cholin and incorporation of choline in phosphatidylcholine in the lungs of normal and ambroxol-pretreated rabbits].
    Praxis und Klinik der Pneumologie, 1984, Volume: 38, Issue:3

    Topics: Ambroxol; Animals; Bromhexine; Choline; Lung; Phosphatidylcholines; Phosphorylation; Phosphotransferases; Premedication; Rabbits

1984
Hyaline membrane disease: recent developments.
    European journal of obstetrics, gynecology, and reproductive biology, 1983, Volume: 15, Issue:4-6

    Topics: Ambroxol; Amniotic Fluid; Bronchopulmonary Dysplasia; Female; Glucocorticoids; Humans; Hyaline Membrane Disease; Infant, Newborn; Oxygen; Phosphatidylcholines; Positive-Pressure Respiration; Pregnancy; Prenatal Diagnosis; Prognosis; Pulmonary Surfactants; Sphingomyelins

1983
The perfused rat lung as a model for studies on the formation of surfactant and the effect of Ambroxol on this process.
    Lung, 1983, Volume: 161, Issue:6

    Topics: Ambroxol; Animals; Bromhexine; Lung; Male; Models, Biological; Perfusion; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Pulmonary Surfactants; Rats; Rats, Inbred Strains

1983
Influence of the compound NA872 on cardiopulmonary maturation in the unanaesthetised fetal lamb.
    Biology of the neonate, 1980, Volume: 37, Issue:5-6

    Topics: Ambroxol; Amniotic Fluid; Animals; Blood Pressure; Bromhexine; Female; Fetal Heart; Fetus; Lung; Phosphatidylcholines; Pregnancy; Sheep; Sphingomyelins; Venous Pressure

1980
[Effect of ambroxol on surfactant secretion and synthesis in isolated type II alveolar cells].
    Pneumologie (Stuttgart, Germany), 2000, Volume: 54, Issue:7

    Topics: Ambroxol; Animals; Cells, Cultured; Choline; Male; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley

2000