Page last updated: 2024-09-05

phosphatidylcholines and acetaminophen

phosphatidylcholines has been researched along with acetaminophen in 13 studies

Compound Research Comparison

Studies (phosphatidylcholines)	Trials (phosphatidylcholines)	Recent Studies (post-2010) (phosphatidylcholines)	Studies (acetaminophen)	Trials (acetaminophen)	Recent Studies (post-2010) (acetaminophen)
32,204	443	5,593	20,696	2,848	8,242

Protein Interaction Comparison

Protein	Taxonomy	phosphatidylcholines (IC50)	acetaminophen (IC50)
Myoglobin	Homo sapiens (human)		2.3

Research

Studies (13)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (23.08)	18.7374
1990's	2 (15.38)	18.2507
2000's	2 (15.38)	29.6817
2010's	2 (15.38)	24.3611
2020's	4 (30.77)	2.80

Authors

Authors	Studies
Conti, M; Magistretti, MJ; Malandrino, S	1
Wendel, A; Werner, C	1
Jaeschke, H; Wendel, A; Werner, C	1
Clemens, M; Gerlach, U; Lessing, U; Lohmann, J; Schriewer, H	1
Horning, MG; Hughes, H; Lauterburg, BH; Mitchell, JR; Smith, CV	1
Duruz, H; Liguori, V; Mahler, F; Mahler, P; Mautone, G; Ramazzina, M	1
Chiji, H; Fukushima, M; Han, KH; Lee, CH; Nakano, M; Ohba, K; Sekikawa, M; Shimada, K	1
Dygai, AM; Udut, VV; Vengerovsky, AI	1
Li, CM; Li, XB; Liu, XL; Ma, SC; Mao, YM; Ming, YN; Wang, XL; Wang, ZY; Zhang, JY	1
Jagmag, T; Jose, SP; Kulkarni, A; Mohanan, R; Sreevallabhan, S; Sukumaran, S; Tilwani, J	1
Bleuel, M; De Mel, JU; Gupta, S; Harmon, S; Roth, EW; Schneider, GJ; Siebenbuerger, M; Stingaciu, L	1
Bamba, T; Izumi, Y; Matsuoka, Y; Nishida, M; Nishiyama, K; Suematsu, M; Sugiura, Y; Takahashi, M; Yamada, KI	1
Ali, RO; Aucoin, AV; Dalier, A; Dikkumbura, AS; Gilbert, DW; Haber, LH; Schneider, GJ	1

Trials

1 trial(s) available for phosphatidylcholines and acetaminophen

Article	Year
Double-blind, randomized, controlled study on the efficacy and safety of a novel diclofenac epolamine gel formulated with lecithin for the treatment of sprains, strains and contusions. Drugs under experimental and clinical research, 2003, Volume: 29, Issue:1 Topics: Acetaminophen; Administration, Topical; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Ankle Injuries; Anti-Inflammatory Agents; Contusions; Diclofenac; Double-Blind Method; Female; Gels; Humans; Knee Injuries; Leg Injuries; Male; Middle Aged; Pain Measurement; Phosphatidylcholines; Prospective Studies; Sprains and Strains	2003

Article

Year

Double-blind, randomized, controlled study on the efficacy and safety of a novel diclofenac epolamine gel formulated with lecithin for the treatment of sprains, strains and contusions.

Drugs under experimental and clinical research, 2003, Volume: 29, Issue:1

Topics: Acetaminophen; Administration, Topical; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Ankle Injuries; Anti-Inflammatory Agents; Contusions; Diclofenac; Double-Blind Method; Female; Gels; Humans; Knee Injuries; Leg Injuries; Male; Middle Aged; Pain Measurement; Phosphatidylcholines; Prospective Studies; Sprains and Strains

2003

Other Studies

12 other study(ies) available for phosphatidylcholines and acetaminophen

Article	Year
Protective activity of silipide on liver damage in rodents. Japanese journal of pharmacology, 1992, Volume: 60, Issue:4 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Ethanol; Female; Galactosamine; Male; Phosphatidylcholines; Praseodymium; Rats; Rats, Sprague-Dawley; Rats, Wistar; Silymarin	1992
Hepatic uptake and antihepatotoxic properties of vitamin E and liposomes in the mouse. Chemico-biological interactions, 1990, Volume: 75, Issue:1 Topics: Acetaminophen; Animals; Benzo(a)pyrene; Chemical and Drug Induced Liver Injury; Drug Carriers; Galactosamine; Lipopolysaccharides; Liposomes; Liver; Male; Mice; Phosphatidylcholines; Vitamin E	1990
Disposition and hepatoprotection by phosphatidyl choline liposomes in mouse liver. Chemico-biological interactions, 1987, Volume: 64, Issue:1-2 Topics: Acetaminophen; Animals; Fatty Acids; Glutathione; Lipid Peroxides; Liposomes; Liver; Male; Mice; Phosphatidylcholines	1987
The influence of paracetamol on the hepatic biosynthesis of lecithin. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1984, Volume: 7 Topics: Acetaminophen; Humans; In Vitro Techniques; Liver; Phosphatidylcholines	1984
Overview of alkylation and peroxidation mechanisms in acute lethal hepatocellular injury by chemically reactive metabolites. Seminars in liver disease, 1981, Volume: 1, Issue:2 Topics: Acetaminophen; Alkylation; Animals; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Ethane; Glutathione; Liver; Liver Diseases; Male; Mice; Pentanes; Peroxides; Pharmaceutical Preparations; Phosphatidylcholines	1981
Hepatoprotective effects of the water extract from adzuki bean hulls on acetaminophen-induced damage in rat liver. Journal of nutritional science and vitaminology, 2004, Volume: 50, Issue:5 Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Fabaceae; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Liver; Liver Diseases; Male; Phosphatidylcholines; Phosphatidylethanolamines; Plant Extracts; Rats; Rats, Inbred F344; Water	2004
Effects of phospholipid hepatoprotectors on apoptosis during experimental liver pathology induced by isoniazid and paracetamol. Bulletin of experimental biology and medicine, 2013, Volume: 154, Issue:5 Topics: Acetaminophen; Alkaline Phosphatase; Animals; Apoptosis; Bilirubin; Carotenoids; Chemical and Drug Induced Liver Injury; Drug Combinations; Granulocytes; Interleukin-10; Isoniazid; Liver Function Tests; Lymphocytes; Male; Phosphatidylcholines; Phospholipids; Rats; Succinic Acid; Transaminases; Tumor Necrosis Factor-alpha	2013
Liquid chromatography mass spectrometry-based profiling of phosphatidylcholine and phosphatidylethanolamine in the plasma and liver of acetaminophen-induced liver injured mice. Lipids in health and disease, 2017, Aug-14, Volume: 16, Issue:1 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Choline Kinase; Chromatography, Liquid; Gene Expression Regulation; Hepatocytes; Injections, Intraperitoneal; Liver; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phospholipases	2017
Hepatoprotective effect of essential phospholipids enriched with virgin coconut oil (Phoscoliv) on paracetamol-induced liver toxicity. Journal of food biochemistry, 2021, Volume: 45, Issue:2 Topics: Acetaminophen; Animals; Coconut Oil; Liver; Oxidative Stress; Phosphatidylcholines; Rats; Rats, Wistar	2021
Acetaminophen Interactions with Phospholipid Vesicles Induced Changes in Morphology and Lipid Dynamics. Langmuir : the ACS journal of surfaces and colloids, 2021, 08-10, Volume: 37, Issue:31 Topics: Acetaminophen; Lipid Bilayers; Phosphatidylcholines; Phospholipids; Scattering, Small Angle; X-Ray Diffraction	2021
Structural library and visualization of endogenously oxidized phosphatidylcholines using mass spectrometry-based techniques. Nature communications, 2021, 11-03, Volume: 12, Issue:1 Topics: Acetaminophen; Animals; Cytochrome P-450 CYP2E1; Fatty Acids, Unsaturated; Glutathione; Lipidomics; Liver; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Molecular Imaging; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; RAW 264.7 Cells; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2021
Influence of Acetaminophen on Molecular Adsorption and Transport Properties at Colloidal Liposome Surfaces Studied by Second Harmonic Generation Spectroscopy. Langmuir : the ACS journal of surfaces and colloids, 2022, 03-29, Volume: 38, Issue:12 Topics: Acetaminophen; Adsorption; Lipid Bilayers; Liposomes; Phosphatidylcholines; Second Harmonic Generation Microscopy; Spectrum Analysis	2022