phosphatidylcholines has been researched along with 1-palmitoyl-2-oleoylphosphatidylcholine in 1950 studies
| Studies (phosphatidylcholines) | Trials (phosphatidylcholines) | Recent Studies (post-2010) (phosphatidylcholines) | Studies (1-palmitoyl-2-oleoylphosphatidylcholine) | Trials (1-palmitoyl-2-oleoylphosphatidylcholine) | Recent Studies (post-2010) (1-palmitoyl-2-oleoylphosphatidylcholine) |
|---|---|---|---|---|---|
| 7 | 0 | 2 | 1,978 | 3 | 932 |
| 101 | 1 | 21 | 1,978 | 3 | 932 |
| 32,204 | 443 | 5,593 | 1,978 | 3 | 932 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 67 (3.44) | 18.7374 |
| 1990's | 268 (13.74) | 18.2507 |
| 2000's | 594 (30.46) | 29.6817 |
| 2010's | 931 (47.74) | 24.3611 |
| 2020's | 90 (4.62) | 2.80 |
| Authors | Studies |
|---|---|
| Feigenson, GW; Konyakhina, TM | 1 |
| Derreumaux, P; Lu, Y; Nguyen, PH; Salsbury, FR; Shi, XF; Sterpone, F | 1 |
| Brockman, HL; Cunningham, BA; Tsujita, T | 1 |
| Jaworsky, M; Mendelsohn, R | 1 |
| Brockman, HL; Muderhwa, JM; Smaby, JM | 1 |
| Bienvenüe, A; Hoekstra, D; Pécheur, EI; Sainte-Marie, J | 1 |
| Arnhold, J; Osipov, AN; Panasenko, OM; Schiller, J; Spalteholz, H | 1 |
| Epand, RF; Epand, RM; Sayer, BG | 2 |
| Goto, M; Kaneshina, S; Matsuki, H; Miyazaki, E; Tada, K; Tamai, N | 1 |
| Feigenson, GW; Goh, SL; Heberle, FA; Petruzielo, RS; Wu, J | 1 |
| Conboy, JC; Smith, KA | 1 |
| Wydro, P | 1 |
| Evans, E; Rawicz, W; Smith, BA | 1 |
| Li, GH | 1 |
| Capponi, S; Freites, JA; Tobias, DJ; White, SH | 1 |
| Hubbell, WL; Shin, YK | 1 |
| Bryant, G; Pope, JM; Wolfe, J | 1 |
| Seelig, A | 2 |
| Fèvre, F; Henry, JP; Neyton, J; Pelleschi, M; Thieffry, M | 1 |
| Ho, C; Stubbs, CD | 1 |
| Eklund, KK; Kasurinen, J; Kinnunen, PK; Somerharju, PJ; Virtanen, JA | 1 |
| Beschiaschvili, G; Seelig, J | 2 |
| Popescu, T; Schwarz, G; Zong, RT | 1 |
| Okuda, H; Tsujita, T | 1 |
| Brown, RE; Hyland, KJ | 1 |
| Schumaker, MF | 1 |
| Butko, P; Cheng, KH | 1 |
| Carrier, D; Jarrell, HC; Mingeot-Leclercq, MP; Schanck, A; Smith, IC; Tulkens, PM | 1 |
| Brockman, HL; Muderhwa, JM | 3 |
| Lund-Katz, S; Phillips, MC; Sparks, DL | 1 |
| Cafiso, DS; Ellena, JF; Lepore, LS | 1 |
| Kibelbek, J; Litman, BJ; Mitchell, DC | 1 |
| Slotte, JP | 1 |
| Ho, C; Stubbs, CD; Williams, BW | 1 |
| Silvius, JR | 1 |
| Nichols, JW; Shoemaker, DG | 1 |
| Butko, P; Hapala, I; Nemecz, G; Schroeder, F | 1 |
| Ashton, MR; Hall, MA; Kelly, FJ; Normand, IC; Postle, AD; Smith, SL | 1 |
| Ashton, MR; Austin, NC; Hall, MA; Normand, IC; Postle, AD; Smith, DE | 1 |
| Bloom, M; Nezil, FA | 1 |
| Bayerl, S; Bloom, M; Nezil, FA | 1 |
| Hiskey, RG; Pearce, KH; Thompson, NL | 1 |
| Budil, DE; Ewert, U; Freed, JH; Shin, YK | 1 |
| Cassal, JM; Habiger, RG; Kempen, HJ; Seelig, J | 1 |
| Macdonald, PM; Rydall, JR | 1 |
| Käs, J; Sackmann, E | 1 |
| Frey, S; Tamm, LK | 2 |
| Carleton, JN; Lentz, BR; Sorrentino, AM; Wu, JR | 1 |
| Bechinger, B; Seelig, J | 1 |
| Borgström, B; Lindström, MB; Persson, J; Thurn, L | 1 |
| Finlayson-Pitts, BJ; Lai, CC | 1 |
| Bloom, M; Roux, M | 2 |
| Baeuerle, HD; Beschiaschvili, G | 1 |
| Ali, S; Brockman, HL; Brown, RE | 1 |
| Cabiaux, V; De Meutter, J; Goormaghtigh, E; Parente, RA; Ruysschaert, JM; Szoka, F | 1 |
| Balgavy, P; Hermetter, A; Laggner, P; Lohner, K; Paltauf, F | 1 |
| Hui, SW; Isac, TV; Sen, A | 1 |
| Bloom, M; Cullis, PR; Lafleur, M | 1 |
| Gardam, MA; Silvius, JR | 1 |
| Chapman, CJ; Erdahl, WL; Pfeiffer, DR; Taylor, RW | 3 |
| Hermetter, A; Loidl, J; Paltauf, F | 1 |
| Jonas, A; Kézdy, KE; Krul, ES; Toohill, KL; Wald, JH | 1 |
| Freed, JH; Moscicki, JK; Shin, YK | 1 |
| Hyslop, PA; Morel, B; Sauerheber, RD | 1 |
| Bartoldus, I; Tamm, LK | 1 |
| Elder, MG; Helmig, R; Lumb, MR; Roseblade, CK; Sullivan, MH; Uldbjerg, N | 1 |
| Butko, P; Nemecz, G; Scallen, TJ; Schroeder, F | 1 |
| Jones, JD; Thompson, TE | 2 |
| Nichols, JW; Ozarowski, J | 1 |
| Miller, C | 1 |
| Macdonald, PM; Seelig, A | 1 |
| Duclohier, H; Molle, G; Spach, G | 1 |
| Freed, JH; Shin, YK | 2 |
| Feigenson, GW | 1 |
| Blanche, PJ; Forte, TM; Gong, EL; Nichols, AV; Shore, VG; Weisgraber, KH | 1 |
| Bloom, M; Cullis, PR; Fine, B; Lafleur, M; Sternin, E | 1 |
| Hermetter, A; Kalb, E; Paltauf, F | 1 |
| Chan, L; Gotto, AM; Kim, TW; Knapp, RD; Pao, Q; Pownall, HJ; Yang, CY | 1 |
| Jobe, A; Lewis, J | 1 |
| Baumann, WJ; Kumar, VV; Malewicz, B | 1 |
| Bar, LK; Barenholz, Y; Chong, PL; Thompson, TE | 1 |
| Cutsforth, GA; Hermans, J; Lentz, BR; Whitaker, RN | 1 |
| Schwyzer, R | 1 |
| Feix, JB; Girotti, AW; Kalyanaraman, B; Sieber, F; Thomas, JP | 1 |
| Adar, L; Davis, PJ; Gross, Z; Ne'eman, Z; Rottem, S | 1 |
| Jonas, A; Kézdy, KE; Trick, WE; Zorich, NL | 1 |
| Blanche, PJ; Forte, TM; Gong, EL; Nichols, AV; Shore, VG | 1 |
| Bottega, R; Epand, RM | 1 |
| Macdonald, PM; Seelig, J | 3 |
| Nemecz, G; Schroeder, F | 1 |
| Barenholz, Y; Gratton, E; Nemecz, G; Schroeder, F; Thompson, TE | 1 |
| Allegrini, PR; Seelig, A; Seelig, J | 1 |
| Bechinger, B; Macdonald, PM; Seelig, J | 1 |
| Fontaine, RN; Nemecz, G; Schroeder, F | 1 |
| Erne, D; Schwyzer, R | 1 |
| Brauner, JW; Mendelsohn, R; Prendergast, FG | 1 |
| Chang, CC; Kihara, H; Nakamura, H; Oda, N; Ohno, M; Sakai, H; Sakamoto, S; Shieh, TC | 1 |
| Brockman, HL; Smaby, JM | 2 |
| Brockman, HL; Massey, JB; Pao, Q; Pownall, HJ | 1 |
| Barenholz, Y; Gratton, E; Schroeder, F; Thompson, TE | 1 |
| Flatmark, T; Husebye, ES | 1 |
| Brown, RE; Thompson, TE | 1 |
| Bar, LK; Barenholz, Y; Thompson, TE | 2 |
| James, DR; Petersen, NO; Turnbull, JR; Wagner, BD; Ware, WR | 1 |
| Gotto, AM; Hester, L; Ponsin, G; Pownall, HJ; Sparrow, JT | 1 |
| Curatolo, W | 1 |
| Curatolo, W; Neuringer, LJ | 1 |
| Deamer, DW; Shew, RL | 1 |
| Clegg, RM; De Rosa, M; Gambacorta, A; Hallmann, D; Vaz, WL | 1 |
| Forster, S; Ilderton, E; Norris, JF; Summerly, R; Yardley, HJ | 1 |
| Chong, PL; Thompson, TE; van der Meer, BW | 1 |
| Benson, DM; Plant, AL; Smith, LC | 1 |
| Chiarugi, V; Ruggiero, M; Vannucchi, S | 1 |
| Everett, J; Holloway, PW; Markello, T; Tennyson, J; Zlotnick, A | 1 |
| Curatolo, W; Neuringer, LJ; Sears, B | 1 |
| Bonney, RC | 1 |
| Greenhut, SF; Roseman, MA | 1 |
| Seelig, J; Tamm, LK | 1 |
| Fringeli, UP; Gremlich, HU; Schwyzer, R | 1 |
| Hughes, BL; Resseguie, WD | 1 |
| Altenbach, C; Seelig, J | 1 |
| Boheim, G; Hanke, W; Jung, G; Katz, E; Methfessel, C; Wilmsen, HU | 1 |
| Boni, LT; Hui, SW | 1 |
| Curatolo, W; Manstein, JL; Sears, B; Stark, RE | 1 |
| Plant, AL; Pownall, HJ; Smith, LC | 1 |
| Guilleme, J; Ribera, A; Rico, M; Santaren, JF | 1 |
| Lavialle, F; Levin, IW | 1 |
| Bally, MB; Choice, E; Madden, TD; Masin, D; Meloche, M | 1 |
| Anderson, GJ; Anyan, WR; Hall, SB; Kahn, MC | 1 |
| Bergeron, J; Castro, G; Frank, PG; Marcel, YL; Meng, QH; Scales, D | 1 |
| Bloom, M; Monck, M; Nezil, FA; Roux, M | 1 |
| Ho, C; Kelly, MB; Rubin, E; Slater, SJ; Stubbs, CD; Taddeo, FJ | 1 |
| Brasseur, R; Castro, GR; Clavey, V; Denefle, P; Duchateau, P; Fruchart, JC; Luchoomun, J; Rosseneu, M; Theret, N | 1 |
| Budil, DE; Earle, KA; Freed, JH; Ge, M; Moscicki, JK | 1 |
| Dibble, AR; Feigenson, GW | 1 |
| Rabenstein, M; Shin, YK | 1 |
| Burke, JR; Gregor, KR; Lahiri, J; Micanovic, R; Tramposch, KM; Tredup, J; Villafranca, JJ; Witmer, MR | 1 |
| Davidson, WS; Lund-Katz, S; Phillips, MC; Sparks, DL | 1 |
| Pampel, A; Volke, F | 1 |
| Lau, B; Macdonald, PM | 1 |
| Carey, MC; Donovan, JM; Fahey, DA | 1 |
| Calabresi, L; Castro, GR; Marcel, YL; Meng, QH | 1 |
| Barnickel, G; Greiner, HE; Harting, J; Hölzemann, G; Seelig, A | 1 |
| Jones, LR; Reddy, LG; Stokes, DL; Tamm, LK; Tatulian, SA | 1 |
| Hallett, FR; Merrill, AR; Palmer, LR; Strawbridge, KB | 1 |
| Grant, CW; Morrow, MR; Singh, D | 1 |
| Benachir, T; Lafleur, M | 2 |
| Brochon, JC; Reyes Mateo, C; Ulises Acuña, A | 1 |
| Anderson, WH; Brown, RE; Kulkarni, VS | 1 |
| Franková, R; Sikurová, L | 1 |
| Love, WG; Rensen, PC; Taylor, PW | 1 |
| de Fouw, NJ; Op den Kamp, JA; Roelofsen, B; van Deenen, LL; van den Boom, MA; Wassink, MG; Westerman, J | 1 |
| Ben-Shaul, A; Fattal, DR | 1 |
| Huang, Z; Pearce, KH; Thompson, NL | 1 |
| Cheng, KH; Somerharju, P; Sugar, I | 1 |
| Selsted, ME; White, SH; Wimley, WC | 1 |
| Jähnig, F; Rodionova, NA; Surrey, T; Tamm, LK; Tatulian, SA | 1 |
| Eisenblätter, S; Klose, G; Volke, F | 1 |
| Anantharamaiah, GM; Phillips, MC; Segrest, JP; Sparks, DL | 1 |
| Blackshear, PJ; Johnson, JD; Kim, J; McLaughlin, S | 1 |
| Litman, BJ; Mitchell, DC | 1 |
| Merrill, AR; Rasper, DM | 1 |
| Shin, YK; Thorgeirsson, TE; Yu, YG | 1 |
| Ashton, MR; Hall, MA; Postle, AD; Smith, DE | 1 |
| Gryczynski, I; Johnson, ML; Laczko, G; Lakowicz, JR; Wiczk, W | 1 |
| Cheng, KH | 1 |
| van den Berg, J; Winterbourn, C | 1 |
| Creutz, CE; Gilmanshin, R; Tamm, LK | 1 |
| Eisenblätter, S; Galle, J; Klose, G; Volke, F | 1 |
| Bryant, G; Koster, KL; Lynch, DV; Webb, MS | 1 |
| Kuipers, ME; Love, WG; Rensen, PC; Taylor, PW; Versluis, AJ | 1 |
| Crepeau, RH; Freed, JH; Lee, S; Patyal, B; Saxena, S | 1 |
| Budil, DE; Freed, JH; Ge, M | 1 |
| Pryor, WA; Salgo, MG; Squadrito, GL | 1 |
| Huang, C; Li, S; Lin, HN; Wang, ZQ | 1 |
| Cullis, PR; Madden, TD; Mui, BL; Pritchard, PH | 1 |
| Joiner, CH; Kavecansky, J; Schroeder, F | 1 |
| Hinton, DP; Johnson, CS | 1 |
| Feix, JB; Hyde, JS; Mchaourab, HS | 1 |
| Harvey, SC; Pearce, LL | 1 |
| Charpigny, G; Martal, J; Reinaud, P; Tamby, JP | 1 |
| Brochon, JC; Pilar Lillo, M; Reyes Mateo, C; Ulises Acuña, A | 1 |
| Brochon, JC; Reyes Mateo, C; Tauc, P | 1 |
| Cullis, PR; Fenske, DB | 1 |
| Ramsden, JJ | 1 |
| Dalton, MB; Swaney, JB | 1 |
| Macdonald, PM; Marassi, FM; Shivers, RR | 1 |
| Epand, RM; Jeffrey, KR; Katsaras, J; Yang, DS | 1 |
| Degovics, G; Gnamusch, E; Laggner, P; Lohner, K; Paltauf, F | 1 |
| Djukic, S; Macdonald, PM; Marassi, FM | 1 |
| Seelig, J; Thomas, PG | 1 |
| Scarlata, S; Teng, Q | 1 |
| White, SH; Wimley, WC | 1 |
| Grant, CW; Morrow, MR; Singh, DM | 1 |
| Arnhold, J; Arnold, K; Panasenko, OM; Schiller, J | 1 |
| He, K; Huang, H; Ludtke, S | 1 |
| Feng, SS; MacDonald, RC | 1 |
| Cueto, R; Pryor, WA; Salgo, MG | 1 |
| Jähnig, F; Kiefer, H; Nollert, P | 1 |
| Jonas, A; Jonas, J; Lee, BS; Mabry, SA | 1 |
| Eisenhawer, M; Kuhn, A; Soekarjo, M; Vogel, H | 1 |
| Bugaut, M; Gagniarre, J; Gresti, J | 1 |
| Heyse, S; Sänger, M; Sigrist, H; Vogel, H | 1 |
| Baumgartner, W; Gruber, HJ; Schindler, H; Schmidt, T; Schütz, GJ | 1 |
| Roseman, MA; Taylor, KM | 1 |
| Cho, W; Lee, BI; Yoon, ET | 1 |
| Rex, S | 1 |
| Bloom, M; Cullis, PR; Eikenberry, EF; Gruner, SM; Han, Y; Lafleur, M | 1 |
| Bhattacharya, S; Haldar, S | 1 |
| Alt, T; Gerisch, G; Hanakam, F; Lotz, S; Seelig, A | 1 |
| Chung, LA; Thompson, TE | 1 |
| Hajos, F; Krieglsteiner, HP; Lohninger, A; Marz, R; Stangl, H | 1 |
| Angelova, MI; Luisi, PL; Walde, P; Wick, R | 1 |
| Marcel, YL; Sparks, DL; Zhao, Y | 1 |
| Dorovska-Taran, V; Walde, P; Wick, R | 1 |
| Barber, KR; Grant, CW; Rigby, AC; Shaw, GS | 1 |
| Lentz, BR; Wu, H; Zheng, L | 1 |
| Sevanian, A; ter Braake, P; Teunissen, J; van Ginkel, G; Verhagen, JC | 1 |
| Ben-Tal, N; Denisov, G; Honig, B; McLaughlin, S; Peitzsch, RM | 1 |
| Curtis, BA; Laver, DR | 1 |
| Subczynski, WK; Yin, JJ | 1 |
| Chen, SY; Cheng, KH | 1 |
| Acuña, AU; Amat-Guerri, F; Mateo, CR; Souto, AA | 1 |
| Barber, KR; Grant, CW; Rigby, AC | 1 |
| Davidson, WS; Gillotte, KL; Lund-Katz, S; Murley, YM; Yon, E | 1 |
| Nicol, F; Nir, S; Szoka, FC | 2 |
| Macdonald, PM; Mitrakos, P | 5 |
| Anantharamaiah, GM; Brouillette, CG; Engler, JA; Lund-Katz, S; Mishra, VK; Phillips, MC; Ray, MJ; Roberts, L; Rogers, DP; Tendian, SW | 1 |
| Boggs, JM; Cajal, Y; Jain, MK | 1 |
| Alt, T; Seelig, A; Seelig, J; Wenk, MR | 1 |
| Ladokhin, AS; Selsted, ME; White, SH | 1 |
| Bailey, AL; Cullis, PR; Monck, MA | 1 |
| Cajal, Y; Jain, MK | 1 |
| Bernardi, E; Brachais, L; Cosette, P; Duclohier, H | 1 |
| Bernsdorff, C; Gratton, E; Winter, R; Wolf, A | 1 |
| Ghoshroy, KB; Sampson, NS; Zhu, W | 1 |
| Davis, PJ; Keough, KM; Nag, K; Worthman, LA | 1 |
| Castellino, FJ; Ellison, EH | 2 |
| Mason, PE; Mason, RP; Walter, MF | 1 |
| Gray, C; Tamm, LK; Tatulian, SA; Wharton, SA | 1 |
| Cabral-Lilly, DJ; Dank, EH; Dause, RB; Franklin, JC; Janoff, AS; Li, X; Mayhew, E; Perkins, WR; Zha, Y | 1 |
| Schindler, H; Schmidt, T; Schütz, GJ | 1 |
| el Bayâ, A; Galla, HJ; Janshoff, A; Schmidt, MA; Sieber, M; Steinem, C | 1 |
| Andersen, OS; Girshman, J; Greathouse, DV; Koeppe, RE | 1 |
| Beyermann, M; Bienert, M; Dathe, M; Epand, RM; Krause, E; MacDonald, DL; Maloy, WL; Wieprecht, T | 1 |
| Cheng, KH; Ruonala, M; Somerharju, P; Virtanen, J | 1 |
| Luisi, P; Monnard, PA; Oberholzer, T | 1 |
| Jonas, A; Li, Z; Phillips, JC; Schulten, K; Wriggers, W | 1 |
| Seelig, J; Wenk, MR | 1 |
| Bryant, RG; Cafiso, DS; Hodges, MW; Lester, CC; Polnaszek, CF | 1 |
| Hruby, VJ; Lipkowski, AW; Misicka, A; O'Brien, DF; Ramaswami, V; Romanowski, M; Zhu, X | 1 |
| Anantharamaiah, GM; Gazzara, JA; Lund-Katz, S; Palgunachari, MN; Phillips, MC; Segrest, JP; Snow, JW | 1 |
| Anantharamaiah, GM; Gazzara, JA; Lund-Katz, S; Palgunachari, MN; Phillips, MC; Rodrigueza, WV; Segrest, JP; Snow, JW | 1 |
| Huber, R; Kakorin, S; Liemann, S; Neumann, E; Tönsing, K | 1 |
| Albrizio, M; Luisi, PL; Oberholzer, T | 1 |
| Coffill, CR; Hutt, DM; Ramsamy, TA; Schultz, JR; Sparks, DL | 1 |
| Hölzemann, G; Seelig, J; Terzi, E | 1 |
| Rex, S; Schwarz, G | 1 |
| Hodges, RS; Hyde, JS; Kusumi, A; Lewis, RN; McElhaney, RN; Subczynski, WK | 1 |
| de la Llera-Moya, M; Ji, Y; Jian, B; Phillips, MC; Rothblat, GH; Swaney, JB; Tall, AR; Wang, N | 1 |
| Brenner, RR; Córsico, B; Garda, HA; Toledo, JD; Tricerri, A | 1 |
| Crowe, JH; Crowe, LM; Hincha, DK; Oliver, AE | 1 |
| Chauhan, V; Milne, RW; Ramsamy, T; Sparks, DL; Wang, X | 1 |
| Massey, JB; Pownall, HJ | 1 |
| Brochon, JC; Mateo, CR; Tauc, P | 1 |
| Clayton, DF; Davidson, WS; George, JM; Jonas, A | 1 |
| Asaoka, Y; Hullin, F; Kikkawa, U; Nakamura, S; Tsujishita, Y; Yoshida, H; Yoshida, K | 1 |
| Csúcs, G; Ramsden, JJ | 1 |
| Grau, A; Ortiz, A | 1 |
| Barber, KR; Grant, CW; Jones, DH | 1 |
| Akashi, K; Itoh, H; Kinosita, K; Miyata, H | 1 |
| Barranger-Mathys, M; Cafiso, DS; Ellena, JF; Franklin, C; Jayasinghe, S | 1 |
| Friedman, M; Kafoury, RM; Pryor, WA; Salgo, MG; Squadrito, GL; Zou, X | 2 |
| Adeyeye, SO; Anantharamaiah, GM; Datta, G; Lund-Katz, S; Mishra, VK; Palgunachari, MN; Phillips, MC; Segrest, JP | 1 |
| Armen, RS; Feller, SE; Uitto, OD | 1 |
| Sharma, V; Stebe, KJ; Troiano, GC; Tung, L | 1 |
| Bakowsky, U; Bendas, G; Hummel, G; Kettmann, U; Rothe, U; Schmidt, RR; Vogel, J | 1 |
| Hartsel, SC; Mikulecky, P; Ruckwardt, T; Scott, A; Scott, J | 1 |
| Laggner, P; Pabst, G; Pressl, K; Rappolt, M | 1 |
| Epand, RM; Giorgione, JR; Kraayenhof, R | 1 |
| Kuboi, R; Shimanouchi, T; Umakoshi, H | 1 |
| Binder, H; Fritzsche, H; Pohle, W; Selle, C | 1 |
| Pohle, W; Selle, C | 1 |
| Chong, PL; Sugar, IP; Wang, MM | 1 |
| Arnold, W; Moreno, B; Oldfield, E; Orlean, P; Taron, CH; Urbina, JA | 1 |
| Aranda, FJ; Gómez-Fernández, JC; Jiménez-Monreal, AM; Villalaín, J | 1 |
| Ahn, T; Guengerich, FP; Yun, CH | 1 |
| Cho, W; Lichtenbergova, L; Yoon, ET | 1 |
| Gawrisch, K; White, SH; Wimley, WC; Yau, WM | 1 |
| Katsaras, J | 1 |
| Bolard, J; Heywang, C; Masson, CM; Saint-Pierre Chazalet, M | 1 |
| Barber, KR; Grant, CW; Jones, DH; VanDerLoo, EW | 1 |
| Nandel, FS | 1 |
| Massey, JB | 1 |
| Holopainen, JM; Kinnunen, PK; Subramanian, M | 1 |
| Berendsen, HJ; Sansom, MS; Tieleman, DP | 3 |
| Epand, RM; Hughes, DW; Sayer, BG; Stark, RE; Zhou, Z | 1 |
| Amato, I; Lustig, A; Meyer, E; Monnard, PA; Oberholzer, T | 1 |
| Russell, CJ; Shin, YK; Thorgeirsson, TE | 1 |
| Corbalán-García, S; Gómez-Fernández, JC; Micol, V; Sánchez-Piñera, P | 1 |
| Harvey, SC; Sheldahl, C | 1 |
| Braschi, S; Neville, TA; Sparks, DL; Vohl, MC | 1 |
| Marzetta, B; Walde, P | 1 |
| Binder, H; Epand, RM; Heerklotz, HH | 1 |
| Raphael, RM; Stebe, KJ; Troiano, GC; Tung, L | 1 |
| Schwarz, G; Taylor, SE | 1 |
| Song, X; Swanson, BI | 1 |
| El Jastimi, R; Lafleur, M | 1 |
| Alt, T; Heck, M; Hofmann, KP; Pellaud, J; Seelig, A; Seitz, HR | 1 |
| Luisi, PL; Nierhaus, KH; Oberholzer, T | 1 |
| Beyermann, M; Seelig, J; Wieprecht, T | 1 |
| Arbuzova, A; Schwarz, G | 1 |
| Ito, S; Kuwabata, S; Nakaminami, T; Yoneyama, H | 1 |
| Hofmann, KP; Maretzki, D; Meyboom, A; Stevens, PA | 1 |
| Gear, AR; Holloway, PW; Simon, CG | 1 |
| Forrest, LR; Randa, HS; Sansom, MS; Voth, GA | 1 |
| Chiu, SW; Jakobsson, E; Scott, HL; Subramaniam, S | 1 |
| Heuck, AP; Johnson, AE; Parker, MW; Rossjohn, J; Shatursky, O; Shepard, LA; Tweten, RK | 1 |
| Başaran, N; Doebler, RW; Goldston, H; Holloway, PW | 1 |
| Ball, JM; Billheimer, JT; Huang, H; Schroeder, F | 1 |
| Cornell, RB; Drobnies, AE; Thewalt, JL; van Der Ende, B | 1 |
| Roberts, MF; Seaton, B; Stieglitz, K | 1 |
| Ladokhin, AS | 1 |
| Cafiso, DS; Gorzelle, BM; Lonzer, WL; Nagy, JK; Oxenoid, K; Sanders, CR | 1 |
| Durbin, DM; Jonas, A | 1 |
| Capener, CE; Forrest, LR; Sansom, MS; Shrivastava, IH | 1 |
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| Ausili, A; Gómez-Fernández, JC; Rodríguez-González, I; Teruel, JA; Torrecillas, A | 1 |
| Holló, G; Lagzi, I; Miele, Y; Rossi, F | 1 |
| Bamert, RS; Chen, X; Ding, Y; Duff, AP; Hsu, HY; Le Brun, AP; Lithgow, T; Shen, HH; Shiota, T; Wu, CM | 1 |
| De Zotti, M; Dzuba, SA; Formaggio, F; Gobbo, M; Sannikova, NE; Syryamina, VN | 1 |
| Enoki, TA; Feigenson, GW; Heberle, FA; Wu, J | 1 |
| Chełminiak-Dudkiewicz, D; Martyński, T; Piosik, E; Ziegler-Borowska, M | 1 |
| Battista, F; Del Vecchio, P; Oliva, R; Petraccone, L; Winter, R | 1 |
| Bonarek, P; Chmielińska, A; Dziedzicka-Wasylewska, M; Enkavi, G; Girych, M; Polit, A; Rog, T; Stepien, P | 1 |
| Baptista, MS; Junqueira, H; Klymchenko, A; Marques, CM; Mély, Y; Schroder, AP; Thalmann, F | 1 |
| Baba, T; Chelur, A; Chen, K; Chernushevich, I; Duchoslav, E; Loyd, B; Ryumin, P | 1 |
| Blackmond, DG; Cochrane, WG; Hu, J; Jones, AX; Paegel, BM | 1 |
| Berglund, N; Hsu, JP; Ravnkilde, LK; Schiøtt, B; Stange, AD | 1 |
| Akamatsu, M; Bhadani, A; Kafle, A; Kaise, C; Kaneko, T; Sakai, H; Sakai, K; Tanaka, R | 1 |
| Gong, C; Li, D; Wang, J; Xing, D; Zhang, D; Zhang, X; Zhao, L | 1 |
| Aydin, F; da Hora, GCA; Durumeric, AEP; Nguyen, JDM; Oh, MI; Swanson, JMJ | 1 |
| Aguayo-Ortiz, R; Creech, J; da Rocha, AM; Espinoza-Fonseca, LM; Guerrero-Serna, G; Herron, TJ; Jiménez-Vázquez, EN; Wang, N | 1 |
| Caparotta, M; Masone, D | 1 |
| Jiaranaikulwanitch, J; Jiranusornkul, S; Saenjum, C; Vajragupta, O; Wongrattanakamon, P; Yooin, W | 1 |
| Bacle, A; Buslaev, P; Favela-Rosales, F; Fuchs, PFJ; Garcia-Fandino, R; Gushchin, I; Javanainen, M; Kiirikki, AM; Madsen, JJ; Melcr, J; Mendes Ferreira, T; Miettinen, MS; Milán Rodríguez, P; Ollila, OHS; Papadopoulos, CG; Peón, A; Piggot, TJ; Piñeiro, Á; Virtanen, SI | 1 |
| Hao, C; Sun, R; Xie, B | 1 |
| Alvarez, AB; Fidelio, GD; Rodríguez, PEA | 1 |
| Ausili, A; Gómez-Fernández, JC; Teruel, JA; Yakymenko, I | 1 |
| Ambe, CE; Balanay, MP; Barredo, PA; Fernandez, MJF | 1 |
| Belousov, R; Franklin-Mergarejo, R; Girotto, I; Goliaei, EM; Güell, O; Hassanali, A; Qaisrani, MN; Rehman, JU; Roldán, É | 1 |
| Cavasso, D; Menichetti, L; Montesarchio, D; Paduano, L; Petroni, D; Riccardi, C; Russo Krauss, I | 1 |
| Aisenbrey, C; Bechinger, B; Salnikov, E | 1 |
| Bazak, J; Girotti, AW; Korytowski, W; Pabisz, P | 1 |
| Cwiklik, L; Dolejšová, T; Fišer, R; Riedlová, K | 1 |
| Engberg, O; Hildebrand, PW; Huster, D; Smith, AA; Vogel, A | 1 |
| Black, KA; Bolla, JR; Clarke, OB; Colman, PM; Czabotar, P; Gulbis, JM; He, S; Jin, R; Johnson, P; Laver, D; Periasamy, A; Robinson, CV; Smith, BJ; Wardak, A; Wu, D | 1 |
| Hamada, N; Longo, ML | 1 |
| Bartos, P; Kurki, M; Miettinen, MS; Poso, A | 1 |
| Heftberger, P; Javanainen, M; Madsen, JJ; Miettinen, MS; Ollila, OHS; Pabst, G | 1 |
4 review(s) available for phosphatidylcholines and 1-palmitoyl-2-oleoylphosphatidylcholine
| Article | Year |
|---|---|
Endogenous ligand for an orphan receptor.
Topics: Animals; Carbohydrate Metabolism; Gene Expression Regulation, Enzymologic; Humans; Ligands; Lipid Metabolism; Phosphatidylcholines; PPAR alpha | 2010 |
Molecular dynamics simulation of membrane proteins.
Topics: Aquaporins; Cell Membrane; ErbB Receptors; Kinetics; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Conformation; Protein Multimerization; Receptors, Opioid, delta; Thermodynamics | 2014 |
Functionalized lipids and surfactants for specific applications.
Topics: Drug Delivery Systems; Lipid Bilayers; Lipids; Molecular Dynamics Simulation; Phosphatidylcholines; Sphingomyelins; Spin Labels; Structure-Activity Relationship; Surface-Active Agents; Transfection | 2016 |
Roles of Reconstituted High-Density Lipoprotein Nanoparticles in Cardiovascular Disease: A New Paradigm for Drug Discovery.
Topics: Animals; Apolipoprotein A-I; Atherosclerosis; ATP Binding Cassette Transporter 1; Biomimetics; Drug Discovery; Humans; Lipoproteins, HDL; Macrophages; Mice; Molecular Imaging; Nanoparticles; Phosphatidylcholines | 2020 |
3 trial(s) available for phosphatidylcholines and 1-palmitoyl-2-oleoylphosphatidylcholine
| Article | Year |
|---|---|
Turnover of exogenous artificial surfactant.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Birth Weight; Chromatography, High Pressure Liquid; Drug Combinations; Fatty Alcohols; Gestational Age; Humans; Infant, Newborn; Intubation, Intratracheal; Phosphatidylcholines; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1992 |
Surfactant phosphatidylcholine composition during dexamethasone treatment in chronic lung disease.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Analysis of Variance; Chronic Disease; Dexamethasone; Double-Blind Method; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Lung Diseases; Phosphatidylcholines; Pulmonary Surfactants; Time Factors | 1994 |
Safety and pharmacokinetics of a recombinant factor VIII with pegylated liposomes in severe hemophilia A.
Topics: Adolescent; Adult; Biological Availability; Cholesterol; Cholesterol, LDL; Complement C3a; Complement Hemolytic Activity Assay; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Factor VIII; Half-Life; Hemophilia A; Hemorrhagic Disorders; Humans; Infusions, Intravenous; Liposomes; Male; Metabolic Clearance Rate; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; Recombinant Proteins | 2008 |
1943 other study(ies) available for phosphatidylcholines and 1-palmitoyl-2-oleoylphosphatidylcholine
| Article | Year |
|---|---|
Phase diagram of a polyunsaturated lipid mixture: Brain sphingomyelin/1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine/cholesterol.
Topics: Animals; Brain Chemistry; Cholesterol; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Lipid Bilayers; Membrane Microdomains; Microscopy, Fluorescence; Phase Transition; Phosphatidylcholines; Sphingomyelins; Swine; Unilamellar Liposomes | 2016 |
Amyloid-β(29-42) Dimeric Conformations in Membranes Rich in Omega-3 and Omega-6 Polyunsaturated Fatty Acids.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Lipid Bilayers; Molecular Dynamics Simulation; Peptide Fragments; Phosphatidylcholines; Protein Conformation, alpha-Helical; Protein Structure, Quaternary; Thermodynamics | 2019 |
Enzymatic and physical characterization of diacylglycerol-phosphatidylcholine interactions in bilayers and monolayers.
Topics: Calorimetry, Differential Scanning; Diglycerides; Freeze Fracturing; Glycerides; Hydrolysis; Lipid Bilayers; Phosphatidylcholines | 1989 |
Fourier-transform infrared studies of CaATPase partitioning in phospholipid mixtures of 1,2-dipalmitoylphosphatidylcholine-d62 with 1-palmitoyl-2-oleoylphosphatidylethanolamine and 1-stearoyl-2-oleoylphosphatidylcholine.
Topics: Animals; Calcium-Transporting ATPases; Calorimetry, Differential Scanning; Fourier Analysis; Kinetics; Lipid Bilayers; Muscles; Phosphatidylcholines; Pulmonary Surfactants; Rabbits; Sarcoplasmic Reticulum; Spectrophotometry, Infrared; Structure-Activity Relationship; Thermodynamics | 1985 |
Is lateral phase separation required for fatty acid to stimulate lipases in a phosphatidylcholine interface?
Topics: Chemical Phenomena; Chemistry, Physical; Fatty Acids; Fatty Acids, Unsaturated; Lipase; Lysophosphatidylcholines; Oxygen; Phosphatidylcholines | 1994 |
Lipid headgroup spacing and peptide penetration, but not peptide oligomerization, modulate peptide-induced fusion.
Topics: Egg Yolk; Glycerides; Lipid Bilayers; Lysophosphatidylcholines; Membrane Fusion; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Temperature | 1999 |
Effects of hypochlorous acid on unsaturated phosphatidylcholines.
Topics: Chlorides; Chlorohydrins; Fatty Acids, Unsaturated; Glycols; Hydrogen Peroxide; Hypochlorous Acid; Peroxidase; Phosphatidylcholines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2001 |
Peptide-induced formation of cholesterol-rich domains.
Topics: Calorimetry, Differential Scanning; Carbohydrate Sequence; Carbon Isotopes; Cholesterol; Crystallization; Lipid Bilayers; Liposomes; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Phosphatidylcholines; Protein Structure, Tertiary; Protons; Spectrometry, Fluorescence; Thermodynamics; Tryptophan | 2003 |
Barotropic and thermotropic bilayer phase behavior of positional isomers of unsaturated mixed-chain phosphatidylcholines.
Topics: Biophysical Phenomena; Calorimetry, Differential Scanning; Ethylene Glycol; Isomerism; Lipid Bilayers; Phase Transition; Phosphatidylcholines; Pressure; Thermodynamics | 2009 |
Comparison of three ternary lipid bilayer mixtures: FRET and ESR reveal nanodomains.
Topics: Cholesterol; Electron Spin Resonance Spectroscopy; Ergosterol; Fluorescence Resonance Energy Transfer; Lipid Bilayers; Membrane Microdomains; Phase Transition; Phosphatidylcholines; Porphobilinogen; Surface Properties | 2010 |
Using micropatterned lipid bilayer arrays to measure the effect of membrane composition on merocyanine 540 binding.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Algorithms; Binding, Competitive; Cell Membrane; Chlorobenzenes; Cholesterol; Dimyristoylphosphatidylcholine; Gels; Kinetics; Lipid Bilayers; Microarray Analysis; Microscopy, Fluorescence; Molecular Structure; Phase Transition; Phosphatidylcholines; Pyrimidinones; Reproducibility of Results; Spectrometry, Fluorescence | 2011 |
Sphingomyelin/phosphatidylcholine/cholesterol monolayers--analysis of the interactions in model membranes and Brewster Angle Microscopy experiments.
Topics: Cholesterol; Erythrocyte Membrane; Membrane Microdomains; Membranes, Artificial; Microscopy; Phosphatidylcholines; Sphingomyelins; Surface Properties; Thermodynamics | 2012 |
Back to the future: mechanics and thermodynamics of lipid biomembranes.
Topics: Cell Membrane; Cholesterol; Dimyristoylphosphatidylcholine; Elasticity; Lipid Bilayers; Membrane Lipids; Phosphatidylcholines; Thermodynamics | 2013 |
Geometric rules of channel gating inferred from computational models of the P2X receptor transmembrane domain.
Topics: Adenosine Triphosphate; Amino Acid Motifs; Animals; Binding Sites; Crystallography, X-Ray; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Kinetics; Lipid Bilayers; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Sequence Data; Phosphatidylcholines; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Purinergic P2X; Thermodynamics; Zebrafish | 2015 |
Interleaflet mixing and coupling in liquid-disordered phospholipid bilayers.
Topics: Dimyristoylphosphatidylcholine; Lipid Bilayers; Phosphatidylcholines | 2016 |
Determination of electrostatic potentials at biological interfaces using electron-electron double resonance.
Topics: Aminacrine; DNA; Electrochemistry; Electron Spin Resonance Spectroscopy; Mathematics; Membrane Potentials; Models, Molecular; Models, Theoretical; Molecular Conformation; Nucleic Acid Conformation; Phosphatidylcholines; Phosphatidylglycerols; Proteins; Spin Labels | 1992 |
Motional narrowing of the 2H NMR spectra near the chain melting transition of phospholipid/D2O mixtures.
Topics: Deuterium; Deuterium Oxide; Magnetic Resonance Spectroscopy; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; Thermodynamics; Water | 1992 |
Interaction of a substance P agonist and of substance P antagonists with lipid membranes. A thermodynamic analysis.
Topics: Adsorption; Amino Acid Sequence; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Electrochemistry; Lipid Bilayers; Membrane Lipids; Membranes, Artificial; Micelles; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Spectrometry, Fluorescence; Substance P; Surface Properties; Thermodynamics | 1992 |
Properties of the mitochondrial peptide-sensitive cationic channel studied in planar bilayers and patches of giant liposomes.
Topics: Adrenal Cortex; Animals; Cattle; Electric Conductivity; Ion Channels; Lipid Bilayers; Liposomes; Membrane Potentials; Mitochondria; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Proteolipids; Saccharomyces cerevisiae; Trypsin | 1992 |
Hydration at the membrane protein-lipid interface.
Topics: Apoproteins; Cholesterol; Cytochrome c Group; Cytochromes c; Gramicidin; Lipid Bilayers; Membrane Lipids; Membrane Proteins; Phosphatidylcholines; Spectrometry, Fluorescence; Water | 1992 |
Conformation of phosphatidylcholine in neat and cholesterol-containing liquid-crystalline bilayers. Application of a novel method.
Topics: Chemistry, Physical; Cholesterol; Lipid Bilayers; Models, Chemical; Molecular Conformation; Phosphatidylcholines; Pyrenes | 1992 |
Peptide binding to lipid bilayers. Nonclassical hydrophobic effect and membrane-induced pK shifts.
Topics: Amino Acid Sequence; Calorimetry; Fluorescent Dyes; Hydrogen-Ion Concentration; Lipid Bilayers; Liposomes; Molecular Sequence Data; Naphthalenesulfonates; Octreotide; Phosphatidylcholines; Phosphatidylglycerols; Thermodynamics | 1992 |
Kinetics of melittin induced pore formation in the membrane of lipid vesicles.
Topics: Ion Channel Gating; Kinetics; Lipid Bilayers; Mathematics; Melitten; Models, Biological; Phosphatidylcholines | 1992 |
Effect of diolein on hydrolysis of phosphatidylcholine by phospholipase C from Clostridium perfringens.
Topics: Clostridium perfringens; Diglycerides; Hydrolysis; Phosphatidylcholines; Type C Phospholipases | 1992 |
Spontaneous transfer of ganglioside GM1 from its micelles to lipid vesicles of differing size.
Topics: Chromatography, Liquid; Freeze Fracturing; G(M1) Ganglioside; Lipid Bilayers; Micelles; Microscopy, Electron; Phosphatidylcholines | 1992 |
Shaking stack model of ion conduction through the Ca(2+)-activated K+ channel.
Topics: Animals; Calcium; Electric Conductivity; Kinetics; Lipid Bilayers; Mathematics; Membrane Potentials; Models, Biological; Muscles; Phosphatidylcholines; Phosphatidylethanolamines; Potassium Channels; Rats | 1992 |
Activation energy and entropy for intramolecular excimer formation in a dipyrenylphosphatidylcholine probe in lamellar and hexagonal lipid phases.
Topics: Lipids; Molecular Probes; Phosphatidylcholines; Phosphatidylethanolamines; Spectrometry, Fluorescence; Thermodynamics | 1992 |
Interactions of aminoglycoside antibiotics with phospholipids. A deuterium nuclear magnetic resonance study.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Aminoglycosides; Anti-Bacterial Agents; Carbohydrate Sequence; Humans; Kidney; Liposomes; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Phosphatidylcholines; Phosphatidylinositols; Phospholipids | 1992 |
Lateral lipid distribution is a major regulator of lipase activity. Implications for lipid-mediated signal transduction.
Topics: Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Fatty Acids, Unsaturated; Homeostasis; Kinetics; Lipase; Liposomes; Mathematics; Models, Theoretical; Oxygen Isotopes; Pancreas; Phosphatidylcholines; Signal Transduction; Surface Properties; Swine | 1992 |
The charge and structural stability of apolipoprotein A-I in discoidal and spherical recombinant high density lipoprotein particles.
Topics: Apolipoprotein A-I; Calorimetry; Cholesterol Esters; Circular Dichroism; Guanidine; Guanidines; Humans; Kinetics; Lipoproteins, HDL; Liposomes; Mathematics; Models, Structural; Models, Theoretical; Phosphatidylcholines; Protein Conformation; Protein Denaturation; Protein Structure, Secondary; Recombinant Proteins | 1992 |
Comparison of the lipid acyl chain dynamics between small and large unilamellar vesicles.
Topics: Carbon Isotopes; Hydrogen; Liposomes; Magnetic Resonance Spectroscopy; Mathematics; Microscopy, Electron; Models, Biological; Molecular Conformation; Phosphatidylcholines; Structure-Activity Relationship; Thermodynamics | 1992 |
Effect of phosphorylation on receptor conformation: the metarhodopsin I in equilibrium with metarhodopsin II equilibrium in multiply phosphorylated rhodopsin.
Topics: Animals; Cattle; Hydrogen-Ion Concentration; Kinetics; Liposomes; Phosphatidylcholines; Phosphorylation; Protein Conformation; Rhodopsin; Rod Cell Outer Segment; Signal Transduction; Spectrophotometry; Thermodynamics | 1992 |
Regulation of fatty acid 18O exchange catalyzed by pancreatic carboxylester lipase. 2. Effects of lateral lipid distribution in mixtures with phosphatidylcholine.
Topics: Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Catalysis; Docosahexaenoic Acids; Kinetics; Oxygen Isotopes; Pancreas; Phosphatidylcholines; Substrate Specificity; Swine | 1992 |
Cholesterol oxidase susceptibility of cholesterol and 5-androsten-3 beta-ol in pure sterol monolayers and in mixed monolayers containing 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine.
Topics: 1-Propanol; Androstenols; Cholesterol; Cholesterol Oxidase; Fluorometry; Kinetics; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Solvents; Surface Properties; Water | 1992 |
Analysis of cell membrane micro-heterogeneity using the fluorescence lifetime of DPH-type fluorophores.
Topics: Animals; Cell Membrane; Cytochromes b5; Diphenylhexatriene; Fluorescent Dyes; Lipid Bilayers; Liver; Microsomes, Liver; Phosphatidylcholines; Rats | 1992 |
Cholesterol modulation of lipid intermixing in phospholipid and glycosphingolipid mixtures. Evaluation using fluorescent lipid probes and brominated lipid quenchers.
Topics: Animals; Brain Chemistry; Bromine; Calorimetry, Differential Scanning; Cattle; Chemical Phenomena; Chemistry, Physical; Cholesterol; Fluorescent Dyes; Glycosphingolipids; Lipid Bilayers; Lipids; Molecular Structure; Phosphatidic Acids; Phosphatidylcholines; Phospholipids; Spectrometry, Fluorescence | 1992 |
Interaction of lysophospholipid/taurodeoxycholate submicellar aggregates with phospholipid bilayers.
Topics: Fluorescent Dyes; Lipid Bilayers; Liposomes; Lysophospholipids; Micelles; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Spectrometry, Fluorescence; Taurodeoxycholic Acid | 1992 |
Sterol domains in phospholipid membranes: dehydroergosterol polarization measures molecular sterol transfer.
Topics: Biological Transport; Carrier Proteins; Ergosterol; Fluorescence Polarization; Kinetics; Lipid Bilayers; Membrane Fluidity; Membrane Lipids; Phosphatidylcholines; Phospholipids; Plant Proteins | 1992 |
Phosphatidylcholine composition of endotracheal tube aspirates of neonates and subsequent respiratory disease.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Chromatography, High Pressure Liquid; Chronic Disease; Gestational Age; Humans; Infant; Infant, Newborn; Intubation, Intratracheal; Lung Diseases; Phosphatidylcholines; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1992 |
Combined influence of cholesterol and synthetic amphiphillic peptides upon bilayer thickness in model membranes.
Topics: Biomechanical Phenomena; Biophysical Phenomena; Biophysics; Cholesterol; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membranes, Artificial; Models, Chemical; Molecular Conformation; Peptides; Phosphatidylcholines | 1992 |
Temperature-reversible eruptions of vesicles in model membranes studied by NMR.
Topics: Biophysical Phenomena; Biophysics; Cholesterol; Freeze Fracturing; Magnetic Resonance Spectroscopy; Membranes, Artificial; Microscopy, Electron; Models, Biological; Phosphatidylcholines; Phosphatidylserines; Temperature | 1992 |
Surface binding kinetics of prothrombin fragment 1 on planar membranes measured by total internal reflection fluorescence microscopy.
Topics: Animals; Calcium; Cattle; Fluorescein; Fluoresceins; Fluorescent Dyes; Glycerol; Kinetics; Light; Liposomes; Microscopy, Fluorescence; Peptide Fragments; Phosphatidylcholines; Phosphatidylserines; Protein Precursors; Prothrombin; Scattering, Radiation; Solutions | 1992 |
Microscopic versus macroscopic diffusion in model membranes by electron spin resonance spectral-spatial imaging.
Topics: Cyclic N-Oxides; Diffusion; Electron Spin Resonance Spectroscopy; Mathematics; Membranes, Artificial; Models, Biological; Phosphatidylcholines; Spin Labels | 1991 |
Influence of stigmastanol and stigmastanyl-phosphorylcholine, two plasma cholesterol lowering substances, on synthetic phospholipid membranes. A 2H- and 31P-NMR study.
Topics: Cholesterol; Hypolipidemic Agents; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membranes, Artificial; Phosphatidylcholines; Phospholipids; Phosphorus Isotopes; Phosphorylcholine; Sitosterols | 1992 |
Investigation of anion binding to neutral lipid membranes using 2H NMR.
Topics: Anions; Binding Sites; Deuterium; Lipid Bilayers; Magnetic Resonance Spectroscopy; Osmolar Concentration; Phosphatidylcholines; Sodium Hypochlorite; Sodium Iodide; Sodium Nitrite; Thiocyanates | 1992 |
Shape transitions and shape stability of giant phospholipid vesicles in pure water induced by area-to-volume changes.
Topics: Dimyristoylphosphatidylcholine; Mathematics; Models, Biological; Molecular Conformation; Phosphatidylcholines; Thermodynamics; Water | 1991 |
Orientation of melittin in phospholipid bilayers. A polarized attenuated total reflection infrared study.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Kinetics; Lipid Bilayers; Mathematics; Melitten; Models, Theoretical; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Spectrophotometry, Infrared | 1991 |
Membrane binding induces lipid-specific changes in the denaturation profile of bovine prothrombin. A scanning calorimetry study.
Topics: Animals; Calorimetry, Differential Scanning; Cattle; Kinetics; Liposomes; Models, Theoretical; Peptide Fragments; Phosphatidylcholines; Protein Binding; Protein Conformation; Protein Denaturation; Prothrombin | 1991 |
Interaction of electric dipoles with phospholipid head groups. A 2H and 31P NMR study of phloretin and phloretin analogues in phosphatidylcholine membranes.
Topics: Cholesterol; Deuterium; Deuterium Oxide; Kinetics; Magnetic Resonance Spectroscopy; Membranes, Artificial; Molecular Conformation; Phloretin; Phosphatidylcholines; Phosphorus; Structure-Activity Relationship; Water | 1991 |
Effect of pancreatic phospholipase A2 and gastric lipase on the action of pancreatic carboxyl ester lipase against lipid substrates in vitro.
Topics: Carboxylesterase; Carboxylic Ester Hydrolases; Cholesterol Esters; Emulsions; Gastric Juice; Humans; Hydrolysis; Kinetics; Lipase; Pancreas; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Substrate Specificity; Triolein | 1991 |
Reactions of dinitrogen pentoxide and nitrogen dioxide with 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine.
Topics: Chromatography, High Pressure Liquid; Fourier Analysis; Models, Biological; Nitrogen Dioxide; Nitrogen Oxides; Phosphatidylcholines; Pulmonary Surfactants; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared | 1991 |
Calcium binding by phosphatidylserine headgroups. Deuterium NMR study.
Topics: Calcium; Deuterium; Liposomes; Magnetic Resonance Spectroscopy; Models, Biological; Molecular Conformation; Phosphatidylcholines; Phosphatidylserines; Thermodynamics | 1991 |
Effective charge of melittin upon interaction with POPC vesicles.
Topics: Amino Acid Sequence; Circular Dichroism; Electrophoresis; Magnetic Resonance Spectroscopy; Melitten; Membrane Potentials; Molecular Sequence Data; Phosphatidylcholines | 1991 |
Structural determinants of miscibility in surface films of galactosylceramide and phosphatidylcholine: effect of unsaturation in the galactosylceramide acyl chain.
Topics: Animals; Brain; Cattle; Galactosylceramides; Membrane Potentials; Phosphatidylcholines; Pressure; Solubility; Structure-Activity Relationship; Surface Properties | 1991 |
Secondary structure and orientation of the amphipathic peptide GALA in lipid structures. An infrared-spectroscopic approach.
Topics: Amino Acid Sequence; Apolipoproteins; Dimyristoylphosphatidylcholine; Lipid Bilayers; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Conformation; Solubility; Spectrophotometry, Infrared | 1991 |
Stabilization of non-bilayer structures by the etherlipid ethanolamine plasmalogen.
Topics: Kinetics; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Plasmalogens; Sensitivity and Specificity; X-Ray Diffraction | 1991 |
Bilayer packing stress and defects in mixed dilinoleoylphosphatidylethanolamine and palmitoyloleoylphosphatidylcholine and their susceptibility to phospholipase A2.
Topics: Animals; Cholesterol; Enzyme Activation; Freeze Fracturing; Hydrolysis; Kinetics; Lipid Bilayers; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Swine | 1991 |
Modulation of the orientational order profile of the lipid acyl chain in the L alpha phase.
Topics: Cell Membrane; Chemical Phenomena; Chemistry, Physical; Cholesterol; Lipid Bilayers; Lipids; Magnetic Resonance Spectroscopy; Membrane Lipids; Molecular Conformation; Phosphatidylcholines; Temperature | 1990 |
Interactions of different lipid species in multicomponent membranes.
Topics: Lipid Bilayers; Membrane Lipids; Membranes; Models, Biological; Phosphatidylcholines; Phospholipids; Spectrometry, Fluorescence; Structure-Activity Relationship | 1990 |
Factors affecting solute entrapment in phospholipid vesicles prepared by the freeze-thaw extrusion method: a possible general method for improving the efficiency of entrapment.
Topics: Calcium; Carbon Radioisotopes; Freezing; Lipid Bilayers; Membranes, Artificial; Osmolar Concentration; Phosphatidylcholines; Phospholipids; Sodium Chloride; Solutions; Sucrose; Tetraethylammonium; Tetraethylammonium Compounds | 1990 |
Fluorescence lifetime distributions of parinaroyl phospholipids in choline plasmalogen and phosphatidylcholine bilayers containing different amounts of cholesterol.
Topics: Cholesterol; Fluorescent Dyes; Lipid Bilayers; Liposomes; Phosphatidylcholines; Plasmalogens; Spectrometry, Fluorescence | 1990 |
Apolipoprotein A-I structure and lipid properties in homogeneous, reconstituted spherical and discoidal high density lipoproteins.
Topics: Antibodies, Monoclonal; Apolipoprotein A-I; Apolipoproteins A; Cholesterol; Circular Dichroism; Humans; Kinetics; Lipoproteins, HDL; Liposomes; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Thermodynamics | 1990 |
Dynamics of phosphatidylcholine-cholesterol mixed model membranes in the liquid crystalline state.
Topics: Cholesterol; Diffusion; Dimyristoylphosphatidylcholine; Electron Spin Resonance Spectroscopy; Mathematics; Membranes, Artificial; Models, Biological; Phosphatidylcholines; Spectrophotometry; Thermodynamics | 1990 |
Organization and interaction of cholesterol and phosphatidylcholine in model bilayer membranes.
Topics: Buffers; Chemical Phenomena; Chemistry, Physical; Cholestenes; Cholesterol; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Liposomes; Membranes, Artificial; Models, Biological; Phosphatidylcholines; Pressure; Spectrometry, Fluorescence; Spectrophotometry; Sterols; Time Factors | 1990 |
Secondary structure of a mitochondrial signal peptide in lipid bilayer membranes.
Topics: Amino Acid Sequence; Animals; Cardiolipins; Cattle; Circular Dichroism; Electron Transport Complex IV; Lipid Bilayers; Membrane Lipids; Mitochondria, Heart; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Protein Sorting Signals | 1990 |
Membrane insertion and lateral diffusion of fluorescence-labelled cytochrome c oxidase subunit IV signal peptide in charged and uncharged phospholipid bilayers.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Diffusion; Electron Transport Complex IV; Fluorescent Dyes; Kinetics; Lipid Bilayers; Macromolecular Substances; Molecular Sequence Data; Oxadiazoles; Phosphatidylcholines; Phosphatidylglycerols; Protein Sorting Signals; Spectrometry, Fluorescence; Structure-Activity Relationship | 1990 |
Use of a new simplified assay for phospholipase A2 to measure bacterial enzyme levels.
Topics: Carbon Radioisotopes; Escherichia coli; Hydrogen-Ion Concentration; Hydrolysis; Lactobacillus; Oleic Acid; Oleic Acids; Phosphatidylcholines; Phospholipases; Phospholipases A; Phospholipases A2; Streptococcus agalactiae; Time Factors | 1990 |
Ca2+, Mg2+, Li+, Na+, and K+ distributions in the headgroup region of binary membranes of phosphatidylcholine and phosphatidylserine as seen by deuterium NMR.
Topics: Binding Sites; Calcium; Cations, Divalent; Cations, Monovalent; Deuterium; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Conformation; Peptides; Phosphatidylcholines; Phosphatidylserines | 1990 |
Binding of pancreatic carboxylester lipase to mixed lipid films. Implications for surface organization.
Topics: Adsorption; Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Diglycerides; Fatty Acids; Hydrolysis; Lipid Metabolism; Oleic Acid; Oleic Acids; Pancreas; Phosphatidylcholines; Surface Properties; Swine; Triglycerides | 1990 |
Interaction of fluorescent delta 5,7,9(11),22-ergostatetraen-3 beta-ol with sterol carrier protein-2.
Topics: Animals; Carrier Proteins; Cholesterol; Energy Transfer; Ergosterol; Fluorescence Polarization; Light; Liposomes; Liver; Microsomes, Liver; Phosphatidylcholines; Plant Proteins; Protein Binding; Rats; Scattering, Radiation; Sterol O-Acyltransferase; Sterols; Tryptophan | 1990 |
Melittin binding to mixed phosphatidylglycerol/phosphatidylcholine membranes.
Topics: Bee Venoms; Choline; Circular Dichroism; Deuterium; Electrochemistry; Magnetic Resonance Spectroscopy; Melitten; Membrane Lipids; Membranes, Artificial; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Conformation | 1990 |
Mechanism of spontaneous, concentration-dependent phospholipid transfer between bilayers.
Topics: Cholesterol; Kinetics; Lipid Bilayers; Phosphatidylcholines; Phospholipids; Potassium Chloride; Temperature | 1990 |
Sizing of lecithin-bile salt mixed micelles by size-exclusion high-performance liquid chromatography.
Topics: Bile Acids and Salts; Chromatography, High Pressure Liquid; Deoxycholic Acid; Micelles; Models, Chemical; Molecular Structure; Particle Size; Phosphatidylcholines | 1990 |
Trapping single ions inside single ion channels.
Topics: Animals; Calcium; Ion Channels; Ions; Lipid Bilayers; Models, Biological; Muscles; Phosphatidylcholines; Potassium; Rats | 1987 |
Binding of a neuropeptide, substance P, to neutral and negatively charged lipids.
Topics: Glycerophosphates; Kinetics; Liposomes; Mathematics; Models, Theoretical; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Substance P | 1989 |
Antimicrobial peptide magainin I from Xenopus skin forms anion-permeable channels in planar lipid bilayers.
Topics: Amino Acid Sequence; Animals; Anti-Infective Agents; Antimicrobial Cationic Peptides; Circular Dichroism; Electric Conductivity; Ion Channels; Lipid Bilayers; Models, Biological; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Protein Conformation; Skin; Xenopus laevis; Xenopus Proteins | 1989 |
Dynamic imaging of lateral diffusion by electron spin resonance and study of rotational dynamics in model membranes. Effect of cholesterol.
Topics: Cholesterol; Diffusion; Electron Spin Resonance Spectroscopy; Liposomes; Mathematics; Models, Theoretical; Phosphatidylcholines; Rotation; Spin Labels | 1989 |
Calcium ion binding between lipid bilayers: the four-component system of phosphatidylserine, phosphatidylcholine, calcium chloride, and water.
Topics: Calcium Chloride; Electron Spin Resonance Spectroscopy; Kinetics; Lipid Bilayers; Models, Theoretical; Molecular Conformation; Phosphatidylcholines; Phosphatidylserines; Water; X-Ray Diffraction | 1989 |
Thermodynamics of phosphatidylcholine-cholesterol mixed model membranes in the liquid crystalline state studied by the orientational order parameter.
Topics: Cholesterol; Crystallization; Dimyristoylphosphatidylcholine; Electron Spin Resonance Spectroscopy; Liposomes; Mathematics; Models, Biological; Molecular Conformation; Phosphatidylcholines; Thermodynamics | 1989 |
Discoidal complexes containing apolipoprotein E and their transformation by lecithin-cholesterol acyltransferase.
Topics: Apolipoproteins E; Chemical Phenomena; Chemistry, Physical; Cholesterol; Cholic Acid; Cholic Acids; Dialysis; Electrophoresis, Polyacrylamide Gel; Humans; Immunoblotting; Lecithin Cholesterol Acyltransferase Deficiency; Lipoproteins, HDL; Microscopy, Electron; Particle Size; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines; Ultracentrifugation | 1989 |
Smoothed orientational order profile of lipid bilayers by 2H-nuclear magnetic resonance.
Topics: Deuterium; Lipid Bilayers; Magnetic Resonance Spectroscopy; Mathematics; Models, Biological; Molecular Conformation; Phosphatidylcholines | 1989 |
Fluorescence lifetime distributions of diphenylhexatriene-labeled phosphatidylcholine as a tool for the study of phospholipid-cholesterol interactions.
Topics: Cholesterol; Lipid Bilayers; Liposomes; Mathematics; Models, Biological; Molecular Conformation; Phosphatidylcholines; Spectrometry, Fluorescence | 1989 |
Structure and conformational analysis of lipid-associating peptides of apolipoprotein B-100 produced by trypsinolysis.
Topics: Amino Acid Sequence; Amino Acids; Apolipoproteins B; Binding Sites; Circular Dichroism; Dimyristoylphosphatidylcholine; Humans; Lipid Metabolism; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Protein Conformation; Sphingomyelins; Trypsin | 1989 |
Spontaneous phosphatidylcholine transfer by collision between vesicles at high lipid concentration.
Topics: Kinetics; Liposomes; Membrane Fusion; Models, Theoretical; Phosphatidylcholines | 1989 |
Metabolism of intratracheally administered unsaturated phosphatidylcholines in adult rabbits.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Administration, Oral; Animals; Carbon Radioisotopes; Kinetics; Liposomes; Lung; Microsomes; Organelles; Phosphatidylcholines; Rabbits; Radioisotope Dilution Technique; Tritium | 1989 |
Lysophosphatidylcholine stabilizes small unilamellar phosphatidylcholine vesicles. Phosphorus-31 NMR evidence for the "wedge" effect.
Topics: Lipid Bilayers; Liposomes; Lysophosphatidylcholines; Magnetic Resonance Spectroscopy; Models, Theoretical; Molecular Conformation; Phosphatidylcholines | 1989 |
Spontaneous transfer between phospholipid bilayers of dehydroergosterol, a fluorescent cholesterol analog.
Topics: Cholesterol Esters; Ergosterol; Kinetics; Lipid Bilayers; Phosphatidylcholines; Spectrometry, Fluorescence; Sphingomyelins | 1989 |
A new model to describe extrinsic protein binding to phospholipid membranes of varying composition: application to human coagulation proteins.
Topics: Factor X; Humans; Lipid Bilayers; Membrane Proteins; Models, Biological; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Phospholipids; Protein Binding; Prothrombin | 1989 |
Estimated conformation, orientation, and accumulation of dynorphin A-(1-13)-tridecapeptide on the surface of neutral lipid membranes.
Topics: Dynorphins; Liposomes; Mathematics; Peptide Fragments; Phosphatidylcholines; Protein Conformation; Thermodynamics | 1986 |
Photodynamic action of merocyanine 540 on artificial and natural cell membranes: involvement of singlet molecular oxygen.
Topics: Cell Line; Cell Membrane; Dimyristoylphosphatidylcholine; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Fluorescent Dyes; Humans; Leukemia, Myeloid; Liposomes; Oxygen; Phosphatidylcholines; Photochemistry; Pyrimidinones; Singlet Oxygen | 1987 |
Incorporation and modification of exogenous phosphatidylcholines by mycoplasmas.
Topics: Chloramphenicol; Membrane Lipids; Mycoplasma; Mycoplasma pneumoniae; Phosphatidylcholines; Phospholipases A; Pulmonary Surfactants; Spiroplasma | 1986 |
Reaction of discoidal complexes of apolipoprotein A-I and various phosphatidylcholines with lecithin cholesterol acyltransferase. Interfacial effects.
Topics: Anions; Apolipoprotein A-I; Apolipoproteins A; Cholesterol; Fluorescence Polarization; Humans; Kinetics; Liposomes; Membrane Fluidity; Osmolar Concentration; Particle Size; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines; Protein Conformation; Sodium Chloride; Spectrometry, Fluorescence; Substrate Specificity; Thermodynamics | 1987 |
Transformation of large discoidal complexes of apolipoprotein A-I and phosphatidylcholine by lecithin-cholesterol acyltransferase.
Topics: Apolipoprotein A-I; Apolipoproteins A; Dimethyl Suberimidate; Electrophoresis, Polyacrylamide Gel; Humans; Immunodiffusion; Lipoproteins, HDL; Microscopy, Electron; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines | 1988 |
Determination of the phase behaviour of phosphatidylethanolamine admixed with other lipids and the effects of calcium chloride: implications for protein kinase C regulation.
Topics: Calcium Chloride; Calorimetry, Differential Scanning; Diglycerides; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Protein Kinase C | 1988 |
Anion binding to neutral and positively charged lipid membranes.
Topics: Anions; Binding Sites; Electrochemistry; In Vitro Techniques; Kinetics; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Quaternary Ammonium Compounds; Thiocyanates | 1988 |
Time-resolved fluorescence investigation of membrane cholesterol heterogeneity and exchange.
Topics: Cholesterol; Ergosterol; In Vitro Techniques; Kinetics; Liposomes; Membranes; Phosphatidylcholines; Spectrometry, Fluorescence | 1988 |
Fluorescence properties of cholestatrienol in phosphatidylcholine bilayer vesicles.
Topics: Cholestenes; Cholesterol; Kinetics; Lipid Bilayers; Models, Biological; Molecular Conformation; Phosphatidylcholines; Spectrometry, Fluorescence | 1988 |
Partitioning of local anesthetics into membranes: surface charge effects monitored by the phospholipid head-group.
Topics: Acetanilides; Adsorption; Dibucaine; Electrochemistry; Etidocaine; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Molecular Conformation; Phosphatidylcholines; Spectrophotometry, Ultraviolet | 1988 |
Deuterium NMR studies of the interactions of polyhydroxyl compounds and of glycolipids with lipid model membranes.
Topics: Ethylene Glycol; Ethylene Glycols; Glycerol; Glycolipids; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membranes, Artificial; Molecular Conformation; Phosphatidylcholines; Sorbitol; Trehalose | 1988 |
A fluorescence and radiolabel study of sterol exchange between membranes.
Topics: Cholesterol; Chromatography, Ion Exchange; Ergosterol; Fluorescence Polarization; Kinetics; Liposomes; Membranes, Artificial; Phosphatidylcholines; Scintillation Counting | 1988 |
Membrane structure of bombesin studied by infrared spectroscopy. Prediction of membrane interactions of gastrin-releasing peptide, neuromedin B, and neuromedin C.
Topics: Bombesin; Gastrin-Releasing Peptide; Hydrogen Bonding; Liposomes; Molecular Conformation; Neurokinin B; Neuropeptides; Peptide Fragments; Peptides; Phosphatidylcholines; Spectrophotometry, Infrared | 1987 |
Attenuated total reflectance Fourier transform infrared studies of the interaction of melittin, two fragments of melittin, and delta-hemolysin with phosphatidylcholines.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Bacterial Proteins; Bee Venoms; Circular Dichroism; Fourier Analysis; Hemolysin Proteins; Liposomes; Melitten; Molecular Conformation; Peptide Fragments; Phosphatidylcholines; Spectrophotometry, Infrared | 1987 |
Purification and characterization of phospholipase A2 from Trimeresurus gramineus venom.
Topics: Acetophenones; Amino Acid Sequence; Amino Acids; Calcium; Cations, Divalent; Chromatography; Crotalid Venoms; Enzyme Activation; Isoelectric Point; Kinetics; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Phosphatidylcholines; Phospholipases; Phospholipases A; Phospholipases A2 | 1987 |
Calcium binding to mixed phosphatidylglycerol-phosphatidylcholine bilayers as studied by deuterium nuclear magnetic resonance.
Topics: Calcium; Chemical Phenomena; Chemistry, Physical; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylglycerols; Spectrophotometry, Atomic; Structure-Activity Relationship | 1987 |
Local anesthetics and pressure: a comparison of dibucaine binding to lipid monolayers and bilayers.
Topics: Dibucaine; Kinetics; Lipid Bilayers; Liposomes; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Pressure; Structure-Activity Relationship; Surface Properties | 1987 |
Regulation of cholesteryl oleate and triolein miscibility in monolayers and bilayers.
Topics: Cholesterol Esters; Lipid Bilayers; Liposomes; Molecular Conformation; Phosphatidylcholines; Pressure; Surface Properties; Triolein | 1987 |
Inhibition of lecithin-cholesterol acyltransferase by diphytanoyl phosphatidylcholine.
Topics: Kinetics; Lipoproteins, HDL; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines | 1987 |
A fluorescence study of dehydroergosterol in phosphatidylcholine bilayer vesicles.
Topics: Cholesterol; Ergosterol; Kinetics; Lipid Bilayers; Models, Biological; Phosphatidylcholines; Spectrometry, Fluorescence | 1987 |
Characterization of phospholipase activities in chromaffin granule ghosts isolated from the bovine adrenal medulla.
Topics: Acylation; Adrenal Medulla; Animals; Cattle; Chromaffin Granules; Chromaffin System; Fatty Acids; Hydrogen-Ion Concentration; Hydrolysis; Intracellular Membranes; Lysophosphatidylcholines; Lysophospholipase; Membrane Lipids; Microsomes; Phosphatidylcholines; Phospholipases; Phospholipases A; Phospholipases A1; Phospholipases A2; Phospholipids | 1987 |
Spontaneous transfer of ganglioside GM1 between phospholipid vesicles.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Brain; Cattle; Cholesterol Esters; Chromatography, Gas; G(M1) Ganglioside; Kinetics; Lipid Bilayers; Liposomes; Phosphatidylcholines; Tritium | 1987 |
Dependence on phospholipid composition of the fraction of cholesterol undergoing spontaneous exchange between small unilamellar vesicles.
Topics: Carbon Radioisotopes; Cholesterol; Cholesterol Esters; Dimyristoylphosphatidylcholine; Kinetics; Liposomes; Phosphatidylcholines; Sphingomyelins; Tritium | 1987 |
Distributions of fluorescence decay times for parinaric acids in phospholipid membranes.
Topics: Dimyristoylphosphatidylcholine; Fatty Acids, Unsaturated; Fluorescent Dyes; Kinetics; Liposomes; Models, Biological; Phosphatidylcholines; Spectrometry, Fluorescence | 1987 |
Calcium binding to mixed cardiolipin-phosphatidylcholine bilayers as studied by deuterium nuclear magnetic resonance.
Topics: Calcium; Cardiolipins; Chemical Phenomena; Chemistry; Deuterium; Kinetics; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Biological; Phosphatidylcholines | 1987 |
Lipid-peptide association and activation of lecithin:cholesterol acyltransferase. Effect of alpha-helicity.
Topics: Amino Acid Sequence; Apolipoproteins; Circular Dichroism; Dimyristoylphosphatidylcholine; Enzyme Activation; Lipid Metabolism; Lipids; Lipoproteins, HDL; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines; Proline; Protein Conformation; Spectrometry, Fluorescence; Structure-Activity Relationship | 1986 |
The interactions of 1-palmitoyl-2-oleylphosphatidylcholine and bovine brain cerebroside.
Topics: Animals; Brain Chemistry; Calorimetry; Cattle; Cerebrosides; Gels; Membrane Fluidity; Membranes, Artificial; Phosphatidylcholines | 1986 |
The effects of cerebrosides on model membrane shape.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cerebrosides; Cholesterol; Magnetic Resonance Spectroscopy; Membranes, Artificial; Microscopy, Electron; Models, Biological; Molecular Conformation; Phosphatidylcholines | 1986 |
Fraction of cholesterol undergoing spontaneous exchange between small unilamellar phosphatidylcholine vesicles.
Topics: Cholesterol; Kinetics; Liposomes; Models, Biological; Phosphatidylcholines; Tritium | 1986 |
A novel method for encapsulation of macromolecules in liposomes.
Topics: Alkaline Phosphatase; Chemical Phenomena; Chemistry; Hemoglobins; Liposomes; Microscopy, Phase-Contrast; Phosphatidylcholines; Proteins; Sonication; Spectrometry, Fluorescence; Spectrophotometry; Surface Properties; Water | 1985 |
A comparison of the translational diffusion of a normal and a membrane-spanning lipid in L alpha phase 1-palmitoyl-2-oleoylphosphatidylcholine bilayers.
Topics: Archaea; Diffusion; Lipid Bilayers; Microscopy, Fluorescence; Models, Biological; Molecular Conformation; Phosphatidylcholines; Phospholipids; Thermodynamics | 1985 |
Characterization and activity of phospholipase A2 in normal human epidermis and in lesion-free epidermis of patients with psoriasis or eczema.
Topics: Adolescent; Adult; Aged; Calcium; Eczema; Epidermis; Female; Humans; Hydrogen-Ion Concentration; Hydrolysis; Male; Middle Aged; Phosphatidylcholines; Phospholipases; Phospholipases A; Phospholipases A2; Proteins; Psoriasis; Time Factors | 1985 |
The effects of pressure and cholesterol on rotational motions of perylene in lipid bilayers.
Topics: Benz(a)Anthracenes; Cholesterol; Dimyristoylphosphatidylcholine; Fluorescence Polarization; Lipid Bilayers; Liposomes; Perylene; Phosphatidylcholines; Pressure; Rotation; Temperature | 1985 |
Cellular uptake and intracellular localization of benzo(a)pyrene by digital fluorescence imaging microscopy.
Topics: Animals; Benzo(a)pyrene; Cell Line; Cell Membrane; Endocytosis; Fibroblasts; Humans; Kinetics; Lipid Metabolism; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Macrophages; Mice; Microscopy, Fluorescence; Phosphatidylcholines; Spectrometry, Fluorescence | 1985 |
Complexing of heparin with phosphatidylcholine. A possible supramolecular assembly of plasma heparin.
Topics: Chloroform; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Heparin; Humans; Macromolecular Substances; Methanol; Phosphatidylcholines; Solubility; Ultracentrifugation | 1985 |
Determination of the topography of cytochrome b5 in lipid vesicles by fluorescence quenching.
Topics: Calorimetry, Differential Scanning; Cytochrome b Group; Cytochromes b5; Kinetics; Liposomes; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Structure-Activity Relationship | 1985 |
A calorimetry and deuterium NMR study of mixed model membranes of 1-palmitoyl-2-oleylphosphatidylcholine and saturated phosphatidylcholines.
Topics: Calorimetry, Differential Scanning; Deuterium; Magnetic Resonance Spectroscopy; Mathematics; Membranes, Artificial; Phosphatidylcholines | 1985 |
Measurement of phospholipase A2 activity in human endometrium during the menstrual cycle.
Topics: Adult; Calcium; Endometrium; Female; Humans; Hydrogen-Ion Concentration; Menstrual Cycle; Middle Aged; Oleic Acid; Oleic Acids; Phosphatidylcholines; Phospholipases; Phospholipases A; Phospholipases A2 | 1985 |
Miscibility, chain packing, and hydration of 1-palmitoyl-2-oleoyl phosphatidylcholine and other lipids in surface phases.
Topics: Glycerides; Liposomes; Oleic Acids; Phosphatidylcholines; Solubility; Structure-Activity Relationship; Surface Properties | 1985 |
Cytochrome b5 induced flip-flop of phospholipids in sonicated vesicles.
Topics: Animals; Cattle; Cytochrome b Group; Cytochromes b5; Indicators and Reagents; Kinetics; Lipid Bilayers; Liver; Male; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; Structure-Activity Relationship | 1985 |
Lipid solvation of cytochrome c oxidase. Deuterium, nitrogen-14, and phosphorus-31 nuclear magnetic resonance studies on the phosphocholine head group and on cis-unsaturated fatty acyl chains.
Topics: Animals; Cattle; Deuterium; Electron Transport Complex IV; Fatty Acids, Unsaturated; Lipid Bilayers; Magnetic Resonance Spectroscopy; Nitrogen; Phosphatidylcholines; Phosphorus; Protein Conformation; Thermodynamics | 1983 |
Interaction of adrenocorticotropin-(11-24)-tetradecapeptide with neutral lipid membranes revealed by infrared attenuated total reflection spectroscopy.
Topics: Adrenocorticotropic Hormone; Circular Dichroism; Cosyntropin; Liposomes; Peptide Fragments; Phosphatidylcholines; Protein Conformation; Spectrophotometry, Infrared | 1984 |
Catabolism of phospholipids by chicken seminal components after storage.
Topics: Animals; Calcium; Carbon Radioisotopes; Chickens; Cholic Acid; Cholic Acids; Enzyme Activation; Male; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Phospholipids; Semen; Semen Preservation; Spermatozoa | 1984 |
Ca2+ binding to phosphatidylcholine bilayers as studied by deuterium magnetic resonance. Evidence for the formation of a Ca2+ complex with two phospholipid molecules.
Topics: Calcium; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Sodium Chloride; Spectrophotometry, Atomic | 1984 |
Melittin and a chemically modified trichotoxin form alamethicin-type multi-state pores.
Topics: Alamethicin; Anti-Bacterial Agents; Bee Venoms; Lipid Bilayers; Melitten; Molecular Conformation; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Protein Conformation | 1983 |
Polymorphic phase behaviour of dilinoleoylphosphatidylethanolamine and palmitoyloleoylphosphatidylcholine mixtures. Structural changes between hexagonal, cubic and bilayer phases.
Topics: Freeze Fracturing; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Microscopy, Electron; Models, Biological; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; X-Ray Diffraction | 1983 |
Deuterium nuclear magnetic resonance studies of bile salt/phosphatidylcholine mixed micelles.
Topics: Deoxycholic Acid; Humans; Lipid Bilayers; Magnetic Resonance Spectroscopy; Micelles; Models, Biological; Molecular Conformation; Phosphatidylcholines | 1983 |
Transfer of polycyclic aromatic hydrocarbons between model membranes: relation to carcinogenicity.
Topics: Biological Transport; Carcinogens, Environmental; Cell Membrane; Cytochrome P-450 Enzyme System; Phosphatidylcholines; Polycyclic Compounds; Solubility; Structure-Activity Relationship; Thermodynamics | 1983 |
Thermal and 13C-NMR study of the dynamic structure of 1-palmitoyl-2-oleyl-sn-glycero-3-phosphocholine and 1-oleyl-2-palmitoyl-sn-glycero-3-phosphocholine in aqueous dispersions.
Topics: Calorimetry, Differential Scanning; Deuterium; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Structure-Activity Relationship; Thermodynamics | 1982 |
Raman spectroscopic study of the interactions of dimyristoyl- and 1-palmitoyl-2-oleoylphosphatidylcholine liposomes with myelin proteolipid apoprotein.
Topics: Apoproteins; Dimyristoylphosphatidylcholine; Liposomes; Myelin Proteins; Phosphatidylcholines; Protein Binding; Proteolipids; Spectrum Analysis, Raman; Temperature | 1980 |
Liposomal cyclosporine. Comparison of drug and lipid carrier pharmacokinetics and biodistribution.
Topics: Animals; Carbon Radioisotopes; Cholesterol; Cyclosporine; Drug Carriers; Female; Kidney; Liposomes; Liver; Lung; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Myocardium; Phosphatidylcholines; Radioisotope Dilution Technique; Spleen; Time Factors; Tissue Distribution | 1995 |
Phosphatidylcholine molecular species of calf lung surfactant.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Cattle; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Fatty Acids; Hydrolysis; Phosphatidylcholines; Phospholipases A; Pulmonary Surfactants | 1995 |
Apolipoprotein A-I conformation in reconstituted discoidal lipoproteins varying in phospholipid and cholesterol content.
Topics: Antibodies, Monoclonal; Apolipoprotein A-I; Binding, Competitive; Cholesterol; Epitopes; Humans; Models, Structural; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary | 1995 |
Fragmentation of phospholipid bilayers by myelin basic protein.
Topics: Calcium; Humans; Kinetics; Lipid Bilayers; Myelin Basic Protein; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Structure-Activity Relationship | 1994 |
The modulation of protein kinase C activity by membrane lipid bilayer structure.
Topics: Animals; Brain; Fluorescent Dyes; Kinetics; Lipid Bilayers; Membrane Fluidity; Micelles; Myelin Basic Protein; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Phosphorylation; Protein Kinase C; Rats; Spectrometry, Fluorescence; Structure-Activity Relationship; X-Ray Diffraction | 1994 |
Structural domain of apolipoprotein A-I involved in its interaction with cells.
Topics: Adipocytes; Antibodies, Monoclonal; Apolipoprotein A-I; Binding Sites; Binding, Competitive; Cholesterol; Epitopes; HeLa Cells; Humans; Phosphatidylcholines | 1994 |
250-GHz electron spin resonance studies of polarity gradients along the aliphatic chains in phospholipid membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Biophysical Phenomena; Biophysics; Electron Spin Resonance Spectroscopy; Gramicidin; Hydrogen Bonding; Membranes, Artificial; Phosphatidylcholines; Phospholipids; Spin Labels; Water | 1994 |
Detection of coexisting fluid phospholipid phases by equilibrium Ca2+ binding: peptide-poor L alpha and peptide-rich HII phase coexistence in gramicidin A'/phospholipid dispersions.
Topics: Binding Sites; Calcium; Chelating Agents; Gramicidin; Kinetics; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylserines; Phosphorus Radioisotopes; Reference Standards; X-Ray Diffraction | 1994 |
A peptide from the heptad repeat of human immunodeficiency virus gp41 shows both membrane binding and coiled-coil formation.
Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Electron Spin Resonance Spectroscopy; HIV Envelope Protein gp41; HIV-1; Humans; Leucine Zippers; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Spin Labels | 1995 |
Cooperativity and binding in the mechanism of cytosolic phospholipase A2.
Topics: Animals; Arachidonic Acid; Baculoviridae; Binding Sites; Calcium; Cytosol; Enzyme Stability; Glycerol; Humans; Kinetics; Liposomes; Mathematics; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Phospholipids; Recombinant Proteins; Spodoptera; Substrate Specificity | 1995 |
Effects of the neutral lipid content of high density lipoprotein on apolipoprotein A-I structure and particle stability.
Topics: Apolipoprotein A-I; Cholesterol Esters; Drug Stability; Electrochemistry; Humans; In Vitro Techniques; Lipids; Lipoproteins, HDL; Microscopy, Electron; Molecular Conformation; Molecular Structure; Phosphatidylcholines; Triolein | 1995 |
Membrane hydration and structure on a subnanometer scale as seen by high resolution solid state nuclear magnetic resonance: POPC and POPC/C12EO4 model membranes.
Topics: Carbon Isotopes; Deuterium; Kinetics; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Biological; Molecular Conformation; Phosphatidylcholines; Polyethylene Glycols; Sensitivity and Specificity; Water | 1995 |
Determination of the pKa of membrane-bound N,N-dimethylsphingosine using deuterium NMR spectroscopy.
Topics: Deuterium; Hydrogen-Ion Concentration; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Protein Kinase C; Sphingosine | 1995 |
Bile acid/phosphatidylcholine interactions in mixed monomolecular layers: differences in condensation effects but not interfacial orientation between hydrophobic and hydrophilic bile acid species.
Topics: Bile Acids and Salts; Cholesterol; Molecular Conformation; Phosphatidylcholines; Surface Properties; Surface-Active Agents | 1995 |
Apolipoprotein A-I conformation in discoidal particles: evidence for alternate structures.
Topics: Antibodies, Monoclonal; Apolipoprotein A-I; Binding Sites, Antibody; Binding, Competitive; Cholesterol; Epitopes; Humans; Lipoproteins, LDL; Liposomes; Models, Structural; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Radioimmunoassay; Reference Values | 1993 |
Do substance P agonists insert into the lipid membrane?
Topics: Animals; Cattle; Cell Membrane; Lipid Bilayers; Liposomes; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Receptors, Neurokinin-1; Spinal Cord; Substance P | 1993 |
Secondary structure and orientation of phospholamban reconstituted in supported bilayers from polarized attenuated total reflection FTIR spectroscopy.
Topics: Amino Acid Sequence; Calcium-Binding Proteins; Dimyristoylphosphatidylcholine; Lipid Bilayers; Mathematics; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Protein Structure, Secondary; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared | 1995 |
Integrated light-scattering spectroscopy, a sensitive probe for peptide-vesicle binding: application to the membrane-bound colicin E1 channel peptide.
Topics: Biophysical Phenomena; Biophysics; Colicins; Light; Liposomes; Models, Chemical; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Scattering, Radiation; Spectrophotometry | 1995 |
Glycosphingolipid acyl chain order profiles: substituent effects.
Topics: Animals; Cattle; Cholesterol; Deuterium; Fatty Acids; Galactosylceramides; Glycosphingolipids; Liposomes; Magnetic Resonance Spectroscopy; Molecular Structure; Phosphatidylcholines; Stearic Acids | 1995 |
Study of vesicle leakage induced by melittin.
Topics: Electrochemistry; Fluoresceins; Liposomes; Melitten; Models, Statistical; Palmitic Acid; Palmitic Acids; Phosphatidylcholines; Phosphatidylglycerols; Spectrometry, Fluorescence; Structure-Activity Relationship | 1995 |
Liquid-crystalline phases of cholesterol/lipid bilayers as revealed by the fluorescence of trans-parinaric acid.
Topics: Biophysical Phenomena; Biophysics; Cholesterol; Dimyristoylphosphatidylcholine; Fatty Acids, Unsaturated; Fluorescence Polarization; Fluorescent Dyes; In Vitro Techniques; Lipid Bilayers; Phosphatidylcholines | 1995 |
Macro-ripple phase formation in bilayers composed of galactosylceramide and phosphatidylcholine.
Topics: Animals; Biophysical Phenomena; Biophysics; Brain Chemistry; Cattle; Freeze Fracturing; Galactosylceramides; In Vitro Techniques; Lipid Bilayers; Macromolecular Substances; Microscopy, Electron; Molecular Structure; Phosphatidylcholines | 1995 |
The effect of albumin on incorporation of merocyanine 540 into phospholipid liposomes.
Topics: Albumins; Animals; Binding Sites; Binding, Competitive; Biophysical Phenomena; Biophysics; Cattle; Fluorescent Dyes; In Vitro Techniques; Liposomes; Phosphatidylcholines; Pyrimidinones; Spectrometry, Fluorescence; Spectrophotometry | 1994 |
In vitro interaction of zinc(II)-phthalocyanine-containing liposomes and plasma lipoproteins.
Topics: Autoradiography; Carbon Radioisotopes; Centrifugation, Density Gradient; Electrophoresis, Agar Gel; Humans; Indoles; Iodine Radioisotopes; Isoindoles; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Liposomes; Organometallic Compounds; Phosphatidylcholines; Zinc Compounds | 1994 |
In vivo turnover of phospholipids in rabbit erythrocytes.
Topics: Animals; Carrier Proteins; Erythrocyte Membrane; Fatty Acids; Female; Half-Life; Membrane Proteins; Phosphatidylcholines; Phospholipid Transfer Proteins; Phospholipids; Rabbits | 1994 |
Mean-field calculations of chain packing and conformational statistics in lipid bilayers: comparison with experiments and molecular dynamics studies.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Biophysical Phenomena; Biophysics; In Vitro Techniques; Lipid Bilayers; Models, Chemical; Molecular Conformation; Molecular Structure; Phosphatidylcholines; Thermodynamics | 1994 |
Translational diffusion of bovine prothrombin fragment 1 weakly bound to supported planar membranes: measurement by total internal reflection with fluorescence pattern photobleaching recovery.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Cattle; Diffusion; Kinetics; Liposomes; Mathematics; Peptide Fragments; Phosphatidylcholines; Phosphatidylserines; Photochemistry; Protein Binding; Protein Precursors; Prothrombin; Spectrometry, Fluorescence; Structure-Activity Relationship | 1994 |
Detection and characterization of the onset of bilayer packing defects by nanosecond-resolved intramolecular excimer fluorescence spectroscopy.
Topics: Kinetics; Lipid Bilayers; Models, Chemical; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; Spectrometry, Fluorescence | 1994 |
Interactions between human defensins and lipid bilayers: evidence for formation of multimeric pores.
Topics: alpha-Defensins; Amino Acid Sequence; Anti-Infective Agents; Blood Proteins; Defensins; Humans; Lipid Bilayers; Membrane Fusion; Models, Molecular; Molecular Sequence Data; Naphthalenes; Neutrophils; Permeability; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Sequence Homology, Amino Acid | 1994 |
Characterization of two membrane-bound forms of OmpA.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Bacterial Outer Membrane Proteins; Bromine; Dimyristoylphosphatidylcholine; Escherichia coli; Lipid Bilayers; Liposomes; Peptide Fragments; Phosphatidylcholines; Protein Folding; Protein Structure, Secondary; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Trypsin | 1995 |
Hydration force parameters of phosphatidylcholine lipid bilayers as determined from 2H-NMR studies of deuterated water.
Topics: Biophysical Phenomena; Biophysics; Deuterium Oxide; In Vitro Techniques; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Chemical; Osmotic Pressure; Phosphatidylcholines; Thermodynamics | 1994 |
Effect of the cholesterol content of reconstituted LpA-I on lecithin:cholesterol acyltransferase activity.
Topics: Apolipoprotein A-I; Cholesterol; Humans; Kinetics; Lipoprotein(a); Lipoproteins, HDL; Lipoproteins, HDL3; Membrane Potentials; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines; Recombinant Proteins; Surface Properties | 1995 |
Phosphorylation reverses the membrane association of peptides that correspond to the basic domains of MARCKS and neuromodulin.
Topics: Amino Acid Sequence; Animals; Cattle; GAP-43 Protein; Intracellular Signaling Peptides and Proteins; Kinetics; Liposomes; Membrane Glycoproteins; Membrane Proteins; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Nerve Tissue Proteins; Peptide Fragments; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Phosphopeptides; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Proteins; Spectrometry, Fluorescence | 1994 |
Effect of ethanol on metarhodopsin II formation is potentiated by phospholipid polyunsaturation.
Topics: Cell Membrane; Diphenylhexatriene; Drug Synergism; Ethanol; Fatty Acids, Unsaturated; Fluorescence Polarization; Liposomes; Membrane Lipids; Phosphatidylcholines; Phospholipids; Rhodopsin; Rod Cell Outer Segment; Thermodynamics | 1994 |
Evidence for the modulation of Pseudomonas aeruginosa exotoxin A-induced pore formation by membrane surface charge density.
Topics: ADP Ribose Transferases; Animals; Bacterial Toxins; Binding Sites; Cell Membrane Permeability; Coated Vesicles; Escherichia coli; Exotoxins; Fluoresceins; Fluorescent Antibody Technique; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Lipid Bilayers; Mice; Models, Biological; Osmolar Concentration; Phosphatidylcholines; Phosphatidylserines; Porosity; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Virulence Factors | 1994 |
Topology of an amphiphilic mitochondrial signal sequence in the membrane-inserted state: a spin labeling study.
Topics: Amino Acid Sequence; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Liposomes; Mitochondria; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Protein Sorting Signals; Protein Structure, Secondary; Saccharomyces cerevisiae; Spin Labels | 1994 |
Distribution of distances between the tryptophan and the N-terminal residue of melittin in its complex with calmodulin, troponin C, and phospholipids.
Topics: Calmodulin; Chemical Phenomena; Chemistry, Physical; Dansyl Compounds; Liposomes; Melitten; Phosphatidylcholines; Phospholipids; Spectrophotometry; Troponin; Troponin C; Tryptophan | 1994 |
Infrared study of the bilayer stability behavior of binary and ternary phospholipid mixtures containing unsaturated phosphatidylethanolamine.
Topics: Lipid Bilayers; Phosphatidylcholines; Phosphatidylethanolamines; Spectrophotometry, Infrared | 1994 |
Measurement of reaction products from hypochlorous acid and unsaturated lipids.
Topics: Cholesterol; Chromatography, Thin Layer; Fatty Acids, Unsaturated; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen Peroxide; Hypochlorous Acid; Micelles; Models, Biological; Neutrophils; Peroxidase; Phosphatidylcholines | 1994 |
Annexin IV reduces the rate of lateral lipid diffusion and changes the fluid phase structure of the lipid bilayer when it binds to negatively charged membranes in the presence of calcium.
Topics: Animals; Annexin A4; Calcium; Cattle; Cell Membrane; Diffusion; Edetic Acid; Electrochemistry; Fluorescent Dyes; Kinetics; Lipid Bilayers; Membrane Lipids; Phosphatidylcholines; Phosphatidylglycerols; Photochemistry; Recombinant Proteins | 1994 |
Dynamic properties of water at phosphatidylcholine lipid-bilayer surfaces as seen by deuterium and pulsed field gradient proton NMR.
Topics: Chemical Phenomena; Chemistry, Physical; Deuterium; Diffusion; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Protons; Thermodynamics; Water | 1994 |
Interactions between soluble sugars and POPC (1-palmitoyl-2-oleoylphosphatidylcholine) during dehydration: vitrification of sugars alters the phase behavior of the phospholipid.
Topics: Calorimetry, Differential Scanning; Carbohydrates; Incineration; Phosphatidylcholines; Water | 1994 |
Interaction between zinc(II)-phthalocyanine-containing liposomes and human low density lipoprotein.
Topics: Carbon Radioisotopes; Chromatography, Affinity; Chromatography, Ion Exchange; Electrophoresis, Agar Gel; Humans; Indoles; Isoindoles; Lipoproteins, LDL; Liposomes; Organometallic Compounds; Phosphatidylcholines; Zinc; Zinc Compounds | 1994 |
Studies on lipid membranes by two-dimensional Fourier transform ESR: Enhancement of resolution to ordering and dynamics.
Topics: Computer Simulation; Electron Spin Resonance Spectroscopy; Fourier Analysis; In Vitro Techniques; Membrane Lipids; Models, Chemical; Phosphatidylcholines; Spin Labels; Thermodynamics | 1994 |
An electron spin resonance study of interactions between phosphatidylcholine and phosphatidylserine in oriented membranes.
Topics: Biophysical Phenomena; Biophysics; Electron Spin Resonance Spectroscopy; In Vitro Techniques; Lipid Bilayers; Membrane Lipids; Molecular Conformation; Molecular Structure; Phosphatidylcholines; Phosphatidylserines; Spin Labels; Thermodynamics | 1994 |
Ca2+ transport properties of ionophores A23187, ionomycin, and 4-BrA23187 in a well defined model system.
Topics: Biophysical Phenomena; Biophysics; Calcimycin; Calcium; Electrochemistry; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Transport; Ionomycin; Kinetics; Liposomes; Membrane Potentials; Models, Biological; Phosphatidylcholines | 1994 |
Effect of ozonation products on phospholipase A2 hydrolytic activity: use of bis(1-hydroxyheptyl)peroxide as a precursor of the ozonation product 1-hydroxy-1-hydroperoxyheptane.
Topics: Alcohols; Hydrolysis; Kinetics; Liposomes; Ozone; Peroxides; Phosphatidylcholines; Phospholipases A; Phospholipases A2 | 1994 |
Identification and characterization of kink motifs in 1-palmitoyl-2-oleoyl- phosphatidylcholines: a molecular mechanics study.
Topics: Calorimetry; Computer Graphics; Isomerism; Lipid Bilayers; Models, Molecular; Molecular Conformation; Phosphatidylcholines | 1994 |
Influence of plasma on the osmotic sensitivity of large unilamellar vesicles prepared by extrusion.
Topics: Blood Physiological Phenomena; Cholesterol; Humans; Liposomes; Osmosis; Phosphatidylcholines | 1994 |
Erythrocyte membrane lateral sterol domains: a dehydroergosterol fluorescence polarization study.
Topics: Cholesterol; Ergosterol; Erythrocyte Membrane; Fluorescence Polarization; Humans; Kinetics; Liposomes; Mathematics; Membrane Lipids; Models, Biological; Phosphatidylcholines; Sterols | 1994 |
Simultaneous measurement of vesicle diffusion coefficients and trapping efficiencies by means of diffusion ordered 2D NMR spectroscopy.
Topics: Chemical Phenomena; Chemistry, Physical; Diffusion; Liposomes; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Sucrose; Water | 1994 |
Binding and state of aggregation of spin-labeled cecropin AD in phospholipid bilayers: effects of surface charge and fatty acyl chain length.
Topics: Amino Acid Sequence; Anti-Infective Agents; Binding Sites; Electrochemistry; Electron Spin Resonance Spectroscopy; Fatty Acids; Hydrogen-Ion Concentration; Insect Hormones; Insect Proteins; Lipid Bilayers; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Spin Labels; Temperature | 1994 |
Langevin dynamics studies of unsaturated phospholipids in a membrane environment.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Algorithms; Biophysical Phenomena; Biophysics; Computer Simulation; Magnetic Resonance Spectroscopy; Membranes, Artificial; Models, Chemical; Phosphatidylcholines; Phospholipids; Stereoisomerism; Thermodynamics | 1993 |
Phospholipase A2 activity in endometrium from early pregnant and non-pregnant ewes.
Topics: Animals; Arachidonic Acid; Cytosol; Dinoprost; Endometrium; Estrus; Female; Kinetics; Oleic Acid; Oleic Acids; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Pregnancy; Pregnancy, Animal; Sheep | 1993 |
Lipid clustering in bilayers detected by the fluorescence kinetics and anisotropy of trans-parinaric acid.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Biophysical Phenomena; Biophysics; Dimyristoylphosphatidylcholine; Fatty Acids, Unsaturated; Fluorescence Polarization; Fluorescent Dyes; Kinetics; Lipid Bilayers; Phosphatidylcholines; Solvents | 1993 |
Pressure effects on the physical properties of lipid bilayers detected by trans-parinaric acid fluorescence decay.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Biophysical Phenomena; Biophysics; Dimyristoylphosphatidylcholine; Diphenylhexatriene; Fatty Acids, Unsaturated; Fluorescence Polarization; Fluorescent Dyes; Hydrostatic Pressure; Lipid Bilayers; Models, Chemical; Molecular Structure; Phosphatidylcholines; Viscosity | 1993 |
Acyl chain orientational order in large unilamellar vesicles: comparison with multilamellar liposomes: a 2H and 31P nuclear magnetic resonance study.
Topics: Biophysical Phenomena; Biophysics; Glycerol; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Molecular Structure; Phosphatidylcholines | 1993 |
Partition coefficients of drugs in bilayer lipid membranes.
Topics: Aspirin; Caffeine; Lipid Bilayers; Phosphatidylcholines; Refractometry; Solubility | 1993 |
Structural and functional domains of apolipoprotein A-I within high density lipoproteins.
Topics: Antibodies, Monoclonal; Apolipoprotein A-I; Binding Sites; Chromatography, Ion Exchange; Endopeptidases; Humans; Immunoblotting; Lipoproteins, HDL; Molecular Weight; Peptide Fragments; Phosphatidylcholines; Substrate Specificity | 1993 |
Resolving the two monolayers of a lipid bilayer in giant unilamellar vesicles using deuterium nuclear magnetic resonance.
Topics: Cholesterol; Deuterium; Freeze Fracturing; Light; Lipid Bilayers; Magnetic Resonance Spectroscopy; Microscopy, Electron; Models, Biological; Phosphatidylcholines; Phosphatidylglycerols; Scattering, Radiation | 1993 |
Direct evidence for the partial dehydration of phosphatidylethanolamine bilayers on approaching the hexagonal phase.
Topics: Desiccation; Humidity; Lipid Bilayers; Mathematics; Models, Theoretical; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; X-Ray Diffraction | 1993 |
Squalene promotes the formation of non-bilayer structures in phospholipid model membranes.
Topics: Calorimetry, Differential Scanning; Liposomes; Membranes; Models, Biological; Phosphatidylcholines; Phospholipids; Squalene; Temperature; Thermodynamics; X-Ray Diffraction | 1993 |
Influence of lipid lateral distribution on the surface charge response of the phosphatidylcholine headgroup as detected using 2H nuclear magnetic resonance.
Topics: Aniline Compounds; Calorimetry, Differential Scanning; Deuterium; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Temperature | 1993 |
Binding of the calcium antagonist flunarizine to phosphatidylcholine bilayers: charge effects and thermodynamics.
Topics: Calorimetry; Cations; Electrochemistry; Flunarizine; Lipid Bilayers; Phosphatidylcholines; Thermodynamics | 1993 |
Effect of high pressure on the association of melittin to membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Dimyristoylphosphatidylcholine; Kinetics; Liposomes; Melitten; Osmolar Concentration; Phosphatidylcholines; Pressure; Protein Binding; Spectrometry, Fluorescence; Structure-Activity Relationship; Thermodynamics | 1993 |
Membrane partitioning: distinguishing bilayer effects from the hydrophobic effect.
Topics: Chromatography, High Pressure Liquid; Indoles; Lipid Bilayers; Liposomes; Mathematics; Models, Biological; Phosphatidylcholines; Skatole; Thermodynamics; Water | 1993 |
Glycosphingolipid headgroup orientation in fluid phospholipid/cholesterol membranes: similarity for a range of glycolipid fatty acids.
Topics: Cell Membrane; Cholesterol; Deuterium; Fatty Acids; Galactosylceramides; Glycolipids; Liposomes; Magnetic Resonance Spectroscopy; Membrane Lipids; Models, Biological; Molecular Conformation; Molecular Structure; Phosphatidylcholines; Structure-Activity Relationship | 1995 |
The action of hypochlorous acid on phosphatidylcholine liposomes in dependence on the content of double bonds. Stoichiometry and NMR analysis.
Topics: Chemical Phenomena; Chemistry, Physical; Dimyristoylphosphatidylcholine; Hypochlorous Acid; Linoleic Acid; Linoleic Acids; Liposomes; Luminescent Measurements; Magnetic Resonance Spectroscopy; Oleic Acid; Oleic Acids; Phosphatidylcholines | 1995 |
Membrane thinning caused by magainin 2.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Circular Dichroism; Crystallography, X-Ray; In Vitro Techniques; Lipid Bilayers; Magainins; Membrane Lipids; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylserines; Xenopus laevis; Xenopus Proteins | 1995 |
Effects of chain unsaturation on the equation of state for lipid monolayers at the air-water interface.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Air; Biophysical Phenomena; Biophysics; In Vitro Techniques; Lipids; Models, Chemical; Molecular Conformation; Molecular Structure; Phosphatidylcholines; Phosphatidylethanolamines; Thermodynamics; Water | 1995 |
Effect of lipid ozonation products on liposomal membranes detected by Laurdan fluorescence.
Topics: Liposomes; Molecular Structure; Ozone; Phosphatidylcholines; Spectrometry, Fluorescence; Structure-Activity Relationship | 1995 |
Lipid vesicle adsorption versus formation of planar bilayers on solid surfaces.
Topics: Adsorption; Diffusion; Escherichia coli; Lipid Bilayers; Membrane Fusion; Phosphatidylcholines; Phospholipids; Sulfates; Surface Properties | 1995 |
High-pressure proton NMR study of lateral self-diffusion of phosphatidylcholines in sonicated unilamellar vesicles.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Diffusion; Gels; Liposomes; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phospholipids; Pressure; Temperature | 1995 |
Thermodynamics of the membrane insertion process of the M13 procoat protein, a lipid bilayer traversing protein containing a leader sequence.
Topics: Amino Acid Sequence; Bacteriophage M13; Biological Transport; Capsid; Capsid Proteins; Energy Transfer; Lipid Bilayers; Membrane Proteins; Models, Chemical; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Conformation; Protein Precursors; Protein Sorting Signals; Spectrometry, Fluorescence; Thermodynamics | 1996 |
Microscale synthesis of phosphatidyl-[3H]choline from 1,2-diacylglycerol. Assessment of isomerization by reversed-phase high-performance liquid chromatography.
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diglycerides; Phosphatidylcholines; Reference Standards; Stereoisomerism | 1995 |
Covalent attachment of functionalized lipid bilayers to planar waveguides for measuring protein binding to biomimetic membranes.
Topics: Acylation; Amino Acid Sequence; Antibodies; Bacterial Proteins; Cross-Linking Reagents; Cysteine; Glass; Lipid Bilayers; Maleimides; Membranes, Artificial; Models, Molecular; Molecular Sequence Data; Optics and Photonics; Peptides; Phosphatidylcholines; Phospholipids; Proteins; Silanes; Streptavidin; Sulfhydryl Compounds | 1995 |
Effects of pH conditions on Ca2+ transport catalyzed by ionophores A23187, 4-BrA23187, and ionomycin suggest problems with common applications of these compounds in biological systems.
Topics: Aminoquinolines; Biological Transport; Calcimycin; Calcium; Fluoresceins; Ionomycin; Ionophores; Kinetics; Liposomes; Membrane Potentials; Models, Biological; Nigericin; Osmolar Concentration; Phosphatidylcholines; Structure-Activity Relationship; Valinomycin | 1995 |
Imaging of single molecule diffusion.
Topics: Fluorescent Dyes; Liposomes; Microscopy, Fluorescence; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; Rhodamines; Sensitivity and Specificity | 1996 |
Effect of cholesterol on the tight insertion of cytochrome b5 into large unilamellar vesicles.
Topics: Centrifugation, Density Gradient; Cholesterol; Chromatography, Gel; Cytochromes b5; Kinetics; Liposomes; Particle Size; Phosphatidylcholines | 1996 |
Roles of surface hydrophobic residues in the interfacial catalysis of bovine pancreatic phospholipase A2.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Catalysis; Cattle; Circular Dichroism; Cloning, Molecular; Escherichia coli; Kinetics; Models, Molecular; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Pancreas; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Protein Conformation; Recombinant Proteins; Surface Properties; Thermodynamics | 1996 |
Pore formation induced by the peptide melittin in different lipid vesicle membranes.
Topics: Amino Acid Sequence; Cell Membrane; Dextrans; Fluorescein-5-isothiocyanate; Fluoresceins; Light; Liposomes; Melitten; Membrane Fusion; Membrane Lipids; Membranes, Artificial; Molecular Sequence Data; Phosphatidylcholines; Scattering, Radiation | 1996 |
Correlation between lipid plane curvature and lipid chain order.
Topics: Biophysical Phenomena; Biophysics; Deuterium; In Vitro Techniques; Magnetic Resonance Spectroscopy; Membrane Lipids; Membranes, Artificial; Molecular Structure; Phosphatidylcholines; Phosphatidylethanolamines; Temperature; Thermodynamics | 1996 |
The effects of cholesterol inclusion on the vesicular membranes of cationic lipids.
Topics: Cations; Chemical Phenomena; Chemistry, Physical; Cholesterol; Diphenylhexatriene; Fluorescence Polarization; Hydrogen Bonding; Lipids; Liposomes; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Phosphatidylcholines | 1996 |
Binding of hisactophilin I and II to lipid membranes is controlled by a pH-dependent myristoyl-histidine switch.
Topics: Animals; Binding Sites; Calorimetry; Carrier Proteins; Circular Dichroism; Dictyostelium; Fatty Acids, Monounsaturated; Fungal Proteins; Histidine; Hydrogen-Ion Concentration; Liposomes; Microfilament Proteins; Models, Molecular; Phosphatidylcholines; Phospholipids; Protein Structure, Secondary; Protozoan Proteins; Surface Properties; Thermodynamics | 1996 |
Design of membrane-inserting peptides: spectroscopic characterization with and without lipid bilayers.
Topics: Amino Acid Sequence; Circular Dichroism; Kinetics; Lipid Bilayers; Liposomes; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Temperature | 1996 |
Osmotic and pH transmembrane gradients control the lytic power of melittin.
Topics: Biophysical Phenomena; Biophysics; Cholesterol; Electrochemistry; Fluoresceins; Hydrogen-Ion Concentration; In Vitro Techniques; Melitten; Membranes, Artificial; Osmolar Concentration; Osmosis; Osmotic Pressure; Permeability; Phosphatidylcholines | 1996 |
Effects of prenatal treatment with betamethasone, L-carnitine, or betamethasone-L-carnitine combinations on the phosphatidylcholine content and composition of the foetal and maternal rat lung.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Betamethasone; Carnitine; Drug Interactions; Female; Fetus; Glucocorticoids; Lung; Phosphatidylcholines; Pregnancy; Rats; Rats, Wistar | 1996 |
Microinjection into giant vesicles and light microscopy investigation of enzyme-mediated vesicle transformations.
Topics: Microinjections; Microscopy; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Snake Venoms | 1996 |
Specific phospholipid association with apolipoprotein A-I stimulates cholesterol efflux from human fibroblasts. Studies with reconstituted sonicated lipoproteins.
Topics: Apolipoprotein A-I; Cells, Cultured; Cholesterol; Cholesterol Esters; Fibroblasts; Humans; Kinetics; Phosphatidylcholines; Phosphatidylinositols; Phospholipids; Skin; Sphingomyelins; Structure-Activity Relationship; Triolein; Ultrasonics | 1996 |
A 1H nuclear magnetic resonance method for investigating the phospholipase D-catalyzed hydrolysis of phosphatidylcholine in liposomes.
Topics: Choline; Fluorescent Dyes; Hydrolysis; Kinetics; Liposomes; Magnetic Resonance Spectroscopy; Microscopy, Electron; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Scattering, Radiation; Streptomyces; Time Factors; Xanthenes | 1996 |
Transmembrane region of the epidermal growth factor receptor: behavior and interactions via 2H NMR.
Topics: Amino Acid Sequence; Cholesterol; Deuterium; Dimyristoylphosphatidylcholine; ErbB Receptors; Humans; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Phosphatidylcholines; Protein Conformation; Temperature; Trifluoroethanol | 1996 |
A slight asymmetry in the transbilayer distribution of lysophosphatidylcholine alters the surface properties and poly(ethylene glycol)-mediated fusion of dipalmitoylphosphatidylcholine large unilamellar vesicles.
Topics: 1,2-Dipalmitoylphosphatidylcholine; 4-Chloro-7-nitrobenzofurazan; Chromatography, Gel; Diphenylhexatriene; Fluorescence Polarization; Fluorescent Dyes; Lipid Bilayers; Liposomes; Lysophosphatidylcholines; Membrane Fusion; Osmotic Pressure; Phosphatidylcholines; Polyethylene Glycols; Serum Albumin, Bovine; Surface Properties; Temperature | 1996 |
Physical effects of biologically formed cholesterol oxidation products on lipid membranes investigated with fluorescence depolarization spectroscopy and electron spin resonance.
Topics: Cholesterol; Cholesterol, LDL; Electron Spin Resonance Spectroscopy; Fluorescence Polarization; Hydroxycholesterols; Lipid Bilayers; Oxidation-Reduction; Phosphatidylcholines; Spectrometry, Fluorescence | 1996 |
Binding of small basic peptides to membranes containing acidic lipids: theoretical models and experimental results.
Topics: Amino Acid Sequence; Calorimetry; Electrochemistry; Lipid Bilayers; Lysine; Models, Molecular; Models, Theoretical; Molecular Conformation; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Protein Binding; Thermodynamics | 1996 |
Surface potentials measure ion concentrations near lipid bilayers during rapid solution changes.
Topics: Animals; Calcium; Calcium Channels; Cesium; Heart; Kinetics; Lipid Bilayers; Membrane Potentials; Models, Biological; Muscle Proteins; Muscle, Skeletal; Patch-Clamp Techniques; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Rabbits; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sheep; Solutions; Surface Properties | 1996 |
Effects of lutein and cholesterol on alkyl chain bending in lipid bilayers: a pulse electron spin resonance spin labeling study.
Topics: Cholesterol; Dimyristoylphosphatidylcholine; Egg Yolk; Electron Spin Resonance Spectroscopy; Kinetics; Lipid Bilayers; Lutein; Models, Structural; Molecular Conformation; Phosphatidylcholines; Spin Labels; Time Factors | 1996 |
Detection of membrane packing defects by time-resolved fluorescence depolarization.
Topics: Cell Membrane; Diffusion; Kinetics; Lipid Bilayers; Mathematics; Models, Biological; Phosphatidylcholines; Phosphatidylethanolamines; Spectrometry, Fluorescence; Time Factors | 1996 |
New fluorescent octadecapentaenoic acids as probes of lipid membranes and protein-lipid interactions.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Blood Platelets; Calorimetry; Cell Membrane; Dimyristoylphosphatidylcholine; Energy Transfer; Fatty Acids, Unsaturated; Fluorescence Polarization; Fluorescent Dyes; Gels; Gramicidin; Humans; Isomerism; Kinetics; Lipid Bilayers; Liposomes; Molecular Conformation; Phosphatidylcholines; Protein Binding; Protein Structure, Secondary; Proteins; Spectrometry, Fluorescence; Tryptophan; Ultrasonography | 1996 |
Sphingolipid-derived signalling modulators: interaction with phosphatidylserine.
Topics: Cholesterol; Deuterium; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Theoretical; Molecular Conformation; Phosphatidylcholines; Phosphatidylserines; Signal Transduction; Sphingolipids; Structure-Activity Relationship | 1996 |
Comparison of the structural and functional effects of monomeric and dimeric human apolipoprotein A-II in high density lipoprotein particles.
Topics: Animals; Apolipoprotein A-II; Biological Transport, Active; Cell Line; Cholesterol; Dimerization; Disulfides; Drug Stability; Humans; In Vitro Techniques; Kinetics; Lipoproteins, HDL; Molecular Structure; Oxidation-Reduction; Phosphatidylcholines; Protein Binding; Protein Conformation; Protein Structure, Secondary; Rats | 1996 |
Effect of cholesterol and charge on pore formation in bilayer vesicles by a pH-sensitive peptide.
Topics: Amino Acid Sequence; Cholesterol; Dextrans; Hydrogen-Ion Concentration; Kinetics; Lipid Bilayers; Models, Biological; Models, Theoretical; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Protein Structure, Secondary | 1996 |
DNA-induced lateral segregation of cationic amphiphiles in lipid bilayer membranes as detected via 2H NMR.
Topics: Cations; Cetrimonium; Cetrimonium Compounds; Cholesterol; DNA; Lipid Bilayers; Magnetic Resonance Spectroscopy; Oleic Acids; Phosphatidylcholines; Poly A; Propylamines | 1996 |
Truncation of the amino terminus of human apolipoprotein A-I substantially alters only the lipid-free conformation.
Topics: Anilino Naphthalenesulfonates; Apolipoprotein A-I; Binding Sites; Calorimetry; Circular Dichroism; Cloning, Molecular; DNA Primers; Escherichia coli; Fluorescent Dyes; Humans; Kinetics; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines; Polymerase Chain Reaction; Protein Conformation; Protein Denaturation; Protein Folding; Recombinant Proteins; Sequence Deletion; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity; Thermodynamics | 1997 |
Salt-triggered intermembrane exchange of phospholipids and hemifusion by myelin basic protein.
Topics: Anions; Binding Sites; Cations; Energy Transfer; Fluorescent Dyes; Glycerophospholipids; Humans; Infant; Lipid Bilayers; Membrane Fusion; Myelin Basic Protein; Particle Size; Phosphatidic Acids; Phosphatidylcholines; Phospholipids; Potassium Chloride; Rhodamines; Spectrometry, Fluorescence; Water | 1997 |
Octyl-beta-D-glucopyranoside partitioning into lipid bilayers: thermodynamics of binding and structural changes of the bilayer.
Topics: Calorimetry; Chemical Phenomena; Chemistry, Physical; Cholesterol; Deuterium; Glucosides; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Models, Molecular; Phosphatidylcholines; Polyethylene Glycols; Temperature; Thermodynamics | 1997 |
Sizing membrane pores in lipid vesicles by leakage of co-encapsulated markers: pore formation by melittin.
Topics: Chromatography, Gel; Dextrans; Drug Compounding; Fluoresceins; Fluorescent Dyes; Liposomes; Melitten; Octoxynol; Particle Size; Permeability; Phosphatidylcholines; Spectrometry, Fluorescence | 1997 |
pH-induced destabilization of lipid bilayers by a lipopeptide derived from influenza hemagglutinin.
Topics: Amino Acid Sequence; Cholesterol; Erythrocyte Membrane; Hemagglutinin Glycoproteins, Influenza Virus; Hydrogen-Ion Concentration; Lipid Bilayers; Lipoproteins; Liposomes; Membrane Fusion; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Solubility | 1997 |
Synergism between mellitin and phospholipase A2 from bee venom: apparent activation by intervesicle exchange of phospholipids.
Topics: Acrylamide; Acrylamides; Amino Acid Sequence; Animals; Bee Venoms; Dithionite; Drug Synergism; Fatty Acids; Fluorescent Dyes; Glycerophospholipids; Hydrolysis; Kinetics; Liposomes; Lysophosphatidylcholines; Melitten; Molecular Sequence Data; Pancreas; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Phospholipids; Pyrenes; Scattering, Radiation; Spectrometry, Fluorescence; Swine | 1997 |
Investigating synthetic P-regions from voltage-gated sodium channel at the conformational and functional levels.
Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Circular Dichroism; Electrophorus; Ion Channel Gating; Lipid Bilayers; Membrane Potentials; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Phosphatidylethanolamines; Protein Conformation; Protein Structure, Secondary; Sodium Channels | 1997 |
Effect of hydrostatic pressure on water penetration and rotational dynamics in phospholipid-cholesterol bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Diphenylhexatriene; Fluorescent Dyes; Kinetics; Lipid Bilayers; Molecular Conformation; Phosphatidylcholines; Rotation; Spectrometry, Fluorescence; Structure-Activity Relationship; Time Factors | 1997 |
Investigation of membrane disruption in the reaction catalyzed by cholesterol oxidase.
Topics: Animals; Binding Sites; Cholesterol Oxidase; Coleoptera; Lipid Bilayers; Mutation; Permeability; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Protein Binding | 1997 |
Cholesterol in condensed and fluid phosphatidylcholine monolayers studied by epifluorescence microscopy.
Topics: 1,2-Dipalmitoylphosphatidylcholine; 4-Chloro-7-nitrobenzofurazan; Animals; Biophysical Phenomena; Biophysics; Cholesterol; Fluorescent Dyes; In Vitro Techniques; Membrane Lipids; Microscopy, Fluorescence; Phosphatidylcholines; Pressure; Surface Properties | 1997 |
Adsorption of bovine prothrombin to spread phospholipid monolayers.
Topics: Adsorption; Animals; Biophysical Phenomena; Biophysics; Calcium; Cattle; In Vitro Techniques; Membranes, Artificial; Microscopy, Fluorescence; Models, Chemical; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Pressure; Prothrombin; Surface Properties | 1997 |
Alzheimer's disease amyloid beta peptide 25-35 inhibits lipid peroxidation as a result of its membrane interactions.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Antioxidants; Humans; In Vitro Techniques; Lipid Bilayers; Lipid Peroxidation; Membrane Lipids; Molecular Structure; Peptide Fragments; Phosphatidylcholines | 1997 |
Effect of the N-terminal glycine on the secondary structure, orientation, and interaction of the influenza hemagglutinin fusion peptide with lipid bilayers.
Topics: Amino Acid Sequence; Circular Dichroism; Dimyristoylphosphatidylcholine; Glycine; Hemagglutinin Glycoproteins, Influenza Virus; Influenza A virus; Lipid Bilayers; Membrane Fusion; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Protein Structure, Secondary; Spectrometry, Fluorescence; Tryptophan | 1996 |
Combination of antitumor ether lipid with lipids of complementary molecular shape reduces its hemolytic activity.
Topics: Antineoplastic Agents; Lipids; Liposomes; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipid Ethers | 1997 |
Single-molecule microscopy on model membranes reveals anomalous diffusion.
Topics: Diffusion; Dimyristoylphosphatidylcholine; Fluorescent Dyes; Kinetics; Lipid Bilayers; Liposomes; Microscopy, Fluorescence; Models, Chemical; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; Rhodamines; Sensitivity and Specificity | 1997 |
Quartz crystal microbalance investigation of the interaction of bacterial toxins with ganglioside containing solid supported membranes.
Topics: Cholera Toxin; Electric Impedance; Gangliosides; Gold; Lipid Bilayers; Membranes, Artificial; Pertussis Toxin; Phosphatidylcholines; Quartz; Spectrum Analysis; Tetanus Toxin; Virulence Factors, Bordetella | 1997 |
Gramicidin channels in phospholipid bilayers with unsaturated acyl chains.
Topics: Alkanes; Amino Acid Sequence; Fatty Acids, Unsaturated; Gramicidin; Ion Channels; Lipid Bilayers; Models, Biological; Models, Structural; Molecular Sequence Data; Phosphatidylcholines; Protein Structure, Secondary; Structure-Activity Relationship | 1997 |
Influence of the angle subtended by the positively charged helix face on the membrane activity of amphipathic, antibacterial peptides.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Calorimetry, Differential Scanning; Circular Dichroism; Fluoresceins; Liposomes; Models, Structural; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary | 1997 |
Evidence for superlattice arrangements in fluid phosphatidylcholine/phosphatidylethanolamine bilayers.
Topics: Biophysical Phenomena; Biophysics; In Vitro Techniques; Lipid Bilayers; Macromolecular Substances; Models, Molecular; Phosphatidylcholines; Phosphatidylethanolamines; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared | 1997 |
Domains in cationic lipid plus polyelectrolyte bilayer membranes: detection and characterization via 2H nuclear magnetic resonance.
Topics: Acrylates; Anions; Cations; Electrolytes; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Chemical; Oleic Acids; Phosphatidylcholines; Polystyrenes; Propylamines; Sodium Glutamate; Surface-Active Agents | 1997 |
Entrapment of nucleic acids in liposomes.
Topics: Adenosine Triphosphate; Circular Dichroism; Deoxyribonuclease I; DNA; Drug Compounding; Electrophoresis, Polyacrylamide Gel; Exodeoxyribonucleases; Freeze Fracturing; Liposomes; Microscopy, Electron; Molecular Conformation; Particle Size; Phosphatidylcholines; Phosphatidylserines; Quaternary Ammonium Compounds; RNA, Transfer; Sodium Chloride; Spectrophotometry; Ultrafiltration | 1997 |
Predicting the structure of apolipoprotein A-I in reconstituted high-density lipoprotein disks.
Topics: Amino Acid Sequence; Apolipoprotein A-I; Computer Simulation; Lipid Bilayers; Lipoproteins, HDL; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Sequence Alignment; Water | 1997 |
Interaction of octyl-beta-thioglucopyranoside with lipid membranes.
Topics: Calorimetry; Cholesterol; Detergents; Glucosides; Light; Liposomes; Membrane Lipids; Micelles; Phosphatidylcholines; Phospholipids; Scattering, Radiation; Temperature; Thermodynamics; Thioglucosides | 1997 |
Water translational motion at the bilayer interface: an NMR relaxation dispersion measurement.
Topics: Cyclic N-Oxides; Diffusion; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Magnetic Resonance Spectroscopy; Nitrogen Oxides; Phosphatidylcholines; Spin Labels; Surface Properties; Temperature; Water | 1997 |
Interaction of a highly potent dimeric enkephalin analog, biphalin, with model membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Amino Acid Sequence; Analgesics; Blood-Brain Barrier; Calorimetry, Differential Scanning; Dimerization; Enkephalin, Leucine; Enkephalins; Hydrogen-Ion Concentration; Kinetics; Liposomes; Models, Biological; Permeability; Phosphatidylcholines; Phosphatidylethanolamines; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1997 |
Interaction of class A amphipathic helical peptides with phospholipid unilamellar vesicles.
Topics: Calorimetry; Circular Dichroism; Lipid Bilayers; Liposomes; Peptides; Phosphatidylcholines; Protein Binding; Protein Structure, Secondary; Spectrometry, Fluorescence; Temperature; Thermodynamics; Tryptophan | 1997 |
Effect of vesicle size on their interaction with class A amphipathic helical peptides.
Topics: Acrylamide; Acrylamides; Apolipoproteins; Calorimetry; Lipid Bilayers; Lipoproteins; Liposomes; Particle Size; Peptides; Phosphatidylcholines; Protein Binding; Protein Structure, Secondary; Spectrometry, Fluorescence; Thermodynamics | 1997 |
Annexin V and vesicle membrane electroporation.
Topics: Adsorption; Annexin A5; Diphenylhexatriene; Elasticity; Electroporation; Kinetics; Liposomes; Models, Theoretical; Phosphatidylcholines | 1997 |
Polymerase chain reaction in liposomes.
Topics: Animals; DNA Replication; Drug Stability; Liposomes; Male; Phosphatidylcholines; Phosphatidylserines; Polymerase Chain Reaction; Salmon; Spermatozoa; Temperature; Templates, Genetic | 1995 |
Diacylglycerol is the preferred substrate in high density lipoproteins for human hepatic lipase.
Topics: Carbon Radioisotopes; Diglycerides; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Kinetics; Lipase; Lipoproteins, HDL; Liver; Particle Size; Phosphatidylcholines; Phospholipids; Substrate Specificity; Triolein; Tritium | 1997 |
Interaction of Alzheimer beta-amyloid peptide(1-40) with lipid membranes.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Circular Dichroism; Deuterium; Membranes, Artificial; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphatidylcholines; Phosphatidylglycerols; Phosphorus Isotopes; Protein Binding; Protein Structure, Secondary | 1997 |
Quantitative studies on the melittin-induced leakage mechanism of lipid vesicles.
Topics: Binding Sites; Energy Transfer; Fluoresceins; Fluorescent Dyes; In Vitro Techniques; Kinetics; Liposomes; Melitten; Phosphatidylcholines; Spectrometry, Fluorescence | 1998 |
Molecular organization and dynamics of 1-palmitoyl-2-oleoylphosphatidylcholine bilayers containing a transmembrane alpha-helical peptide.
Topics: Binding Sites; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Membranes, Artificial; Models, Chemical; Molecular Probes; Oxygen; Phosphatidylcholines; Protein Structure, Secondary | 1998 |
Scavenger receptor class B type I as a mediator of cellular cholesterol efflux to lipoproteins and phospholipid acceptors.
Topics: Animals; Arteriosclerosis; CD36 Antigens; Cell Line; Cholesterol; Cricetinae; Humans; Lipoproteins, HDL; Liposomes; Membrane Proteins; Phosphatidylcholines; Phospholipids; Plasma; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class B; Transfection | 1998 |
Conformation of apolipoprotein AI in reconstituted lipoprotein particles and particle-membrane interaction: effect of cholesterol.
Topics: Antibodies, Monoclonal; Apolipoprotein A-I; Binding, Competitive; Cholesterol; Epitopes; Fluorescence; Guanidine; Lipoproteins, HDL; Liposomes; Particle Size; Permeability; Phosphatidylcholines; Picolinic Acids; Protein Conformation; Protein Denaturation; Terbium; Tryptophan | 1998 |
Interactions of arbutin with dry and hydrated bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Arbutin; Calorimetry, Differential Scanning; Carbohydrates; Desiccation; Dimyristoylphosphatidylcholine; Dose-Response Relationship, Drug; Fluorescence; Lipid Bilayers; Phosphatidylcholines; Temperature; Water | 1998 |
Evidence for lipid-dependent structural changes in specific domains of apolipoprotein B100.
Topics: Antibodies, Monoclonal; Apolipoprotein B-100; Apolipoproteins B; Cells, Cultured; Deoxycholic Acid; Dimyristoylphosphatidylcholine; Fibroblasts; Humans; Lipid Metabolism; Lipids; Lipoproteins, LDL; Phosphatidylcholines; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, LDL; Triglycerides | 1998 |
Surface properties of native human plasma lipoproteins and lipoprotein models.
Topics: Animals; Diphenylhexatriene; Elapid Venoms; Elapidae; Emulsions; Fluorescent Dyes; Humans; Lipid Bilayers; Lipolysis; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Protein Conformation; Spectrometry, Fluorescence; Surface Properties; Triolein | 1998 |
Pressure effects on the lateral distribution of cholesterol in lipid bilayers: a time-resolved spectroscopy study.
Topics: Biophysical Phenomena; Biophysics; Cholesterol; Fatty Acids, Unsaturated; Fluorescence Polarization; Fluorescent Dyes; Hydrostatic Pressure; Lipid Bilayers; Phosphatidylcholines; Temperature | 1998 |
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes.
Topics: alpha-Synuclein; Amino Acid Sequence; Animals; Binding Sites; Canaries; Circular Dichroism; Humans; Liposomes; Molecular Sequence Data; Nerve Tissue Proteins; Osmolar Concentration; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Protein Structure, Secondary; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Synucleins | 1998 |
Isolation and properties of a novel phospholipase A from rat brain that hydrolyses fatty acids at sn-1 and sn-2 positions.
Topics: Animals; Brain; Fatty Acids; Hydrolysis; Male; Phosphatidylcholines; Phospholipases A; Phospholipases A1; Phospholipases A2; Rats; Rats, Sprague-Dawley | 1998 |
Interaction of phospholipid vesicles with smooth metal-oxide surfaces.
Topics: Adsorption; Cations, Divalent; Kinetics; Lipid Bilayers; Metals; Optics and Photonics; Oxides; Phosphatidylcholines; Phosphatidylglycerols; Silicon Dioxide; Spectrum Analysis; Surface Properties; Titanium | 1998 |
Dissimilar protection of tocopherol isomers against membrane hydrolysis by phospholipase A2.
Topics: Animals; Cell Membrane; Enzyme Inhibitors; Hydrolysis; In Vitro Techniques; Isomerism; Kinetics; Lipid Bilayers; Pancreas; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Swine; Vitamin E | 1998 |
The EGF receptor transmembrane domain: 2H NMR study of peptide phosphorylation effects in a bilayer environment.
Topics: Amino Acid Sequence; Cell Membrane; Deuterium; ErbB Receptors; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Proteins; Molecular Sequence Data; Peptide Fragments; Peptides; Phosphatidylcholines; Phosphorylation; Protein Structure, Tertiary | 1998 |
Adsorption of vitamin K-dependent blood coagulation proteins to spread phospholipid monolayers as determined from combined measurements of the surface pressure and surface protein concentration.
Topics: Adsorption; Animals; Blood Coagulation Factors; Calcium-Binding Proteins; Cattle; Extracellular Matrix Proteins; Factor IX; Humans; Matrix Gla Protein; Membrane Proteins; Membranes, Artificial; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Pressure; Protein C; Prothrombin; Surface Properties; Vitamin K | 1998 |
Formation of giant liposomes promoted by divalent cations: critical role of electrostatic repulsion.
Topics: Calcium; Cations, Divalent; Glass; Kinetics; Liposomes; Magnesium; Models, Theoretical; Osmolar Concentration; Phosphatidylcholines; Phosphatidylglycerols; Pressure; Static Electricity; Structure-Activity Relationship; Surface Properties | 1998 |
Structural features that modulate the transmembrane migration of a hydrophobic peptide in lipid vesicles.
Topics: Alamethicin; Amino Acid Sequence; Computer Simulation; Kinetics; Liposomes; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphatidylcholines; Protein Conformation; Spin Labels; Time Factors | 1998 |
Lipid ozonation products activate phospholipases A2, C, and D.
Topics: Arachidonic Acid; Bronchi; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Humans; Isoenzymes; Lipids; Oxidants, Photochemical; Ozone; Phosphatidylcholines; Phospholipase D; Phospholipases A; Phospholipases A2; Signal Transduction; Type C Phospholipases | 1998 |
Studies of synthetic peptides of human apolipoprotein A-I containing tandem amphipathic alpha-helixes.
Topics: Apolipoprotein A-I; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Circular Dichroism; Dimyristoylphosphatidylcholine; Humans; Light; Liposomes; Membrane Lipids; Microscopy, Electron; Peptide Fragments; Phosphatidylcholines; Protein Structure, Secondary; Scattering, Radiation | 1998 |
Phospholipid component volumes: determination and application to bilayer structure calculations.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Crystallography; Lipid Bilayers; Models, Chemical; Neutrons; Normal Distribution; Phosphatidylcholines; Scattering, Radiation; Structure-Activity Relationship; X-Ray Diffraction | 1998 |
The reduction in electroporation voltages by the addition of a surfactant to planar lipid bilayers.
Topics: Detergents; Electric Conductivity; Electrochemistry; Electroporation; Kinetics; Lipid Bilayers; Models, Chemical; Phosphatidylcholines; Polyethylene Glycols; Surface-Active Agents; Time Factors | 1998 |
The role of glycolipids in mediating cell adhesion: a flow chamber study.
Topics: Animals; Cell Adhesion; Cell Membrane; Cell Movement; CHO Cells; Cricetinae; Glycolipids; Ligands; Lipid Bilayers; Mice; Microscopy; Microscopy, Fluorescence; Models, Biological; Oligosaccharides; Phosphatidylcholines; Recombinant Proteins; Rheology; Selectins; Sialyl Lewis X Antigen | 1998 |
Lipid and stress dependence of amphotericin B ion selective channels in sterol-free membranes.
Topics: Amphotericin B; Arylsulfonates; Eicosanoic Acids; Electric Conductivity; Fluorescent Dyes; Ion Channels; Lipid Metabolism; Liposomes; Osmotic Pressure; Phosphatidylcholines | 1998 |
Lalpha-phase separation in phosphatidylcholine-water systems induced by alkali chlorides.
Topics: Chemical Phenomena; Chemistry, Physical; Chlorides; Crystallization; Hydrogen-Ion Concentration; Lithium Chloride; Phosphatidylcholines; Scattering, Radiation; Water; X-Rays | 1998 |
Interfacial membrane properties modulate protein kinase C activation: role of the position of acyl chain unsaturation.
Topics: Animals; Binding Sites; Coumarins; Enzyme Activation; Fatty Acids, Unsaturated; Fluorescence Polarization; Fluorescent Dyes; Membrane Lipids; Membrane Proteins; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Protein Kinase C; Rats; Spectrometry, Fluorescence; Surface Properties | 1998 |
Selective separation process of proteins based on the heat stress-induced translocation across phospholipid membranes.
Topics: alpha-Glucosidases; beta-Galactosidase; Biological Transport; Carbonic Anhydrases; Chemistry Techniques, Analytical; Hot Temperature; Liposomes; Phosphatidylcholines | 1998 |
Fourier transform infrared spectroscopy as a probe for the study of the hydration of lipid self-assemblies. I. Methodology and general phenomena.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Adsorption; Humidity; Kinetics; Models, Theoretical; Phosphatidylcholines; Spectroscopy, Fourier Transform Infrared; Water | 1998 |
Fourier transform infrared spectroscopy as a probe for the study of the hydration of lipid self-assemblies. II. Water binding versus phase transitions.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Kinetics; Phosphatidylcholines; Phosphatidylethanolamines; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Thermodynamics; Water | 1998 |
Role of the sterol superlattice in the partitioning of the antifungal drug nystatin into lipid membranes.
Topics: Anti-Bacterial Agents; Antifungal Agents; Cholesterol; Dimyristoylphosphatidylcholine; Ergosterol; Lipid Bilayers; Liposomes; Nystatin; Phosphatidylcholines; Spectrometry, Fluorescence | 1998 |
A carbon-13 nuclear magnetic resonance spectroscopic study of inter-proton pair order parameters: a new approach to study order and dynamics in phospholipid membrane systems.
Topics: Biophysical Phenomena; Biophysics; Carbon Isotopes; Cholesterol; Dimyristoylphosphatidylcholine; Ergosterol; Lanosterol; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Lipids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protons; Thermodynamics | 1998 |
The phase behavior of aqueous dispersions of unsaturated mixtures of diacylglycerols and phospholipids.
Topics: Calorimetry, Differential Scanning; Diglycerides; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylethanolamines; X-Ray Diffraction | 1998 |
Membrane insertion of cytochrome P450 1A2 promoted by anionic phospholipids.
Topics: Animals; Anions; Catalysis; Cytochrome P-450 CYP1A2; Lipid Bilayers; Liposomes; Microsomes, Liver; Phosphatidylcholines; Phospholipids; Protein Binding; Protein Conformation; Rabbits; Spectrometry, Fluorescence | 1998 |
Membrane penetration of cytosolic phospholipase A2 is necessary for its interfacial catalysis and arachidonate specificity.
Topics: Arachidonic Acid; Catalysis; Cytosol; Humans; Lipid Bilayers; Liposomes; Membrane Lipids; Pancreas; Phosphatidylcholines; Phosphatidylglycerols; Phospholipases A; Phospholipases A2; Polymers; Protein Binding; Substrate Specificity | 1998 |
The preference of tryptophan for membrane interfaces.
Topics: Bacterial Outer Membrane Proteins; Lipid Bilayers; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Porins; Receptors, Virus; Static Electricity; Surface Properties; Thermodynamics; Tryptophan; Water | 1998 |
Adsorbed to a rigid substrate, dimyristoylphosphatidylcholine multibilayers attain full hydration in all mesophases.
Topics: Adsorption; Aluminum Silicates; Deuterium Oxide; Dimyristoylphosphatidylcholine; Neutrons; Phosphatidylcholines; Surface Properties; Water | 1998 |
Orientation of anthracyclines in lipid monolayers and planar asymmetrical bilayers: a surface-enhanced resonance Raman scattering study.
Topics: Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Idarubicin; Lipid Bilayers; Molecular Structure; Phosphatidic Acids; Phosphatidylcholines; Phospholipids; Pressure; Scattering, Radiation; Spectrum Analysis, Raman; Surface Properties | 1998 |
Cationic amphiphile interactions with polyadenylic acid as probed via 2H-NMR.
Topics: Acrylic Resins; Binding Sites; Biophysical Phenomena; Biophysics; Cations; Cetrimonium; Cetrimonium Compounds; Cholesterol; Deuterium; Fatty Acids, Monounsaturated; Lipid Bilayers; Magnetic Resonance Spectroscopy; Osmolar Concentration; Phosphatidylcholines; Poly A; Quaternary Ammonium Compounds; Static Electricity | 1998 |
Epidermal growth factor receptor transmembrane domain: 2H NMR implications for orientation and motion in a bilayer environment.
Topics: Alanine; Amino Acid Sequence; Cell Membrane; Cholesterol; ErbB Receptors; Humans; Hydrogen; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary | 1998 |
Safranine-O as membrane potential probe: a mechanistic study using fluorescence spectroscopy.
Topics: Cholesterol; Fluorescent Dyes; Liposomes; Membrane Potentials; Molecular Probes; Phenazines; Phosphatidylcholines; Spectrometry, Fluorescence | 1998 |
Effect of cholesteryl hemisuccinate on the interfacial properties of phosphatidylcholine bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cell Division; Cholesterol Esters; Lipid Bilayers; Phosphatidylcholines | 1998 |
Sphingomyelinase induces lipid microdomain formation in a fluid phosphatidylcholine/sphingomyelin membrane.
Topics: Animals; Cattle; Ceramides; Hydrolysis; Lipid Bilayers; Liposomes; Phosphatidylcholines; Spectrometry, Fluorescence; Sphingomyelin Phosphodiesterase; Sphingomyelins; Sphingosine; Thermodynamics | 1998 |
Alamethicin helices in a bilayer and in solution: molecular dynamics simulations.
Topics: Alamethicin; Amino Acid Sequence; Biophysical Phenomena; Biophysics; Computer Simulation; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Solutions; Thermodynamics | 1999 |
Studies of phospholipid hydration by high-resolution magic-angle spinning nuclear magnetic resonance.
Topics: Biophysical Phenomena; Biophysics; Hydrogen; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Permeability; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Water | 1999 |
Enzymatic reactions in liposomes using the detergent-induced liposome loading method.
Topics: Cholates; Deoxyribonuclease I; Detergents; Glycogen; Liposomes; Macromolecular Substances; Methods; Permeability; Phosphatidylcholines; Phosphorylases | 1999 |
The membrane affinities of the aliphatic amino acid side chains in an alpha-helical context are independent of membrane immersion depth.
Topics: Amino Acid Sequence; Amino Acids; Circular Dichroism; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Membrane Proteins; Molecular Sequence Data; Octanols; Peptide Fragments; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Structure, Secondary; Thermodynamics; Water | 1999 |
A comparative study of the activation of protein kinase C alpha by different diacylglycerol isomers.
Topics: Calcium; Enzyme Activation; Fatty Acids; Glycerol; Isoenzymes; Magnesium; Membranes, Artificial; Octoxynol; Phosphatidylcholines; Phosphatidylserines; Protein Kinase C; Protein Kinase C-alpha; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship | 1999 |
Molecular dynamics on a model for nascent high-density lipoprotein: role of salt bridges.
Topics: Apolipoprotein A-I; Biophysical Phenomena; Biophysics; Computer Simulation; Lipoproteins, HDL; Membrane Lipids; Models, Molecular; Peptides; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Salts; Thermodynamics | 1999 |
Apolipoprotein A-I charge and conformation regulate the clearance of reconstituted high density lipoprotein in vivo.
Topics: Apolipoprotein A-I; Apolipoprotein A-II; Humans; Lipoprotein(a); Lipoproteins, HDL; Lipoproteins, HDL3; Molecular Conformation; Phosphatidylcholines; Static Electricity | 1999 |
An alamethicin channel in a lipid bilayer: molecular dynamics simulations.
Topics: Alamethicin; Amino Acid Sequence; Biophysical Phenomena; Biophysics; Computer Simulation; Ion Channels; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Thermodynamics; Water | 1999 |
Orientation of the pore-forming peptide GALA in POPC vesicles determined by a BODIPY-avidin/biotin binding assay.
Topics: Amino Acid Sequence; Avidin; Biophysical Phenomena; Biophysics; Biotin; Boron Compounds; Fluorescent Dyes; Hydrogen-Ion Concentration; Lipid Bilayers; Liposomes; Peptides; Phosphatidylcholines; Protein Binding | 1999 |
Bilayer permeability-based substrate selectivity of an enzyme in liposomes.
Topics: Biotechnology; Caseins; Chymotrypsin; Enzyme Stability; Enzymes, Immobilized; In Vitro Techniques; Kinetics; Lipid Bilayers; Liposomes; Permeability; Phosphatidylcholines; Substrate Specificity | 1998 |
A "release" protocol for isothermal titration calorimetry.
Topics: Biophysical Phenomena; Biophysics; Calorimetry; Ligands; Lipid Bilayers; Permeability; Phosphatidylcholines; Thermodynamics | 1999 |
The effects of gramicidin on electroporation of lipid bilayers.
Topics: Biophysical Phenomena; Biophysics; Dimerization; Electric Conductivity; Electrochemistry; Electroporation; Gramicidin; Lipid Bilayers; Phosphatidylcholines | 1999 |
Polymorphism and interactions of a viral fusion peptide in a compressed lipid monolayer.
Topics: Amino Acid Sequence; Biophysical Phenomena; Biophysics; HIV Envelope Protein gp41; HIV-1; Membrane Fusion; Membrane Lipids; Models, Chemical; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Polymorphism, Genetic; Surface Properties; Viral Fusion Proteins | 1999 |
Direct, ultrasensitive, and selective optical detection of protein toxins using multivalent interactions.
Topics: Albumins; Binding Sites; Boron Compounds; Cholera Toxin; Contrast Media; Energy Transfer; Fluorescein; Fluorescent Dyes; G(M1) Ganglioside; Lipid Bilayers; Membranes, Artificial; Optics and Photonics; Phosphatidylcholines; Proteins; Sensitivity and Specificity; Signal Transduction; Spectrometry, Fluorescence; Toxins, Biological | 1999 |
A dual-probe fluorescence method to examine selective perturbations of membrane permeability by melittin.
Topics: Cell Membrane Permeability; Cholesterol; Fluoresceins; Fluorescent Dyes; Lipid Bilayers; Liposomes; Melitten; Phosphatidylcholines; Rhodamines; Spectrometry, Fluorescence | 1999 |
Molecular determinants of the reversible membrane anchorage of the G-protein transducin.
Topics: Animals; Cations, Divalent; Cattle; Circular Dichroism; Hydrogen-Ion Concentration; Membrane Lipids; Membrane Proteins; Models, Molecular; Myristic Acid; Osmolar Concentration; Phosphatidylcholines; Phosphatidylglycerols; Pressure; Protein Binding; Protein Prenylation; Protein Structure, Secondary; Solutions; Static Electricity; Transducin | 1999 |
Protein expression in liposomes.
Topics: Animals; Bioreactors; Biotechnology; Cell Compartmentation; In Vitro Techniques; Liposomes; Models, Biological; Origin of Life; Peptides; Phosphatidylcholines; Protein Biosynthesis; Proteins; Ribosomes; RNA, Transfer, Amino Acyl | 1999 |
Binding of antibacterial magainin peptides to electrically neutral membranes: thermodynamics and structure.
Topics: Amino Acid Sequence; Animals; Anti-Infective Agents; Antimicrobial Cationic Peptides; Calorimetry; Cholesterol; Lipid Bilayers; Magainins; Molecular Sequence Data; Peptides; Permeability; Phosphatidylcholines; Protein Binding; Protein Conformation; Protein Structure, Secondary; Static Electricity; Thermodynamics; Titrimetry; Xenopus laevis; Xenopus Proteins | 1999 |
Pore-forming action of mastoparan peptides on liposomes: a quantitative analysis.
Topics: Amino Acid Sequence; Animals; Dextrans; Fluorescein-5-isothiocyanate; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Kinetics; Liposomes; Peptides; Phosphatidylcholines; Protein Binding; Wasp Venoms | 1999 |
A biomimetic phospholipid/alkanethiolate bilayer immobilizing uricase and an electron mediator on an Au electrode for amperometric determination of uric acid.
Topics: Electrochemistry; Electrodes; Electrons; Enzymes, Immobilized; Gold; Humans; Lipid Bilayers; Methylphenazonium Methosulfate; Phosphatidylcholines; Phospholipids; Reference Values; Sensitivity and Specificity; Sulfhydryl Compounds; Urate Oxidase; Uric Acid | 1999 |
Interaction of pulmonary surfactant protein A with phospholipid liposomes: a kinetic study on head group and fatty acid specificity.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Kinetics; Liposomes; Phosphatidylcholines; Phospholipids; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants | 1999 |
Exchange of C(16)-ceramide between phospholipid vesicles.
Topics: Cell Membrane; Ceramides; In Vitro Techniques; Liposomes; Membrane Lipids; Particle Size; Phosphatidylcholines; Phospholipids; Second Messenger Systems | 1999 |
Molecular dynamics of synthetic leucine-serine ion channels in a phospholipid membrane.
Topics: Amino Acid Sequence; Cell Membrane; Ion Channels; Leucine; Molecular Dynamics Simulation; Molecular Sequence Data; Phosphatidylcholines; Porosity; Protein Structure, Secondary; Serine; Substrate Specificity; Water | 1999 |
Combined Monte Carlo and molecular dynamics simulation of fully hydrated dioleyl and palmitoyl-oleyl phosphatidylcholine lipid bilayers.
Topics: Lipid Bilayers; Molecular Conformation; Molecular Dynamics Simulation; Monte Carlo Method; Phosphatidylcholines; Thermodynamics; Time Factors; Water | 1999 |
The mechanism of membrane insertion for a cholesterol-dependent cytolysin: a novel paradigm for pore-forming toxins.
Topics: Amino Acid Sequence; Amino Acid Substitution; Bacterial Toxins; Clostridium perfringens; Cysteine; Fluorescent Dyes; Hemolysin Proteins; Liposomes; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphatidylcholines; Protein Structure, Secondary; Recombinant Proteins; Spin Labels | 1999 |
Effect of lipid unsaturation on the binding of native and a mutant form of cytochrome b5 to membranes.
Topics: Bromine; Chromatography, Gel; Cytochromes b5; Escherichia coli; Fluorescent Dyes; Lipid Bilayers; Membrane Proteins; Mutagenesis, Site-Directed; Osmolar Concentration; Phosphatidylcholines; Protein Binding; Spectrometry, Fluorescence; Tryptophan | 1999 |
Interaction of the N-terminus of sterol carrier protein 2 with membranes: role of membrane curvature.
Topics: Binding Sites; Carrier Proteins; Cholesterol; Circular Dichroism; Liposomes; Molecular Conformation; Particle Size; Peptide Fragments; Phosphatidylcholines; Phosphatidylserines; Plant Proteins; Protein Binding; Protein Structure, Secondary | 1999 |
CTP:phosphocholine cytidylyltransferase activation by oxidized phosphatidylcholines correlates with a decrease in lipid order: a 2H NMR analysis.
Topics: Catalysis; Choline-Phosphate Cytidylyltransferase; Deuterium; Enzyme Activation; Glycine max; Lipid Bilayers; Lipoproteins, LDL; Lipoxygenase; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Phosphatidylcholines; Phospholipid Ethers; Sphingomyelins | 1999 |
The role of interfacial binding in the activation of Streptomyces chromofuscus phospholipase D by phosphatidic acid.
Topics: Barium; Enzyme Activation; Isoenzymes; Kinetics; Lipid Bilayers; Models, Molecular; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Polystyrenes; Protein Binding; Protein Conformation; Resins, Synthetic; Streptomyces; Structure-Activity Relationship | 1999 |
Evaluation of lipid exposure of tryptophan residues in membrane peptides and proteins.
Topics: Bacterial Outer Membrane Proteins; Cytochromes b5; Fluorescent Dyes; In Vitro Techniques; Kinetics; Membrane Lipids; Membrane Proteins; Models, Chemical; Peptides; Phosphatidylcholines; Protein Folding; Spectrometry, Fluorescence; Tryptophan | 1999 |
Reconstitutive refolding of diacylglycerol kinase, an integral membrane protein.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cross-Linking Reagents; Detergents; Diacylglycerol Kinase; Escherichia coli; Lipid Bilayers; Macromolecular Substances; Membrane Proteins; Micelles; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphatidylcholines; Phosphorylcholine; Protein Folding; Urea | 1999 |
Induction of inflammatory mediators in human airway epithelial cells by lipid ozonation products.
Topics: Alkanes; Bronchi; Cells, Cultured; Dinoprostone; Enzyme Activation; Epithelial Cells; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Membrane Lipids; Oxidants, Photochemical; Ozone; Peroxides; Phosphatidylcholines; Phospholipases A; Platelet Activating Factor; Type C Phospholipases | 1999 |
Lipid-free apolipoproteins A-I and A-II promote remodeling of reconstituted high density lipoproteins and alter their reactivity with lecithin:cholesterol acyltransferase.
Topics: Apolipoprotein A-I; Apolipoprotein A-II; Dansyl Compounds; Fluorescence Polarization; Humans; Kinetics; Lipoproteins, HDL; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines; Protein Binding; Recombinant Proteins | 1999 |
Structure and dynamics of K channel pore-lining helices: a comparative simulation study.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Computer Simulation; Drosophila melanogaster; Drosophila Proteins; Humans; Hydrogen Bonding; Kinetics; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Structure, Secondary; Shaker Superfamily of Potassium Channels; Streptomyces | 2000 |
Nucleotide chain length and the morphology of complexes with cationic amphiphiles: (31)P-NMR observations.
Topics: Base Sequence; Cetrimonium; Cetrimonium Compounds; Fatty Acids, Monounsaturated; Lipid Bilayers; Nuclear Magnetic Resonance, Biomolecular; Oligodeoxyribonucleotides; Phosphatidylcholines; Phosphatidylethanolamines; Phosphorus; Poly A; Quaternary Ammonium Compounds; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thionucleotides | 2000 |
Binding of equine infectious anemia virus matrix protein to membrane bilayers involves multiple interactions.
Topics: Amino Acid Sequence; Cell Membrane; Fluorescence; Fluorescence Polarization; Infectious Anemia Virus, Equine; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Recombinant Fusion Proteins; Sequence Alignment; Solutions; Static Electricity; Thermodynamics; Trypsin; Viral Matrix Proteins; Virus Assembly | 2000 |
Interaction of phosphatidylserine synthase from E. coli with lipid bilayers: coupled plasmon-waveguide resonance spectroscopy studies.
Topics: Anisotropy; CDPdiacylglycerol-Serine O-Phosphatidyltransferase; Escherichia coli; Kinetics; Lipid Bilayers; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylglycerols; Substrate Specificity; Surface Plasmon Resonance | 2000 |
Equations of state for POPX lipids at the air/water interface. A comprehensive study.
Topics: Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Phospholipids; Pressure; Surface Properties; Thermodynamics | 2000 |
Liver and intestinal fatty acid-binding proteins obtain fatty acids from phospholipid membranes by different mechanisms.
Topics: 4-Chloro-7-nitrobenzofurazan; Biological Transport; Carrier Proteins; Enterocytes; Fatty Acid-Binding Proteins; Fatty Acids; Fluorescent Dyes; Intestines; Ions; Liposomes; Liver; Myelin P2 Protein; Neoplasm Proteins; Osmolar Concentration; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Sodium Chloride; Thermodynamics | 2000 |
The orientation of helix 4 in apolipoprotein A-I-containing reconstituted high density lipoproteins.
Topics: Amino Acid Sequence; Amino Acid Substitution; Apolipoprotein A-I; Apolipoproteins A; Humans; Lipid Bilayers; Lipoproteins, HDL; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylcholines; Protein Precursors; Protein Structure, Secondary; Sphingomyelins; Tryptophan | 2000 |
Apolipoprotein AII enrichment of HDL enhances their affinity for class B type I scavenger receptor but inhibits specific cholesteryl ester uptake.
Topics: Adrenal Cortex Neoplasms; Animals; Apolipoprotein A-I; Apolipoprotein A-II; Binding, Competitive; CD36 Antigens; Cholesterol Esters; Humans; Lipoproteins; Lipoproteins, HDL; Membrane Proteins; Mice; Phosphatidylcholines; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class B; Tritium; Tumor Cells, Cultured | 2000 |
Correlation of membrane/water partition coefficients of detergents with the critical micelle concentration.
Topics: Biophysical Phenomena; Biophysics; Calorimetry; Detergents; Membrane Lipids; Micelles; Phosphatidylcholines; Surface-Active Agents; Thermodynamics; Water | 2000 |
A (2)H NMR study of macroscopically aligned bilayer membranes containing interfacial hydroxyl residues.
Topics: Biophysical Phenomena; Biophysics; Cholesterol; Deuterium; Deuterium Oxide; Hydroxylation; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylglycerols | 2000 |
2H NMR and polyelectrolyte-induced domains in lipid bilayers.
Topics: Antigens, Polyomavirus Transforming; Cation Exchange Resins; Cetrimonium; Cetrimonium Compounds; Detergents; Deuterium; Electrolytes; Fatty Acids, Monounsaturated; Fluorescent Dyes; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Weight; Phosphatidylcholines; Phosphatidylglycerols; Polystyrenes; Quaternary Ammonium Compounds | 2000 |
Giant phospholipid vesicles: comparison among the whole lipid sample characteristics using different preparation methods: a two photon fluorescence microscopy study.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Microscopy, Electron; Microscopy, Fluorescence; Phosphatidylcholines; Phospholipids; Photons; Solvents; Suspensions; Temperature; Water | 2000 |
Cyclodextrin-catalyzed extraction of fluorescent sterols from monolayer membranes and small unilamellar vesicles.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrins; Cholestenes; Cholesterol; Cyclodextrins; Dose-Response Relationship, Drug; Ergosterol; Ethanol; Kinetics; Membranes, Artificial; Phosphatidylcholines; Spectrometry, Fluorescence; Sterols; Time Factors; Water | 2000 |
Val(659)-->Glu mutation within the transmembrane domain of ErbB-2: effects measured by (2)H NMR in fluid phospholipid bilayers.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Deuterium; Dimerization; Genes, erbB-2; Glycine; Humans; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Point Mutation; Protein Structure, Secondary; Rats; Receptor, ErbB-2; Recombinant Fusion Proteins; Valine | 2000 |
Reduction of membrane fluidity by antibacterial sophoraflavanone G isolated from Sophora exigua.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Fabaceae; Flavanones; Flavonoids; Liposomes; Membrane Fluidity; Phosphatidylcholines; Plants, Medicinal; Thailand | 2000 |
Cholesterol flux between lipid vesicles and apolipoprotein AI discs of variable size and composition.
Topics: Apolipoprotein A-I; Cell Membrane; Cholesterol; Diffusion; Humans; Kinetics; Lipid Metabolism; Lipoproteins, HDL; Phosphatidylcholines; Protein Binding; Time Factors | 2000 |
Giant vesicles as models to study the interactions between membranes and proteins.
Topics: Cell Membrane; Deoxyribonucleases; Fluorescent Dyes; Formycins; Liposomes; Molecular Structure; Organic Chemicals; Particle Size; Permeability; Phosphatidylcholines; Proteins; Ribonucleases; Ribonucleotides | 2000 |
Flow cytometry-based biosensor for detection of multivalent proteins.
Topics: Biosensing Techniques; Boron Compounds; Cholera Toxin; Flow Cytometry; Fluorescent Dyes; G(M1) Ganglioside; Humans; Kinetics; Lipid Bilayers; Phosphatidylcholines; Proteins; Sensitivity and Specificity; Serum Albumin; Time Factors | 2000 |
Phospholipid composition of reconstituted high density lipoproteins influences their ability to inhibit endothelial cell adhesion molecule expression.
Topics: Cells, Cultured; Endothelium, Vascular; Humans; Interleukin-1; Lipoproteins, HDL; Liposomes; Phosphatidylcholines; Phospholipids; Structure-Activity Relationship; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 2000 |
Association entropy in adsorption processes.
Topics: Adsorption; Entropy; Ligands; Lipid Bilayers; Oligopeptides; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Proteins | 2000 |
Tethered polymer-supported planar lipid bilayers for reconstitution of integral membrane proteins: silane-polyethyleneglycol-lipid as a cushion and covalent linker.
Topics: Annexin A5; Cytochromes b5; Diffusion; Kinetics; Lipid Bilayers; Liposomes; Membrane Proteins; Microscopy, Fluorescence; Models, Molecular; Phosphatidylcholines; Phosphatidylglycerols; Polyethylene Glycols; Silanes; Structure-Activity Relationship | 2000 |
Modulation of glycophorin A transmembrane helix interactions by lipid bilayers: molecular dynamics calculations.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Algorithms; Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Computer Simulation; Dimerization; Dimyristoylphosphatidylcholine; Glycophorins; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphatidylcholines; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Thermodynamics | 2000 |
Potent inhibition of the aortic smooth muscle maxi-K channel by clinical doses of ethanol.
Topics: Animals; Calcium; Cattle; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; In Vitro Techniques; Ion Channel Gating; Ion Transport; Large-Conductance Calcium-Activated Potassium Channels; Lipid Bilayers; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Permeability; Phosphatidylcholines; Phosphatidylethanolamines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated | 2000 |
Thermal unbinding of highly oriented phospholipid membranes.
Topics: Dimyristoylphosphatidylcholine; Lipid Bilayers; Phosphatidylcholines; Phospholipids; Scattering, Radiation; Silicon; Temperature; Thermodynamics; Water; X-Rays | 2000 |
Partly folded states of bovine carbonic anhydrase interact with zwitterionic and anionic lipid membranes.
Topics: Acrylamide; Animals; Anions; Carbonic Anhydrases; Cattle; Chromatography, Gel; Hydrogen-Ion Concentration; Lipid Bilayers; Osmolar Concentration; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Protein Folding; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared | 2000 |
A transmembrane peptide from the human EGF receptor: behaviour of the cytoplasmic juxtamembrane domain in lipid bilayers.
Topics: Amino Acid Sequence; Cytoplasm; ErbB Receptors; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Phosphatidylserines; Protein Transport; Temperature | 2000 |
Effect of fenitrothion on dipalmitoyl and 1-palmitoyl-2-oleoylphosphatidylcholine bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Anisotropy; Crystallization; Fenitrothion; Gels; Insecticides; Lipid Bilayers; Phosphatidylcholines; Spectrometry, Fluorescence | 2000 |
The effect of Zn(2+) on the secondary structure of a histidine-rich fusogenic peptide and its interaction with lipid membranes.
Topics: Amino Acid Sequence; Animals; Cations, Divalent; Histidine; Membrane Fusion; Membrane Lipids; Membranes, Artificial; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Sea Urchins; Spectrophotometry, Infrared; Thermodynamics; Zinc | 2000 |
PMP1 18-38, a yeast plasma membrane protein fragment, binds phosphatidylserine from bilayer mixtures with phosphatidylcholine: a (2)H-NMR study.
Topics: Amino Acid Sequence; Biophysical Phenomena; Biophysics; Deuterium; Fungal Proteins; Lipid Bilayers; Macromolecular Substances; Magnetic Resonance Spectroscopy; Membrane Proteins; Models, Chemical; Molecular Sequence Data; Nerve Tissue Proteins; Peptide Fragments; Phosphatidylcholines; Phosphatidylethanolamines; Protein Binding; Proteolipids; Proton-Translocating ATPases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Static Electricity | 2000 |
Mechanism of annexin I-mediated membrane aggregation.
Topics: Annexin A1; Cross-Linking Reagents; Formaldehyde; Humans; Membrane Lipids; Models, Biological; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Protein Binding; Spectrum Analysis; Surface Plasmon Resonance; X-Rays | 2000 |
Structural information from multilamellar liposomes at full hydration: full q-range fitting with high quality x-ray data.
Topics: Liposomes; Models, Molecular; Phosphatidylcholines; Phosphatidylethanolamines; Scattering, Radiation; Water; X-Ray Diffraction | 2000 |
Rhodopsin activation affects the environment of specific neighboring phospholipids: an FTIR spectroscopic study.
Topics: Amino Acid Substitution; Animals; Cattle; Lipid Bilayers; Phosphatidylcholines; Phospholipids; Protein Conformation; Recombinant Proteins; Rhodopsin; Rod Cell Outer Segment; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship | 2000 |
The role of surfactant proteins in DPPC enrichment of surface films.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Glycoproteins; Liposomes; Phosphatidylcholines; Phosphatidylglycerols; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Surface Properties; Swine | 2000 |
Spread monomolecular films of monohydroxy bile acids and their salts: influence of hydroxyl position, bulk pH, and association with phosphatidylcholine.
Topics: Hydrogen-Ion Concentration; Isomerism; Lithocholic Acid; Micelles; Models, Molecular; Phosphatidylcholines; Phospholipids; Potentiometry; Pressure; Solutions; Surface Properties | 2000 |
Voltage-dependent insertion of alamethicin at phospholipid/water and octane/water interfaces.
Topics: Alamethicin; Amino Acid Sequence; Biophysical Phenomena; Biophysics; Computer Simulation; Drug Stability; Electrochemistry; Lipid Bilayers; Membrane Potentials; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Octanes; Peptides; Phosphatidylcholines; Phospholipids; Protein Structure, Secondary; Static Electricity; Water | 2001 |
Molecular dynamics study of peptide-bilayer adsorption.
Topics: Adsorption; Biophysical Phenomena; Biophysics; Computer Simulation; In Vitro Techniques; Lipid Bilayers; Macromolecular Substances; Models, Molecular; Octreotide; Peptides; Phosphatidylcholines; Protein Binding; Protein Conformation; Surface Properties; Thermodynamics; Water | 2001 |
Biphasic effects of acetaldehyde-biogenic amine condensation products on membrane fluidity.
Topics: Acetaldehyde; Biogenic Amines; Cholesterol; Liposomes; Membrane Fluidity; Phosphatidylcholines | 2001 |
Combined Monte Carlo and molecular dynamics simulation of hydrated lipid-cholesterol lipid bilayers at low cholesterol concentration.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Kinetics; Lipid Bilayers; Models, Biological; Models, Molecular; Models, Statistical; Molecular Conformation; Monte Carlo Method; Phosphatidylcholines | 2001 |
Lipid rafts reconstituted in model membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; 2-Naphthylamine; Animals; Cholesterol; Fluorescent Dyes; G(M1) Ganglioside; Kidney Cortex; Laurates; Lipid Bilayers; Membrane Lipids; Microscopy, Fluorescence; Microvilli; Models, Biological; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Sprague-Dawley; Sphingomyelins | 2001 |
Optical anisotropy in lipid bilayer membranes: coupled plasmon-waveguide resonance measurements of molecular orientation, polarizability, and shape.
Topics: Anisotropy; Birefringence; Boron Compounds; Equipment Design; Fluorescent Dyes; Lipid Bilayers; Orientation; Phosphatidylcholines; Proteolipids; Surface Plasmon Resonance | 2001 |
Stereospecificity in membrane effects of catechins.
Topics: 1-Naphthylamine; 1,2-Dipalmitoylphosphatidylcholine; Anilino Naphthalenesulfonates; Catechin; Chromatography, High Pressure Liquid; Diphenylhexatriene; Flavonoids; Fluorescence Polarization; Fluorescent Dyes; Liposomes; Membrane Fluidity; Membranes, Artificial; Phosphatidylcholines; Stereoisomerism; Structure-Activity Relationship | 2001 |
Role of individual amino acids of apolipoprotein A-I in the activation of lecithin:cholesterol acyltransferase and in HDL rearrangements.
Topics: Amino Acids; Apolipoprotein A-I; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Circular Dichroism; Dimyristoylphosphatidylcholine; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Lipoproteins, HDL; Liposomes; Mutagenesis, Site-Directed; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence; Structure-Activity Relationship | 2001 |
Apolipoprotein A-II modulates the binding and selective lipid uptake of reconstituted high density lipoprotein by scavenger receptor BI.
Topics: Animals; Apolipoprotein A-I; Apolipoprotein A-II; Binding, Competitive; CD36 Antigens; Cell Line; CHO Cells; Cholesterol; Cholesterol Esters; Cricetinae; Humans; Kinetics; Lipoproteins, HDL; Membrane Proteins; Phosphatidylcholines; Phospholipids; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Recombinant Proteins; Scavenger Receptors, Class B | 2001 |
Stimulation of cardiac L-type calcium channels by extracellular ATP.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium Channels, L-Type; Extracellular Space; Heart; Heart Ventricles; Ion Channel Gating; Lipid Bilayers; Patch-Clamp Techniques; Phosphatidylcholines; Phosphatidylethanolamines; Sarcolemma; Swine; Uridine; Uridine Triphosphate | 2001 |
Structural determinants of MscL gating studied by molecular dynamics simulations.
Topics: Computer Simulation; Crystallography, X-Ray; Escherichia coli Proteins; Hydrogen Bonding; Ion Channels; Lipid Bilayers; Models, Molecular; Mycobacterium tuberculosis; Osmosis; Patch-Clamp Techniques; Phosphatidylcholines; Pressure; Protein Conformation; Protein Structure, Secondary; Temperature; Time Factors | 2001 |
Evidence that apolipoprotein A-I facilitates hepatic lipase-mediated phospholipid hydrolysis in reconstituted HDL containing apolipoprotein A-II.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Apolipoprotein A-I; Apolipoprotein A-II; Binding, Competitive; Carbon Radioisotopes; Cholesterol; Drug Synergism; Enzyme Inhibitors; Humans; Hydrolysis; Kinetics; Lipase; Lipoproteins, HDL; Liver; Micelles; Phosphatidylcholines; Phospholipids | 2001 |
Structure of the transmembrane dimer interface of glycophorin A in membrane bilayers.
Topics: Amino Acid Sequence; Dimerization; Dimyristoylphosphatidylcholine; Glycophorins; Humans; Lipid Bilayers; Membrane Glycoproteins; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphatidylcholines; Protein Structure, Secondary; Protein Structure, Tertiary; Surface Properties | 2001 |
Fluorescence quenching of anthracene by indole derivatives in phospholipid bilayers.
Topics: Anthracenes; Fluorescence; Fluorescent Dyes; Indoleacetic Acids; Indoles; Lipid Bilayers; Phosphatidylcholines; Phospholipids | 2001 |
Protein chemistry at membrane interfaces: non-additivity of electrostatic and hydrophobic interactions.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Antimicrobial Cationic Peptides; Bee Venoms; Cell Membrane; Membrane Proteins; Models, Molecular; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Phospholipases A; Protein Binding; Protein Conformation; Solvents; Static Electricity; Thermodynamics; Water | 2001 |
Folding of beta-sheets in membranes: specificity and promiscuity in peptide model systems.
Topics: Amino Acid Sequence; Circular Dichroism; Glycine; Hydrogen Bonding; Hydrogen-Ion Concentration; Liposomes; Membrane Proteins; Membranes, Artificial; Models, Molecular; Peptides; Phosphatidylcholines; Protein Engineering; Protein Folding; Protein Structure, Secondary; Solubility; Spectrometry, Fluorescence | 2001 |
Effects of phospholipid unsaturation on the membrane/water interface: a molecular simulation study.
Topics: Binding Sites; Dimyristoylphosphatidylcholine; Hydrogen Bonding; Lipid Bilayers; Models, Molecular; Oleic Acid; Oleic Acids; Phosphatidylcholines; Phospholipids; Static Electricity; Water | 2001 |
Reconstituted syntaxin1a/SNAP25 interacts with negatively charged lipids as measured by lateral diffusion in planar supported bilayers.
Topics: Anions; Antigens, Surface; Carrier Proteins; Diffusion; Lipid Bilayers; Liposomes; Macromolecular Substances; Membrane Proteins; Microscopy, Fluorescence; Molecular Conformation; Nerve Tissue Proteins; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylserines; Polyethylene Glycols; Polymers; Protein Binding; Quartz; SNARE Proteins; Solubility; Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins; Synaptosomal-Associated Protein 25; Syntaxin 1; Vesicular Transport Proteins | 2001 |
Domain formation in models of the renal brush border membrane outer leaflet.
Topics: Animals; Cattle; Cholesterol; Kidney; Membrane Microdomains; Microscopy, Atomic Force; Microvilli; Phosphatidylcholines; Sphingomyelins | 2001 |
Facilitated phosphatidylcholine flip-flop across erythrocyte membranes using low molecular weight synthetic translocases.
Topics: Biological Transport; Chlorpromazine; Erythrocyte Membrane; Erythrocytes; Fluorescent Dyes; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Phosphatidylcholines; Phospholipids; Transferases | 2001 |
Profile of changes in lipid bilayer structure caused by beta-amyloid peptide.
Topics: 2-Naphthylamine; Amyloid beta-Peptides; Cations; Diphenylhexatriene; Fatty Acids, Monounsaturated; Fluorescence Polarization; Fluorescent Dyes; Humans; Laurates; Lipid Bilayers; Liposomes; Membrane Fluidity; Phosphatidylcholines; Phosphatidylglycerols; Quaternary Ammonium Compounds; Spectrometry, Fluorescence; Surface Properties; Time Factors | 2001 |
Membrane interactions of a new class of anticancer agents derived from arylchloroethylurea: a FTIR spectroscopic study.
Topics: Antineoplastic Agents; Cell Membrane; Chemical Phenomena; Chemistry, Physical; Dimyristoylphosphatidylcholine; In Vitro Techniques; Lipid Bilayers; Membranes, Artificial; Phosphatidylcholines; Phosphatidylglycerols; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Thermodynamics; Urea | 2001 |
Kinetic study of folding and misfolding of diacylglycerol kinase in model membranes.
Topics: Amino Acid Sequence; Detergents; Diacylglycerol Kinase; Escherichia coli; Glucosides; Guanidine; Kinetics; Lipid Bilayers; Micelles; Models, Chemical; Molecular Sequence Data; Phosphatidylcholines; Protein Denaturation; Protein Folding; Reproducibility of Results; Solutions; Ultracentrifugation; Urea | 2001 |
15N and 31P solid-state NMR investigations on the orientation of zervamicin II and alamethicin in phosphatidylcholine membranes.
Topics: Alamethicin; Amino Acid Sequence; Anti-Bacterial Agents; Hypocreales; Lipid Bilayers; Molecular Sequence Data; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Peptaibols; Peptides; Phosphatidylcholines; Phosphorus Isotopes; Protons; Water | 2001 |
Membrane binding and self-association of alpha-synucleins.
Topics: alpha-Synuclein; beta-Synuclein; Blotting, Western; Cell Membrane; Circular Dichroism; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Humans; Hydrogen-Ion Concentration; Lipids; Nerve Tissue Proteins; Neurodegenerative Diseases; Phosphatidylcholines; Phosphatidylethanolamines; Phosphorylation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Silver Staining; Spectrometry, Fluorescence; Synucleins | 2001 |
Detergent-like action of the antibiotic peptide surfactin on lipid membranes.
Topics: Bacterial Proteins; Calorimetry; Detergents; Lipopeptides; Liposomes; Micelles; Peptides, Cyclic; Phosphatidylcholines; Solubility; Temperature; Thermodynamics | 2001 |
The C1 domain of protein kinase C as a lipid bilayer surface sensing module.
Topics: Animals; Brain; Fluorescence Polarization; Isoenzymes; Kinetics; Lipid Bilayers; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Rats; Recombinant Proteins | 2001 |
'Detergent-like' permeabilization of anionic lipid vesicles by melittin.
Topics: Circular Dichroism; Detergents; Melitten; Membranes, Artificial; Particle Size; Permeability; Phosphatidylcholines; Phosphatidylglycerols | 2001 |
Characterization of mixed monolayers of phosphatidylcholine and a dicationic gemini surfactant SS-1 with a langmuir balance: effects of DNA.
Topics: DNA; Membrane Potentials; Membranes, Artificial; Phosphatidylcholines; Quaternary Ammonium Compounds; Surface-Active Agents | 2001 |
A long-lived amphiphilic fluorescent probe studied in POPC air-water monolayer and solution bilayer systems.
Topics: Fluorescent Dyes; Lipid Bilayers; Micelles; Molecular Conformation; Phosphatidylcholines; Spectrometry, Fluorescence; Surface-Active Agents; Thermodynamics | 2001 |
Helical structure of phospholamban in membrane bilayers.
Topics: Amino Acid Sequence; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cell Membrane; Dimyristoylphosphatidylcholine; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Phosphorylation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rotation; Spectroscopy, Fourier Transform Infrared | 2001 |
Binding of proteolytically processed phospholipase D from Streptomyces chromofuscus to phosphatidylcholine membranes facilitates vesicle aggregation and fusion.
Topics: 4-Chloro-7-nitrobenzofurazan; Barium; Calcium; Cryoelectron Microscopy; Endopeptidases; Energy Transfer; Hydrolysis; Ligands; Light; Liposomes; Membrane Fusion; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Protein Binding; Protein Processing, Post-Translational; Scattering, Radiation; Spectrometry, Fluorescence; Streptomyces | 2001 |
Polyelectrolyte molecular weight and electrostatically-induced domains in lipid bilayer membranes.
Topics: Electrochemistry; Electrolytes; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Weight; Oleic Acids; Phosphatidylcholines; Polymers; Polystyrenes; Propylamines | 2000 |
Effects of hemagglutinin fusion peptide on poly(ethylene glycol)-mediated fusion of phosphatidylcholine vesicles.
Topics: Hemagglutinin Glycoproteins, Influenza Virus; Liposomes; Membrane Fusion; Peptide Fragments; Peptides; Phosphatidylcholines; Polyethylene Glycols; Viral Fusion Proteins | 2001 |
Interaction of the alpha-helices of apolipophorin III with the phospholipid acyl chains in discoidal lipoprotein particles: a fluorescence quenching study.
Topics: Amino Acid Sequence; Animals; Apolipoproteins; Bromosuccinimide; Carrier Proteins; Grasshoppers; Lipid Bilayers; Lipoproteins; Molecular Sequence Data; Mutation; Phosphatidylcholines; Phospholipids; Protein Binding; Protein Structure, Secondary; Spectrometry, Fluorescence; Tryptophan | 2001 |
Channel activity of a phytotoxin of Clavibacter michiganense ssp. nebraskense in tethered membranes.
Topics: Actinomycetales; Cell Membrane; Chlorine; Electric Conductivity; Electric Impedance; Electrophysiology; Gold; Inhibitory Concentration 50; Ion Channels; Kinetics; Lipid Bilayers; Lipids; Models, Chemical; Phosphatidylcholines | 2001 |
Membrane topography of the coupling ion binding site in Na+-translocating F1F0 ATP synthase.
Topics: Adenosine Triphosphatases; Binding Sites; Carbodiimides; Cation Transport Proteins; Cell Membrane; Fusobacterium; Ions; Liposomes; Molecular Conformation; Phosphatidylcholines; Protein Subunits; Proton-Translocating ATPases; Sodium; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2002 |
Activation of protein kinase C alpha by lipid mixtures containing different proportions of diacylglycerols.
Topics: Calorimetry, Differential Scanning; Diglycerides; Isoenzymes; Magnetic Resonance Spectroscopy; Membrane Lipids; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Temperature | 2001 |
General aspects of peptide selectivity towards lipid bilayers and cell membranes studied by variation of the structural parameters of amphipathic helical model peptides.
Topics: Anti-Bacterial Agents; Bacillus subtilis; Cell Membrane; Cell Membrane Permeability; Escherichia coli; Fluoresceins; Fluorescent Dyes; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Models, Molecular; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Static Electricity; Structure-Activity Relationship | 2002 |
The presence of PEG-lipids in liposomes does not reduce melittin binding but decreases melittin-induced leakage.
Topics: Adsorption; Ceramides; Lipids; Liposomes; Melitten; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; Spectrophotometry, Infrared | 2002 |
Structure of docosahexaenoic acid-containing phospholipid bilayers as studied by (2)H NMR and molecular dynamics simulations.
Topics: Computer Simulation; Deuterium; Docosahexaenoic Acids; Kinetics; Lipid Bilayers; Models, Molecular; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Scattering, Radiation; Thermodynamics; X-Rays | 2002 |
Role of procoagulant lipids in human prothrombin activation. 1. Prothrombin activation by factor X(a) in the absence of factor V(a) and in the absence and presence of membranes.
Topics: Animals; Binding Sites; Cattle; Enzyme Activation; Factor Va; Factor Xa; Humans; Kinetics; Liposomes; Phosphatidylcholines; Phosphatidylserines; Prothrombin; Thrombin | 2002 |
Behavior of a photoactivatable analog of cholesterol, 6-photocholesterol, in model membranes.
Topics: Cholesterol; Hydrogen-Ion Concentration; Lipid Bilayers; Liposomes; Membrane Fusion; Membranes, Artificial; Models, Biological; Molecular Probes; Phosphatidylcholines; Photochemistry; Semliki forest virus; Sindbis Virus; Sterols | 2002 |
Specific binding of Ro 09-0198 (cinnamycin) to phosphatidylethanolamine: a thermodynamic analysis.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacteriocins; Calorimetry; In Vitro Techniques; Kinetics; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides; Peptides, Cyclic; Phosphatidylcholines; Phosphatidylethanolamines; Protein Binding; Thermodynamics | 2002 |
Evidence of a tendency to self-association of the transmembrane domain of ErbB-2 in fluid phospholipid bilayers.
Topics: Amino Acid Sequence; Cholesterol; Dimerization; Humans; Lipid Bilayers; Membrane Fluidity; Membrane Proteins; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphatidylcholines; Phospholipids; Point Mutation; Protein Structure, Tertiary; Receptor, ErbB-2; Temperature; Thermodynamics | 2002 |
Interaction of apolipoprotein A-I in three different conformations with palmitoyl oleoyl phosphatidylcholine vesicles.
Topics: Apolipoprotein A-I; Binding Sites; Calorimetry; Humans; Lipoproteins, HDL; Membrane Lipids; Membranes, Artificial; Microscopy, Fluorescence; Molecular Conformation; Phosphatidylcholines | 2002 |
Method-dependent changes in "HDL-cholesterol" with recombinant apolipoprotein A-I(Milano) infusion in healthy volunteers.
Topics: Apolipoprotein A-I; Cholesterol, HDL; Humans; Phosphatidylcholines; Recombinant Proteins | 2002 |
Enhancement of steric repulsion with temperature in oriented lipid multilayers.
Topics: Dimyristoylphosphatidylcholine; Lipid Bilayers; Osmotic Pressure; Phosphatidylcholines; Temperature | 2002 |
A two-photon view of an enzyme at work: Crotalus atrox venom PLA2 interaction with single-lipid and mixed-lipid giant unilamellar vesicles.
Topics: 2-Naphthylamine; Animals; Crotalid Venoms; Crotalus; Dimyristoylphosphatidylcholine; Fluorescent Dyes; Hydrolysis; Kinetics; Laurates; Lipid Metabolism; Microscopy, Fluorescence; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Phospholipids; Photons; Protein Binding; Protein Structure, Tertiary; Time Factors | 2002 |
Interactions of cyclosporines with lipid membranes as studied by solid-state nuclear magnetic resonance spectroscopy and high-sensitivity titration calorimetry.
Topics: Algorithms; Amino Acids; Calorimetry; Circular Dichroism; Cyclosporins; Deuterium; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Serum Albumin, Bovine; Solubility; Thermodynamics; Ultraviolet Rays | 2002 |
Differential effects of temperature on E. coli and synthetic polyhydroxybutyrate/polyphosphate channels.
Topics: Calcium Channels; Cell Membrane; Cholesterol; Electric Conductivity; Escherichia coli; Hot Temperature; Hydroxybutyrates; Ion Channel Gating; Lipid Bilayers; Phosphatidylcholines; Polyesters; Polyphosphates; Temperature | 2002 |
An innovative procedure using a sublimable solid to align lipid bilayers for solid-state NMR studies.
Topics: Amino Acid Sequence; Amino Acids; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Structure-Activity Relationship | 2002 |
Facilitated phospholipid flip-flop using synthetic steroid-derived translocases.
Topics: 4-Chloro-7-nitrobenzofurazan; Cell Membrane; Cholates; Dithionite; Fluorescent Dyes; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Transferases | 2002 |
Giant vesicles as microreactors for enzymatic mRNA synthesis.
Topics: Calcium; DNA Primers; DNA-Directed DNA Polymerase; Ethanol; Green Fluorescent Proteins; Humans; Liposomes; Luminescent Proteins; Membranes, Artificial; Microinjections; Phosphatidylcholines; Plasmids; Polymerase Chain Reaction; RNA, Messenger | 2002 |
Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling.
Topics: Calcium-Binding Proteins; Cell Membrane; Cytosol; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Spin Labels; Thermodynamics | 2002 |
Liposomes from novel photolabile phospholipids: light-induced unloading of small molecules as monitored by PFG NMR.
Topics: Cholesterol; Light; Liposomes; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phospholipids; Photochemistry; Pyridines; Quinolizines; Sulfur Compounds | 2002 |
The effect of ceramide on phosphatidylcholine membranes: a deuterium NMR study.
Topics: Biophysical Phenomena; Biophysics; Ceramides; Deuterium; In Vitro Techniques; Magnetic Resonance Spectroscopy; Membrane Lipids; Phosphatidylcholines; Thermodynamics; Water | 2002 |
Organization of model helical peptides in lipid bilayers: insight into the behavior of single-span protein transmembrane domains.
Topics: Alanine; Amino Acid Sequence; Biophysical Phenomena; Biophysics; Dimerization; Electrophoresis, Polyacrylamide Gel; Leucine; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Structure, Tertiary; Temperature | 2002 |
Computational modeling of DNA-cationic lipid complexation.
Topics: Cations; Computer Simulation; DNA; Lipids; Liposomes; Models, Chemical; Phosphatidylcholines | 2002 |
Lateral organization of GM1 in phase-separated monolayers visualized by scanning force microscopy.
Topics: Brain; Cholesterol; G(M1) Ganglioside; Lipid Bilayers; Lipids; Membranes, Artificial; Microscopy, Atomic Force; Phosphatidylcholines; Sphingomyelins | 2002 |
Mechanisms of equinatoxin II-induced transport through the membrane of a giant phospholipid vesicle.
Topics: Animals; Biological Transport; Biophysical Phenomena; Biophysics; Cnidarian Venoms; Phosphatidylcholines; Phospholipids; Sea Anemones; Time Factors | 2002 |
Membrane composition determines pardaxin's mechanism of lipid bilayer disruption.
Topics: Animals; Calorimetry, Differential Scanning; Cell Membrane; Cholesterol; Fish Venoms; Fishes; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membranes; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Temperature | 2002 |
Lipid-free structure and stability of apolipoprotein A-I: probing the central region by mutation.
Topics: Amino Acid Substitution; Apolipoprotein A-I; Cholesterol, HDL; Dimyristoylphosphatidylcholine; Guanidine; Hot Temperature; Humans; Kinetics; Lipids; Liposomes; Mutagenesis, Site-Directed; Particle Size; Peptide Fragments; Phosphatidylcholines; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Sequence Deletion; Spectrometry, Fluorescence | 2002 |
Bridging implicit and explicit solvent approaches for membrane electrostatics.
Topics: Algorithms; Biophysical Phenomena; Biophysics; Cell Membrane; Computer Simulation; Lipid Bilayers; Membranes, Artificial; Models, Theoretical; Phosphatidylcholines; Poisson Distribution; Solvents; Static Electricity | 2002 |
Mechanism and kinetics of delta-lysin interaction with phospholipid vesicles.
Topics: Amino Acid Sequence; Bacterial Proteins; Coumarins; Energy Transfer; Fluoresceins; Hemolysin Proteins; Kinetics; Lipid Bilayers; Models, Chemical; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Phospholipids; Solutions; Spectrometry, Fluorescence; Staphylococcus aureus; Tryptophan; Water | 2002 |
Mast cell chymase degrades apoE and apoA-II in apoA-I-knockout mouse plasma and reduces its ability to promote cellular cholesterol efflux.
Topics: Animals; Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins E; Biological Transport, Active; Cholesterol; Chymases; Female; Foam Cells; Humans; Lipoproteins; Lipoproteins, HDL; Liposomes; Macrophages, Peritoneal; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylcholines; Proteins; Recombinant Fusion Proteins; Secretory Vesicles; Serine Endopeptidases | 2002 |
Increased antioxidant reactivity of vitamin C at low pH in model membranes.
Topics: Antioxidants; Ascorbic Acid; Bridged Bicyclo Compounds, Heterocyclic; Fluorescence; Fluorescent Dyes; Hydrogen-Ion Concentration; Kinetics; Liposomes; Membranes; Micelles; Microscopy, Fluorescence; Octoxynol; Phosphatidylcholines; Sodium Dodecyl Sulfate | 2002 |
Membrane insertion and dissociation processes of a model transmembrane helix.
Topics: Alanine; Entropy; Fluorescence Resonance Energy Transfer; Leucine; Lipid Bilayers; Membrane Potentials; Membranes, Artificial; Models, Chemical; Models, Molecular; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Protein Structure, Secondary; Protein Transport; Temperature | 2002 |
Evidence that phospholipids play a key role in pre-beta apoA-I formation and high-density lipoprotein remodeling.
Topics: Apolipoprotein A-I; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Electrophoresis, Polyacrylamide Gel; Emulsions; Glycoproteins; High-Density Lipoproteins, Pre-beta; Humans; Lipoproteins, HDL; Phosphatidylcholines; Phospholipid Ethers; Phospholipids; Surface Plasmon Resonance | 2002 |
Topology and secondary structure of the N-terminal domain of diacylglycerol kinase.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cross-Linking Reagents; Cysteine; Diacylglycerol Kinase; Escherichia coli Proteins; Fluorine; Gadolinium DTPA; Glucosides; Micelles; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphatidylcholines; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Thermodynamics | 2002 |
Surface plasmon resonance characterization of drug/liposome interactions.
Topics: Biosensing Techniques; Cholesterol; Dimethyl Sulfoxide; Kinetics; Liposomes; Membrane Fluidity; Pharmaceutical Preparations; Phosphatidylcholines; Reproducibility of Results; Surface Plasmon Resonance; Surface Properties; Temperature | 2002 |
Beta-amyloid 25 to 35 is intercalated in anionic and zwitterionic lipid membranes to different extents.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Anions; Biophysical Phenomena; Biophysics; Deuterium Oxide; Humans; Ions; Lipid Bilayers; Models, Statistical; Neutrons; Peptide Fragments; Peptides; Phosphatidylcholines | 2002 |
Shapes of phospholipid [correction of phosholipid] vesicles with beadlike protrusions.
Topics: Computer Simulation; Elasticity; Electrochemistry; Lipid Bilayers; Liposomes; Macromolecular Substances; Membrane Fluidity; Microscopy, Phase-Contrast; Microscopy, Video; Microspheres; Microvilli; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Phospholipids | 2002 |
The role of surface free energy on the formation of hybrid bilayer membranes.
Topics: Adsorption; Alkanes; Electric Capacitance; Hydrocarbons, Fluorinated; Kinetics; Lipid Bilayers; Membranes; Microscopy, Atomic Force; Phosphatidylcholines; Sulfhydryl Compounds; Surface Plasmon Resonance; Surface Properties; Thermodynamics | 2002 |
Effects of cholesterol on surface activity and surface topography of spread surfactant films.
Topics: Adsorption; Animals; Cattle; Cholesterol; Drug Combinations; Lipid Bilayers; Microscopy, Atomic Force; Phosphatidylcholines; Phosphatidylglycerols; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Protein C; Surface Properties; Surface Tension; Swine | 2002 |
The interaction of alpha-tocopherol with bilayers of 1-palmitoyl-2-oleoyl-phosphatidylcholine.
Topics: alpha-Tocopherol; Lipid Bilayers; Microscopy, Electron; Phosphatidylcholines; X-Ray Diffraction | 2002 |
A rapid method for assessing lipid:protein and detergent:protein ratios in membrane-protein crystallization.
Topics: Amides; Crystallization; Filtration; Membrane Proteins; Micelles; Muramidase; Phosphatidylcholines; Protein Structure, Secondary; Solubility; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents | 2003 |
Membrane-bound orientation and position of the synaptotagmin I C2A domain by site-directed spin labeling.
Topics: Binding Sites; Calcium; Calcium-Binding Proteins; Cysteine; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Membrane Glycoproteins; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Spin Labels; Synaptotagmin I; Synaptotagmins; Thermodynamics | 2003 |
Preparation and characterization of reactive and stable glucose oxidase-containing liposomes modulated with detergent.
Topics: Cholates; Coated Materials, Biocompatible; Detergents; Diffusion; Enzyme Activation; Enzyme Stability; Enzymes, Immobilized; Glucose; Glucose Oxidase; Liposomes; Macromolecular Substances; Membrane Fluidity; Octoxynol; Permeability; Phosphatidylcholines; Sensitivity and Specificity; Solutions | 2003 |
Hydration pressure and phase transitions of phospholipids. I. Piezotropic approach.
Topics: Hydrophobic and Hydrophilic Interactions; Hydrostatic Pressure; Mathematics; Phosphatidylcholines; Phospholipids; Spectroscopy, Fourier Transform Infrared; Temperature | 2003 |
Hydration pressure and phase transitions of phospholipids. II. Thermotropic approach.
Topics: Calorimetry, Differential Scanning; Dimyristoylphosphatidylcholine; Hydrostatic Pressure; Osmotic Pressure; Phosphatidylcholines; Phospholipids; Spectroscopy, Fourier Transform Infrared; Temperature; Thermodynamics | 2003 |
Material studies of lipid vesicles in the L(alpha) and L(alpha)-gel coexistence regimes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Elasticity; Gels; Lipid Bilayers; Liposomes; Materials Testing; Micromanipulation; Phosphatidylcholines; Reproducibility of Results; Sensitivity and Specificity; Solutions; Stress, Mechanical; Surface Tension; Temperature; Tensile Strength | 2003 |
Label-free chiral detection of melittin binding to a membrane.
Topics: Amino Acid Sequence; Lipid Bilayers; Melitten; Membranes; Molecular Sequence Data; Phosphatidylcholines; Photons; Protein Binding; Protein Structure, Secondary; Spectrum Analysis; Stereoisomerism | 2003 |
Lipid compositional analysis of pulmonary surfactant monolayers and monolayer-associated reservoirs.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Adsorption; Animals; Cattle; Lipids; Membranes, Artificial; Phosphatidylcholines; Phosphatidylglycerols; Pulmonary Alveoli; Pulmonary Surfactants; Surface Properties | 2003 |
Cholesterol dynamics in membranes of raft composition: a molecular point of view from 2H and 31P solid-state NMR.
Topics: Cholesterol; Deuterium; Dimyristoylphosphatidylcholine; Liposomes; Membrane Microdomains; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phosphatidylethanolamines; Phosphorus Isotopes; Protein Conformation; Sphingomyelins; Thermodynamics | 2003 |
Structural, dynamic and mechanical properties of POPC at low cholesterol concentration studied in pressure/temperature space.
Topics: Cholesterol; Gels; Lipid Bilayers; Materials Testing; Molecular Conformation; Phosphatidylcholines; Pressure; Solutions; Temperature; X-Ray Diffraction | 2003 |
Membrane water-penetration profiles from spin labels.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cell Membrane Permeability; Computer Simulation; Cyclic N-Oxides; Diffusion; Electron Spin Resonance Spectroscopy; Hydrogen Bonding; Lipid Bilayers; Membrane Lipids; Membranes, Artificial; Models, Chemical; Models, Molecular; Phosphatidylcholines; Solutions; Solvents; Spin Labels; Stearic Acids; Water | 2002 |
Size distribution of spontaneously formed liposomes by the alcohol injection method.
Topics: Aging; Alcohols; Chemical Phenomena; Chemistry, Physical; Drug Stability; Hydrogen-Ion Concentration; Liposomes; Particle Size; Phosphatidylcholines; Solutions; Water | 2002 |
Migration of poly-L-lysine through a lipid bilayer.
Topics: Lipid Bilayers; Microscopy, Phase-Contrast; Phosphatidylcholines; Phosphatidylglycerols; Polylysine | 2003 |
Membrane composition affects the reversibility of annexin A2t binding to solid supported membranes: a QCM study.
Topics: Adsorption; Animals; Annexin A2; Brain; Cattle; Cholesterol; Crystallization; Lipid Bilayers; Liposomes; Membrane Lipids; Oscillometry; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Protein Binding; Quartz; Swine | 2003 |
Magainin 2 channel formation in planar lipid membranes: the role of lipid polar groups and ergosterol.
Topics: Antimicrobial Cationic Peptides; Electric Conductivity; Electrochemistry; Ergosterol; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Ion Channels; Lipid Bilayers; Lipids; Magainins; Membrane Potentials; Membranes, Artificial; Permeability; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Porosity; Static Electricity; Xenopus Proteins | 2003 |
Interactions of chicken liver basic fatty acid-binding protein with lipid membranes.
Topics: Animals; Carrier Proteins; Chickens; Fatty Acid-Binding Proteins; Lipid Bilayers; Liver; Neoplasm Proteins; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Spectroscopy, Fourier Transform Infrared; Temperature; X-Ray Diffraction | 2003 |
Molecular dynamics of 1-palmitoyl-2-oleoylphosphatidylcholine membranes containing transmembrane alpha-helical peptides with alternating leucine and alanine residues.
Topics: Alanine; Binding Sites; Biological Transport; Electron Spin Resonance Spectroscopy; Leucine; Lipid Bilayers; Membranes, Artificial; Models, Chemical; Molecular Conformation; Oxygen; Peptide Fragments; Phosphatidylcholines; Protein Structure, Secondary; Temperature | 2003 |
Simulation of MscL gating in a bilayer under stress.
Topics: Biomimetics; Cell Membrane Permeability; Compressive Strength; Computer Simulation; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Lipid Bilayers; Mechanotransduction, Cellular; Membrane Fluidity; Models, Molecular; Motion; Phosphatidylcholines; Porosity; Pressure; Protein Conformation; Protein Structure, Secondary; Protein Subunits; Stress, Mechanical; Tensile Strength; Water | 2003 |
Filter flexibility in a mammalian K channel: models and simulations of Kir6.2 mutants.
Topics: Animals; Cell Membrane Permeability; Computer Simulation; Humans; Ion Channel Gating; Lipid Bilayers; Mammals; Membrane Fluidity; Models, Molecular; Phosphatidylcholines; Porosity; Potassium Channels, Inwardly Rectifying; Protein Conformation; Recombinant Proteins; Reproducibility of Results; Sensitivity and Specificity; Structure-Activity Relationship; Water | 2003 |
Selective transport of ATP across a phospholipid bilayer by a molecular umbrella.
Topics: Adenosine Triphosphate; Arginine; Biological Transport; Cholic Acids; Drug Carriers; Glutathione; Lipid Bilayers; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Spermidine | 2003 |
Application of capillaries with minimized electroosmotic flow to the electrokinetic study of acidic drug-beta-oleoyl-gamma-palmitoyl-L-alpha-phosphatidyl choline liposome interactions.
Topics: Electrophoresis, Capillary; Hydrogen-Ion Concentration; Liposomes; Microscopy, Electron, Scanning; Osmosis; Phosphatidylcholines | 2003 |
MSI-78, an analogue of the magainin antimicrobial peptides, disrupts lipid bilayer structure via positive curvature strain.
Topics: Antimicrobial Cationic Peptides; Lipid Bilayers; Macromolecular Substances; Membrane Fluidity; Molecular Conformation; Motion; Permeability; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Porosity; Protein Precursors; Stress, Mechanical; Xenopus Proteins | 2003 |
Cooperative partition model of nystatin interaction with phospholipid vesicles.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Binding Sites; Computer Simulation; Lipid Bilayers; Liposomes; Macromolecular Substances; Membrane Fluidity; Models, Chemical; Models, Molecular; Nystatin; Phosphatidylcholines; Phospholipids; Polymers; Spectrometry, Fluorescence | 2003 |
The effect of cholesterol on the lateral diffusion of phospholipids in oriented bilayers.
Topics: Cholesterol; Diffusion; Dimyristoylphosphatidylcholine; Lipid Bilayers; Macromolecular Substances; Magnetic Resonance Spectroscopy; Membrane Fluidity; Molecular Conformation; Phase Transition; Phosphatidylcholines; Phospholipids; Solutions; Sphingomyelins; Temperature | 2003 |
Molecular dynamics simulations on the first two helices of Vpu from HIV-1.
Topics: Amino Acid Sequence; Amino Acids; Computer Simulation; HIV-1; Human Immunodeficiency Virus Proteins; Lipid Bilayers; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Motion; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Viral Regulatory and Accessory Proteins | 2003 |
Exclusion of maltodextrins from phosphatidylcholine multilayers during dehydration: effects on membrane phase behaviour.
Topics: Calorimetry, Differential Scanning; Desiccation; Dimyristoylphosphatidylcholine; Lipid Bilayers; Membrane Fluidity; Membranes, Artificial; Osmotic Pressure; Phase Transition; Phosphatidylcholines; Polysaccharides; Temperature; Water | 2003 |
Effect of peptide conformation on membrane permeability.
Topics: Calorimetry, Differential Scanning; Cell Membrane Permeability; Cholesterol; Dialysis; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Kinetics; Lipid Bilayers; Liposomes; Molecular Conformation; Peptides; Phosphatidylcholines; Thermodynamics; Titrimetry | 2003 |
The effect of fructan on membrane lipid organization and dynamics in the dry state.
Topics: Dextrans; Dimyristoylphosphatidylcholine; Fructans; Inulin; Macromolecular Substances; Magnetic Resonance Imaging; Membrane Fluidity; Membrane Lipids; Molecular Conformation; Phosphatidylcholines; Spectroscopy, Fourier Transform Infrared; Temperature; Transition Temperature; Water; Wettability | 2003 |
Time-resolved fluorescence and fourier transform infrared spectroscopic investigations of lateral packing defects and superlattice domains in compositionally uniform cholesterol/phosphatidylcholine bilayers.
Topics: Algorithms; Anisotropy; Cholesterol; Computer Simulation; Lipid Bilayers; Liposomes; Macromolecular Substances; Membrane Fluidity; Models, Molecular; Phosphatidylcholines; Signal Processing, Computer-Assisted; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared | 2003 |
The sensitivity of lipid domains to small perturbations demonstrated by the effect of Triton.
Topics: Animals; Calorimetry, Differential Scanning; Cholesterol; Detergents; Humans; Lipid Bilayers; Membrane Microdomains; Octoxynol; Phosphatidylcholines; Sensitivity and Specificity; Sphingomyelins | 2003 |
Oxidized phospholipids in minimally modified low density lipoprotein induce apoptotic signaling via activation of acid sphingomyelinase in arterial smooth muscle cells.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Death; Cell Division; Cell Survival; Cells, Cultured; Endothelium, Vascular; Genes, Reporter; Humans; Lipoproteins, LDL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth; NF-kappa B; Oxygen; Phosphatidylcholines; Phospholipid Ethers; Phospholipids; Phosphorylation; Plasmids; Protein Isoforms; Rats; Signal Transduction; Sphingomyelin Phosphodiesterase; Time Factors | 2003 |
The implementation of slab geometry for membrane-channel molecular dynamics simulations.
Topics: Alamethicin; Cell Membrane; Computer Simulation; Diffusion; Ion Channels; Lipid Bilayers; Membrane Fluidity; Models, Biological; Models, Chemical; Models, Molecular; Motion; Phosphatidylcholines; Protein Conformation; Static Electricity; Water | 2003 |
Understanding the Hofmeister effect in interactions between chaotropic anions and lipid bilayers: molecular dynamics simulations.
Topics: Anions; Computer Simulation; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Models, Chemical; Models, Molecular; Molecular Conformation; Phosphatidylcholines | 2003 |
A molecular dynamics investigation of mono and dimeric states of the outer membrane enzyme OMPLA.
Topics: Bacterial Outer Membrane Proteins; Binding Sites; Calcium; Computer Simulation; Dimerization; Enzyme Activation; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Models, Molecular; Phosphatidylcholines; Phospholipases A; Phospholipases A1; Protein Conformation | 2003 |
Protein transduction domains of HIV-1 and SIV TAT interact with charged lipid vesicles. Binding mechanism and thermodynamic analysis.
Topics: Animals; Binding Sites; Calorimetry; Deuterium; Gene Products, tat; HIV-1; Humans; Lipid Bilayers; Models, Chemical; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phosphatidylglycerols; Phosphorus Isotopes; Pressure; Protein Binding; Protein Structure, Tertiary; Protein Transport; Scattering, Radiation; Simian Immunodeficiency Virus; Static Electricity; Surface Properties; tat Gene Products, Human Immunodeficiency Virus; Thermodynamics | 2003 |
Regulation of calcium channel activity by lipid domain formation in planar lipid bilayers.
Topics: Calcium Channels; Electric Capacitance; Ion Channel Gating; Lipid Bilayers; Membrane Fluidity; Membrane Microdomains; Membrane Potentials; Membranes, Artificial; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; Protein Conformation; Ryanodine Receptor Calcium Release Channel; Structure-Activity Relationship | 2003 |
The pressure-dependence of the size of extruded vesicles.
Topics: Ceramides; Cholesterol; Lipid Bilayers; Liposomes; Membrane Fluidity; Microfluidics; Models, Chemical; Nanotechnology; Particle Size; Phosphatidylcholines; Surface Tension | 2003 |
Effects of a carane derivative local anesthetic on a phospholipid bilayer studied by molecular dynamics simulation.
Topics: Anesthetics, Local; Bicyclic Monoterpenes; Computer Simulation; Cyclohexylamines; Lipid Bilayers; Macromolecular Substances; Membrane Fluidity; Membranes, Artificial; Models, Molecular; Molecular Conformation; Monoterpenes; Motion; Phosphatidylcholines; Phospholipids | 2003 |
A synthetic surfactant based on a poly-Leu SP-C analog and phospholipids: effects on tidal volumes and lung gas volumes in ventilated immature newborn rabbits.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Humans; Infant, Newborn; Lung; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Tertiary; Pulmonary Surfactant-Associated Protein C; Rabbits; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Tidal Volume | 2003 |
Ordering of water molecules between phospholipid bilayers visualized by coherent anti-Stokes Raman scattering microscopy.
Topics: In Vitro Techniques; Lipid Bilayers; Microscopy; Models, Molecular; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Spectrum Analysis, Raman; Water | 2003 |
Molecular mechanisms of type III hyperlipoproteinemia: The contribution of the carboxy-terminal domain of ApoE can account for the dyslipidemia that is associated with the E2/E2 phenotype.
Topics: Adenoviridae; Animals; Apolipoprotein E2; Apolipoproteins E; Biological Transport, Active; CHO Cells; Cholesterol; Cricetinae; Female; Genes, Dominant; Humans; Hyperlipidemias; Hyperlipoproteinemia Type III; Lipolysis; Lipoprotein Lipase; Lipoproteins, VLDL; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Phosphatidylcholines; Receptors, LDL; Transfection; Triglycerides | 2003 |
Facilitated transport of sodium or potassium chloride across vesicle membranes using a ditopic salt-binding macrobicycle.
Topics: Biological Transport; Chlorides; Electrophysiology; Ions; Magnetic Resonance Spectroscopy; Membranes, Artificial; Models, Chemical; Phosphatidylcholines; Potassium Chloride; Salts; Sodium; Sodium Chloride; Time Factors | 2003 |
Investigating lipid composition effects on the mechanosensitive channel of large conductance (MscL) using molecular dynamics simulations.
Topics: Biophysical Phenomena; Biophysics; Computer Simulation; Crystallography, X-Ray; Escherichia coli; Escherichia coli Proteins; Ion Channels; Lipid Bilayers; Lipids; Models, Biological; Models, Molecular; Molecular Conformation; Mutagenesis; Mycobacterium tuberculosis; Phosphatidylcholines; Phosphatidylethanolamines; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Time Factors | 2003 |
Effect of sodium chloride on a lipid bilayer.
Topics: Biophysical Phenomena; Biophysics; Calorimetry; Carbon; Chlorine; Computer Simulation; Diffusion; Dose-Response Relationship, Drug; Fatty Acids; Lipid Bilayers; Lipids; Models, Chemical; Models, Statistical; Phosphatidylcholines; Sodium Chloride; Spectrometry, Fluorescence; Static Electricity; Time Factors | 2003 |
Lateral diffusion rates of lipid, water, and a hydrophobic drug in a multilamellar liposome.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biophysical Phenomena; Biophysics; Calibration; Diffusion; Ibuprofen; Lipid Bilayers; Lipids; Liposomes; Magnetic Resonance Spectroscopy; Models, Chemical; Phosphatidylcholines; Temperature; Time Factors; Water | 2003 |
The potential of fluorescent and spin-labeled steroid analogs to mimic natural cholesterol.
Topics: Cholesterol; Electron Spin Resonance Spectroscopy; Fluorescent Dyes; Lipid Bilayers; Lipid Metabolism; Lipids; Magnetic Resonance Spectroscopy; Models, Chemical; Phosphatidylcholines; Spectrometry, Fluorescence; Steroids; Time Factors | 2003 |
Domains of apoE required for binding to apoE receptor 2 and to phospholipids: implications for the functions of apoE in the brain.
Topics: Animals; Apolipoproteins E; Binding Sites; Brain; Cell Line; Homeostasis; Humans; LDL-Receptor Related Proteins; Nerve Tissue Proteins; Phosphatidylcholines; Phospholipids; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Receptors, Lipoprotein | 2003 |
Shape transformation and burst of giant POPC unilamellar liposomes modulated by non-ionic detergent C12E8.
Topics: Algorithms; Detergents; Elasticity; Lipid Bilayers; Liposomes; Macromolecular Substances; Membrane Fluidity; Microscopy, Phase-Contrast; Models, Chemical; Molecular Conformation; Particle Size; Permeability; Phosphatidylcholines; Polyethylene Glycols; Surface Properties; Thermodynamics | 2003 |
Internally catalyzed separation of adhered lipid membranes.
Topics: Anions; Catalysis; Liposomes; Membrane Lipids; Phosphatidylcholines; Phosphatidylglycerols; Quaternary Ammonium Compounds | 2003 |
Simultaneous in situ total internal reflectance fluorescence/atomic force microscopy studies of DPPC/dPOPC microdomains in supported planar lipid bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Lipid Bilayers; Liposomes; Microscopy, Atomic Force; Microscopy, Fluorescence; Phosphatidylcholines | 2003 |
Comparison of the effects of surface tension and osmotic pressure on the interfacial hydration of a fluid phospholipid bilayer.
Topics: Betaine; Choline; Computer Simulation; Lipid Bilayers; Liposomes; Membrane Fluidity; Models, Molecular; Osmotic Pressure; Phosphatidylcholines; Solutions; Solvents; Sucrose; Surface Properties; Surface Tension; Water; Water-Electrolyte Balance | 2003 |
Sphingomyelin/phosphatidylcholine/cholesterol phase diagram: boundaries and composition of lipid rafts.
Topics: Cholesterol; Complex Mixtures; Lipid Bilayers; Liposomes; Macromolecular Substances; Membrane Fluidity; Membrane Microdomains; Membranes, Artificial; Molecular Conformation; Phase Transition; Phosphatidylcholines; Sphingomyelins; Surface Properties; Temperature | 2003 |
Temperature-dependence of the solubilization of dipalmitoylphosphatidylcholine (DPPC) by the non-ionic surfactant Triton X-100, kinetic and structural aspects.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Kinetics; Membrane Microdomains; Membranes, Artificial; Octoxynol; Particle Size; Phase Transition; Phosphatidylcholines; Solubility; Temperature | 2003 |
How thin can glass be? New ideas, new approaches.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Glass; Membrane Fluidity; Membrane Lipids; Membranes, Artificial; Molecular Conformation; Motion; Phase Transition; Phosphatidylcholines; Pressure; Pulmonary Surfactants; Surface Properties; Surface Tension; Temperature | 2003 |
Metastability of a supercompressed fluid monolayer.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Membrane Fluidity; Membrane Lipids; Membranes, Artificial; Molecular Conformation; Motion; Phase Transition; Phosphatidylcholines; Pressure; Pulmonary Surfactants; Surface Properties; Surface Tension; Temperature | 2003 |
The effect of fructan on the phospholipid organization in the dry state.
Topics: Desiccation; Fructans; Inulin; Lipid Bilayers; Liposomes; Macromolecular Substances; Membrane Fluidity; Membrane Fusion; Membrane Lipids; Membranes, Artificial; Molecular Conformation; Permeability; Phase Transition; Phosphatidylcholines; Phospholipids; Powders | 2003 |
Adhesion and clustering of charge isomers of myelin basic protein at model myelin membranes.
Topics: Adsorption; Animals; Cattle; Computer Simulation; Isomerism; Lipid Bilayers; Macromolecular Substances; Membrane Fluidity; Membrane Fusion; Membrane Proteins; Membranes, Artificial; Models, Molecular; Myelin Basic Protein; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Spectrum Analysis; Static Electricity; Surface Properties | 2003 |
Membrane mimetic environments alter the conformation of the outer membrane protein BtuB.
Topics: Bacterial Outer Membrane Proteins; Detergents; Electron Spin Resonance Spectroscopy; Escherichia coli Proteins; Lipid Bilayers; Membrane Transport Proteins; Models, Molecular; Phosphatidylcholines; Protein Conformation; Receptors, Peptide | 2003 |
Kinetic evidence for the existence and mechanism of formation of a barrel stave structure from pore-forming dendrimers.
Topics: Cholic Acid; Glutathione; Kinetics; Lipid Bilayers; Liposomes; Lysine; Phosphatidylcholines; Polyamines; Sodium; Spermidine; Spermine; Structure-Activity Relationship | 2003 |
Structure and dynamics of annexin 12 bound to a planar lipid bilayer.
Topics: Annexins; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Models, Molecular; Phosphatidylcholines; Phosphatidylserines; Spin Labels | 2003 |
Insertion of externally administered amyloid beta peptide 25-35 and perturbation of lipid bilayers.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Deuterium; Fourier Analysis; Leucine; Lipid Bilayers; Models, Molecular; Neutron Diffraction; Peptide Fragments; Phosphatidylcholines; Phosphatidylethanolamines; Scattering, Radiation | 2003 |
Orientation and conformation of cell-penetrating peptide penetratin in phospholipid vesicle membranes determined by polarized-light spectroscopy.
Topics: Carrier Proteins; Cell Membrane Permeability; Cell-Penetrating Peptides; Light; Liposomes; Models, Molecular; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Protein Conformation; Spectrum Analysis; Tryptophan | 2003 |
Penetratin and related cell-penetrating cationic peptides can translocate across lipid bilayers in the presence of a transbilayer potential.
Topics: Amino Acid Sequence; Animals; Antennapedia Homeodomain Protein; Carrier Proteins; Cell Line; Cell Membrane Permeability; Cell-Penetrating Peptides; Chlorocebus aethiops; Drosophila Proteins; HeLa Cells; Homeodomain Proteins; Humans; Lipid Bilayers; Membrane Potentials; Molecular Sequence Data; Nuclear Proteins; Peptide Fragments; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Protein Transport; Time Factors; Transcription Factors | 2003 |
Negative charge at amino acid 149 is the molecular determinant for substrate specificity of lecithin: cholesterol acyltransferase for phosphatidylcholine containing 20-carbon sn-2 fatty acyl chains.
Topics: Alanine; Amino Acid Substitution; Animals; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Fatty Acids; Glutamic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines; Rats; Static Electricity; Substrate Specificity | 2003 |
Conformation and self-assembly of a nystatin nitrobenzoxadiazole derivative in lipid membranes.
Topics: 4-Chloro-7-nitrobenzofurazan; Liposomes; Macromolecular Substances; Membrane Fluidity; Membrane Lipids; Molecular Conformation; Nystatin; Phosphatidylcholines; Spectrometry, Fluorescence | 2003 |
Lipid/protein interactions and the membrane/water interfacial region.
Topics: Bacterial Outer Membrane Proteins; Bacterial Proteins; Computer Simulation; Dimyristoylphosphatidylcholine; Lipid Bilayers; Models, Molecular; Phosphatidylcholines; Potassium Channels; Water | 2003 |
Pulse mode shear horizontal-surface acoustic wave (SH-SAW) system for liquid based sensing applications.
Topics: Acoustics; Biosensing Techniques; Equipment Design; Equipment Failure Analysis; Feasibility Studies; Liposomes; Phosphatidylcholines; Reproducibility of Results; Sensitivity and Specificity; Shear Strength; Solutions | 2004 |
Distribution of pentachlorophenol in phospholipid bilayers: a molecular dynamics study.
Topics: Computer Simulation; Diffusion; Lipid Bilayers; Macromolecular Substances; Membrane Fluidity; Membranes, Artificial; Models, Chemical; Models, Molecular; Molecular Conformation; Motion; Pentachlorophenol; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Surface Properties; Water | 2004 |
Enhancement of apparent substrate selectivity of proteinase K encapsulated in liposomes through a cholate-induced alteration of the bilayer permeability.
Topics: Cholates; Coated Materials, Biocompatible; Diffusion; Endopeptidase K; Enzyme Activation; Lipid Bilayers; Liposomes; Permeability; Phosphatidylcholines; Substrate Specificity | 2004 |
Destabilizing mutations promote membrane protein misfolding.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cysteine; Diacylglycerol Kinase; Enzyme Stability; Escherichia coli Proteins; Genetic Variation; Guanidine; Kinetics; Liposomes; Membrane Proteins; Micelles; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphatidylcholines; Protein Denaturation; Protein Folding; Thermodynamics | 2004 |
Conformational response of the phosphatidylcholine headgroup to bilayer surface charge: torsion angle constraints from dipolar and quadrupolar couplings in bicelles.
Topics: Carbon Isotopes; Hydrogen; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Phosphatidylglycerols; Spectrophotometry; Stress, Mechanical | 2004 |
Multi-dimensional pulsed field gradient magic angle spinning NMR experiments on membranes.
Topics: Calibration; Deuterium Oxide; Ibuprofen; Liposomes; Magnetic Resonance Spectroscopy; Membranes, Artificial; Phosphatidylcholines; Thermodynamics | 2004 |
Peptide-related alterations of membrane-associated water: deuterium solid-state NMR investigations of phosphatidylcholine membranes at different hydration levels.
Topics: Amino Acid Sequence; Animals; Brain; Deuterium; Liposomes; Magnetic Resonance Spectroscopy; Membranes, Artificial; Molecular Sequence Data; Nerve Tissue Proteins; Peptides; Phosphatidylcholines; Protein Conformation; Rats; Sodium Channels; Water | 2004 |
Dynamics of water molecules in the bacteriorhodopsin trimer in explicit lipid/water environment.
Topics: Amino Acids; Bacteriorhodopsins; Binding Sites; Computer Simulation; Dimerization; Lipid Bilayers; Membranes, Artificial; Models, Chemical; Models, Molecular; Motion; Phosphatidylcholines; Protein Binding; Protein Conformation; Water | 2004 |
Use of cyclodextrin for AFM monitoring of model raft formation.
Topics: Cholesterol; Cyclodextrins; Lipid Bilayers; Macromolecular Substances; Membrane Fluidity; Membrane Microdomains; Microscopy, Atomic Force; Molecular Conformation; Permeability; Phase Transition; Phosphatidylcholines; Sphingomyelins; Ultrasonography | 2004 |
Cholesterol superlattice modulates the activity of cholesterol oxidase in lipid membranes.
Topics: Bacterial Proteins; Catalysis; Cholesterol; Cholesterol Oxidase; Enzyme Activation; Ergosterol; Group II Phospholipases A2; Kinetics; Lipid Bilayers; Membrane Lipids; Nystatin; Phosphatidylcholines; Phospholipases A; Spectrometry, Fluorescence; Streptomyces; Substrate Specificity | 2004 |
Calorimetric measurement of phospholipid interaction with methyl-beta-cyclodextrin.
Topics: beta-Cyclodextrins; Binding Sites; Calorimetry; Cyclodextrins; Hot Temperature; Kinetics; Light; Lipid Bilayers; Models, Chemical; Phosphatidylcholines; Scattering, Radiation; Solubility; Solutions; Spectrometry, Fluorescence; Thermodynamics | 2004 |
Solid-state NMR spectroscopy of aligned lipid bilayers at low temperatures.
Topics: Cold Temperature; Deuterium; Lipid Bilayers; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Water | 2004 |
Design of a pH-sensitive pore-forming peptide with improved performance.
Topics: Amino Acid Sequence; Cholesterol; Circular Dichroism; Diiodotyrosine; Fluoresceins; Hydrogen-Ion Concentration; Liposomes; Membranes; Molecular Sequence Data; Peptides; Phosphatidylcholines; Porins; Protein Structure, Secondary | 2004 |
Cholesterol-dependent partitioning of PtdIns(4,5)P2 into membrane domains by the N-terminal fragment of NAP-22 (neuronal axonal myristoylated membrane protein of 22 kDa).
Topics: Cholesterol; Fluorescence; Hydrolysis; Lipid Bilayers; Membrane Microdomains; Membrane Proteins; Nerve Tissue Proteins; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Repressor Proteins; Spectrometry, Fluorescence; Type C Phospholipases | 2004 |
Investigating structural changes in the lipid bilayer upon insertion of the transmembrane domain of the membrane-bound protein phospholamban utilizing 31P and 2H solid-state NMR spectroscopy.
Topics: Calcium-Binding Proteins; Deuterium; Lipid Bilayers; Macromolecular Substances; Magnetic Resonance Spectroscopy; Membrane Fluidity; Membrane Proteins; Membranes; Molecular Conformation; Phosphatidylcholines; Phosphorus Isotopes; Protein Structure, Tertiary | 2004 |
Pressure-induced ordering in mixed-lipid bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Complex Mixtures; Crystallization; Dimyristoylphosphatidylcholine; Hydrostatic Pressure; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Fluidity; Molecular Conformation; Phosphatidylcholines; Phospholipids; Physical Stimulation | 2004 |
The antibacterial peptide ceratotoxin A displays alamethicin-like behavior in lipid bilayers.
Topics: Alamethicin; Animals; Anti-Bacterial Agents; Ceratitis capitata; Electric Conductivity; Insect Proteins; Lipid Bilayers; Phosphatidylcholines | 2003 |
Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled size.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cloning, Molecular; Lipid Bilayers; Nanotechnology; Phosphatidylcholines; Protein Engineering; Protein Structure, Secondary; Proteins; Scattering, Radiation; X-Rays | 2004 |
Energetics of pore formation induced by membrane active peptides.
Topics: Alamethicin; Animals; Anti-Bacterial Agents; Circular Dichroism; Ion Channels; Lipid Bilayers; Melitten; Membranes, Artificial; Models, Chemical; Phosphatidylcholines; Protein Binding; Spectroscopy, Fourier Transform Infrared; Thermodynamics; X-Ray Diffraction | 2004 |
Secondary structure and backbone dynamics of Escherichia coli diacylglycerol kinase, as revealed by site-directed solid-state 13C NMR.
Topics: Carbon Isotopes; Diacylglycerol Kinase; Escherichia coli; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Protein Structure, Secondary | 2004 |
Effects of Parkinson's disease-linked mutations on the structure of lipid-associated alpha-synuclein.
Topics: Alanine; alpha-Synuclein; Humans; Lipid Metabolism; Liposomes; Micelles; Mutation, Missense; Nerve Tissue Proteins; Nuclear Magnetic Resonance, Biomolecular; Parkinson Disease; Phosphatidic Acids; Phosphatidylcholines; Proline; Protein Binding; Protein Structure, Secondary; Recombinant Proteins; Synucleins; Threonine | 2004 |
Shape transformation of giant phospholipid vesicles at high concentrations of C12E8.
Topics: Electrochemistry; Liposomes; Membrane Fluidity; Molecular Conformation; Phase Transition; Phosphatidylcholines; Phospholipids; Polyethylene Glycols; Solutions | 2004 |
Diffusion of alpha-tocopherol in membrane models: probing the kinetics of vitamin E antioxidant action by fluorescence in real time.
Topics: alpha-Tocopherol; Antioxidants; Cell Membrane; Diffusion; Fluorescence; Kinetics; Liposomes; Micelles; Models, Biological; Molecular Structure; Octoxynol; Phosphatidylcholines; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors | 2004 |
Interfacial folding and membrane insertion of a designed helical peptide.
Topics: Buffers; Circular Dichroism; Coumarins; Hydrogen-Ion Concentration; Lipid Bilayers; Lysophospholipids; Membrane Proteins; Peptides; Phosphatidylcholines; Protein Conformation; Protein Engineering; Protein Folding; Protein Structure, Secondary; Spectrometry, Fluorescence; Surface Properties; Thermodynamics; Water | 2004 |
Influence of cholesterol and ergosterol on membrane dynamics: a fluorescence approach.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cell Membrane; Cholesterol; Ergosterol; Fluorescence Polarization; Liposomes; Membranes, Artificial; Phosphatidylcholines | 2004 |
Investigation of the membrane localization and distribution of flavonoids by high-resolution magic angle spinning NMR spectroscopy.
Topics: Antioxidants; Cell Membrane; Diffusion; Flavonoids; Magnetic Resonance Spectroscopy; Membranes, Artificial; Molecular Structure; Phosphatidylcholines | 2004 |
Perturbation of the hydrophobic core of lipid bilayers by the human antimicrobial peptide LL-37.
Topics: Antimicrobial Cationic Peptides; Calorimetry, Differential Scanning; Carbon; Cathelicidins; Cell Membrane; Dimyristoylphosphatidylcholine; Humans; Lipid Bilayers; Lipids; Magnetic Resonance Spectroscopy; Models, Statistical; Peptides; Phosphatidylcholines; Temperature | 2004 |
Structural diversity of sphingomyelin microdomains.
Topics: Lipid Bilayers; Microscopy, Atomic Force; Phosphatidylcholines; Sphingomyelins | 2004 |
Kinetics of dye efflux and lipid flip-flop induced by delta-lysin in phosphatidylcholine vesicles and the mechanism of graded release by amphipathic, alpha-helical peptides.
Topics: Fluoresceins; Fluorescent Dyes; Kinetics; Lipid Bilayers; Liposomes; Membrane Microdomains; Models, Biological; Mucoproteins; Peptides; Phosphatidylcholines; Protein Structure, Secondary | 2004 |
Surface behaviour and peptide-lipid interactions of the antibiotic peptides, Maculatin and Citropin.
Topics: Adsorption; Amphibian Proteins; Anti-Infective Agents; Antimicrobial Cationic Peptides; Hydrogen-Ion Concentration; Kinetics; Lipids; Magnetic Resonance Spectroscopy; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Thermodynamics | 2004 |
Consequences of nonlytic membrane perturbation to the translocation of the cell penetrating peptide pep-1 in lipidic vesicles.
Topics: Anions; Cell Membrane Permeability; Fluorescence Resonance Energy Transfer; Lipid Bilayers; Membrane Fusion; Membrane Potentials; Models, Chemical; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Transport; Spectrophotometry, Ultraviolet; Static Electricity | 2004 |
Solid-state NMR investigation of the selective perturbation of lipid bilayers by the cyclic antimicrobial peptide RTD-1.
Topics: alpha-Defensins; Amino Acid Sequence; Animals; Anions; Antimicrobial Cationic Peptides; Cell Membrane; Cholesterol; Dimyristoylphosphatidylcholine; Lipid Bilayers; Macaca mulatta; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Sequence Data; Peptides, Cyclic; Phosphatidylcholines; Phosphorus Isotopes; Phosphorylcholine | 2004 |
Monitoring gramicidin conformations in membranes: a fluorescence approach.
Topics: Gramicidin; Ion Channels; Liposomes; Membranes, Artificial; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 2004 |
Effect of nanomolar concentrations of sodium dodecyl sulfate, a catalytic inductor of alpha-helices, on human calcitonin incorporation and channel formation in planar lipid membranes.
Topics: Calcitonin; Catalysis; Electric Conductivity; Humans; Ion Channel Gating; Ion Channels; Lipid Bilayers; Membrane Potentials; Membranes, Artificial; Microchemistry; Nanotechnology; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Protein Structure, Secondary; Sodium Dodecyl Sulfate | 2004 |
Complementarities and convergence of results in bacteriorhodopsin trimer simulations.
Topics: Amino Acids; Bacteriorhodopsins; Binding Sites; Computer Simulation; Dimerization; Lipid Bilayers; Membranes, Artificial; Models, Chemical; Models, Molecular; Motion; Phosphatidylcholines; Protein Binding; Protein Conformation; Water | 2004 |
Scrutiny of annexin A1 mediated membrane-membrane interaction by means of a thickness shear mode resonator and computer simulations.
Topics: Adsorption; Annexin A1; Biosensing Techniques; Calcium; Computer Simulation; Gold; Membranes, Artificial; Phosphatidylcholines; Phosphatidylserines; Quartz; Sulfhydryl Compounds; Surface Properties; Time Factors | 2004 |
Cholesterol and ergosterol influence nystatin surface aggregation: relation to pore formation.
Topics: Anti-Bacterial Agents; Cholesterol; Ergosterol; Lipid Bilayers; Liposomes; Macromolecular Substances; Membrane Fluidity; Molecular Conformation; Nystatin; Phosphatidylcholines | 2004 |
Preferential interaction of dimethyl sulfoxide and phosphatidyl choline membranes.
Topics: Dimethyl Sulfoxide; Dimyristoylphosphatidylcholine; Membrane Lipids; Phosphatidylcholines; Thermodynamics | 2004 |
Molecular dynamics study of gating in the mechanosensitive channel of small conductance MscS.
Topics: Computer Simulation; Electric Conductivity; Escherichia coli Proteins; Ion Channel Gating; Ion Channels; Kinetics; Lipid Bilayers; Mechanotransduction, Cellular; Membrane Fluidity; Models, Chemical; Models, Molecular; Motion; Phosphatidylcholines; Physical Stimulation; Porosity; Protein Conformation; Stress, Mechanical; Surface Tension; Water | 2004 |
Enthalpy-driven apolipoprotein A-I and lipid bilayer interaction indicating protein penetration upon lipid binding.
Topics: Apolipoprotein A-I; Cell Membrane Permeability; Cholesterol; Circular Dichroism; Humans; Lipid Bilayers; Phosphatidylcholines; Solubility; Temperature; Thermodynamics; Titrimetry | 2004 |
Structural investigations of a human calcitonin-derived carrier peptide in a membrane environment by solid-state NMR.
Topics: Amino Acid Sequence; Calcitonin; Carbon Isotopes; Carrier Proteins; Humans; Membrane Lipids; Models, Molecular; Molecular Sequence Data; Nasal Mucosa; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Phosphorus Isotopes; Protein Conformation; Protein Structure, Secondary; Thermodynamics | 2004 |
Preliminary studies of the 2D crystallization of Omp1 of Serratia marcescens: observation by atomic force microscopy in native membranes environment and reconstituted in proteolipid sheets.
Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Ciprofloxacin; Crystallization; Dimyristoylphosphatidylcholine; Escherichia coli; Indicators and Reagents; Lipid Bilayers; Membranes; Microscopy, Atomic Force; Phosphatidylcholines; Porins; Proteolipids; Serratia marcescens | 2004 |
Membrane-bound protein in giant vesicles: induced contraction and growth.
Topics: Cell Membrane; Liposomes; Membrane Proteins; Membranes, Artificial; Phosphatidylcholines; Phosphatidylglycerols; Zein | 2004 |
An amphotericin B-fluorescein conjugate as a powerful probe for biochemical studies of the membrane.
Topics: Amines; Amphotericin B; Antifungal Agents; Cell Membrane; Electrolytes; Fluorescein; Fungi; Humans; Immunoglobulin G; Indicators and Reagents; Jurkat Cells; Microscopy, Fluorescence; Molecular Probes; Phosphatidylcholines; Piperazines; Saccharomyces cerevisiae | 2004 |
Lipid-protein interactions of integral membrane proteins: a comparative simulation study.
Topics: Bacterial Outer Membrane Proteins; Bacterial Proteins; Computer Simulation; Diffusion; Dimyristoylphosphatidylcholine; Lipid Bilayers; Membrane Fluidity; Membrane Proteins; Membranes, Artificial; Models, Chemical; Models, Molecular; Motion; Phosphatidylcholines; Potassium Channels; Protein Binding; Protein Conformation | 2004 |
Molecular dynamics simulation of transmembrane polypeptide orientational fluctuations.
Topics: Alanine; Computer Simulation; Lipid Bilayers; Lipids; Lysine; Macromolecular Substances; Magnetic Resonance Spectroscopy; Membranes, Artificial; Models, Molecular; Models, Statistical; Molecular Conformation; Nitrogen; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Temperature; Time Factors | 2005 |
High-resolution 31p field cycling NMR as a probe of phospholipid dynamics.
Topics: Cholesterol; Liposomes; Nuclear Magnetic Resonance, Biomolecular; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositols; Phospholipids; Thermodynamics | 2004 |
Glycolipid transfer protein mediated transfer of glycosphingolipids between membranes: a model for action based on kinetic and thermodynamic analyses.
Topics: Animals; Biological Transport; Carrier Proteins; Cattle; Galactosylceramides; Glycosphingolipids; Humans; Kinetics; Lipid Bilayers; Liposomes; Membrane Microdomains; Mice; Models, Chemical; Molecular Sequence Data; Phosphatidylcholines; Psychosine; Surface Properties; Swine; Temperature; Thermodynamics | 2004 |
Solid-state NMR investigation of the selective disruption of lipid membranes by protegrin-1.
Topics: Animals; Anions; Antimicrobial Cationic Peptides; Carbon Isotopes; Cholesterol; Deuterium; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phosphatidylglycerols; Phosphorus Isotopes; Proteins; Protons; Swine; Thermodynamics | 2004 |
Direct photochemical patterning and refunctionalization of supported phospholipid bilayers.
Topics: Dimyristoylphosphatidylcholine; Lipid Bilayers; Microscopy, Fluorescence; Phosphatidylcholines; Phospholipids; Photochemistry; Spectroscopy, Fourier Transform Infrared | 2004 |
Transformation diagrams for the collapse of a phospholipid monolayer.
Topics: In Vitro Techniques; Kinetics; Membrane Lipids; Membranes, Artificial; Phosphatidylcholines; Phospholipids; Thermodynamics | 2004 |
Aluminum binding to phosphatidylcholine lipid bilayer membranes: 27Al and 31P NMR spectroscopic studies.
Topics: Aluminum; Binding Sites; Lipid Bilayers; Liposomes; Macromolecular Substances; Magnetic Resonance Spectroscopy; Membranes, Artificial; Models, Chemical; Models, Molecular; Phosphatidylcholines; Phosphorus Radioisotopes | 2004 |
Binding and insertion of alpha-helical anti-microbial peptides in POPC bilayers studied by molecular dynamics simulations.
Topics: Antimicrobial Cationic Peptides; Binding Sites; Computer Simulation; Kinetics; Lipid Bilayers; Magainins; Membrane Fluidity; Membrane Proteins; Models, Chemical; Models, Molecular; Motion; Phosphatidylcholines; Protein Binding; Protein Conformation; Protein Structure, Secondary; Rabies; Xenopus Proteins | 2004 |
Influence of the lipid composition on the kinetics of concerted insertion and folding of melittin in bilayers.
Topics: Animals; Bees; Cholesterol; Kinetics; Lipid Bilayers; Melitten; Membrane Proteins; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Folding; Protein Structure, Secondary; Tryptophan | 2004 |
HIV fusion inhibitor peptide T-1249 is able to insert or adsorb to lipidic bilayers. Putative correlation with improved efficiency.
Topics: Amino Acid Sequence; Cholesterol; Enfuvirtide; Fluorescence Resonance Energy Transfer; HIV Envelope Protein gp41; Kinetics; Lipid Bilayers; Membranes, Artificial; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Thermodynamics | 2004 |
Modulation of human 5-lipoxygenase activity by membrane lipids.
Topics: Arachidonate 5-Lipoxygenase; Calcium; Cations, Divalent; Cholesterol; Diglycerides; Enzyme Activation; Glycerides; Humans; Intracellular Membranes; Kinetics; Lipid Bilayers; Membrane Lipids; Models, Chemical; Phosphatidylcholines; Quaternary Ammonium Compounds; Spectroscopy, Fourier Transform Infrared; Sphingolipids; Static Electricity; Surface Properties | 2004 |
Separation of peroxidation products of diacyl-phosphatidylcholines by reversed-phase liquid chromatography-mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Lipid Peroxidation; Oxidative Stress; Phosphatidylcholines; Spectrometry, Mass, Electrospray Ionization | 2005 |
Caveolin scaffolding region and cholesterol-rich domains in membranes.
Topics: Amino Acid Motifs; Amino Acid Sequence; Calorimetry, Differential Scanning; Caveolin 1; Caveolins; Cell Membrane; Cholesterol; Circular Dichroism; Crystallization; Crystallography, X-Ray; Fluorescence Resonance Energy Transfer; Lipids; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Spectrometry, Fluorescence; Temperature; Tryptophan | 2005 |
Tandem mass spectrometry of intact oxidation products of diacylphosphatidylcholines: evidence for the occurrence of the oxidation of the phosphocholine head and differentiation of isomers.
Topics: Isomerism; Oxidation-Reduction; Phosphatidylcholines; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship | 2004 |
The ionophore nigericin transports Pb2+ with high activity and selectivity: a comparison to monensin and ionomycin.
Topics: Cations, Divalent; Ion Transport; Ionomycin; Ionophores; Lead; Liposomes; Metals, Alkali; Metals, Alkaline Earth; Monensin; Nigericin; Phosphatidylcholines | 2004 |
2H-NMR study and molecular dynamics simulation of the location, alignment, and mobility of pyrene in POPC bilayers.
Topics: Computer Simulation; Deuterium; Lipid Bilayers; Macromolecular Substances; Magnetic Resonance Spectroscopy; Membrane Fluidity; Models, Chemical; Models, Molecular; Molecular Conformation; Motion; Phosphatidylcholines; Polycyclic Aromatic Hydrocarbons; Pyrenes; Water | 2005 |
Interfacial properties of most monofluorinated bile acids deviate markedly from the natural congeners: studies with the Langmuir-Pockels surface balance.
Topics: Air; Bile Acids and Salts; Fluorine; Models, Molecular; Phosphatidylcholines; Surface Properties; Water | 2005 |
Cardanol as a replacement for cholesterol into the lipid bilayer of POPC liposomes.
Topics: Biocompatible Materials; Cholesterol; Chromatography, High Pressure Liquid; Detergents; Ions; Kinetics; Lipid Bilayers; Lipids; Liposomes; Macromolecular Substances; Microscopy, Video; Models, Chemical; Octoxynol; Phenols; Phosphatidylcholines; Spectrophotometry; Surface-Active Agents; Temperature; Time Factors | 2005 |
A needle-and-thread approach to bilayer transport: permeation of a molecular umbrella-oligonucleotide conjugate across a phospholipid membrane.
Topics: Cell Membrane Permeability; Disulfides; Drug Carriers; Glutathione; Lipid Bilayers; Models, Molecular; Oligonucleotides; Phosphatidylcholines; Phosphatidylglycerols | 2005 |
Plasma factors required for human apolipoprotein A-II dimerization.
Topics: Apolipoprotein A-II; Carrier Proteins; Dimerization; Disulfides; Guanidine; Humans; Kinetics; Lipid Bilayers; Lipoproteins, HDL; Models, Chemical; Phosphatidylcholines; Protein Denaturation; Protein Structure, Secondary; Serum Albumin | 2005 |
The 3-hydroxy group and 4,5-trans double bond of sphingomyelin are essential for modulation of galactosylceramide transmembrane asymmetry.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Biophysics; Chickens; Galactosylceramides; Lipid Bilayers; Lipids; Magnetic Resonance Spectroscopy; Membrane Microdomains; Models, Molecular; Nitrogen; Ovum; Oxygen; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Sphingolipids; Sphingomyelins | 2005 |
Determination of the activation volume of PLCbeta by Gbeta gamma-subunits through the use of high hydrostatic pressure.
Topics: Animals; Baculoviridae; Biophysics; Buffers; Calcium; Cell Line; Dose-Response Relationship, Drug; Fluorescence Resonance Energy Transfer; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Insecta; Isoenzymes; Lipid Bilayers; Lipids; Macromolecular Substances; Membranes; Models, Biological; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase C beta; Pressure; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Proteins; Signal Transduction; Spectrometry, Fluorescence; Thermodynamics; Type C Phospholipases | 2005 |
Formation of supported phospholipid bilayers via co-adsorption with beta-D-dodecyl maltoside.
Topics: Adsorption; Cryoelectron Microscopy; Glucosides; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Micelles; Phosphatidylcholines; Phospholipids | 2005 |
Atomic force microscopy study of Escherichia coli lactose permease proteolipid sheets.
Topics: Adsorption; Biosensing Techniques; Coated Materials, Biocompatible; Enzymes, Immobilized; Escherichia coli; Escherichia coli Proteins; Materials Testing; Membranes, Artificial; Microscopy, Atomic Force; Monosaccharide Transport Proteins; Phosphatidylcholines; Protein Binding; Surface Properties; Symporters | 2005 |
Molecular dynamics simulations of unsaturated lipid bilayers: effects of varying the numbers of double bonds.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Carbon; Computer Simulation; Glycerol; Lipid Bilayers; Lipids; Macromolecular Substances; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Models, Statistical; Models, Theoretical; Molecular Conformation; Oxygen; Phosphatidylcholines; Phospholipids; Pressure; Protein Binding; Protein Conformation; Software; Static Electricity; Time Factors | 2005 |
Role of sterol superlattice in free radical-induced sterol oxidation in lipid membranes.
Topics: Amidines; Animals; Brain Chemistry; Cattle; Cholesterol; Ergosterol; Fluorometry; Free Radicals; Kinetics; Light; Lipid Bilayers; Lipid Peroxidation; Phosphatidylcholines; Scattering, Radiation; Spectrophotometry; Sphingomyelins; Sterols | 2005 |
Isothermal titration calorimetry studies of the binding of a rationally designed analogue of the antimicrobial peptide gramicidin s to phospholipid bilayer membranes.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Calorimetry; Cholesterol; Drug Design; Gramicidin; Lipid Bilayers; Models, Chemical; Molecular Sequence Data; Peptides, Cyclic; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Phospholipids; Protein Binding; Static Electricity; Stereoisomerism; Thermodynamics; Titrimetry | 2005 |
Binding of oligoarginine to membrane lipids and heparan sulfate: structural and thermodynamic characterization of a cell-penetrating peptide.
Topics: Animals; Anions; Arginine; Calorimetry; Cell Membrane Permeability; Deuterium Exchange Measurement; Heparitin Sulfate; Light; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Chemical; Oligopeptides; Phosphatidylcholines; Phosphatidylglycerols; Phosphorus Isotopes; Protein Binding; Scattering, Radiation; Static Electricity; Swine; Thermodynamics | 2005 |
Spontaneous immobilization of liposomes on electron-beam exposed resist surfaces.
Topics: Liposomes; Microscopy, Atomic Force; Phosphatidylcholines; Phosphatidylglycerols; Surface Properties | 2005 |
Water molecules and hydrogen-bonded networks in bacteriorhodopsin--molecular dynamics simulations of the ground state and the M-intermediate.
Topics: Bacteriorhodopsins; Biological Transport; Biophysics; Computer Simulation; Crystallography, X-Ray; Diffusion; Dimerization; Halobacterium; Hydrogen Bonding; Models, Chemical; Models, Molecular; Models, Statistical; Phosphatidylcholines; Protein Conformation; Protein Structure, Tertiary; Protons; Software; Time Factors; Water | 2005 |
Reversible transition between the surface trimer and membrane-inserted monomer of annexin 12.
Topics: Animals; Annexins; Calcium; Cysteine; Fluorescence Resonance Energy Transfer; Hydra; Membrane Lipids; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Protein Conformation; Spectrometry, Fluorescence; Surface Properties; Thermodynamics | 2005 |
Feasibility of tracking phospholipid permeation into skin using infrared and Raman microscopic imaging.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Deuterium; Feasibility Studies; Liposomes; Membrane Fluidity; Phosphatidylcholines; Phospholipids; Skin; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Swine | 2005 |
Imaging chirality with surface second harmonic generation microscopy.
Topics: Lipid Bilayers; Microscopy; Naphthols; Optics and Photonics; Phosphatidylcholines; Stereoisomerism | 2005 |
Surface thermodynamics study of monolayers formed with heteroacid phospholipids of biological interest.
Topics: Air; Hydrogen Bonding; Liposomes; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Surface Properties; Thermodynamics; Water | 2005 |
Lipidic membranes are potential "catalysts" in the ligand activity of the multifunctional pentapeptide neokyotorphin.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Algorithms; Cholesterol; Endorphins; Ligands; Lipid Bilayers; Liposomes; Models, Molecular; Opioid Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics | 2005 |
Phospholipase D-mediated aggregation, fusion, and precipitation of phospholipid vesicles.
Topics: Calcium; Cations, Divalent; Chemical Precipitation; Chymotrypsinogen; Lipid Bilayers; Membrane Fusion; Microscopy, Electron; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phospholipids; Temperature; Time Factors; Trypsin | 2004 |
Determination of peptide oligomerization in lipid bilayers using 19F spin diffusion NMR.
Topics: Anti-Infective Agents; Antimicrobial Cationic Peptides; Dimerization; Fluorine; Glycine; Lipid Bilayers; Membrane Proteins; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phenylalanine; Phosphatidylcholines; Proteins; Thermodynamics | 2005 |
Controlling association of vesicle embedded peptides by alteration of the physical state of the lipid matrix.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Amino Acid Sequence; Chemical Phenomena; Chemistry, Physical; Fluorescence Resonance Energy Transfer; In Vitro Techniques; Lipid Bilayers; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Thermodynamics | 2005 |
Interaction of human apolipoprotein A-I with model membranes exhibiting lipid domains.
Topics: Apolipoprotein A-I; Calorimetry; Cholesterol; Circular Dichroism; Hot Temperature; Humans; Kinetics; Lipid Bilayers; Lipids; Microscopy, Fluorescence; Phosphatidylcholines; Photons; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sphingomyelins; Temperature; Thermodynamics | 2005 |
The behaviour of beta-carotene in the phosphatidylcholine bilayer as revealed by a molecular simulation study.
Topics: beta Carotene; Computer Simulation; Lipid Bilayers; Macromolecular Substances; Membrane Fluidity; Models, Chemical; Models, Molecular; Molecular Conformation; Phase Transition; Phosphatidylcholines | 2005 |
The effect of cholesterol on the solubilization of phosphatidylcholine bilayers by the non-ionic surfactant Triton X-100.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Ions; Lipid Bilayers; Liposomes; Membrane Fluidity; Octoxynol; Particle Size; Phase Transition; Phosphatidylcholines; Solubility; Surface-Active Agents; Temperature | 2005 |
A gating mechanism proposed from a simulation of a human alpha7 nicotinic acetylcholine receptor.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Binding Sites; Carbon; Computer Simulation; Crystallography, X-Ray; Cysteine; Humans; Kinetics; Ligands; Lipid Bilayers; Models, Molecular; Phosphatidylcholines; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Receptors, Nicotinic; Software | 2005 |
Thermally gated liposomes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Drug Delivery Systems; Fluoresceins; Kinetics; Lipid Bilayers; Liposomes; Phosphatidylcholines; Spermine; Temperature | 2005 |
Phospholipid morphologies on photochemically patterned silane monolayers.
Topics: Adsorption; Dimyristoylphosphatidylcholine; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Lipid Bilayers; Membrane Fluidity; Microscopy, Fluorescence; Phosphatidylcholines; Phospholipids; Photobleaching; Serum Albumin, Bovine; Silanes; Streptavidin | 2005 |
Detergent-like properties of magainin antibiotic peptides: a 31P solid-state NMR spectroscopy study.
Topics: Anisotropy; Circular Dichroism; Detergents; Dimyristoylphosphatidylcholine; Lipid Bilayers; Magnetic Resonance Spectroscopy; Micelles; Models, Biological; Peptides; Phosphatidylcholines; Phosphatidylinositols; Phosphatidylserines; Phosphorus Isotopes; Spectroscopy, Fourier Transform Infrared; Temperature | 2005 |
Protein mediated glycolipid transfer is inhibited FROM sphingomyelin membranes but enhanced TO sphingomyelin containing raft like membranes.
Topics: Animals; Brain; Carrier Proteins; Cattle; Cholesterol; Fluorescent Dyes; Glycosphingolipids; Liposomes; Membrane Microdomains; Phosphatidylcholines; Phospholipids; Sphingomyelins; Temperature | 2005 |
Raman spectra of planar supported lipid bilayers.
Topics: Androstanes; Dimyristoylphosphatidylcholine; Lipid Bilayers; Phase Transition; Phosphatidylcholines; Spectrum Analysis, Raman; Temperature | 2005 |
Bilayer interaction and localization of cell penetrating peptides with model membranes: a comparative study of a human calcitonin (hCT)-derived peptide with pVEC and pAntp(43-58).
Topics: Acrylamide; Amino Acid Sequence; Antigens, CD; Biochemical Phenomena; Biochemistry; Cadherins; Calcitonin; Cell Membrane; Humans; Kinetics; Light; Lipid Bilayers; Lipids; Liposomes; Micelles; Microscopy, Fluorescence; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phospholipids; Scattering, Radiation; Spectrometry, Fluorescence; Temperature | 2005 |
Interactions of cholesterol with lipid membranes and cyclodextrin characterized by calorimetry.
Topics: Calorimetry; Cholesterol; Computer Simulation; Cyclodextrins; Lipid Bilayers; Membrane Fluidity; Membrane Microdomains; Models, Chemical; Phase Transition; Phosphatidylcholines; Thermodynamics | 2005 |
Hydroxide and proton migration in aquaporins.
Topics: Alanine; Amino Acid Motifs; Aquaporins; Asparagine; Biological Transport; Biophysics; Cytoplasm; Escherichia coli; Escherichia coli Proteins; Hydrogen; Hydrogen Bonding; Hydroxides; Ions; Lipid Bilayers; Models, Chemical; Models, Molecular; Oxygen; Periplasm; Phosphatidylcholines; Proline; Protons; Static Electricity; Time Factors; Water | 2005 |
In situ sensing of salinity in oriented lipid multilayers by surface X-ray scattering.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Kinetics; Lipids; Lithium Chloride; Phosphatidylcholines; Scattering, Radiation; Solutions; Temperature; X-Ray Diffraction; X-Rays | 2004 |
Effects of the sugar headgroup of a glycoglycerolipid on the phase behavior of phospholipid model membranes in the dry state.
Topics: Carbohydrates; Galactolipids; Glycolipids; Hydrogen Bonding; Membranes, Artificial; Models, Chemical; Phosphatidylcholines; Phospholipids; Spectroscopy, Fourier Transform Infrared; Surface Properties; Temperature | 2005 |
GPI-alkaline phosphatase insertion into phosphatidylcholine monolayers: phase behavior and morphology changes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Adsorption; Alkaline Phosphatase; Animals; Cattle; Compressive Strength; Glycosylphosphatidylinositols; Intestinal Mucosa; Lipid Bilayers; Macromolecular Substances; Membrane Fluidity; Phase Transition; Phosphatidylcholines; Protein Binding; Protein Conformation; Surface Properties | 2005 |
Persistence of metastability after expansion of a supercompressed fluid monolayer.
Topics: Phosphatidylcholines; Pressure; Rheology | 2004 |
Direct visualization of membrane leakage induced by the antibiotic peptides: maculatin, citropin, and aurein.
Topics: Amphibian Proteins; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Cell Membrane; Fluoresceins; Lipid Bilayers; Lipids; Membrane Lipids; Membranes; Microscopy, Confocal; Microscopy, Fluorescence; Mutagenesis; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Ranidae; Time Factors | 2005 |
Permeabilization of raft-containing lipid vesicles by delta-lysin: a mechanism for cell sensitivity to cytotoxic peptides.
Topics: Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides; Bacterial Proteins; Cell Membrane Permeability; Cholesterol; Fluoresceins; Hemolysin Proteins; Lipid Bilayers; Membrane Microdomains; Models, Chemical; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Binding; Protein Transport; Sphingomyelins; Staphylococcus aureus; Swine | 2005 |
Application of quantitative structure activity relationship (QSAR) models to predict ozone toxicity in the lung.
Topics: Cell Line; Enzyme Activation; Epithelial Cells; Humans; Lung; Models, Biological; Molecular Structure; Ozone; Phosphatidylcholines; Phospholipases; Quantitative Structure-Activity Relationship | 2005 |
A spectroscopic study of the membrane interaction of tuberoinfundibular peptide of 39 residues (TIP39).
Topics: Animals; Cattle; Cholesterol; Membranes, Artificial; Micelles; Neuropeptides; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phosphatidylserines; Receptor, Parathyroid Hormone, Type 2; Spectrometry, Fluorescence | 2005 |
Surface thermodynamic properties of monolayers versus reconstitution of a membrane protein in solid-supported bilayers.
Topics: Adsorption; Air; Dimyristoylphosphatidylcholine; Escherichia coli; Hot Temperature; Lipid Bilayers; Liposomes; Membrane Transport Proteins; Microscopy, Atomic Force; Models, Statistical; Phosphatidylcholines; Phospholipids; Pressure; Surface Properties; Thermodynamics; Water | 2005 |
Translocation of beta-galactosidase mediated by the cell-penetrating peptide pep-1 into lipid vesicles and human HeLa cells is driven by membrane electrostatic potential.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Amino Acid Sequence; beta-Galactosidase; Cell Membrane; Cell Membrane Permeability; Cholesterol, HDL; Cysteamine; Dextrans; Endosomes; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Liposomes; Membrane Potentials; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Transport; Solutions; Static Electricity; Water | 2005 |
Solid-state nuclear magnetic resonance relaxation studies of the interaction mechanism of antimicrobial peptides with phospholipid bilayer membranes.
Topics: Amino Acid Sequence; Antimicrobial Cationic Peptides; Deuterium; Hydrophobic and Hydrophilic Interactions; Isotope Labeling; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Phosphorus Isotopes; Protein Structure, Secondary; Thermodynamics | 2005 |
Using the intrinsic chirality of a molecule as a label-free probe to detect molecular adsorption to a surface by second harmonic generation.
Topics: Adsorption; Algorithms; Binding Sites; Isomerism; Kinetics; Lipid Bilayers; Molecular Probe Techniques; Naphthols; Phosphatidylcholines; Refractometry; Spectrum Analysis | 2005 |
Interaction of cetylpyridinium chloride with giant lipid vesicles.
Topics: Cations; Cetylpyridinium; Fluorescence; Lipids; Micelles; Phosphatidylcholines; Potentiometry; Pyrenes; Sensitivity and Specificity; Surface-Active Agents | 2005 |
Shape relaxations in a fluid supported membrane during hydrolysis by phospholipase A(2).
Topics: Carbocyanines; Hydrolysis; Lipid Bilayers; Membrane Fluidity; Microscopy, Fluorescence; Phosphatidylcholines; Phospholipases A | 2005 |
Preliminary atomic force microscopy study of two-dimensional crystals of lactose permease from Escherichia coli.
Topics: Crystallization; Dimerization; Escherichia coli; Fourier Analysis; Liposomes; Membrane Transport Proteins; Microscopy, Atomic Force; Phosphatidylcholines; Protein Conformation; Proteolipids | 2006 |
Formation of reactive halide species by myeloperoxidase and eosinophil peroxidase.
Topics: Alcohols; Chlorohydrins; Computer Simulation; Eosinophil Peroxidase; Halogens; Hydrogen Peroxide; Hydrogen-Ion Concentration; Models, Chemical; Oxidation-Reduction; Peroxidase; Phosphatidylcholines; Thermodynamics | 2006 |
Molecular dynamics simulation of human neurohypophyseal hormone receptors complexed with oxytocin-modeling of an activated state.
Topics: Amino Acid Sequence; Animals; Cattle; Computer Simulation; Humans; Ligands; Models, Chemical; Molecular Sequence Data; Oxytocin; Phosphatidylcholines; Protein Conformation; Protein Structure, Tertiary; Receptors, Oxytocin; Receptors, Vasopressin; Sequence Alignment | 2006 |
Poly(choloyl)-based amphiphiles as pore-forming agents: transport-active monomers by design.
Topics: Carbohydrate Sequence; Cholic Acids; Kinetics; Lysine; Molecular Sequence Data; Molecular Structure; Phenylenediamines; Phosphatidylcholines; Polymers; Sodium; Structure-Activity Relationship; Surface-Active Agents; Time Factors | 2005 |
Peripheral protein adsorption to lipid-water interfaces: the free area theory.
Topics: Adsorption; Binding Sites; Computer Simulation; Lipid Bilayers; Membrane Fluidity; Membrane Proteins; Models, Chemical; Models, Molecular; Phosphatidylcholines; Protein Binding; Water | 2005 |
Interfacial tryptophan residues: a role for the cation-pi effect?
Topics: Amino Acids; Cations; Computer Simulation; Lipid Bilayers; Membrane Fluidity; Membrane Proteins; Models, Chemical; Models, Molecular; Phosphatidylcholines; Phosphatidylethanolamines; Protein Conformation; Tryptophan; Water | 2005 |
Comparison of surfactant lipids between pleural and pulmonary lining fluids.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Body Fluids; Bronchoalveolar Lavage Fluid; Cats; Female; Leukocytes; Male; Phosphatidylcholines; Phospholipids; Pleura; Pleural Cavity; Pulmonary Surfactants | 2006 |
Properties and structures of the influenza and HIV fusion peptides on lipid membranes: implications for a role in fusion.
Topics: Amino Acid Sequence; Anisotropy; Cell Membrane; Chloroform; Circular Dichroism; Dose-Response Relationship, Drug; Hemagglutinin Glycoproteins, Influenza Virus; HIV Envelope Protein gp41; Lipid Bilayers; Lipids; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides; Phosphatidylcholines; Polyethylene Glycols; Protein Structure, Secondary; Recombinant Fusion Proteins; Spectrophotometry, Infrared; Tryptophan; Water | 2005 |
Effect of tryptophan oligopeptides on the size distribution of POPC liposomes: a dynamic light scattering and turbidimetric study.
Topics: Indoles; Light; Liposomes; Nephelometry and Turbidimetry; Oligopeptides; Particle Size; Phosphatidylcholines; Tryptophan | 2005 |
Lysolipid incorporation in dipalmitoylphosphatidylcholine bilayer membranes enhances the ion permeability and drug release rates at the membrane phase transition.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Biophysics; Calorimetry; Calorimetry, Differential Scanning; Dithionite; Doxorubicin; Ions; Lipid Bilayers; Lipids; Liposomes; Mass Spectrometry; Membranes, Artificial; Models, Chemical; Permeability; Phosphatidylcholines; Spectrophotometry; Temperature; Time Factors | 2005 |
Impact of membrane cholesterol content on the resistance of vesicles to surfactant attack.
Topics: Animals; Cholestanol; Cholesterol; Detergents; Dose-Response Relationship, Drug; Membranes; Phosphatidylcholines; Phospholipids; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Spermatocidal Agents; Sterols; Surface-Active Agents; Time Factors | 2005 |
Effects of lactose permease of Escherichia coli on the anisotropy and electrostatic surface potential of liposomes.
Topics: Anisotropy; Benzenesulfonates; Dimyristoylphosphatidylcholine; Diphenylhexatriene; Escherichia coli; Fluorescent Dyes; Lipids; Liposomes; Membrane Transport Proteins; Models, Biological; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Static Electricity; Temperature | 2006 |
The mechanism of membrane targeting of human sphingosine kinase 1.
Topics: Amino Acid Sequence; Asparagine; Cell Line; Cell Membrane; DNA Mutational Analysis; Green Fluorescent Proteins; Humans; Kinetics; Lipids; Lysophospholipids; Mass Spectrometry; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Molecular Sequence Data; Mutation; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Pressure; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Sphingosine; Surface Plasmon Resonance; Threonine; Time Factors; Transfection | 2005 |
Two tail-anchored protein variants, differing in transmembrane domain length and intracellular sorting, interact differently with lipids.
Topics: Amino Acid Sequence; Calorimetry, Differential Scanning; Cell Membrane; Cytochromes b5; Fluorescence; Lipid Bilayers; Lipids; Liposomes; Molecular Sequence Data; Phosphatidylcholines; Protein Structure, Tertiary | 2005 |
Effect of temperature, cholesterol content, and antioxidant structure on the mobility of vitamin E constituents in biomembrane models studied by laterally diffusion-controlled fluorescence quenching.
Topics: Antioxidants; Cholesterol; Diffusion; Fluorescence; Liposomes; Phosphatidylcholines; Temperature; Tocopherols; Tocotrienols; Vitamin E | 2005 |
The biotin-capture lipid affinity assay: a rapid method for determining lipid binding parameters for apolipoproteins.
Topics: Algorithms; Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins; Apolipoproteins A; Bacterial Proteins; Benzoates; Biotin; Chromatography, Affinity; Dansyl Compounds; Humans; Liposomes; Mutation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Binding; Quinolines; Recombinant Proteins; Reproducibility of Results; Rhodamines; Sepharose; Spectrometry, Fluorescence | 2006 |
Molecular umbrella-assisted transport of an oligonucleotide across cholesterol-rich phospholipid bilayers.
Topics: Biological Transport; Cholesterol; Cholic Acid; Deoxycholic Acid; Lipid Bilayers; Liposomes; Lysine; Models, Molecular; Nitrobenzoates; Oligonucleotides; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Spermidine; Structure-Activity Relationship; Sulfhydryl Compounds | 2005 |
Multilamellarity, structure and hydration of extruded POPC vesicles by SANS.
Topics: Lipid Bilayers; Liposomes; Models, Chemical; Neutron Diffraction; Phase Transition; Phosphatidylcholines; Scattering, Small Angle; Water | 2006 |
Structure and lipid interaction of N-palmitoylsphingomyelin in bilayer membranes as revealed by 2H-NMR spectroscopy.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Biophysics; Hydrogen Bonding; Lipid Bilayers; Lipids; Magnetic Resonance Spectroscopy; Molecular Conformation; Phosphatidylcholines; Protein Structure, Tertiary; Spectrophotometry; Sphingomyelins; Temperature | 2006 |
Phosphatidylserine membrane domain clustering induced by annexin A2/S100A10 heterotetramer.
Topics: Annexin A2; Lipid Bilayers; Microscopy, Atomic Force; Microscopy, Fluorescence; Phosphatidylcholines; Phosphatidylserines; Protein Structure, Quaternary; Protein Structure, Tertiary; S100 Proteins | 2005 |
Why are HIV-1 fusion inhibitors not effective against SARS-CoV? Biophysical evaluation of molecular interactions.
Topics: Amino Acid Sequence; Enfuvirtide; HIV Envelope Protein gp41; HIV Fusion Inhibitors; Hydrophobic and Hydrophilic Interactions; Liposomes; Peptide Fragments; Phosphatidylcholines; Severe acute respiratory syndrome-related coronavirus; Viral Fusion Proteins | 2006 |
A silicate gel for promoting deposition of lipid bilayers.
Topics: Adsorption; Gels; Lipid Bilayers; Phosphatidylcholines; Polymethyl Methacrylate; Silicates | 2002 |
Partially reversible adsorption of annexin A1 on POPC/POPS bilayers investigated by QCM measurements, SFM, and DMC simulations.
Topics: Adsorption; Annexin A1; Biosensing Techniques; Computer Simulation; Lipid Bilayers; Membranes, Artificial; Microscopy, Atomic Force; Microscopy, Fluorescence; Monte Carlo Method; Particle Size; Phosphatidylcholines; Phosphatidylserines; Stress, Mechanical; Surface Properties; Time Factors | 2006 |
ApoA-I/phosphatidylcholine discs remodels fast-migrating HDL into slow-migrating HDL as characterized by capillary isotachophoresis.
Topics: Apolipoprotein A-I; Electrophoresis, Capillary; High-Density Lipoproteins, Pre-beta; Humans; Lecithin Cholesterol Acyltransferase Deficiency; Lipoproteins, HDL; Monitoring, Physiologic; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines | 2006 |
Under the influence of alcohol: the effect of ethanol and methanol on lipid bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Computer Simulation; Ethanol; Hydrogen Bonding; Lipid Bilayers; Magnetic Resonance Spectroscopy; Methanol; Models, Molecular; Phosphatidylcholines; Static Electricity; Water | 2006 |
Universal behavior of membranes with sterols.
Topics: Compressive Strength; Elasticity; Lipid Bilayers; Membrane Fluidity; Models, Chemical; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Sterols; Stress, Mechanical | 2006 |
The effects of temperature, pressure and peptide incorporation on ternary model raft mixtures--a Laurdan fluorescence spectroscopy study.
Topics: 2-Naphthylamine; Cholesterol; Fluorescence Polarization; Gramicidin; Laurates; Membrane Microdomains; Molecular Conformation; Peptides; Phosphatidylcholines; Pressure; Spectrometry, Fluorescence; Sphingomyelins; Temperature | 2006 |
Investigation of mechanism of desmopressin binding in vasopressin V2 receptor versus vasopressin V1a and oxytocin receptors: molecular dynamics simulation of the agonist-bound state in the membrane-aqueous system.
Topics: Amino Acid Motifs; Biopolymers; Cell Membrane; Computer Simulation; Conserved Sequence; Deamino Arginine Vasopressin; GTP-Binding Proteins; Humans; Ligands; Models, Molecular; Molecular Conformation; Mutation; Oxytocin; Peptides; Phosphatidylcholines; Protein Binding; Protein Conformation; Receptors, Oxytocin; Receptors, Vasopressin; Water | 2006 |
The antibiotic and DNA-transfecting peptide LAH4 selectively associates with, and disorders, anionic lipids in mixed membranes.
Topics: Amino Acid Sequence; Anions; Antimicrobial Cationic Peptides; Cell Line; Cholesterol; DNA; Humans; Hydrogen-Ion Concentration; Membrane Lipids; Membranes, Artificial; Peptides; Phosphatidylcholines; Phosphatidylserines; Substrate Specificity; Transfection | 2006 |
Lipid membrane interaction and antimicrobial activity of GsMTx-4, an inhibitor of mechanosensitive channel.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Calcium; Chromatography, High Pressure Liquid; Gram-Negative Bacteria; Gram-Positive Bacteria; Intercellular Signaling Peptides and Proteins; Ion Channel Gating; Ion Channels; Mechanoreceptors; Membrane Lipids; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Tertiary; Spider Venoms; Structure-Activity Relationship; Toxins, Biological | 2006 |
A class of supported membranes: formation of fluid phospholipid bilayers on photonic band gap colloidal crystals.
Topics: Colloids; Fluorescence Recovery After Photobleaching; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Phosphatidylcholines; Phospholipids; Silicon Dioxide; Xanthenes | 2006 |
Visualizing association of N-ras in lipid microdomains: influence of domain structure and interfacial adsorption.
Topics: Boron Compounds; Cholesterol; Fluorescent Dyes; Membrane Lipids; Membrane Microdomains; Microscopy, Atomic Force; Microscopy, Fluorescence; Models, Molecular; Phosphatidylcholines; ras Proteins; Sphingomyelins | 2006 |
Infrared surface plasmon resonance: a novel tool for real time sensing of variations in living cells.
Topics: alpha-Cyclodextrins; Biosensing Techniques; Cells, Cultured; Cholesterol; Circular Dichroism; Cyclodextrins; Electrochemistry; HeLa Cells; Humans; Lipids; Microscopy, Electron; Phosphatidylcholines; Phospholipids; Refractometry; Spectroscopy, Fourier Transform Infrared; Surface Plasmon Resonance; Time Factors | 2006 |
Single-channel water permeabilities of Escherichia coli aquaporins AqpZ and GlpF.
Topics: Aquaporins; Biophysics; Carbohydrate Metabolism; Computer Simulation; Crystallography, X-Ray; Databases, Protein; Diffusion; Escherichia coli; Escherichia coli Proteins; Histidine; Kinetics; Lipid Bilayers; Membrane Proteins; Models, Molecular; Models, Statistical; Models, Theoretical; Osmosis; Permeability; Phosphatidylcholines; Phosphatidylethanolamines; Protons; Static Electricity; Time Factors; Water | 2006 |
Amyloid-beta peptide disruption of lipid membranes and the effect of metal ions.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Cations, Divalent; Circular Dichroism; Copper; Humans; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Lipids; Membrane Microdomains; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Phosphatidylserines; Spectrometry, Fluorescence; Zinc | 2006 |
Interaction of hypohalous acids and heme peroxidases with unsaturated phosphatidylcholines.
Topics: Alcohols; Bromides; Chlorides; Hydrogen Peroxide; Hypochlorous Acid; Iodides; Oxidation-Reduction; Peroxidase; Phosphatidylcholines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiocyanates | 2005 |
Surface planar bilayers of phospholipids used in protein membrane reconstitution: an atomic force microscopy study.
Topics: Dimyristoylphosphatidylcholine; Escherichia coli; Lipid Bilayers; Liposomes; Membrane Proteins; Microscopy, Atomic Force; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Surface Properties; Thermodynamics | 2006 |
Searching for the molecular arrangement of transmembrane ceramide channels.
Topics: Apoptosis; Cell Membrane; Ceramides; Computer Simulation; Cytochromes c; Hydrogen; Hydrogen Bonding; Ions; Lipid Bilayers; Mitochondria; Mitochondrial Membranes; Models, Chemical; Models, Molecular; Models, Statistical; Molecular Conformation; Palmitic Acid; Phosphatidylcholines; Phospholipids; Protein Conformation; Static Electricity; Time Factors; Water | 2006 |
Molecular dynamics studies of the archaeal translocon.
Topics: Alanine; Archaea; Archaeal Proteins; Asparagine; Biophysics; Computer Simulation; Cytoplasm; Databases, Protein; Dimerization; Glycine; Histidine; Hydrogen; Ions; Leucine; Lipid Bilayers; Lipids; Methanococcus; Models, Molecular; Molecular Conformation; Oligopeptides; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Transport; Reproducibility of Results; Static Electricity; Time Factors; Water | 2006 |
Monitoring lipid membrane translocation of sodium dodecyl sulfate by isothermal titration calorimetry.
Topics: Calorimetry; Lipid Bilayers; Phosphatidylcholines; Sodium Dodecyl Sulfate; Solubility; Static Electricity; Temperature; Thermodynamics | 2006 |
Self-adhesion among phospholipid vesicles.
Topics: Cell Adhesion; Dimerization; Hydrogen Bonding; Lipid Bilayers; Phosphatidylcholines; Pyrimidinones | 2006 |
Zero mode waveguides for single-molecule spectroscopy on lipid membranes.
Topics: Gangliosides; Lipid Bilayers; Models, Biological; Nanostructures; Phosphatidylcholines; Spectrometry, Fluorescence; Tetanus Toxin | 2006 |
Interactions of Bax and tBid with lipid monolayers.
Topics: Animals; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Calcium; Cardiolipins; Cattle; Humans; Lipid Metabolism; Phosphatidylcholines; Phosphatidylethanolamines; Protein Structure, Tertiary | 2005 |
Interfacial properties of the M1 segment of the nicotinic acetylcholine receptor.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Adsorption; Amino Acid Sequence; Cell Membrane; Computer Simulation; Micelles; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Protein Subunits; Receptors, Nicotinic; Sodium Dodecyl Sulfate; Spectroscopy, Fourier Transform Infrared; Surface Properties; Thermodynamics; Water | 2006 |
Adsorption of DNA and electric fields decrease the rigidity of lipid vesicle membranes.
Topics: Adsorption; Animals; Cattle; DNA; Lipids; Membranes, Artificial; Phosphatidylcholines; Static Electricity; Thermodynamics; Transport Vesicles | 2005 |
Selective transport of Pb2+ and Cd2+ across a phospholipid bilayer by a cyclohexanemonocarboxylic acid-capped 15-crown-5 ether.
Topics: Cadmium; Cations, Divalent; Crown Ethers; Cyclohexanecarboxylic Acids; Hydrogen-Ion Concentration; Ion Transport; Ionomycin; Ionophores; Kinetics; Lead; Membrane Potentials; Membranes, Artificial; Molecular Structure; Monensin; Phosphatidylcholines | 2006 |
Quantitative multiplex CARS spectroscopy in congested spectral regions.
Topics: Adenosine Triphosphate; NAD; Phosphatidylcholines; Spectrum Analysis, Raman; Vibration; Water | 2006 |
Proton permeation into single vesicles occurs via a sequential two-step mechanism and is heterogeneous.
Topics: Cell Membrane Permeability; Fluoresceins; Fluorescent Dyes; Kinetics; Liposomes; Microfluidic Analytical Techniques; Microscopy, Fluorescence; Phosphatidylcholines; Protons | 2006 |
Temperature and pressure effects on structural and conformational properties of POPC/SM/cholesterol model raft mixtures--a FT-IR, SAXS, DSC, PPC and Laurdan fluorescence spectroscopy study.
Topics: 2-Naphthylamine; Animals; Calorimetry; Calorimetry, Differential Scanning; Cattle; Cholesterol; Fluorescent Dyes; Laurates; Membrane Microdomains; Molecular Conformation; Phosphatidylcholines; Pressure; Scattering, Radiation; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Sphingomyelins; Synchrotrons; Temperature; X-Rays | 2006 |
The membranes' role in the HIV-1 neutralizing monoclonal antibody 2F5 mode of action needs re-evaluation.
Topics: Amino Acids, Aromatic; Antibodies, Monoclonal; Epitopes; Fluorescent Dyes; Fluorometry; HIV Infections; HIV-1; Humans; Immunotherapy; Membranes; Phosphatidylcholines; Pyridinium Compounds | 2006 |
Thermodynamic and structural study of the main phospholipid components comprising the mitochondrial inner membrane.
Topics: Cardiolipins; In Vitro Techniques; Intracellular Membranes; Lipid Bilayers; Membrane Lipids; Microscopy, Atomic Force; Mitochondria; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Thermodynamics | 2006 |
Absence of fluid-ordered/fluid-disordered phase coexistence in ceramide/POPC mixtures containing cholesterol.
Topics: Ceramides; Cholesterol; Computer Simulation; Lipid Bilayers; Liposomes; Membrane Fluidity; Membranes, Artificial; Models, Chemical; Models, Molecular; Phase Transition; Phosphatidylcholines; Solutions | 2006 |
Thermodynamics of lipid membrane solubilization by sodium dodecyl sulfate.
Topics: Lipid Bilayers; Liposomes; Membrane Fluidity; Membranes, Artificial; Molecular Conformation; Phase Transition; Phosphatidylcholines; Sodium Dodecyl Sulfate; Solubility; Temperature; Thermodynamics | 2006 |
Thermodynamic comparison of the interactions of cholesterol with unsaturated phospholipid and sphingomyelins.
Topics: Cholesterol; Lipid Bilayers; Liposomes; Membrane Fluidity; Molecular Conformation; Phosphatidylcholines; Sphingomyelins; Thermodynamics | 2006 |
Identification of membrane-contacting loops of the catalytic domain of cytochrome P450 2C2 by tryptophan fluorescence scanning.
Topics: Catalytic Domain; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Liposomes; Membrane Proteins; Models, Molecular; Mutagenesis, Site-Directed; Phosphatidylcholines; Spectrometry, Fluorescence; Spin Labels; Tryptophan | 2006 |
Translocation of phospholipids and dithionite permeability in liquid-ordered and liquid-disordered membranes.
Topics: Biological Transport; Biophysics; Cell Membrane; Cholesterol; Dithionite; Entropy; Hot Temperature; Kinetics; Lipid Bilayers; Permeability; Phosphatidylcholines; Phospholipids; Protein Transport; Thermodynamics | 2006 |
Isothermal titration calorimetric study of calcium association to lipid bilayers: influence of the vesicle preparation and composition.
Topics: Calcium; Calorimetry; Hydrogen-Ion Concentration; Lipid Bilayers; Membrane Fusion; Phosphatidylcholines; Phosphatidylglycerols; Thermodynamics; Time Factors; Titrimetry | 2006 |
Nystatin-induced lipid vesicles permeabilization is strongly dependent on sterol structure.
Topics: Cholestadienols; Cholesterol; Dehydrocholesterols; Ergosterol; Kinetics; Liposomes; Nystatin; Permeability; Phosphatidylcholines; Phytosterols; Spectrometry, Fluorescence; Sterols | 2006 |
Gradual change or phase transition: characterizing fluid lipid-cholesterol membranes on the basis of thermal volume changes.
Topics: Calorimetry; Cholesterol; Membrane Microdomains; Phase Transition; Phosphatidylcholines; Thermodynamics | 2006 |
Absence of clustering of phosphatidylinositol-(4,5)-bisphosphate in fluid phosphatidylcholine.
Topics: Cell Compartmentation; Fluorescence Resonance Energy Transfer; Hydrogen-Ion Concentration; In Vitro Techniques; Lipid Bilayers; Membrane Lipids; Membrane Microdomains; Models, Biological; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate | 2006 |
Inter-pulse interval between rectangular voltage pulses affects electroporation threshold of artificial lipid bilayers.
Topics: Dose-Response Relationship, Drug; Electroporation; Lipid Bilayers; Membrane Fluidity; Membranes, Artificial; Permeability; Phosphatidylcholines; Porosity; Radiation Dosage | 2002 |
Membrane leakage induced by dynorphins.
Topics: Amino Acid Sequence; Dynorphins; Endorphins; Fluoresceins; Liposomes; Membranes, Artificial; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids | 2006 |
Functional reconstitution of Beta2-adrenergic receptors utilizing self-assembling Nanodisc technology.
Topics: Cell Line; Chromatography, Gel; Detergents; Electrophoresis, Polyacrylamide Gel; Humans; Lipid Bilayers; Models, Biological; Nanostructures; Nanotechnology; Particle Size; Phosphatidylcholines; Protein Binding; Receptors, Adrenergic, beta-2; Recombinant Proteins; Solubility; Water | 2006 |
Determination of the lipid bilayer breakdown voltage by means of linear rising signal.
Topics: Electrons; Electroporation; Lipid Bilayers; Membrane Potentials; Phosphatidylcholines | 2007 |
Leukocytic myeloperoxidase-mediated formation of bromohydrins and lysophospholipids from unsaturated phosphatidylcholines.
Topics: Alcohols; Bromides; Catalysis; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Leukocytes; Liposomes; Lysophosphatidylcholines; Peroxidase; Phosphatidylcholines; Sodium Azide; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2006 |
31P and 2H relaxation studies of helix VII and the cytoplasmic helix of the human cannabinoid receptors utilizing solid-state NMR techniques.
Topics: Cytoplasm; Deuterium; Humans; Lipid Bilayers; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phosphorus Isotopes; Receptors, Cannabinoid | 2006 |
Hydrolysis of fluid supported membrane islands by phospholipase A(2): Time-lapse imaging and kinetic analysis.
Topics: Adsorption; Fatty Acids; Hydrolysis; Kinetics; Lysophospholipids; Membrane Lipids; Phosphatidylcholines; Phospholipases A; Phospholipids; Snake Venoms; Spectrometry, Fluorescence; Thermodynamics | 2006 |
Temperature and composition dependence of the interaction of delta-lysin with ternary mixtures of sphingomyelin/cholesterol/POPC.
Topics: Animals; Bacterial Proteins; Calorimetry, Differential Scanning; Cholesterol; Erythrocyte Membrane; Fluoresceins; Fluorescent Dyes; Hemolysin Proteins; Humans; In Vitro Techniques; Lipid Bilayers; Permeability; Phase Transition; Phosphatidylcholines; Sphingomyelins; Swine; Temperature | 2006 |
Alpha-synuclein can function as an antioxidant preventing oxidation of unsaturated lipid in vesicles.
Topics: alpha-Synuclein; Antioxidants; Boron Compounds; Circular Dichroism; Fluorescence; Kinetics; Liposomes; Oxidation-Reduction; Phosphatidylcholines; Phosphatidylglycerols | 2006 |
Indole localization in lipid membranes revealed by molecular simulation.
Topics: Benzene; Computer Simulation; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Indoles; Lipid Bilayers; Membrane Fluidity; Models, Molecular; Phosphatidylcholines; Static Electricity; Water | 2006 |
Membrane-bound dimer structure of a beta-hairpin antimicrobial peptide from rotational-echo double-resonance solid-state NMR.
Topics: Antimicrobial Cationic Peptides; Dimerization; Hydrogen Bonding; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Proteins; Phosphatidylcholines; Protein Structure, Secondary; Proteins | 2006 |
Photophysics of anthracene-indole systems in unilamellar vesicles of DMPC and POPC: Exciplex formation and temperature effects.
Topics: Anthracenes; Dimyristoylphosphatidylcholine; Indoles; Phosphatidylcholines; Photochemistry; Spectrometry, Fluorescence; Temperature; Unilamellar Liposomes | 2006 |
The structural properties of the transmembrane segment of the integral membrane protein phospholamban utilizing (13)C CPMAS, (2)H, and REDOR solid-state NMR spectroscopy.
Topics: Calcium-Binding Proteins; Lipid Bilayers; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation | 2006 |
RNA selectively interacts with vesicles depending on their size.
Topics: Cetrimonium; Cetrimonium Compounds; Escherichia coli; Nanoparticles; Particle Size; Phosphatidylcholines; RNA, Bacterial; RNA, Transfer | 2005 |
Surface tension effect on transmembrane channel stability in a model membrane.
Topics: Computer Simulation; Diffusion; Hydrogen Bonding; Lipid Bilayers; Membranes, Artificial; Models, Molecular; Phosphatidylcholines; Proteins; Solvents; Surface Tension; Thermodynamics | 2005 |
Membrane curvature change induced by an antimicrobial peptide detected by 31P exchange NMR.
Topics: Antimicrobial Cationic Peptides; Magnetic Resonance Spectroscopy; Membranes, Artificial; Phosphatidylcholines; Phosphorus Isotopes; Proteins; Sensitivity and Specificity; Time Factors | 2005 |
Different modes in antibiotic action of tritrpticin analogs, cathelicidin-derived Trp-rich and Pro/Arg-rich peptides.
Topics: Amino Acid Sequence; Antimicrobial Cationic Peptides; Carbocyanines; Cathelicidins; Cell Membrane; Drug Synergism; Escherichia coli; Membranes, Artificial; Microbial Sensitivity Tests; Oligopeptides; Phosphatidylcholines; Phosphatidylglycerols; Staphylococcus aureus | 2006 |
Interaction of protegrin-1 with lipid bilayers: membrane thinning effect.
Topics: Antimicrobial Cationic Peptides; Computer Simulation; Lipid Bilayers; Models, Molecular; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary; Proteins; Water | 2006 |
The effect of the ionophore valinomycin on biomimetic solid supported lipid DPPTE/EPC membranes.
Topics: Biomimetic Materials; Electric Impedance; Ionophores; Lipid Bilayers; Membrane Fluidity; Phosphatidylcholines; Triglycerides; Valinomycin | 2007 |
Pressure tuning of the morphology of heterogeneous lipid vesicles: a two-photon-excitation fluorescence microscopy study.
Topics: Fluorescent Dyes; Liposomes; Microscopy, Fluorescence; Phosphatidylcholines; Photons; Pressure; Thermodynamics | 2006 |
A model structure for the heterodimer apoA-IMilano-apoA-II supports its peculiar susceptibility to proteolysis.
Topics: Apolipoprotein A-I; Apolipoprotein A-II; Computer Simulation; Dimerization; Humans; Hydrolysis; Lipoproteins, HDL; Models, Molecular; Mutation; Phosphatidylcholines; Protein Structure, Secondary | 2006 |
Position of synaptotagmin I at the membrane interface: cooperative interactions of tandem C2 domains.
Topics: Animals; Cell Membrane; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Synaptotagmin I; Terbium | 2006 |
Transbilayer effects of raft-like lipid domains in asymmetric planar bilayers measured by single molecule tracking.
Topics: Cholesterol; Lipid Bilayers; Membrane Fluidity; Membrane Microdomains; Phase Transition; Phosphatidylcholines | 2006 |
Lipid headgroup superlattice modulates the activity of surface-acting cholesterol oxidase in ternary phospholipid/cholesterol bilayers.
Topics: Cholesterol; Cholesterol Oxidase; Computer Simulation; Lipid Bilayers; Models, Theoretical; Oxidation-Reduction; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids | 2006 |
Calcium-triggered membrane interaction of the alpha-synuclein acidic tail.
Topics: Adenosine; alpha-Synuclein; Amino Acid Sequence; Calcium; Cell Membrane; Circular Dichroism; Fluorescence; Glycerophospholipids; Humans; Hydrogen-Ion Concentration; Lipid Bilayers; Membrane Lipids; Molecular Sequence Data; Phosphatidylcholines; Protein Conformation; Pyrenes; Recombinant Proteins | 2006 |
Detergent-mediated phospholipidation of plasma lipoproteins increases HDL cholesterophilicity and cholesterol efflux via SR-BI.
Topics: Animals; CHO Cells; Cholesterol; Chromatography, Gel; Cricetinae; Cricetulus; Detergents; Humans; Kinetics; Lipoproteins, HDL; Lipoproteins, LDL; Models, Biological; Phosphatidylcholines; Phospholipids; Scavenger Receptors, Class B | 2006 |
A voltage-sensor water pore.
Topics: Animals; Biophysics; Cations; Computer Simulation; Ion Channel Gating; Ion Channels; Lipid Bilayers; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Potassium Channels; Potassium Channels, Voltage-Gated; Protons; Time Factors; Water | 2006 |
How phospholipid-cholesterol interactions modulate lipid lateral diffusion, as revealed by fluorescence correlation spectroscopy.
Topics: Cholesterol; Diffusion; Glycerophospholipids; Liposomes; Membrane Lipids; Microscopy, Confocal; Phosphatidylcholines; Phospholipids; Spectrometry, Fluorescence; Thermodynamics | 2006 |
Possible pathway for ubiquinone shuttling in Rhodospirillum rubrum revealed by molecular dynamics simulation.
Topics: Biological Transport; Computer Simulation; Electrons; Light-Harvesting Protein Complexes; Lipid Bilayers; Models, Chemical; Models, Molecular; Models, Statistical; Molecular Conformation; Phosphatidylcholines; Protein Conformation; Protons; Rhodospirillum rubrum; Ubiquinone | 2007 |
Ceramide drives cholesterol out of the ordered lipid bilayer phase into the crystal phase in 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine/cholesterol/ceramide ternary mixtures.
Topics: Animals; Brain Chemistry; Ceramides; Cholesterol; Cholesterol Oxidase; Crystallization; In Vitro Techniques; Kinetics; Lipid Bilayers; Phosphatidylcholines; Spectrometry, Fluorescence; Spectrophotometry | 2006 |
Leakage and lysis of lipid membranes induced by the lipopeptide surfactin.
Topics: Computer Simulation; Diffusion; Lipid Bilayers; Lipopeptides; Lipoproteins; Liposomes; Membrane Fluidity; Models, Chemical; Peptides, Cyclic; Permeability; Phosphatidylcholines; Porosity | 2007 |
Transmembrane helix packing of ErbB/Neu receptor in membrane environment: a molecular dynamics study.
Topics: Cell Membrane; Computer Simulation; Dimerization; Dimyristoylphosphatidylcholine; Lipid Bilayers; Membrane Lipids; Models, Molecular; Phosphatidylcholines; Protein Conformation; Receptor, ErbB-2 | 2006 |
Membrane-dependent oligomeric structure and pore formation of a beta-hairpin antimicrobial peptide in lipid bilayers from solid-state NMR.
Topics: Anions; Anti-Infective Agents; Antimicrobial Cationic Peptides; Cholesterol; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Proteins | 2006 |
SGTx1, a Kv channel gating-modifier toxin, binds to the interfacial region of lipid bilayers.
Topics: Animals; Cell Membrane; Lipid Bilayers; Lipids; Models, Molecular; Phosphatidylcholines; Phosphatidylglycerols; Potassium Channels, Voltage-Gated; Protein Conformation; Spider Venoms; Static Electricity; Time Factors; Water | 2007 |
Cholesterol surrogates: a comparison of cholesterol and 16:0 ceramide in POPC bilayers.
Topics: Ceramides; Cholesterol; Computer Simulation; Lipid Bilayers; Membrane Fluidity; Models, Chemical; Models, Molecular; Phosphatidylcholines; Stress, Mechanical | 2007 |
Water near lipid membranes as seen by infrared spectroscopy.
Topics: Humidity; Hydrogen Bonding; Lipid Bilayers; Phosphatidylcholines; Solutions; Spectrophotometry, Infrared; Temperature; Unilamellar Liposomes; Water | 2007 |
Insight into the putative specific interactions between cholesterol, sphingomyelin, and palmitoyl-oleoyl phosphatidylcholine.
Topics: Cholesterol; Computer Simulation; Dimerization; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Membrane Fluidity; Models, Molecular; Molecular Conformation; Phase Transition; Phosphatidylcholines; Sphingomyelins | 2007 |
The cooperative response of synaptotagmin I C2A. A hypothesis for a Ca2+-driven molecular hammer.
Topics: Calcium; Exocytosis; Membranes, Artificial; Models, Biological; Phosphatidylcholines; Phosphatidylserines; Protein Structure, Tertiary; Recombinant Proteins; Synaptic Vesicles; Synaptotagmin I | 2007 |
Atomic-scale structure and electrostatics of anionic palmitoyloleoylphosphatidylglycerol lipid bilayers with Na+ counterions.
Topics: Anions; Cations, Divalent; Computer Simulation; Hydrogen Bonding; Lipid Bilayers; Models, Molecular; Molecular Structure; Phosphatidylcholines; Phosphatidylglycerols; Sodium; Static Electricity; Water | 2007 |
Newly developed reconstituted high-density lipoprotein containing sphingosine-1-phosphate induces endothelial tube formation.
Topics: Animals; Atherosclerosis; Cell Division; Cells, Cultured; CHO Cells; Cholesterol; Coronary Vessels; Cricetinae; Cricetulus; Endothelial Cells; Enzyme Inhibitors; Humans; In Vitro Techniques; Lipoproteins, HDL; Lysophospholipids; Macrophages; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oligonucleotides, Antisense; Phosphatidylcholines; Proto-Oncogene Proteins c-akt; ras Proteins; Sphingosine | 2007 |
Reactions of hydrogen atoms with met-enkephalin and related peptides.
Topics: Enkephalin, Leucine; Enkephalin, Methionine; Hydrogen; Peptides; Phosphatidylcholines | 2007 |
Ionic conductivity of the aqueous layer separating a lipid bilayer membrane and a glass support.
Topics: Electric Conductivity; Glass; Lipid Bilayers; Membranes, Artificial; Phosphatidylcholines; Potassium; Surface Properties; Water | 2006 |
Characterization of physical properties of supported phospholipid membranes using imaging ellipsometry at optical wavelengths.
Topics: Cholera Toxin; Dimyristoylphosphatidylcholine; G(M1) Ganglioside; Galactosylceramides; Lipid Bilayers; Microscopy; Phase Transition; Phosphatidylcholines | 2007 |
Ergosterol in POPC membranes: physical properties and comparison with structurally similar sterols.
Topics: Deuterium; Ergosterol; Lipid Bilayers; Nuclear Magnetic Resonance, Biomolecular; Phase Transition; Phosphatidylcholines; Thermodynamics | 2007 |
Functional reconstitution of the integral membrane enzyme, isoprenylcysteine carboxyl methyltransferase, in synthetic bolalipid membrane vesicles.
Topics: Cell Membrane; Diffusion; Kinetics; Membrane Lipids; Models, Molecular; Phosphatidylcholines; Protein Conformation; Protein Methyltransferases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thermodynamics | 2006 |
Effects of an amphipathic alpha-helical peptide on lateral pressure and water penetration in phosphatidylcholine and monoolein mixed membranes.
Topics: Fluorescence; Glycerides; Membranes, Artificial; Peptides; Phase Transition; Phosphatidylcholines; Pressure; Protein Structure, Secondary; Pyrenes; Stearic Acids; Surface-Active Agents; Water | 2006 |
A versatile method for determining the molar ligand-membrane partition coefficient.
Topics: Antipsychotic Agents; Chlorpromazine; Fluorescence; Fluorescent Dyes; Ligands; Liposomes; Membrane Lipids; Molecular Structure; Phosphatidylcholines; Phosphatidylserines; Spectrometry, Fluorescence; Water | 2007 |
The melting of pulmonary surfactant monolayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Biological Products; Biomechanical Phenomena; Cattle; Elasticity; Hydrostatic Pressure; Microbubbles; Models, Biological; Molecular Conformation; Phase Transition; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; Respiratory Mechanics; Surface Properties; Time Factors; Transition Temperature | 2007 |
Spontaneous, intervesicular transfer rates of fluorescent, acyl chain-labeled phosphatidylcholine analogs.
Topics: Azoles; Fluorescent Dyes; Fluorometry; Kinetics; Molecular Structure; Nitrobenzenes; Phosphatidylcholines | 2007 |
Investigation of domain formation in sphingomyelin/cholesterol/POPC mixtures by fluorescence resonance energy transfer and Monte Carlo simulations.
Topics: Cholesterol; Complex Mixtures; Computer Simulation; Fluorescence Resonance Energy Transfer; Membrane Fluidity; Membrane Microdomains; Models, Chemical; Models, Molecular; Models, Statistical; Monte Carlo Method; Phase Transition; Phosphatidylcholines; Sphingomyelins | 2007 |
Optimising histidine rich peptides for efficient DNA delivery in the presence of serum.
Topics: Cell Line, Transformed; Cell Line, Tumor; Cell Transformation, Viral; Cells, Cultured; Cholesterol; DNA; Drug Carriers; Flow Cytometry; Histidine; Humans; Lipids; Luciferases; Models, Chemical; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphatidylcholines; Phosphatidylserines; Serum; Transfection | 2007 |
Ganglioside G(M1)-mediated amyloid-beta fibrillogenesis and membrane disruption.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Amyloid; Amyloid beta-Peptides; G(M1) Ganglioside; Lipid Bilayers; Membranes, Artificial; Microscopy, Fluorescence; Phosphatidylcholines | 2007 |
Shiga toxin B-subunit sequential binding to its natural receptor in lipid membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Amino Acid Sequence; Binding Sites; Buffers; Circular Dichroism; Escherichia coli; Globosides; Models, Chemical; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Conformation; Recombinant Proteins; Shiga Toxin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Trihexosylceramides; Tryptophan; Unilamellar Liposomes; Water | 2007 |
Kinetic models for peptide-induced leakage from vesicles and cells.
Topics: Animals; Cattle; Cell Membrane Permeability; Kinetics; Liposomes; Membranes; Mice; Models, Biological; Peptides; Permeability; Phosphatidylcholines; Phosphatidylglycerols; Prion Proteins; Prions | 2007 |
Fluorescence spectroscopic studies of pressure effects on Na+,K(+)-ATPase reconstituted into phospholipid bilayers and model raft mixtures.
Topics: 2-Naphthylamine; Animals; Cell Membrane; Cholesterol; Enzyme Activation; Fluorescent Dyes; Kidney; Laurates; Lipid Bilayers; Membrane Microdomains; Phosphatidylcholines; Pressure; Rabbits; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence; Sphingomyelins; Swine | 2007 |
Impact of aluminum on the oxidation of lipids and enzymatic lipolysis in monomolecular films at the air/water interface.
Topics: Air; Aluminum; Animals; Calcium; Candida; Enzymes; Lipase; Lipids; Oxygen; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Surface Properties; Swine; Triglycerides; Water | 2007 |
Dynamic recompartmentalization of supported lipid bilayers using focused femtosecond laser pulses.
Topics: Biomimetic Materials; Cell Membrane; Cell Membrane Permeability; Lasers; Lipid Bilayers; Microscopy, Fluorescence; Phosphatidylcholines | 2007 |
Deprotonation by dehydration: the origin of ammonium sensing in the AmtB channel.
Topics: Cation Transport Proteins; Computer Simulation; Escherichia coli Proteins; Ion Channel Gating; Lipid Bilayers; Models, Chemical; Models, Molecular; Phosphatidylcholines; Protons; Quaternary Ammonium Compounds; Water | 2007 |
Fabrication of biofunctional nanomaterials via Escherichia coli OmpF protein air/water interface insertion/integration with copolymeric amphiphiles.
Topics: Air; Escherichia coli; Models, Molecular; Nanostructures; Phase Transition; Phosphatidylcholines; Polymers; Porins; Protein Structure, Tertiary; Surface-Active Agents; Water | 2006 |
Interaction of the C2 domain from protein kinase C(epsilon) with model membranes.
Topics: Animals; Calorimetry, Differential Scanning; Membranes, Artificial; Nuclear Magnetic Resonance, Biomolecular; Phosphatidic Acids; Phosphatidylcholines; Phosphorus Isotopes; Protein Kinase C-epsilon; Protein Structure, Tertiary; Protein Transport; Rats; Spectrophotometry, Infrared; Static Electricity | 2007 |
The use of solvent relaxation technique to investigate headgroup hydration and protein binding of simple and mixed phosphatidylcholine/surfactant bilayer membranes.
Topics: 2-Naphthylamine; Animals; Chemistry Techniques, Analytical; Fluorescent Dyes; Laurates; Lipid Bilayers; Melitten; Palmitic Acids; Phosphatidylcholines; Plant Oils; Polyethylene Glycols; Polysorbates; Protein Binding; Solvents; Spectrometry, Fluorescence; Surface-Active Agents; Time Factors; Water | 2007 |
How does pulmonary surfactant reduce surface tension to very low values?
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Biomechanical Phenomena; Humans; Liposomes; Microbubbles; Models, Biological; Molecular Conformation; Phase Transition; Phosphatidylcholines; Pressure; Pulmonary Alveoli; Pulmonary Surfactants; Respiratory Mechanics; Surface Properties; Transition Temperature | 2007 |
Molecular dynamics study of small PNA molecules in lipid-water system.
Topics: Computer Simulation; Kinetics; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Peptide Nucleic Acids; Phosphatidylcholines; Water | 2007 |
Effects of reconstituted HDL on charge-based LDL subfractions as characterized by capillary isotachophoresis.
Topics: Apolipoprotein A-I; Cholesterol, HDL; Cholesterol, LDL; Electrophoresis, Capillary; Humans; Microscopy, Electron; Phosphatidylcholines | 2007 |
Solid state NMR investigation of the interaction between biomimetic lipid bilayers and de novo designed fusogenic peptides.
Topics: Amino Acid Sequence; Biochemistry; Biomimetics; Lipid Bilayers; Lipids; Magnetic Resonance Spectroscopy; Membrane Fluidity; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Protons | 2007 |
Hydration of POPC bilayers studied by 1H-PFG-MAS-NOESY and neutron diffraction.
Topics: Absorption; Hydrogen Bonding; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Neutron Diffraction; Phosphatidylcholines; Protons; Solutions; Water | 2007 |
Distribution of reaction products in phospholipase A2 hydrolysis.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Catalysis; Elapid Venoms; Hydrolysis; Kinetics; Lipid Bilayers; Models, Biological; Neutron Diffraction; Pancreas; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Protein Binding; Swine | 2007 |
Influence of cholesterol and ergosterol on membrane dynamics using different fluorescent reporter probes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Diphenylhexatriene; Ergosterol; Fluorescence Polarization; Fluorescent Dyes; Membranes, Artificial; Phosphatidylcholines; Pyrenes | 2007 |
Atomic force microscopy and force spectroscopy study of Langmuir-Blodgett films formed by heteroacid phospholipids of biological interest.
Topics: Air; Microscopy, Atomic Force; Phosphatidylcholines; Phosphatidylethanolamines; Spectrum Analysis; Surface Properties; Water | 2007 |
Dynamics of alpha-synuclein aggregation and inhibition of pore-like oligomer development by beta-synuclein.
Topics: alpha-Synuclein; beta-Synuclein; Cations; Cell Line; Computer Simulation; Electrophysiology; Humans; Ion Channels; Microscopy, Electron, Scanning; Models, Molecular; Phosphatidylcholines; Protein Binding; Protein Conformation; Protein Structure, Quaternary; Protein Structure, Secondary; Static Electricity; Transfection; Zinc | 2007 |
Omiganan interaction with bacterial membranes and cell wall models. Assigning a biological role to saturation.
Topics: Antimicrobial Cationic Peptides; Cell Membrane; Cell Wall; Cholesterol; Kinetics; Models, Biological; Peptides; Peptidoglycan; Phosphatidylcholines; Spectrometry, Fluorescence; Staphylococcus aureus | 2007 |
Novel liposomal formulation for targeted gene delivery.
Topics: Animals; Antibodies, Monoclonal; Cell Line, Tumor; Cholesterol; DNA; Drug Compounding; Gene Targeting; Genetic Vectors; Half-Life; Hydrogen-Ion Concentration; Kinetics; Liposomes; Mice; Microscopy, Electron, Transmission; Particle Size; Phosphatidylcholines; Polyethylene Glycols; Receptors, Transferrin; Temperature; Time Factors; Transfection | 2007 |
Acetyl-[Asn30,Tyr32]-calcitonin fragment 8-32 forms channels in phospholipid planar lipid membranes.
Topics: Animals; Calcitonin; Ion Channel Gating; Ion Channels; Membranes, Artificial; Peptides; Phosphatidylcholines; Phosphatidylglycerols | 2007 |
Determining the orientation of uniaxially rotating membrane proteins using unoriented samples: a 2H, 13C, AND 15N solid-state NMR investigation of the dynamics and orientation of a transmembrane helical bundle.
Topics: Algorithms; Anisotropy; Cytoplasm; Electromagnetic Fields; Lipid Bilayers; Lipids; Magnetic Resonance Spectroscopy; Membrane Proteins; Membranes, Artificial; Models, Molecular; Peptides; Phosphatidylcholines; Temperature | 2007 |
Lipid transmembrane asymmetry and intrinsic membrane potential: two sides of the same coin.
Topics: Electrochemistry; Hydrogen Bonding; Lipid Bilayers; Membrane Potentials; Membranes, Artificial; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids | 2007 |
Specific adsorption of cytochrome C on cardiolipin-glycerophospholipid monolayers and bilayers.
Topics: Adsorption; Cardiolipins; Cytochromes c; Lipid Bilayers; Liposomes; Microscopy, Atomic Force; Phosphatidylcholines; Phosphatidylethanolamines; Pressure | 2007 |
Performance of the general amber force field in modeling aqueous POPC membrane bilayers.
Topics: Electrons; Lipid Bilayers; Membrane Lipids; Models, Molecular; Molecular Structure; Phosphatidylcholines; Water | 2007 |
The insertion of the antimicrobial peptide dicynthaurin monomer in model membranes: thermodynamics and structural characterization.
Topics: Calorimetry; Circular Dichroism; Membrane Lipids; Membranes, Artificial; Models, Molecular; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Thermodynamics | 2007 |
DHA-induced changes of supported lipid membrane morphology.
Topics: Biosensing Techniques; Docosahexaenoic Acids; In Vitro Techniques; Lipid Bilayers; Membrane Lipids; Microscopy, Fluorescence; Phosphatidylcholines; Quartz; Surface Properties | 2007 |
Sensor of phospholipids in Streptomyces phospholipase D.
Topics: Amino Acid Sequence; Liposomes; Phosphatidylcholines; Phospholipase D; Phospholipids; Protein Conformation; Spectrometry, Fluorescence; Streptomyces; Surface Plasmon Resonance | 2007 |
A novel strategy for bioconjugation: synthesis and preliminary evaluation with amphotericin B.
Topics: Amides; Amination; Amphotericin B; Antifungal Agents; Biotin; Liposomes; Phosphatidylcholines; Potassium; Potentiometry | 2007 |
Concentration dependence of a poly-leucine surfactant protein C analogue on in vitro and in vivo surfactant activity.
Topics: Animals; Animals, Newborn; Dose-Response Relationship, Drug; Forced Expiratory Flow Rates; In Vitro Techniques; Lung; Phosphatidylcholines; Phosphatidylglycerols; Pulmonary Alveoli; Pulmonary Surfactant-Associated Protein C; Rabbits; Respiration, Artificial; Surface Tension; Tidal Volume | 2007 |
Characterization of lipid bilayer formation in aligned nanoporous aluminum oxide nanotube arrays.
Topics: Aluminum Oxide; Buffers; Deuterium; Lipid Bilayers; Lipids; Nanotubes; Phosphatidylcholines; Phospholipids; Phosphorus Isotopes; Porosity; Proteins | 2007 |
New antitumoral acetogenin 'Guanacone type' derivatives: isolation and bioactivity. Molecular dynamics simulation of diacetyl-guanacone.
Topics: Acetogenins; Annona; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Computer Simulation; Electron Transport; Fatty Alcohols; Furans; Humans; Hydrogen Bonding; Indicators and Reagents; Lactones; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Seeds | 2007 |
Formation of ceramide/sphingomyelin gel domains in the presence of an unsaturated phospholipid: a quantitative multiprobe approach.
Topics: Anisotropy; Biophysics; Ceramides; Gels; Lipids; Membrane Fluidity; Membrane Lipids; Models, Statistical; Palmitic Acids; Phosphatidylcholines; Phospholipids; Protein Structure, Tertiary; Spectrometry, Fluorescence; Sphingomyelins | 2007 |
Comparison of the interaction of dihydrocholesterol and cholesterol with sphingolipid or phospholipid Langmuir monolayers.
Topics: Biophysical Phenomena; Biophysics; Cholestanol; Cholesterol; Membranes, Artificial; Phosphatidylcholines; Phospholipids; Sphingolipids; Sphingomyelins; Surface Properties | 2007 |
POPC/apoA-I discs as a potent lipoprotein modulator in Tangier disease.
Topics: Apolipoprotein A-I; Apolipoproteins B; Apolipoproteins E; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cells, Cultured; Cholesterol Esters; Cholesterol, HDL; Electrophoresis; Humans; Macrophages; Phosphatidylcholines; Tangier Disease; Triglycerides | 2008 |
Conformational adaptation of apolipoprotein A-I to discretely sized phospholipid complexes.
Topics: Apolipoprotein A-I; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Humans; Lipoproteins, HDL; Models, Molecular; Phosphatidylcholines; Phospholipids; Protein Conformation; Recombinant Proteins; Succinimides; Tandem Mass Spectrometry | 2007 |
Development of non-phospholipid liposomes containing a high cholesterol concentration.
Topics: Cholesterol; Hydrogen-Ion Concentration; Lipid Bilayers; Liposomes; Palmitic Acid; Permeability; Phosphatidylcholines; Phospholipids; Time Factors | 2007 |
Structural effects in the analysis of supported lipid bilayers by time-of-flight secondary ion mass spectrometry.
Topics: Lipid Bilayers; Phosphatidylcholines; Spectrometry, Mass, Secondary Ion | 2007 |
Infrared spectroscopy study on the conformational changes leading to pore formation of the toxin sticholysin II.
Topics: Animals; Cholesterol; Cnidarian Venoms; Membranes, Artificial; Phosphatidylcholines; Pore Forming Cytotoxic Proteins; Protein Conformation; Protein Structure, Secondary; Sea Anemones; Spectrophotometry, Infrared; Toxins, Biological | 2007 |
Is lipid bilayer binding a common property of inhibitor cysteine knot ion-channel blockers?
Topics: Amino Acid Sequence; Fluorescence; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Intercellular Signaling Peptides and Proteins; Ion Channels; Lipid Bilayers; Membrane Potentials; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Spider Venoms; Static Electricity; Stereoisomerism; Thermodynamics | 2007 |
Tetrahydro-1,8-naphthyridinol analogues of alpha-tocopherol as antioxidants in lipid membranes and low-density lipoproteins.
Topics: alpha-Tocopherol; Antioxidants; Carrier Proteins; Humans; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Liposomes; Models, Molecular; Naphthyridines; Phosphatidylcholines | 2007 |
Mechanism of islet amyloid polypeptide fibrillation at lipid interfaces studied by infrared reflection absorption spectroscopy.
Topics: Adsorption; Amyloid; Animals; Humans; Islet Amyloid Polypeptide; Phosphatidylcholines; Phosphatidylglycerols; Rats; Spectrophotometry, Infrared; Static Electricity; Water | 2007 |
Investigating the interaction of saposin C with POPS and POPC phospholipids: a solid-state NMR spectroscopic study.
Topics: Amino Acid Sequence; Carbon; Catalysis; Escherichia coli; Hydrogen-Ion Concentration; Hydrolysis; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Protein Binding; Saposins; Temperature | 2007 |
Interaction of an amphipathic peptide with phosphatidycholine/phosphatidylethanolamine mixed membranes.
Topics: Binding Sites; Complex Mixtures; Lipid Bilayers; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Protein Binding; Surface-Active Agents | 2007 |
Molecular dynamics studies of the molecular structure and interactions of cholesterol superlattices and random domains in an unsaturated phosphatidylcholine bilayer membrane.
Topics: Cholesterol; Deuterium; Hydrogen Bonding; Lipid Bilayers; Membranes, Artificial; Molecular Structure; Nanostructures; Phosphatidylcholines | 2007 |
Conformation, dynamics, and insertion of a noncysteine-containing protegrin-1 analogue in lipid membranes from solid-state NMR spectroscopy.
Topics: Alanine; Amino Acid Sequence; Anti-Infective Agents; Antimicrobial Cationic Peptides; Carbon Radioisotopes; Cell Membrane; Cholesterol; Cysteine; Disulfides; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Protein Conformation; Proteins | 2007 |
The influence of headgroup structure and fatty acyl chain saturation of phospholipids on monolayer behavior: a comparative rheological study.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Biochemistry; Chloroform; Fatty Acids; Membrane Lipids; Models, Chemical; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rheology; Surface Properties | 2007 |
In situ investigation of heterotrimeric G protein betagamma subunit binding and orientation on membrane bilayers.
Topics: Adsorption; Amides; Biochemistry; Cryoelectron Microscopy; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Lipid Bilayers; Lipids; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Poisson Distribution; Protein Binding; Signal Transduction; Spectrophotometry | 2007 |
The structural topology of wild-type phospholamban in oriented lipid bilayers using 15N solid-state NMR spectroscopy.
Topics: Calcium-Binding Proteins; Cytoplasm; Humans; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Nitrogen Isotopes; Phosphatidylcholines; Phospholipids; Protein Conformation; Protein Structure, Tertiary | 2007 |
Side chain and backbone dynamics of phospholamban in phospholipid bilayers utilizing 2H and 15N solid-state NMR spectroscopy.
Topics: Calcium-Binding Proteins; Deuterium; Lipid Bilayers; Models, Chemical; Molecular Structure; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phospholipids; Phosphorylation; Protein Binding; Protein Structure, Secondary; Temperature | 2007 |
Phase studies of model biomembranes: macroscopic coexistence of Lalpha+Lbeta, with light-induced coexistence of Lalpha+Lo Phases.
Topics: Cholesterol; Light; Lipid Bilayers; Membrane Microdomains; Phase Transition; Phosphatidylcholines; Propyl Gallate; Sphingomyelins; Temperature | 2007 |
Effects of lipid phase transition and membrane surface charge on the interfacial activation of phospholipase A2.
Topics: Dimyristoylphosphatidylcholine; Enzyme Activation; Humans; Membrane Lipids; Phase Transition; Phosphatidylcholines; Phosphatidylglycerols; Phospholipases A2; Temperature; Unilamellar Liposomes | 2007 |
Apolipoprotein A-IMilano/POPC complex attenuates post-ischemic ventricular dysfunction in the isolated rabbit heart.
Topics: Animals; Antioxidants; Apolipoprotein A-I; Disease Models, Animal; Lipid Peroxidation; Lipoproteins, HDL; Male; Microscopy, Electron; Myocardial Reperfusion Injury; Phosphatidylcholines; Rabbits; Recombinant Proteins; Ventricular Dysfunction | 2008 |
An improved NMR study of liposomes using 1-palmitoyl-2-oleoyl-sn-glycero-3-phospatidylcholine as model.
Topics: Light; Liposomes; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Phosphatidylcholines; Scattering, Radiation | 2006 |
Membrane binding of pH-sensitive influenza fusion peptides. positioning, configuration, and induced leakage in a lipid vesicle model.
Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Hemagglutinin Glycoproteins, Influenza Virus; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Membrane Fusion; Models, Biological; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Peptides; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Tryptophan; Unilamellar Liposomes | 2007 |
Interactions of fusidic acid and elongation factor G with lipid membranes.
Topics: Capillary Electrochromatography; Cholesterol; Electroosmosis; Fusidic Acid; Liposomes; Membranes, Artificial; Peptide Elongation Factor G; Phosphatidylcholines | 2008 |
Macromolecular crowding at membrane interfaces: adsorption and alignment of membrane peptides.
Topics: Adsorption; Bacterial Proteins; Buffers; Circular Dichroism; Computer Simulation; DNA-Binding Proteins; Hydrogen-Ion Concentration; Membrane Proteins; Models, Chemical; Osmolar Concentration; Peptides; Phosphates; Phosphatidylcholines; Potassium Chloride; Protein Binding; Protein Conformation; Protein Structure, Secondary; Solutions; Spectrometry, Fluorescence; Surface Properties; Unilamellar Liposomes; Water | 2008 |
Antimicrobial effectiveness of liposomal polymyxin B against resistant Gram-negative bacterial strains.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Anti-Bacterial Agents; Biological Assay; Chemistry, Pharmaceutical; Cholesterol; Drug Carriers; Drug Compounding; Drug Resistance, Bacterial; Gram-Negative Bacteria; Immunohistochemistry; Liposomes; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Phosphatidylcholines; Polymyxin B; Pseudomonas aeruginosa; Rats | 2008 |
Characterization of the ternary mixture of sphingomyelin, POPC, and cholesterol: support for an inhomogeneous lipid distribution at high temperatures.
Topics: Cholesterol; Complex Mixtures; Membrane Fluidity; Membrane Lipids; Membrane Microdomains; Molecular Conformation; Phase Transition; Phosphatidylcholines; Sphingomyelins; Temperature | 2008 |
Formation of a high affinity lipid-binding intermediate during the early aggregation phase of alpha-synuclein.
Topics: alpha-Synuclein; Circular Dichroism; Humans; Lipids; Microscopy, Electron; Phosphatidylcholines; Phosphatidylserines; Protein Structure, Quaternary; Protein Structure, Secondary; Surface Plasmon Resonance; Unilamellar Liposomes | 2008 |
Lipid diffusion from single molecules of a labeled protein undergoing dynamic association with giant unilamellar vesicles and supported bilayers.
Topics: Animals; Diazepam Binding Inhibitor; Diffusion; Fluorescent Dyes; Lipid Bilayers; Mice; Phosphatidylcholines; Proteins; Recombinant Proteins; Thermodynamics | 2008 |
Cationic amphiphiles and the solubilization of cholesterol crystallites in membrane bilayers.
Topics: Calorimetry, Differential Scanning; Cholesterol; Electron Spin Resonance Spectroscopy; Fatty Acids, Monounsaturated; Lipid Bilayers; Phosphatidylcholines; Phosphatidylserines; Quaternary Ammonium Compounds; Solubility; Temperature; Thermodynamics | 2008 |
pH-sensitive vesicles containing a lipidic beta-amino acid with two hydrophobic chains.
Topics: Alkylation; Amino Acids; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Lipids; Molecular Structure; Phosphatidylcholines; Phosphatidylglycerols; Sensitivity and Specificity | 2008 |
N-palmitoyl-sulfatide participates in lateral domain formation in complex lipid bilayers.
Topics: Animals; Calcium; Chickens; Fatty Acids, Unsaturated; Galactosylceramides; Lipid Bilayers; Phosphatidylcholines; Sphingomyelins; Sterols; Sulfoglycosphingolipids; Temperature | 2008 |
Characterization of phosphatidylcholine/polyethylene glycol-lipid aggregates and their use as coatings and carriers in capillary electrophoresis.
Topics: Amino Acids; Cryoelectron Microscopy; Electrophoresis, Capillary; Liposomes; Micelles; Microscopy, Atomic Force; Phosphatidylcholines; Polyethylene Glycols | 2008 |
Lipid-protein nanoscale bilayers: a versatile medium for NMR investigations of membrane proteins and membrane-active peptides.
Topics: Amino Acid Sequence; Apolipoprotein A-I; Lipid Bilayers; Membrane Proteins; Molecular Sequence Data; Nanostructures; Nuclear Magnetic Resonance, Biomolecular; Peptaibols; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids | 2008 |
Glycosylation induces shifts in the lateral distribution of cholesterol from ordered towards less ordered domains.
Topics: Anisotropy; Calorimetry, Differential Scanning; Cholesterol; Glucosides; Glycosylation; Lipid Bilayers; Membrane Fluidity; Phosphatidylcholines; Pressure | 2008 |
Electroformation in a flow chamber with solution exchange as a means of preparation of flaccid giant vesicles.
Topics: Electric Conductivity; Electrochemistry; Glycerol; Permeability; Pharmaceutical Solutions; Phosphatidylcholines; Phospholipids; Unilamellar Liposomes | 2008 |
Rapid incorporation of functional rhodopsin into nanoscale apolipoprotein bound bilayer (NABB) particles.
Topics: Amino Acid Sequence; Animals; Apolipoprotein A-I; Biomimetics; Cattle; Fluorescent Dyes; Humans; Lipid Bilayers; Molecular Sequence Data; Nanoparticles; Phosphatidylcholines; Receptors, G-Protein-Coupled; Rho Factor; Rhodopsin; Sequence Homology, Amino Acid; Zebrafish | 2008 |
Study of the interaction of beta-cyclodextrin with phospholipid monolayers by surface pressure measurements and fluorescence microscopy.
Topics: Adsorption; beta-Cyclodextrins; Fluorescent Dyes; Lipid Bilayers; Microscopy, Fluorescence; Phosphatidylcholines; Phospholipids; Stress, Mechanical; Surface Properties; Surface-Active Agents; Temperature; Time Factors | 2008 |
Sifuvirtide screens rigid membrane surfaces. establishment of a correlation between efficacy and membrane domain selectivity among HIV fusion inhibitor peptides.
Topics: Acrylamide; Amino Acid Sequence; Enfuvirtide; Fluorescence Resonance Energy Transfer; HIV Envelope Protein gp41; HIV Fusion Inhibitors; Lipid Bilayers; Membrane Fluidity; Membrane Lipids; Molecular Sequence Data; Peptide Fragments; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Solutions; Water | 2008 |
Modeling membranes under a transmembrane potential.
Topics: Computer Simulation; Lipid Bilayers; Membrane Potentials; Models, Biological; Nanotubes, Peptide; Phosphatidylcholines; Static Electricity | 2008 |
Letter: collision-induced dissociation of [metal(L)(2)](2+) complexes (metal = Cu, Ca and Mg) of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine allows distinction of the acyl groups at the sn1 and sn2 positions.
Topics: Calcium; Copper; Magnesium; Phosphatidylcholines; Spectrometry, Mass, Electrospray Ionization | 2007 |
Broken helix in vesicle and micelle-bound alpha-synuclein: insights from site-directed spin labeling-EPR experiments and MD simulations.
Topics: alpha-Synuclein; Amino Acid Sequence; Computer Simulation; Electron Spin Resonance Spectroscopy; Humans; Lipid Bilayers; Micelles; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Protein Structure, Secondary; Sodium Dodecyl Sulfate; Spin Labels | 2008 |
Surface plasmon resonance study of vesicle rupture by virus-mimetic attack.
Topics: Biomimetics; Chemistry, Physical; Crystallization; Equipment Design; Gold; Hepacivirus; Lipid Bilayers; Lipids; Peptides; Phosphatidylcholines; Quartz; Surface Plasmon Resonance; Time Factors; Viruses | 2008 |
Partitioning of 1-pyrenesulfonate into zwitterionic and mixed zwitterionic/anionic fluid phospholipid bilayers.
Topics: Lipid Bilayers; Liposomes; Osmolar Concentration; Phosphatidylcholines; Phosphatidylserines; Pyrenes; Spectrophotometry, Ultraviolet; Sulfonic Acids | 2008 |
Cholesterol packing around lipids with saturated and unsaturated chains: a simulation study.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Computer Simulation; Lipid Bilayers; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Water | 2008 |
Prediction of binding free energy for adsorption of antimicrobial peptide lactoferricin B on a POPC membrane.
Topics: Adsorption; Algorithms; Animals; Antimicrobial Cationic Peptides; Biophysics; Cattle; Computer Simulation; Lactoferrin; Models, Statistical; Molecular Conformation; Peptides; Phosphatidylcholines; Protein Binding; Stress, Mechanical; Thermodynamics | 2008 |
Insight into the mechanism of inactivation and pH sensitivity in potassium channels from molecular dynamics simulations.
Topics: Amino Acid Sequence; Computer Simulation; Humans; Hydrogen-Ion Concentration; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Potassium Channels; Protein Conformation | 2008 |
Activation mechanism of the human histamine H4 receptor--an explicit membrane molecular dynamics simulation study.
Topics: Binding Sites; Cell Membrane; Computer Simulation; Conserved Sequence; Drug Design; Extracellular Space; Histamine; Humans; Indoles; Intracellular Space; Ligands; Models, Molecular; Movement; Phosphatidylcholines; Piperazines; Protein Structure, Secondary; Protons; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Water | 2008 |
Membrane domain formation, interdigitation, and morphological alterations induced by the very long chain asymmetric C24:1 ceramide.
Topics: Calorimetry, Differential Scanning; Cell Membrane; Ceramides; Microscopy, Confocal; Phosphatidylcholines; Solubility; Spectrometry, Fluorescence; Unilamellar Liposomes; X-Ray Diffraction | 2008 |
Mechanosensitive channel MscS in the open state: modeling of the transition, explicit simulations, and experimental measurements of conductance.
Topics: Chlorine; Computer Simulation; Diffusion; Electric Conductivity; Electrophysiology; Escherichia coli Proteins; Ion Channel Gating; Ion Channels; Ions; Lipid Bilayers; Membrane Potentials; Models, Molecular; Phosphatidylcholines; Potassium; Protein Conformation; Static Electricity; Water | 2008 |
Parallel-oriented fibrogenesis of a beta-sheet forming peptide on supported lipid bilayers.
Topics: Amyloid beta-Peptides; Circular Dichroism; Lipid Bilayers; Microscopy, Atomic Force; Phosphatidylcholines; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared | 2008 |
Complex formation of amphotericin B in sterol-containing membranes as evidenced by surface plasmon resonance.
Topics: Amphotericin B; Cholesterol; Ergosterol; Liposomes; Models, Biological; Molecular Structure; Phosphatidylcholines; Sterols; Surface Plasmon Resonance | 2008 |
Softening of POPC membranes by magainin.
Topics: Magainins; Membranes; Membranes, Artificial; Peptides; Phosphatidylcholines | 2008 |
Biomolecular engineering by combinatorial design and high-throughput screening: small, soluble peptides that permeabilize membranes.
Topics: Amino Acid Sequence; Cell Membrane Permeability; Combinatorial Chemistry Techniques; Lipid Bilayers; Liposomes; Molecular Sequence Data; Peptide Library; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Engineering; Protein Structure, Secondary; Solubility; Spectrometry, Fluorescence; Structure-Activity Relationship | 2008 |
Directed aggregation and fusion of lipid vesicles induced by DNA-surfactants.
Topics: DNA; DNA Restriction Enzymes; Lipid Bilayers; Liposomes; Membrane Fusion; Phosphatidylcholines; Sodium Chloride; Surface-Active Agents; Temperature | 2008 |
The helical structure of surfactant peptide KL4 when bound to POPC: POPG lipid vesicles.
Topics: Amino Acid Sequence; Binding Sites; Intercellular Signaling Peptides and Proteins; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary; Pulmonary Surfactants | 2008 |
Cholesterol interactions with fluid-phase phospholipids: effect on the lateral organization of the bilayer.
Topics: Anisotropy; beta-Cyclodextrins; Cholesterol; Diphenylhexatriene; Fluorescence; Lipid Bilayers; Membrane Fluidity; Phase Transition; Phosphatidylcholines; Phospholipids; Sphingomyelins | 2008 |
Probing mechanical properties of liposomes using acoustic sensors.
Topics: Acoustics; Chemistry Techniques, Analytical; Cholesterol; Liposomes; Phosphatidylcholines | 2008 |
Cellular uptake and membrane-destabilising properties of alpha-peptide/beta-peptoid chimeras: lessons for the design of new cell-penetrating peptides.
Topics: Animals; Cell Membrane; Cell Membrane Permeability; Cytoplasmic Vesicles; Flow Cytometry; Fluoresceins; Gene Products, tat; Guanidine; HeLa Cells; Humans; Membranes, Artificial; Mice; Microscopy, Confocal; NIH 3T3 Cells; Peptides; Peptoids; Phase Transition; Phosphatidylcholines; Phosphatidylglycerols; Temperature | 2008 |
A steroid in a lipid bilayer: localization, orientation, and energetics.
Topics: Cortisone; Lipid Bilayers; Models, Molecular; Phosphatidylcholines; Thermodynamics | 2008 |
High vapor pressure perfluorocarbons cause vesicle fusion and changes in membrane packing.
Topics: Fluorocarbons; Membrane Fluidity; Membrane Fusion; Membranes, Artificial; Phosphatidylcholines; Unilamellar Liposomes; Vapor Pressure | 2008 |
Pore structure, thinning effect, and lateral diffusive dynamics of oriented lipid membranes interacting with antimicrobial peptide protegrin-1: 31P and 2H solid-state NMR study.
Topics: Antimicrobial Cationic Peptides; Deuterium; Diffusion; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphorus Isotopes; Porosity | 2008 |
Molecular level investigation of organization in ternary lipid bilayer: a computational approach.
Topics: Cholesterol; Computational Biology; Computer Simulation; Diffusion; G(M1) Ganglioside; Glycosphingolipids; Lipid Bilayers; Lipids; Models, Chemical; Models, Statistical; Molecular Conformation; Phosphatidylcholines; Software; Surface Properties; Time Factors | 2008 |
Binding of ADP in the mitochondrial ADP/ATP carrier is driven by an electrostatic funnel.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding Sites; Computer Simulation; Hydrogen Bonding; Lipid Bilayers; Mitochondrial ADP, ATP Translocases; Mitochondrial Membranes; Models, Molecular; Phosphatidylcholines; Protein Structure, Secondary; Static Electricity; Thermodynamics | 2008 |
Pig skin structure and transdermal delivery of liposomes: a two photon microscopy study.
Topics: Administration, Cutaneous; Animals; Liposomes; Microscopy, Fluorescence, Multiphoton; Models, Biological; Phosphatidylcholines; Skin; Sus scrofa | 2008 |
Interface water dynamics and porating electric fields for phospholipid bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Algorithms; Computer Simulation; Electromagnetic Fields; Electroporation; Image Processing, Computer-Assisted; Lipid Bilayers; Phosphatidylcholines; Phospholipids; Software; Water | 2008 |
Raftlike mixtures of sphingomyelin and cholesterol investigated by solid-state 2H NMR spectroscopy.
Topics: Cholesterol; Deuterium; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Membrane Microdomains; Models, Chemical; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Sphingomyelins | 2008 |
Intra- and intermembrane pairwise molecular recognition between synthetic hydrogen-bonding phospholipids.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Calorimetry; Fluorescence Resonance Energy Transfer; Hydrogen Bonding; Phosphatidylcholines; Phospholipids; Static Electricity; Surface Plasmon Resonance; Thermodynamics; Triazines; Unilamellar Liposomes | 2008 |
Self-assembling micelle-like nanoparticles based on phospholipid-polyethyleneimine conjugates for systemic gene delivery.
Topics: Animals; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Survival; DNA; Gene Expression; Gene Transfer Techniques; Green Fluorescent Proteins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Micelles; Microscopy, Electron; Microscopy, Fluorescence; Nanoparticles; NIH 3T3 Cells; Particle Size; Phosphatidylcholines; Phospholipids; Phosphorylcholine; Plasmids; Polyethyleneimine; Tissue Distribution; Transfection | 2009 |
Formation and characterization of fluid lipid bilayers on alumina.
Topics: Aluminum; Aluminum Oxide; Chemistry; Diffusion; Equipment Design; Lipid Bilayers; Lipids; Microscopy, Fluorescence; Models, Statistical; Oxides; Phosphatidylcholines; Surface Properties; Time Factors; Viscosity | 2008 |
Two protonation switches control rhodopsin activation in membranes.
Topics: Animals; Cattle; Hydrogen Bonding; Membranes, Artificial; Models, Molecular; Phosphatidylcholines; Protein Conformation; Protons; Rhodopsin; Schiff Bases; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Thermodynamics | 2008 |
Molecular dynamics study of a phospholipid monolayer at a water/triglyceride interface: towards lipid emulsion modelling.
Topics: Algorithms; Computational Biology; Computer Simulation; Emulsions; Lipid Bilayers; Models, Chemical; Molecular Conformation; Phosphatidylcholines; Phospholipids; Triglycerides; Water | 2009 |
Interaction of an artificial antimicrobial peptide with lipid membranes.
Topics: Anti-Bacterial Agents; Membranes, Artificial; Microscopy, Atomic Force; Peptides; Phosphatidylcholines; Phosphatidylglycerols | 2009 |
Validation of all-atom phosphatidylcholine lipid force fields in the tensionless NPT ensemble.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Computer Simulation; Membranes, Artificial; Models, Molecular; Phosphatidylcholines | 2009 |
Secondary structure of lipidated Ras bound to a lipid bilayer.
Topics: Acylation; Adsorption; Amides; Kinetics; Lipid Bilayers; Lipids; Models, Molecular; Palmitic Acid; Phosphatidylcholines; Protein Binding; Protein Prenylation; Protein Processing, Post-Translational; Protein Structure, Secondary; Proto-Oncogene Proteins p21(ras); Spectroscopy, Fourier Transform Infrared | 2008 |
Ergosterol increases the intermolecular distance of amphotericin B in the membrane-bound assembly as evidenced by solid-state NMR.
Topics: Amphotericin B; Biophysical Phenomena; Cholesterol; Ergosterol; Ion Channels; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Protein Binding; Spectrophotometry, Ultraviolet; Streptomyces; Ultraviolet Rays | 2008 |
Linking phospholipase mobility to activity by single-molecule wide-field microscopy.
Topics: Biocatalysis; Diffusion; Lipid Bilayers; Microscopy, Fluorescence; Phosphatidylcholines; Phospholipases; Phospholipids | 2009 |
Solubilization of lipid bilayers by myristyl sucrose ester: effect of cholesterol and phospholipid head group size.
Topics: 2-Naphthylamine; Cholesterol; Detergents; Kinetics; Laurates; Lipid Bilayers; Liposomes; Myristic Acid; Phosphatidylcholines; Phospholipids; Quaternary Ammonium Compounds; Solubility; Spectrometry, Fluorescence | 2009 |
Molecular dynamics studies on structure and dynamics of phospholamban monomer and pentamer in membranes.
Topics: Animals; Calcium-Binding Proteins; Computer Simulation; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Models, Molecular; Phosphatidylcholines; Phosphorylation; Protein Conformation; Protein Multimerization; Protein Structure, Tertiary; Rabbits | 2009 |
Membrane-bound conformation of Naja nigricollis toxin gamma affects its membrane-damaging activity.
Topics: Animals; Cell Membrane; Elapid Venoms; Fluorescence; Micelles; Phosphatidylcholines; Protein Conformation; Spectroscopy, Fourier Transform Infrared | 2009 |
Imaging of phosphatidylcholines in the adult rat brain using MALDI-TOF MS.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Brain; Brain Chemistry; Brain Mapping; Cell Membrane; Cerebellum; Cerebral Cortex; Male; Nerve Fibers, Myelinated; Neurochemistry; Neurons; Olfactory Bulb; Olfactory Pathways; Phosphatidylcholines; Rats; Rats, Wistar; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2009 |
Covalent conjugation of tetrameric bovine liver catalase to liposome membranes for stabilization of the enzyme tertiary and quaternary structures.
Topics: Animals; Catalase; Cattle; Enzyme Stability; Hot Temperature; Liposomes; Liver; Phosphatidylcholines; Phosphatidylethanolamines; Protein Structure, Quaternary; Protein Structure, Tertiary; Spectrometry, Fluorescence | 2009 |
Films of agarose enable rapid formation of giant liposomes in solutions of physiologic ionic strength.
Topics: Biophysical Phenomena; Buffers; Cholesterol; Liposomes; Osmolar Concentration; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Sepharose; Sodium Chloride; Spectrometry, Fluorescence | 2009 |
Thermal stability of apolipoprotein A-I in high-density lipoproteins by molecular dynamics.
Topics: Apolipoprotein A-I; Computer Simulation; Humans; Lipid Bilayers; Lipoproteins, HDL; Models, Biological; Models, Molecular; Phosphatidylcholines; Protein Denaturation; Protein Folding; Protein Stability; Protein Structure, Quaternary; Protein Structure, Secondary; Temperature | 2009 |
Effect of membrane composition on antimicrobial peptides aurein 2.2 and 2.3 from Australian southern bell frogs.
Topics: Animals; Anti-Infective Agents; Antimicrobial Cationic Peptides; Anura; Benzothiazoles; Carbocyanines; Cell Membrane; Cell Membrane Permeability; Dimyristoylphosphatidylcholine; Fluoresceins; Gramicidin; Lipid Bilayers; Membrane Potentials; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary; Staphylococcus aureus | 2009 |
Viewing the bilayer hydrocarbon core using neutron diffraction.
Topics: Hydrocarbons; Lipid Bilayers; Neutron Diffraction; Phosphatidylcholines | 2009 |
Initial response of the potassium channel voltage sensor to a transmembrane potential.
Topics: Ion Channel Gating; Kinetics; Kv1.2 Potassium Channel; Lipid Bilayers; Membrane Potentials; Models, Molecular; Phosphatidylcholines; Protein Conformation; Protein Structure, Tertiary; Static Electricity; Thermodynamics | 2009 |
Mass spectrometric determination of apolipoprotein molecular stoichiometry in reconstituted high density lipoprotein particles.
Topics: Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins; Apolipoproteins A; Blood Chemical Analysis; Blood Protein Electrophoresis; Cross-Linking Reagents; Dimyristoylphosphatidylcholine; Electrophoresis, Polyacrylamide Gel; Humans; In Vitro Techniques; Lipoproteins, HDL; Liposomes; Phosphatidylcholines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2009 |
Biophysical characterization of a new phospholipid analogue with a spin-labeled unsaturated fatty acyl chain.
Topics: Biophysical Phenomena; Cell Membrane; Electron Spin Resonance Spectroscopy; Fatty Acids; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Spin Labels | 2009 |
Structure and membrane interactions of the antibiotic peptide dermadistinctin K by multidimensional solution and oriented 15N and 31P solid-state NMR spectroscopy.
Topics: Animals; Antimicrobial Cationic Peptides; Anura; Circular Dichroism; Lipid Bilayers; Micelles; Models, Molecular; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phosphorus Isotopes; Phosphorylcholine; Protein Conformation; Sodium Dodecyl Sulfate; Trifluoroethanol; Unilamellar Liposomes; Water | 2009 |
The role played by lipids unsaturation upon the membrane interaction of the Helicobacter pylori HP(2-20) antimicrobial peptide analogue HPA3.
Topics: Antimicrobial Cationic Peptides; Electrophysiology; Helicobacter pylori; Lipid Bilayers; Molecular Structure; Peptide Fragments; Phosphatidylcholines; Ribosomal Proteins; Spectrometry, Fluorescence | 2009 |
Membrane insertion of the FYVE domain is modulated by pH.
Topics: Binding Sites; Histidine; Humans; Hydrogen-Ion Concentration; Membrane Lipids; Models, Molecular; Mutation; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositol Phosphates; Protein Binding; Protein Interaction Domains and Motifs; Vesicular Transport Proteins | 2009 |
The calcium-dependent and calcium-independent membrane binding of synaptotagmin 1: two modes of C2B binding.
Topics: Animals; Calcium; Computer Simulation; Electron Spin Resonance Spectroscopy; Kinetics; Lipid Bilayers; Membranes, Artificial; Models, Molecular; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Synaptotagmin I; Water | 2009 |
Perturbations of membrane structure by cholesterol and cholesterol derivatives are determined by sterol orientation.
Topics: Cholesterol; Compressive Strength; Computer Simulation; Elasticity; Hydrogen Bonding; Hydroxycholesterols; Lipid Bilayers; Models, Biological; Models, Molecular; Molecular Structure; Oxidation-Reduction; Phosphatidylcholines | 2009 |
Macroscopic domain formation during cooling in the platelet plasma membrane: an issue of low cholesterol content.
Topics: Blood Platelets; Cell Membrane; Cholesterol; Humans; Lecithins; Liposomes; Microscopy, Fluorescence; Models, Biological; Phosphatidylcholines; Phosphatidylinositols; Phosphatidylserines; Spectroscopy, Fourier Transform Infrared; Sphingomyelins; Thermodynamics | 2009 |
Sorting of lipids and proteins in membrane curvature gradients.
Topics: Animals; Biomechanical Phenomena; Carbocyanines; Cattle; Cell Membrane; Cholera Toxin; Fluorescence; Fluorescence Recovery After Photobleaching; Fluorescent Dyes; Intracellular Membranes; Lipid Metabolism; Microspheres; Phosphatidylcholines; Proteins; Unilamellar Liposomes | 2009 |
Lipid gymnastics: evidence of complete acyl chain reversal in oxidized phospholipids from molecular simulations.
Topics: Electrons; Lipid Bilayers; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Static Electricity | 2009 |
Solid-state NMR and molecular dynamics characterization of cannabinoid receptor-1 (CB1) helix 7 conformational plasticity in model membranes.
Topics: Amino Acid Sequence; Biophysical Phenomena; Circular Dichroism; Dimyristoylphosphatidylcholine; Humans; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Protein Structure, Secondary; Receptor, Cannabinoid, CB1; Thermodynamics | 2009 |
Monitoring detergent-mediated solubilization and reconstitution of lipid membranes by isothermal titration calorimetry.
Topics: Calorimetry; Detergents; Membranes, Artificial; Micelles; Phosphatidylcholines; Solubility; Titrimetry; Unilamellar Liposomes | 2009 |
Lipid raft composition modulates sphingomyelinase activity and ceramide-induced membrane physical alterations.
Topics: Bacillus cereus; Ceramides; Cholesterol; Fluorescence Polarization; Fluorescence Resonance Energy Transfer; Hydrolysis; Liposomes; Membrane Microdomains; Phosphatidylcholines; Sphingomyelin Phosphodiesterase; Sphingomyelins | 2009 |
HIV-1 Nef perturbs artificial membranes: investigation of the contribution of the myristoyl anchor.
Topics: Amino Acid Sequence; Electrophoresis, Polyacrylamide Gel; HIV-1; Microscopy, Atomic Force; Microscopy, Fluorescence; Molecular Sequence Data; nef Gene Products, Human Immunodeficiency Virus; Phosphatidylcholines; Photomicrography; Protein Binding; Silicon Dioxide; Unilamellar Liposomes | 2009 |
Transmembrane helical domain of the cannabinoid CB1 receptor.
Topics: Binding Sites; Computer Simulation; Conserved Sequence; Crystallography, X-Ray; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Models, Molecular; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptor, Cannabinoid, CB1; Receptors, Adrenergic, beta-2; Software; Water | 2009 |
Assigning membrane binding geometry of cytochrome C by polarized light spectroscopy.
Topics: Animals; Cardiolipins; Circular Dichroism; Cytochromes c; Horses; Light; Lipid Bilayers; Models, Molecular; Myocardium; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Structure, Secondary; Spectrum Analysis | 2009 |
Characterisation of RC-proteoliposomes at different RC/lipid ratios.
Topics: Kinetics; Light; Lipids; Micelles; Phosphatidylcholines; Photosynthetic Reaction Center Complex Proteins; Proteolipids; Scattering, Radiation; Spectroscopy, Fourier Transform Infrared | 2009 |
Intrinsic potential of cell membranes: opposite effects of lipid transmembrane asymmetry and asymmetric salt ion distribution.
Topics: Cell Membrane; Glycerophospholipids; Membrane Potentials; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; Potassium Chloride; Pressure; Sodium Chloride; Static Electricity; Temperature; Time Factors | 2009 |
Mechanism of membrane permeabilization by a bacterial trehalose lipid biosurfactant produced by Rhodococcus sp.
Topics: Calorimetry; Glycolipids; Molecular Structure; Phosphatidylcholines; Rhodococcus; Spectrometry, Fluorescence; Surface-Active Agents; Trehalose | 2009 |
Evidence of pores and thinned lipid bilayers induced in oriented lipid membranes interacting with the antimicrobial peptides, magainin-2 and aurein-3.3.
Topics: Anisotropy; Antimicrobial Cationic Peptides; Cholesterol; Lipid Bilayers; Magainins; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Porosity; Xenopus Proteins | 2009 |
Stiffening effect of cholesterol on disordered lipid phases: a combined neutron spin echo + dynamic light scattering analysis of the bending elasticity of large unilamellar vesicles.
Topics: Algorithms; Cholesterol; Elasticity; Light; Membrane Fluidity; Phosphatidylcholines; Scattering, Radiation; Thermodynamics; Unilamellar Liposomes | 2009 |
A comparison of the membrane binding properties of C1B domains of PKCgamma, PKCdelta, and PKCepsilon.
Topics: Adenosine; Calorimetry, Differential Scanning; Cell Line; Diglycerides; Fluorescence Resonance Energy Transfer; Glycerophospholipids; Humans; Models, Molecular; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Protein Binding; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Structure, Tertiary; Temperature; Unilamellar Liposomes | 2009 |
The effect of a C-terminal peptide of surfactant protein B (SP-B) on oriented lipid bilayers, characterized by solid-state 2H- and 31P-NMR.
Topics: Animals; Cattle; Deuterium; Lipid Bilayers; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Phosphorus Isotopes; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Proteins | 2009 |
Interfacial mechanism of phospholipase A2: pH-dependent inhibition and Me-beta-cyclodextrin activation.
Topics: Animals; beta-Cyclodextrins; Catalysis; Elapid Venoms; Enzyme Activation; Hydrogen-Ion Concentration; Hydrolysis; Lipid Bilayers; Neutron Diffraction; Phosphatidylcholines; Phospholipase A2 Inhibitors; Phospholipases A2; Solubility; Substrate Specificity | 2009 |
Anionic lipid and cholesterol interactions with alpha4beta2 nAChR: insights from MD simulations.
Topics: Adenosine; Cholesterol; Glycerophospholipids; Lipid Metabolism; Lipids; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Receptors, Nicotinic | 2009 |
Visualization of phospholipid particle fusion induced by duramycin.
Topics: Bacteriocins; Microscopy, Scanning Tunneling; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids | 2009 |
Characterization of membrane-protein interactions for the leucine transporter from Aquifex aeolicus by molecular dynamics calculations.
Topics: Bacteria; Dimyristoylphosphatidylcholine; Lipid Bilayers; Membrane Proteins; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines | 2009 |
Atomistic simulations of phosphatidylcholines and cholesteryl esters in high-density lipoprotein-sized lipid droplet and trilayer: clues to cholesteryl ester transport and storage.
Topics: Biological Transport; Cell Membrane; Cholesterol Esters; Intracellular Space; Lipoproteins, HDL; Models, Biological; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Solubility; Surface Properties | 2009 |
Visualization of membrane loss during the shrinkage of giant vesicles under electropulsation.
Topics: Electricity; Electrodes; Hydrogen-Ion Concentration; Movement; Permeability; Phosphatidylcholines; Porosity; Unilamellar Liposomes | 2009 |
Cholesterol modulates the exposure and orientation of pulmonary surfactant protein SP-C in model surfactant membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Amides; Deuterium Exchange Measurement; Lipid Bilayers; Phosphatidylcholines; Phosphatidylglycerols; Principal Component Analysis; Protein Structure, Secondary; Protein Structure, Tertiary; Pulmonary Surfactant-Associated Protein C; Pulmonary Surfactants; Spectroscopy, Fourier Transform Infrared | 2009 |
Growth and shape transformations of giant phospholipid vesicles upon interaction with an aqueous oleic acid suspension.
Topics: Fluorescent Dyes; Hydrogen-Ion Concentration; Oleic Acid; Phosphatidylcholines; Phospholipids; Pyrenes; Spectrometry, Fluorescence; Unilamellar Liposomes; Water | 2009 |
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine improves cognitive decline by enhancing long-term depression.
Topics: Aged; Aged, 80 and over; Animals; Central Nervous System Agents; Cognition Disorders; Dementia; Excitatory Postsynaptic Potentials; Female; Hippocampus; Humans; In Vitro Techniques; Long-Term Synaptic Depression; Male; Maze Learning; Middle Aged; Phosphatidylcholines; Psychiatric Status Rating Scales; Rats; Rats, Wistar; Receptors, AMPA | 2009 |
Dynamic conformational responses of a human cannabinoid receptor-1 helix domain to its membrane environment.
Topics: Dimyristoylphosphatidylcholine; Electron Spin Resonance Spectroscopy; Humans; Lipid Bilayers; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphatidylcholines; Phospholipids; Protein Structure, Secondary; Protein Structure, Tertiary; Receptor, Cannabinoid, CB1; Signal Transduction; Spin Trapping; Thermodynamics; Trifluoroethanol | 2009 |
Molecular model of a cell plasma membrane with an asymmetric multicomponent composition: water permeation and ion effects.
Topics: Cell Membrane; Cell Membrane Permeability; Computer Simulation; Membranes, Artificial; Models, Chemical; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Potassium; Potassium Chloride; Sodium; Sodium Chloride; Sphingomyelins; Static Electricity; Time Factors; Water | 2009 |
Effects of lipid composition and phase on the membrane interaction of the prion peptide 106-126 amide.
Topics: Cell Membrane Permeability; Circular Dichroism; Detergents; Linear Models; Lipid Bilayers; Microscopy, Atomic Force; Models, Chemical; Octoxynol; Peptide Fragments; Permeability; Phase Transition; Phosphatidylcholines; Prions; Sphingomyelins | 2009 |
Energetics of ErbB1 transmembrane domain dimerization in lipid bilayers.
Topics: Algorithms; Circular Dichroism; Detergents; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Fluorescein; Lipid Bilayers; Phosphatidylcholines; Protein Multimerization; Protein Stability; Protein Structure, Secondary; Rhodamines; Signal Transduction; Spectrometry, Fluorescence | 2009 |
Directed formation of lipid membrane microdomains as high affinity sites for His-tagged proteins.
Topics: Animals; Carrier Proteins; Copper; Histidine; Imino Acids; Lipid Metabolism; Lipids; Maltose-Binding Proteins; Membrane Microdomains; Membranes, Artificial; Phosphatidylcholines; Proteins | 2009 |
Structural implications of mutations assessed by molecular dynamics: Vpu1-32 from HIV-1.
Topics: HIV-1; Human Immunodeficiency Virus Proteins; Kinetics; Lipid Bilayers; Molecular Dynamics Simulation; Mutation, Missense; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Viral Regulatory and Accessory Proteins | 2010 |
The interaction of the Bax C-terminal domain with membranes is influenced by the presence of negatively charged phospholipids.
Topics: bcl-2-Associated X Protein; Carbon Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Protein Structure, Tertiary; Spectrometry, Fluorescence | 2009 |
Calcein permeation across phosphatidylcholine bilayer membrane: effects of membrane fluidity, liposome size, and immobilization.
Topics: Biological Transport; Cell Membrane Permeability; Fluoresceins; Lipid Bilayers; Liposomes; Membrane Fluidity; Membrane Lipids; Membranes, Artificial; Permeability; Phosphatidylcholines; Temperature | 2009 |
Molecular binding of catechins to biomembranes: relationship to biological activity.
Topics: Catechin; Cell Membrane; Hydrogen Bonding; Lipid Bilayers; Models, Biological; Phosphatidylcholines | 2009 |
Coupling molecular dynamics simulations with experiments for the rational design of indolicidin-analogous antimicrobial peptides.
Topics: Anti-Infective Agents; Antimicrobial Cationic Peptides; Computer Simulation; Hemolysis; Humans; Lipid Bilayers; Models, Molecular; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Static Electricity | 2009 |
Phospholipid reorientation at the lipid/water interface measured by high resolution 31P field cycling NMR spectroscopy.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Cattle; Cholesterol; Dimyristoylphosphatidylcholine; Motion; Nuclear Magnetic Resonance, Biomolecular; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Phosphorus Isotopes; Sphingomyelins; Temperature; Unilamellar Liposomes; Water | 2009 |
Direct visualization of the lateral structure of porcine brain cerebrosides/POPC mixtures in presence and absence of cholesterol.
Topics: Animals; Brain; Calorimetry, Differential Scanning; Cerebrosides; Cholesterol; Cold Temperature; Lipid Bilayers; Microscopy, Confocal; Microscopy, Fluorescence, Multiphoton; Phase Transition; Phosphatidylcholines; Spectroscopy, Fourier Transform Infrared; Swine; Temperature; Unilamellar Liposomes | 2009 |
Molecular dynamics simulations of PIP2 and PIP3 in lipid bilayers: determination of ring orientation, and the effects of surface roughness on a Poisson-Boltzmann description.
Topics: Chlorides; Computer Simulation; Lipid Bilayers; Models, Chemical; Models, Molecular; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Sodium; Static Electricity; Surface Properties; Time Factors | 2009 |
Ligand extraction properties of the GM2 activator protein and its interactions with lipid vesicles.
Topics: Cholesterol; Chromatography, Gel; Dansyl Compounds; G(M2) Activator Protein; Gangliosides; Hydrogen-Ion Concentration; Lipid Bilayers; Liposomes; Lysophospholipids; Models, Chemical; Models, Molecular; Monoglycerides; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Phospholipids; Spectrometry, Fluorescence; Sucrose; Unilamellar Liposomes | 2009 |
Characterization of heat-induced interaction of neutral liposome with lipid membrane of Streptomyces griseus cell.
Topics: Adsorption; Endocytosis; Heat-Shock Response; Hot Temperature; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Lipid Bilayers; Liposomes; Microscopy, Fluorescence; Phosphatidylcholines; Rhodamines; Spectrophotometry, Infrared; Staining and Labeling; Streptomyces griseus; Surface Properties; Water | 2009 |
A layer model of ethanol partitioning into lipid membranes.
Topics: Chromatography, Gas; Ethanol; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Models, Biological; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Phosphatidylserines; Sphingomyelins; Water | 2009 |
Water replacement hypothesis in atomic detail--factors determining the structure of dehydrated bilayer stacks.
Topics: Lipid Bilayers; Models, Molecular; Nitrogen; Phosphatidylcholines; Phosphorus; Reproducibility of Results; Time Factors; Trehalose; Water | 2009 |
Assembly of Coenzyme Q10 nanostructure resembling nascent discoidal high density lipoprotein particle.
Topics: Apolipoprotein A-I; Lipoproteins, HDL; Nanoparticles; Particle Size; Phosphatidylcholines; Solubility; Ubiquinone; Water | 2009 |
Surfactant protein SP-B strongly modifies surface collapse of phospholipid vesicles: insights from a quartz crystal microbalance with dissipation.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Cytological Techniques; Lipid Bilayers; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Pulmonary Surfactant-Associated Protein B; Silicon Dioxide; Swine; Unilamellar Liposomes | 2009 |
Comparative molecular dynamics simulation studies of protegrin-1 monomer and dimer in two different lipid bilayers.
Topics: Antimicrobial Cationic Peptides; Computer Simulation; Guanidine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Models, Chemical; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Protein Multimerization; Protein Stability; Protein Structure, Secondary; Rotation; Water | 2009 |
The oxidized form of cholesterol 3beta-hydroxy-5-oxo-5,6-secocholestan-6-al induces structural and thermotropic changes in phospholipid membranes.
Topics: Calorimetry, Differential Scanning; Lipid Bilayers; Membranes; Phosphatidylcholines; Phospholipids; Temperature; Thermodynamics; Water; X-Ray Diffraction | 2009 |
Microelectrophoresis in a laser trap: a platform for measuring electrokinetic interactions and flow properties within microstructures.
Topics: Algorithms; Calibration; Elasticity; Electricity; Electrophoresis; Kinetics; Lasers; Linear Models; Lipid Bilayers; Microfluidics; Microspheres; Microtechnology; Optics and Photonics; Osmosis; Phosphatidylcholines; Silicon Dioxide | 2009 |
Amphotericin B-induced ion flux is markedly attenuated in phosphatidylglycerol membrane as evidenced by a newly devised fluorometric method.
Topics: Amphotericin B; Antifungal Agents; Fluorescent Dyes; Fluorometry; Ion Transport; Liposomes; Permeability; Phosphatidylcholines; Phosphatidylglycerols | 2009 |
Fluconazole modulates membrane rigidity, heterogeneity, and water penetration into the plasma membrane in Saccharomyces cerevisiae.
Topics: Antifungal Agents; Cell Membrane Permeability; Drug Resistance, Fungal; Fluconazole; Fluorescence Polarization; Gene Deletion; Membrane Fluidity; Oxidoreductases; Phosphatidylcholines; Saccharomyces cerevisiae; Water | 2009 |
Alamethicin topology in phospholipid membranes by oriented solid-state NMR and EPR spectroscopies: a comparison.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Alamethicin; Animals; Electron Spin Resonance Spectroscopy; Electrons; Lipids; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Peptides; Phosphatidylcholines; Phospholipids; Spin Labels; Surface Properties; Trichoderma | 2009 |
Giant vesicles under oxidative stress induced by a membrane-anchored photosensitizer.
Topics: Computer Simulation; Fluorescence; Light; Lipid Bilayers; Microscopy, Fluorescence; Models, Chemical; Oxidative Stress; Oxygen; Phosphatidylcholines; Phosphatidylethanolamines; Photosensitizing Agents; Porphyrins; Time Factors; Unilamellar Liposomes | 2009 |
Interactions of the GM2 activator protein with phosphatidylcholine bilayers: a site-directed spin-labeling power saturation study.
Topics: Chelating Agents; Electron Spin Resonance Spectroscopy; G(M2) Activator Protein; Lipid Bilayers; Models, Chemical; Models, Molecular; Mutation; Nickel; Phosphatidylcholines; Recombinant Proteins; Spin Labels; Water | 2009 |
Photocurrent generation from Ru(bpy)3(2+) immobilized on phospholipid/alkanethiol hybrid bilayers.
Topics: 2,2'-Dipyridyl; Alkanes; Electric Capacitance; Electric Conductivity; Electrodes; Gold; Lipid Bilayers; Membranes, Artificial; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Ruthenium; Sulfhydryl Compounds | 2009 |
Triggered instability of liposomes bound to hydrophobically modified core-shell PNIPAM hydrogel beads.
Topics: Acrylamides; Acrylates; Acrylic Resins; Hydrogel, Polyethylene Glycol Dimethacrylate; Liposomes; Magnetic Resonance Spectroscopy; Models, Theoretical; Phosphatidylcholines; Polymers | 2010 |
Cause and effect of melittin-induced pore formation: a computational approach.
Topics: Amino Acid Sequence; Cell Membrane; Cell Membrane Permeability; Chlorides; Computer Simulation; Dose-Response Relationship, Drug; Hydrophobic and Hydrophilic Interactions; Ion Channels; Lipid Bilayers; Melitten; Molecular Dynamics Simulation; Molecular Sequence Data; Movement; Phosphatidylcholines; Porosity; Protein Multimerization; Protein Stability; Protein Structure, Quaternary; Solvents; Substrate Specificity; Water | 2009 |
Preparation of reconstituted acetylcholine receptor membranes suitable for AFM imaging of lipid-protein interactions.
Topics: Calcium; Lipid Bilayers; Microscopy, Atomic Force; Models, Molecular; Phosphatidylcholines; Protein Binding; Proteins; Proteolipids; Receptors, Nicotinic | 2010 |
Protein contents in biological membranes can explain abnormal solvation of charged and polar residues.
Topics: Amino Acid Sequence; Amino Acids; Biophysical Phenomena; Electrochemistry; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Membrane Proteins; Membranes, Artificial; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Protein Structure, Secondary; Thermodynamics; Water | 2009 |
Assessment of the multiphase interaction between a membrane disrupting peptide and a lipid membrane.
Topics: Kinetics; Melitten; Membrane Lipids; Models, Chemical; Phosphatidylcholines; Protein Binding; Surface Plasmon Resonance | 2009 |
Conformational and dynamics simulation study of antimicrobial peptide hedistin-heterogeneity of its helix-turn-helix motif.
Topics: Animals; Anti-Infective Agents; Helix-Loop-Helix Motifs; Lipid Bilayers; Methicillin Resistance; Peptides; Phosphatidylcholines; Polychaeta; Staphylococcus aureus; Vibrio alginolyticus | 2009 |
Membrane chemical stability and seed longevity.
Topics: Carbohydrates; Cell Membrane; Cyclic N-Oxides; Desiccation; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Onions; Phosphatidylcholines; Seeds; Solanum lycopersicum; Spectroscopy, Fourier Transform Infrared; Temperature | 2010 |
Permeabilization of biological and artificial membranes by a bacterial dirhamnolipid produced by Pseudomonas aeruginosa.
Topics: Cell Membrane; Cell Shape; Cholesterol; Erythrocytes; Fluoresceins; Glycolipids; Hemoglobins; Hemolysis; Humans; Kinetics; Lysophosphatidylcholines; Membranes, Artificial; Permeability; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; Potassium; Pseudomonas aeruginosa; Unilamellar Liposomes | 2010 |
Small discoidal pre-beta1 HDL particles are efficient acceptors of cell cholesterol via ABCA1 and ABCG1.
Topics: Alitretinoin; Animals; Apolipoprotein A-I; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Cell Line, Tumor; Cells, Cultured; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Cyclic AMP; Cyclopentanes; Fibroblasts; High-Density Lipoproteins, Pre-beta; Humans; Kinetics; Macrophages; Mice; Particle Size; Phosphatidylcholines; Probucol; Rats; Scavenger Receptors, Class B; Tangier Disease; Thiosemicarbazones; Transfection; Tretinoin | 2009 |
Fine-tuning of POPC liposomal leakage by the use of beta-cyclodextrin and several hydrophobic guests.
Topics: beta-Cyclodextrins; Drug Stability; Hydrophobic and Hydrophilic Interactions; Kinetics; Liposomes; Microscopy, Electron, Transmission; Phosphatidylcholines; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2010 |
Lipid domains and mechanical plasticity of Escherichia coli lipid monolayers.
Topics: Elasticity; Escherichia coli; Lipids; Phosphatidylcholines; Stress, Mechanical | 2010 |
Interactions of KLA amphipathic model peptides with lipid monolayers.
Topics: Amino Acid Sequence; Antimicrobial Cationic Peptides; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary; Spectrophotometry, Infrared | 2009 |
Effect of ceramide on nonraft proteins.
Topics: Ceramides; Lipid Bilayers; Liposomes; Membrane Proteins; Microscopy, Fluorescence; Models, Biological; Phosphatidylcholines; Sphingomyelins; X-Ray Diffraction | 2009 |
HDL superphospholipidation enhances key steps in reverse cholesterol transport.
Topics: Cholesterol; Chromatography, Gel; Humans; Lipoproteins, HDL; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines | 2010 |
Chapter 11 - Reconstitution of membrane proteins in phospholipid bilayer nanodiscs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bacteriorhodopsins; Crystallography, X-Ray; Lipid Bilayers; Membrane Proteins; Mice; Models, Biological; Nanostructures; Phosphatidylcholines; Phospholipids | 2009 |
Fluctuation dynamics of spherical vesicles: frustration of regular bulk dissipation into subdiffusive relaxation.
Topics: Cell Membrane; Diffusion; Light; Lipid Bilayers; Neutron Diffraction; Phosphatidylcholines; Scattering, Radiation | 2009 |
Oxidative/heat stress enhanced production of chitosanase from Streptomyces griseus cells through its interaction with liposome.
Topics: Adsorption; Cell Membrane; Cell Membrane Permeability; Circular Dichroism; Glycoside Hydrolases; Hot Temperature; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Lipid Bilayers; Liposomes; Membrane Fluidity; Membranes, Artificial; Oxidation-Reduction; Oxidative Stress; Oxides; Permeability; Phosphatidylcholines; Solubility; Streptomyces griseus; Stress, Physiological | 2009 |
Phase separation in binary mixtures of bipolar and monopolar lipid dispersions revealed by 2H NMR spectroscopy, small angle x-ray scattering, and molecular theory.
Topics: Deuterium; Lipid Bilayers; Models, Chemical; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phospholipid Ethers; Scattering, Small Angle; Temperature; X-Ray Diffraction | 2009 |
Pulmonary surfactant protein SP-C counteracts the deleterious effects of cholesterol on the activity of surfactant films under physiologically relevant compression-expansion dynamics.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Air; Animals; Calorimetry, Differential Scanning; Cholesterol; Lipid Bilayers; Phase Transition; Phosphatidylcholines; Phosphatidylglycerols; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Protein C; Surface Tension; Swine; Thermodynamics; Time Factors | 2009 |
Orientation of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine at the surface of formamide and hydroxypropionitrile.
Topics: Formamides; Nitriles; Phosphatidylcholines; Surface Properties | 2010 |
In vivo administration of BL-3050: highly stable engineered PON1-HDL complexes.
Topics: Animals; Aryldialkylphosphatase; Chlorpyrifos; Disease Models, Animal; Enzyme Stability; Female; Glutathione; Humans; Injections, Intravenous; Lipoproteins, HDL; Male; Mice; Mice, Inbred C57BL; Organophosphates; Phosphatidylcholines; Protein Engineering; Recombinant Proteins | 2009 |
Partition of amphiphilic molecules to lipid bilayers by isothermal titration calorimetry.
Topics: Calorimetry; Lipid Bilayers; Phosphatidylcholines; Sodium Dodecyl Sulfate | 2010 |
Evaluation of liposome-water partitioning for predicting bioaccumulation potential of hydrophobic organic chemicals.
Topics: Adsorption; Benzopyrenes; Hydrophobic and Hydrophilic Interactions; Liposomes; Organic Chemicals; Phenanthrenes; Phosphatidylcholines; Reproducibility of Results; Solid Phase Microextraction; Temperature; Water | 2009 |
LyeTx I, a potent antimicrobial peptide from the venom of the spider Lycosa erythrognatha.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antimicrobial Cationic Peptides; Candida; Cryptococcus neoformans; Dose-Response Relationship, Drug; Escherichia coli; Microbial Sensitivity Tests; Models, Molecular; Phosphatidylcholines; Protein Structure, Secondary; Spider Venoms; Spiders; Staphylococcus aureus | 2010 |
Structures of discoidal high density lipoproteins: a combined computational-experimental approach.
Topics: Apolipoprotein A-I; Circular Dichroism; Computational Biology; Humans; Lipoproteins; Lipoproteins, HDL; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Dynamics Simulation; Mutation; Phosphatidylcholines | 2010 |
Phase coexistence in a triolein-phosphatidylcholine system. Implications for lysosomal membrane properties.
Topics: Calorimetry, Differential Scanning; Electron Spin Resonance Spectroscopy; Glycerides; Lipid Bilayers; Lysosomes; Membrane Fluidity; Phase Transition; Phosphatidylcholines; Transition Temperature; Triolein; Water | 2010 |
Interactions of nanoparticles with lipid vesicles: a population based computer aided image analysis approach.
Topics: Biomedical Engineering; Fullerenes; Image Processing, Computer-Assisted; Liposomes; Nanoparticles; Particle Size; Phosphatidylcholines | 2009 |
An optimized negative-staining protocol of electron microscopy for apoE4 POPC lipoprotein.
Topics: Apolipoprotein E4; Artifacts; Buffers; Microscopy, Electron; Negative Staining; Particle Size; Phosphatidylcholines | 2010 |
Impact of phospholipid bilayer saturation on amyloid-beta protein aggregation intermediate growth: a quartz crystal microbalance analysis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Fatty Acids; Lipid Bilayers; Liposomes; Peptide Fragments; Phenylenediamines; Phosphatidylcholines; Phospholipids; Quartz | 2010 |
Influence of phase separating lipids on supported lipid bilayer formation at SiO2 surfaces.
Topics: Cholesterol; Lipid Bilayers; Microscopy, Fluorescence; Phosphatidylcholines; Phosphorylcholine; Silicon Dioxide; Sphingosine; Surface Properties; Temperature | 2010 |
Dual functions of the human antimicrobial peptide LL-37-target membrane perturbation and host cell cargo delivery.
Topics: Animals; Antimicrobial Cationic Peptides; Cathelicidins; Cell Membrane; Chlorocebus aethiops; Cholesterol; COS Cells; Drug Delivery Systems; Fluoresceins; Fluorescent Dyes; Humans; Oligonucleotides; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary; Unilamellar Liposomes | 2010 |
Hyperforin induces Ca(2+)-independent arachidonic acid release in human platelets by facilitating cytosolic phospholipase A(2) activation through select phospholipid interactions.
Topics: Arachidonic Acid; Blood Platelets; Bridged Bicyclo Compounds; Calcium; Cytosol; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Magnetic Resonance Spectroscopy; p38 Mitogen-Activated Protein Kinases; Phloroglucinol; Phosphatidylcholines; Phospholipases A2; Phosphorylation; Pyridines; Terpenes | 2010 |
The role of the disulfide bond in the interaction of islet amyloid polypeptide with membranes.
Topics: Amino Acid Sequence; Amyloid; Cell Membrane; Disulfides; Humans; Islets of Langerhans; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Structure, Secondary | 2010 |
Thermodynamic and structural behaviour of equimolar POPC/CnE4 (n=8, 12, 16) mixtures by sorption gravimetry, 2H NMR spectroscopy and X-ray diffraction.
Topics: Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Structure; Phosphatidylcholines; Thermodynamics; X-Ray Diffraction | 2010 |
Characterization of electronic properties in complex molecular systems: modeling of a micropolarity probe.
Topics: Algorithms; Models, Chemical; Molecular Dynamics Simulation; Phosphatidylcholines; Pyrenes; Quantum Theory | 2010 |
Design of a soluble transmembrane helix for measurements of water-membrane partitioning.
Topics: Amino Acid Sequence; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Folding; Thermodynamics; Water | 2010 |
Lipid bilayer blanketing versus penetrating silica colloidal crystals.
Topics: Colloids; Crystallization; Lipid Bilayers; Particle Size; Phosphatidylcholines; Silicon Dioxide; Surface Properties; Time Factors | 2010 |
The role of calcium ions in the interactions of PrP106-126 amide with model membranes.
Topics: Amides; Calcium; Circular Dichroism; Lipid Bilayers; Membranes, Artificial; Microscopy, Atomic Force; Models, Theoretical; Phosphatidylcholines; Prions; Protein Structure, Secondary; Sphingomyelins; Static Electricity | 2010 |
Electrodeless QCM-D for lipid bilayer applications.
Topics: Biosensing Techniques; Electrodes; Equipment Design; Equipment Failure Analysis; Lipid Bilayers; Micro-Electrical-Mechanical Systems; Phosphatidylcholines | 2011 |
Interactions of alamethicin with model cell membranes investigated using sum frequency generation vibrational spectroscopy in real time in situ.
Topics: Alamethicin; Dimyristoylphosphatidylcholine; Lipid Bilayers; Models, Molecular; Phosphatidylcholines; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Vibration | 2010 |
Octafluorocalix[4]pyrrole: a chloride/bicarbonate antiport agent.
Topics: Anions; Bicarbonates; Calixarenes; Chloride-Bicarbonate Antiporters; Lipid Bilayers; Nitrates; Phosphatidylcholines; Porphyrins; Sodium Chloride; Sulfates | 2010 |
Spatial-resolution limits in mass spectrometry imaging of supported lipid bilayers and individual lipid vesicles.
Topics: Gold; Lipid Bilayers; Liposomes; Phosphatidylcholines; Silicon Dioxide; Spectrometry, Mass, Secondary Ion | 2010 |
Reactivity and fusion between cationic vesicles and fatty acid anionic vesicles.
Topics: Models, Chemical; Oleic Acid; Osmolar Concentration; Phosphatidylcholines; Quaternary Ammonium Compounds; Surface-Active Agents | 2010 |
Effect of α-helical peptides on liposome structure: a comparative study of melittin and alamethicin.
Topics: Alamethicin; Liposomes; Melitten; Molecular Structure; Particle Size; Phosphatidylcholines; Surface Properties | 2010 |
Vesicle adsorption and phospholipid bilayer formation on topographically and chemically nanostructured surfaces.
Topics: Adsorption; Animals; Cattle; Gold; Kinetics; Lipid Bilayers; Microscopy, Atomic Force; Nanostructures; Phosphatidylcholines; Serum Albumin, Bovine; Silicon Dioxide; Surface Properties | 2010 |
Liposome destabilization by a 2,7-diazapyrenium derivative through formation of transient pores in the lipid bilayer.
Topics: Chromatography, Gel; Fluoresceins; Kinetics; Lipid Bilayers; Liposomes; Molecular Dynamics Simulation; Phenanthrolines; Phosphatidylcholines; Physical Phenomena; Porosity; Rotation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Water | 2010 |
Antimicrobial and membrane disrupting activities of a peptide derived from the human cathelicidin antimicrobial peptide LL37.
Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Calorimetry, Differential Scanning; Cathelicidins; Cell Membrane; Cholesterol; Circular Dichroism; Dimyristoylphosphatidylcholine; Escherichia coli; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Lipid Bilayers; Liposomes; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phase Transition; Phosphatidylcholines; Phosphatidylglycerols; Phosphorus Isotopes; Protein Structure, Secondary; Unilamellar Liposomes | 2010 |
Revealing the lytic mechanism of the antimicrobial peptide gomesin by observing giant unilamellar vesicles.
Topics: Antimicrobial Cationic Peptides; Microscopy, Fluorescence; Models, Theoretical; Phosphatidylcholines; Phosphatidylglycerols; Unilamellar Liposomes | 2010 |
Spectroscopic and thermodynamic evidence for antimicrobial peptide membrane selectivity.
Topics: Amino Acid Sequence; Anti-Infective Agents; Antimicrobial Cationic Peptides; Calorimetry; Circular Dichroism; Liposomes; Phosphatidylcholines; Phosphatidylglycerols; Thermodynamics | 2010 |
Steric confinement of proteins on lipid membranes can drive curvature and tubulation.
Topics: Biophysics; Histidine; Models, Chemical; Phosphatidylcholines; Protein Binding; Proteins; Unilamellar Liposomes | 2010 |
Oxidation changes physical properties of phospholipid bilayers: fluorescence spectroscopy and molecular simulations.
Topics: Cell Membrane; Diffusion; Lipid Bilayers; Molecular Dynamics Simulation; Oxidation-Reduction; Phosphatidylcholines; Phospholipid Ethers; Phospholipids; Physical Phenomena; Solvents; Spectrometry, Fluorescence | 2010 |
Microcalorimetric and zeta potential study on binding of drugs on liposomes.
Topics: Algorithms; Alprenolol; Binding Sites; Binding, Competitive; Calorimetry; Entropy; Kinetics; Labetalol; Liposomes; Models, Chemical; Molecular Structure; Pharmaceutical Preparations; Phosphatidylcholines; Phosphatidylglycerols; Propranolol; Tetracaine; Thermodynamics | 2010 |
Liposomes destabilize tRNA during heat stress.
Topics: Cholesterol; Circular Dichroism; Escherichia coli; Heat-Shock Response; Hot Temperature; Liposomes; Nucleic Acid Conformation; Phosphatidylcholines; RNA, Bacterial; RNA, Transfer | 2010 |
Phospholipid composition of membranes directs prions down alternative aggregation pathways.
Topics: Centrifugation, Density Gradient; Lipid Bilayers; Models, Biological; Particle Size; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Prions; Protein Structure, Quaternary; Protein Structure, Secondary; Solutions | 2010 |
Interactions between a voltage sensor and a toxin via multiscale simulations.
Topics: Lipid Bilayers; Models, Molecular; Molecular Dynamics Simulation; Peptides; Phosphatidylcholines; Potassium Channels, Voltage-Gated; Spider Venoms | 2010 |
Solvent-exposed tails as prestalk transition states for membrane fusion at low hydration.
Topics: Kinetics; Lipid Bilayers; Membrane Fusion; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines; Solvents; Thermodynamics | 2010 |
Model studies of membrane disruption by photogenerated oxidative assault.
Topics: Lipid Bilayers; Models, Molecular; Oxidation-Reduction; Oxidative Stress; Phosphatidylcholines; Reactive Oxygen Species; Temperature; Ultraviolet Rays | 2010 |
Effects of glycerol and urea on micellization, membrane partitioning and solubilization by a non-ionic surfactant.
Topics: Calorimetry; Diphenylhexatriene; Fluorescent Dyes; Glycerol; Liposomes; Micelles; Phosphatidylcholines; Polyethylene Glycols; Solubility; Spectrometry, Fluorescence; Surface-Active Agents; Urea | 2010 |
A closer look at the structure of sterically stabilized liposomes: a small-angle X-ray scattering study.
Topics: Liposomes; Phosphatidylcholines; Polyethylene Glycols; Scattering, Small Angle; X-Ray Diffraction | 2010 |
Coarse grained simulations of local anesthetics encapsulated into a liposome.
Topics: Anesthetics, Local; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Liposomes; Molecular Dynamics Simulation; Phosphatidylcholines; Prilocaine; Static Electricity | 2010 |
Modulation of density and orientation of amphiphilic DNA on phospholipid membranes. II. Vesicles.
Topics: Cholesterol; DNA; Lipid Bilayers; Oligonucleotides; Phosphatidylcholines; Phospholipids | 2010 |
Modulation of density and orientation of amphiphilic DNA anchored to phospholipid membranes. I. Supported lipid bilayers.
Topics: Cholesterol; DNA; Lipid Bilayers; Oligonucleotides; Phosphatidylcholines; Quartz | 2010 |
Electrically addressable, biologically relevant surface-supported bilayers.
Topics: Cholesterol; Electricity; Lipid Bilayers; Membrane Proteins; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Reproducibility of Results; Silicon; Surface Properties | 2010 |
Diffusion as a probe of the heterogeneity of antimicrobial peptide-membrane interactions.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Antimicrobial Cationic Peptides; Cell Membrane Permeability; Diffusion; Intercellular Signaling Peptides and Proteins; Lipid Bilayers; Magainins; Molecular Probes; Organotechnetium Compounds; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Spectrometry, Fluorescence; Unilamellar Liposomes; Xenopus Proteins | 2010 |
On the ability of PAMAM dendrimers and dendrimer/DNA aggregates to penetrate POPC model biomembranes.
Topics: Dendrimers; DNA; Lipid Bilayers; Models, Molecular; Phosphatidylcholines | 2010 |
Role of glycolipids in lipid rafts: a view through atomistic molecular dynamics simulations with galactosylceramide.
Topics: Cholesterol; Galactosylceramides; Hydrogen Bonding; Lipid Bilayers; Membrane Microdomains; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines; Sphingomyelins | 2010 |
Update of the CHARMM all-atom additive force field for lipids: validation on six lipid types.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Dimyristoylphosphatidylcholine; Lipid Bilayers; Lipids; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Quantum Theory; Thermodynamics; X-Ray Diffraction | 2010 |
Reversible liposome association induced by LAH4: a peptide with potent antimicrobial and nucleic acid transfection activities.
Topics: Antimicrobial Cationic Peptides; Circular Dichroism; Light; Lipid Bilayers; Liposomes; Peptides; Phosphatidylcholines; Phosphatidylserines; Protein Structure, Secondary; Scattering, Radiation; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis | 2010 |
Thermodynamic and kinetic stability of discoidal high-density lipoprotein formation from phosphatidylcholine/apolipoprotein A-I mixture.
Topics: Apolipoprotein A-I; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Circular Dichroism; Kinetics; Lipoproteins, HDL; Phosphatidylcholines; Protein Conformation; Protein Stability; Sodium Cholate; Spectrometry, Fluorescence; Thermodynamics | 2010 |
Nanodomain formation in lipid membranes probed by time-resolved fluorescence.
Topics: Diglycerides; Liposomes; Membrane Lipids; Models, Theoretical; Molecular Structure; Phosphatidylcholines; Pyrenes; Spectrometry, Fluorescence | 2010 |
Structural characterization of two pore-forming peptides: consequences of introducing a C-terminal tryptophan.
Topics: Anions; Chloride Channels; Chlorides; Computational Biology; Databases, Protein; Drug Discovery; Electrochemical Techniques; Ion Transport; Kinetics; Lipid Bilayers; Micelles; Models, Molecular; Molecular Dynamics Simulation; Molecular Mimicry; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphatidylcholines; Protein Conformation; Receptors, Glycine; Tryptophan | 2010 |
Water replacement hypothesis in atomic details: effect of trehalose on the structure of single dehydrated POPC bilayers.
Topics: Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Trehalose; Water | 2010 |
Effects of emulsifier concentration, composition, and order of addition in squalene-phosphatidylcholine oil-in-water emulsions.
Topics: Adjuvants, Immunologic; Biological Assay; Drug Delivery Systems; Emulsifying Agents; Emulsions; Humans; Oils; Particle Size; Phosphatidylcholines; Reproducibility of Results; Squalene; Viscosity; Water | 2011 |
Peptide partitioning properties from direct insertion studies.
Topics: Cell Membrane; Lipid Bilayers; Molecular Dynamics Simulation; Peptides; Phosphatidylcholines; Probability; Protein Conformation; Thermodynamics | 2010 |
Lipid domains in bicelles containing unsaturated lipids and cholesterol.
Topics: Cholesterol; Diffusion; Dimyristoylphosphatidylcholine; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phospholipid Ethers; Temperature | 2010 |
Atomic-resolution simulations predict a transition state for vesicle fusion defined by contact of a few lipid tails.
Topics: Computer Simulation; Hemagglutinins, Viral; Hydrophobic and Hydrophilic Interactions; Membrane Fusion; Models, Molecular; Orthomyxoviridae; Phosphatidylcholines; Phosphatidylethanolamines; Transport Vesicles; Water | 2010 |
Crystalline domain structure and cholesterol crystal nucleation in single hydrated DPPC:cholesterol:POPC bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Crystallography, X-Ray; Lipid Bilayers; Phosphatidylcholines; Water | 2010 |
Protegrin-1 orientation and physicochemical properties in membrane bilayers studied by potential of mean force calculations.
Topics: Antimicrobial Cationic Peptides; Chemical Phenomena; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Reference Standards | 2010 |
Selective toxicity of antimicrobial peptide S-thanatin on bacteria.
Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Cell Membrane; Cell Membrane Permeability; Cholesterol; Escherichia coli; Hemolysis; Hemolytic Agents; Humans; Kinetics; Membrane Potentials; Micelles; Osmolar Concentration; Oxidative Phosphorylation; Phosphatidylcholines; Protein Structure, Secondary; Solvents; Staphylococcus aureus; Trifluoroethanol; Uncoupling Agents; Unilamellar Liposomes | 2010 |
Small-angle orientational motions of spin-labeled lipids in cholesterol-containing bilayers studied at low temperatures by electron spin echo spectroscopy.
Topics: Cholesterol; Cold Temperature; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Phosphatidylcholines; Spin Labels | 2010 |
Expression and recovery of biologically active recombinant Apolipoprotein AI(Milano) from transgenic safflower (Carthamus tinctorius) seeds.
Topics: Animals; Apolipoprotein A-I; Carthamus tinctorius; Cholesterol; Lipid Metabolism; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Plants, Genetically Modified; Recombinant Fusion Proteins; Seeds | 2011 |
Sphingomyelin analogs with branched N-acyl chains: the position of branching dramatically affects acyl chain order and sterol interactions in bilayer membranes.
Topics: Calorimetry, Differential Scanning; Cholesterol; Lipid Bilayers; Phosphatidylcholines; Phospholipids; Sphingomyelins; Sterols; Temperature | 2010 |
Distribution and dynamics of rat basophilic leukemia immunoglobulin E receptors (FcepsilonRI) on planar ligand-presenting surfaces.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Cell Line, Tumor; Cell Membrane; Fluorescence; Leukemia, Basophilic, Acute; Ligands; Phosphatidylcholines; Rats; Receptors, IgE; Time Factors | 2010 |
Implication of sphingomyelin/ceramide molar ratio on the biological activity of sphingomyelinase.
Topics: Bacillus cereus; Cell Membrane; Ceramides; Hydrolysis; Phosphatidylcholines; Scattering, Small Angle; Sphingomyelin Phosphodiesterase; Sphingomyelins; X-Ray Diffraction | 2010 |
Transmembrane peptides influence the affinity of sterols for phospholipid bilayers.
Topics: Anisotropy; beta-Cyclodextrins; Cholestenes; Dimyristoylphosphatidylcholine; Diphenylhexatriene; Lipid Bilayers; Peptides; Phosphatidylcholines; Phospholipids | 2010 |
Cholesterol in bilayers with PUFA chains: doping with DMPC or POPC results in sterol reorientation and membrane-domain formation.
Topics: Cell Membrane; Cholesterol; Dimyristoylphosphatidylcholine; Fatty Acids, Unsaturated; Lipid Bilayers; Models, Molecular; Neutron Diffraction; Phosphatidylcholines; Sterols | 2010 |
Calix[4]pyrrole-based anion transporters with tuneable transport properties.
Topics: Anions; Calixarenes; Calorimetry; Crystallography, X-Ray; Ion Transport; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Molecular; Phosphatidylcholines; Porphyrins; Titrimetry | 2010 |
A systematically coarse-grained solvent-free model for quantitative phospholipid bilayer simulations.
Topics: Diffusion; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phospholipids; Solvents | 2010 |
Using microcantilevers to study the interactions of lipid bilayers with solid surfaces.
Topics: Adsorption; Cell Membrane; Cholesterol; Lipid Bilayers; Phosphatidylcholines; Silicon Dioxide; Static Electricity; Surface Properties; Thermodynamics; Unilamellar Liposomes | 2010 |
Partial area of cholesterol in monounsaturated diacylphosphatidylcholine bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Lipid Bilayers; Neutron Diffraction; Phosphatidylcholines; Scattering, Small Angle; Unilamellar Liposomes | 2010 |
Small-amplitude backbone motions of the spin-labeled lipopeptide trichogin GA IV in a lipid membrane as revealed by electron spin echo.
Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Lipopeptides; Motion; Phosphatidylcholines; Spin Labels | 2010 |
Behavior of 1,2-dioleoyl-sn-glycero-3-phosphocholine at the surface of 3-hydroxypropionitrile near the critical micelle concentration.
Topics: Micelles; Nitriles; Phosphatidylcholines; Surface-Active Agents | 2010 |
Assembly of the m2 tetramer is strongly modulated by lipid chain length.
Topics: Amino Acid Sequence; Cell Membrane; Fluorescence Resonance Energy Transfer; Influenza A virus; Lipid Bilayers; Molecular Sequence Data; Phosphatidylcholines; Protein Conformation; Protein Multimerization; Viral Matrix Proteins | 2010 |
Membrane lipid composition differentially modulates the function of human plasma platelet activating factor-acetylhydrolase.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Blood Platelets; Cholesterol; Enzyme Activation; Humans; Lipoproteins; Phosphatidylcholines; Phospholipases A2 | 2011 |
Effect of membrane structure on the action of polyenes II: nystatin activity along the phase diagram of ergosterol- and cholesterol-containing POPC membranes.
Topics: Cholesterol; Ergosterol; Membranes; Nystatin; Phosphatidylcholines; Polyenes; Unilamellar Liposomes | 2010 |
Effect of membrane structure on the action of polyenes: I. Nystatin action in cholesterol- and ergosterol-containing membranes.
Topics: Cholesterol; Ergosterol; Membranes; Nystatin; Phosphatidylcholines; Polyenes; Unilamellar Liposomes | 2010 |
The intermembrane ceramide transport catalyzed by CERT is sensitive to the lipid environment.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Catalysis; Ceramides; Cholesterol; Escherichia coli; Fluorescence Polarization; Humans; Lipid Bilayers; Lipids; Mutation; Phosphates; Phosphatidylcholines; Phosphatidylinositols; Phospholipids; Protein Serine-Threonine Kinases; Sphingomyelins | 2011 |
Kinetics of electron transfer between NADPH-cytochrome P450 reductase and cytochrome P450 3A4.
Topics: Biocatalysis; Cytochrome P-450 CYP3A; Electron Transport; Humans; Hydroxylation; Hydroxytestosterones; Kinetics; Liposomes; Models, Molecular; NADP; NADPH-Ferrihemoprotein Reductase; Phosphatidic Acids; Phosphatidylcholines; Protein Binding; Recombinant Proteins; Testosterone | 2010 |
Reaction of a phospholipid monolayer with gas-phase ozone at the air-water interface: measurement of surface excess and surface pressure in real time.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Air; Microscopy; Neutron Diffraction; Oxygen; Ozone; Phosphatidylcholines; Pressure; Surface Properties; Time Factors; Water | 2010 |
Development of fluorophore dynamics imaging as a probe for lipid domains in model vesicles and cell membranes.
Topics: Cell Membrane; Diphenylhexatriene; Fluorescent Dyes; Lipid Bilayers; Membrane Microdomains; Microscopy, Fluorescence; Phosphatidylcholines; Phosphatidylethanolamines; Photons; Unilamellar Liposomes | 2011 |
Pores formed by Baxα5 relax to a smaller size and keep at equilibrium.
Topics: Amino Acid Sequence; Animals; bcl-2-Associated X Protein; Biophysical Phenomena; Cardiolipins; Cattle; Fluorescent Dyes; Humans; In Vitro Techniques; Kinetics; Macromolecular Substances; Microscopy, Confocal; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Thermodynamics; Unilamellar Liposomes | 2010 |
pH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation.
Topics: Actins; Amanita; Cell Line, Tumor; Cell Proliferation; Humans; Hydrogen-Ion Concentration; Membrane Proteins; Molecular Structure; Mycotoxins; Neoplasms; Phalloidine; Phosphatidylcholines; Protein Transport | 2010 |
A facile approach for assembling lipid bilayer membranes on template-stripped gold.
Topics: Biomimetics; Disulfides; Gold; Lipid Bilayers; Lipids; Microscopy, Atomic Force; Microscopy, Fluorescence; Models, Chemical; Phosphatidylcholines; Proteins; Sulfhydryl Compounds; Surface Properties | 2010 |
Tools for predicting binding and insertion of CPPs into lipid bilayers.
Topics: Amino Acid Sequence; Cell-Penetrating Peptides; Computational Biology; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Sequence Data; Octanols; Phosphatidylcholines; Protein Binding; Protein Structure, Secondary; Thermodynamics; Water | 2011 |
Behavior of 2,6-bis(decyloxy)naphthalene inside lipid bilayer.
Topics: Lipid Bilayers; Molecular Dynamics Simulation; Naphthalenes; Phosphatidylcholines; Quantum Theory; Spectrometry, Fluorescence | 2010 |
Chain length effect on the binding of amphiphiles to serum albumin and to POPC bilayers.
Topics: Amines; Animals; Azoles; Binding Sites; Cattle; Models, Biological; Nitrobenzenes; Phosphatidylcholines; Protein Binding; Serum Albumin, Bovine; Surface-Active Agents; Thermodynamics; Water | 2010 |
A dual host approach to transmembrane transport of salts.
Topics: Acridines; Calixarenes; Fluorescent Dyes; Lipid Bilayers; Phosphatidylcholines; Porphyrins; Salts; Spectrometry, Fluorescence; Valinomycin | 2011 |
Segregation of negatively charged phospholipids by the polycationic and farnesylated membrane anchor of Kras.
Topics: Cell Membrane; Computer Simulation; Lipid Bilayers; Models, Molecular; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Polyamines; Polyelectrolytes; Prenylation; Protein Structure, Secondary; ras Proteins; Reproducibility of Results; Time Factors | 2010 |
Interactions of alkali metal chlorides with phosphatidylcholine vesicles.
Topics: Calorimetry; Cell Membrane; Chlorides; Liposomes; Metals, Alkali; Phosphatidylcholines; Surface Properties; Thermodynamics | 2010 |
Membrane insertion topology of the central apolipoprotein A-I region. Fluorescence studies using single tryptophan mutants.
Topics: Apolipoprotein A-I; Dimyristoylphosphatidylcholine; Fluorescence Polarization; Humans; Lipid Bilayers; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylcholines; Predictive Value of Tests; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Protein Transport; Repetitive Sequences, Amino Acid; Spectrometry, Fluorescence; Tryptophan | 2011 |
Water-templated transmembrane nanopores from shape-persistent oligocholate macrocycles.
Topics: Cell Membrane; Cholates; Cholesterol; Glucose; Hydrophobic and Hydrophilic Interactions; Macrocyclic Compounds; Models, Molecular; Molecular Conformation; Nanopores; Permeability; Phosphatidylcholines; Phosphatidylglycerols; Unilamellar Liposomes; Water | 2011 |
The importance of bacterial membrane composition in the structure and function of aurein 2.2 and selected variants.
Topics: Anti-Infective Agents; Antimicrobial Cationic Peptides; Cell Membrane; Circular Dichroism; Gram-Positive Bacteria; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols | 2011 |
Membrane docking of the C2 domain from protein kinase Cα as seen by polarized ATR-IR. The role of PIP₂.
Topics: Cell Membrane; Cytosol; Humans; Models, Molecular; Phosphatidylcholines; Phosphatidylserines; Phospholipases A2; Protein Kinase C-alpha; Protein Structure, Tertiary; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared | 2011 |
Morphological changes induced by the action of antimicrobial peptides on supported lipid bilayers.
Topics: Antimicrobial Cationic Peptides; Calcium; Lipid Bilayers; Microscopy, Fluorescence; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Static Electricity | 2011 |
Role of cationic group structure in membrane binding and disruption by amphiphilic copolymers.
Topics: Amines; Anti-Infective Agents; Binding Sites; Cations; Cell Membrane; Drug Delivery Systems; Fluorescent Dyes; Fluorometry; Hydrogen Bonding; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Phosphates; Phosphatidylcholines; Polymers; Quaternary Ammonium Compounds; Surface-Active Agents | 2011 |
Dissimilar interaction of CB1/CB2 with lipid bilayers as revealed by molecular dynamics simulation.
Topics: Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Interaction Domains and Motifs; Protein Structure, Tertiary; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2 | 2011 |
Lipid bilayer molecular dynamics study of lipid-derived agonists of the putative cannabinoid receptor, GPR55.
Topics: Arachidonic Acids; Cannabinoid Receptor Agonists; Endocannabinoids; Hydrogen Bonding; Ligands; Lipid Bilayers; Lysophospholipids; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines; Polyunsaturated Alkamides; Receptor, Cannabinoid, CB1; Receptors, Cannabinoid; Thermodynamics | 2011 |
Coarse-grained molecular dynamics simulations of cobra cytotoxin A3 interactions with a lipid bilayer: penetration of loops into membranes.
Topics: Animals; Cobra Cardiotoxin Proteins; Elapidae; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Structure, Secondary; Thermodynamics | 2011 |
Structure and dynamics of the lipid modifications of a transmembrane α-helical peptide determined by ²H solid-state NMR spectroscopy.
Topics: Cell Membrane; Deuterium; Lipid Bilayers; Magnetic Resonance Spectroscopy; Peptide Fragments; Phosphatidylcholines | 2011 |
Molecular dynamics studies of transportan 10 (tp10) interacting with a POPC lipid bilayer.
Topics: Galanin; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Structure, Secondary; Recombinant Fusion Proteins; Static Electricity; Temperature; Wasp Venoms | 2011 |
Effect of high pressure on fully hydrated DPPC and POPC bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Pressure | 2011 |
DL- and PO-phosphatidylcholines as a promising learning and memory enhancer.
Topics: Aged; Aged, 80 and over; Animals; Cognition Disorders; Disease Models, Animal; Drug Combinations; Female; Humans; Male; Maze Learning; Memory Disorders; Middle Aged; Nootropic Agents; Phosphatidylcholines; Rats; Rats, Wistar; Scopolamine | 2011 |
Spin-label oximetry at Q- and W-band.
Topics: Electron Spin Resonance Spectroscopy; Lipid Bilayers; Lipids; Liposomes; Membranes, Artificial; Microwaves; Nitrogen Oxides; Oximetry; Oxygen; Phosphatidylcholines; Reactive Oxygen Species; Spin Labels; Stearic Acids | 2011 |
Evidence from solid-state NMR for nonhelical conformations in the transmembrane domain of the amyloid precursor protein.
Topics: Amino Acid Sequence; Amyloid beta-Protein Precursor; Animals; Cattle; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Neurons; Phosphatidylcholines; Protein Structure, Secondary; Protein Structure, Tertiary; Temperature | 2011 |
Interaction of zervamicin IIB with lipid bilayers. Molecular dynamics study.
Topics: Lipid Bilayers; Molecular Dynamics Simulation; Molecular Structure; Peptaibols; Phosphatidylcholines; Protein Conformation | 2011 |
25-Hydroxycholesterol increases the availability of cholesterol in phospholipid membranes.
Topics: Biological Availability; Cholesterol; Hydrogen Bonding; Hydroxycholesterols; Lipid Bilayers; Membranes, Artificial; Molecular Dynamics Simulation; Phosphatidylcholines; Phospholipids; Solvents | 2011 |
The presence of membranes or micelles induces structural changes of the myristoylated guanylate-cyclase activating protein-2.
Topics: Calcium-Binding Proteins; Guanylate Cyclase-Activating Proteins; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Micelles; Myristic Acid; Nerve Tissue Proteins; Phosphatidylcholines; Photoreceptor Cells; Protein Binding; Retina; Temperature | 2011 |
Stabilization of liposomes in frozen solutions through control of osmotic flow and internal solution freezing by trehalose.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Cryopreservation; Cryoprotective Agents; Dimyristoylphosphatidylcholine; Fluoresceins; Freeze Drying; Freezing; Light; Liposomes; Osmosis; Particle Size; Phosphatidylcholines; Scattering, Radiation; Technology, Pharmaceutical; Trehalose | 2011 |
"Sticky" and "promiscuous", the yin and yang of apolipoprotein A-I termini in discoidal high-density lipoproteins: a combined computational-experimental approach.
Topics: Amino Acid Sequence; Apolipoprotein A-I; Cholesterol; Computer Simulation; Humans; Lipoproteins, HDL; Membrane Fusion; Molecular Dynamics Simulation; Molecular Sequence Data; Particle Size; Phosphatidylcholines; Protein Structure, Secondary; Protein Structure, Tertiary; Temperature | 2011 |
Promotion of vesicular stomatitis virus fusion by the endosome-specific phospholipid bis(monoacylglycero)phosphate (BMP).
Topics: Animals; Cell Line; Cholesterol; Endosomes; Hydrogen-Ion Concentration; Lipids; Liposomes; Lysophospholipids; Membrane Fusion; Membrane Glycoproteins; Monoglycerides; Phosphatidylcholines; Phosphatidylserines; Vesicular stomatitis Indiana virus; Viral Envelope Proteins; Virus Internalization | 2011 |
Small-angle neutron scattering studies of the effects of amphotericin B on phospholipid and phospholipid-sterol membrane structure.
Topics: Amphotericin B; Antifungal Agents; Cell Membrane; Cholesterol; Ergosterol; Humans; Kinetics; Lipid Bilayers; Models, Molecular; Molecular Structure; Mycoses; Neutron Diffraction; Phosphatidylcholines; Phospholipids; Scattering, Small Angle; Sterols; Temperature | 2011 |
Exploring the conformational dynamics and membrane interactions of PorB from C. glutamicum: a multi-scale molecular dynamics simulation study.
Topics: Bacterial Outer Membrane Proteins; Cell Membrane; Corynebacterium glutamicum; Lipid Bilayers; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines; Phospholipids; Porins; Protein Binding; Protein Multimerization; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits | 2011 |
Membrane thickness varies around the circumference of the transmembrane protein BtuB.
Topics: Bacterial Outer Membrane Proteins; Cell Membrane; Escherichia coli; Escherichia coli Proteins; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Membrane Transport Proteins; Models, Molecular; Phosphatidylcholines; Protein Binding; Protein Conformation; Solvents | 2011 |
Permeation of nucleosides through lipid bilayers.
Topics: Lipid Bilayers; Molecular Dynamics Simulation; Nucleosides; Phosphatidylcholines; Ribose; Stereoisomerism | 2011 |
Membrane interface composition drives the structure and the tilt of the single transmembrane helix protein PMP1: MD studies.
Topics: Cell Membrane; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Membrane Proteins; Membranes, Artificial; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylserines; Protein Structure, Secondary; Proteolipids; Proton-Translocating ATPases; Saccharomyces cerevisiae Proteins; Time Factors | 2011 |
Membrane binding of an acyl-lactoferricin B antimicrobial peptide from solid-state NMR experiments and molecular dynamics simulations.
Topics: Acylation; Anisotropy; Anti-Infective Agents; Binding Sites; Escherichia coli; Hydrogen Bonding; Lactoferrin; Membrane Lipids; Membranes, Artificial; Microbial Sensitivity Tests; Molecular Conformation; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Peptide Fragments; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Protein Binding; Staphylococcus aureus; Structure-Activity Relationship | 2011 |
A synergistic approach to anion antiport.
Topics: Bicarbonates; Chlorides; Ion Transport; Lipid Bilayers; Phosphatidylcholines; Unilamellar Liposomes | 2011 |
Self-consistent mean-field model for palmitoyloleoylphosphatidylcholine-palmitoyl sphingomyelin-cholesterol lipid bilayers.
Topics: Anisotropy; Biophysics; Cholesterol; Computer Simulation; Lipid Bilayers; Membrane Fluidity; Models, Chemical; Models, Statistical; Molecular Conformation; Normal Distribution; Phosphatidylcholines; Sphingomyelins | 2011 |
The reproducibility of phospholipid analyses by MALDI-MSMS.
Topics: Ethanolamines; Lithium; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipid Ethers; Phosphorylcholine; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2011 |
Nanodisc-based co-immunoprecipitation for mass spectrometric identification of membrane-interacting proteins.
Topics: Cell Membrane; Escherichia coli Proteins; G(M1) Ganglioside; Immunoprecipitation; Membrane Proteins; Membranes, Artificial; Nanostructures; Phosphatidylcholines; Protein Binding; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Surface Plasmon Resonance | 2011 |
Stable and unstable lipid domains in ceramide-containing membranes.
Topics: Amides; Calorimetry, Differential Scanning; Ceramides; Electron Spin Resonance Spectroscopy; Membranes, Artificial; Phase Transition; Phosphatidylcholines; Spectroscopy, Fourier Transform Infrared; Sphingomyelins; Temperature; Vibration; X-Ray Diffraction | 2011 |
Lipogels: single-lipid-bilayer-enclosed hydrogel spheres.
Topics: Acrylamides; Acrylates; Acrylic Resins; Drug Delivery Systems; Fluorescent Dyes; Freezing; Hydrogels; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Microspheres; Phase Transition; Phosphatidylcholines; Polymers; Spectrometry, Fluorescence; Temperature | 2011 |
Snake cytotoxins bind to membranes via interactions with phosphatidylserine head groups of lipids.
Topics: Animals; Carbon; Cattle; Computer Simulation; Cytotoxins; Fluoresceins; Lipids; Liposomes; Models, Molecular; Models, Statistical; Monte Carlo Method; Phosphatidylcholines; Phosphatidylserines; Protein Structure, Tertiary; Snakes; Sulfoglycosphingolipids; Thermodynamics; Water | 2011 |
Comparative model studies of gastric toxicity of nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Membrane; Cholesterol; Gastric Mucosa; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines; Stomach; Water | 2011 |
Probing insertion and solubilization effects of lysolipids on supported lipid bilayers using microcantilevers.
Topics: Adsorption; Electrochemical Techniques; Lipid Bilayers; Micelles; Phosphatidylcholines; Phospholipids; Silicon Dioxide; Surface-Active Agents; Thermodynamics | 2011 |
Use of simple kinetic and reaction-order measurements for the evaluation of the mechanism of surfactant-liposome interactions.
Topics: Kinetics; Liposomes; Nephelometry and Turbidimetry; Phosphatidylcholines; Surface-Active Agents | 2011 |
Supported lipid bilayer microarrays created by non-contact printing.
Topics: Diffusion; Lipid Bilayers; Microarray Analysis; Phosphatidylcholines; Water | 2011 |
Formation of supported lipid bilayers at surfaces with controlled curvatures: influence of lipid charge.
Topics: Lipid Bilayers; Microscopy, Fluorescence; Nanostructures; Phosphatidylcholines; Quartz Crystal Microbalance Techniques; Surface Properties | 2011 |
Membrane morphology modifications induced by hydroquinones.
Topics: Hydrogen-Ion Concentration; Hydroquinones; Lipid Bilayers; Models, Molecular; Molecular Structure; Particle Size; Phosphatidylcholines; Phosphatidylethanolamines; Stereoisomerism; Surface Properties; Temperature | 2011 |
Influence of the arrangement and secondary structure of melittin peptides on the formation and stability of toroidal pores.
Topics: Biophysics; Computational Biology; Computer Simulation; Lipid Bilayers; Melitten; Micelles; Models, Molecular; Peptides; Phosphatidylcholines; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrophotometry | 2011 |
Thiourea isosteres as anion receptors and transmembrane transporters.
Topics: Anion Transport Proteins; Anions; Antiporters; Benzothiadiazines; Cell Membrane Permeability; Cyclic S-Oxides; Guanidines; Models, Molecular; Phosphatidylcholines; Thiourea; Unilamellar Liposomes; Valinomycin | 2011 |
Fluorescent liposomes for differential interactions with glycosaminoglycans.
Topics: Arylsulfonates; Chondroitin Sulfates; Discriminant Analysis; Fluorescent Dyes; Glycosaminoglycans; Humans; Liposomes; Phosphatidylcholines; Spectrometry, Fluorescence | 2011 |
A combined action of pulmonary surfactant proteins SP-B and SP-C modulates permeability and dynamics of phospholipid membranes.
Topics: Kinetics; Lipid Bilayers; Phosphatidylcholines; Phospholipids; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Protein C; Pulmonary Surfactants; Pyridinium Compounds; Quaternary Ammonium Compounds; Surface Properties | 2011 |
Lipid composition influences the release of Alzheimer's amyloid β-peptide from membranes.
Topics: Alzheimer Disease; Amyloid beta-Peptides; G(M1) Ganglioside; Hydrogen Bonding; Membranes, Artificial; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines | 2011 |
Multitude of morphological dynamics of giant multilamellar vesicles in regulated nonequilibrium environments.
Topics: Liposomes; Microscopy, Phase-Contrast; Phosphatidylcholines | 2011 |
Surface chemistry of lipid raft and amyloid Aβ (1-40) Langmuir monolayer.
Topics: Adsorption; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cattle; Chemistry, Physical; Cholesterol; Humans; Hydrogen-Ion Concentration; Liposomes; Membrane Microdomains; Peptide Fragments; Phosphatidylcholines; Phosphatidylglycerols; Plaque, Amyloid; Protein Structure, Secondary; Spectrum Analysis; Sphingolipids; Static Electricity; Surface Properties | 2011 |
Automated tracking and analysis of phospholipid vesicle contours in phase contrast microscopy images.
Topics: Algorithms; Cholesterol; Elasticity; Image Processing, Computer-Assisted; Microscopy, Phase-Contrast; Phosphatidylcholines; Phospholipids; Video Recording | 2011 |
Thermodynamic profiling of peptide membrane interactions by isothermal titration calorimetry: a search for pores and micelles.
Topics: Calorimetry; Cryoelectron Microscopy; Intercellular Signaling Peptides and Proteins; Membranes, Artificial; Micelles; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Porosity; Thermodynamics; Titrimetry | 2011 |
Chain-length dependence of insertion, desorption, and translocation of a homologous series of 7-nitrobenz-2-oxa-1,3-diazol-4-yl-labeled aliphatic amines in membranes.
Topics: Amines; Azoles; Fluorescent Dyes; Lipid Bilayers; Nitrobenzenes; Phase Transition; Phosphatidylcholines; Serum Albumin; Temperature; Thermodynamics | 2011 |
The oxysterol 3β-hydroxy-5-oxo-5,6-secocholestan-6-al changes the phase behavior and structure of phosphatidylethanolamine-phosphatidylcholine mixtures.
Topics: Calorimetry, Differential Scanning; Cholesterol; Phosphatidylcholines; Phosphatidylethanolamines; Scattering, Small Angle; X-Ray Diffraction | 2011 |
Control of a nanoscopic-to-macroscopic transition: modulated phases in four-component DSPC/DOPC/POPC/Chol giant unilamellar vesicles.
Topics: Cholesterol; Microscopy, Fluorescence; Nanoparticles; Phase Transition; Phosphatidylcholines; Temperature; Unilamellar Liposomes | 2011 |
C-terminus of apolipoprotein A-I removes phospholipids from a triolein/phospholipids/water interface, but the N-terminus does not: a possible mechanism for nascent HDL assembly.
Topics: Adsorption; Apolipoprotein A-I; High-Density Lipoproteins, Pre-beta; Models, Molecular; Peptides; Phosphatidylcholines; Phospholipids; Structure-Activity Relationship; Temperature; Triolein; Water | 2011 |
Noninvasive neutron scattering measurements reveal slower cholesterol transport in model lipid membranes.
Topics: Biological Transport; Cholesterol; Diffusion; Half-Life; Lipid Bilayers; Models, Biological; Neutron Diffraction; Phosphatidylcholines; Scattering, Small Angle | 2011 |
Reluctance to membrane binding enables accessibility of the synaptobrevin SNARE motif for SNARE complex formation.
Topics: Amino Acid Motifs; Animals; Binding Sites; Electrophoresis, Polyacrylamide Gel; Humans; Lipid Bilayers; Liposomes; Magnetic Resonance Spectroscopy; Nanostructures; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Rats; Recombinant Proteins; SNARE Proteins; Synaptosomal-Associated Protein 25; Syntaxin 1; Vesicle-Associated Membrane Protein 2 | 2011 |
Cytoskeletal-like supramolecular assembly and nanoparticle-based motors in a model protocell.
Topics: Amino Acids; Artificial Cells; Cytoskeleton; Dimyristoylphosphatidylcholine; Enzymes; Hydrogels; Hydrogen Peroxide; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Phosphatidylcholines; Platinum; Temperature | 2011 |
Characterization of cationic liposomes. Influence of the bilayer composition on the kinetics of the liposome breakdown.
Topics: Cations; Electron Spin Resonance Spectroscopy; Kinetics; Lipid Bilayers; Liposomes; Molecular Dynamics Simulation; Nephelometry and Turbidimetry; Octoxynol; Phase Transition; Phosphatidylcholines; Polyethylene Glycols; Quaternary Ammonium Compounds; Transition Temperature | 2011 |
New insight into the mechanism of action of wasp mastoparan peptides: lytic activity and clustering observed with giant vesicles.
Topics: Intercellular Signaling Peptides and Proteins; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Sodium Chloride; Surface Properties; Wasp Venoms | 2011 |
Mechanistic insights into the translocation of full length HIV-1 Tat across lipid membranes.
Topics: Microscopy, Confocal; Microscopy, Fluorescence; Phosphatidylcholines; Protein Transport; tat Gene Products, Human Immunodeficiency Virus; Unilamellar Liposomes | 2011 |
Using spin-label electron paramagnetic resonance (EPR) to discriminate and characterize the cholesterol bilayer domain.
Topics: Biological Transport; Cholesterol; Electron Spin Resonance Spectroscopy; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Oxygen; Phosphatidylcholines; Spin Labels; Temperature | 2011 |
Permeation through the cell membrane of a boron-based β-lactamase inhibitor.
Topics: Bacterial Proteins; beta-Lactam Resistance; beta-Lactamase Inhibitors; Boronic Acids; Cell Membrane; Cell Membrane Permeability; Computer Simulation; Drug Design; Electrophysiology; Enzyme Inhibitors; Gram-Negative Bacteria; Kinetics; Lipid Bilayers; Molecular Structure; Phosphatidylcholines; Thiophenes | 2011 |
Validating affinities for ion-lipid association from simulation against experiment.
Topics: Calorimetry; Hydrogen-Ion Concentration; Ions; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Potassium; Sodium | 2011 |
Molecular dynamics simulations of T-20 HIV fusion inhibitor interacting with model membranes.
Topics: Cholesterol; Enfuvirtide; HIV; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Peptide Fragments; Phosphatidylcholines | 2011 |
Heterotrimeric G protein beta1gamma2 subunits change orientation upon complex formation with G protein-coupled receptor kinase 2 (GRK2) on a model membrane.
Topics: G-Protein-Coupled Receptor Kinase 2; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Lipid Bilayers; Membranes, Artificial; Models, Molecular; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Conformation; Spectrum Analysis; Vibration | 2011 |
Resonance-mode electrochemical impedance measurements of silicon dioxide supported lipid bilayer formation and ion channel mediated charge transport.
Topics: Dielectric Spectroscopy; Gramicidin; Ion Channels; Ion Transport; Lipid Bilayers; Phosphatidylcholines; Silicon Dioxide | 2011 |
A modular molecular photovoltaic system based on phospholipid/alkanethiol hybrid bilayers: photocurrent generation and modulation.
Topics: Alkanes; Coordination Complexes; Fullerenes; Membranes, Artificial; Organometallic Compounds; Phosphatidylcholines; Photochemistry; Sulfhydryl Compounds | 2011 |
Triplet excitons of carotenoids formed by singlet fission in a membrane.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Circular Dichroism; Electrons; Energy Transfer; Gels; Kinetics; Light-Harvesting Protein Complexes; Lipid Bilayers; Phosphatidylcholines; Singlet Oxygen; Spectrum Analysis, Raman; Xanthophylls; Zeaxanthins | 2011 |
Self-reproduction of supramolecular giant vesicles combined with the amplification of encapsulated DNA.
Topics: Artificial Cells; DNA; Lipid Bilayers; Origin of Life; Phosphatidylcholines; Phosphatidylglycerols; Polymerase Chain Reaction; Rhodamines | 2011 |
Cholesterol driven alteration of the conformation and dynamics of phospholamban in model membranes.
Topics: Amino Acid Sequence; Animals; Calcium-Binding Proteins; Cholesterol; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Sequence Data; Phosphatidylcholines; Protein Conformation; Rabbits | 2011 |
Metabolically stabilized derivatives of phosphatidylinositol 4-phosphate: synthesis and applications.
Topics: Adaptor Proteins, Signal Transducing; Binding Sites; Inositol Phosphates; Ligands; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Probes; Molecular Structure; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositol Phosphates; Phosphatidylinositols; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Signal Transduction | 2011 |
Advantages of statistical analysis of giant vesicle flickering for bending elasticity measurements.
Topics: Data Interpretation, Statistical; Elasticity; Fluorescent Dyes; Lipid Bilayers; Lipid Peroxidation; Phosphatidylcholines; Temperature; Unilamellar Liposomes | 2011 |
The effect of the placement and total charge of the basic amino acid clusters on antibacterial organism selectivity and potency.
Topics: Amino Acid Sequence; Amino Acids, Basic; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Calorimetry; Circular Dichroism; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Structure-Activity Relationship | 2011 |
Kinetics of demetallation of a zinc-salophen complex into liposomes.
Topics: Kinetics; Octoxynol; Phosphatidylcholines; Salicylates; Unilamellar Liposomes; Zinc | 2012 |
Material properties of matrix lipids determine the conformation and intermolecular reactivity of diacetylenic phosphatidylcholine in the lipid bilayer.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Chemistry, Physical; Chromatography, Liquid; Lipid Bilayers; Microscopy, Fluorescence; Molecular Conformation; Molecular Dynamics Simulation; Phase Transition; Phosphatidylcholines; Phosphatidylethanolamines; Photochemical Processes; Polymerization; Rhodamines; Tandem Mass Spectrometry; Ultraviolet Rays | 2011 |
Saturation with cholesterol increases vertical order and smoothes the surface of the phosphatidylcholine bilayer: a molecular simulation study.
Topics: Cholesterol; Lipid Bilayers; Models, Chemical; Phosphatidylcholines | 2012 |
Protonation states of important acidic residues in the central Ca²⁺ ion binding sites of the Ca²⁺-ATPase: a molecular modeling study.
Topics: Amino Acids, Acidic; Animals; Aspartic Acid; Binding Sites; Calcium; Chemical Phenomena; Databases, Protein; Enzyme Stability; Glutamic Acid; Kinetics; Lipid Bilayers; Membrane Fluidity; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines; Potassium; Protein Conformation; Protons; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2011 |
Reconstitution of KCNE1 into lipid bilayers: comparing the structural, dynamic, and activity differences in micelle and vesicle environments.
Topics: Animals; Cell Membrane; Circular Dichroism; Electron Spin Resonance Spectroscopy; Humans; Lipid Bilayers; Liposomes; Micelles; Microinjections; Mutagenesis, Site-Directed; Mutant Proteins; Oocytes; Phosphatidylcholines; Phosphatidylglycerols; Potassium Channels, Voltage-Gated; Protein Stability; Protein Structure, Secondary; Recombinant Proteins; Xenopus laevis | 2011 |
Measurement of lipid nanodomain (raft) formation and size in sphingomyelin/POPC/cholesterol vesicles shows TX-100 and transmembrane helices increase domain size by coalescing preexisting nanodomains but do not induce domain formation.
Topics: Animals; Chickens; Cholesterol; Diphenylhexatriene; Fluorescence; Fluorescence Resonance Energy Transfer; Membrane Microdomains; Nanostructures; Octoxynol; Particle Size; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Sphingomyelins; Sus scrofa; Temperature; Unilamellar Liposomes | 2011 |
Membrane-proximal external HIV-1 gp41 motif adapted for destabilizing the highly rigid viral envelope.
Topics: Amino Acid Motifs; Amino Acid Sequence; Capsid; Cell Membrane; Cholesterol; HIV Envelope Protein gp41; HIV-1; Membranes, Artificial; Models, Molecular; Molecular Sequence Data; Peptides; Phosphatidylcholines; Structure-Activity Relationship; X-Ray Diffraction | 2011 |
Anti-angiogenic therapy via cationic liposome-mediated systemic siRNA delivery.
Topics: Air Sacs; Animals; Argonaute Proteins; Carcinoma, Lewis Lung; Cations; Cell Cycle Checkpoints; Cell Proliferation; Cholesterol; Ethanolamines; Genetic Therapy; Lipids; Liposomes; Male; Mice; Myristates; Neovascularization, Pathologic; Neovascularization, Physiologic; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; RNA Interference; RNA, Small Interfering; Time Factors; Transfection; Tumor Burden | 2012 |
Thermal stabilization of formaldehyde dehydrogenase by encapsulation in liposomes with nicotinamide adenine dinucleotide.
Topics: Aldehyde Oxidoreductases; Bacterial Proteins; Bioreactors; Carbon Dioxide; Enzyme Stability; Enzymes, Immobilized; Hydrogen-Ion Concentration; Kinetics; Liposomes; NAD; Phosphatidylcholines; Pseudomonas; Thermodynamics | 2011 |
Destabilization of lipid membranes by a peptide derived from glycoprotein gp36 of feline immunodeficiency virus: a combined molecular dynamics/experimental study.
Topics: Circular Dichroism; Electron Spin Resonance Spectroscopy; Glycoproteins; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Immunodeficiency Virus, Feline; Lipid Bilayers; Molecular Dynamics Simulation; Oligopeptides; Phosphatidylcholines; Spectrometry, Fluorescence | 2012 |
Head-to-tail interaction between amphotericin B and ergosterol occurs in hydrated phospholipid membrane.
Topics: Amphotericin B; Antifungal Agents; Carbon Isotopes; Cell Membrane; Deuterium Exchange Measurement; Ergosterol; Lipid Bilayers; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phospholipids; Phosphorus Isotopes; Saccharomyces cerevisiae; Water | 2012 |
Complexes of nucleolipid liposomes with single-stranded and double-stranded nucleic acids.
Topics: Adenosine; Calcium; DNA; Glycerophospholipids; Liposomes; Molecular Conformation; Phosphatidylcholines | 2012 |
Solid-state NMR analysis of steroidal conformation of 17α- and 17β-estradiol in the absence and presence of lipid environment.
Topics: Anisotropy; Dimyristoylphosphatidylcholine; Estradiol; Humans; Isomerism; Lipids; Magnetic Resonance Spectroscopy; Molecular Conformation; Phosphatidylcholines; Phosphatidylglycerols; X-Ray Diffraction | 2012 |
Structure, dynamics, and hydration of POPC/POPS bilayers suspended in NaCl, KCl, and CsCl solutions.
Topics: Cesium; Chlorides; Lipid Bilayers; Phosphatidylcholines; Phosphatidylserines; Potassium Chloride; Sodium Chloride | 2012 |
Effects of the pore-forming agent nystatin on giant phospholipid vesicles.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Liposomes; Methanol; Nystatin; Phosphatidylcholines; Surface Tension | 2012 |
Thermodynamic measurements of bilayer insertion of a single transmembrane helix chaperoned by fluorinated surfactants.
Topics: Circular Dichroism; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Peptides; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Surface-Active Agents; Thermodynamics | 2012 |
Apolipoprotein A-II-mediated conformational changes of apolipoprotein A-I in discoidal high density lipoproteins.
Topics: Apolipoprotein A-I; Apolipoprotein A-II; Deuterium Exchange Measurement; Humans; Lipoproteins; Lipoproteins, HDL; Phosphatidylcholines; Protein Structure, Secondary | 2012 |
Nonintercalating nanosubstrates create asymmetry between bilayer leaflets.
Topics: Adsorption; Lipid Bilayers; Molecular Dynamics Simulation; Nanostructures; Phosphatidylcholines; Surface Properties | 2012 |
Lipid diffusion within black lipid membranes measured with dual-focus fluorescence correlation spectroscopy.
Topics: Diffusion; Ions; Lipid Bilayers; Lipids; Osmolar Concentration; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Spectrometry, Fluorescence | 2012 |
Membrane models of E. coli containing cyclic moieties in the aliphatic lipid chain.
Topics: Cell Membrane; Cyclopropanes; Escherichia coli K12; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Models, Chemical; Phosphatidylcholines; Phosphatidylethanolamines | 2012 |
Hydration behaviour of POPC/C(12)-Bet mixtures investigated by sorption gravimetry, (31)P NMR spectroscopy and X-ray diffraction.
Topics: Betaine; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Surface-Active Agents; Water; X-Ray Diffraction | 2012 |
The effect of the length and flexibility of the side chain of basic amino acids on the binding of antimicrobial peptides to zwitterionic and anionic membrane model systems.
Topics: Amino Acid Sequence; Amino Acids, Basic; Antimicrobial Cationic Peptides; Circular Dichroism; Liposomes; Micelles; Models, Biological; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Quantitative Structure-Activity Relationship; Spectrometry, Fluorescence | 2012 |
Modulation of the interaction between neurotensin receptor NTS1 and Gq protein by lipid.
Topics: Animals; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Lipid Bilayers; Phosphatidylcholines; Phosphatidylglycerols; Rats; Receptors, G-Protein-Coupled; Receptors, Neurotensin; Signal Transduction | 2012 |
Molecular dynamics simulations of the Ca2+-pump: a structural analysis.
Topics: Calcium-Transporting ATPases; Lipid Bilayers; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Phosphatidylcholines | 2012 |
Structure of saposin A lipoprotein discs.
Topics: Crystallography, X-Ray; Detergents; Lipoproteins; Lipoproteins, HDL; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Structure, Secondary; Saposins; Surface-Active Agents | 2012 |
Measuring peptide translocation into large unilamellar vesicles.
Topics: Dansyl Compounds; Fluorescence Resonance Energy Transfer; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Trypsin; Unilamellar Liposomes | 2012 |
A quantitative analytical method to test for salt effects on giant unilamellar vesicles.
Topics: Emulsions; Metals, Alkali; Models, Biological; Oils; Phosphatidylcholines; Salts; Unilamellar Liposomes | 2011 |
Determining the mechanism of membrane permeabilizing peptides: identification of potent, equilibrium pore-formers.
Topics: Alamethicin; Amphibian Proteins; Antimicrobial Cationic Peptides; Cathelicidins; Cell Membrane; Cell Membrane Permeability; Dose-Response Relationship, Drug; Ionophores; Kinetics; Lipid Bilayers; Melitten; Peptides; Phosphatidylcholines; Pore Forming Cytotoxic Proteins; Unilamellar Liposomes | 2012 |
Sidedness of interfacial arginine residues and anti-atherogenicity of apolipoprotein A-I mimetic peptides.
Topics: Animals; Apolipoprotein A-I; Arginine; Aryldialkylphosphatase; Atherosclerosis; Chemical Phenomena; Cholesterol; Female; Gene Deletion; Guanidine; Humans; Lipoproteins, HDL; Mice; Oxidation-Reduction; Peptidomimetics; Phosphatidylcholines; Protein Structure, Secondary; Protein Unfolding; Reactive Oxygen Species; Unilamellar Liposomes | 2012 |
Molecular photovoltaic system based on fullerenes and carotenoids co-assembled in lipid/alkanethiol hybrid bilayers.
Topics: Carotenoids; Electrochemical Techniques; Fullerenes; Lipid Bilayers; Lutein; Models, Molecular; Phosphatidylcholines; Photochemical Processes; Spectrophotometry | 2012 |
Binding of peptides corresponding to the carboxy-terminal region of human-β-defensins-1-3 with model membranes investigated by isothermal titration calorimetry.
Topics: Adsorption; Bacteria; beta-Defensins; Calorimetry, Indirect; Dihydropyridines; Diphenylhexatriene; Fluorescence Polarization; Humans; Membranes, Artificial; Phosphatidylcholines; Phosphatidylethanolamines | 2012 |
Comparative molecular dynamics simulations of the antimicrobial peptide CM15 in model lipid bilayers.
Topics: Antimicrobial Cationic Peptides; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary | 2012 |
Losartan's affinity to fluid bilayers modulates lipid-cholesterol interactions.
Topics: Cholesterol; Dimyristoylphosphatidylcholine; Lipid Bilayers; Losartan; Membrane Microdomains; Phosphatidylcholines | 2012 |
Membrane interactions of two arginine-rich peptides with different cell internalization capacities.
Topics: Amino Acid Sequence; Arginine; Calorimetry; Cell Membrane; Cell-Penetrating Peptides; Dimyristoylphosphatidylcholine; Endocytosis; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Lipids; Micelles; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Transport; Refractometry; Spectroscopy, Fourier Transform Infrared; Unilamellar Liposomes | 2012 |
The photophysics of a Rhodamine head labeled phospholipid in the identification and characterization of membrane lipid phases.
Topics: Absorption; Cholesterol; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rhodamines; Spectrometry, Fluorescence; Staining and Labeling | 2012 |
The innate reactivity of a membrane associated peptide towards lipids: acyl transfer to melittin without enzyme catalysis.
Topics: Amino Acid Sequence; Chromatography, Liquid; Mass Spectrometry; Melitten; Membrane Lipids; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Phospholipids | 2012 |
Immunomodulatory and physical effects of phospholipid composition in vaccine adjuvant emulsions.
Topics: Adjuvants, Immunologic; Animals; Antibodies; Chemistry, Pharmaceutical; Dimyristoylphosphatidylcholine; Drug Stability; Emulsifying Agents; Emulsions; Female; Humans; Immunization; Influenza Vaccines; Injections, Intramuscular; Malaria Vaccines; Mice; Mice, Inbred BALB C; Particle Size; Phosphatidylcholines; Squalene; Technology, Pharmaceutical; Time Factors | 2012 |
Observing a model ion channel gating action in model cell membranes in real time in situ: membrane potential change induced alamethicin orientation change.
Topics: Alamethicin; Animals; Cell Membrane; Hydrogen-Ion Concentration; Ions; Kinetics; Lipid Bilayers; Membrane Potentials; Phosphatidylcholines; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Time Factors; Trichoderma | 2012 |
Similar structures but different mechanisms: Prediction of FABPs-membrane interaction by electrostatic calculation.
Topics: Animals; Cattle; Cell Membrane; Chickens; Fatty Acid-Binding Proteins; Humans; Lipid Bilayers; Mice; Models, Molecular; Osmolar Concentration; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Structure, Tertiary; Rats; Species Specificity; Static Electricity; Thermodynamics | 2012 |
Squaramides as potent transmembrane anion transporters.
Topics: Amides; Anions; Chlorides; Hydrogen Bonding; Ion Transport; Membrane Potentials; Molecular Structure; Phosphatidylcholines | 2012 |
Coupling of the fusion and budding of giant phospholipid vesicles containing macromolecules.
Topics: Artificial Cells; Biological Evolution; Cell Division; Cell Membrane; Dextrans; Liposomes; Membrane Fusion; Membrane Lipids; Models, Biological; Models, Chemical; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Polyethylene Glycols; Unilamellar Liposomes | 2012 |
Interaction of hematoporphyrin with lipid membranes.
Topics: Hematoporphyrins; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Water | 2012 |
Locally resolved membrane binding affinity of the N-terminus of α-synuclein.
Topics: alpha-Synuclein; Cell Membrane; Electron Spin Resonance Spectroscopy; Humans; Lewy Bodies; Membranes, Artificial; Mutation; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids | 2012 |
Formation of GM1 ganglioside clusters on the lipid membrane containing sphingomyeline and cholesterol.
Topics: Amyloid beta-Peptides; Cholesterol; Cluster Analysis; G(M1) Ganglioside; Hydrogen Bonding; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Sphingomyelins | 2012 |
Differential effect of cholesterol and its biosynthetic precursors on membrane dipole potential.
Topics: Cholesterol; Dehydrocholesterols; Desmosterol; Ergosterol; Lipid Bilayers; Membrane Potentials; Phosphatidylcholines; Pyridinium Compounds; Water | 2012 |
Elucidating driving forces for liposome rupture: external perturbations and chemical affinity.
Topics: Gold; Lipid Bilayers; Liposomes; Microscopy, Atomic Force; Phosphatidylcholines; Phosphatidylethanolamines | 2012 |
A molecular dynamics study of the lateral free energy profile of a pair of cholesterol molecules as a function of their distance in phospholipid bilayers.
Topics: Cholesterol; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Thermodynamics | 2012 |
Laurdan generalized polarization fluctuations measures membrane packing micro-heterogeneity in vivo.
Topics: 2-Naphthylamine; Animals; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Erythrocyte Membrane; Erythrocytes; Fluorescence Polarization; Fluorescent Dyes; Laurates; Membrane Lipids; Membrane Microdomains; Models, Biological; Models, Chemical; Phosphatidylcholines; Rabbits; Unilamellar Liposomes | 2012 |
The role of lipophilicity in transmembrane anion transport.
Topics: Anions; Biological Products; Hydrophobic and Hydrophilic Interactions; Ion Transport; Lipid Bilayers; Phosphatidylcholines | 2012 |
A novel approach to the investigation of passive molecular permeation through lipid bilayers from atomistic simulations.
Topics: Cell Membrane; Ethanol; Kinetics; Lipid Bilayers; Molecular Dynamics Simulation; Permeability; Phosphatidylcholines; Thermodynamics | 2012 |
Ubiquinone-10 in gold-immobilized lipid membrane structures acts as a sensor for acetylcholine and other tetraalkylammonium cations.
Topics: Acetylcholine; Biosensing Techniques; Cell Membrane; Electrochemistry; Electrodes; Gold; Lipid Bilayers; Liposomes; Phosphatidylcholines; Quaternary Ammonium Compounds; Ubiquinone | 2012 |
The role of cholesterol on the activity and stability of neurotensin receptor 1.
Topics: Amino Acid Motifs; Biophysics; Cell Membrane; Cholesterol; Cholesterol Esters; Crystallography, X-Ray; Fluorescence Resonance Energy Transfer; Humans; Ligands; Lipid Bilayers; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; Pressure; Protein Binding; Receptors, Adrenergic, beta-2; Receptors, Neurotensin; Time Factors | 2012 |
Interkingdom signaling: integration, conformation, and orientation of N-acyl-L-homoserine lactones in supported lipid bilayers.
Topics: Acyl-Butyrolactones; Deuterium; Kinetics; Lipid Bilayers; Molecular Conformation; Phosphatidylcholines; Phosphatidylglycerols; Quorum Sensing; Silicon Dioxide; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2012 |
Templating CdSe tetrapods at the air/water interface with POPC lipids.
Topics: Cadmium Compounds; Nanoparticles; Particle Size; Phase Transition; Phosphatidylcholines; Pressure; Selenium Compounds | 2012 |
Behavior of 4-hydroxynonenal in phospholipid membranes.
Topics: Aldehydes; Fluorescence; Lipid Bilayers; Membranes, Artificial; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Phosphatidylcholines | 2012 |
Anion-selective transport activities of tetrameric sterol-spermine conjugates.
Topics: Anti-Bacterial Agents; Chlorides; Deoxycholic Acid; Hydrogen-Ion Concentration; Ion Transport; Kinetics; Liposomes; Permeability; Phosphatidylcholines; Spermine; Sterols | 2012 |
Antimicrobial selectivity based on zwitterionic lipids and underlying balance of interactions.
Topics: Algorithms; Antimicrobial Cationic Peptides; Biophysics; Ions; Lipid Bilayers; Lipids; Models, Molecular; Models, Statistical; Molecular Conformation; Peptides; Phosphates; Phosphatidylcholines; Phosphatidylethanolamines; Protein Binding; Static Electricity; Thermodynamics | 2012 |
Graphene oxide and lipid membranes: interactions and nanocomposite structures.
Topics: Graphite; Liposomes; Membranes, Artificial; Models, Molecular; Molecular Structure; Nanocomposites; Oxides; Particle Size; Phosphatidylcholines; Surface Properties | 2012 |
Molecular dynamics simulation of HIV fusion inhibitor T-1249: insights on peptide-lipid interaction.
Topics: Cholesterol; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV-1; Humans; Hydrogen Bonding; Lipid Bilayers; Models, Molecular; Molecular Dynamics Simulation; Peptide Fragments; Phosphatidylcholines; Virus Internalization | 2012 |
Lipid interaction and membrane perturbation of human islet amyloid polypeptide monomer and dimer by molecular dynamics simulations.
Topics: Amino Acid Sequence; Cell Membrane; Humans; Islet Amyloid Polypeptide; Lipid Bilayers; Lipid Metabolism; Molecular Dynamics Simulation; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Protein Multimerization; Protein Structure, Secondary; Solvents; Static Electricity | 2012 |
Phase separation and fluctuations in mixtures of a saturated and an unsaturated phospholipid.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Calorimetry, Differential Scanning; Computer Simulation; Fluorescence Resonance Energy Transfer; Gels; Hot Temperature; Monte Carlo Method; Phase Transition; Phosphatidylcholines; Phospholipids; Unilamellar Liposomes | 2012 |
Electro-optical BLM chips enabling dynamic imaging of ordered lipid domains.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Lipid Bilayers; Membrane Microdomains; Microfluidic Analytical Techniques; Microscopy, Confocal; Phosphatidylcholines; Pressure; Sphingolipids; Unilamellar Liposomes | 2012 |
Fluorescence microscopic characterization of ionic polymer bead-supported phospholipid bilayer membrane systems.
Topics: Dextrans; Fluorescence Recovery After Photobleaching; Fluorescent Dyes; Lipid Bilayers; Membrane Fluidity; Microscopy, Fluorescence; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Polymers; Rhodamines; Spectrometry, Fluorescence; Static Electricity; Unilamellar Liposomes | 2012 |
Modulation of the pHLIP transmembrane helix insertion pathway.
Topics: Amino Acid Sequence; Cell Membrane; Hydrogen-Ion Concentration; Kinetics; Lipid Bilayers; Liposomes; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Protein Structure, Secondary; Protein Unfolding; Temperature; Thermodynamics | 2012 |
Phase diagram of ternary cholesterol/palmitoylsphingomyelin/palmitoyloleoyl-phosphatidylcholine mixtures: spin-label EPR study of lipid-raft formation.
Topics: Cholesterol; Electron Spin Resonance Spectroscopy; Membrane Microdomains; Nonlinear Dynamics; Phosphatidylcholines; Sphingomyelins; Spin Labels | 2012 |
Anticancer peptide SVS-1: efficacy precedes membrane neutralization.
Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Humans; Inhibitory Concentration 50; Membranes, Artificial; Peptides; Phosphatidylcholines; Phosphatidylserines; Static Electricity; Stereoisomerism | 2012 |
The membrane binding kinetics of full-length PKCα is determined by membrane lipid composition.
Topics: Animals; Cell Membrane; Diglycerides; Fluorescence Resonance Energy Transfer; Kinetics; Lipid Bilayers; Membrane Lipids; Models, Molecular; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylserines; Protein Binding; Protein Kinase C-alpha; Protein Structure, Tertiary; Spectrometry, Fluorescence; Swine | 2012 |
Docosahexaenoic and eicosapentaenoic acids segregate differently between raft and nonraft domains.
Topics: Cholesterol; Detergents; Docosahexaenoic Acids; Eicosapentaenoic Acid; Magnetic Resonance Spectroscopy; Membrane Microdomains; Membranes, Artificial; Oleic Acids; Phosphatidylcholines; Sphingomyelins; Temperature | 2012 |
Oxidized phosphatidylcholines promote phase separation of cholesterol-sphingomyelin domains.
Topics: Cholesterol; Microscopy; Oxidation-Reduction; Phase Transition; Phosphatidylcholines; Pressure; Sphingomyelins; Surface Properties; Temperature | 2012 |
Spontaneous formation of two-dimensional and three-dimensional cholesterol crystals in single hydrated lipid bilayers.
Topics: Ceramides; Cholesterol; Crystallization; Fluorescent Antibody Technique; Lipid Bilayers; Microscopy, Atomic Force; Microscopy, Fluorescence; Phosphatidylcholines; Water; X-Ray Diffraction | 2012 |
Binding and reorientation of melittin in a POPC bilayer: computer simulations.
Topics: Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Melitten; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Binding; Protein Conformation; Protein Structure, Secondary | 2012 |
Solute transport on the sub 100 ms scale across the lipid bilayer membrane of individual proteoliposomes.
Topics: Acetic Acid; Aquaporin 5; Biological Transport; Cell Membrane; Cell Membrane Permeability; Fluoresceins; Fluorescent Dyes; Glycerol; Humans; Hydrogen-Ion Concentration; Lipid Bilayers; Microfluidic Analytical Techniques; Osmosis; Phosphatidylcholines; Proteolipids; Time Factors; Water | 2012 |
Computational study of room-temperature ionic liquids interacting with a POPC phospholipid bilayer.
Topics: Ionic Liquids; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Temperature | 2012 |
Transmembrane pore formation by the carboxyl terminus of Bax protein.
Topics: Amino Acid Sequence; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspases; Cytochromes c; Dose-Response Relationship, Drug; Fluoresceins; Humans; Kinetics; Mitochondrial Membranes; Models, Statistical; Molecular Sequence Data; Mutation; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Tertiary; Time Factors | 2013 |
LIPID11: a modular framework for lipid simulations using amber.
Topics: Cholesterol; Inositol; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids | 2012 |
Positively charged supported lipid bilayers as a biomimetic platform for neuronal cell culture.
Topics: Animals; Biomimetics; Cell Adhesion; Cell Membrane; Cells, Cultured; Fatty Acids, Monounsaturated; Lipid Bilayers; Models, Biological; Molecular Structure; Neurons; Phosphatidylcholines; Quaternary Ammonium Compounds; Rats | 2012 |
Lateral diffusion of bilayer lipids measured via (31)P CODEX NMR.
Topics: Cholesterol; Diffusion; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Chemical; Phosphatidylcholines; Phosphatidylglycerols; Unilamellar Liposomes; Viscosity | 2012 |
Phosphatidylinositol 4,5-biphosphate (PIP(2)) lipids regulate the phosphorylation of syntaxin N-terminus by modulating both its position and local structure.
Topics: Amino Acid Sequence; Humans; Molecular Dynamics Simulation; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phosphorylation; Protein Conformation; Protein Isoforms; Qa-SNARE Proteins; Sequence Alignment; SNARE Proteins | 2012 |
Conformational dynamics and membrane interactions of the E. coli outer membrane protein FecA: a molecular dynamics simulation study.
Topics: Biological Transport; Biological Transport, Active; Cell Membrane; Computer Simulation; Diffusion; Escherichia coli; Escherichia coli Proteins; Hydrogen Bonding; Ligands; Lipid Bilayers; Lipopolysaccharides; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Proteins; Receptors, Cell Surface | 2013 |
Chemical and physical requirements for lipid extraction by bovine binder of sperm BSP1.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Cattle; Cell Membrane; Dose-Response Relationship, Drug; Lipids; Liposomes; Lysophosphatidylcholines; Male; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phosphorylcholine; Protein Binding; Seminal Vesicle Secretory Proteins; Sperm Capacitation; Spermatozoa; Temperature | 2013 |
Molecular dynamic simulations of the binary complex of human tissue factor (TF(1-242) ) and factor VIIa (TF(1-242) /FVIIa) on a 4:1 POPC/POPS lipid bilayer.
Topics: Calcium; Catalytic Domain; Cell Membrane; Computer Simulation; Factor VIIa; Humans; Hydrophobic and Hydrophilic Interactions; Ions; Lipid Bilayers; Lipids; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Protein Binding; Thromboplastin | 2012 |
Low-frequency ultrasound-induced transport across non-raft-forming ternary lipid bilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Diffusion; Kinetics; Lipid Bilayers; Liposomes; Phase Transition; Phosphatidylcholines; Ultrasonics | 2012 |
How the amyloid-β peptide and membranes affect each other: an extensive simulation study.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Algorithms; Alzheimer Disease; Amyloid beta-Peptides; Cell Membrane; Computer Simulation; Humans; Hydrogen-Ion Concentration; Ions; Lipid Bilayers; Lipids; Magnetic Resonance Spectroscopy; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary; Temperature; Water | 2013 |
Free energy calculation of permeant-membrane interactions using molecular dynamics simulations.
Topics: Benzene; Cell Membrane; Molecular Dynamics Simulation; Permeability; Phosphatidylcholines; Thermodynamics; Time Factors | 2012 |
Insights into buforin II membrane translocation from molecular dynamics simulations.
Topics: Molecular Dynamics Simulation; Phosphatidylcholines; Proteins | 2012 |
N-Ras forms dimers at POPC membranes.
Topics: Fluorescence Resonance Energy Transfer; Lipid Bilayers; Molecular Dynamics Simulation; Mutation; Phosphatidylcholines; Protein Multimerization; Protein Structure, Quaternary; ras Proteins; Spectroscopy, Fourier Transform Infrared; Surface Properties | 2012 |
Identification of cholesterol binding sites in the serotonin1A receptor.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Cell Membrane; Cholesterol; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Sequence Data; Phosphatidylcholines; Receptor, Serotonin, 5-HT1A; Time Factors | 2012 |
Atomistic simulations of a multicomponent asymmetric lipid bilayer.
Topics: Cholesterol; Lipid Bilayers; Phosphatidylcholines; Sphingomyelins | 2012 |
Membrane docking mode of the C2 domain of PKCε: an infrared spectroscopy and FRET study.
Topics: Adenosine; Calcium; Fluorescence Resonance Energy Transfer; Glycerophospholipids; Humans; Lipid Bilayers; Lipids; Mitochondrial Membranes; Models, Molecular; Models, Statistical; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Binding; Protein Conformation; Protein Kinase C-epsilon; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrophotometry, Infrared | 2013 |
Single vesicle analysis reveals nanoscale membrane curvature selective pore formation in lipid membranes by an antiviral α-helical peptide.
Topics: Antiviral Agents; Biotin; Cell Membrane; Fluoresceins; Kinetics; Lipids; Membrane Lipids; Nanoparticles; Nanotechnology; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Rhodamines; Sensitivity and Specificity; Surface Plasmon Resonance; Surface Properties | 2012 |
Dissociation of membrane-anchored heterotrimeric G-protein induced by G(α) subunit binding to GTP.
Topics: Crystallography, X-Ray; Guanosine Diphosphate; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Kinetics; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Binding; Protein Subunits; Thermodynamics | 2012 |
Glycosaminoglycan-mediated selective changes in the aggregation states, zeta potentials, and intrinsic stability of liposomes.
Topics: Calorimetry, Differential Scanning; Glycosaminoglycans; Heparin; Liposomes; Magnesium; Microscopy, Electron, Transmission; Phosphatidylcholines; Phospholipids | 2012 |
Recombinant expression and solution structure of antimicrobial peptide aurelin from jellyfish Aurelia aurita.
Topics: Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides; Bacteria; Escherichia coli; Micelles; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary; Recombinant Proteins; Scyphozoa; Solutions; Water | 2012 |
Interaction of Piscidin-1 with zwitterionic versus anionic membranes: a comparative molecular dynamics study.
Topics: Animals; Anions; Antimicrobial Cationic Peptides; Cell Membrane; Fish Proteins; Lipid Bilayers; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Conformation; Protein Structure, Tertiary | 2013 |
Anesthetics interacting with lipid rafts.
Topics: Anesthetics; Cholesterol; Lidocaine; Lipid Bilayers; Liposomes; Membrane Microdomains; Phosphatidylcholines; Propofol; Sphingomyelins; Tetracaine | 2013 |
Lipid-coated nanocapillaries for DNA sensing.
Topics: Bacteriophage lambda; Biosensing Techniques; DNA, Viral; Glass; Nanopores; Phosphatidylcholines | 2013 |
Aggregation and dynamics of oligocholate transporters in phospholipid bilayers revealed by solid-state NMR spectroscopy.
Topics: Biological Transport; Biomimetic Materials; Carbon Isotopes; Cholates; Cholesterol; Diffusion; Kinetics; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Transport Proteins; Models, Molecular; Nitrogen Isotopes; Phosphatidylcholines; Phosphatidylglycerols; Polymerization; Water | 2012 |
Cholesterol's interactions with serine phospholipids - a comparison of N-palmitoyl ceramide phosphoserine with dipalmitoyl phosphatidylserine.
Topics: Anisotropy; Biophysics; Ceramides; Cholesterol; Fatty Acids, Unsaturated; Hydrogen; Hydrogen Bonding; Lipid Bilayers; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Phosphoserine; Serine; Spectrometry, Fluorescence; Sphingomyelins; Temperature; Time Factors | 2013 |
Lipid-protein nanodiscs promote in vitro folding of transmembrane domains of multi-helical and multimeric membrane proteins.
Topics: Bacteria; Bacterial Proteins; Bacteriorhodopsins; Cell Membrane; Detergents; Dimerization; Dimyristoylphosphatidylcholine; Lipids; Membrane Proteins; Nanostructures; Nanotechnology; Phosphatidylcholines; Phosphatidylglycerols; Potassium Channels; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Sodium Dodecyl Sulfate; Streptomyces lividans | 2013 |
Structure and dynamics of the two amphipathic arginine-rich peptides RW9 and RL9 in a lipid environment investigated by solid-state NMR and MD simulations.
Topics: Arginine; Biophysics; Calorimetry; Cell-Penetrating Peptides; Lipids; Magnetic Resonance Spectroscopy; Models, Molecular; Models, Statistical; Molecular Conformation; Molecular Dynamics Simulation; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Protein Binding; Water | 2013 |
Effect of glucosylceramide on the biophysical properties of fluid membranes.
Topics: Air; Anisotropy; Biophysics; Biotinylation; Cell Membrane; Gels; Glucosylceramides; Humans; Lipid Bilayers; Lipids; Microscopy, Confocal; Phosphatidylcholines; Spectrometry, Fluorescence; Surface Properties; Temperature; Water | 2013 |
Oligolamellar vesicles for covalent immobilization and stabilization of D-amino acid oxidase.
Topics: Alanine; Animals; Chromatography, Gas; D-Amino-Acid Oxidase; Drug Storage; Enzyme Stability; Enzymes, Immobilized; Flavin-Adenine Dinucleotide; Fluorometry; Hydrogen Peroxide; Kidney; Lipid Bilayers; Liposomes; Membrane Fluidity; Membrane Lipids; Nephelometry and Turbidimetry; Phosphatidylcholines; Protein Denaturation; Swine; Temperature; Unilamellar Liposomes | 2013 |
Importance of the sphingoid base length for the membrane properties of ceramides.
Topics: Calorimetry; Ceramides; Cholesterol; Lipid Bilayers; Molecular Structure; Phosphatidylcholines; Sphingomyelins | 2012 |
Cholesterol and POPC segmental order parameters in lipid membranes: solid state 1H-13C NMR and MD simulation studies.
Topics: Carbon Isotopes; Cholesterol; Hydrogen; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Phosphatidylcholines | 2013 |
Lipid complex of apolipoprotein A-I mimetic peptide 4F is a novel platform for paraoxonase-1 binding and enhancing its activity and stability.
Topics: Amino Acid Sequence; Apolipoprotein A-I; Aryldialkylphosphatase; Enzyme Stability; Humans; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Peptides; Phosphatidylcholines; Protein Binding; Recombinant Proteins | 2013 |
Sensing hydration and behavior of pyrene in POPC and POPC/cholesterol bilayers: a molecular dynamics study.
Topics: Biophysics; Cholesterol; Computer Simulation; Dose-Response Relationship, Drug; Fluorescent Dyes; Lipid Bilayers; Lipids; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines; Pyrenes; Temperature; Water | 2013 |
Imaging ellipsometry of spin-coated membranes: mapping of multilamellar films, hydrated membranes, and fluid domains.
Topics: Chemistry Techniques, Analytical; Particle Size; Phosphatidylcholines; Surface Properties; Water | 2013 |
Membrane interactions of the amphipathic amino terminus of huntingtin.
Topics: Amino Acid Sequence; Cell Membrane; Humans; Huntingtin Protein; Lipid Bilayers; Liposomes; Models, Molecular; Molecular Sequence Data; Nerve Tissue Proteins; Permeability; Phosphatidylcholines; Phosphatidylserines; Protein Structure, Secondary; Protein Structure, Tertiary | 2013 |
Probing microscopic material properties inside simulated membranes through spatially resolved three-dimensional local pressure fields and surface tensions.
Topics: Cell Membrane; Ligand-Gated Ion Channels; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Pressure; Protein Structure, Tertiary; Surface Tension | 2013 |
Hemolytic activity of membrane-active peptides correlates with the thermodynamics of binding to 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine bilayers.
Topics: Animals; Antimicrobial Cationic Peptides; Cell-Penetrating Peptides; Hemolysis; Lipid Bilayers; Phosphatidylcholines; Protein Binding; Sheep; Thermodynamics | 2013 |
Cations as switches of amyloid-mediated membrane disruption mechanisms: calcium and IAPP.
Topics: Amyloid; Animals; Calcium; Cations; Cell Membrane; Coloring Agents; Detergents; Humans; Hydrophobic and Hydrophilic Interactions; Islet Amyloid Polypeptide; Lipid Bilayers; Microscopy, Atomic Force; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Quartz Crystal Microbalance Techniques; Rats | 2013 |
Microfluidic hydrodynamic focusing based synthesis of POPC liposomes for model biological systems.
Topics: Hydrodynamics; Liposomes; Microfluidic Analytical Techniques; Models, Biological; Particle Size; Phosphatidylcholines; Surface Properties | 2013 |
Cholesteryl phosphocholine--a study on its interactions with ceramides and other membrane lipids.
Topics: Ceramides; Membrane Lipids; Molecular Structure; Phosphatidylcholines | 2013 |
Effect of phospholipid composition on discoidal HDL formation.
Topics: Algorithms; Anisotropy; Apolipoprotein A-I; Kinetics; Lipid Bilayers; Lipoproteins, HDL; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Spectrometry, Fluorescence; Sphingomyelins; Temperature | 2013 |
2NH and 3OH are crucial structural requirements in sphingomyelin for sticholysin II binding and pore formation in bilayer membranes.
Topics: Animals; Binding Sites; Calorimetry; Cnidarian Venoms; Computer Simulation; Hydrogen Bonding; Kinetics; Lipid Bilayers; Models, Molecular; Molecular Structure; Phosphatidylcholines; Pore Forming Cytotoxic Proteins; Protein Binding; Protein Structure, Tertiary; Sea Anemones; Sphingomyelins; Surface Plasmon Resonance; Unilamellar Liposomes | 2013 |
The electrical response of bilayers to the bee venom toxin melittin: evidence for transient bilayer permeabilization.
Topics: Animals; Bee Venoms; Cell Membrane Permeability; Cholesterol; Dielectric Spectroscopy; Electromagnetic Phenomena; Lipid Bilayers; Melitten; Membrane Lipids; Permeability; Phosphatidylcholines; Phosphatidylglycerols; Time Factors; Unilamellar Liposomes | 2013 |
Quartz crystal microbalances as tools for probing protein-membrane interactions.
Topics: Adsorption; Annexin A5; Elasticity; Lipid Bilayers; Lipids; Phosphatidylcholines; Protein Binding; Protein Multimerization; Proteins; Quartz Crystal Microbalance Techniques; Silicon Dioxide; Viscosity | 2013 |
A guide to tracking single transmembrane proteins in supported lipid bilayers.
Topics: Biochemistry; Diffusion; Lasers; Lipid Bilayers; Liposomes; Membrane Proteins; Phosphatidylcholines; Receptors, Serotonin, 5-HT3; Staining and Labeling | 2013 |
Combination of COSMOmic and molecular dynamics simulations for the calculation of membrane-water partition coefficients.
Topics: Dimyristoylphosphatidylcholine; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Water | 2013 |
Gas-phase transformation of phosphatidylcholine cations to structurally informative anions via ion/ion chemistry.
Topics: Gases; Ions; Phosphatidylcholines; Tandem Mass Spectrometry | 2013 |
Interaction between the marine sponge cyclic peptide theonellamide A and sterols in lipid bilayers as viewed by surface plasmon resonance and solid-state (2)H nuclear magnetic resonance.
Topics: Animals; Lipid Bilayers; Liposomes; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Phosphatidylcholines; Sterols; Surface Plasmon Resonance; Theonella | 2013 |
Degradation and rearrangement of a lung surfactant lipid at the air-water interface during exposure to the pollutant gas ozone.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Air; Air Pollutants; Neutron Diffraction; Oxidation-Reduction; Ozone; Phosphatidylcholines; Pressure; Pulmonary Surfactant-Associated Proteins; Water | 2013 |
Loop sequence dictates the secondary structure of a human membrane protein hairpin.
Topics: Amino Acid Sequence; Cystic Fibrosis Transmembrane Conductance Regulator; Glycine; Humans; Lipid Bilayers; Micelles; Models, Molecular; Molecular Sequence Data; Mutation; Phosphatidylcholines; Proline; Protein Folding; Protein Structure, Secondary; Sodium Dodecyl Sulfate | 2013 |
Molecular interactions of Alzheimer amyloid-β oligomers with neutral and negatively charged lipid bilayers.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Calcium; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary | 2013 |
Laurdan fluorescence lifetime discriminates cholesterol content from changes in fluidity in living cell membranes.
Topics: 2-Naphthylamine; Animals; Biosensing Techniques; Cell Membrane; Cell Survival; Cholesterol; Epidermal Growth Factor; Fluorescent Dyes; Laurates; Membrane Fluidity; Mice; NIH 3T3 Cells; Phosphatidylcholines; Solutions; Spectrometry, Fluorescence | 2013 |
Validation of depth-dependent fluorescence quenching in membranes by molecular dynamics simulation of tryptophan octyl ester in POPC bilayer.
Topics: Lipid Bilayers; Membrane Proteins; Molecular Dynamics Simulation; Phosphatidylcholines; Spectrometry, Fluorescence; Tryptophan | 2013 |
Cholesterol favors the emergence of a long-range autocorrelated fluctuation pattern in voltage-induced ionic currents through lipid bilayers.
Topics: Animals; Cattle; Cell Membrane; Cerebral Cortex; Cholesterol; Electric Capacitance; Ion Transport; Lipid Bilayers; Phosphatidylcholines; Phosphatidylethanolamines; Temperature | 2013 |
Influence of lipid composition on the structural stability of g-protein coupled receptor.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Alprenolol; Binding Sites; Cholesterol; Epinephrine; G(M1) Ganglioside; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Binding; Protein Stability; Protein Structure, Tertiary; Receptors, Adrenergic, beta-2 | 2013 |
Membrane mimetics induce helix formation and oligomerization of the chloride intracellular channel protein 1 transmembrane domain.
Topics: Amino Acid Sequence; Chloride Channels; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Liposomes; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Protein Conformation; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Trifluoroethanol | 2013 |
Composition, structure and properties of POPC-triolein mixtures. Evidence of triglyceride domains in phospholipid bilayers.
Topics: Electron Spin Resonance Spectroscopy; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Scattering, Small Angle; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Triglycerides; Triolein | 2013 |
A molecular dynamics study of the structural and dynamical properties of putative arsenic substituted lipid bilayers.
Topics: Arsenates; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines | 2013 |
Structural characterization of NETNES glycopeptide from Trypanosoma cruzi.
Topics: Cell Membrane; Glycoproteins; Glycosylation; Glycosylphosphatidylinositols; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines; Protozoan Proteins | 2013 |
Frozen translational and rotational motion of human immunodeficiency virus transacting activator of transcription peptide-modified nanocargo on neutral lipid bilayer.
Topics: Adsorption; Amino Acid Sequence; Gold; HIV; Lipid Bilayers; Metal Nanoparticles; Motion; Nanostructures; Peptide Fragments; Phosphatidylcholines; Rotation; tat Gene Products, Human Immunodeficiency Virus; Thermodynamics | 2013 |
Analytical model and multiscale simulations of Aβ peptide aggregation in lipid membranes: towards a unifying description of conformational transitions, oligomerization and membrane damage.
Topics: Amyloid beta-Peptides; Cell Membrane; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Peptide Fragments; Phosphatidylcholines; Protein Structure, Secondary; Thermodynamics | 2013 |
Behavior of fluorescent cholesterol analogues dehydroergosterol and cholestatrienol in lipid bilayers: a molecular dynamics study.
Topics: Cholestenes; Cholesterol; Ergosterol; Fluorescent Dyes; Lipid Bilayers; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines | 2013 |
α-Synuclein oligomers with broken helical conformation form lipoprotein nanoparticles.
Topics: alpha-Synuclein; Cholesterol; Chromatography, Gel; Cryoelectron Microscopy; Fluorescence Resonance Energy Transfer; Humans; Lipoproteins; Membranes, Artificial; Mitochondrial Membranes; Nanoparticles; Particle Size; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Protein Structure, Quaternary; Protein Structure, Secondary | 2013 |
Molecular dynamics simulations of depth distribution of spin-labeled phospholipids within lipid bilayer.
Topics: Cyclic N-Oxides; Diffusion; Lipid Bilayers; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines; Spin Labels | 2013 |
AβP1-42 incorporation and channel formation in planar lipid membranes: the role of cholesterol and its oxidation products.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Blotting, Western; Cholesterol; Electrophoresis; Humans; Lipid Bilayers; Membrane Lipids; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Phosphatidylcholines | 2013 |
Phospholipid-lactose permease interaction as reported by a head-labeled pyrene phosphatidylethanolamine: a FRET study.
Topics: Escherichia coli; Escherichia coli Proteins; Fluorescence Resonance Energy Transfer; Membrane Transport Proteins; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Pyrenes | 2013 |
Molecular interaction of a new antibacterial polymer with a supported lipid bilayer measured by an in situ label-free optical technique.
Topics: Adsorption; Alkylation; Ammonium Compounds; Anisotropy; Anti-Bacterial Agents; Light; Lipid Bilayers; Models, Chemical; Models, Molecular; Phosphatidylcholines; Polyethyleneimine; Spectrum Analysis | 2013 |
Calmodulin adopts an extended conformation when interacting with L-selectin in membranes.
Topics: Amino Acid Sequence; Calmodulin; Cell Membrane; Humans; L-Selectin; Liposomes; Microfilament Proteins; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Protein Binding; Protein Structure, Tertiary; Water | 2013 |
Changes in helical content or net charge of apolipoprotein C-I alter its affinity for lipid/water interfaces.
Topics: Apolipoprotein C-I; Humans; Phosphatidylcholines; Point Mutation; Protein Structure, Secondary; Surface Properties; Triolein; Water | 2013 |
Interactions of alkylphosphocholines with model membranes-the Langmuir monolayer study.
Topics: Animals; Cell Membrane; Cholesterol; Humans; Neoplasms; Phosphatidylcholines; Phosphorylcholine; Unilamellar Liposomes | 2013 |
Hydroxyl radical oxidation of phospholipid-coated NaCl particles.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Hydroxyl Radical; Kinetics; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Photolysis; Sodium Chloride | 2013 |
Macro- versus microscopic view on the electrokinetics of a water-membrane interface.
Topics: Hydrodynamics; Membranes, Artificial; Molecular Dynamics Simulation; Phosphatidylcholines; Surface Properties; Water | 2013 |
Membrane interaction of disease-related dynorphin A variants.
Topics: Cell Membrane; Circular Dichroism; Diffusion; Dimyristoylphosphatidylcholine; Dynorphins; Humans; Lipid Bilayers; Magnetic Resonance Spectroscopy; Micelles; Mutation; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Phospholipid Ethers; Protein Conformation; Solvents; Thermodynamics; Water | 2013 |
Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Binding Sites; Crystallography, X-Ray; Humans; Lipid Bilayers; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Molecular Sequence Data; Mutation; Nucleotides; Phosphatidylcholines; Phosphatidylethanolamines; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sf9 Cells | 2013 |
A membrane-translocating peptide penetrates into bilayers without significant bilayer perturbations.
Topics: Cell Membrane; Lipid Bilayers; Membrane Proteins; Oligopeptides; Phosphatidylcholines; Protein Structure, Secondary; Protein Transport | 2013 |
Phase diagram of a 4-component lipid mixture: DSPC/DOPC/POPC/chol.
Topics: Cholesterol; Fluorescence Resonance Energy Transfer; Phase Transition; Phosphatidylcholines | 2013 |
Cytotoxic bile acids, but not cytoprotective species, inhibit the ordering effect of cholesterol in model membranes at physiologically active concentrations.
Topics: 4-Chloro-7-nitrobenzofurazan; Cholesterol; Deoxycholic Acid; Diphenylhexatriene; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Lipid Bilayers; Phosphatidylcholines; Phosphatidylethanolamines; Staining and Labeling; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid | 2013 |
Interaction of the antimicrobial peptide gomesin with model membranes: a calorimetric study.
Topics: Antimicrobial Cationic Peptides; Calorimetry; Models, Molecular; Particle Size; Phosphatidylcholines; Phospholipids; Surface Properties | 2013 |
Liposome clusters with shear stress-induced membrane permeability.
Topics: Calcium; Cholesterol; Hydrogen-Ion Concentration; Ions; Liposomes; Permeability; Phosphatidylcholines; Phosphatidylglycerols; Shear Strength | 2013 |
Functionalized 129Xe as a potential biosensor for membrane fluidity.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Biosensing Techniques; Contrast Media; Liposomes; Magnetic Resonance Imaging; Membrane Fluidity; Phosphatidylcholines; Xenon Isotopes | 2013 |
Critical point fluctuations in supported lipid membranes.
Topics: Cell Membrane; Image Processing, Computer-Assisted; Lipid Bilayers; Membrane Fluidity; Membrane Lipids; Membrane Microdomains; Microscopy, Atomic Force; Phosphatidylcholines; Temperature | 2013 |
Elastic properties of polyunsaturated phosphatidylethanolamines influence rhodopsin function.
Topics: Animals; Cattle; Cell Membrane; Light; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylethanolamines; Rhodopsin; X-Ray Diffraction | 2013 |
Effect of repeated apoA-IMilano/POPC infusion on lipids, (apo)lipoproteins, and serum cholesterol efflux capacity in cynomolgus monkeys.
Topics: Animals; Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins E; Biological Transport; Cholesterol; Drug Combinations; Esterification; Female; Lipoproteins, LDL; Lipoproteins, VLDL; Macaca fascicularis; Male; Phosphatidylcholines; Recombinant Fusion Proteins; Time Factors | 2013 |
Membrane bound α-synuclein is fully embedded in the lipid bilayer while segments with higher flexibility remain.
Topics: Acrylamide; alpha-Synuclein; Amino Acid Sequence; Cell Membrane; Humans; Lipid Bilayers; Lipids; Micelles; Molecular Sequence Data; Parkinson Disease; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Structure, Tertiary; Tryptophan | 2013 |
Membrane binding and insertion of a pHLIP peptide studied by all-atom molecular dynamics simulations.
Topics: Amino Acid Sequence; Hydrogen-Ion Concentration; Ions; Lipid Bilayers; Membrane Proteins; Molecular Dynamics Simulation; Molecular Sequence Data; Phosphatidylcholines; Protein Binding; Water | 2013 |
Effect of amphipathic HIV fusion inhibitor peptides on POPC and POPC/cholesterol membrane properties: a molecular simulation study.
Topics: Cholesterol; Enfuvirtide; HIV; HIV Envelope Protein gp41; HIV Fusion Inhibitors; Humans; Hydrogen Bonding; Lipid Bilayers; Molecular Dynamics Simulation; Peptide Fragments; Peptides; Phosphatidylcholines; Protein Binding; Protein Structure, Tertiary | 2013 |
Low-visibility light-intensity laser-triggered release of entrapped calcein from 1,2-bis (tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine liposomes is mediated through a type I photoactivation pathway.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Ascorbic Acid; Diynes; Ferricyanides; Fluoresceins; Hydrogen Peroxide; Inulin; Lasers; Liposomes; Permeability; Phosphatidylcholines; Photochemical Processes; Reactive Oxygen Species; Sodium Azide | 2013 |
Simulations of anionic lipid membranes: development of interaction-specific ion parameters and validation using NMR data.
Topics: Anions; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Osmotic Pressure; Phosphatidylcholines; Phosphatidylglycerols; Sodium | 2013 |
Characterizing the binding of annexin V to a lipid bilayer using molecular dynamics simulations.
Topics: Annexin A5; Calcium; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Stability | 2014 |
Binding, conformational transition and dimerization of amyloid-β peptide on GM1-containing ternary membrane: insights from molecular dynamics simulation.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Cholesterol; G(M1) Ganglioside; Humans; Hydrogen Bonding; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Sequence Data; Peptide Fragments; Phosphatidylcholines; Protein Binding; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Structure, Secondary | 2013 |
Association dynamics and linear and nonlinear optical properties of an N-acetylaladanamide probe in a POPC membrane.
Topics: 2-Naphthylamine; Acetamides; Models, Molecular; Molecular Dynamics Simulation; Optical Fibers; Optical Phenomena; Phosphatidylcholines; Quantum Theory | 2013 |
Carboxyl-terminated PAMAM dendrimer interaction with 1-palmitoyl-2-oleoyl phosphocholine bilayers.
Topics: Dendrimers; Fluoresceins; Fluorescent Dyes; Lipid Bilayers; Permeability; Phosphatidylcholines | 2014 |
Different effects of Alzheimer's peptide Aβ(1-40) oligomers and fibrils on supported lipid membranes.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cell Membrane; Humans; Lipid Bilayers; Microscopy, Atomic Force; Neurons; Peptide Fragments; Phosphatidylcholines; Phosphatidylserines | 2013 |
Preparation of liposomes: a novel application of microengineered membranes--from laboratory scale to large scale.
Topics: Chemical Engineering; Drug Carriers; Ethanol; Liposomes; Microfluidics; Microscopy, Electron, Transmission; Nanoparticles; Nickel; Particle Size; Phosphatidylcholines; Porosity | 2013 |
Molecular dynamics simulations of ion conductance in field-stabilized nanoscale lipid electropores.
Topics: Chlorides; Computer Simulation; Electric Conductivity; Ion Transport; Ions; Lipid Bilayers; Molecular Dynamics Simulation; Nanopores; Nonlinear Dynamics; Phosphatidylcholines; Potassium; Potassium Chloride; Sodium; Sodium Chloride; Water | 2013 |
Aggregation of oligoarginines at phospholipid membranes: molecular dynamics simulations, time-dependent fluorescence shift, and biomimetic colorimetric assays.
Topics: 2-Naphthylamine; Adsorption; Arginine; Biomimetics; Colorimetry; Dextrans; Fluorescence; Fluorescent Dyes; Laurates; Lipid Bilayers; Lysine; Membrane Potentials; Molecular Dynamics Simulation; Mycophenolic Acid; Peptides; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Polyacetylene Polymer; Polymers; Polyynes | 2013 |
Thermal fluctuations and bending rigidity of bilayer membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Temperature | 2013 |
Acylthioureas as anion transporters: the effect of intramolecular hydrogen bonding.
Topics: Anions; Chlorides; Crystallography, X-Ray; Hydrogen Bonding; Lipid Bilayers; Models, Molecular; Molecular Structure; Nitrates; Phosphatidylcholines; Quantum Theory; Thiourea | 2014 |
Phosphatidylcholine attenuates aggregation of nonsteroidal anti-inflammatory drugs with bile acid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Membrane; Cholic Acid; Computer Simulation; Hydrophobic and Hydrophilic Interactions; Indomethacin; Liposomes; Micelles; Models, Chemical; Phosphatidylcholines | 2013 |
Concentration effects of sumatriptan on the properties of model membranes by molecular dynamics simulations.
Topics: Cell Membrane; Dose-Response Relationship, Drug; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Sumatriptan | 2013 |
The transmembrane domains of the bacterial cell division proteins FtsB and FtsL form a stable high-order oligomer.
Topics: Cell Cycle Proteins; Cell Division; Cell Membrane; Detergents; Escherichia coli; Escherichia coli Proteins; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Kinetics; Lipid Bilayers; Membrane Proteins; Models, Biological; Peptide Fragments; Phosphatidylcholines; Phosphorylcholine; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Stability; Protein Structure, Secondary | 2013 |
Reactive oxygen species at phospholipid bilayers: distribution, mobility and permeation.
Topics: Diffusion; Hydrogen Bonding; Hydrogen Peroxide; Hydroxyl Radical; Kinetics; Lipid Bilayers; Lipid Peroxidation; Membrane Fluidity; Molecular Dynamics Simulation; Oxygen; Permeability; Phosphatidylcholines; Singlet Oxygen; Superoxides; Thermodynamics; Water | 2014 |
NBD-labeled cholesterol analogues in phospholipid bilayers: insights from molecular dynamics.
Topics: 4-Chloro-7-nitrobenzofurazan; Cholesterol; Deuterium; Fluorescent Dyes; Hydrogen Bonding; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Water | 2013 |
Membrane remodeling by α-synuclein and effects on amyloid formation.
Topics: Adenosine; alpha-Synuclein; Amyloid; Cholesterol; Circular Dichroism; Glycerophospholipids; Indicators and Reagents; Lipid Bilayers; Lipids; Membranes, Artificial; Microscopy, Electron, Transmission; Microtubules; Neutrons; Phosphatidylcholines; Spectrophotometry, Ultraviolet; Tryptophan | 2013 |
Membrane driven spatial organization of GPCRs.
Topics: Amino Acid Sequence; Cell Membrane; Cholesterol; Humans; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Sequence Data; Phosphatidylcholines; Protein Conformation; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sequence Homology, Amino Acid | 2013 |
A new design for nucleolipid-based Ru(III) complexes as anticancer agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coordination Complexes; Drug Design; Fatty Acids, Monounsaturated; Humans; Neoplasms; Phosphatidylcholines; Quaternary Ammonium Compounds; Ruthenium; Uridine | 2013 |
Ion channel stability of Gramicidin A in lipid bilayers: effect of hydrophobic mismatch.
Topics: Dimyristoylphosphatidylcholine; Gramicidin; Hydrophobic and Hydrophilic Interactions; Ion Channels; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Structure, Secondary; Thermodynamics | 2014 |
A remarkable self-organization process as the origin of primitive functional cells.
Topics: Cell-Free System; Green Fluorescent Proteins; Liposomes; Phosphatidylcholines; Protein Biosynthesis; Transcription, Genetic | 2013 |
The structural basis of cholesterol accessibility in membranes.
Topics: Cell Membrane; Cholesterol; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines | 2013 |
Simulating G protein-coupled receptors in native-like membranes: from monomers to oligomers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Dimyristoylphosphatidylcholine; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Conformation; Protein Multimerization; Receptors, Serotonin, 5-HT2; Software | 2013 |
Investigating the interaction between peptides of the amphipathic helix of Hcf106 and the phospholipid bilayer by solid-state NMR spectroscopy.
Topics: Amino Acid Sequence; Galactolipids; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Proteins; Models, Biological; Molecular Sequence Data; Peptides; Phosphatidylcholines; Plant Proteins; Protein Structure, Secondary; Protein Structure, Tertiary; Thylakoids | 2014 |
Importance of indole N-H hydrogen bonding in the organization and dynamics of gramicidin channels.
Topics: Amino Acid Sequence; Circular Dichroism; Gramicidin; Hydrogen Bonding; Indoles; Lipid Bilayers; Models, Biological; Molecular Sequence Data; Phosphatidylcholines; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Tryptophan | 2014 |
Sensing small molecule interactions with lipid membranes by local pH modulation.
Topics: Cholesterol; Hydrogen-Ion Concentration; Lipid Bilayers; Membranes, Artificial; Microscopy, Fluorescence; Phosphatidylcholines; Tetracaine | 2013 |
Robust measurement of membrane bending moduli using light sheet fluorescence imaging of vesicle fluctuations.
Topics: Fluorescence; Humans; Microscopy, Fluorescence; Monomeric GTP-Binding Proteins; Particle Size; Phosphatidylcholines; Surface Properties | 2013 |
Low PIP(2) molar fractions induce nanometer size clustering in giant unilamellar vesicles.
Topics: Boron Compounds; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositol 4,5-Diphosphate; Unilamellar Liposomes | 2014 |
Engineering antimicrobial peptides with improved antimicrobial and hemolytic activities.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antimicrobial Cationic Peptides; Biological Transport; Cell Membrane; Diffusion; Hemolysis; Humans; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Microbial Sensitivity Tests; Molecular Dynamics Simulation; Molecular Mimicry; Molecular Sequence Data; Peptide Library; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Protein Engineering; Pseudomonas aeruginosa; Thermodynamics | 2013 |
A microscopic view of phospholipid insertion into biological membranes.
Topics: Biomimetic Materials; Ethyl Chloride; Linear Models; Lipid Bilayers; Membranes, Artificial; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines; Phospholipids; Probability; Time Factors | 2014 |
Ca(2+) modulating α-synuclein membrane transient interactions revealed by solution NMR spectroscopy.
Topics: Adenosine; alpha-Synuclein; Apolipoprotein A-I; Calcium; Cell Membrane; Glycerophospholipids; Humans; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Protein Binding | 2014 |
In vitro membrane protein synthesis inside cell-sized vesicles reveals the dependence of membrane protein integration on vesicle volume.
Topics: Acriflavine; Antiporters; Cell-Free System; DNA; Escherichia coli; Escherichia coli Proteins; Ethidium; Fluorescent Dyes; Hydrogen-Ion Concentration; Membrane Proteins; Phosphatidylcholines; Plasmids; Unilamellar Liposomes | 2014 |
Photodynamic therapy of Porphyromonas gingivalis via liposome-encapsulated sensitizers.
Topics: Bacterial Adhesion; Colony Count, Microbial; Fatty Acids, Monounsaturated; Humans; Indoles; Isoindoles; Liposomes; Membrane Proteins; Organometallic Compounds; Periodontitis; Phosphatidylcholines; Photochemotherapy; Photosensitizing Agents; Porphyromonas gingivalis; Protein Binding; Quaternary Ammonium Compounds; Zinc Compounds | 2013 |
Transmembrane fragment structures of amyloid precursor protein depend on membrane surface curvature.
Topics: Amino Acid Sequence; Amyloid beta-Protein Precursor; Cell Membrane; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Surface Properties | 2014 |
Cholesterol's aliphatic side chain modulates membrane properties.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cell Membrane; Cholesterol; Lipid Bilayers; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Structure-Activity Relationship | 2013 |
Modeling of peptaibol analogues incorporating nonpolar α,α-dialkyl glycines shows improved α-helical preorganization and spontaneous membrane permeation.
Topics: Cell Membrane Permeability; Glycine; Molecular Dynamics Simulation; Peptaibols; Phosphatidylcholines; Protein Structure, Secondary; Water | 2014 |
Molecular origins of bending rigidity in lipids with isolated and conjugated double bonds: the effect of cholesterol.
Topics: Cholesterol; Linoleic Acids, Conjugated; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines | 2014 |
Structural properties of POPC monolayers under lateral compression: computer simulations analysis.
Topics: Air; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Phosphatidylcholines; Surface Properties; Water | 2014 |
Unveiling the membrane-binding properties of N-terminal and C-terminal regions of G protein-coupled receptor kinase 5 by combined optical spectroscopies.
Topics: Binding Sites; G-Protein-Coupled Receptor Kinase 5; Humans; Lipid Bilayers; Phosphatidylcholines; Spectrum Analysis | 2014 |
Molecular dynamics simulation of the partitioning of benzocaine and phenytoin into a lipid bilayer.
Topics: Anesthetics, Local; Benzocaine; Lipid Bilayers; Molecular Dynamics Simulation; Permeability; Phenytoin; Phosphatidylcholines; Thermodynamics | 2014 |
Physical damage on giant vesicles membrane as a result of methylene blue photoirradiation.
Topics: Light; Lipid Bilayers; Methylene Blue; Oxidation-Reduction; Phosphatidylcholines; Unilamellar Liposomes | 2014 |
HIV gp41 fusion peptide increases membrane ordering in a cholesterol-dependent fashion.
Topics: Amino Acid Sequence; Cholesterol; HIV Envelope Protein gp41; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols | 2014 |
Plasticity and conformational equilibria of influenza fusion peptides in model lipid bilayers.
Topics: Amino Acid Sequence; Lipid Bilayers; Models, Molecular; Molecular Dynamics Simulation; Molecular Sequence Data; Orthomyxoviridae; Phosphatidylcholines; Protein Conformation; Protein Multimerization; Viral Fusion Proteins | 2014 |
Controlled particle collision leads to direct observation of docking and fusion of lipid droplets in an optical trap.
Topics: Liposomes; Optical Tweezers; Particle Size; Phosphatidylcholines; Triolein | 2014 |
Molecular dynamics simulations of the adenosine A2a receptor in POPC and POPE lipid bilayers: effects of membrane on protein behavior.
Topics: Cell Membrane; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Principal Component Analysis; Protein Conformation; Receptor, Adenosine A2A | 2014 |
Predicting partition coefficients of Polyfluorinated and organosilicon compounds using polyparameter linear free energy relationships (PP-LFERs).
Topics: Air; Alcohols; Fluorocarbons; Hydrocarbons, Fluorinated; Liposomes; Models, Chemical; Octanols; Olive Oil; Organosilicon Compounds; Phosphatidylcholines; Plant Oils; Water | 2014 |
Surface tensiometry of apolipoprotein B domains at lipid interfaces suggests a new model for the initial steps in triglyceride-rich lipoprotein assembly.
Topics: Amino Acid Sequence; Apolipoproteins B; Humans; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Protein Biosynthesis; Protein Structure, Secondary; Protein Structure, Tertiary; Surface Properties; Triglycerides; Triolein; Water | 2014 |
Small-angle scattering gives direct structural information about a membrane protein inside a lipid environment.
Topics: Archaeal Proteins; Bacteriorhodopsins; Halobacterium; Lipid Bilayers; Membranes, Artificial; Models, Molecular; Neutron Diffraction; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Scattering, Small Angle; X-Ray Diffraction | 2014 |
Lipid membranes as solvents for carbon nanoparticles.
Topics: Alkanes; Fullerenes; Lipid Bilayers; Membrane Lipids; Models, Chemical; Models, Molecular; Nanotechnology; Nanotubes, Carbon; Phosphatidylcholines; Solubility; Thermodynamics | 2014 |
Study of orientation and penetration of LAH4 into lipid bilayer membranes: pH and composition dependence.
Topics: Antimicrobial Cationic Peptides; Hydrogen-Ion Concentration; Lipid Bilayers; Molecular Dynamics Simulation; Peptides; Phosphatidylcholines; Phosphatidylglycerols | 2014 |
Structure-activity relationship of the antimicrobial peptide gomesin: the role of peptide hydrophobicity in its interaction with model membranes.
Topics: Animals; Antimicrobial Cationic Peptides; Calorimetry; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Phosphatidylcholines; Phosphatidylglycerols; Spiders; Static Electricity; Structure-Activity Relationship; Surface Properties; Thermodynamics | 2014 |
Push-pull mechanism for lipid raft formation.
Topics: Cell Membrane; Cholesterol; Eukaryotic Cells; Membrane Microdomains; Molecular Structure; Phosphatidylcholines | 2014 |
Nanosecond lipid dynamics in membranes containing cholesterol.
Topics: Cholesterol; Dimyristoylphosphatidylcholine; Lipid Bilayers; Neutron Diffraction; Phosphatidylcholines; Scattering, Small Angle; Time Factors | 2014 |
Tris-thiourea tripodal-based molecules as chloride transmembrane transporters: insights from molecular dynamics simulations.
Topics: Chlorides; Diffusion; Ethylenediamines; Lipid Bilayers; Models, Molecular; Molecular Dynamics Simulation; Permeability; Phosphatidylcholines; Thiourea | 2014 |
Interactions of beta-blockers with model lipid membranes: molecular view of the interaction of acebutolol, oxprenolol, and propranolol with phosphatidylcholine vesicles by time-dependent fluorescence shift and molecular dynamics simulations.
Topics: Acebutolol; Adrenergic beta-Antagonists; Fluorescence; Fluorescent Dyes; Glycerol; Lipid Bilayers; Liposomes; Membrane Lipids; Molecular Dynamics Simulation; Oxprenolol; Phosphatidylcholines; Propranolol | 2014 |
Membrane remodeling processes induced by phospholipase action.
Topics: Hydrolysis; Membranes, Artificial; Microscopy, Fluorescence; Phosphatidylcholines; Phospholipases; Phospholipids | 2014 |
Thermal annealing triggers collapse of biphasic supported lipid bilayers into multilayer islands.
Topics: Lipid Bilayers; Phosphatidylcholines; Phospholipids | 2014 |
Solid-phase extraction approach for phospholipids profiling by titania-coated silica microspheres prior to reversed-phase liquid chromatography-evaporative light scattering detection and tandem mass spectrometry analysis.
Topics: Adsorption; Chromatography, Reverse-Phase; Dimyristoylphosphatidylcholine; Humans; Lysophospholipids; Microscopy, Electron, Scanning; Microspheres; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Reproducibility of Results; Silicon Dioxide; Solid Phase Extraction; Spectrophotometry; Tandem Mass Spectrometry; Thermodynamics; Titanium; X-Ray Diffraction | 2014 |
Biophysical implications of sphingosine accumulation in membrane properties at neutral and acidic pH.
Topics: Cholesterol; Fluorescence Polarization; Hydrogen-Ion Concentration; Liposomes; Membrane Fluidity; Membrane Microdomains; Phase Transition; Phosphatidylcholines; Sphingomyelins; Sphingosine; Static Electricity | 2014 |
A molecular dynamic study of cholesterol rich lipid membranes: comparison of electroporation protocols.
Topics: Cell Membrane; Cholesterol; Electroporation; Lipid Bilayers; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines; Time Factors | 2014 |
Indolicidin binding induces thinning of a lipid bilayer.
Topics: Amino Acid Sequence; Antimicrobial Cationic Peptides; Lipid Bilayers; Molecular Sequence Data; Phosphatidylcholines; Protein Binding | 2014 |
Effects of magnetic cobalt ferrite nanoparticles on biological and artificial lipid membranes.
Topics: Cells, Cultured; Cobalt; Erythrocyte Membrane; Humans; Lipid Bilayers; Magnetite Nanoparticles; Materials Testing; Membrane Fluidity; Molecular Conformation; Phosphatidylcholines | 2014 |
Peptide-membrane interactions of arginine-tryptophan peptides probed using quartz crystal microbalance with dissipation monitoring.
Topics: Amino Acid Sequence; Arginine; Cell Membrane; Liposomes; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary; Quartz Crystal Microbalance Techniques; Tryptophan | 2014 |
Phosphatidylinositol-4,5-bisphosphate enhances anionic lipid demixing by the C2 domain of PKCα.
Topics: Calcium; Cations, Divalent; Fluorescence; Membranes, Artificial; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositol 4,5-Diphosphate; Protein Kinase C-alpha; Protein Structure, Tertiary | 2014 |
Biocompatible cationic lipids for the formulation of liposomal DNA vectors.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Biocompatible Materials; DNA; Lipid Bilayers; Phosphatidylcholines; Phosphatidylethanolamines; Unilamellar Liposomes | 2014 |
Selective oxidation of D-amino acids catalyzed by oligolamellar liposomes intercalated with D-amino acid oxidase.
Topics: Alanine; Amino Acids; Animals; Catalysis; Colloids; D-Amino-Acid Oxidase; Hydrogen-Ion Concentration; Kidney; Lipid Bilayers; Liposomes; Lysosomes; Oxygen; Permeability; Phosphatidylcholines; Serine; Stereoisomerism; Substrate Specificity; Swine; Temperature | 2014 |
Mmp-9 responsive PEG cleavable nanovesicles for efficient delivery of chemotherapeutics to pancreatic cancer.
Topics: Animals; Antineoplastic Agents; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Deoxycytidine; Drug Carriers; Drug Delivery Systems; Extracellular Matrix; Female; Gemcitabine; Glutathione; Humans; Hydrolysis; Lipid Bilayers; Lipopeptides; Matrix Metalloproteinase 9; Mice; Mice, Nude; Nanoparticles; Pancreatic Neoplasms; Phosphatidylcholines; Polyethylene Glycols; Transport Vesicles | 2014 |
Cholesterol level affects surface charge of lipid membranes in saline solution.
Topics: Cell Membrane; Cholesterol; Drug Delivery Systems; Humans; Lipid Bilayers; Liposomes; Membrane Lipids; Molecular Dynamics Simulation; Phosphatidylcholines; Sodium Chloride | 2014 |
Characterizing the structure of lipodisq nanoparticles for membrane protein spectroscopic studies.
Topics: Lipid Bilayers; Magnetic Resonance Spectroscopy; Maleates; Membrane Proteins; Nanoparticles; Phosphatidylcholines; Phosphatidylglycerols; Polystyrenes | 2015 |
Transmembrane recognition of the semaphorin co-receptors neuropilin 1 and plexin A1: coarse-grained simulations.
Topics: Cell Membrane; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Nerve Tissue Proteins; Neuropilin-1; Phosphatidylcholines; Protein Multimerization; Protein Structure, Quaternary; Receptors, Cell Surface; Semaphorins; Thermodynamics | 2014 |
Bacterial RTX toxins allow acute ATP release from human erythrocytes directly through the toxin pore.
Topics: Adenosine Triphosphate; Aggregatibacter actinomycetemcomitans; Animals; Bacterial Proteins; Connexins; Erythrocytes; Escherichia coli Proteins; Gene Knockout Techniques; Hemoglobins; Hemolysin Proteins; Hemolysis; Humans; Membranes, Artificial; Mice; Nerve Tissue Proteins; Phosphatidylcholines; Porosity | 2014 |
The effects of lipids and surfactants on TLR5-proteoliposome functionality for flagellin detection using surface plasmon resonance biosensing.
Topics: Biosensing Techniques; Dimyristoylphosphatidylcholine; Escherichia coli; Escherichia coli Proteins; Flagellin; Fluorescence Polarization; Humans; Immobilized Proteins; Kinetics; Lipid Bilayers; Lipids; Membrane Fluidity; Octoxynol; Phosphatidylcholines; Phosphatidylethanolamines; Protein Binding; Proteolipids; Reproducibility of Results; Surface Plasmon Resonance; Surface-Active Agents; Time Factors; Toll-Like Receptor 5 | 2014 |
Dehydroergosterol as an analogue for cholesterol: why it mimics cholesterol so well-or does it?
Topics: Cholesterol; Ergosterol; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Quantum Theory; Spectrometry, Fluorescence; Unilamellar Liposomes; Water | 2014 |
Interactions of serum with polyelectrolyte-stabilized liposomes: Cryo-TEM studies.
Topics: Animals; Cattle; Cryoelectron Microscopy; Electrolytes; Fluoresceins; Hydrodynamics; Liposomes; Microscopy, Electron, Transmission; Phosphatidylcholines; Polyamines; Polyelectrolytes; Polymers; Pressure; Serum; Static Electricity | 2014 |
On the design of supramolecular assemblies made of peptides and lipid bilayers.
Topics: Alamethicin; Circular Dichroism; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Macromolecular Substances; Magnetic Resonance Spectroscopy; Molecular Conformation; Phosphatidylcholines; Protein Engineering; Protein Structure, Secondary | 2014 |
Modelling Ser129 phosphorylation inhibits membrane binding of pore-forming alpha-synuclein oligomers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; alpha-Synuclein; Cell Membrane; Humans; Mutation; Phosphatidylcholines; Phosphorylation; Porosity; Protein Binding; Protein Multimerization; Protein Structure, Quaternary; Serine; Temperature; Unilamellar Liposomes | 2014 |
Amyloids of alpha-synuclein affect the structure and dynamics of supported lipid bilayers.
Topics: Adsorption; alpha-Synuclein; Amyloid; Benzothiazoles; Lipid Bilayers; Liposomes; Mutant Proteins; Phosphatidylcholines; Phosphatidylglycerols; Protein Aggregates; Protein Binding; Staining and Labeling; Thiazoles | 2014 |
α-Synuclein-induced membrane remodeling is driven by binding affinity, partition depth, and interleaflet order asymmetry.
Topics: alpha-Synuclein; Lipids; Membranes, Artificial; Phosphatidylcholines; Phosphatidylglycerols | 2014 |
Probing the association of triblock copolymers with supported lipid membranes using microcantilevers.
Topics: Diffusion; Lipid Bilayers; Models, Theoretical; Phosphatidylcholines; Poloxamer; Solubility; Temperature | 2014 |
Lysophospholipid acyltransferases mediate phosphatidylcholine diversification to achieve the physical properties required in vivo.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; 1,2-Dipalmitoylphosphatidylcholine; Animals; Chemokines; CHO Cells; Cricetinae; Cricetulus; Cytokines; Lung Injury; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Surface-Active Agents | 2014 |
Digestion of phospholipids after secretion of bile into the duodenum changes the phase behavior of bile components.
Topics: Bile; Bile Acids and Salts; Dietary Fats; Duodenum; Fatty Acids; Gastrointestinal Tract; Humans; Lecithins; Light; Lipids; Micelles; Molecular Dynamics Simulation; Phosphatidylcholines; Phospholipids; Scattering, Radiation | 2014 |
Statistical analysis of vesicle morphology dynamics based on a free energy landscape.
Topics: Data Interpretation, Statistical; Models, Theoretical; Osmotic Pressure; Phosphatidylcholines; Phosphatidylglycerols; Principal Component Analysis | 2014 |
Structural and Thermodynamic Insight into Spontaneous Membrane-Translocating Peptides Across Model PC/PG Lipid Bilayers.
Topics: Cell Membrane; Cell-Penetrating Peptides; Entropy; Hydrophobic and Hydrophilic Interactions; Kinetics; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylglycerols; Protein Stability; Thermodynamics; Water | 2015 |
Driving a planar model system into the 3(rd) dimension: generation and control of curved pore-spanning membrane arrays.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Ions; Lipid Bilayers; Materials Testing; Membranes, Artificial; Microscopy, Confocal; Osmosis; Phosphatidylcholines; Pressure; Protein Structure, Tertiary; Proteins; Rats; Silicon; Silicon Dioxide; Solvents; Temperature; Tin Compounds | 2014 |
Interaction of amphotericin B with lipid monolayers.
Topics: Amphotericin B; Ergosterol; Phosphatidylcholines | 2014 |
Mastoparan peptide causes mitochondrial permeability transition not by interacting with specific membrane proteins but by interacting with the phospholipid phase.
Topics: Animals; Cyclosporine; Intercellular Signaling Peptides and Proteins; Male; Membrane Lipids; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Peptides; Phosphatidylcholines; Rats; Stereoisomerism; Wasp Venoms | 2014 |
Membrane lipids protected from oxidation by red wine tannins: a proton NMR study.
Topics: Antioxidants; Catechin; Chlorobenzenes; Dimyristoylphosphatidylcholine; Dose-Response Relationship, Drug; Kinetics; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Lipids; Molecular Dynamics Simulation; Molecular Structure; Oxidation-Reduction; Phosphatidylcholines; Time Factors; Wine | 2014 |
DL-/PO-phosphatidylcholine restores restraint stress-induced depression-related behaviors and spatial memory impairment.
Topics: Animals; Depressive Disorder; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hypothalamus; Male; Maze Learning; Memory Disorders; Mice, Inbred C57BL; Motor Activity; Neuropsychological Tests; Phosphatidylcholines; Phosphorylation; Proto-Oncogene Proteins c-akt; Psychotropic Drugs; Restraint, Physical; Spatial Memory; Stress, Psychological | 2014 |
Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE.
Topics: Arginine; Aspartic Acid; Biological Transport; Escherichia coli; Escherichia coli Proteins; Gene Expression; Hydrogen Bonding; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Structure, Secondary; Protein Structure, Tertiary; Protons; Recombinant Proteins; Symporters; Thermodynamics; Xylose | 2014 |
Conformational and thermodynamic properties of non-canonical α,α-dialkyl glycines in the peptaibol Alamethicin: molecular dynamics studies.
Topics: Alamethicin; Amino Acids; Glycine; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Structure, Secondary; Thermodynamics | 2014 |
Phase coexistence in single-lipid membranes induced by buffering agents.
Topics: Lipid Bilayers; Phosphatidylcholines | 2014 |
Calibration of Distribution Analysis of the Depth of Membrane Penetration Using Simulations and Depth-Dependent Fluorescence Quenching.
Topics: Calibration; Cell Membrane Permeability; Cell-Penetrating Peptides; Diphtheria Toxin; Lipid Bilayers; Molecular Dynamics Simulation; Oxadiazoles; Phosphatidylcholines; Spectrometry, Fluorescence | 2015 |
Watching individual molecules flex within lipid membranes using SERS.
Topics: Fatty Acids, Monounsaturated; Gold; Lipid Bilayers; Metal Nanoparticles; Phosphatidylcholines; Quaternary Ammonium Compounds; Spectrum Analysis, Raman | 2014 |
Preorganized bis-thioureas as powerful anion carriers: chloride transport by single molecules in large unilamellar vesicles.
Topics: Anions; Chlorides; Cholesterol; Humans; Ion Transport; Models, Molecular; Nitrates; Phosphatidylcholines; Thiourea; Unilamellar Liposomes | 2014 |
Interactions of divalent calcium ions with head groups of zwitterionic phosphatidylcholine liposomal membranes.
Topics: Calcium; Lipid Bilayers; Liposomes; Membrane Fluidity; Osmotic Pressure; Phosphatidylcholines | 2014 |
Lipid structure in triolein lipid droplets.
Topics: Cholesterol; Dimerization; Lipid Bilayers; Lipid Droplets; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Solvents; Triolein; Water | 2014 |
X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.
Topics: Allosteric Regulation; Animals; Apoproteins; Binding Sites; Binding, Competitive; Caenorhabditis elegans; Cell Membrane; Chloride Channels; Crystallography, X-Ray; Cysteine Loop Ligand-Gated Ion Channel Receptors; Drug Partial Agonism; Glutamic Acid; Ion Channel Gating; Ivermectin; Ligands; Models, Molecular; Movement; Phosphatidylcholines; Protein Binding; Protein Multimerization; Protein Structure, Tertiary; Structure-Activity Relationship | 2014 |
Interaction of Bestrophin-1 with 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) in surface films.
Topics: Animals; Bestrophins; Blotting, Western; Chloride Channels; Chromatography, Gel; Dogs; Eye Proteins; Humans; Madin Darby Canine Kidney Cells; Phosphatidylcholines; Protein Binding; Surface Properties | 2014 |
Diffusion in low-dimensional lipid membranes.
Topics: Diffusion; Humans; Influenza A virus; Influenza, Human; Lipid Bilayers; Microscopy, Atomic Force; Models, Molecular; Phosphatidylcholines; Phosphatidylethanolamines; Viral Matrix Proteins | 2014 |
Membrane properties of cholesterol analogs with an unbranched aliphatic side chain.
Topics: Alkanes; Androstenols; Cholesterol; Diffusion; Magnetic Resonance Spectroscopy; Permeability; Phosphatidylcholines; Phospholipids; Unilamellar Liposomes | 2014 |
Single lipid extraction: the anchoring strength of cholesterol in liquid-ordered and liquid-disordered phases.
Topics: Cholesterol; Hydrogen Bonding; Lipid Bilayers; Microscopy, Atomic Force; Molecular Dynamics Simulation; Phase Transition; Phosphatidylcholines; Phosphatidylethanolamines; Spectrum Analysis; Unilamellar Liposomes | 2014 |
A sub-nanometre view of how membrane curvature and composition modulate lipid packing and protein recruitment.
Topics: Cell Adhesion; Cell Line, Transformed; Cell Membrane; Cell Shape; Dimyristoylphosphatidylcholine; Epithelial Cells; Fatty Acids; Gene Expression; Green Fluorescent Proteins; GTPase-Activating Proteins; Humans; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Recombinant Fusion Proteins; Retinal Pigment Epithelium | 2014 |
Structural investigation of the transmembrane domain of KCNE1 in proteoliposomes.
Topics: Amino Acid Substitution; Humans; Lipid Bilayers; Liposomes; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylglycerols; Potassium Channels, Voltage-Gated; Protein Structure, Secondary; Protein Structure, Tertiary; Thermodynamics | 2014 |
Microsecond molecular dynamics simulations of lipid mixing.
Topics: Cholesterol; Lipid Bilayers; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Sodium Chloride; Thermodynamics; Time Factors; Water | 2014 |
Molecular simulation of the concentration-dependent interaction of hydrophobic drugs with model cellular membranes.
Topics: Cell Membrane; Diffusion; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Dynamics Simulation; Paclitaxel; Permeability; Phosphatidylcholines; Rotation; Water | 2014 |
Not only oxidation of cardiolipin affects the affinity of cytochrome C for lipid bilayers.
Topics: Animals; Cardiolipins; Circular Dichroism; Cytochromes c; Fish Proteins; Fluorescence; Horses; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Liposomes; Mitochondrial Membranes; Models, Biological; Molecular Structure; Myocardium; Oxidation-Reduction; Phosphatidylcholines; Phosphatidylethanolamines; Phosphorylcholine; Pyrenes; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tuna | 2014 |
Triptan partition in model membranes.
Topics: Drug Stability; Hydrogen Bonding; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Structure; Phosphatidylcholines; Piperidines; Protons; Solubility; Structure-Activity Relationship; Sumatriptan; Tryptamines; Water | 2014 |
Besides fibrillization: putative role of the peptide fragment 71-82 on the structural and assembly behavior of α-synuclein.
Topics: alpha-Synuclein; Amyloid; Circular Dichroism; Humans; Lipid Bilayers; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Osmolar Concentration; Peptide Fragments; Phosphatidylcholines; Phosphatidylglycerols; Protein Aggregation, Pathological; Protein Conformation; Protein Interaction Domains and Motifs; Protein Stability; Protein Structure, Secondary; Protein Unfolding; Solubility; Temperature | 2014 |
Molecular insight into the effect of lipid bilayer environments on thrombospondin-1 and calreticulin interactions.
Topics: Binding Sites; Calreticulin; Humans; Hydrogen Bonding; Lipid Bilayers; Low Density Lipoprotein Receptor-Related Protein-1; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Interaction Domains and Motifs; Protein Structure, Quaternary; Thrombospondin 1 | 2014 |
The Curvature Induction of Surface-Bound Antimicrobial Peptides Piscidin 1 and Piscidin 3 Varies with Lipid Chain Length.
Topics: Antimicrobial Cationic Peptides; Dimyristoylphosphatidylcholine; Fish Proteins; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Protein Structure, Secondary; Thermodynamics | 2015 |
Atomistic models of general anesthetics for use in in silico biological studies.
Topics: Anesthetics, General; Cell Membrane; Computer Simulation; Ion Channels; Lipid Bilayers; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines; Reproducibility of Results | 2014 |
Palmitoylation as a key factor to modulate SP-C-lipid interactions in lung surfactant membrane multilayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Lipoylation; Membrane Lipids; Membranes; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Structure, Secondary; Pulmonary Surfactant-Associated Protein C; Pulmonary Surfactants; Spectroscopy, Fourier Transform Infrared; Surface Properties; Swine; Temperature | 2015 |
Comparative EPR studies on lipid bilayer properties in nanodiscs and liposomes.
Topics: Algorithms; Apolipoprotein A-I; Dimyristoylphosphatidylcholine; Electron Spin Resonance Spectroscopy; Kinetics; Lipid Bilayers; Liposomes; Membrane Fluidity; Membrane Proteins; Nanostructures; Phosphatidylcholines | 2015 |
Interactions of PAMAM dendrimers with negatively charged model biomembranes.
Topics: Dendrimers; Light; Lipid Bilayers; Neutron Diffraction; Phosphatidylcholines; Phosphatidylserines; Quartz Crystal Microbalance Techniques; Scattering, Radiation | 2014 |
Enhanced Sampling of Coarse-Grained Transmembrane-Peptide Structure Formation from Hydrogen-Bond Replica Exchange.
Topics: Amino Acid Sequence; Hydrogen Bonding; Membrane Proteins; Molecular Dynamics Simulation; Molecular Sequence Data; Phosphatidylcholines; Protein Folding; Protein Structure, Secondary; Thermodynamics | 2015 |
pH-dependent promotion of phospholipid flip-flop by the KcsA potassium channel.
Topics: 4-Chloro-7-nitrobenzofurazan; Bacterial Proteins; Cholesterol; Hydrogen-Ion Concentration; Lipid Bilayers; Models, Molecular; Mutation; Phosphatidylcholines; Phospholipids; Potassium Channels; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Quaternary Ammonium Compounds | 2015 |
α-Tocopherol's Location in Membranes Is Not Affected by Their Composition.
Topics: alpha-Tocopherol; Humans; Lipid Bilayers; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Sphingomyelins; Surface Properties; Temperature; Thermodynamics; Water | 2015 |
Flip-flop of oleic acid in a phospholipid membrane: rate and mechanism.
Topics: Diffusion; Lipid Bilayers; Molecular Dynamics Simulation; Oleic Acid; Phosphatidylcholines; Phospholipids; Thermodynamics | 2014 |
Exploring the local elastic properties of bilayer membranes using molecular dynamics simulations.
Topics: Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Solvents; Thermodynamics | 2014 |
Fast membrane hemifusion via dewetting between lipid bilayers.
Topics: Electric Capacitance; Glycerides; Lipid Bilayers; Microfluidic Analytical Techniques; Phosphatidylcholines | 2014 |
Mechanism of a pH-induced peptide inserting into a POPC bilayer: a molecular dynamic study.
Topics: Hydrogen Bonding; Hydrogen-Ion Concentration; Lipid Bilayers; Membrane Proteins; Molecular Dynamics Simulation; Phosphatidylcholines | 2014 |
Cholesterol solubility limit in lipid membranes probed by small angle neutron scattering and MD simulations.
Topics: Cholesterol; Molecular Dynamics Simulation; Neutron Diffraction; Phosphatidylcholines; Phosphatidylserines; Scattering, Small Angle; Solubility; Unilamellar Liposomes | 2014 |
Light-driven directed proton transport across the liposomal membrane.
Topics: Hydrogen-Ion Concentration; Light; Lipid Bilayers; Liposomes; Molecular Structure; Phosphatidylcholines; Protons | 2014 |
Structure of membrane-active toxin from crab spider Heriaeus melloteei suggests parallel evolution of sodium channel gating modifiers in Araneomorphae and Mygalomorphae.
Topics: Amino Acid Sequence; Animals; Cell Membrane; Escherichia coli; Evolution, Molecular; Gene Expression; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Membrane Potentials; Models, Molecular; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sodium Channel Blockers; Spider Venoms; Spiders; Unilamellar Liposomes; Voltage-Gated Sodium Channels | 2015 |
Incorporation of pentacyclic triterpenes into mitochondrial membrane--studies on the interactions in model 2D lipid systems.
Topics: Betulinic Acid; Cardiolipins; Hydrogen Bonding; Mitochondrial Membranes; Models, Molecular; Pentacyclic Triterpenes; Phosphatidylcholines; Phosphatidylethanolamines; Thermodynamics; Triterpenes; Ursolic Acid | 2014 |
Incorporation of human growth hormone-2 into proteoliposome enhances tissue regeneration with anti-oxidant and anti-senescence activities.
Topics: Animals; Antioxidants; Apolipoprotein A-I; Cellular Senescence; Circular Dichroism; Densitometry; Escherichia coli; Female; Gene Expression Profiling; Gene Expression Regulation; Growth Hormone; Humans; Lipids; Lipoproteins, HDL; Monocytes; Oxygen; Phagocytosis; Phosphatidylcholines; Placental Hormones; Pregnancy; Proteolipids; Regeneration; Spectrometry, Fluorescence; Zebrafish | 2015 |
Role of lipid-mediated effects in β₂-adrenergic receptor dimerization.
Topics: Animals; Binding Sites; Cholesterol; Humans; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Membrane Lipids; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Adrenergic, beta-2; Thermodynamics | 2015 |
Preparation and mechanical characterisation of giant unilamellar vesicles by a microfluidic method.
Topics: Hemolysin Proteins; Microfluidic Analytical Techniques; Microscopy, Fluorescence; Oils; Phosphatidylcholines; Phospholipids; Rheology; Rhodamines; Unilamellar Liposomes; Water | 2015 |
A highly tilted membrane configuration for the prefusion state of synaptobrevin.
Topics: Amino Acid Sequence; Lipid Bilayers; Molecular Dynamics Simulation; Mutation; Phosphatidylcholines; R-SNARE Proteins | 2014 |
Voltage sensor gating charge transfer in a hERG potassium channel model.
Topics: Amino Acid Sequence; Electron Transport; Ether-A-Go-Go Potassium Channels; Humans; Ion Channel Gating; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Sequence Data; Phosphatidylcholines; Protein Conformation | 2014 |
Lipid vesicle shape analysis from populations using light video microscopy and computer vision.
Topics: Algorithms; Cholesterol; Image Processing, Computer-Assisted; Light; Microscopy, Video; Normal Distribution; Particle Size; Phosphatidylcholines; Suspensions; Unilamellar Liposomes | 2014 |
Hydrolysis of a lipid membrane by single enzyme molecules: accurate determination of kinetic parameters.
Topics: Biocatalysis; Coloring Agents; Humans; Hydrolysis; Kinetics; Liposomes; Membrane Lipids; Phosphatidylcholines; Phospholipases A2 | 2015 |
Molecular dynamics methods to predict peptide locations in membranes: LAH4 as a stringent test case.
Topics: Antimicrobial Cationic Peptides; Cell Membrane Permeability; Histidine; Kinetics; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylserines; Static Electricity; Thermodynamics; Water | 2015 |
Selenium as an alternative peptide label - comparison to fluorophore-labelled penetratin.
Topics: Biological Transport; Carrier Proteins; Cell-Penetrating Peptides; Cholesterol; Circular Dichroism; Drug Stability; Fluorescent Dyes; HeLa Cells; Humans; Liposomes; Molecular Weight; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary; Rhodamines; Selenium | 2015 |
Atomically detailed lipid bilayer models for the interpretation of small angle neutron and X-ray scattering data.
Topics: Lipid Bilayers; Models, Chemical; Neutron Diffraction; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Quantum Theory; Scattering, Radiation; X-Ray Diffraction | 2015 |
Cholesteryl ester diffusion, location and self-association constraints determine CETP activity with discoidal HDL: excimer probe study.
Topics: Apolipoprotein A-I; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Humans; Kinetics; Lipoproteins; Lipoproteins, HDL; Phosphatidylcholines; Recombinant Proteins | 2014 |
Phospholipid lateral diffusion in phosphatidylcholine-sphingomyelin-cholesterol monolayers; effects of oxidatively truncated phosphatidylcholines.
Topics: Algorithms; Cholesterol; Diffusion; Microscopy; Models, Chemical; Molecular Structure; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Sphingomyelins; Unilamellar Liposomes | 2015 |
Experimental determination and computational interpretation of biophysical properties of lipid bilayers enriched by cholesteryl hemisuccinate.
Topics: 2-Naphthylamine; Cholesterol; Cholesterol Esters; Dihydropyridines; Laurates; Lipid Bilayers; Liposomes; Molecular Dynamics Simulation; Phosphatidylcholines; Protons; Water | 2015 |
A thermodynamic signature of lipid segregation in biomembranes induced by a short peptide derived from glycoprotein gp36 of feline immunodeficiency virus.
Topics: Cholesterol; Circular Dichroism; Immunodeficiency Virus, Feline; Kinetics; Lipid Bilayers; Liposomes; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sphingomyelins; Thermodynamics; Viral Fusion Proteins | 2015 |
Effect of α-tocopherol on the hemin-catalyzed decomposition of 1-palmitoyl-2-linoleoyl-3-sn-phosphatidylcholine 13-hydroperoxide in micelles and liposomes.
Topics: alpha-Tocopherol; Catalysis; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Hemin; Lipid Peroxides; Liposomes; Magnetic Resonance Spectroscopy; Micelles; Phosphatidylcholines | 2014 |
Synthesis, in vitro and in vivo studies, and molecular modeling of N-alkylated dextromethorphan derivatives as non-competitive inhibitors of α3β4 nicotinic acetylcholine receptor.
Topics: Animals; Binding Sites; Cell Line; Dextromethorphan; Ligands; Lipid Bilayers; Male; Molecular Docking Simulation; Motor Activity; Nicotinic Antagonists; Patch-Clamp Techniques; Phosphatidylcholines; Protein Binding; Protein Structure, Tertiary; Rats; Rats, Wistar; Receptors, Nicotinic | 2014 |
Electroporation threshold of POPC lipid bilayers with incorporated polyoxyethylene glycol (C12E8).
Topics: Electroporation; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Structure; Phosphatidylcholines; Polyethylene Glycols | 2015 |
Self-assembly formation of lipid bilayer coatings on bare aluminum oxide: overcoming the force of interfacial water.
Topics: Algorithms; Aluminum Oxide; Biosensing Techniques; Catalysis; Hydrogen-Ion Concentration; Light; Lipid Bilayers; Lipids; Microscopy, Fluorescence; Phosphatidylcholines; Quartz Crystal Microbalance Techniques; Scattering, Radiation; Silicon Dioxide; Solvents; Static Electricity; Surface Properties; Water | 2015 |
Optimization of bicelle lipid composition and temperature for EPR spectroscopy of aligned membranes.
Topics: Dimyristoylphosphatidylcholine; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phospholipids; Temperature | 2015 |
Peptide-induced formation of a tethered lipid bilayer membrane on mesoporous silica.
Topics: Adsorption; Lipid Bilayers; Osmotic Pressure; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; Porosity; Silicon Dioxide; Unilamellar Liposomes | 2015 |
Reporter-encapsulated liposomes on graphene field effect transistors for signal enhanced detection of physiological enzymes.
Topics: Graphite; Kinetics; Liposomes; Microscopy, Electron, Scanning; Oxides; Phosphatidylcholines; Phospholipases A2; Picrates; Silicon Dioxide; Spectrophotometry; Substrate Specificity; Transistors, Electronic | 2015 |
Study of interactions between polymer nanoparticles and cell membranes at atomistic levels.
Topics: Cell Adhesion; Cell Membrane; Models, Molecular; Nanoparticles; Phosphatidylcholines; Polymers | 2015 |
Cholesterol stimulates and ceramide inhibits Sticholysin II-induced pore formation in complex bilayer membranes.
Topics: Animals; Cell Membrane; Cell Membrane Permeability; Ceramides; Cholesterol; Cnidarian Venoms; Fluoresceins; Fluorescence Polarization; Lipid Bilayers; Membrane Fluidity; Phosphatidylcholines; Sea Anemones; Surface Plasmon Resonance | 2015 |
Folding and self-association of atTic20 in lipid membranes: implications for understanding protein transport across the inner envelope membrane of chloroplasts.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Chloroplasts; Escherichia coli; Intracellular Membranes; Intrinsically Disordered Proteins; Liposomes; Membrane Transport Proteins; Molecular Sequence Data; Phosphatidylcholines; Protein Folding; Protein Multimerization; Protein Refolding; Protein Structure, Tertiary; Protein Transport | 2014 |
The dynamics of the G protein-coupled neuropeptide Y2 receptor in monounsaturated membranes investigated by solid-state NMR spectroscopy.
Topics: Carbon-13 Magnetic Resonance Spectroscopy; Cell Membrane; Fatty Acids, Monounsaturated; Humans; Models, Molecular; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Neuropeptide Y | 2015 |
Push and pull forces in lipid raft formation: the push can be as important as the pull.
Topics: Biomechanical Phenomena; Dimerization; Mechanical Phenomena; Membrane Microdomains; Phosphatidylcholines | 2015 |
Water-binding phospholipid nanodomains and phase-separated diacylglycerol nanodomains regulate enzyme reactions in lipid monolayers.
Topics: Diglycerides; Kinetics; Microscopy, Atomic Force; Phosphatidylcholines; Phospholipids; Water | 2015 |
Characterization of a novel thermophilic phospholipase B from Thermotoga lettingae TMO: applicability in enzymatic degumming of vegetable oils.
Topics: Cloning, Molecular; Enzyme Stability; Escherichia coli; Gram-Negative Anaerobic Straight, Curved, and Helical Rods; Half-Life; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lysophospholipase; Phosphatidylcholines; Phosphorus; Plant Oils; Solvents; Temperature | 2015 |
Modulation of Alzheimer's Aβ protofilament-membrane interactions by lipid headgroups.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Computer Simulation; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Static Electricity; Statistics, Nonparametric; Structure-Activity Relationship | 2015 |
X-DNA origami-networked core-supported lipid stratum.
Topics: Bacteriophage T4; Benzothiazoles; Cholesterol; Diamines; DNA, Single-Stranded; Fluorescent Dyes; Hydrogels; Ligases; Microscopy, Electron, Transmission; Nanostructures; Nucleic Acid Conformation; Organic Chemicals; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Quinolines; Viral Proteins; Xanthenes | 2015 |
Annular anionic lipids stabilize the integrin αIIbβ3 transmembrane complex.
Topics: Amino Acid Sequence; Humans; Molecular Dynamics Simulation; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phosphatidylserines; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Stability; Protein Structure, Secondary | 2015 |
Aromatic isophthalamides aggregate in lipid bilayers: evidence for a cooperative transport mechanism.
Topics: Anions; Bicarbonates; Biological Transport; Chlorides; Cholesterol; Diffusion; Lipid Bilayers; Organic Chemicals; Phosphatidylcholines; Phospholipids; Phthalic Acids; Protein Binding; Quaternary Ammonium Compounds; Solutions; Solvents; Spectrometry, Fluorescence | 2015 |
Design of a homogeneous multifunctional supported lipid membrane on layer-by-layer coated microcarriers.
Topics: Biotin; Drug Carriers; Lipid Bilayers; Liposomes; Particle Size; Phosphatidylcholines; Phosphatidylserines; Polyethylene Glycols; Silicon Dioxide; Streptavidin; Surface Properties | 2015 |
Membrane Association of the Diphtheria Toxin Translocation Domain Studied by Coarse-Grained Simulations and Experiment.
Topics: Diphtheria Toxin; Histidine; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Structure, Secondary | 2015 |
Microemulsions, modulated phases and macroscopic phase separation: a unified picture of rafts.
Topics: Cholesterol; Emulsions; Kinetics; Lipid Bilayers; Membrane Microdomains; Models, Chemical; Phase Transition; Phosphatidylcholines; Saccharomyces cerevisiae; Sphingomyelins; Thermodynamics; Vacuoles | 2015 |
Lipid bilayers: clusters, domains and phases.
Topics: Cholesterol; Emulsions; Kinetics; Lipid Bilayers; Membrane Microdomains; Membrane Proteins; Micelles; Models, Chemical; Monte Carlo Method; Phase Transition; Phosphatidylcholines; Thermodynamics | 2015 |
Visualizing monolayers with a water-soluble fluorophore to quantify adsorption, desorption, and the double layer.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Adsorption; Fluorescence; Fluorescent Dyes; Hydrogen-Ion Concentration; Osmolar Concentration; Phase Transition; Phosphatidylcholines; Rhodamine 123; Solubility; Surface Properties; Temperature; Water; Xanthenes | 2015 |
Predicting peptide vaccine candidates against H1N1 influenza virus through theoretical approaches.
Topics: Animals; Epitopes; Hemagglutinin Glycoproteins, Influenza Virus; Histocompatibility Antigens Class II; Immunoglobulin G; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Lipid Bilayers; Molecular Docking Simulation; Molecular Dynamics Simulation; Peptides; Phosphatidylcholines; Rabbits | 2015 |
Geometrical effects of phospholipid olefinic bonds on the structure and dynamics of membranes: A molecular dynamics study.
Topics: Acylation; Diffusion; Dimyristoylphosphatidylcholine; Lipid Bilayers; Membrane Microdomains; Molecular Dynamics Simulation; Molecular Structure; Oleic Acids; Phosphatidylcholines; Static Electricity; Structure-Activity Relationship | 2015 |
Fusion of raft-like lipid bilayers operated by a membranotropic domain of the HSV-type I glycoprotein gH occurs through a cholesterol-dependent mechanism.
Topics: Cholesterol; Glycoproteins; Lipid Bilayers; Molecular Dynamics Simulation; Peptides; Phosphatidylcholines; Protein Structure, Tertiary; Sphingomyelins; Viral Envelope Proteins; Viral Proteins | 2015 |
Inhibition of cancer cell proliferation and breast tumor targeting of pHLIP-monomethyl auristatin E conjugates.
Topics: Aminobenzoates; Animals; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Chemistry, Pharmaceutical; Circular Dichroism; Drug Delivery Systems; Female; HeLa Cells; Humans; Hydrogen-Ion Concentration; Membrane Proteins; Mice; Neoplasm Transplantation; Oligopeptides; Peptides; Phosphatidylcholines; Spectrometry, Fluorescence; Triple Negative Breast Neoplasms; Tryptophan | 2015 |
Structure and membrane interactions of chionodracine, a piscidin-like antimicrobial peptide from the icefish Chionodraco hamatus.
Topics: Amino Acid Sequence; Animals; Anti-Infective Agents; Antimicrobial Cationic Peptides; Cell Membrane; Cell Membrane Permeability; Escherichia coli; Fluoresceins; Fluorescence; Kinetics; Magnetic Resonance Spectroscopy; Micelles; Microbial Sensitivity Tests; Molecular Sequence Data; Perciformes; Phosphatidylcholines; Phosphatidylglycerols; Potassium Iodide; Psychrobacter; Temperature | 2015 |
A fluorinated detergent for membrane-protein applications.
Topics: Detergents; Halogenation; Liposomes; Membrane Proteins; Micelles; Phosphatidylcholines; Protein Refolding; Surface-Active Agents | 2015 |
Probing the Huntingtin 1-17 membrane anchor on a phospholipid bilayer by using all-atom simulations.
Topics: Amino Acid Sequence; Humans; Huntingtin Protein; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Sequence Data; Nerve Tissue Proteins; Peptide Fragments; Phosphatidylcholines; Protein Binding; Protein Structure, Tertiary | 2015 |
Molecular dynamics simulations on the interaction of the transmembrane NavAb channel with cholesterol and lipids in the membrane.
Topics: Bacterial Proteins; Cell Membrane; Cholesterol; Lipid Bilayers; Membrane Fluidity; Molecular Dynamics Simulation; Phosphatidylcholines; Sodium Channels | 2016 |
Cholesterol under oxidative stress-How lipid membranes sense oxidation as cholesterol is being replaced by oxysterols.
Topics: Cell Membrane; Fluorescence Polarization; Hydroxycholesterols; Lipid Bilayers; Molecular Dynamics Simulation; Oxidative Stress; Phosphatidylcholines | 2015 |
Effects of cholesterol and saturated sphingolipids on acyl chain order in 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine bilayers--a comparative study with phase-selective fluorophores.
Topics: Cholesterol; Fatty Acids, Unsaturated; Fluorescent Dyes; Lipid Bilayers; Models, Molecular; Molecular Conformation; Phosphatidylcholines; Sphingolipids | 2015 |
Capsaicin interaction with TRPV1 channels in a lipid bilayer: molecular dynamics simulation.
Topics: Binding Sites; Capsaicin; Cytosol; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Structure, Secondary; Sensory System Agents; TRPV Cation Channels; Water | 2015 |
Distinguishing bicontinuous lipid cubic phases from isotropic membrane morphologies using (31)P solid-state NMR spectroscopy.
Topics: Deuterium; Lipids; Magnetic Resonance Spectroscopy; Membranes, Artificial; Micelles; Parainfluenza Virus 5; Phase Transition; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Phosphorus Radioisotopes; Scattering, Small Angle; Temperature; Viral Fusion Proteins; X-Ray Diffraction | 2015 |
Understanding Miltefosine-Membrane Interactions Using Molecular Dynamics Simulations.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antineoplastic Agents; Cholesterol; Kinetics; Lipid Bilayers; Membrane Microdomains; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphorylcholine; Thermodynamics; Water | 2015 |
Structure and dynamics of POPC bilayers in water solutions of room temperature ionic liquids.
Topics: Anions; Cations; Chlorides; Diffusion; Hydrogen Bonding; Ionic Liquids; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Structure; Oxygen; Phosphates; Phosphatidylcholines; Salts; Static Electricity; Surface Properties; Temperature; Water | 2015 |
Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes.
Topics: Cell Line; Cell Membrane; Circular Dichroism; Humans; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phosphatidylcholines; Phosphatidylserines; Protein Folding; Protein Structure, Tertiary; Receptors, Prolactin; Receptors, Somatotropin; Recombinant Proteins; Scattering, Small Angle; Signal Transduction; Tyrosine; X-Ray Diffraction | 2015 |
A phosphatidylinositol-4-phosphate powered exchange mechanism to create a lipid gradient between membranes.
Topics: HeLa Cells; Humans; Lipid Metabolism; Liposomes; Lysine; Membrane Proteins; Oleic Acids; Phosphatidylcholines; Phosphatidylinositol Phosphates; Phosphatidylinositols; Receptors, Steroid; Saccharomyces cerevisiae Proteins; Sphingomyelins; Succinates | 2015 |
Nanoparticle-lipid bilayer interactions studied with lipid bilayer arrays.
Topics: Animals; Blood Proteins; Cattle; Cholesterol; Lipid Bilayers; Microarray Analysis; Nanoparticles; Osmolar Concentration; Phosphatidylcholines; Phosphatidylethanolamines | 2015 |
Impact of lipid oxidization on biophysical properties of model cell membranes.
Topics: Cell Membrane; Hydrodynamics; Kinetics; Lipid Bilayers; Models, Biological; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Phosphorylcholine; Unilamellar Liposomes | 2015 |
Substrate recognition mechanism of Streptomyces phospholipase D and enzymatic measurement of plasmalogen.
Topics: Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Liposomes; Lysophosphatidylcholines; Lysophospholipase; Micelles; Octoxynol; Phosphatidylcholines; Phospholipase D; Phospholipids; Plasmalogens; Streptomyces; Substrate Specificity; Temperature | 2015 |
Oligomers of Parkinson's Disease-Related α-Synuclein Mutants Have Similar Structures but Distinctive Membrane Permeabilization Properties.
Topics: alpha-Synuclein; Cell Membrane Permeability; Fluoresceins; Humans; Membranes, Artificial; Multiprotein Complexes; Mutation, Missense; Parkinson Disease; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Protein Binding; Scattering, Small Angle; X-Ray Diffraction | 2015 |
An early folding contact between Phe19 and Leu34 is critical for amyloid-β oligomer toxicity.
Topics: Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Membranes, Artificial; Mutation; Neurons; Peptide Fragments; Phosphatidylcholines; Phosphatidylglycerols; Protein Folding; Rats, Wistar; Unilamellar Liposomes | 2015 |
Chloride transport activities of trans- and cis-amide-linked bisureas.
Topics: Amides; Chlorides; Isomerism; Phosphatidylcholines; Urea | 2015 |
The influence of cholesterol precursor--desmosterol--on artificial lipid membranes.
Topics: Cholesterol; Desmosterol; Lipid Bilayers; Membranes, Artificial; Molecular Structure; Phosphatidylcholines; Sphingomyelins; Structure-Activity Relationship | 2015 |
Lamellar sheet exfoliation of single lipid vesicles by a membrane-active peptide.
Topics: Amino Acid Sequence; Biotinylation; Dynamic Light Scattering; Fluoresceins; Kinetics; Liposomes; Microscopy, Fluorescence; Models, Chemical; Nanostructures; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Protein Binding; Rhodamines; Solubility | 2015 |
Ubiquinone-10 alters mechanical properties and increases stability of phospholipid membranes.
Topics: Hydrophobic and Hydrophilic Interactions; Liposomes; Membrane Fluidity; Phosphatidylcholines; Porosity; Surface Properties; Tensile Strength; Ubiquinone; Viscosity | 2015 |
MARTINI Coarse-Grained Models of Polyethylene and Polypropylene.
Topics: Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Molecular Dynamics Simulation; Phosphatidylcholines; Polyethylene; Polypropylenes; Solvents | 2015 |
Interaction of β(3) /β(2) -peptides, consisting of Val-Ala-Leu segments, with POPC giant unilamellar vesicles (GUVs) and white blood cancer cells (U937)--a new type of cell-penetrating peptides, and a surprising chain-length dependence of their vesicle- a
Topics: Cell Death; Cell-Penetrating Peptides; Flow Cytometry; Humans; Lymphoma, Large B-Cell, Diffuse; Models, Molecular; Molecular Structure; Oligopeptides; Phosphatidylcholines; U937 Cells; Unilamellar Liposomes | 2015 |
Thermal transitions in serum amyloid A in solution and on the lipid: implications for structure and stability of acute-phase HDL.
Topics: Acute-Phase Reaction; Animals; Dimyristoylphosphatidylcholine; Humans; Lipoproteins, HDL; Mice; Phosphatidylcholines; Protein Denaturation; Protein Folding; Protein Stability; Serum Amyloid A Protein; Solutions; Temperature | 2015 |
Antimicrobial peptide dendrimer interacts with phosphocholine membranes in a fluidity dependent manner: A neutron reflection study combined with molecular dynamics simulations.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antimicrobial Cationic Peptides; Computer Simulation; Dendrimers; Lipid Bilayers; Membrane Fluidity; Models, Chemical; Molecular Conformation; Molecular Dynamics Simulation; Neutron Diffraction; Phosphatidylcholines | 2015 |
Effects of imidazolium-based ionic surfactants on the size and dynamics of phosphatidylcholine bilayers with saturated and unsaturated chains.
Topics: Borates; Dimyristoylphosphatidylcholine; Imidazoles; Ionic Liquids; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Solvents; Surface-Active Agents; Thermodynamics | 2015 |
Behaviour of NBD-head group labelled phosphatidylethanolamines in POPC bilayers: a molecular dynamics study.
Topics: Azoles; Hydrogen Bonding; Lipid Bilayers; Molecular Conformation; Molecular Dynamics Simulation; Nitrobenzenes; Phosphatidylcholines; Phosphatidylethanolamines; Static Electricity | 2015 |
Surface Density-Induced Pleating of a Lipid Monolayer Drives Nascent High-Density Lipoprotein Assembly.
Topics: ATP Binding Cassette Transporter 1; Cell Membrane Structures; Cholesterol; Lipid Bilayers; Lipoproteins, HDL; Molecular Dynamics Simulation; Phosphatidylcholines | 2015 |
Bacteria May Cope Differently from Similar Membrane Damage Caused by the Australian Tree Frog Antimicrobial Peptide Maculatin 1.1.
Topics: Amphibian Proteins; Animals; Antimicrobial Cationic Peptides; Anura; Cardiolipins; Cell Membrane; Cholesterol; Dose-Response Relationship, Drug; Erythrocytes; Escherichia coli; Hemolysis; Humans; Liposomes; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Species Specificity; Sphingomyelins; Staphylococcus aureus | 2015 |
Self-reproducing catalyst drives repeated phospholipid synthesis and membrane growth.
Topics: Catalysis; Cell Membrane; Copper; Cycloaddition Reaction; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Lipids; Membranes, Artificial; Microscopy, Confocal; Microscopy, Electron, Transmission; Models, Chemical; Molecular Structure; Phosphatidylcholines; Phospholipids; Time-Lapse Imaging; Triazoles; Unilamellar Liposomes | 2015 |
Properties of ultrathin cholesterol and phospholipid layers surrounding silicon-carbide nanotube: MD simulations.
Topics: Carbon Compounds, Inorganic; Cholesterol; Kinetics; Molecular Dynamics Simulation; Nanotubes; Phosphatidylcholines; Silicon Compounds; Temperature; Thermodynamics; Water | 2015 |
The effect of phospholipid composition of reconstituted HDL on its cholesterol efflux and anti-inflammatory properties.
Topics: Animals; Apolipoprotein A-I; Atherosclerosis; Cholesterol; Humans; Inflammation; Lipoproteins, HDL; Mice; Peptides; Phosphatidylcholines; Phospholipids; Rats; Sphingomyelins | 2015 |
Liposomes as nanoreactors for the photochemical synthesis of gold nanoparticles.
Topics: Gold; Gold Compounds; Light; Liposomes; Metal Nanoparticles; Microscopy, Electron, Transmission; Particle Size; Phosphatidylcholines; Photochemistry; Scattering, Radiation; Solvents; Time Factors; Ultraviolet Rays; Water | 2015 |
PET/CT Based In Vivo Evaluation of 64Cu Labelled Nanodiscs in Tumor Bearing Mice.
Topics: Animals; Cell Line, Tumor; Copper Radioisotopes; Disease Models, Animal; Heterocyclic Compounds, 1-Ring; Heterografts; Humans; Mice; Nanostructures; Neoplasms; Particle Size; Phosphatidylcholines; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution; Tomography, X-Ray Computed | 2015 |
Neutron Scattering Studies of the Effects of Formulating Amphotericin B with Cholesteryl Sulfate on the Drug's Interactions with Phospholipid and Phospholipid-Sterol Membranes.
Topics: Amphotericin B; Cholesterol Esters; Membranes, Artificial; Phosphatidylcholines; Phospholipids | 2015 |
Shape Transformations of Lipid Vesicles by Insertion of Bulky-Head Lipids.
Topics: Micelles; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Polyethylene Glycols; Thermodynamics; Unilamellar Liposomes | 2015 |
Coarse-grain molecular dynamics study of fullerene transport across a cell membrane.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cell Membrane; Fullerenes; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Temperature | 2015 |
Residue-specific structures and membrane locations of pH-low insertion peptide by solid-state nuclear magnetic resonance.
Topics: Hydrogen-Ion Concentration; Isotope Labeling; Magnetic Resonance Spectroscopy; Membrane Proteins; Phosphatidylcholines | 2015 |
Small-angle X-ray scattering of the cholesterol incorporation into human ApoA1-POPC discoidal particles.
Topics: Apolipoprotein A-I; Cholesterol; Humans; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Models, Molecular; Phosphates; Phosphatidylcholines; Scattering, Small Angle; Solutions; X-Ray Diffraction | 2015 |
A computer simulation approach to quantify the true area and true area compressibility modulus of biological membranes.
Topics: Biomechanical Phenomena; Computer Simulation; Lipid Bilayers; Models, Biological; Phosphatidylcholines; Thermodynamics | 2015 |
Physical properties of the hybrid lipid POPC on micrometer-sized domains in mixed lipid membranes.
Topics: Chemistry, Physical; Microscopy, Confocal; Microscopy, Fluorescence; Particle Size; Phosphatidylcholines; Surface Properties | 2015 |
Interaction of Cytotoxic and Cytoprotective Bile Acids with Model Membranes: Influence of the Membrane Composition.
Topics: Cholesterol; Deoxycholic Acid; Liposomes; Models, Molecular; Phosphatidylcholines; Sphingomyelins; Ursodeoxycholic Acid | 2015 |
Reconstitution of Functionalized Transmembrane Domains of Receptor Proteins into Biomimetic Membranes.
Topics: CD4 Antigens; ErbB Receptors; Humans; Lipid Bilayers; Phosphatidylcholines; Protein Structure, Tertiary | 2015 |
Hydrodynamic and Membrane Binding Properties of Purified Rous Sarcoma Virus Gag Protein.
Topics: Cell Membrane; Cholesterol; Escherichia coli; Gene Expression; Gene Products, gag; HIV-1; Hydrodynamics; Lipid Bilayers; Osmolar Concentration; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositol 4,5-Diphosphate; Protein Binding; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Rous sarcoma virus; Virion | 2015 |
Capsaicin Fluidifies the Membrane and Localizes Itself near the Lipid-Water Interface.
Topics: Calorimetry, Differential Scanning; Capsaicin; Humans; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Chemical; Phosphatidylcholines; Phosphorus Isotopes; Tritium; Water; X-Ray Diffraction | 2015 |
Influence of the sterol aliphatic side chain on membrane properties: a molecular dynamics study.
Topics: Lipid Bilayers; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines; Sterols | 2015 |
Preserved transmembrane protein mobility in polymer-supported lipid bilayers derived from cell membranes.
Topics: Amino Acid Sequence; Aspartic Acid Endopeptidases; Cell Line; Cell Membrane; Dimethylpolysiloxanes; Glass; Lipid Bilayers; Membrane Proteins; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Movement; Phosphatidylcholines; Polyethylene Glycols; Surface Properties | 2015 |
Viscoelastic deformation of lipid bilayer vesicles.
Topics: Elasticity; Lipid Bilayers; Optical Tweezers; Phosphatidylcholines; Unilamellar Liposomes; Viscosity | 2015 |
Expression, purification, refolding, and enzymatic characterization of two secretory phospholipases A₂ from Neurospora crassa.
Topics: Amino Acid Sequence; Escherichia coli; Hydrogen-Ion Concentration; Micelles; Molecular Sequence Data; Neurospora crassa; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A2, Secretory; Protein Refolding; Recombinant Proteins; Sequence Alignment | 2015 |
Lipid modulation of early G protein-coupled receptor signalling events.
Topics: Animals; Brain Chemistry; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Ligands; Lipid Bilayers; Lipids; Membrane Lipids; Nanotechnology; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Protein Binding; Receptors, G-Protein-Coupled; Receptors, Neurotensin; Signal Transduction; Swine; Temperature; Thermodynamics | 2015 |
Oleuropein aglycone in lipid bilayer membranes. A molecular dynamics study.
Topics: Cholesterol; Iridoid Glucosides; Iridoids; Kinetics; Lipid Bilayers; Membrane Lipids; Molecular Dynamics Simulation; Molecular Structure; Phosphatidylcholines; Phosphatidylglycerols; Water | 2015 |
Hematin loses its membranotropic activity upon oligomerization into malaria pigment.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Cattle; Cell Membrane; Dimerization; Erythrocytes; Heme; Hemeproteins; Hemin; Hemoglobins; Hydrogen-Ion Concentration; Kinetics; Lipid Bilayers; Microscopy, Atomic Force; Molecular Structure; Phosphatidylcholines; Plasmodium falciparum; Swine | 2015 |
Enzyme-coupled assays for flip-flop of acyl-Coenzyme A in liposomes.
Topics: Acyl Coenzyme A; Alkaline Phosphatase; Biological Transport; Chemistry Techniques, Analytical; Glycerol-3-Phosphate O-Acyltransferase; Glycerophosphates; Lipid Bilayers; Liposomes; Phosphatidylcholines; Phosphatidylethanolamines; Reproducibility of Results; Serum Albumin, Bovine; Unilamellar Liposomes | 2015 |
Effect of Supporting Polyelectrolyte Multilayers and Deposition Conditions on the Formation of 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine/1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine Lipid Bilayers.
Topics: Electrolytes; Hydrogen-Ion Concentration; Kinetics; Lipid Bilayers; Microscopy, Atomic Force; Particle Size; Phosphatidylcholines; Phosphatidylethanolamines; Polymers; Quartz Crystal Microbalance Techniques; Sodium Chloride; Surface Properties | 2015 |
Interaction studies reveal specific recognition of an anti-inflammatory polyphosphorhydrazone dendrimer by human monocytes.
Topics: Anti-Inflammatory Agents; Calorimetry, Differential Scanning; Cells, Cultured; Dendrimers; Humans; Lipid Bilayers; Microscopy, Confocal; Molecular Dynamics Simulation; Monocytes; Phosphatidylcholines; Phosphorus | 2015 |
New Insights into the Growth and Transformation of Vesicles: A Free-Flow Electrophoresis Study.
Topics: Computer Simulation; Cryoelectron Microscopy; Liposomes; Membrane Fluidity; Micelles; Models, Chemical; Phosphatidylcholines; Water | 2015 |
Effects of Lys to Glu mutations in GsMTx4 on membrane binding, peptide orientation, and self-association propensity, as analyzed by molecular dynamics simulations.
Topics: Cell Membrane; Glutamic Acid; Intercellular Signaling Peptides and Proteins; Kinetics; Lipid Bilayers; Lysine; Membrane Lipids; Molecular Dynamics Simulation; Mutation, Missense; Peptides; Phosphatidylcholines; Protein Binding; Spider Venoms; Thermodynamics | 2015 |
Introducing a fluorescence-based standard to quantify protein partitioning into membranes.
Topics: Algorithms; Cell Membrane; Diffusion; Fluorescence; Green Fluorescent Proteins; Kinetics; Lipid Bilayers; Membrane Proteins; Microscopy, Confocal; Models, Chemical; Models, Molecular; Phosphatidylcholines; Spectrometry, Fluorescence; Unilamellar Liposomes | 2015 |
A Parameterization of Cholesterol for Mixed Lipid Bilayer Simulation within the Amber Lipid14 Force Field.
Topics: Alkanes; Cholesterol; Dimyristoylphosphatidylcholine; Glycerylphosphorylcholine; Lipid Bilayers; Molecular Dynamics Simulation; Naphthalenes; Neutron Diffraction; Phosphatidylcholines; Temperature; X-Ray Diffraction | 2015 |
Pore hydration states of KcsA potassium channels in membranes.
Topics: Bacterial Proteins; Cell Membrane; Escherichia coli; Gene Expression; Influenza A virus; Ion Channel Gating; Ion Transport; Lipid Bilayers; Models, Molecular; Phosphatidylcholines; Phosphatidylglycerols; Potassium; Potassium Channel Blockers; Potassium Channels; Protein Conformation; Protein Multimerization; Protons; Quaternary Ammonium Compounds; Recombinant Proteins; Streptomyces lividans; Viral Matrix Proteins; Water | 2015 |
Extension of a protein docking algorithm to membranes and applications to amyloid precursor protein dimerization.
Topics: Algorithms; Amyloid beta-Protein Precursor; Cell Membrane; Entropy; Lipid Bilayers; Micelles; Molecular Docking Simulation; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Multimerization | 2015 |
Interaction of NBD-labelled fatty amines with liquid-ordered membranes: a combined molecular dynamics simulation and fluorescence spectroscopy study.
Topics: Amines; Azoles; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Structure; Nitrobenzenes; Phosphatidylcholines; Spectrometry, Fluorescence; Sphingomyelins | 2015 |
Oxidative Degradation of the Monolayer of 1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphocholine (POPC) in Low-Level Ozone.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Molecular Conformation; Oxidation-Reduction; Ozone; Phosphatidylcholines | 2015 |
Electric polarizability of lipid bilayers: The influence of the structure.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Electricity; Lipid Bilayers; Molecular Structure; Phosphatidylcholines | 2015 |
The Effect of Membrane Lipid Composition on the Formation of Lipid Ultrananodomains.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Brain; Cholesterol; Fluorescence Resonance Energy Transfer; Membrane Microdomains; Membranes, Artificial; Nanostructures; Phosphatidylcholines; Sphingomyelins; Swine; Temperature | 2015 |
Influence of Hydroxylation, Chain Length, and Chain Unsaturation on Bilayer Properties of Ceramides.
Topics: Anisotropy; Ceramides; Cholesterol; Fluorescence; Hydroxylation; Lipid Bilayers; Molecular Structure; Phosphatidylcholines; Sphingomyelins; Temperature; Thermography | 2015 |
Can Specific Protein-Lipid Interactions Stabilize an Active State of the Beta 2 Adrenergic Receptor?
Topics: Binding Sites; Carbon; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Mutation; Oxygen; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Protein Stability; Receptors, Adrenergic, beta-2 | 2015 |
Effect of superparamagnetic iron oxide nanoparticles on fluidity and phase transition of phosphatidylcholine liposomal membranes.
Topics: Calorimetry, Differential Scanning; Dextrans; Fluorescence Polarization; Lipid Bilayers; Liposomes; Magnetite Nanoparticles; Membrane Fluidity; Nanoparticles; Phase Transition; Phosphatidylcholines; Silicon Dioxide | 2015 |
Branched phospholipids render lipid vesicles more susceptible to membrane-active peptides.
Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bacterial Proteins; Cell Membrane; Drug Compounding; Drug Liberation; Drug Resistance, Bacterial; Fluoresceins; Fluorescent Dyes; Hemolysin Proteins; Kinetics; Lipid Bilayers; Liposomes; Lysophosphatidylcholines; Myristic Acids; Phase Transition; Phosphatidylcholines; Phosphatidylglycerols; Staphylococcus; Staphylococcus aureus | 2016 |
The biophysical properties of ethanolamine plasmalogens revealed by atomistic molecular dynamics simulations.
Topics: Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Plasmalogens; Structure-Activity Relationship | 2016 |
Molecular dynamics of water and monovalent-ions transportation mechanisms of pentameric sarcolipin.
Topics: Humans; Ion Transport; Lipid Bilayers; Molecular Dynamics Simulation; Muscle Proteins; Permeability; Phosphatidylcholines; Potassium; Protein Conformation; Protein Multimerization; Proteolipids; Sodium; Water | 2016 |
Sub-ten-nanometer heterogeneity of solid supported lipid membranes determined by solution atomic force microscopy.
Topics: Cholesterol; Membranes, Artificial; Microscopy, Atomic Force; Models, Chemical; Phosphatidylcholines; Sphingomyelins; Surface Properties | 2016 |
Cholesterol-Dependent Conformational Exchange of the C-Terminal Domain of the Influenza A M2 Protein.
Topics: Cholesterol; Influenza A virus; Membranes, Artificial; Models, Chemical; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary; Protein Structure, Tertiary; Viral Matrix Proteins | 2015 |
Computational Lipidomics with insane: A Versatile Tool for Generating Custom Membranes for Molecular Simulations.
Topics: Gangliosides; Lipid Bilayers; Membrane Proteins; Molecular Dynamics Simulation; Phosphatidylcholines | 2015 |
High-Throughput Simulations of Dimer and Trimer Assembly of Membrane Proteins. The DAFT Approach.
Topics: Dimerization; Glycophorins; Lipid Bilayers; Membrane Proteins; Molecular Dynamics Simulation; Mutation; Peptides; Phosphatidylcholines; Protein Multimerization; Rhodopsin | 2015 |
Two-Dimensional Potentials of Mean Force of Nile Red in Intact and Damaged Model Bilayers. Application to Calculations of Fluorescence Spectra.
Topics: Algorithms; Dimyristoylphosphatidylcholine; Lipid Bilayers; Molecular Dynamics Simulation; Oxazines; Phosphatidylcholines; Quantum Theory; Spectrometry, Fluorescence | 2016 |
Direct-Space Corrections Enable Fast and Accurate Lorentz-Berthelot Combination Rule Lennard-Jones Lattice Summation.
Topics: Algorithms; Dimyristoylphosphatidylcholine; Lipid Bilayers; Phosphatidylcholines; Static Electricity; Water | 2015 |
Communication: Probing anomalous diffusion in frequency space.
Topics: Diffusion; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines | 2015 |
Alteration of lipid membrane structure and dynamics by diacylglycerols with unsaturated chains.
Topics: Diglycerides; Lipid Bilayers; Models, Chemical; Phosphatidylcholines | 2016 |
The modified fluorescence based vesicle fluctuation spectroscopy technique for determination of lipid bilayer bending properties.
Topics: Fluorescent Dyes; Lipid Bilayers; Phosphatidylcholines; Spectrometry, Fluorescence | 2016 |
Surface interactions, thermodynamics and topography of binary monolayers of Insulin with dipalmitoylphosphatidylcholine and 1-palmitoyl-2-oleoylphosphatidylcholine at the air/water interface.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Air; Insulin; Particle Size; Phosphatidylcholines; Surface Properties; Thermodynamics; Water | 2016 |
Small-angle scattering determination of the shape and localization of human cytochrome P450 embedded in a phospholipid nanodisc environment.
Topics: Amino Acid Motifs; Catalytic Domain; Cytochrome P-450 CYP3A; Drug Compounding; Gene Expression; Humans; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Nanostructures; Phosphatidylcholines; Protein Structure, Secondary; Recombinant Proteins; Scattering, Small Angle; X-Ray Diffraction | 2015 |
Binding Orientations and Lipid Interactions of Human Amylin at Zwitterionic and Anionic Lipid Bilayers.
Topics: Humans; Islet Amyloid Polypeptide; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding | 2016 |
Translocation of 5' mRNA cap analogue--peptide conjugates across the membranes of giant unilamellar vesicles.
Topics: Cell-Penetrating Peptides; Microscopy, Fluorescence; Phosphatidylcholines; RNA Caps; Unilamellar Liposomes | 2016 |
Coarse-grained bond and angle distributions from atomistic simulations: On the systematic parameterisation of lipid models.
Topics: Lipid Bilayers; Models, Chemical; Molecular Dynamics Simulation; Phosphatidylcholines; Solutions; Thermodynamics; Water | 2016 |
Phosphatidylethanolamine Is a Key Regulator of Membrane Fluidity in Eukaryotic Cells.
Topics: Animals; Cell Membrane; Cholesterol; Fluorescence Polarization; HEK293 Cells; Humans; Lipid Bilayers; Liposomes; Membrane Fluidity; Models, Biological; Particle Size; Phosphatidylcholines; Phosphatidylethanolamines; Sf9 Cells; Species Specificity; Spodoptera; Temperature | 2016 |
Efficient, non-toxic anion transport by synthetic carriers in cells and epithelia.
Topics: Animals; Anions; Bacterial Proteins; Cell Membrane; Cell Proliferation; Cell Survival; Chlorine; Cyclohexanes; Cystic Fibrosis Transmembrane Conductance Regulator; Dogs; Drug Carriers; Drug Design; Electrophysiological Phenomena; Epithelial Cells; HeLa Cells; Humans; Hydrogen Bonding; Ion Transport; Luminescent Proteins; Madin Darby Canine Kidney Cells; Microscopy, Fluorescence; Molecular Structure; Naphthalenes; Phosphatidylcholines; Rats, Inbred F344; Steroids | 2016 |
Guanidinium Pairing Facilitates Membrane Translocation.
Topics: Guanidine; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Quantum Theory; Thermodynamics; Water | 2016 |
The Rheological Properties of Lipid Monolayers Modulate the Incorporation of l-Ascorbic Acid Alkyl Esters.
Topics: Alkylation; Ascorbic Acid; Biological Transport; Biomimetic Materials; Cholesterol; Epidermis; Esters; Humans; Kinetics; Lipid Bilayers; Permeability; Phase Transition; Phosphatidylcholines; Pressure; Rheology; Surface Properties; Water | 2016 |
Unexpected products of the hypochlorous acid-induced oxidation of oleic acid: A study using high performance thin-layer chromatography-electrospray ionization mass spectrometry.
Topics: Chlorohydrins; Chromatography, Thin Layer; Dimerization; Esters; Halogenation; Hypochlorous Acid; Isomerism; Oleic Acid; Oxidation-Reduction; Phosphatidylcholines; Spectrometry, Mass, Electrospray Ionization | 2016 |
Reversing the peptide sequence impacts on molecular surface behaviour.
Topics: Amino Acid Sequence; Biological Transport; Hydrophobic and Hydrophilic Interactions; Molecular Sequence Data; Peptides; Permeability; Phosphatidylcholines; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Static Electricity; Structure-Activity Relationship; Unilamellar Liposomes | 2016 |
Hydrogen-Bonding Structure at Zwitterionic Lipid/Water Interface.
Topics: Hydrogen Bonding; Molecular Dynamics Simulation; Phosphatidylcholines; Spectrum Analysis; Water | 2016 |
On the application of the MARTINI coarse-grained model to immersion of a protein in a phospholipid bilayer.
Topics: Cytochrome P-450 Enzyme System; Diffusion; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Membrane Proteins; Molecular Dynamics Simulation; Phosphatidylcholines | 2015 |
Superresolution and Fluorescence Dynamics Evidence Reveal That Intact Liposomes Do Not Cross the Human Skin Barrier.
Topics: Administration, Cutaneous; Cryoelectron Microscopy; Diffusion; Drug Carriers; Fluorescence; Fluorescent Dyes; Humans; Liposomes; Microscopy, Confocal; Microscopy, Fluorescence; Permeability; Phosphatidylcholines; Skin; Skin Absorption | 2016 |
Effective lipid-detergent system for study of membrane active peptides in fluid liposomes.
Topics: Anti-Bacterial Agents; Cell Membrane; Detergents; Dynamic Light Scattering; Glycine max; Gramicidin; Liposomes; Membrane Fluidity; Membrane Potentials; Octoxynol; Phosphatidylcholines | 2016 |
The impact of physiological crowding on the diffusivity of membrane bound proteins.
Topics: Adaptor Proteins, Vesicular Transport; Diffusion; Histidine; Kinetics; Lysine; Molecular Weight; Oleic Acids; Oligopeptides; Phosphatidylcholines; Protein Binding; Receptors, Transferrin; Succinates; Transferrin; Ubiquitin; Unilamellar Liposomes | 2016 |
The inhibition of glycerol permeation through aquaglyceroporin-3 induced by mercury(II): A molecular dynamics study.
Topics: Aquaporin 3; Aquaporins; Binding Sites; Biological Transport; Cations, Divalent; Cell Membrane Permeability; Escherichia coli; Escherichia coli Proteins; Glycerol; Humans; Membranes, Artificial; Mercury; Molecular Dynamics Simulation; Phosphatidylcholines; Plasmodium falciparum; Protein Binding; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Structural Homology, Protein; Water | 2016 |
Formation of stable nanodiscs by bihelical apolipoprotein A-I mimetic peptide.
Topics: Amino Acid Sequence; Apolipoprotein A-I; Cholic Acid; Dynamic Light Scattering; Humans; Molecular Mimicry; Molecular Sequence Data; Nanostructures; Particle Size; Peptide Fragments; Phosphatidylcholines; Protein Stability; Protein Structure, Secondary | 2016 |
Phospholipase A2-Induced Remodeling Processes on Liquid-Ordered/Liquid-Disordered Membranes Containing Docosahexaenoic or Oleic Acid: A Comparison Study.
Topics: Cell Membrane; Cholesterol; Docosahexaenoic Acids; Elastic Modulus; Oleic Acid; Phosphatidylcholines; Phospholipases A2; Sphingomyelins | 2016 |
Membrane Protein Mobility and Orientation Preserved in Supported Bilayers Created Directly from Cell Plasma Membrane Blebs.
Topics: Cell Membrane; Diffusion; Dithiothreitol; Formaldehyde; GPI-Linked Proteins; Green Fluorescent Proteins; HeLa Cells; Humans; Lipid Bilayers; Liposomes; Luminescent Proteins; Microscopy, Fluorescence; Phosphatidylcholines; Receptors, Purinergic P2X2 | 2016 |
Membrane Interactions, Ligand-Dependent Dynamics, and Stability of Cytochrome P4503A4 in Lipid Nanodiscs.
Topics: Apolipoprotein A-I; Calorimetry, Differential Scanning; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Deuterium Exchange Measurement; Enzyme Stability; Humans; Ketoconazole; Ligands; Lipid Bilayers; Membrane Microdomains; Membrane Proteins; Models, Molecular; Peptide Fragments; Phosphatidylcholines; Protein Conformation; Protein Engineering; Protein Structure, Tertiary; Protein Unfolding; Recombinant Fusion Proteins; Recombinant Proteins | 2016 |
Interaction of the Alzheimer Aβ(25-35) peptide segment with model membranes.
Topics: Amyloid beta-Peptides; Cholesterol; Circular Dichroism; Hydrophobic and Hydrophilic Interactions; Liposomes; Membrane Lipids; Peptide Fragments; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Sphingomyelins; Thermodynamics; Unilamellar Liposomes | 2016 |
Topologically Diverse Human Membrane Proteins Partition to Liquid-Disordered Domains in Phase-Separated Lipid Vesicles.
Topics: Amyloid beta-Protein Precursor; Caveolin 3; Cholesterol; Fluorescent Dyes; Humans; Hydrophobic and Hydrophilic Interactions; Membrane Microdomains; Microscopy, Confocal; Microscopy, Fluorescence; Models, Molecular; Myelin Proteins; Peptide Fragments; Phosphatidylcholines; Phosphatidylethanolamines; Protein Conformation; Protein Interaction Domains and Motifs; Recombinant Proteins; Rhodamines; Sphingomyelins; Unilamellar Liposomes | 2016 |
TRPV1 channel as a target for cancer therapy using CNT-based drug delivery systems.
Topics: Animals; Antineoplastic Agents; Cell Membrane; Doxorubicin; Drug Carriers; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Targeted Therapy; Nanotubes, Carbon; Permeability; Phosphatidylcholines; Protein Conformation; Rats; TRPV Cation Channels | 2016 |
Membrane topologies of the PGLa antimicrobial peptide and a transmembrane anchor sequence by Dynamic Nuclear Polarization/solid-state NMR spectroscopy.
Topics: Amino Acid Sequence; Anti-Infective Agents; Antimicrobial Cationic Peptides; Cold Temperature; Dimyristoylphosphatidylcholine; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylglycerols | 2016 |
Properties of lipid electropores I: Molecular dynamics simulations of stabilized pores by constant charge imbalance.
Topics: Electroporation; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines | 2016 |
Graphene Oxide and Lipid Membranes: Size-Dependent Interactions.
Topics: Choline; Graphite; Liposomes; Palmitic Acids; Particle Size; Phosphatidylcholines; Quartz Crystal Microbalance Techniques; Silicon Dioxide | 2016 |
Encapsulation of Living Cells within Giant Phospholipid Liposomes Formed by the Inverse-Emulsion Technique.
Topics: Emulsions; Escherichia coli; Fluorescent Dyes; Liposomes; Microscopy, Fluorescence; Peptide Hydrolases; Phosphatidylcholines; Time-Lapse Imaging | 2016 |
Amyloid-β(25-35) peptides aggregate into cross-β sheets in unsaturated anionic lipid membranes at high peptide concentrations.
Topics: Amyloid beta-Peptides; Anions; Lipid Bilayers; Microscopy; Monte Carlo Method; Peptide Fragments; Phosphatidylcholines; Protein Structure, Secondary; Unithiol; X-Ray Diffraction | 2016 |
The Lipid Bilayer Provides a Site for Cortisone Crystallization at High Cortisone Concentrations.
Topics: Cortisone; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines | 2016 |
Using ApoE Nanolipoprotein Particles To Analyze SNARE-Induced Fusion Pores.
Topics: Apolipoproteins E; Calcium; Cholesterol; Dextrans; Dimyristoylphosphatidylcholine; Dithionite; Fluorescent Dyes; Liposomes; Membrane Fusion; Nanoparticles; Particle Size; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphatidylserines; Synaptosomal-Associated Protein 25; Syntaxin 1; Vesicle-Associated Membrane Protein 2 | 2016 |
Association of Peripheral Membrane Proteins with Membranes: Free Energy of Binding of GRP1 PH Domain with Phosphatidylinositol Phosphate-Containing Model Bilayers.
Topics: Animals; Binding Sites; Humans; Lipid Bilayers; Mice; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylinositol Phosphates; Phosphatidylserines; Pleckstrin Homology Domains; Protein Binding; Receptors, Cytoplasmic and Nuclear; Thermodynamics | 2016 |
Reconstitution of Fusion Proteins in Supported Lipid Bilayers for the Study of Cell Surface Receptor-Ligand Interactions in Cell-Cell Contact.
Topics: Animals; Biomimetic Materials; Cell Adhesion; Cells, Cultured; Cerebral Cortex; Ephrin-A5; Female; Humans; Immunoglobulin Fc Fragments; Lipid Bilayers; Mice; Neurons; Patch-Clamp Techniques; Phosphatidylcholines; Rats, Wistar; Receptor, EphA5; Recombinant Fusion Proteins | 2016 |
Studying the effects of asymmetry on the bending rigidity of lipid membranes formed by microfluidics.
Topics: Biomechanical Phenomena; Equipment Design; Lab-On-A-Chip Devices; Membrane Fluidity; Membrane Lipids; Phosphatidylcholines; Unilamellar Liposomes | 2016 |
The adrenal specific toxicant mitotane directly interacts with lipid membranes and alters membrane properties depending on lipid composition.
Topics: Adrenal Glands; Ascorbic Acid; Biological Assay; Electron Spin Resonance Spectroscopy; Fluorescence; Lipid Bilayers; Lipids; Mitotane; Organ Specificity; Phosphatidylcholines; Phosphatidylethanolamines; Proton Magnetic Resonance Spectroscopy; Unilamellar Liposomes | 2016 |
Specific and Reversible DNA-Directed Self-Assembly of Modular Vesicle-Droplet Hybrid Materials.
Topics: Base Sequence; Biotin; DNA, Single-Stranded; Indicators and Reagents; Manufactured Materials; Membranes, Artificial; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; Streptavidin; Transition Temperature; Unilamellar Liposomes | 2016 |
A Critical Comparison of Biomembrane Force Fields: Structure and Dynamics of Model DMPC, POPC, and POPE Bilayers.
Topics: Dimyristoylphosphatidylcholine; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Structure; Phosphatidylcholines; Phosphatidylethanolamines | 2016 |
Structural and functional evaluation of the palindromic alanine-rich antimicrobial peptide Pa-MAP2.
Topics: Alanine; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Cell Survival; Chlorocebus aethiops; Cholesterol; Erythrocytes; Escherichia coli; Escherichia coli Infections; Flounder; Humans; Lipopolysaccharides; Mice; Molecular Dynamics Simulation; Molecular Sequence Data; Peptidomimetics; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Protein Structure, Secondary; Protein Structure, Tertiary; Survival Analysis; Unilamellar Liposomes; Vero Cells | 2016 |
The effects of chondroitin sulfate and serum albumin on the fibrillation of human islet amyloid polypeptide at phospholipid membranes.
Topics: Amyloid; Animals; Cattle; Chondroitin Sulfates; Humans; Islet Amyloid Polypeptide; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Serum Albumin, Bovine; Unilamellar Liposomes | 2016 |
Asymmetric dynamics of ion channel forming proteins - Hepatitis C virus (HCV) p7 bundles.
Topics: Amino Acid Sequence; Calcium; Cations, Divalent; Genotype; Hepacivirus; Ion Channels; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Protons; Thermodynamics; Viral Proteins | 2016 |
Pair interactions among ternary DPPC/POPC/cholesterol mixtures in liquid-ordered and liquid-disordered phases.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Membrane Microdomains; Molecular Dynamics Simulation; Phosphatidylcholines | 2016 |
Interactions of lauryl gallate with phospholipid components of biological membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Gallic Acid; Membrane Lipids; Microscopy, Polarization; Phosphatidylcholines; Phospholipids; Surface-Active Agents | 2016 |
Behavior of Bilayer Leaflets in Asymmetric Model Membranes: Atomistic Simulation Studies.
Topics: Cholesterol; Diffusion; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Pressure; Surface Tension | 2016 |
Enhanced Heat Stability of α-Chymotrypsin through Single-Enzyme Confinement in Attoliter Liposomes.
Topics: Aniline Compounds; Animals; Ascomycota; Cattle; Chymotrypsin; Endopeptidase K; Heating; Oligopeptides; Particle Size; Phosphatidylcholines; Protein Stability; Unilamellar Liposomes | 2016 |
Transformable DNA nanocarriers for plasma membrane targeted delivery of cytokine.
Topics: Cell Death; Cell Line, Tumor; Cell Membrane; Cytokines; DNA; Drug Carriers; Drug Delivery Systems; Humans; Hydrodynamics; Liposomes; Nanoparticles; Nickel; Particle Size; Phosphatidylcholines; Phospholipases A2; TNF-Related Apoptosis-Inducing Ligand | 2016 |
Protein-Backbone Thermodynamics across the Membrane Interface.
Topics: Lipid Bilayers; Models, Molecular; Phosphatidylcholines; Proteins; Solvents; Thermodynamics; Water | 2016 |
Effect of Headgroups on Small-Ion Permeability across Archaea-Inspired Tetraether Lipid Membranes.
Topics: Archaea; Diglycerides; Dynamic Light Scattering; Fluoresceins; Ions; Liposomes; Membrane Lipids; Phosphatidylcholines; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2016 |
Membrane permeabilizing action of amphidinol 3 and theonellamide A in raft-forming lipid mixtures.
Topics: Alkenes; Antifungal Agents; Cell Membrane Permeability; Cholesterol; Dinoflagellida; Fluoresceins; Lipid Bilayers; Liposomes; Membrane Lipids; Membrane Microdomains; Molecular Structure; Peptides, Cyclic; Phosphatidylcholines; Pyrans; Spectrometry, Fluorescence; Sphingomyelins | 2017 |
The impact of cell-penetrating peptides on membrane bilayer structure during binding and insertion.
Topics: Amino Acid Sequence; Biotinylation; Birefringence; Carrier Proteins; Cell-Penetrating Peptides; Dimyristoylphosphatidylcholine; Gels; Interferometry; Kinetics; Lipid Bilayers; Liposomes; Membrane Lipids; Models, Chemical; Peptide Fragments; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Structure-Activity Relationship | 2016 |
Quantifying the Relationship between Curvature and Electric Potential in Lipid Bilayers.
Topics: Electricity; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines | 2016 |
On the microscopic and mesoscopic perturbations of lipid bilayers upon interaction with the MPER domain of the HIV glycoprotein gp41.
Topics: Calorimetry, Differential Scanning; Cholesterol; Dynamic Light Scattering; Electron Spin Resonance Spectroscopy; HIV Envelope Protein gp41; Lipid Bilayers; Liposomes; Liquid Crystals; Membrane Fluidity; Membrane Lipids; Membrane Proteins; Peptide Fragments; Phosphatidylcholines; Protein Domains; Sphingomyelins | 2016 |
Unraveling the Composition and Behavior of Heterogeneous Lipid Nanodiscs by Mass Spectrometry.
Topics: Fourier Analysis; Gases; Lipid Bilayers; Mass Spectrometry; Nanostructures; Phosphatidylcholines; Phosphatidylglycerols | 2016 |
Effect of Stearylguanidinium-Modified POPC Vesicles on the Melting Behavior of tRNA Molecules.
Topics: Circular Dichroism; Guanidine; Lipid Bilayers; Membrane Fluidity; Nephelometry and Turbidimetry; Nucleic Acid Conformation; Nucleic Acid Denaturation; Phosphatidylcholines; RNA, Transfer; Transition Temperature | 2016 |
Acyl Chain Disorder and Azelaoyl Orientation in Lipid Membranes Containing Oxidized Lipids.
Topics: Lipid Bilayers; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Phosphatidylcholines; Phosphorylcholine | 2016 |
Experimental Determination of High-Order Bending Elastic Constants of Lipid Bilayers.
Topics: Dimyristoylphosphatidylcholine; Elasticity; Lipid Bilayers; Liposomes; Monte Carlo Method; Phosphatidylcholines; Scattering, Small Angle; Thermodynamics; X-Ray Diffraction | 2016 |
Release of Entropic Spring Reveals Conformational Coupling Mechanism in the ABC Transporter BtuCD-F.
Topics: Adenosine Triphosphate; ATP-Binding Cassette Transporters; Entropy; Escherichia coli; Escherichia coli Proteins; Lipid Bilayers; Molecular Dynamics Simulation; Mutation; Periplasmic Binding Proteins; Phosphatidylcholines; Protein Multimerization; Protein Stability; Stress, Mechanical; Water | 2016 |
Oligomerization of the Tetraspanin CD81 via the Flexibility of Its δ-Loop.
Topics: Cell Membrane; Elasticity; Gangliosides; Humans; Jurkat Cells; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Multimerization; Protein Structure, Secondary; Solvents; Tetraspanin 28 | 2016 |
Accelerated molecular dynamics simulations of the octopamine receptor using GPUs: discovery of an alternate agonist-binding position.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Benzoxazines; Computer Graphics; Hydrogen Bonding; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Promethazine; Propanolamines; Protein Binding; Receptors, Biogenic Amine; Structural Homology, Protein; Thermodynamics; Time Factors; User-Computer Interface | 2016 |
Exploring the Membrane Potential of Simple Dual-Membrane Systems as Models for Gap-Junction Channels.
Topics: Animals; Connexins; Gap Junctions; Hydrophobic and Hydrophilic Interactions; Ion Transport; Membrane Potentials; Membranes, Artificial; Models, Biological; Molecular Dynamics Simulation; Phosphatidylcholines; Static Electricity; Thermodynamics | 2016 |
Effect of Lauryl Gallate on Wetting Properties of Organized Thin Phospholipid Films on Mica.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Aluminum Silicates; Gallic Acid; Microscopy, Atomic Force; Phosphatidylcholines; Phospholipids; Surface Properties; Wettability | 2016 |
Effect of Saturated Very Long-Chain Fatty Acids on the Organization of Lipid Membranes: A Study Combining (2)H NMR Spectroscopy and Molecular Dynamics Simulations.
Topics: Fatty Acids; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Phosphatidylcholines; Temperature | 2016 |
Tris-ureas as transmembrane anion transporters.
Topics: Bicarbonates; Chlorides; Cholesterol; Lipid Bilayers; Membrane Transport Proteins; Nitrates; Phosphatidylcholines; Urea | 2016 |
Divergent Diffusion Coefficients in Simulations of Fluids and Lipid Membranes.
Topics: Diffusion; Hydrodynamics; Lipid Bilayers; Membrane Lipids; Molecular Dynamics Simulation; Phosphatidylcholines | 2016 |
Pushing the Envelope: Dengue Viral Membrane Coaxed into Shape by Molecular Simulations.
Topics: Binding Sites; Cryoelectron Microscopy; Dengue Virus; Hydrogen-Ion Concentration; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Static Electricity; Viral Envelope Proteins; Virion | 2016 |
Influence of oxidized lipids on palmitoyl-oleoyl-phosphatidylcholine organization, contribution of Langmuir monolayers and Langmuir-Blodgett films.
Topics: Microscopy, Atomic Force; Molecular Conformation; Oxidation-Reduction; Particle Size; Phosphatidylcholines; Surface Properties | 2016 |
Method for measuring the unbinding energy of strongly-bound membrane-associated proteins.
Topics: Animals; Cells, Cultured; Dengue Virus; Drosophila melanogaster; Hydrogen-Ion Concentration; Kinetics; Lipid Bilayers; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Thermodynamics; Unilamellar Liposomes; Viral Envelope Proteins | 2016 |
Multiscale simulations on conformational dynamics and membrane interactions of the non-structural 2 (NS2) transmembrane domain.
Topics: Binding Sites; Lipid Bilayers; Membrane Proteins; Models, Chemical; Molecular Docking Simulation; Phosphatidylcholines; Protein Binding; Protein Conformation; Protein Domains; Structure-Activity Relationship; Viral Nonstructural Proteins | 2016 |
Theoretical study of the interactions between the first transmembrane segment of NS2 protein and a POPC lipid bilayer.
Topics: Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Membrane Proteins; Models, Biological; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Conformation; Protein Conformation, alpha-Helical; Thermodynamics; Viral Nonstructural Proteins | 2016 |
The Integrin Receptor in Biologically Relevant Bilayers: Insights from Molecular Dynamics Simulations.
Topics: Amino Acid Motifs; Binding Sites; Cholesterol; Humans; Integrin alphaVbeta3; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Structure, Tertiary; Protein Subunits; Sequence Homology, Amino Acid; Talin; Thermodynamics | 2017 |
Lipoplex-Mediated Deintercalation of Doxorubicin from Calf Thymus DNA-Doxorubicin Complex.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Calcium; Cations, Divalent; Dimyristoylphosphatidylcholine; DNA; DNA Adducts; Doxorubicin; Drug Liberation; Hydrophobic and Hydrophilic Interactions; Kinetics; Liposomes; Microscopy, Confocal; Phase Transition; Phosphatidylcholines; Static Electricity | 2016 |
Identification of a secretory phospholipase A2 from Papaver somniferum L. that transforms membrane phospholipids.
Topics: alpha-Linolenic Acid; Amino Acid Sequence; Escherichia coli; Hydrogen-Ion Concentration; Linoleic Acid; Molecular Structure; Molecular Weight; Papaver; Phosphatidylcholines; Phospholipases A2, Secretory; Phospholipids; Sequence Analysis, Protein | 2016 |
Diphenylhexatriene membrane probes DPH and TMA-DPH: A comparative molecular dynamics simulation study.
Topics: Cholesterol; Diphenylhexatriene; Fluorescence; Fluorescence Polarization; Fluorescent Dyes; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Membrane Fluidity; Molecular Dynamics Simulation; Phosphatidylcholines; Static Electricity; Thermodynamics; Water | 2016 |
Antimicrobial Peptide Simulations and the Influence of Force Field on the Free Energy for Pore Formation in Lipid Bilayers.
Topics: Amino Acid Sequence; Anti-Infective Agents; Antimicrobial Cationic Peptides; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Dynamics Simulation; Permeability; Phosphatidylcholines; Thermodynamics; Water | 2016 |
Characterizing the Size and Composition of Saposin A Lipoprotein Picodiscs.
Topics: Acetates; Animals; Chickens; Gases; Horses; Humans; Hydrogen-Ion Concentration; Lipoproteins; Molecular Dynamics Simulation; Molecular Weight; Particle Size; Phosphatidylcholines; Saposins; Spectrometry, Mass, Electrospray Ionization | 2016 |
Tuning the size of styrene-maleic acid copolymer-lipid nanoparticles (SMALPs) using RAFT polymerization for biophysical studies.
Topics: Biomimetic Materials; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Maleates; Molecular Weight; Nanoparticles; Particle Size; Phosphatidylcholines; Phosphatidylglycerols; Polymerization; Polystyrenes | 2016 |
The ganglioside GM1 interacts with the serotonin
Topics: Binding Sites; Cholesterol; G(M1) Ganglioside; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Binding; Protein Interaction Domains and Motifs; Receptor, Serotonin, 5-HT1A | 2016 |
Urea-Aromatic Stacking and Concerted Urea Transport: Conserved Mechanisms in Urea Transporters Revealed by Molecular Dynamics.
Topics: Binding Sites; Biological Transport; Hydrogen Bonding; Membrane Transport Proteins; Molecular Dynamics Simulation; Phenylalanine; Phosphatidylcholines; Protein Structure, Tertiary; Thermodynamics; Urea; Urea Transporters | 2016 |
Protonation-Driven Membrane Insertion of a pH-Low Insertion Peptide.
Topics: Amino Acid Sequence; Hydrogen-Ion Concentration; Lipid Bilayers; Membrane Proteins; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Protons; Spectrometry, Fluorescence | 2016 |
The interaction of sorafenib and regorafenib with membranes is modulated by their lipid composition.
Topics: Antineoplastic Agents; Ascorbic Acid; Cell Membrane; Cell Membrane Permeability; Cholesterol; Dithionite; Kinetics; Niacinamide; Oxidation-Reduction; Phenylurea Compounds; Phosphatidylcholines; Phosphatidylethanolamines; Pyridines; Sorafenib; Spin Labels; Staining and Labeling; Unilamellar Liposomes | 2016 |
Transition-Tempered Metadynamics Is a Promising Tool for Studying the Permeation of Drug-like Molecules through Membranes.
Topics: Algorithms; Ethanol; Lipid Bilayers; Molecular Dynamics Simulation; Pharmaceutical Preparations; Phosphatidylcholines; Thermodynamics; Trimethoprim | 2016 |
Molecular Dynamics Simulations of Amyloid β-Peptide (1-42): Tetramer Formation and Membrane Interactions.
Topics: Amyloid beta-Peptides; Animals; Cholesterol; Hydrophobic and Hydrophilic Interactions; Membrane Microdomains; Membranes, Artificial; Molecular Dynamics Simulation; Peptide Fragments; Phosphatidylcholines; Protein Aggregation, Pathological; Protein Multimerization; Protein Structure, Secondary | 2016 |
Simulations of Membrane-Disrupting Peptides II: AMP Piscidin 1 Favors Surface Defects over Pores.
Topics: Animals; Antimicrobial Cationic Peptides; Fish Proteins; Fishes; Lipid Bilayers; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation, alpha-Helical; Protein Stability; Surface Properties; Water | 2016 |
Molecular simulation study on concentration effects of rofecoxib with POPC bilayer.
Topics: Lactones; Lipid Bilayers; Molecular Dynamics Simulation; Permeability; Phosphatidylcholines; Sulfones; Thermodynamics | 2016 |
Toward elucidating the heat activation mechanism of the TRPV1 channel gating by molecular dynamics simulation.
Topics: Cryoelectron Microscopy; Gene Expression; Hot Temperature; Humans; Hydrogen Bonding; Ion Channel Gating; Lipid Bilayers; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Mutation; Phosphatidylcholines; Protein Domains; Protein Structure, Secondary; Protein Subunits; Recombinant Proteins; Structure-Activity Relationship; Thermodynamics; TRPV Cation Channels | 2016 |
Molecular dynamics of the honey bee toxin tertiapin binding to Kir3.2.
Topics: Animals; Bee Venoms; Bees; Binding Sites; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Humans; Mice; Models, Biological; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Binding; Rats; Sequence Alignment; Substrate Specificity | 2016 |
Coarse-grained simulations of hemolytic peptide δ-lysin interacting with a POPC bilayer.
Topics: Bacterial Proteins; Hemolysin Proteins; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Thermodynamics | 2016 |
Real-Time Quartz Crystal Microbalance Monitoring of Free Docosahexaenoic Acid Interactions with Supported Lipid Bilayers.
Topics: Calcium; Docosahexaenoic Acids; Lipid Bilayers; Phosphatidylcholines; Quartz Crystal Microbalance Techniques | 2016 |
Nanoscale dynamics of phospholipids reveals an optimal assembly mechanism of pore-forming proteins in bilayer membranes.
Topics: Cell Membrane; Cholesterol; Diffusion; Lipid Bilayers; Membrane Fluidity; Membrane Lipids; Molecular Conformation; Phosphatidylcholines; Phospholipids; Porins; Protein Binding | 2016 |
α-Synuclein Oligomers Stabilize Pre-Existing Defects in Supported Bilayers and Propagate Membrane Damage in a Fractal-Like Pattern.
Topics: alpha-Synuclein; Cell Membrane; Fractals; Lipid Bilayers; Microscopy, Atomic Force; Microscopy, Confocal; Phosphatidylcholines; Phosphatidylserines; Time-Lapse Imaging; Unilamellar Liposomes | 2016 |
Effect of polyelectrolyte size on multilayer conformation and dynamics at different temperatures and salt concentrations.
Topics: Anions; Diffusion; Hyaluronic Acid; Lipid Bilayers; Lipids; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines; Polyelectrolytes; Polylysine; Sodium Chloride; Temperature; Water | 2016 |
Membrane Fluidity Modulates Thermal Stability and Ligand Binding of Cytochrome P4503A4 in Lipid Nanodiscs.
Topics: Calorimetry, Differential Scanning; Circular Dichroism; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dimyristoylphosphatidylcholine; Enzyme Stability; Humans; Ketoconazole; Lipid Bilayers; Lipids; Membrane Fluidity; Models, Molecular; Nanostructures; Phosphatidylcholines; Protein Binding; Protein Denaturation; Protein Domains; Temperature; Testosterone; Thermodynamics | 2016 |
Microsecond simulation of human aquaporin 2 reveals structural determinants of water permeability and selectivity.
Topics: Aquaporin 2; Biological Transport; Diffusion; Humans; Kinetics; Molecular Dynamics Simulation; Permeability; Phosphatidylcholines; Protein Structure, Secondary; Water | 2017 |
GM1 Softens POPC Membranes and Induces the Formation of Micron-Sized Domains.
Topics: G(M1) Ganglioside; Membrane Microdomains; Phosphatidylcholines; Temperature; Unilamellar Liposomes | 2016 |
Lipid Vesicle Interaction with Hydrophobic Surfaces: A Coarse-Grained Molecular Dynamics Study.
Topics: Choline; Computer Simulation; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Lipids; Molecular Dynamics Simulation; Phosphatidylcholines; Temperature; Water; Wettability | 2016 |
Calcium-independent binding of human C-reactive protein to lysophosphatidylcholine in supported planar phospholipid monolayers.
Topics: Binding Sites; C-Reactive Protein; Calcium; Glycerophosphates; Humans; Hydrogen-Ion Concentration; Ions; Ligands; Lysophosphatidylcholines; Molecular Docking Simulation; Phosphatidylcholines; Protein Binding; Surface Plasmon Resonance; Time Factors | 2017 |
Structural and Functional Effect of an Oscillating Electric Field on the Dopamine-D3 Receptor: A Molecular Dynamics Simulation Study.
Topics: Crystallography, X-Ray; Dopamine; Electricity; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Binding; Protein Conformation; Receptors, Dopamine D3 | 2016 |
Membrane Assembly and Ion Transport Ability of a Fluorinated Nanopore.
Topics: Amino Acids; Cations, Monovalent; Halogenation; Hydrophobic and Hydrophilic Interactions; Ion Channels; Ion Transport; Lipid Bilayers; Molecular Dynamics Simulation; Nanopores; Peptides; Phosphatidylcholines; Protein Folding; Protein Multimerization; Protein Structure, Secondary; Sodium | 2016 |
Environmental Scanning Electron Microscope Imaging of Vesicle Systems.
Topics: Antigens; Cations; DNA; Imaging, Three-Dimensional; Lipid Bilayers; Liposomes; Microscopy, Electron, Scanning; Pharmaceutical Preparations; Phosphatidylcholines; Phosphatidylethanolamines | 2017 |
Assessing gastric toxicity of xanthone derivatives of anti-inflammatory activity using simulation and experimental approaches.
Topics: Anti-Inflammatory Agents; Cholesterol; Computer Simulation; Gastric Mucosa; Humans; Inflammation; Lipid Bilayers; Models, Biological; Phosphatidylcholines; Xanthones | 2017 |
Pathological levels of glucosylceramide change the biophysical properties of artificial and cell membranes.
Topics: Biophysical Phenomena; Cell Membrane; Cholesterol; Glucosylceramides; Phosphatidylcholines; Sphingomyelins | 2016 |
New Insights into Molecular Organization of Human Neuraminidase-1: Transmembrane Topology and Dimerization Ability.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Membrane; Cell-Free System; Chlorocebus aethiops; COS Cells; Escherichia coli; Gene Expression; Humans; Models, Molecular; Neuraminidase; Phosphatidylcholines; Plasmids; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Recombinant Proteins; Sialic Acids; Structural Homology, Protein; Substrate Specificity; Ubiquitin | 2016 |
Alamethicin Supramolecular Organization in Lipid Membranes from
Topics: Alamethicin; Amino Acid Sequence; Anti-Bacterial Agents; Cell Membrane; Electrophysiological Phenomena; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Protein Multimerization | 2016 |
Lipid-modified G4-decoy oligonucleotide anchored to nanoparticles: delivery and bioactivity in pancreatic cancer cells.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell-Penetrating Peptides; Humans; Lipids; Liposomes; Nanoparticles; Oligonucleotides; Pancreatic Neoplasms; Phosphatidylcholines; Promoter Regions, Genetic; Proto-Oncogene Proteins p21(ras) | 2016 |
Imidazolium Salts Mimicking the Structure of Natural Lipids Exploit Remarkable Properties Forming Lamellar Phases and Giant Vesicles.
Topics: 2-Naphthylamine; Diphenylhexatriene; Fluorescent Dyes; Imidazoles; Ionic Liquids; Laurates; Lipid Bilayers; Models, Chemical; Molecular Structure; Phosphatidylcholines; Phosphatidylserines; Transition Temperature; Unilamellar Liposomes; Viscoelastic Substances | 2017 |
Molecular Understanding of Aβ-hIAPP Cross-Seeding Assemblies on Lipid Membranes.
Topics: Amyloid beta-Peptides; Cell Membrane; Humans; Islet Amyloid Polypeptide; Membrane Lipids; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Structure, Secondary | 2017 |
What Is the Preferred Conformation of Phosphatidylserine-Copper(II) Complexes? A Combined Theoretical and Experimental Investigation.
Topics: Cations, Divalent; Copper; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Lipid Bilayers; Oxidation-Reduction; Phosphatidylcholines; Phosphatidylserines; Quantum Theory; Stereoisomerism; Thermodynamics | 2016 |
Structure and lipid-binding properties of the kindlin-3 pleckstrin homology domain.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Cytoskeletal Proteins; Escherichia coli; Gene Expression; Kinetics; Mice; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylinositols; Phosphatidylserines; Pleckstrin Homology Domains; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid | 2017 |
Weak Selectivity Predicted for Modeled Bundles of Viral Channel-Forming Protein E5 of Human Papillomavirus-16.
Topics: Amino Acid Sequence; Binding Sites; Human papillomavirus 16; Kinetics; Lipid Bilayers; Molecular Docking Simulation; Molecular Dynamics Simulation; Oncogene Proteins, Viral; Phosphatidylcholines; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Protein Multimerization; Thermodynamics; Water | 2016 |
Delineating residues for haemolytic activities of snake venom cardiotoxin 1 from Naja naja as probed by molecular dynamics simulations and in vitro validations.
Topics: Amino Acid Sequence; Animals; Antidotes; Cholesterol; Cobra Cardiotoxin Proteins; Diphosphonates; Disulfides; Elapid Venoms; Elapidae; Erythrocyte Membrane; Etidronic Acid; Hemolysis; High-Throughput Screening Assays; Humans; Imidazoles; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Protein Domains; Protein Structure, Secondary; Small Molecule Libraries; Structure-Activity Relationship; User-Computer Interface; Zoledronic Acid | 2017 |
Neutron Reflectometry reveals the interaction between functionalized SPIONs and the surface of lipid bilayers.
Topics: Biocompatible Materials; Cations; Cell Membrane; Cholesterol; Contrast Media; Dextrans; Light; Lipid Bilayers; Magnetic Resonance Imaging; Magnetite Nanoparticles; Microscopy, Electron, Transmission; Microscopy, Interference; Models, Statistical; Nanoparticles; Nanotechnology; Neutrons; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Quartz Crystal Microbalance Techniques; Scattering, Radiation; Surface Properties; Surface-Active Agents | 2017 |
Cellular Membrane Composition Requirement by Antimicrobial and Anticancer Peptide GA-K4.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Antineoplastic Agents; Benzothiazoles; Carbocyanines; Cell Membrane; Cell Membrane Permeability; Fluorescent Dyes; Kinetics; Lipid Bilayers; Lysophosphatidylcholines; Micelles; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Protein Structure, Secondary; Spectrometry, Fluorescence; Staphylococcus aureus; Unilamellar Liposomes | 2017 |
Antimicrobial activity and interactions of cationic peptides derived from Galleria mellonella cecropin D-like peptide with model membranes.
Topics: Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides; Bacteria; Cell Membrane; Fluoresceins; Hemolysis; Humans; Liposomes; Membrane Fluidity; Membranes, Artificial; Microbial Sensitivity Tests; Moths; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids | 2017 |
Interaction Forces between Lipid Rafts.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Lipid Bilayers; Membrane Microdomains; Phosphatidylcholines; Sphingomyelins | 2017 |
Toward Hydrodynamics with Solvent Free Lipid Models: STRD Martini.
Topics: Hydrodynamics; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Rotation; Stochastic Processes; Viscosity | 2016 |
Liposomes Containing Lipid-Soluble Zn(II)-Bis-dipicolylamine Derivatives Show Potential To Be Targeted to Phosphatidylserine on the Surface of Cancer Cells.
Topics: Amines; Anions; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Drug Carriers; Humans; Lipid Bilayers; Liposomes; MCF-7 Cells; Membrane Fusion; Nanoparticles; Neoplasms; Phosphatidylcholines; Phosphatidylserines; Picolinic Acids; Unilamellar Liposomes; Zinc | 2017 |
Insertion of Neurotransmitters into a Lipid Bilayer Membrane and Its Implication on Membrane Stability: A Molecular Dynamics Study.
Topics: Lipid Bilayers; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Neurotransmitter Agents; Phosphatidylcholines; Phosphatidylethanolamines | 2017 |
Islet Amyloid Polypeptide Membrane Interactions: Effects of Membrane Composition.
Topics: Amino Acid Sequence; Amyloid; Cell Membrane; Cell Membrane Permeability; Cholesterol; Glycerylphosphorylcholine; Humans; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Kinetics; Lipid Bilayers; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Sodium Chloride; Sphingomyelins | 2017 |
Communication: Alamethicin can capture lipid-like molecules in the membrane.
Topics: Alamethicin; Amino Acid Sequence; Cell Membrane; Electron Spin Resonance Spectroscopy; Phosphatidylcholines; Temperature | 2017 |
A High-Throughput Fluorometric Assay for Lipid-Protein Binding.
Topics: Carrier Proteins; Cell Membrane; Cloning, Molecular; Escherichia coli; Fluorescent Dyes; Gene Expression; Glutathione Transferase; Green Fluorescent Proteins; High-Throughput Screening Assays; Membrane Lipids; p-Dimethylaminoazobenzene; Phosphatidylcholines; Phosphatidylinositol Phosphates; Protein Binding; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Spectrometry, Fluorescence; Unilamellar Liposomes | 2017 |
Fluorescence-Based In Situ Quantitative Imaging for Cellular Lipids.
Topics: 2-Naphthylamine; Adaptor Proteins, Vesicular Transport; Biosensing Techniques; Carrier Proteins; Cell Membrane; Cloning, Molecular; Cysteine; Escherichia coli; Fluorescent Dyes; Gene Expression; Glutathione Transferase; Membrane Lipids; Molecular Imaging; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Recombinant Fusion Proteins; Signal Transduction; Unilamellar Liposomes | 2017 |
Measuring Diacylglycerol Kinase-θ Activity and Binding.
Topics: Adenosine Triphosphate; Animals; Diacylglycerol Kinase; Diglycerides; Enzyme Assays; Intracellular Membranes; Isoenzymes; Kinetics; Mammals; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phosphorylation; Protein Binding; Saccharomyces cerevisiae; Surface Properties; Unilamellar Liposomes | 2017 |
Effect of the Southeast Asian Ovalocytosis Deletion on the Conformational Dynamics of Signal-Anchor Transmembrane Segment 1 of Red Cell Anion Exchanger 1 (AE1, Band 3, or SLC4A1).
Topics: Amino Acid Sequence; Anion Exchange Protein 1, Erythrocyte; Base Sequence; Elliptocytosis, Hereditary; Erythrocytes; Gene Expression; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Molecular Dynamics Simulation; Phosphatidylcholines; Proline; Protein Domains; Protein Folding; Protein Structure, Secondary; Sequence Deletion | 2017 |
Targeting Type 2 Diabetes with C-Glucosyl Dihydrochalcones as Selective Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitors: Synthesis and Biological Evaluation.
Topics: Chalcones; Diabetes Mellitus, Type 2; Glucosides; HEK293 Cells; Humans; Membranes, Artificial; Molecular Docking Simulation; Phosphatidylcholines; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2017 |
Computational Models of the Gastrointestinal Environment. 1. The Effect of Digestion on the Phase Behavior of Intestinal Fluids.
Topics: Bile; Bile Acids and Salts; Body Fluids; Chemistry, Pharmaceutical; Computer Simulation; Digestion; Gastrointestinal Tract; Glycodeoxycholic Acid; Magnetic Resonance Spectroscopy; Micelles; Molecular Dynamics Simulation; Oleic Acid; Phosphatidylcholines; Phospholipids; Water | 2017 |
Depth-Dependent Membrane Ordering by Hemagglutinin Fusion Peptide Promotes Fusion.
Topics: Anthracenes; Fluorescence Polarization; Fluorescent Dyes; Hemagglutinin Glycoproteins, Influenza Virus; Lipid Bilayers; Membrane Fusion; Mutation; Orthomyxoviridae; Peptides; Phosphatidylcholines; Protein Conformation; Stearates; Viral Fusion Proteins | 2017 |
Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid-β.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Humans; Lipid Bilayers; Phosphatidylcholines; Protein Aggregates; Protein Structure, Secondary | 2017 |
Detection of lipid-induced structural changes of the Marburg virus matrix protein VP40 using hydrogen/deuterium exchange-mass spectrometry.
Topics: Deuterium Exchange Measurement; Marburgvirus; Mass Spectrometry; Models, Chemical; Phosphatidylcholines; Phosphatidylserines; Protein Multimerization; Protein Structure, Quaternary; Viral Matrix Proteins | 2017 |
Partitioning of caffeine in lipid bilayers reduces membrane fluidity and increases membrane thickness.
Topics: Caffeine; Lipid Bilayers; Membrane Fluidity; Molecular Dynamics Simulation; Phosphatidylcholines; X-Ray Diffraction | 2017 |
Modeling Lung Surfactant Interactions with Benzo[a]pyrene.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Benzo(a)pyrene; Molecular Dynamics Simulation; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; Surface Tension | 2017 |
Effects of Membrane PEGylation on Entry and Location of Antifungal Drug Itraconazole and Their Pharmacological Implications.
Topics: Antifungal Agents; Chemistry, Pharmaceutical; Drug Delivery Systems; Fluorescence; Itraconazole; Lipid Bilayers; Liposomes; Membranes; Phosphatidylcholines; Polyethylene Glycols; Polymers; Protective Agents; Solubility; Surface Properties | 2017 |
Electrostatic anchoring precedes stable membrane attachment of SNAP25/SNAP23 to the plasma membrane.
Topics: Amino Acid Motifs; Animals; Binding Sites; Cell Membrane; Cloning, Molecular; Escherichia coli; Gene Expression; Liposomes; Lipoylation; PC12 Cells; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Plasmids; Protein Binding; Protein Processing, Post-Translational; Protein Transport; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Static Electricity; Synaptosomal-Associated Protein 25; Vesicular Transport Proteins | 2017 |
Measurement of Hanatoxin-Induced Membrane Thinning with Lamellar X-ray Diffraction.
Topics: Peptides; Phosphatidylcholines; Phosphatidylglycerols; Spider Venoms; X-Ray Diffraction | 2017 |
The Long-Chain Sphingoid Base of Ceramides Determines Their Propensity for Lateral Segregation.
Topics: Ceramides; Phosphatidylcholines | 2017 |
Computer simulations of the diffusion of Na
Topics: Chlorides; Diffusion; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Sodium | 2017 |
Development of a liquid chromatography-mass spectrometry based enzyme activity assay for phosphatidylcholine-specific phospholipase C.
Topics: Animals; Brain; Chromatography, Liquid; Diglycerides; Enzyme Activation; Enzyme Assays; Hydrolysis; Kinetics; Mass Spectrometry; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Signal Transduction; Synaptosomes; Type C Phospholipases | 2017 |
Non-linear van't Hoff behavior in pulmonary surfactant model membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Hydrogen-Ion Concentration; Membranes, Artificial; Models, Chemical; Osmolar Concentration; Phase Transition; Phosphatidylcholines; Phosphatidylglycerols; Pulmonary Surfactants; Surface Properties; Temperature; Thermodynamics | 2017 |
Single-Molecule Peptide-Lipid Affinity Assay Reveals Interplay between Solution Structure and Partitioning.
Topics: Adenosine Triphosphatases; Bacterial Proteins; Kinetics; Lipid Bilayers; Molecular Dynamics Simulation; Peptide Fragments; Phosphatidylcholines; Solutions; Thermodynamics; Water | 2017 |
Detachment of Membrane Bound Virions by Competitive Ligand Binding Induced Receptor Depletion.
Topics: Animals; Cattle; Cholera Toxin; G(M1) Ganglioside; Kinetics; Ligands; Lipid Bilayers; Phosphatidylcholines; Simian virus 40; Virion; Virus Attachment | 2017 |
Sulpiride, Amisulpride, Thioridazine, and Olanzapine: Interaction with Model Membranes. Thermodynamic and Structural Aspects.
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Calorimetry; Dynamic Light Scattering; Electron Spin Resonance Spectroscopy; Membranes, Artificial; Models, Chemical; Molecular Structure; Olanzapine; Phosphatidylcholines; Phosphatidylglycerols; Protons; Sulpiride; Thermodynamics; Thioridazine; Water | 2017 |
Expression, Functional Characterization, and Solid-State NMR Investigation of the G Protein-Coupled GHS Receptor in Bilayer Membranes.
Topics: Dimyristoylphosphatidylcholine; Ghrelin; Humans; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Receptors, Ghrelin; Recombinant Proteins | 2017 |
Interdigitation between Triglycerides and Lipids Modulates Surface Properties of Lipid Droplets.
Topics: Lipid Droplets; Lipids; Molecular Conformation; Molecular Dynamics Simulation; Particle Size; Phosphatidylcholines; Phospholipids; Pressure; Surface Tension; Triglycerides; Triolein | 2017 |
Identification of a conserved 8 aa insert in the PIP5K protein in the Saccharomycetaceae family of fungi and the molecular dynamics simulations and structural analysis to investigate its potential functional role.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Amino Acid Sequence; Catalytic Domain; Conserved Sequence; Humans; Kinetics; Lipid Bilayers; Molecular Dynamics Simulation; Mutagenesis, Insertional; Phosphatidylcholines; Phosphatidylinositol Phosphates; Phosphotransferases (Alcohol Group Acceptor); Phylogeny; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Static Electricity; Structural Homology, Protein; Substrate Specificity; Thermodynamics | 2017 |
Normal vibrational modes of phospholipid bilayers observed by low-frequency Raman scattering.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Elastic Modulus; Lipid Bilayers; Phosphatidylcholines; Spectrum Analysis, Raman; Suspensions; Temperature; Vibration; Water | 2017 |
Pulsatile Lipid Vesicles under Osmotic Stress.
Topics: Dermoscopy; Diffusion; Hypotonic Solutions; Lipid Bilayers; Models, Biological; Osmotic Pressure; Phosphatidylcholines; Stress, Physiological; Sucrose; Thermodynamics; Unilamellar Liposomes | 2017 |
Two cations, two mechanisms: interactions of sodium and calcium with zwitterionic lipid membranes.
Topics: Calcium; Cholesterol; Computer Simulation; Membranes, Artificial; Models, Chemical; Optical Imaging; Phosphatidylcholines; Sodium | 2017 |
Membrane localization and dynamics of geranylgeranylated Rab5 hypervariable region.
Topics: Amino Acid Sequence; Binding Sites; Cholesterol; Diterpenes; Endosomes; Glycosylation; Humans; Lipid Bilayers; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositol Phosphates; Phosphatidylserines; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; rab5 GTP-Binding Proteins; Signal Transduction; Sphingomyelins; Thermodynamics | 2017 |
Complexin Binding to Membranes and Acceptor t-SNAREs Explains Its Clamping Effect on Fusion.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Escherichia coli; Lipid Bilayers; Liposomes; Mutation; Nerve Tissue Proteins; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Rats; Recombinant Proteins; Surface Properties; Synaptosomal-Associated Protein 25; Syntaxin 1; Vesicle-Associated Membrane Protein 2 | 2017 |
Comparative molecular dynamics study of neuromyelitis optica-immunoglobulin G binding to aquaporin-4 extracellular domains.
Topics: Amino Acid Motifs; Aquaporin 4; Autoantibodies; Binding Sites; Epitopes; Humans; Hydrogen Bonding; Immunoglobulin G; Lipid Bilayers; Models, Molecular; Molecular Dynamics Simulation; Mutation; Neuromyelitis Optica; Phosphatidylcholines; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Protein Multimerization; Thermodynamics | 2017 |
Position-Dependent Diffusion Tensors in Anisotropic Media from Simulation: Oxygen Transport in and through Membranes.
Topics: Alkanes; Bayes Theorem; Biological Transport; Cell Membrane; Cell Membrane Permeability; Diffusion; Lipid Bilayers; Molecular Conformation; Molecular Dynamics Simulation; Oxygen; Phosphatidylcholines; Thermodynamics; Water | 2017 |
Theoretical insights into the mechanism of ferroptosis suppression via inactivation of a lipid peroxide radical by liproxstatin-1.
Topics: Free Radicals; Iron; Kinetics; Lipid Peroxides; Molecular Dynamics Simulation; Phosphatidylcholines; Quantum Theory; Quinoxalines; Spiro Compounds; Structure-Activity Relationship; Thermodynamics; Ubiquinone | 2017 |
H
Topics: Apolipoprotein A-I; Biocatalysis; Cysteine; Electron Transport; Enzymes, Immobilized; Glutathione; Humans; Hydrogen Sulfide; Kinetics; Models, Molecular; Nanoparticles; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; Peptide Fragments; Phosphatidylcholines; Recombinant Proteins; Solubility; Ubiquinone | 2017 |
New Continuum Approaches for Determining Protein-Induced Membrane Deformations.
Topics: Cell Membrane; Computer Simulation; Elasticity; Gramicidin; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Membrane Proteins; Models, Biological; Molecular Dynamics Simulation; Phosphatidylcholines; Surface Tension; TRPV Cation Channels | 2017 |
Digitonin does not flip across cholesterol-poor membranes.
Topics: Cholesterol; Digitonin; Lipid Bilayers; Liposomes; Micelles; Phosphatidylcholines; Phosphatidylserines; Thermodynamics | 2017 |
Electrical resonance of Amphotericin B channel activity in lipidic membranes.
Topics: Amphotericin B; Electricity; Lipid Bilayers; Phosphatidylcholines; Time Factors | 2017 |
Membrane Interactions of hIAPP Monomer and Oligomer with Lipid Membranes by Molecular Dynamics Simulations.
Topics: Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Islet Amyloid Polypeptide; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Protein Aggregates; Protein Conformation; Static Electricity; Water | 2017 |
Influence of Cholesterol on the Oxygen Permeability of Membranes: Insight from Atomistic Simulations.
Topics: Biological Transport; Cell Membrane Permeability; Cholesterol; Diffusion; Hydrophobic and Hydrophilic Interactions; Kinetics; Lipid Bilayers; Molecular Dynamics Simulation; Oxygen; Phosphatidylcholines; Solubility; Water | 2017 |
Molecular Dynamics Simulation Reveals Unique Interplays Between a Tarantula Toxin and Lipid Membranes.
Topics: Lipid Bilayers; Membrane Lipids; Membrane Potentials; Molecular Dynamics Simulation; Phosphatidylcholines; Spider Venoms | 2017 |
Molecular dynamics simulation of the membrane binding and disruption mechanisms by antimicrobial scorpion venom-derived peptides.
Topics: Amino Acid Sequence; Antimicrobial Cationic Peptides; Binding Sites; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Scorpion Venoms | 2018 |
Model membrane size-dependent amyloidogenesis of Alzheimer's amyloid-β peptides.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Calorimetry; Circular Dichroism; Humans; Kinetics; Microscopy, Atomic Force; Peptide Fragments; Phosphatidylcholines; Unilamellar Liposomes | 2017 |
Transport of nanoparticles across pulmonary surfactant monolayer: a molecular dynamics study.
Topics: Drug Carriers; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Nanoparticles; Phosphatidylcholines; Phospholipid Ethers; Pulmonary Surfactants | 2017 |
Phosphorylation of a full length amyloid-β peptide modulates its amyloid aggregation, cell binding and neurotoxic properties.
Topics: Amyloid; Amyloid beta-Peptides; Animals; Cell Membrane; Cerebral Cortex; Cholesterol; Embryo, Mammalian; Humans; Mice; Mice, Inbred C57BL; Neurons; Peptide Fragments; Phosphatidylcholines; Phosphatidylserines; Phosphorylation; Primary Cell Culture; Protein Aggregates; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Secondary; Proteolysis; Unilamellar Liposomes | 2017 |
Enhanced Antibacterial Activity of Ent-Labdane Derivatives of Salvic Acid (7α-Hydroxy-8(17)-ent-Labden-15-Oic Acid): Effect of Lipophilicity and the Hydrogen Bonding Role in Bacterial Membrane Interaction.
Topics: Anti-Bacterial Agents; Carbon-13 Magnetic Resonance Spectroscopy; Cell Membrane; Diterpenes; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydrogen Bonding; Lipid Bilayers; Lipids; Microbial Sensitivity Tests; Phosphatidylcholines; Proton Magnetic Resonance Spectroscopy; Structure-Activity Relationship | 2017 |
Serum amyloid A self-assembles with phospholipids to form stable protein-rich nanoparticles with a distinct structure: A hypothetical function of SAA as a "molecular mop" in immune response.
Topics: Animals; Cholesterol; Chromatography, Gel; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Lipoproteins, HDL; Mice; Microscopy, Electron; Nanoparticles; Particle Size; Phosphatidylcholines; Phospholipids; Protein Stability; Serum Amyloid A Protein; Spectrometry, Fluorescence | 2017 |
DNA cytoskeleton for stabilizing artificial cells.
Topics: Artificial Cells; Cytoskeleton; DNA; Drug Delivery Systems; Fatty Acids, Monounsaturated; Fluorescent Dyes; HeLa Cells; Humans; Lipids; Liposomes; Nanostructures; Nanotechnology; Nucleic Acid Conformation; Osmotic Pressure; Phosphatidylcholines; Quaternary Ammonium Compounds; Rhodamines; Stress, Mechanical; Time Factors | 2017 |
Ultra-low friction between boundary layers of hyaluronan-phosphatidylcholine complexes.
Topics: Cryoelectron Microscopy; Dimyristoylphosphatidylcholine; Friction; Hyaluronic Acid; Lubricants; Phosphatidylcholines | 2017 |
Delivering Transmembrane Peptide Complexes to the Gas Phase Using Nanodiscs and Electrospray Ionization.
Topics: Acetates; Butanols; Cell Membrane; Dimyristoylphosphatidylcholine; Gases; Gramicidin; Lipid Bilayers; Molecular Dynamics Simulation; Nanostructures; Peptides; Phosphatidylcholines; Protein Multimerization; Spectrometry, Mass, Electrospray Ionization | 2017 |
The Functional Amyloid Orb2A Binds to Lipid Membranes.
Topics: Amino Acid Sequence; Amyloid; Animals; Binding Sites; Circular Dichroism; Drosophila melanogaster; Drosophila Proteins; Electron Spin Resonance Spectroscopy; Escherichia coli; Microscopy, Electron, Transmission; mRNA Cleavage and Polyadenylation Factors; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Protein Isoforms; Protein Structure, Secondary; Surface Properties; Transcription Factors; Unilamellar Liposomes | 2017 |
The Energetics of Chromophore Binding in the Visual Photoreceptor Rhodopsin.
Topics: Animals; Calorimetry; Cattle; Cholic Acids; Dynamic Light Scattering; Fluorescence Resonance Energy Transfer; Hydrodynamics; Kinetics; Lipid Bilayers; Micelles; Phosphatidylcholines; Photobleaching; Protein Binding; Protein Stability; Receptors, Adrenergic, beta; Retinaldehyde; Rhodopsin; Thermodynamics; Water | 2017 |
Accelerated molecular dynamics simulation analysis of MSI-594 in a lipid bilayer.
Topics: Amino Acid Sequence; Antimicrobial Cationic Peptides; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Dynamics Simulation; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Phosphatidylserines; Protein Structure, Secondary | 2017 |
Interactions between β2-Adrenoceptor Ligands and Membrane: Atomic-Level Insights from Magic-Angle Spinning NMR.
Topics: Adrenergic beta-2 Receptor Agonists; Formoterol Fumarate; Hydrophobic and Hydrophilic Interactions; Indans; Ligands; Liposomes; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Quinolones; Salmeterol Xinafoate | 2017 |
Molecular dynamics simulations of T-2410 and T-2429 HIV fusion inhibitors interacting with model membranes: Insight into peptide behavior, structure and dynamics.
Topics: Amino Acid Sequence; Cholesterol; HIV; HIV Fusion Inhibitors; Humans; Hydrogen Bonding; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Sequence Data; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Sequence Alignment; Thermodynamics | 2017 |
Vesicle aggregates as a model for primitive cellular assemblies.
Topics: Cryoelectron Microscopy; Dynamic Light Scattering; Ferritins; Nucleic Acids; Phosphatidylcholines; Polyglutamic Acid; RNA, Transfer; Unilamellar Liposomes | 2017 |
Drude Polarizable Force Field for Molecular Dynamics Simulations of Saturated and Unsaturated Zwitterionic Lipids.
Topics: Diffusion; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Quantum Theory; Thermodynamics | 2017 |
Non-Covalent Assembly Method that Simultaneously Endows a Liposome Surface with Targeting Ligands, Protective PEG Chains, and Deep-Red Fluorescence Reporter Groups.
Topics: Agglutination; Cholesterol; Cyclobutanes; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Jurkat Cells; Ligands; Liposomes; Microscopy, Fluorescence; Organometallic Compounds; Phenols; Phosphatidylcholines; Picolines; Polyethylene Glycols; Polymers; Staphylococcus aureus | 2017 |
Membrane Curvature and Lipid Composition Synergize To Regulate N-Ras Anchor Recruitment.
Topics: Genes, ras; Liposomes; Models, Molecular; Phosphatidylcholines; Pressure; Protein Binding; Surface Properties | 2017 |
Structural modeling for the open state of an NMDA receptor.
Topics: Cell Membrane; Glycine; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Conformation; Protein Domains; Receptors, N-Methyl-D-Aspartate | 2017 |
Membrane-bound human orphan cytochrome P450 2U1: Sequence singularities, construction of a full 3D model, and substrate docking.
Topics: Arachidonic Acid; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Humans; Membranes, Artificial; Molecular Docking Simulation; Phosphatidylcholines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Structural Homology, Protein; Structure-Activity Relationship | 2017 |
Ions Modulate Stress-Induced Nanotexture in Supported Fluid Lipid Bilayers.
Topics: Anti-Infective Agents; Calcium Chloride; Glycerylphosphorylcholine; Ions; Lipid Bilayers; Microscopy, Atomic Force; Nanostructures; Phosphatidylcholines; Potassium Chloride; Sodium Chloride; Stress, Mechanical; Surface Properties; Temperature; Tromethamine | 2017 |
Molecular Dynamics Methodologies for Probing Cannabinoid Ligand/Receptor Interaction.
Topics: Animals; Cannabinoid Receptor Modulators; Cannabinoids; Humans; Ligands; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Binding; Receptors, Cannabinoid; Signal Transduction | 2017 |
Structures of apolipoprotein A-I in high density lipoprotein generated by electron microscopy and biased simulations.
Topics: Apolipoprotein A-I; Cholesterol; Humans; Lipoproteins, HDL; Microscopy, Electron; Phosphatidylcholines; Phospholipids; Protein Conformation; Protein Structure, Secondary | 2017 |
Properties of POPC/POPE supported lipid bilayers modified with hydrophobic quantum dots on polyelectrolyte cushions.
Topics: Cryoelectron Microscopy; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Phosphatidylcholines; Phosphatidylethanolamines; Phosphorylcholine; Polyelectrolytes; Quantum Dots | 2017 |
A-type ECG and EGCG dimers inhibit 3T3-L1 differentiation by binding to cholesterol in lipid rafts.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Catechin; Cell Differentiation; Cholesterol; Dimerization; Lipid Bilayers; Membrane Microdomains; Mice; Microscopy, Fluorescence; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines | 2017 |
Intrinsically Disordered Stress Protein COR15A Resides at the Membrane Surface during Dehydration.
Topics: Arabidopsis Proteins; Cell Membrane; Phosphatidylcholines; Protein Conformation, alpha-Helical; Protein Folding; Surface Properties; Water | 2017 |
Multiplexed silicon photonic sensor arrays enable facile characterization of coagulation protein binding to nanodiscs with variable lipid content.
Topics: Factor VIIa; Factor X; High-Throughput Screening Assays; Humans; Kinetics; Lipid Bilayers; Nanostructures; Optical Phenomena; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylserines; Protein Array Analysis; Protein C; Prothrombin; Recombinant Proteins; Silicon | 2017 |
Microfluidic Capture and Multiplex Immunofluorescence of Circulating Tumor Cells to Identify Cancer of Origin.
Topics: Antibodies, Monoclonal; Antibody Specificity; Antigens, Neoplasm; Avidin; Epithelial Cell Adhesion Molecule; Fluorescent Antibody Technique; HCT116 Cells; Humans; Immunoconjugates; Lab-On-A-Chip Devices; Lipid Bilayers; Neoplasms; Neoplastic Cells, Circulating; Phosphatidylcholines; Polymethyl Methacrylate; Protein Binding | 2017 |
Comparison of Physicochemical Membrane Properties of Vesicles Modified with Guanidinium Derivatives.
Topics: Chemistry, Physical; Guanidine; Hydrogen-Ion Concentration; Lipid Bilayers; Liposomes; Phosphatidylcholines; Spectroscopy, Fourier Transform Infrared | 2017 |
Interaction of lysozyme with a tear film lipid layer model: A molecular dynamics simulation study.
Topics: Adsorption; Cholesterol Esters; Humans; Kinetics; Molecular Dynamics Simulation; Muramidase; Phosphatidylcholines; Phosphatidylethanolamines; Sphingomyelins; Sulfoglycosphingolipids; Surface Tension; Tears; Thermodynamics; Triolein; Water | 2017 |
Oxysterols Versus Cholesterol in Model Neuronal Membrane. I. The Case of 7-Ketocholesterol. The Langmuir Monolayer Study.
Topics: Cell Membrane; Ketocholesterols; Lipid Bilayers; Models, Chemical; Neurons; Phosphatidylcholines; Sphingomyelins | 2017 |
Biophysical and biological properties of small linear peptides derived from crotamine, a cationic antimicrobial/antitumoral toxin with cell penetrating and cargo delivery abilities.
Topics: Amino Acid Sequence; Animals; Antifungal Agents; Candida; Cell-Penetrating Peptides; Crotalid Venoms; Crotalus; Cysteine; DNA; Drug Carriers; Kinetics; Microbial Sensitivity Tests; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Static Electricity; Structure-Activity Relationship; Trichosporon; Unilamellar Liposomes | 2017 |
Cholesterol affects the interaction between an ionic liquid and phospholipid vesicles. A study by differential scanning calorimetry and nanoplasmonic sensing.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Aliivibrio fischeri; Calorimetry, Differential Scanning; Cholesterol; Ionic Liquids; Lipid Bilayers; Organophosphorus Compounds; Phosphatidylcholines | 2017 |
Membrane perturbing activities and structural properties of the frog-skin derived peptide Esculentin-1a(1-21)NH
Topics: Amino Acid Sequence; Amphibian Proteins; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Biofilms; Cholesterol; Cytotoxins; Kinetics; Leucine; Lipid Bilayers; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Plankton; Protein Conformation, alpha-Helical; Pseudomonas aeruginosa; Ranidae; Serine; Skin; Spheroplasts; Stereoisomerism; Structure-Activity Relationship | 2017 |
Effects of High Pressure on Phospholipid Bilayers.
Topics: Diffusion; Elasticity; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Pressure; Thermodynamics; Water | 2017 |
Sterol-recognition ability and membrane-disrupting activity of Ornithogalum saponin OSW-1 and usual 3-O-glycosyl saponins.
Topics: Antineoplastic Agents, Phytogenic; beta-Cyclodextrins; Biological Transport; Cholestenones; Cholesterol; Digitonin; Dimyristoylphosphatidylcholine; Erythrocyte Membrane; Fluoresceins; Glycyrrhizic Acid; Hemolysis; Humans; Membrane Lipids; Oleanolic Acid; Ornithogalum; Phosphatidylcholines; Saponins; Unilamellar Liposomes | 2017 |
Pore formation in lipid membrane II: Energy landscape under external stress.
Topics: Biomechanical Phenomena; Cell Membrane Permeability; Dimyristoylphosphatidylcholine; Elasticity; Kinetics; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Porosity; Thermodynamics | 2017 |
Liposomes entrapping β-cyclodextrin/ibuprofen inclusion complex: Role of the host and the guest on the bilayer integrity and microviscosity.
Topics: beta-Cyclodextrins; Ibuprofen; Lipid Bilayers; Liposomes; Phosphatidylcholines; Viscosity | 2017 |
Raman spectroscopy reveals the lipid phase transition in preimplantation mouse embryos during freezing.
Topics: Animals; Blastocyst; Cryopreservation; Female; Freezing; Lipid Bilayers; Lipids; Mice; Molecular Conformation; Phase Transition; Phosphatidylcholines; Spectrum Analysis, Raman | 2017 |
Nanodisc-based kinetic assays reveal distinct effects of phospholipid headgroups on the phosphoenzyme transition of sarcoplasmic reticulum Ca
Topics: Animals; Calcium-Transporting ATPases; Kinetics; Lipid Bilayers; Molecular Structure; Phosphatidylcholines; Phospholipids; Protein Conformation; Rabbits; Sarcoplasmic Reticulum; Static Electricity | 2017 |
Influence of the membrane environment on cholesterol transfer.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Biological Transport; Cholesterol; Kinetics; Phosphatidylcholines; Sphingomyelins; Thermodynamics; Unilamellar Liposomes | 2017 |
Differential Interaction of Antimicrobial Peptides with Lipid Structures Studied by Coarse-Grained Molecular Dynamics Simulations.
Topics: Amphibian Proteins; Antimicrobial Cationic Peptides; Computer Simulation; Lipid Bilayers; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines | 2017 |
Effect of Lipid Surface Composition on the Formation and Structure of Fibrin Clots.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Adsorption; Animals; Cattle; Fibrin; Fibrinogen; Kinetics; Liposomes; Nephelometry and Turbidimetry; Phosphatidylcholines; Phosphatidylglycerols; Solutions; Thrombin | 2017 |
Is the cholesterol bilayer domain a barrier to oxygen transport into the eye lens?
Topics: Biological Transport; Cataract; Cell Membrane; Cholesterol; Diffusion; Electron Spin Resonance Spectroscopy; Humans; Kinetics; Lens, Crystalline; Lipid Bilayers; Molecular Dynamics Simulation; Oxygen; Phosphatidylcholines; Spin Labels | 2018 |
Direct visualization of the lateral structure of giant vesicles composed of pseudo-binary mixtures of sulfatide, asialo-GM1 and GM1 with POPC.
Topics: 2-Naphthylamine; Carbocyanines; Fluorescent Dyes; G(M1) Ganglioside; Laurates; Lipid Bilayers; Microscopy, Fluorescence; Molecular Structure; Phosphatidylcholines; Sulfoglycosphingolipids; Unilamellar Liposomes | 2018 |
Substitution impact of highly conserved arginine residue at position 75 in GJB1 gene in association with X-linked Charcot-Marie-tooth disease: A computational study.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Binding Sites; Charcot-Marie-Tooth Disease; Computational Biology; Connexins; Gap Junction beta-1 Protein; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Mutation, Missense; Phosphatidylcholines; Protein Binding; Protein Conformation; Sequence Homology, Amino Acid | 2018 |
New free-exchange model of EmrE transport.
Topics: Antiporters; Binding Sites; Biological Transport; Dicyclohexylcarbodiimide; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression; Hydrogen-Ion Concentration; Kinetics; Molecular Dynamics Simulation; Onium Compounds; Organophosphorus Compounds; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Proteolipids; Protons; Recombinant Proteins; Substrate Specificity; Thermodynamics; Xenobiotics | 2017 |
FRET Analysis of the Promiscuous yet Specific Interactions of the HIV-1 Vpu Transmembrane Domain.
Topics: Bone Marrow Stromal Antigen 2; Cell Membrane; Fluorescence Resonance Energy Transfer; HIV-1; Human Immunodeficiency Virus Proteins; Phosphatidylcholines; Protein Binding; Protein Domains; Protein Multimerization; Protein Structure, Quaternary; Protein Structure, Secondary; Signaling Lymphocytic Activation Molecule Family; Substrate Specificity; Viral Regulatory and Accessory Proteins | 2017 |
Cholesterol Promotes Protein Binding by Affecting Membrane Electrostatics and Solvation Properties.
Topics: Animals; Cell Membrane; Cholesterol; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Conformation; Protein Domains; Retroviridae Proteins; Rous sarcoma virus; Solvents; Static Electricity | 2017 |
Structure and electrical properties of DNA nanotubes embedded in lipid bilayer membranes.
Topics: Algorithms; Cell Membrane; DNA; Electromagnetic Phenomena; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Membrane Fluidity; Molecular Dynamics Simulation; Nanopores; Nanotubes; Nucleic Acid Conformation; Phosphatidylcholines | 2018 |
Understanding the inhibitory mechanism of BIT225 drug against p7 viroporin using computational study.
Topics: Antiviral Agents; Guanidines; Hepacivirus; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Molecular Dynamics Simulation; Osmolar Concentration; Phosphatidylcholines; Pyrazoles; Viral Proteins | 2018 |
Specific binding of human C-reactive protein towards supported monolayers of binary and engineered phospholipids.
Topics: Adsorption; C-Reactive Protein; Calcium; Humans; Hydrogen-Ion Concentration; Lysophosphatidylcholines; Membrane Lipids; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines; Phospholipids; Protein Binding; Surface Plasmon Resonance; Surface Properties; Unilamellar Liposomes | 2018 |
Antioxidant activity of hydroxytyrosyl esters studied in liposome models.
Topics: 2-Naphthylamine; Antioxidants; Esters; Fluoresceins; Laurates; Liposomes; Phenylethyl Alcohol; Phosphatidylcholines; Spectrometry, Fluorescence; Unilamellar Liposomes | 2018 |
Probing molecular forces in multi-component physiological membranes.
Topics: Algorithms; Cluster Analysis; Endoplasmic Reticulum; Golgi Apparatus; Lipid Bilayers; Mitochondria; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines | 2018 |
Integrated microfluidic biosensing platform for simultaneous confocal microscopy and electrophysiological measurements on bilayer lipid membranes and ion channels.
Topics: Biosensing Techniques; Fluorescent Dyes; Gramicidin; Ion Channels; Lab-On-A-Chip Devices; Lipid Bilayers; Microfluidic Analytical Techniques; Microscopy, Confocal; Phosphatidylcholines; Phosphatidylethanolamines | 2018 |
The orientation and stability of the GPCR-Arrestin complex in a lipid bilayer.
Topics: Arrestin; Hydrogen Bonding; Lipid Bilayers; Molecular Dynamics Simulation; Multiprotein Complexes; Mutation; Phosphatidylcholines; Protein Conformation; Protein Stability; Rhodopsin | 2017 |
The effect of hydronium ions on the structure of phospholipid membranes.
Topics: Hydrogen Bonding; Lipid Bilayers; Molecular Dynamics Simulation; Onium Compounds; Phosphatidylcholines; Phospholipids; Water | 2017 |
Flow Cytometric Analysis To Evaluate Morphological Changes in Giant Liposomes As Observed in Electrofusion Experiments.
Topics: Cholesterol; Cobalt; Edetic Acid; Electrochemical Techniques; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Liposomes; Phosphatidylcholines; Phosphatidylglycerols | 2018 |
Do protocells preferentially retain macromolecular solutes upon division/fragmentation? A study based on the extrusion of POPC giant vesicles.
Topics: Albumins; Artificial Cells; Arylsulfonates; Carbonic Anhydrases; Dextrans; Exosomes; Fluorescein-5-isothiocyanate; Fluoresceins; Hydrogen-Ion Concentration; Kinetics; Lipids; Macromolecular Substances; Microscopy, Confocal; Models, Theoretical; Molecular Weight; Phosphatidylcholines; Phospholipids; Stochastic Processes; Synthetic Biology; Systems Biology | 2018 |
Preparation and Membrane Properties of Oxidized Ceramide Derivatives.
Topics: Cell Membrane; Ceramides; Lipid Bilayers; Oxidation-Reduction; Phase Transition; Phosphatidylcholines; Sphingomyelins; Unilamellar Liposomes | 2018 |
Intracellular Transfer of Na
Topics: Amino Acid Motifs; Binding Sites; Carbachol; Cations, Monovalent; Humans; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Ion Transport; Kinetics; Ligands; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Receptor, Muscarinic M2; Sodium; Static Electricity; Thermodynamics | 2018 |
Structural design of intrinsically fluorescent oxysterols.
Topics: Hydroxycholesterols; Liposomes; Microscopy, Fluorescence; Molecular Dynamics Simulation; Oxysterols; Phosphatidylcholines; Spectrophotometry, Ultraviolet | 2018 |
Investigation of the interaction of amyloid β peptide (11-42) oligomers with a 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) membrane using molecular dynamics simulation.
Topics: Amyloid beta-Peptides; Cholesterol; Humans; Hydrophobic and Hydrophilic Interactions; Membrane Lipids; Membranes, Artificial; Molecular Dynamics Simulation; Oligopeptides; Peptide Fragments; Phosphatidylcholines; Thermodynamics | 2018 |
Design and synthesis of cell selective α/β-diastereomeric peptidomimetic with potent in vivo antibacterial activity against methicillin resistant S. Aureus.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Enterococcus faecalis; Erythrocytes; Escherichia coli; Female; Hemolysis; Humans; Keratinocytes; Lipid Bilayers; Methicillin-Resistant Staphylococcus aureus; Mice, Inbred BALB C; Microbial Sensitivity Tests; Peptidomimetics; Phosphatidylcholines; Phosphatidylglycerols; Pseudomonas aeruginosa; Stereoisomerism | 2018 |
Intrinsic Curvature-Mediated Transbilayer Coupling in Asymmetric Lipid Vesicles.
Topics: Lipid Bilayers; Mechanical Phenomena; Phosphatidylcholines; Phosphatidylethanolamines | 2018 |
Microwave measurement of giant unilamellar vesicles in aqueous solution.
Topics: Cholesterol; Microfluidics; Microwaves; Permeability; Phosphatidylcholines; Sphingomyelins; Unilamellar Liposomes; Water | 2018 |
Critical effects of polar fluorescent probes on the interaction of DHA with POPC supported lipid bilayers.
Topics: 4-Chloro-7-nitrobenzofurazan; Docosahexaenoic Acids; Fluorescent Dyes; Lipid Bilayers; Molecular Conformation; Phosphatidylcholines; Quartz Crystal Microbalance Techniques; Rhodamines | 2018 |
Alamethicin self-assembling in lipid membranes: concentration dependence from pulsed EPR of spin labels.
Topics: Alamethicin; Amino Acid Sequence; Dimerization; Electron Spin Resonance Spectroscopy; Kinetics; Lipid Bilayers; Phosphatidylcholines; Spin Labels; Water | 2018 |
Effects of carotenoids on lipid bilayers.
Topics: beta Carotene; Carotenoids; Cholesterol; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Zeaxanthins | 2018 |
Eicosapentaenoic acid and docosahexaenoic acid have distinct membrane locations and lipid interactions as determined by X-ray diffraction.
Topics: Cholesterol; Docosahexaenoic Acids; Eicosapentaenoic Acid; Isomerism; Membrane Fluidity; Phosphatidylcholines; Scattering, Small Angle; Temperature; Unilamellar Liposomes; X-Ray Diffraction | 2018 |
Effects of electroformation protocol parameters on quality of homogeneous GUV populations.
Topics: Electricity; Electrodes; Flow Cytometry; Microscopy, Fluorescence; Phosphatidylcholines; Unilamellar Liposomes | 2018 |
Fatty Acid/Phospholipid Blended Membranes: A Potential Intermediate State in Protocellular Evolution.
Topics: Fatty Acids; Membranes, Artificial; Oleic Acid; Phosphatidylcholines; Phospholipids | 2018 |
De Novo Synthesis of Basal Bacterial Cell Division Proteins FtsZ, FtsA, and ZipA Inside Giant Vesicles.
Topics: Bacterial Proteins; Carrier Proteins; Cell Cycle Proteins; Cell Membrane; Cell-Free System; Cytoskeletal Proteins; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Green Fluorescent Proteins; Guanosine Triphosphate; Hydrolysis; Imaging, Three-Dimensional; Phosphatidylcholines; Phosphatidylglycerols; Protein Engineering; Unilamellar Liposomes | 2018 |
Cholesterol Protects the Oxidized Lipid Bilayer from Water Injury: An All-Atom Molecular Dynamics Study.
Topics: Cholesterol; Lipid Bilayers; Molecular Dynamics Simulation; Oxidation-Reduction; Oxidative Stress; Phosphatidylcholines; Phospholipids; Phosphorylcholine | 2018 |
Antimicrobial action of the cationic peptide, chrysophsin-3: a coarse-grained molecular dynamics study.
Topics: Amino Acid Sequence; Antimicrobial Cationic Peptides; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Conformation; Surface Properties | 2018 |
Accurate Binding of Sodium and Calcium to a POPC Bilayer by Effective Inclusion of Electronic Polarization.
Topics: Binding Sites; Calcium; Electricity; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Sodium | 2018 |
Membrane Deformation Induces Clustering of Norovirus Bound to Glycosphingolipids in a Supported Cell-Membrane Mimic.
Topics: Carbocyanines; Fluorescence; Fluorescent Dyes; Glycosphingolipids; Gold; Humans; Lipid Bilayers; Metal Nanoparticles; Microscopy, Fluorescence; Norovirus; Phosphatidylcholines | 2018 |
Molecular dynamics simulations showing 1-palmitoyl-2-oleoyl-phosphatidylcholine (POPC) membrane mechanoporation damage under different strain paths.
Topics: Algorithms; Biomechanical Phenomena; Lipid Bilayers; Models, Theoretical; Molecular Dynamics Simulation; Phosphatidylcholines; Phospholipids | 2019 |
Molecular Dynamics Simulations of Human Antimicrobial Peptide LL-37 in Model POPC and POPG Lipid Bilayers.
Topics: Antimicrobial Cationic Peptides; Cathelicidins; Humans; Lipid Bilayers; Models, Biological; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylglycerols; Protein Structure, Secondary | 2018 |
Time-Resolved Neutron Interferometry and the Mechanism of Electromechanical Coupling in Voltage-Gated Ion Channels.
Topics: Anesthetics; Deuterium Exchange Measurement; Escherichia coli; Gene Expression; Humans; Interferometry; Lipid Bilayers; Molecular Dynamics Simulation; Neutrons; Phosphatidylcholines; Potassium Channels, Voltage-Gated; Protein Binding; Protein Domains; Recombinant Proteins; X-Rays | 2018 |
Effects of Urea and TMAO on Lipid Self-Assembly under Osmotic Stress Conditions.
Topics: Calorimetry; Dimyristoylphosphatidylcholine; Magnetic Resonance Spectroscopy; Methylamines; Molecular Dynamics Simulation; Osmotic Pressure; Phosphatidylcholines; Urea; Water | 2018 |
Modulation of Catalytic Promiscuity during Hydrogen Sulfide Oxidation.
Topics: Biocatalysis; Glutathione; Humans; Hydrogen Sulfide; Kinetics; Nanostructures; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; Phosphatidylcholines; Substrate Specificity; Sulfhydryl Compounds; Sulfites | 2018 |
Bexarotene Binds to the Amyloid Precursor Protein Transmembrane Domain, Alters Its α-Helical Conformation, and Inhibits γ-Secretase Nonselectively in Liposomes.
Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Bexarotene; Cholesterol; HEK293 Cells; Humans; Liposomes; Molecular Structure; Neuroprotective Agents; Phosphatidylcholines; Protein Conformation, alpha-Helical; Protein Domains; Receptor, Notch1; Static Electricity | 2018 |
Docosahexaenoic acid regulates the formation of lipid rafts: A unified view from experiment and simulation.
Topics: Calorimetry, Differential Scanning; Cholesterol; Docosahexaenoic Acids; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Microdomains; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Sphingomyelins | 2018 |
Sculpting and fusing biomimetic vesicle networks using optical tweezers.
Topics: Amino Acids; Bacterial Toxins; Biological Transport; Biomimetic Materials; Carbocyanines; Gene Expression; Green Fluorescent Proteins; Hemolysin Proteins; Lasers; Lipid Bilayers; Membrane Fusion; Optical Tweezers; Phosphatidylcholines; Phosphatidylethanolamines; Ribonucleotides; RNA, Transfer; Sodium Chloride | 2018 |
Molecular Structure and Permeability at the Interface between Phase-Separated Membrane Domains.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Gels; Lipid Bilayers; Molecular Dynamics Simulation; Permeability; Phase Transition; Phosphatidylcholines; Thermodynamics; Transition Temperature | 2018 |
Link between Membrane Composition and Permeability to Drugs.
Topics: Anthracenes; Cholesterol; Dideoxyadenosine; Hydrocortisone; Kinetics; Lipid Bilayers; Molecular Dynamics Simulation; Permeability; Phosphatidylcholines; Thermodynamics | 2018 |
Influence of Dimethyl Sulfoxide on the Low-Temperature Behavior of Cholesterol-Loaded Palmitoyl-oleyl-phosphatidylcholine Membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Dimethyl Sulfoxide; Hydrogen Bonding; Liposomes; Phosphatidylcholines; Spectroscopy, Fourier Transform Infrared; Temperature; Water | 2018 |
Fluorescence quenching by lipid encased nanoparticles shows that amyloid-β has a preferred orientation in the membrane.
Topics: Amyloid beta-Peptides; Cholesterol; Fluoresceins; Fluorescence; Fluorescent Dyes; Lipid Bilayers; Metal Nanoparticles; Peptide Fragments; Phosphatidylcholines; Phosphatidylglycerols; Silver; Spectrometry, Fluorescence; Spectrum Analysis, Raman | 2018 |
Statistical Analysis of Bending Rigidity Coefficient Determined Using Fluorescence-Based Flicker-Noise Spectroscopy.
Topics: Fluorescence; Glycerylphosphorylcholine; Lipid Bilayers; Phosphatidylcholines; Spectrometry, Fluorescence; Unilamellar Liposomes | 2018 |
Quantitative Assessment of Methods Used To Obtain Rate Constants from Molecular Dynamics Simulations-Translocation of Cholesterol across Lipid Bilayers.
Topics: Cholesterol; Diffusion; Kinetics; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Thermodynamics | 2018 |
The fabrication and in vitro properties of antibacterial polydopamine-LL-37-POPC coatings on micro-arc oxidized titanium.
Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Cathelicidins; Coated Materials, Biocompatible; Escherichia coli; Indoles; Microbial Sensitivity Tests; Oxidation-Reduction; Particle Size; Phosphatidylcholines; Polymers; Staphylococcus aureus; Surface Properties; Titanium | 2018 |
Reorganization of Ternary Lipid Mixtures of Nonphosphorylated Phosphatidylinositol Interacting with Angiomotin.
Topics: Escherichia coli; Intercellular Signaling Peptides and Proteins; Liposomes; Membrane Proteins; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Protein Domains; Scattering, Small Angle; Temperature; X-Ray Diffraction | 2018 |
Designing effective anticancer-radiopeptides. A Molecular Dynamics study of their interaction with model tumor and healthy cell membranes.
Topics: Amino Acid Sequence; Antimicrobial Cationic Peptides; Bromine; Cathelicidins; Humans; Hydrogen-Ion Concentration; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Thermodynamics | 2018 |
Lipid binding attenuates channel closure of the outer membrane protein OmpF.
Topics: Bacterial Outer Membrane Proteins; Cation Transport Proteins; Escherichia coli Proteins; Hydrogen-Ion Concentration; Models, Chemical; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylglycerols; Porins; Protein Binding; Protein Conformation; Spectrometry, Mass, Electrospray Ionization; Voltage-Dependent Anion Channels; Voltage-Gated Sodium Channels | 2018 |
Pore-Forming Monopeptides as Exceptionally Active Anion Channels.
Topics: Anions; Hydrogen Bonding; Ion Transport; Membranes, Artificial; Models, Molecular; Peptides; Phosphatidylcholines; Porosity; Protein Conformation, alpha-Helical; Protein Multimerization | 2018 |
Supported Lipid Bilayers for Atomic Force Microscopy Studies.
Topics: alpha-Synuclein; Aluminum Silicates; Lipid Bilayers; Microscopy, Atomic Force; Phosphatidylcholines; Reproducibility of Results; Time-Lapse Imaging | 2018 |
Indium-111 labeling of high-density lipoprotein-mimicking phospholipid-styrene maleic acid copolymer complexes and its biodistribution in mice.
Topics: Animals; Biomimetic Materials; Indium Radioisotopes; Isotope Labeling; Lipoproteins, HDL; Male; Maleates; Mice; Nanoparticles; Phosphatidylcholines; Polystyrenes; Tissue Distribution | 2018 |
A coarse-grained approach to studying the interactions of the antimicrobial peptides aurein 1.2 and maculatin 1.1 with POPG/POPE lipid mixtures.
Topics: Amino Acid Sequence; Amphibian Proteins; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Anura; Binding Sites; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs | 2018 |
Amyloid-β Peptide Triggers Membrane Remodeling in Supported Lipid Bilayers Depending on Their Hydrophobic Thickness.
Topics: Amyloid beta-Peptides; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Membrane Fluidity; Microscopy, Fluorescence; Peptide Fragments; Phosphatidylcholines; Quartz Crystal Microbalance Techniques | 2018 |
Revealing cardiolipins influence in the construction of a significant mitochondrial membrane model.
Topics: Animals; Cardiolipins; Cattle; Dynamic Light Scattering; Fluorescence Polarization; Lipid Bilayers; Magnetic Resonance Spectroscopy; Mitochondrial Membranes; Models, Molecular; Phosphatidylcholines; Phosphatidylethanolamines; Transition Temperature | 2018 |
Antimicrobial cell penetrating peptides with bacterial cell specificity: pharmacophore modelling, quantitative structure activity relationship and molecular dynamics simulation.
Topics: Antimicrobial Cationic Peptides; Cell-Penetrating Peptides; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylglycerols; Quantitative Structure-Activity Relationship; Staphylococcus aureus | 2019 |
The effects of oxidised phospholipids and cholesterol on the biophysical properties of POPC bilayers.
Topics: Cell Membrane; Cholesterol; Lipid Bilayers; Lipids; Molecular Conformation; Molecular Dynamics Simulation; Oxygen; Phosphatidylcholines; Phospholipids; Signal Transduction | 2019 |
Cholesterol and phosphatidylethanolamine lipids exert opposite effects on membrane modulations caused by the M2 amphipathic helix.
Topics: Cell Membrane; Cholesterol; Electron Spin Resonance Spectroscopy; Hydrogen Bonding; Lipid Bilayers; Lipids; Membrane Lipids; Micelles; Microscopy, Atomic Force; Nanotechnology; Peptides; Phosphatidylcholines; Phosphatidylethanolamines | 2019 |
Reactive Oxygen and Nitrogen Species at Phospholipid Bilayers: Peroxynitrous Acid and Its Homolysis Products.
Topics: Hydroxyl Radical; Lipid Bilayers; Molecular Conformation; Molecular Dynamics Simulation; Nitrogen Dioxide; Peroxynitrous Acid; Phosphatidylcholines; Thermodynamics | 2018 |
Mechanism of Binding of Antifungal Antibiotic Amphotericin B to Lipid Membranes: An Insight from Combined Single-Membrane Imaging, Microspectroscopy, and Molecular Dynamics.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Amphotericin B; Antifungal Agents; Cholesterol; Molecular Dynamics Simulation; Phosphatidylcholines | 2018 |
DNA-Corralled Nanodiscs for the Structural and Functional Characterization of Membrane Proteins and Viral Entry.
Topics: Cholesterol; DNA; Humans; Lipid Bilayers; Membrane Proteins; Nanostructures; Nucleic Acid Conformation; Particle Size; Phosphatidylcholines; Phosphatidylglycerols; Photosynthetic Reaction Center Complex Proteins; Poliovirus; Receptors, Virus; Rhodobacter sphaeroides; Virus Internalization; Voltage-Dependent Anion Channel 1 | 2018 |
Entry from the Lipid Bilayer: A Possible Pathway for Inhibition of a Peptide G Protein-Coupled Receptor by a Lipophilic Small Molecule.
Topics: Animals; Binding Sites; Fibroblasts; Humans; Lactones; Ligands; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Structure; Phosphatidylcholines; Protein Binding; Protein Conformation; Pyridines; Rats; Receptor, PAR-1 | 2018 |
Conformational Transitions of Melittin between Aqueous and Lipid Phases: Comparison of Simulations with Experiments.
Topics: Animals; Bees; Cholesterol; Circular Dichroism; Melitten; Molecular Dynamics Simulation; Phase Transition; Phosphatidylcholines; Protein Structure, Secondary; Thermodynamics; Unilamellar Liposomes; Water | 2018 |
A mixed alchemical and equilibrium dynamics to simulate heterogeneous dense fluids: Illustrations for Lennard-Jones mixtures and phospholipid membranes.
Topics: Algorithms; Lipid Bilayers; Models, Chemical; Molecular Dynamics Simulation; Monte Carlo Method; Phosphatidylcholines | 2018 |
Molecular transport through membranes: Accurate permeability coefficients from multidimensional potentials of mean force and local diffusion constants.
Topics: Biological Transport; Diffusion; Lipid Bilayers; Models, Chemical; Molecular Dynamics Simulation; Permeability; Phosphatidylcholines; Thermodynamics; Trimethoprim | 2018 |
Wavelength-Selective Fluorescence of a Model Transmembrane Peptide: Constrained Dynamics of Interfacial Tryptophan Anchors.
Topics: Amino Acid Sequence; Membrane Proteins; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Spectrometry, Fluorescence; Tryptophan | 2018 |
Supported lipid bilayers with encapsulated quantum dots (QDs) via liposome fusion: effect of QD size on bilayer formation and structure.
Topics: Lipid Bilayers; Liposomes; Microscopy, Atomic Force; Particle Size; Phosphatidylcholines; Phosphatidylethanolamines; Quantum Dots; Quartz Crystal Microbalance Techniques; Synchrotrons | 2018 |
Membrane curvature allosterically regulates the phosphatidylinositol cycle, controlling its rate and acyl-chain composition of its lipid intermediates.
Topics: Animals; Cell Line; Cholesterol; Diacylglycerol Kinase; Diglycerides; Enzyme Assays; Humans; Liposomes; Membrane Fusion; Micelles; Molecular Structure; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Spodoptera; Surface Properties | 2018 |
A Quantitative Model of Daptomycin Binding to Lipid Bilayers.
Topics: Anti-Bacterial Agents; Calcium; Daptomycin; Kinetics; Lipid Bilayers; Models, Chemical; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Unilamellar Liposomes | 2018 |
The effect of pH on the lytic activity of a synthetic mastoparan-like peptide in anionic model membranes.
Topics: Anions; Hydrogen-Ion Concentration; Intercellular Signaling Peptides and Proteins; Particle Size; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Surface Properties; Wasp Venoms | 2018 |
Atomistic mechanism of the constitutive activation of PDGFRA via its transmembrane domain.
Topics: Allosteric Site; Computational Biology; Computer Simulation; Humans; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis; Phosphatidylcholines; Point Mutation; Protein Domains; Protein Multimerization; Receptor, Platelet-Derived Growth Factor alpha | 2019 |
Sphingomyelin Stereoisomers Reveal That Homophilic Interactions Cause Nanodomain Formation.
Topics: Cell Membrane; Cholesterol; Fluorescence; Gels; Membrane Microdomains; Phosphatidylcholines; Sphingomyelins; Stereoisomerism | 2018 |
Macrophage reprogramming by negatively charged membrane phospholipids controls infection.
Topics: Animals; Cells, Cultured; Cellular Reprogramming; Coinfection; Extracellular Vesicles; Female; Macrophages, Peritoneal; Male; Mice; Mice, Inbred ICR; Phosphatidylcholines; Phosphatidylserines; Sepsis | 2019 |
Molecular Dynamics of Ion Conduction through the Selectivity Filter of the Na
Topics: Bacterial Proteins; Lipid Bilayers; Membrane Potentials; Molecular Dynamics Simulation; Phosphatidylcholines; Potassium; Protein Conformation; Sodium; Voltage-Gated Sodium Channels | 2018 |
Methionine 170 is an Environmentally Sensitive Membrane Anchor in the Disordered HVR of K-Ras4B.
Topics: Amino Acid Sequence; Humans; Lipid Bilayers; Methionine; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylserines; Protein Domains; Proto-Oncogene Proteins p21(ras); Static Electricity | 2018 |
The Impact of O-Glycosylation on Cyanidin Interaction with POPC Membranes: Structure-Activity Relationship.
Topics: Anthocyanins; Glycosylation; Hydrogen Peroxide; Lipid Peroxidation; Phosphatidylcholines; Structure-Activity Relationship | 2018 |
Molecular Dynamics Simulations of Ion Selectivity in a Claudin-15 Paracellular Channel.
Topics: Animals; Chlorides; Claudins; Lipid Bilayers; Mice; Molecular Dynamics Simulation; Phosphatidylcholines; Potassium; Sodium; Water | 2018 |
Lipid composition and salt concentration as regulatory factors of the anion selectivity of VDAC studied by coarse-grained molecular dynamics simulations.
Topics: Animals; Mice; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Salts; Static Electricity; Surface Properties; Voltage-Dependent Anion Channels | 2019 |
Glucosylceramide acyl chain length is sensed by the glycolipid transfer protein.
Topics: Animals; Carrier Proteins; Cattle; Escherichia coli; Glucosylceramides; Membranes, Artificial; Molecular Structure; Phosphatidylcholines; Protein Conformation; Surface Plasmon Resonance; Tryptophan | 2018 |
Spatial Presentation of Cholesterol Units on a DNA Cube as a Determinant of Membrane Protein-Mimicking Functions.
Topics: Biomimetic Materials; Cholesterol; DNA; Membrane Proteins; Molecular Dynamics Simulation; Nanopores; Phosphatidylcholines; Unilamellar Liposomes | 2019 |
AFM Imaging Suggests Receptor-Free Penetration of Lipid Bilayers by Toxins.
Topics: Bacterial Proteins; Bacterial Toxins; Clostridioides difficile; Exotoxins; Hydrogen-Ion Concentration; Lipid Bilayers; Microscopy, Atomic Force; Phosphatidylcholines; Phosphatidylethanolamines; Photorhabdus; Protein Binding; Protein Conformation; Rhodamines | 2019 |
Amyloid β-Peptide Interaction with Membranes: Can Chaperones Change the Fate?
Topics: Amyloid beta-Peptides; Animals; Cattle; Chaperonin 60; Gangliosides; Lipid Bilayers; Peptide Fragments; Phosphatidylcholines; Phosphatidylserines; Protein Multimerization; Unilamellar Liposomes | 2019 |
Interaction of statins with phospholipid bilayers studied by solid-state NMR spectroscopy.
Topics: Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Bilayers; Lovastatin; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phospholipids; Pravastatin; Simvastatin | 2019 |
Highly Efficient Protein-free Membrane Fusion: A Giant Vesicle Study.
Topics: Fluorescence Resonance Energy Transfer; Membrane Fusion; Phosphatidylcholines; Phosphatidylglycerols; Static Electricity; Unilamellar Liposomes | 2019 |
Chemical Additives Enable Native Mass Spectrometry Measurement of Membrane Protein Oligomeric State within Intact Nanodiscs.
Topics: Aquaporins; Cation Transport Proteins; Dioxolanes; Escherichia coli; Escherichia coli Proteins; Glycerol; Imidazoles; Indicators and Reagents; Lipid Bilayers; Nanostructures; Phosphatidylcholines; Phosphatidylglycerols; Propane; Protein Multimerization; Spectrometry, Mass, Electrospray Ionization; Static Electricity | 2019 |
Contrasting roles of oxidized lipids in modulating membrane microdomains.
Topics: Lipid Bilayers; Lipid Peroxidation; Membrane Microdomains; Oxidants, Photochemical; Oxidation-Reduction; Phosphatidylcholines; Phosphorylcholine; Unilamellar Liposomes | 2019 |
Probing the Dynamics and Structural Topology of the Reconstituted Human KCNQ1 Voltage Sensor Domain (Q1-VSD) in Lipid Bilayers Using Electron Paramagnetic Resonance Spectroscopy.
Topics: Circular Dichroism; Electron Spin Resonance Spectroscopy; Humans; KCNQ1 Potassium Channel; Lipid Bilayers; Mutagenesis, Site-Directed; Phosphatidylcholines; Phosphatidylglycerols; Protein Domains; Spin Labels | 2019 |
In vitro gene expression and detergent-free reconstitution of active proteorhodopsin in lipid vesicles.
Topics: Detergents; Gene Expression; Lipids; Phosphatidylcholines; Protein Biosynthesis; Rhodopsins, Microbial; Spectrometry, Fluorescence; Transcription, Genetic; Unilamellar Liposomes | 2019 |
Mega-stokes pyrene ceramide conjugates for STED imaging of lipid droplets in live cells.
Topics: Ceramides; Cholesterol; Density Functional Theory; Fluorescence; Fluorescent Dyes; HeLa Cells; Humans; Light; Lipid Bilayers; Lipid Droplets; Microscopy, Fluorescence; Models, Chemical; Phosphatidylcholines; Pyrenes; Sphingomyelins | 2019 |
Circularized and solubility-enhanced MSPs facilitate simple and high-yield production of stable nanodiscs for studies of membrane proteins in solution.
Topics: Amino Acid Sequence; Bacterial Proteins; Chromatography, Ion Exchange; Circular Dichroism; Lipid Bilayers; Membrane Proteins; Nanostructures; Phosphatidylcholines; Protein Aggregates; Protein Denaturation; Recombinant Proteins; Scattering, Small Angle; Sequence Alignment; Sequence Homology, Amino Acid; Solubility; Solutions; Thermotoga maritima; X-Ray Diffraction | 2019 |
Nanovesicles Versus Nanoparticle-Supported Lipid Bilayers: Massive Differences in Bilayer Structures and in Diffusivities of Lipid Molecules and Nanoconfined Water.
Topics: Diffusion; Lipid Bilayers; Liposomes; Molecular Dynamics Simulation; Nanoparticles; Phosphatidylcholines; Water | 2019 |
Core-Shell Modeling of Light Scattering by Vesicles: Effect of Size, Contents, and Lamellarity.
Topics: Light; Lipid Bilayers; Models, Theoretical; Oleic Acid; Phosphatidylcholines; Scattering, Radiation | 2019 |
The apoA-I mimetic peptide 4F protects apolipoprotein A-I from oxidative damage.
Topics: Amino Acid Sequence; Apolipoprotein A-I; ATP Binding Cassette Transporter 1; Cell Line; Cholesterol; Humans; Hypochlorous Acid; Mass Spectrometry; Oxidation-Reduction; Peptides; Phosphatidylcholines | 2019 |
Solid-state NMR structural investigations of peptide-based nanodiscs and of transmembrane helices in bicellar arrangements.
Topics: Amino Acid Sequence; Dimyristoylphosphatidylcholine; Lipid Bilayers; Magnetic Resonance Spectroscopy; Nanostructures; Peptides; Phosphatidylcholines; Polymers | 2019 |
Analyses based on statistical thermodynamics for large difference between thermophilic rhodopsin and xanthorhodopsin in terms of thermostability.
Topics: Amino Acid Sequence; Bacterial Proteins; Bacteroidetes; Entropy; Hydrogen Bonding; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Conformation, alpha-Helical; Protein Folding; Protein Stability; Rhodopsins, Microbial; Statistics as Topic; Thermodynamics; Thermus thermophilus; Water | 2019 |
A Shared Mechanism for the Folding of Voltage-Gated K
Topics: Aeropyrum; Amino Acid Sequence; Archaeal Proteins; Lipid Bilayers; Mutation; Phosphatidylcholines; Potassium Channels, Voltage-Gated; Protein Domains; Protein Folding; Temperature; Unilamellar Liposomes | 2019 |
Conformational analysis of apolipoprotein E3/E4 heteromerization.
Topics: Apolipoprotein E3; Apolipoprotein E4; Circular Dichroism; Fluorescence; Fluorescence Resonance Energy Transfer; Humans; Phosphatidylcholines; Protein Conformation; Protein Denaturation; Protein Interaction Domains and Motifs; Protein Multimerization | 2019 |
Graphene quantum dot assisted translocation of drugs into a cell membrane.
Topics: Doxorubicin; Drug Carriers; Graphite; Membranes, Artificial; Phosphatidylcholines; Quantum Dots | 2019 |
Studied on the dynamic adsorption process of Lycium barbarum polysaccharide in the POPC/DPPC monolayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Adsorption; Drugs, Chinese Herbal; Microscopy, Atomic Force; Phosphatidylcholines | 2019 |
Indole Pulse Signalling Regulates the Cytoplasmic pH of E. coli in a Memory-Like Manner.
Topics: Cell Membrane; Cell Proliferation; Culture Media; Cytoplasm; Escherichia coli; Flow Cytometry; Hydrogen-Ion Concentration; Indoles; Periodicity; Phosphatidylcholines; Photons; Signal Transduction; Spectrometry, Fluorescence; Unilamellar Liposomes | 2019 |
Characterization of the self-assembly and size dependent structural properties of dietary mixed micelles by molecular dynamics simulations.
Topics: Bile Acids and Salts; Diet; Micelles; Molecular Dynamics Simulation; Phosphatidylcholines | 2019 |
Interaction of POPC, DPPC, and POPE with the μ opioid receptor: A coarse-grained molecular dynamics study.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Lipid Bilayers; Lipids; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Binding; Protein Conformation; Receptors, Opioid, mu | 2019 |
Lipid Fingerprints and Cofactor Dynamics of Light-Harvesting Complex II in Different Membranes.
Topics: Binding Sites; Biophysical Phenomena; Coenzymes; Light-Harvesting Protein Complexes; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Photosynthesis; Plants; Protein Binding; Protein Conformation; Protein Multimerization; Structure-Activity Relationship; Thylakoids | 2019 |
Synthesis and application of the blue fluorescent amino acid l-4-cyanotryptophan to assess peptide-membrane interactions.
Topics: Amino Acid Sequence; Cell Membrane; Fluorescence; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; HeLa Cells; Humans; Membrane Proteins; Microscopy, Fluorescence; Phosphatidylcholines; Protein Binding; Tryptophan; Unilamellar Liposomes | 2019 |
Effect of the Incorporation of Functionalized Cyclodextrins in the Liposomal Bilayer.
Topics: beta-Cyclodextrins; Lipid Bilayers; Phosphatidylcholines; Unilamellar Liposomes | 2019 |
Fluid surface coatings for solid-state nanopores: comparison of phospholipid bilayers and archaea-inspired lipid monolayers.
Topics: Archaea; Diffusion; Lipid Bilayers; Nanopores; Phosphatidylcholines; Phospholipids; Surface Properties; Unilamellar Liposomes | 2019 |
Bacterial Model Membranes Deform ( resp. Persist) upon Ni
Topics: Binding Sites; Lipid Bilayers; Lipopolysaccharides; Nickel; O Antigens; Phosphatidylcholines; Protein Binding; Salmonella enterica; Static Electricity | 2019 |
Bilayer Membranes with Frequent Flip-Flops Have Tensionless Leaflets.
Topics: Cell Membrane; G(M1) Ganglioside; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines | 2019 |
Sensitivity and Resilience of Phosphatidylcholine and Phosphatidylethanolamine Lipid Membranes against Cholinium Glycinate Biocompatible Ionic Liquid.
Topics: Choline; Glycine; Hydrogen Bonding; Ionic Liquids; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Water | 2019 |
Molecular crowding effects on the distribution of amphiphiles in biological media.
Topics: Animals; Cattle; Fluorescence; Hot Temperature; Kinetics; Lipid Bilayers; Macromolecular Substances; Phosphatidylcholines; Serum Albumin, Bovine; Solubility; Surface-Active Agents; Water | 2019 |
Characterization of apolipoprotein A-I peptide phospholipid interaction and its effect on HDL nanodisc assembly.
Topics: Amino Acid Sequence; Animals; Apolipoprotein A-I; Dynamic Light Scattering; Kinetics; Lipid Bilayers; Lipoproteins, HDL; Male; Nanoparticles; Peptides; Phosphatidylcholines; Phospholipids; Rats, Sprague-Dawley; Solubility; Spectroscopy, Fourier Transform Infrared; Sphingomyelins; Thermodynamics; Vibration | 2019 |
Investigations of the Structure, Topology, and Interactions of the Transmembrane Domain of the Lipid-Sorting Protein p24 Being Highly Selective for Sphingomyelin-C18.
Topics: Amino Acid Sequence; Humans; Lipid Bilayers; Liposomes; Membrane Proteins; Micelles; Peptide Fragments; Phosphatidylcholines; Protein Binding; Protein Conformation, alpha-Helical; Protein Domains; Sphingomyelins | 2019 |
Identification of the Initial Steps in Signal Transduction in the α4β2 Nicotinic Receptor: Insights from Equilibrium and Nonequilibrium Simulations.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Humans; Hydrogen-Ion Concentration; Ligands; Lipid Bilayers; Molecular Dynamics Simulation; Nicotine; Phosphatidylcholines; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Subunits; Receptors, Nicotinic; Signal Transduction; Thermodynamics | 2019 |
Enhanced Ion Yields Using High Energy Water Cluster Beams for Secondary Ion Mass Spectrometry Analysis and Imaging.
Topics: Angiotensins; Animals; Brain; Cardiolipins; HeLa Cells; Humans; Ions; Phosphatidylcholines; Rats; Spectrometry, Mass, Secondary Ion; Trehalose; Water | 2019 |
Structure and Function in Antimicrobial Piscidins: Histidine Position, Directionality of Membrane Insertion, and pH-Dependent Permeabilization.
Topics: Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides; Fish Proteins; Fishes; Fluoresceins; Fluorescent Dyes; Histidine; Hydrogen-Ion Concentration; Lipid Bilayers; Molecular Dynamics Simulation; Permeability; Phosphatidylcholines; Phosphatidylglycerols; Surface-Active Agents | 2019 |
Solid-State NMR Investigations of the MHC II Transmembrane Domains: Topological Equilibria and Lipid Interactions.
Topics: Amino Acid Motifs; HLA-DQ alpha-Chains; HLA-DQ beta-Chains; Humans; Lipid Bilayers; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Protein Domains | 2019 |
Insight into the cellular effects of nitrated phospholipids: Evidence for pleiotropic mechanisms of action.
Topics: Cell Adhesion; Cell Line, Tumor; Cytoskeleton; Endocrine Cells; Fatty Acids; Gene Expression Regulation; Genes, Reporter; Green Fluorescent Proteins; Humans; Lipid Peroxidation; Luminescent Proteins; Mutation; Neuroglia; Nitrates; Nitric Oxide; Nitric Oxide Donors; Phosphatidylcholines; PPAR gamma; Red Fluorescent Protein; Vimentin | 2019 |
A Guide to Tracking Single Membrane Proteins and Their Interactions in Supported Lipid Bilayers.
Topics: Biomimetics; Detergents; Diffusion; Endoplasmic Reticulum; Evaluation Studies as Topic; Lipid Bilayers; Membrane Proteins; NADPH-Ferrihemoprotein Reductase; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; Receptors, Serotonin; Single Molecule Imaging | 2019 |
Assembly of α-synuclein aggregates on phospholipid bilayers.
Topics: alpha-Synuclein; Computer Simulation; Humans; Lipid Bilayers; Models, Chemical; Phosphatidylcholines; Phosphatidylserines; Protein Aggregates | 2019 |
Antifouling Lipid Membranes over Protein A for Orientation-Controlled Immunosensing in Undiluted Serum and Plasma.
Topics: Animals; Antibodies, Immobilized; Cholera Toxin; Gold; Humans; Immunoassay; Immunoglobulin Fab Fragments; Immunoglobulin G; Membranes, Artificial; Mice; Phosphatidylcholines; Phosphatidylglycerols; Proof of Concept Study; Staphylococcal Protein A | 2019 |
Accelerating Membrane Simulations with Hydrogen Mass Repartitioning.
Topics: Cell Membrane; Diffusion; Glycophorins; Humans; Hydrogen; Lipid Bilayers; Membrane Proteins; Molecular Dynamics Simulation; Motion; Peptides; Phosphatidylcholines; Protein Multimerization; Receptors, G-Protein-Coupled; Thermodynamics | 2019 |
Enhance the efficiency of 5-fluorouracil targeted delivery by using a prodrug approach as a novel strategy for prolonged circulation time and improved permeation.
Topics: Antineoplastic Agents; Delayed-Action Preparations; Fluorouracil; Lipid Bilayers; Maleimides; Molecular Dynamics Simulation; Nanotubes, Carbon; Permeability; Phosphatidylcholines; Prodrugs | 2019 |
Magnesium interactions with a CX26 connexon in lipid bilayers.
Topics: Amino Acids; Calcium; Connexin 26; Electrons; Lipid Bilayers; Magnesium; Molecular Dynamics Simulation; Phosphatidylcholines | 2019 |
Ionizable amino lipid interactions with POPC: implications for lipid nanoparticle function.
Topics: Cations; Deuterium; Gene Transfer Techniques; Hydrogen-Ion Concentration; Molecular Dynamics Simulation; Nanoparticles; Phosphatidylcholines; RNA, Small Interfering | 2019 |
Permeation of beta-defensin-3 encapsulated with polyethylene glycol in lung surfactant models at air-water interface.
Topics: beta-Defensins; Cholesterol; Drug Compounding; Humans; Lysophosphatidylcholines; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Phosphatidylserines; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactants; Static Electricity; Thermodynamics; Water | 2019 |
A selective membrane-targeting repurposed antibiotic with activity against persistent methicillin-resistant
Topics: Animals; Anti-Bacterial Agents; Bithionol; Cell Membrane; Cell Membrane Permeability; Cholesterol; Disease Models, Animal; Drug Repositioning; Drug Synergism; Gentamicins; Lipid Bilayers; Membrane Fluidity; Methicillin-Resistant Staphylococcus aureus; Molecular Dynamics Simulation; Phosphatidylcholines; Structure-Activity Relationship; Unilamellar Liposomes | 2019 |
Ions Modulate Key Interactions between pHLIP and Lipid Membranes.
Topics: Ions; Membrane Lipids; Membrane Proteins; Osmolar Concentration; Phosphatidylcholines; Protein Structure, Secondary; Sodium Chloride | 2019 |
Unsaturated lipid bilayers at cryogenic temperature: librational dynamics of chain-labeled lipids from pulsed and CW-EPR.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Electron Spin Resonance Spectroscopy; Kinetics; Lipid Bilayers; Molecular Conformation; Motion; Phase Transition; Phosphatidylcholines; Spin Labels; Temperature; Thermodynamics | 2019 |
The Effects of Calcium on Lipid-Protein Interactions and Ion Flux in the Cx26 Connexon Embedded into a POPC Bilayer.
Topics: Calcium; Connexin 26; Connexins; Humans; Hydrogen Bonding; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines | 2019 |
Modulation of membrane permeability by carbon dioxide.
Topics: Carbon Dioxide; Cell Membrane; Dideoxyadenosine; Ethanol; Lipid Bilayers; Molecular Dynamics Simulation; Permeability; Phosphatidylcholines; Trimethoprim | 2020 |
Fibrillation of human islet amyloid polypeptide and its toxicity to pancreatic β-cells under lipid environment.
Topics: Amyloid; Apoptosis; Cell Membrane; Endoplasmic Reticulum Stress; Fatty Acids, Nonesterified; Fibrosis; Gene Expression Regulation; Humans; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Lipid Metabolism; Lipids; Palmitic Acid; Phosphatidylcholines; Phosphatidylserines; Protein Conformation, beta-Strand; Protein Folding | 2020 |
Understanding toward the Biophysical Interaction of Polymeric Proanthocyanidins (Persimmon Condensed Tannins) with Biomembranes: Relevance for Biological Effects.
Topics: Animals; Biophysical Phenomena; Cell Membrane; Cholesterol; Diospyros; Fruit; Membrane Fluidity; Mice; NIH 3T3 Cells; Phosphatidylcholines; Plant Extracts; Polymerization; Proanthocyanidins; Sphingomyelins | 2019 |
Effect of oxidative stress on cystine transportation by xC‾ antiporter.
Topics: Amino Acid Transport System y+; Antiporters; Biological Transport; Cysteine; Cystine; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Oxidation-Reduction; Phosphatidylcholines; Protein Conformation; Thermodynamics | 2019 |
Chirality-Dependent Adsorption between Amphipathic Peptide and POPC Membrane.
Topics: Adsorption; Amino Acid Sequence; Antimicrobial Cationic Peptides; Lipid Bilayers; Molecular Conformation; Molecular Dynamics Simulation; Phosphatidylcholines | 2019 |
Phospholipid Scramblases Remodel the Shape of Asymmetric Membranes.
Topics: Fungal Proteins; Lipid Bilayers; Molecular Dynamics Simulation; Nectria; Phosphatidylcholines; Phospholipid Transfer Proteins | 2019 |
AMPA Receptor Noncompetitive Inhibitors Occupy a Promiscuous Binding Site.
Topics: Animals; Binding Sites; Membranes, Artificial; Molecular Docking Simulation; Molecular Dynamics Simulation; Phosphatidylcholines; Receptors, AMPA; Water | 2019 |
G-Protein-Coupled Receptor-Membrane Interactions Depend on the Receptor Activation State.
Topics: Binding Sites; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Receptors, G-Protein-Coupled | 2020 |
Lipid Membranes Influence the Ability of Small Molecules To Inhibit Huntingtin Fibrillization.
Topics: Amyloidogenic Proteins; Catechin; Curcumin; Humans; Huntingtin Protein; Liposomes; Phosphatidylcholines; Protein Multimerization | 2019 |
Deciphering the Peculiar Behavior of β-Lapachone in Lipid Monolayers and Bilayers.
Topics: Lipid Bilayers; Naphthoquinones; Particle Size; Phosphatidylcholines; Surface Properties | 2019 |
Counter-effects of Ethanol and Cholesterol on the Heterogeneous PSM-POPC Lipid Membrane: A Molecular Dynamics Simulation Study.
Topics: Cholesterol; Ethanol; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Sphingomyelins; Water | 2019 |
Evaluation of Cyclic Peptide Inhibitors of the Grb7 Breast Cancer Target: Small Change in Cargo Results in Large Change in Cellular Activity.
Topics: Amino Acid Sequence; Antineoplastic Agents; Binding Sites; Cell Line; Cell Line, Tumor; Cell Membrane Permeability; Cell Movement; Cell Proliferation; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; GRB7 Adaptor Protein; Humans; Lipid Bilayers; Peptides, Cyclic; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Proto-Oncogene Proteins c-akt; Signal Transduction; src Homology Domains; Structure-Activity Relationship | 2019 |
Molecular dynamics simulations of mechanical stress on oxidized membranes.
Topics: Lipid Bilayers; Molecular Dynamics Simulation; Oxidation-Reduction; Phosphatidylcholines | 2019 |
Effect of selected B-ring-substituted oxysterols on artificial model erythrocyte membrane and isolated red blood cells.
Topics: Cell Shape; Cells, Cultured; Elasticity; Erythrocyte Membrane; Erythrocytes; Humans; Hydroxycholesterols; Ketocholesterols; Membrane Fluidity; Membranes, Artificial; Oxysterols; Phosphatidylcholines | 2020 |
Morphology and dynamics of domains in ergosterol or cholesterol containing membranes.
Topics: Cholesterol; Ergosterol; Lipid Bilayers; Membrane Microdomains; Phosphatidylcholines; Sphingomyelins; Unilamellar Liposomes | 2020 |
Cholesteryl Hemisuccinate Is Not a Good Replacement for Cholesterol in Lipid Nanodiscs.
Topics: Cholesterol; Cholesterol Esters; Lipid Bilayers; Molecular Dynamics Simulation; Nanostructures; Phosphatidylcholines; Phosphatidylglycerols | 2019 |
The influence of cationic lipoid - 1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine - on model lipid membranes.
Topics: Cations; Cell Membrane Permeability; Cholesterol; Drug Delivery Systems; Membrane Fluidity; Membrane Lipids; Membranes, Artificial; Phosphatidylcholines; Sphingomyelins | 2020 |
Clustering and dynamics of crowded proteins near membranes and their influence on membrane bending.
Topics: Bacterial Proteins; Cell Membrane; Cluster Analysis; Diffusion; Lipid Bilayers; Microfilament Proteins; Molecular Dynamics Simulation; Phosphatidylcholines; Proteins; Sphingomyelins; Ubiquitin | 2019 |
Peptide Disc Mediated Control of Membrane Protein Orientation in Supported Lipid Bilayers for Surface-Sensitive Investigations.
Topics: Aluminum Silicates; Cation Transport Proteins; Gold; Humans; Lipid Bilayers; Peptides; Phosphatidylcholines; Phosphatidylserines; Recombinant Proteins; Silicon Dioxide; Thromboplastin | 2020 |
A molecular dynamics study proposing the existence of statistical structural heterogeneity due to chain orientation in the POPC-cholesterol bilayer.
Topics: Cholesterol; Lipid Bilayers; Microscopy, Atomic Force; Molecular Dynamics Simulation; Phase Transition; Phosphatidylcholines; Temperature | 2020 |
Interactions of Ionic Liquids and Spirocyclic Compounds with Liposome Model Membranes. A Steady-State Fluorescence Anisotropy Study.
Topics: Biomimetics; Cholesterol; Diphenylhexatriene; Fluorescence Polarization; Green Chemistry Technology; Ionic Liquids; Lipid Bilayers; Liposomes; Membranes; Phosphatidylcholines; Phosphatidylserines; Surface-Active Agents | 2019 |
Structural evolution of supported lipid bilayers intercalated with quantum dots.
Topics: Lipid Bilayers; Models, Chemical; Phosphatidylcholines; Phosphatidylethanolamines; Quantum Dots | 2020 |
Biodegradable hybrid block copolymer - lipid vesicles as potential drug delivery systems.
Topics: Fluoresceins; Humans; Liposomes; Phosphatidylcholines; Polyesters; Polyethylene Glycols | 2020 |
DMSO induced dehydration of heterogeneous lipid bilayers and its impact on their structures.
Topics: Dehydration; Dimethyl Sulfoxide; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Structure; Phosphatidylcholines; Sphingomyelins | 2019 |
Intracellular Vesicle Fusion Requires a Membrane-Destabilizing Peptide Located at the Juxtamembrane Region of the v-SNARE.
Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans; Cell Membrane; Drosophila melanogaster; Humans; Lipid Bilayers; Membrane Fusion; Mice; Models, Molecular; Munc18 Proteins; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Sequence Alignment; Sequence Homology, Amino Acid; SNARE Proteins; Synaptosomal-Associated Protein 25; Transport Vesicles; Vesicle-Associated Membrane Protein 2; Xenopus laevis | 2019 |
Computational Design of Biologically Active Anticancer Peptides and Their Interactions with Heterogeneous POPC/POPS Lipid Membranes.
Topics: Antineoplastic Agents; Cell Line, Tumor; Computer Simulation; Drug Design; Humans; Membrane Lipids; Molecular Dynamics Simulation; Peptides; Phosphatidylcholines; Phosphatidylserines | 2020 |
How is the interaction of a chloride channel blocker with phospholipids influenced by divalent metal ions? Effect of unsaturation on the lipid side chain.
Topics: Anthracenes; Calcium; Cations, Divalent; Dimyristoylphosphatidylcholine; Liposomes; Magnesium; Particle Size; Phosphatidylcholines; Surface Properties; Zinc | 2020 |
How Do Ethanolamine Plasmalogens Contribute to Order and Structure of Neurological Membranes?
Topics: Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Plasmalogens; Thermodynamics | 2020 |
The role of electrostatic potential polarization in the translocation of graphene quantum dots across membranes.
Topics: Adsorption; Carbon; Computer Simulation; Graphite; Hydrogen; Membranes; Nanostructures; Nanotechnology; Phosphatidylcholines; Quantum Dots; Static Electricity; Surface Properties; Thermodynamics; Water | 2020 |
Revisiting the Interaction of Melittin with Phospholipid Bilayers: The Effects of Concentration and Ionic Strength.
Topics: Anti-Infective Agents; Kinetics; Lipid Bilayers; Liposomes; Melitten; Models, Chemical; Osmolar Concentration; Phosphatidylcholines; Phospholipids; Surface Plasmon Resonance | 2020 |
Conformational changes upon gating of KirBac1.1 into an open-activated state revealed by solid-state NMR and functional assays.
Topics: Bacterial Proteins; Catalytic Domain; Fluorescence Resonance Energy Transfer; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Phosphatidylcholines; Phosphatidylglycerols; Potassium; Potassium Channels, Inwardly Rectifying; Protein Conformation; Protein Domains; Protein Structure, Secondary | 2020 |
Lipid dynamics in nanoparticles formed by maleic acid-containing copolymers: EPR spectroscopy and molecular dynamics simulations.
Topics: Alkenes; Dimyristoylphosphatidylcholine; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Maleates; Membrane Proteins; Molecular Dynamics Simulation; Nanoparticles; Phosphatidylcholines; Phospholipids; Polymers; Polystyrenes; Spin Labels | 2020 |
Equilibrium penetration of pluronic F-68 in lipid monolayers.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; CHO Cells; Cricetinae; Cricetulus; Phosphatidylcholines; Poloxamer; Thermodynamics | 2020 |
Structural Basis for Lipid Binding and Function by an Evolutionarily Conserved Protein, Serum Amyloid A.
Topics: Animals; Binding Sites; Hydrophobic and Hydrophilic Interactions; Ligands; Mice; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Conformation; Protein Folding; Serum Amyloid A Protein | 2020 |
Interpretation of the molecular mechanism of the electroporation induced by symmetrical bipolar picosecond pulse trains.
Topics: Cell Membrane; Electricity; Electroporation; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines | 2020 |
Structural Analysis and Design of Chionodracine-Derived Peptides Using Circular Dichroism and Molecular Dynamics Simulations.
Topics: Amino Acid Sequence; Animals; Anisotropy; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Circular Dichroism; Lipid Bilayers; Membranes, Artificial; Molecular Dynamics Simulation; Perciformes; Phosphatidylcholines; Protein Conformation, alpha-Helical; Water | 2020 |
Interaction of Camptothecin with Model Cellular Membranes.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Membrane; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Models, Molecular; Phosphatidylcholines | 2020 |
Design and synthesis of a novel peptide for selective detection of cancer cells.
Topics: Amino Acid Sequence; CD13 Antigens; Cell Line, Tumor; Flow Cytometry; Fluorescent Dyes; Humans; Hydrophobic and Hydrophilic Interactions; Integrins; Lipid Bilayers; Optical Imaging; Peptides; Phosphatidylcholines; Protein Structure, Secondary; Rhodamines; Structure-Activity Relationship; Substrate Specificity; Unilamellar Liposomes | 2020 |
Geochemical influences on nonenzymatic oligomerization of prebiotically relevant cyclic nucleotides.
Topics: Cyclic AMP; Cyclic CMP; Hot Springs; Hot Temperature; Phosphatidylcholines; Water | 2020 |
Graphene-extracted membrane lipids facilitate the activation of integrin α
Topics: Amino Acid Sequence; Binding Sites; Graphite; Hydrophobic and Hydrophilic Interactions; Integrins; Lipid Bilayers; Membrane Fluidity; Molecular Dynamics Simulation; Nanostructures; Phosphatidylcholines; Protein Domains | 2020 |
Investigating matrix effects of different combinations of lipids and peptides on TOF-SIMS data.
Topics: Angiotensin II; Enkephalin, Leucine; Lipids; Peptides; Phosphatidylcholines; Spectrometry, Mass, Secondary Ion | 2020 |
Hybrid giant lipid vesicles incorporating a PMMA-based copolymer.
Topics: Lipids; Liposomes; Methacrylates; Particle Size; Phase Transition; Phosphatidylcholines; Polyethylene Glycols; Polymethyl Methacrylate; Transition Temperature | 2021 |
Effect of Electrical Parameters and Cholesterol Concentration on Giant Unilamellar Vesicles Electroformation.
Topics: Cell Membrane; Cholesterol; Humans; Lens, Crystalline; Lipid Bilayers; Lipids; Microscopy, Fluorescence; Phosphatidylcholines; Phospholipids; Solubility; Solvents; Temperature; Unilamellar Liposomes | 2020 |
Distinct classes of multi-subunit heterogeneity: analysis using Fourier Transform methods and native mass spectrometry.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Fourier Analysis; Mass Spectrometry; Membrane Proteins; Nanostructures; Phosphatidylcholines; Polyethylene Glycols; Propylene Glycols; Protein Subunits | 2020 |
Membrane affinity of individual toxic protein oligomers determined at the single-molecule level.
Topics: Cholesterol; Humans; Islet Amyloid Polypeptide; Lipid Bilayers; Phosphatidylcholines; Phosphatidylglycerols; Photobleaching; Protein Multimerization; Protein Structure, Quaternary; Rhodamines; Single Molecule Imaging | 2020 |
Cholesterol-mediated oligomerization pathways of serotonin G-coupled receptor 5-HT2C.
Topics: Cholesterol; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Domains; Protein Multimerization; Receptor, Serotonin, 5-HT2C | 2020 |
Delivery of Alpha-Mangostin Using Cyclodextrins through a Biological Membrane: Molecular Dynamics Simulation.
Topics: Adsorption; beta-Cyclodextrins; Drug Carriers; Drug Design; Hydrogen Bonding; Lipid Bilayers; Lipids; Molecular Dynamics Simulation; Permeability; Phosphatidylcholines; Solubility; Static Electricity; Xanthones | 2020 |
Sensitive Morphological Characterization of Oriented High-Density Lipoprotein Nanoparticles Using
Topics: Cholesterol; Lipoproteins, HDL; Magnetic Resonance Spectroscopy; Microscopy, Electron, Transmission; Nanoparticles; Phosphatidylcholines; Phosphorus Isotopes | 2020 |
Membrane determinants for the passive translocation of analytes through droplet interface bilayers.
Topics: Caco-2 Cells; Cell Membrane; Fluorescent Dyes; Humans; Lipid Bilayers; Oils; Permeability; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Water | 2020 |
Oxidation of Polyunsaturated Lipid Membranes by Photocatalytic Titanium Dioxide Nanoparticles: Role of pH and Salinity.
Topics: Catalysis; Hydrogen-Ion Concentration; Lipid Bilayers; Nanoparticles; Oxidation-Reduction; Particle Size; Phosphatidylcholines; Photochemical Processes; Salinity; Surface Properties; Titanium | 2020 |
Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery.
Topics: Amino Acid Sequence; Autophagy; Autophagy-Related Proteins; Cryoelectron Microscopy; HEK293 Cells; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Membrane Proteins; Molecular Dynamics Simulation; Mutagenesis; Phosphatidylcholines; Protein Domains; Protein Multimerization; Protein Structure, Secondary; Protein Subunits; Vesicular Transport Proteins | 2020 |
Insight into the structure-antibacterial activity of amino cation-based and acetate anion-based ionic liquids from computational interactions with the POPC phospholipid bilayer.
Topics: Anti-Bacterial Agents; Ionic Liquids; Lipid Bilayers; Molecular Dynamics Simulation; Molecular Structure; Phosphatidylcholines | 2020 |
Development of a Microfluidic-Based Post-Treatment Process for Size-Controlled Lipid Nanoparticles and Application to siRNA Delivery.
Topics: Animals; Cholesterol; Factor VII; Hepatocytes; Lipids; Mice; Mice, Inbred ICR; Microfluidics; Microscopy, Confocal; Nanoparticles; Phosphatidylcholines; RNA Interference; RNA, Small Interfering; Transfection | 2020 |
Penetratin translocation mechanism through asymmetric droplet interface bilayers.
Topics: Cell-Penetrating Peptides; Lipid Bilayers; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylserines | 2020 |
Complexity of seemingly simple lipid nanodiscs.
Topics: Dimyristoylphosphatidylcholine; Molecular Dynamics Simulation; Nanostructures; Phosphatidylcholines | 2020 |
Lipid selectivity in detergent extraction from bilayers.
Topics: Detergents; Lipid Bilayers; Lipids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols | 2020 |
Normalizing polydiacetylene colorimetric assays of vesicle binding across lipid systems.
Topics: Amyloid beta-Peptides; Colorimetry; Lipid Bilayers; Phosphatidylcholines; Phosphatidylethanolamines; Polyacetylene Polymer | 2020 |
β-Amyloid (1-42) peptide adsorbs but does not insert into ganglioside-containing phospholipid membranes in the liquid-disordered state: modelling and experimental studies.
Topics: Adsorption; Amyloid beta-Peptides; Benzothiazoles; Calorimetry; Cell Membrane; G(M1) Ganglioside; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Peptide Fragments; Phosphatidylcholines | 2020 |
Thermally induced structural organization of nanodiscs by coarse-grained molecular dynamics simulations.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Nanostructures; Phosphatidylcholines; Temperature | 2020 |
Thermodynamic quantification of sodium dodecyl sulfate penetration in cholesterol and phospholipid monolayers.
Topics: Adsorption; Cholesterol; Phosphatidylcholines; Phospholipids; Pressure; Sodium Dodecyl Sulfate; Surface Properties; Thermodynamics | 2020 |
Selective regulation of human TRAAK channels by biologically active phospholipids.
Topics: Adenosine; Cations, Monovalent; Cloning, Molecular; Gene Expression; Genetic Vectors; Glycerophospholipids; Humans; Ion Channel Gating; Ion Transport; Kinetics; Liposomes; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Phosphatidylserines; Pichia; Potassium; Potassium Channels; Protein Binding; Protein Isoforms; Recombinant Proteins | 2021 |
Membrane Interaction of Ibuprofen with Cholesterol-Containing Lipid Membranes.
Topics: Cholesterol; Ibuprofen; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Unilamellar Liposomes | 2020 |
Atomistic Structure and Dynamics of the Ca
Topics: Allosteric Regulation; Binding Sites; Calcium-Binding Proteins; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phosphorylation; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine; Thermodynamics | 2020 |
Lipid-bound ApoE3 self-assemble into elliptical disc-shaped particles.
Topics: Apolipoprotein E3; Dimyristoylphosphatidylcholine; Humans; Lipid Bilayers; Phosphatidylcholines | 2021 |
Coarse-grained implicit solvent lipid force field with a compatible resolution to the Cα protein representation.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Lipid Bilayers; Membrane Lipids; Membrane Proteins; Models, Chemical; Molecular Dynamics Simulation; Phosphatidylcholines | 2020 |
Prebiotic Peptide Synthesis and Spontaneous Amyloid Formation Inside a Proto-Cellular Compartment.
Topics: Amino Acids; Amyloidogenic Proteins; Decanoic Acids; Liposomes; Oleic Acid; Origin of Life; Peptides; Permeability; Phosphatidylcholines; Protein Multimerization | 2021 |
Ligand based conformational space studies of the μ-opioid receptor.
Topics: Amino Acids; Apoproteins; Binding Sites; Humans; Ligands; Lipid Bilayers; Molecular Docking Simulation; Molecular Dynamics Simulation; Morphinans; Morphine; Naloxone; Phosphatidylcholines; Protein Binding; Protein Conformation, alpha-Helical; Pyrroles; Receptors, Opioid, mu; Solutions; Water | 2021 |
Effect of Amyloid-β Monomers on Lipid Membrane Mechanical Parameters-Potential Implications for Mechanically Driven Neurodegeneration in Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Brain; Cell Membrane; Humans; Lipid Bilayers; Membrane Lipids; Membrane Potentials; Microscopy, Confocal; Molecular Dynamics Simulation; Neurodegenerative Diseases; Neurons; Peptide Fragments; Phosphatidylcholines | 2020 |
Cholesterol content in the membrane promotes key lipid-protein interactions in a pentameric serotonin-gated ion channel.
Topics: Animals; Cell Membrane; Cholesterol; Membrane Lipids; Mice; Molecular Dynamics Simulation; Phosphatidylcholines; Phosphatidylethanolamines; Protein Binding; Protein Domains; Receptors, Serotonin, 5-HT3 | 2021 |
DNA origami demonstrate the unique stimulatory power of single pMHCs as T cell antigens.
Topics: Animals; Antigen-Presenting Cells; CD4-Positive T-Lymphocytes; DNA; Gene Expression; Ligands; Lipid Bilayers; Lymphocyte Activation; Major Histocompatibility Complex; Mice; Nucleic Acid Conformation; Phosphatidylcholines; Primary Cell Culture; Protein Binding; Receptors, Antigen, T-Cell; Signal Transduction; Single-Chain Antibodies; Spleen | 2021 |
Molecular insights into MXene destructing the cell membrane as a "nano thermal blade".
Topics: Cell Membrane; Heating; Molecular Dynamics Simulation; Nanostructures; Phosphatidylcholines; Temperature; Titanium | 2021 |
Diethylstilbestrol Modifies the Structure of Model Membranes and Is Localized Close to the First Carbons of the Fatty Acyl Chains.
Topics: Calorimetry, Differential Scanning; Carbon; Diethylstilbestrol; Fatty Acids; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membranes, Artificial; Molecular Dynamics Simulation; Phase Transition; Phosphatidylcholines; Phospholipids; Phosphorus Radioisotopes; Protons; Solubility; Temperature; Thermodynamics; X-Ray Diffraction | 2021 |
Shape changes and budding of giant vesicles induced by an internal chemical trigger: an interplay between osmosis and pH change.
Topics: Hydrogen-Ion Concentration; Oleic Acid; Osmosis; Phosphatidylcholines; Unilamellar Liposomes; Urea; Urease | 2021 |
Substrate-dependent arrangements of the subunits of the BAM complex determined by neutron reflectometry.
Topics: Lipoproteins; Neutron Diffraction; Phosphatidylcholines; Quartz Crystal Microbalance Techniques | 2021 |
Tylopeptin B peptide antibiotic in lipid membranes at low concentrations: Self-assembling, mutual repulsion and localization.
Topics: Anti-Bacterial Agents; Electron Spin Resonance Spectroscopy; Peptaibols; Phosphatidylcholines | 2021 |
Investigation of the domain line tension in asymmetric vesicles prepared via hemifusion.
Topics: Cholesterol; Phosphatidylcholines; Surface Tension; Unilamellar Liposomes | 2021 |
Effect of Aminated Chitosan-Coated Fe
Topics: Amines; Animals; Cell Membrane; Chitosan; Ferric Compounds; Humans; Kinetics; Models, Biological; Nanomedicine; Nanoparticles; Phosphatidylcholines; Phosphatidylglycerols; Surface Properties | 2021 |
Insights into the Action Mechanism of the Antimicrobial Peptide Lasioglossin III.
Topics: Animals; Antimicrobial Cationic Peptides; Bees; Calorimetry; Cell Membrane; Cell Membrane Permeability; Gram-Negative Bacteria; Gram-Positive Bacteria; Lipid Bilayers; Liposomes; Phosphatidylcholines; Phosphatidylglycerols; Pore Forming Cytotoxic Proteins; Spectrophotometry | 2021 |
Can di-4-ANEPPDHQ reveal the structural differences between nanodiscs and liposomes?
Topics: Fluorescent Dyes; Liposomes; Molecular Dynamics Simulation; Molecular Structure; Nanoparticles; Phosphatidylcholines; Phosphatidylglycerols; Pyridinium Compounds; Spectrometry, Fluorescence | 2021 |
Molecular organization in hydroperoxidized POPC bilayers.
Topics: Hydrogen Peroxide; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Oxidation-Reduction; Phosphatidylcholines; Spectrometry, Fluorescence | 2021 |
Dissociation of Biomolecules by an Intense Low-Energy Electron Beam in a High Sensitivity Time-of-Flight Mass Spectrometer.
Topics: Biological Products; Carbonic Anhydrase II; Egg Yolk; Electrons; Equipment Design; Glycopeptides; Ions; Phosphatidylcholines; Proteins; Sensitivity and Specificity; Serum Albumin, Bovine; Tandem Mass Spectrometry; Ubiquitin | 2021 |
Chiral lipid bilayers are enantioselectively permeable.
Topics: Alkynes; Amino Acids; Cholesterol; Fluorescent Dyes; Lipid Bilayers; Permeability; Phosphatidylcholines; Stereoisomerism | 2021 |
Effect of cholesterol on the dimerization of C99-A molecular modeling perspective.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Binding Sites; Cholesterol; Dimerization; Humans; Lipid Bilayers; Molecular Dynamics Simulation; Peptide Fragments; Phosphatidylcholines | 2021 |
Impact of Doping a Phytosteryl Sulfate on the Properties of Liposomes Made of Saturated and Unsaturated Phosphatidylcholines.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Glucose; Liposomes; Membrane Fluidity; Molecular Structure; Particle Size; Phosphatidylcholines; Sitosterols; Static Electricity | 2021 |
Unravelling Melatonin's Varied Antioxidizing Protection of Membrane Lipids Determined by its Spatial Distribution.
Topics: Antioxidants; Hydroxyl Radical; Mass Spectrometry; Melatonin; Molecular Structure; Phosphatidylcholines | 2021 |
Improving the accuracy and convergence of drug permeation simulations via machine-learned collective variables.
Topics: Algorithms; Cholesterol; Lipid Bilayers; Molecular Dynamics Simulation; Pharmacokinetics; Phosphatidylcholines; Thermodynamics; Trimethoprim; Unsupervised Machine Learning | 2021 |
A multiscale approach for bridging the gap between potency, efficacy, and safety of small molecules directed at membrane proteins.
Topics: Animals; Enzyme Activation; Giant Cells; Humans; Induced Pluripotent Stem Cells; Membrane Proteins; Microsomes; Molecular Dynamics Simulation; Molecular Structure; Molecular Targeted Therapy; Myocytes, Cardiac; Phosphatidylcholines; Protein Domains; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Small Molecule Libraries; Swine; Water | 2021 |
Cholesterol plays a decisive role in tetraspanin assemblies during bilayer deformations.
Topics: Algorithms; Cell Membrane; Cholesterol; Humans; Lipid Bilayers; Membrane Microdomains; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Binding; Protein Conformation; Tetraspanin 28; Thermodynamics | 2021 |
Potential Anti-Alzheimer Agents from Guanidinyl Tryptophan Derivatives with Activities of Membrane Adhesion and Conformational Transition Inhibitions.
Topics: Adhesiveness; Adsorption; Alzheimer Disease; Amyloid beta-Peptides; Cell Membrane; Guanidine; Humans; Ligands; Lipid Bilayers; Lipids; Models, Molecular; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Conformation; Protein Structure, Secondary; Tryptophan; Water | 2021 |
Inverse Conformational Selection in Lipid-Protein Binding.
Topics: Lipids; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Proteins | 2021 |
The impact of fluoxetine and pH values on relaxation of the ternary lipid monolayers.
Topics: Cholesterol; Fluoxetine; Hydrogen-Ion Concentration; Lipids; Microscopy, Atomic Force; Phosphatidylcholines; Thermodynamics | 2021 |
Gangliosides smelt nanostructured amyloid Aβ(1-40) fibrils in a membrane lipid environment.
Topics: Amyloid; Amyloid beta-Peptides; Gangliosides; Glycosphingolipids; Membrane Lipids; Microscopy, Atomic Force; Nanostructures; Peptide Fragments; Phosphatidylcholines; Surface Properties | 2022 |
Clotrimazole Fluidizes Phospholipid Membranes and Localizes at the Hydrophobic Part near the Polar Part of the Membrane.
Topics: Calorimetry, Differential Scanning; Cell Membrane; Clotrimazole; Dimyristoylphosphatidylcholine; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Membrane Fluidity; Molecular Dynamics Simulation; Phosphatidylcholines; Phospholipids; Proton Magnetic Resonance Spectroscopy; Temperature; Water | 2021 |
Tau fibril with membrane lipids: Insight from computational modeling and simulations.
Topics: Cholesterol; Humans; Membrane Lipids; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Phosphatidylcholines; Protein Structure, Secondary; Sphingomyelins; tau Proteins | 2021 |
Phospholipids dock SARS-CoV-2 spike protein via hydrophobic interactions: a minimal in-silico study of lecithin nasal spray therapy.
Topics: Binding Sites; Hydrophobic and Hydrophilic Interactions; Lecithins; Molecular Docking Simulation; Nasal Sprays; Phosphatidylcholines; Protein Binding; Spike Glycoprotein, Coronavirus; Surface-Active Agents | 2021 |
Synthesis and Characterization of Multifunctional Nanovesicles Composed of POPC Lipid Molecules for Nuclear Imaging.
Topics: Drug Carriers; Drug Delivery Systems; Hydrophobic and Hydrophilic Interactions; Liposomes; Molecular Structure; Nanomedicine; Nanoparticles; Neutron Diffraction; Phosphatidylcholines; Scattering, Small Angle | 2021 |
Lipid saturation and head group composition have a pronounced influence on the membrane insertion equilibrium of amphipathic helical polypeptides.
Topics: Amino Acid Sequence; Antimicrobial Cationic Peptides; Dimyristoylphosphatidylcholine; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Magainins; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylglycerols | 2022 |
Anti-steroidogenic effects of cholesterol hydroperoxide trafficking in MA-10 Leydig cells: Role of mitochondrial lipid peroxidation and inhibition thereof by selenoperoxidase GPx4.
Topics: Animals; Carbolines; Cell Death; Cell Line, Tumor; Cholesterol; Fluorescence; Isoindoles; Leydig Cells; Lipid Peroxidation; Male; Mice; Mitochondria; Mitochondrial Membranes; Organoselenium Compounds; Phosphatidylcholines; Phospholipid Hydroperoxide Glutathione Peroxidase; Progesterone; Protective Agents; Steroids | 2022 |
H1 helix of colicin U causes phospholipid membrane permeation.
Topics: Amino Acid Sequence; Colicins; Molecular Dynamics Simulation; Permeability; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Conformation, alpha-Helical; Shigella boydii; Unilamellar Liposomes | 2022 |
A method to construct the dynamic landscape of a bio-membrane with experiment and simulation.
Topics: Buffers; Carbon Isotopes; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membranes, Artificial; Molecular Dynamics Simulation; Motion; Phosphatidylcholines; Solutions | 2022 |
Ion currents through Kir potassium channels are gated by anionic lipids.
Topics: Anions; Binding Sites; Crystallography, X-Ray; Humans; Ion Channel Gating; Ion Transport; Liposomes; Membrane Lipids; Molecular Dynamics Simulation; Mutation; Phosphatidylcholines; Phosphatidylserines; Potassium; Potassium Channels, Inwardly Rectifying | 2022 |
Characterization of phase separation phenomena in hybrid lipid/block copolymer/cholesterol bilayers using laurdan fluorescence with log-normal multipeak analysis.
Topics: Cholesterol; Microscopy, Fluorescence; Phase Transition; Phosphatidylcholines; Polymers; Spectrometry, Fluorescence; Sphingomyelins; Transition Temperature; Unilamellar Liposomes | 2022 |
Structure of POPC Lipid Bilayers in OPLS3e Force Field.
Topics: Hydrogen; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines | 2022 |
Quantitative Comparison against Experiments Reveals Imperfections in Force Fields' Descriptions of POPC-Cholesterol Interactions.
Topics: Cholesterol; Lipid Bilayers; Molecular Dynamics Simulation; Phosphatidylcholines | 2023 |