Page last updated: 2024-08-21

phorone and diethyl maleate

phorone has been researched along with diethyl maleate in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199017 (51.52)18.7374
1990's13 (39.39)18.2507
2000's3 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koster, AS; Moison, RM; Noordhoek, J; Redegeld, FA1
Dahm, LJ; Roth, RA1
Bauman, JW; Klaassen, CD; Liu, J; Liu, YP1
Gullberg, D; Högberg, J; Rubin, K; Stenius, U1
Bates, HK; Casciano, DA; Gandy, J; Harbison, RD; Millner, GC1
Nederbragt, H1
Arslan, P; Beltrame, M; Tomasi, A1
Masukawa, T; Sai, M; Tochino, Y1
Gregus, Z; Howell, S; Klaassen, CD; White, C1
Bhatt, HS; Combes, B; Lober, SB1
Mandel, LJ; Schnellmann, RG1
Costa, LG; Murphy, SD1
Cederbaum, AI; Dicker, E2
Iwata, H; Masukawa, T1
Romero, FJ; Sáez, GT; Viña, J1
Adams, GE1
Strubelt, O; Younes, M1
Iwata, H; Masukawa, T; Nishimura, T1
Dudley, RE; Klaassen, CD1
Reiter, R; Wendel, A1
Bend, JR; Plummer, JL; Sies, H; Smith, BR1
Haddock, PS; Hearse, DJ; Woodward, B1
Awad, JA; Burk, RF; Hill, KE; Lyons, PR; Morrow, JD1
Borroz, KI; Buetler, TM; Eaton, DL1
Allen, KG; Bottje, WG; Enkvetchakul, B; Graupner, WG1
Timbrell, JA; Waterfield, CJ1
Klein, D; Lichtmannegger, J; Summer, KH; Wolff, T1
Furusho, A; Nakahara, T; Numazawa, S; Oguro, T; Yamada, H; Yoshida, T1
Agarwal, R; Shukla, GS1
Datta, M; Gupta, A; Shukla, GS1
Bortolato, S; Ferrara, R; Manno, M; White, IN; Zanovello, A1
Feng, G; Kaplowitz, N; Matsumaru, K; Nagai, H1

Reviews

1 review(s) available for phorone and diethyl maleate

ArticleYear
Chemical depletion of glutathione in vivo.
    Methods in enzymology, 1981, Volume: 77

    Topics: Animals; Brain; Cytochrome P-450 Enzyme System; Diamide; Erythrocytes; Ethylmorphine; Fasting; Glutathione; Glutathione Disulfide; Glutathione Transferase; Glycylglycine; Ketones; Kidney; Lipid Metabolism; Liver; Maleates; Oxidation-Reduction; Oxygenases; Sulfhydryl Compounds; Tetrathionic Acid

1981

Other Studies

32 other study(ies) available for phorone and diethyl maleate

ArticleYear
Depletion of ATP but not of GSH affects viability of rat hepatocytes.
    European journal of pharmacology, 1992, Dec-01, Volume: 228, Issue:4

    Topics: Adenosine Triphosphate; Animals; Cell Survival; Dose-Response Relationship, Drug; Ethacrynic Acid; Glutathione; Ketones; Liver; Male; Maleates; Potassium Cyanide; Rats; Rats, Wistar

1992
Protection against alpha-naphthylisothiocyanate-induced liver injury by decreased hepatic non-protein sulfhydryl content.
    Biochemical pharmacology, 1991, Aug-22, Volume: 42, Issue:6

    Topics: 1-Naphthylisothiocyanate; Animals; Aspartate Aminotransferases; Bile; Bile Acids and Salts; Bilirubin; Buthionine Sulfoximine; Cholestasis, Intrahepatic; gamma-Glutamyltransferase; Glutathione; Ketones; Liver; Male; Maleates; Methionine Sulfoximine; Rats; Rats, Inbred Strains

1991
Increase in metallothionein produced by chemicals that induce oxidative stress.
    Toxicology and applied pharmacology, 1991, Sep-01, Volume: 110, Issue:2

    Topics: Animals; Cisplatin; Cytosol; Diamide; Diquat; Doxorubicin; Ketones; Liver; Male; Maleates; Metallothionein; Metronidazole; Mice; Mice, Inbred Strains; Organ Specificity; Paraquat; Peroxides; Skatole; tert-Butylhydroperoxide; Vitamin K

1991
gamma-Glutamyltranspeptidase-positive rat hepatocytes are protected from GSH depletion, oxidative stress and reversible alterations of collagen receptors.
    Carcinogenesis, 1990, Volume: 11, Issue:1

    Topics: Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cells, Cultured; Collagen; Diethylnitrosamine; Diquat; Female; gamma-Glutamyltransferase; Glutathione; Hydrogen Peroxide; Hydroquinones; Ketones; Kinetics; Liver; Maleates; Phenobarbital; Rats; Receptors, Cell Surface; Receptors, Collagen; Selenium; Sodium Selenite; Vitamin K

1990
Effects of selected chemicals on the glutathione status in the male reproductive system of rats.
    Journal of toxicology and environmental health, 1990, Volume: 29, Issue:1

    Topics: Animals; Cyclohexanes; Cyclohexanones; Epididymis; Glutathione; Hydrocarbons, Iodinated; Ketones; Male; Maleates; Naphthalenes; Organophosphates; Rats; Rats, Inbred Strains; Testis

1990
Effect of the glutathione-depleting agents diethylmaleate, phorone and buthionine sulfoximine on biliary copper excretion in rats.
    Biochemical pharmacology, 1989, Oct-15, Volume: 38, Issue:20

    Topics: Animals; Bile; Buthionine Sulfoximine; Copper; Glutathione; Ketones; Male; Maleates; Methionine Sulfoximine; Rats; Rats, Inbred Strains

1989
Intracellular chromium reduction.
    Biochimica et biophysica acta, 1987, Oct-22, Volume: 931, Issue:1

    Topics: Animals; Cell Membrane; Chromates; Chromium; Electron Spin Resonance Spectroscopy; Intracellular Fluid; Ketones; Maleates; Oxidation-Reduction; Rats; Rats, Inbred Strains; Thymus Gland

1987
Methods for depleting brain glutathione.
    Life sciences, 1989, Volume: 44, Issue:6

    Topics: Animals; Brain; Cycloheptanes; Cyclohexanones; Dose-Response Relationship, Drug; Glutathione; Injections, Intraventricular; Ketones; Kinetics; Male; Maleates; Mice; Mice, Inbred ICR

1989
Effect of glutathione depletion on sulfate activation and sulfate ester formation in rats.
    Biochemical pharmacology, 1988, Nov-15, Volume: 37, Issue:22

    Topics: Animals; Dichloroethylenes; Glutathione; Harmine; Ketones; Liver; Male; Maleates; Phosphoadenosine Phosphosulfate; Rats; Rats, Inbred Strains; Sulfates

1988
Effect of glutathione depletion on aminopyrine and formaldehyde metabolism.
    Biochemical pharmacology, 1988, Apr-15, Volume: 37, Issue:8

    Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Breath Tests; Buthionine Sulfoximine; Formaldehyde; Formates; Glutathione; Ketones; Male; Maleates; Methionine Sulfoximine; Microsomes, Liver; Rats; Rats, Inbred Strains

1988
Multiple effects of presumed glutathione depletors on rabbit proximal tubules.
    Kidney international, 1986, Volume: 29, Issue:4

    Topics: Animals; Buthionine Sulfoximine; Culture Techniques; Cyclohexanones; Female; Glutathione; Ketones; Kidney Concentrating Ability; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Maleates; Methionine Sulfoximine; Oxygen Consumption; Rabbits

1986
Effect of diethylmaleate and other glutathione depletors on protein synthesis.
    Biochemical pharmacology, 1986, Oct-01, Volume: 35, Issue:19

    Topics: Animals; Body Temperature; Brain; Buthionine Sulfoximine; Glutathione; Ketones; Liver; Male; Maleates; Methionine Sulfoximine; Mice; Protein Biosynthesis

1986
Inhibition of the low-Km mitochondrial aldehyde dehydrogenase by diethyl maleate and phorone in vivo and in vitro. Implications for formaldehyde metabolism.
    The Biochemical journal, 1986, Dec-15, Volume: 240, Issue:3

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Cytosol; Formaldehyde; In Vitro Techniques; Ketones; Liver; Male; Maleates; Mitochondria, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains

1986
Possible regulation mechanism of microsomal glutathione S-transferase activity in rat liver.
    Biochemical pharmacology, 1986, Feb-01, Volume: 35, Issue:3

    Topics: Animals; Disulfides; Glutathione; Glutathione Transferase; Ketones; Maleates; Microsomes, Liver; Oxidation-Reduction; Rats; Time Factors

1986
Effects of glutathione depletion on gluconeogenesis in isolated hepatocytes.
    Archives of biochemistry and biophysics, 1985, Aug-15, Volume: 241, Issue:1

    Topics: Adenosine Triphosphate; Animals; Buthionine Sulfoximine; Cell Survival; Gluconeogenesis; Glutathione; Glycerophosphates; Ketones; Liver; Malates; Maleates; Malondialdehyde; Methionine Sulfoximine; Rats; Urea

1985
Inhibition of mitochondrial aldehyde dehydrogenase and acetaldehyde oxidation by the glutathione-depleting agents diethylmaleate and phorone.
    Biochimica et biophysica acta, 1985, Nov-22, Volume: 843, Issue:1-2

    Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Ethanol; Glutathione; In Vitro Techniques; Ketones; Male; Maleates; Mitochondria, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains

1985
Radiosensitizers: a conference preview.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8

    Topics: Animals; Aziridines; Buthionine Sulfoximine; Carmustine; Combined Modality Therapy; Drug Synergism; Etanidazole; Humans; Ketones; Lomustine; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents

1984
Inhibition of the carrageenan-induced rat paw edema by glutathione-depleting agents.
    Agents and actions, 1984, Volume: 14, Issue:5-6

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Dichloroethylenes; Edema; Foot Diseases; Glutathione; Hindlimb; Ketones; Male; Maleates; Prostaglandin Antagonists; Rats; Rats, Inbred Strains

1984
Tissue-specific induction of intestinal glutathione S-transferases by alpha beta-unsaturated carbonyl compounds.
    Experientia, 1984, Nov-15, Volume: 40, Issue:11

    Topics: Animals; Enzyme Induction; Glutathione Transferase; Intestinal Mucosa; Ketones; Kidney; Kinetics; Liver; Male; Maleates; Rats; Rats, Inbred Strains

1984
Changes in hepatic glutathione concentration modify cadmium-induced hepatotoxicity.
    Toxicology and applied pharmacology, 1984, Mar-15, Volume: 72, Issue:3

    Topics: Alanine; Animals; Aspartic Acid; Cadmium Poisoning; Chemical and Drug Induced Liver Injury; Cysteine; Drug Synergism; Glutathione; Ketones; L-Iditol 2-Dehydrogenase; Liver; Liver Diseases; Male; Maleates; Rats; Rats, Inbred Strains; Transaminases; Triglycerides

1984
Chemically-induced glutathione depletion and lipid peroxidation.
    Chemico-biological interactions, 1982, Jul-01, Volume: 40, Issue:3

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Cyclohexanones; Cytochrome Reductases; Cytochrome-B(5) Reductase; Ethane; Fumarates; Glutathione; Ketones; Lipid Metabolism; Male; Maleates; Malondialdehyde; Mice; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxygenases; Proadifen

1982
Cardiac Na+/K+ ATPase activity and its relation to myocardial glutathione status: studies in the rat.
    Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:5

    Topics: Animals; Cell Membrane Permeability; Dose-Response Relationship, Drug; Glutathione; Heart Ventricles; Ketones; Male; Maleates; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase

1995
Liver and kidney necrosis in selenium-deficient rats depleted of glutathione.
    Laboratory investigation; a journal of technical methods and pathology, 1995, Volume: 72, Issue:6

    Topics: Animals; Buthionine Sulfoximine; Dinoprost; Glutathione; Ketones; Kidney; Lipid Peroxides; Liver; Male; Maleates; Methionine Sulfoximine; Necrosis; Osmolar Concentration; Proteins; Rats; Rats, Sprague-Dawley; Selenium; Selenoprotein P; Selenoproteins

1995
Modulation of gamma-glutamylcysteine synthetase large subunit mRNA expression by butylated hydroxyanisole.
    Toxicology and applied pharmacology, 1994, Volume: 126, Issue:1

    Topics: Animals; Base Sequence; Buthionine Sulfoximine; Butylated Hydroxyanisole; Diet; DNA, Complementary; Fasting; Gene Expression Regulation, Enzymologic; Glutamate-Cysteine Ligase; Glutathione; Ketones; Liver; Male; Maleates; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Molecular Sequence Data; RNA, Messenger

1994
Prostacyclin elevation following glutathione depletion in vivo. Possible threshold dependency in liver and lung.
    Biochemical pharmacology, 1993, Sep-14, Volume: 46, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprostone; Epoprostenol; Glutathione; Ketones; Kidney; Liver; Lung; Male; Maleates; Rats; Rats, Sprague-Dawley

1993
Changes in taurine as an indicator of hepatic dysfunction and biochemical perturbations. Studies in vivo and in vitro.
    Advances in experimental medicine and biology, 1996, Volume: 403

    Topics: Animals; Biomarkers; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cells, Cultured; Clenbuterol; Galactosamine; Glutathione; Ketones; Liver; Liver Diseases; Male; Maleates; Necrosis; Phenobarbital; Rats; Rats, Sprague-Dawley; Taurine; Thioacetamide

1996
2-Chloroacetophenone is an effective glutathione depletor in isolated rat hepatocytes.
    Archives of toxicology, 1996, Volume: 71, Issue:1-2

    Topics: Animals; Cells, Cultured; Glutathione; Ketones; Liver; Male; Maleates; omega-Chloroacetophenone; Rats; Rats, Wistar

1996
Cooperative induction of c-fos and heme oxygenase gene products under oxidative stress in human fibroblastic cells.
    Experimental cell research, 1997, Dec-15, Volume: 237, Issue:2

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Enzyme Induction; Fibroblasts; Flavonoids; Gene Expression Regulation, Enzymologic; Genes, Immediate-Early; Glutathione; Heme Oxygenase (Decyclizing); Humans; Ketones; Maleates; Mitogen-Activated Protein Kinases; Nerve Tissue Proteins; Oxidative Stress; Proto-Oncogene Proteins c-fos; RNA, Messenger

1997
Potential role of cerebral glutathione in the maintenance of blood-brain barrier integrity in rat.
    Neurochemical research, 1999, Volume: 24, Issue:12

    Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Blood-Brain Barrier; Brain; Curcuma; Glutathione; Ketones; Liver; Male; Maleates; Plant Extracts; Rats; Rats, Inbred Strains; Vitamin E

1999
Cerebral antioxidant status and free radical generation following glutathione depletion and subsequent recovery.
    Molecular and cellular biochemistry, 2000, Volume: 209, Issue:1-2

    Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Ceruloplasmin; Free Radicals; gamma-Glutamyltransferase; Glutathione; Hydrogen Peroxide; Hydroxides; In Vitro Techniques; Ketones; Male; Maleates; Rats; Rats, Inbred Strains; Reactive Oxygen Species; Superoxides; Thiobarbituric Acid Reactive Substances; Vitamin E

2000
Bioactivation and cytotoxicity of 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) in isolated rat hepatocytes.
    Pharmacology & toxicology, 2001, Volume: 88, Issue:4

    Topics: Animals; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Cyclic N-Oxides; Dose-Response Relationship, Drug; Fomepizole; Gas Chromatography-Mass Spectrometry; Glutathione; Halothane; Hepatocytes; In Vitro Techniques; Ketones; L-Lactate Dehydrogenase; Male; Maleates; Nitrogen Oxides; Pyrazoles; Pyridines; Rats; Rats, Wistar; Troleandomycin

2001
Reduced glutathione depletion causes necrosis and sensitization to tumor necrosis factor-alpha-induced apoptosis in cultured mouse hepatocytes.
    Hepatology (Baltimore, Md.), 2002, Volume: 36, Issue:1

    Topics: Acetaminophen; Animals; Antioxidants; Apoptosis; Butylated Hydroxytoluene; Caspase Inhibitors; Caspases; Cells, Cultured; Cytochrome c Group; DNA Fragmentation; Glutathione; Hepatocytes; Ketones; Maleates; Mice; Mice, Inbred C57BL; Necrosis; NF-kappa B; Oxidative Stress; Tumor Necrosis Factor-alpha; Vitamin E

2002