phormidolide has been researched along with 3-buten-2-one* in 1 studies
1 other study(ies) available for phormidolide and 3-buten-2-one
Article | Year |
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Synthesis of (E)-4-Bromo-3-methoxybut-3-en-2-one, the Key Fragment in the Polyhydroxylated Chain Common to Oscillariolide and Phormidolides A-C.
The terminal bromomethoxydiene (BMD) moiety of the polyhydroxylated chain present in phormidolides and oscillariolides has been synthesized for first time. Several strategies for the stereoselective synthesis of the 4-bromo-3-methoxybut-3-en-2-ones are described. Furthermore, a preliminary study to successfully introduce the BMD within the polyol chain and the fatty acid allowed us to corroborate the end structure of the polyol. Topics: Biological Products; Bromine; Butanones; Halogenation; Macrolides; Stereoisomerism | 2016 |