phorbols has been researched along with tretinoin in 93 studies
Studies (phorbols) | Trials (phorbols) | Recent Studies (post-2010) (phorbols) | Studies (tretinoin) | Trials (tretinoin) | Recent Studies (post-2010) (tretinoin) |
---|---|---|---|---|---|
2,217 | 0 | 72 | 23,654 | 1,083 | 6,085 |
Protein | Taxonomy | phorbols (IC50) | tretinoin (IC50) |
---|---|---|---|
Bile salt export pump | Homo sapiens (human) | 10 | |
Amyloid-beta precursor protein | Homo sapiens (human) | 0.18 | |
Adenosine receptor A3 | Homo sapiens (human) | 5.275 | |
Retinoic acid receptor alpha | Homo sapiens (human) | 2.2542 | |
60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 5.3 | |
Retinoic acid receptor beta | Homo sapiens (human) | 0.7537 | |
Retinoic acid receptor alpha | Mus musculus (house mouse) | 0.0057 | |
Retinoic acid receptor gamma | Homo sapiens (human) | 0.0064 | |
Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.275 | |
Retinoic acid receptor gamma | Mus musculus (house mouse) | 0.004 | |
Retinoic acid receptor beta | Mus musculus (house mouse) | 0.005 | |
Mitogen-activated protein kinase 1 | Homo sapiens (human) | 0.576 | |
Nuclear receptor ROR-alpha | Homo sapiens (human) | 0.1995 | |
Alpha-synuclein | Homo sapiens (human) | 3 | |
Cellular retinoic acid-binding protein 1 | Gallus gallus (chicken) | 0.5233 | |
5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.358 | |
Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.275 | |
Retinoic acid receptor RXR-gamma | Homo sapiens (human) | 0.35 | |
Nuclear receptor ROR-gamma | Homo sapiens (human) | 0.1995 | |
10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 5.3 | |
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | 0.82 | |
60 kDa chaperonin | Escherichia coli | 6.7 | |
10 kDa chaperonin | Escherichia coli | 6.7 | |
Nuclear receptor ROR-beta | Homo sapiens (human) | 0.1259 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 93 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Reich, E; Wilson, EL | 1 |
Easton, TG; Miskin, R; Reich, E | 1 |
Bozzone, JH; Fisher, PB; Weinstein, IB | 1 |
Dicker, P; Rozengurt, E | 2 |
Kensler, TW; Mueller, GC; Wertz, PW | 1 |
Boutwell, RK; Kensler, TW; Mueller, GC; Verma, AK; Wertz, PW | 1 |
Kensler, TW; Mueller, GC | 1 |
Boutwell, RK; Kensler, TW; Mueller, GC; Verma, AK | 1 |
Mueller, GC; Wertz, PW | 2 |
Levine, L; Ohuchi, K | 1 |
Boutwell, RK; Rice, HM; Shapas, BG; Verma, AK | 1 |
Boutwell, RK; Verma, AK | 2 |
Behnke, O; Olsson, L; Sørensen, HR | 1 |
Goldman, R | 1 |
Verma, AK | 1 |
Haddox, MK; Maddox, AM | 1 |
McCormick, DL; Moon, RC | 1 |
Enomoto, M; Fukuo, K; Kumahara, Y; Suzuki, F; Tajima, K; Takigawa, M | 1 |
Boutwell, RK; Cleaveland, JS; Ordman, AB; Simsiman, RC | 1 |
Matsui-Yuasa, I; Mimura, Y; Morisawa, S; Otani, S | 1 |
Center, MS; Marsh, W | 1 |
Chao, WR; Dawson, MI; Helmes, CT | 1 |
Grisham, JW; Smith, JD; Tsao, MS | 1 |
De Luca, LM; Jetten, AM | 2 |
Dauphinée, MJ; Talal, N | 1 |
Boutwell, RK; Simsiman, RC; Takigawa, M | 1 |
Wolf, G; Zerlauth, G | 3 |
Brodie, AE; Gescher, A; Reed, DJ | 1 |
Baumgarten, IM; Davidson, JS; Harley, EH | 1 |
Loprinzi, CL; Verma, AK | 1 |
Louache, F; Rochant, H; Testa, U; Thomopoulos, P; Titeux, M | 1 |
Asai, S; Ito, Y; Namikawa, I | 1 |
Ben, T; Lichti, U; Yuspa, SH | 1 |
Paulsen, JE | 1 |
Heidelberger, C; Mondal, S | 1 |
Adolf, GR; Swetly, P | 1 |
Goldfarb, RH; Herberman, RB | 1 |
Schweizer, J | 1 |
Nelson, KG; Slaga, TJ | 1 |
Grisham, JW; Nelson, KG; Tsao, MS | 1 |
Mastro, AM; Pepin, KG | 1 |
Ashendel, CL; Boutwell, RK; Verma, AK | 1 |
Gottesman, MM; Sobel, ME | 1 |
Kensler, TW; Trush, MA | 1 |
Amoruso, M; Goldstein, BD; Stone, DS; Troll, W; Witz, G | 1 |
Lin, JC; Pagano, JS; Smith, MC | 1 |
Jetten, AM | 2 |
Brinckerhoff, CE; Harris, ED | 1 |
Bauer, G; Yamamoto, N; zur Hausen, H | 1 |
Boutwell, RK; Conrad, EA; Verma, AK | 1 |
Egawa, K; Saito, M; Ueno, I | 1 |
Bowden, GT; Haussler, MR; Kelly, MA; Lockyer, JM; Magun, BE | 1 |
Lin, JC; Smith, MC | 1 |
Durham, JP; Fontana, JA; Ruppert, M | 1 |
Chida, K; Hashiba, H; Kuroki, T; Suda, T | 1 |
Borek, C; Geard, CR; Guernsey, DL; Miller, RC; Smith, JE | 1 |
Abrahamsson, L; Esscher, T; Mattsson, ME; Påhlman, S; Ruusala, AI | 1 |
Catovsky, D; Incarbone, E; Skinnider, L | 1 |
Kennedy, AR; Radner, BS | 1 |
Okabe, N; Saito, H; Suzuki, R; Yamada, K | 1 |
Asofsky, R; Hamano, T; Leiserson, WM | 1 |
Forbes, PD; Sambuco, CP | 1 |
Ito, T; Nagai, Y; Nakamura, H; Saito, H; Sanai, Y; Watanabe, N | 1 |
Lützelschwab, R; Wälder, L | 1 |
Bauer, G | 1 |
Slaga, TJ; Solanki, V | 1 |
Abruzzo, G; Ben, T; Colburn, NH; Jardini, E; Lichti, U; Ozanne, S; Wendel, E; Yuspa, SH | 1 |
Ben, T; Hennings, H; Lichti, U; Yuspa, SH | 1 |
Giesbrecht, K; Skinnider, LF | 1 |
Colburn, NH; Srinivas, L | 1 |
Bateman, J; Bear, J; Colburn, NH; De Luca, LM; Dion, LD | 1 |
Bolmer, SD; Wolf, G | 1 |
Blumberg, PM; Driedger, PE | 1 |
De Larco, JE; Paranjpe, MS; Todaro, GJ | 1 |
Kinzel, V; Krombholz-Nolinski, I; Richards, J; Stöhr, M | 1 |
Colburn, NH; Dion, LD; Wendel, EJ | 1 |
Astrup, EG; Paulsen, JE | 1 |
Boutwell, RK; Conrad, EA; Kishore, GS; Perchellet, JP | 1 |
Carchman, RA; Laskin, DL; Laskin, JD; Weinstein, IB | 1 |
Bash, JA; Baxter, CS; Fish, LA | 1 |
Colburn, NH; De Luca, LM; Dion, LD | 1 |
Olsnes, S; Sandvig, K | 1 |
Boutwell, RK; Mueller, GC; Slaga, TJ; Verma, AK; Wertz, PW | 1 |
Abb, J; Deinhardt, F | 1 |
Hennings, H; Lichti, U; Patterson, E; Yuspa, SH | 1 |
Borek, C; Geard, CR; Harisiadis, L; Mason, H; Miller, RC; Napholz, A; Ong, A; Osmak, RS; Perez, N; Rutledge-Freeman, M | 1 |
2 review(s) available for phorbols and tretinoin
Article | Year |
---|---|
Modification of epithelial cell differentiation in vivo by tumor-promoting diterpene esters.
Topics: Alkynes; Animals; Cell Differentiation; Cytoplasmic Granules; Epidermis; Hair; Hyperplasia; Keratins; Phorbol Esters; Phorbols; Protein Biosynthesis; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1982 |
Virus induction by tumor promoters.
Topics: Animals; Antigens, Viral; Canavanine; Carcinogens; Cell Line; Cell Transformation, Viral; Diterpenes; DNA, Viral; Enzyme Induction; Herpesviridae; Herpesvirus 4, Human; Humans; Ornithine Decarboxylase; Papillomaviridae; Phorbols; Polyomaviridae; Retroviridae; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin; Virus Activation | 1982 |
91 other study(ies) available for phorbols and tretinoin
Article | Year |
---|---|
Plasminogen activator in chick fibroblasts: induction of synthesis by retinoic acid; synergism with viral transformation and phorbol ester.
Topics: Animals; Cell Transformation, Viral; Cells, Cultured; Cyclic AMP; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Genes, Viral; Kinetics; Phorbols; Sarcoma, Experimental; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1978 |
Plasminogen activator in chick embryo muscle cells: induction of enzyme by RSV, PMA and retinoic acid.
Topics: Animals; Avian Sarcoma Viruses; Bucladesine; Cell Differentiation; Cell Fusion; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Cholera Toxin; Muscles; Phorbols; Plasminogen Activators; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1978 |
Tumor promoters and epidermal growth factor stimulate anchorage-independent growth of adenovirus-tranformed rat embryo cells.
Topics: Adenoviruses, Human; Animals; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Dexamethasone; Diterpenes; Embryo, Mammalian; Epidermal Growth Factor; Peptides; Phorbols; Protease Inhibitors; Rats; Tetradecanoylphorbol Acetate; Tretinoin | 1979 |
Retinoids enhance mitogenesis by tumour promotor and polypeptide growth factors.
Topics: Animals; Cell Division; Cell Line; Cricetinae; DNA; DNA Replication; Epidermal Growth Factor; Growth Substances; Insulin; Kinetics; Mice; Mice, Inbred BALB C; Peptides; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin; Vasopressins | 1979 |
Inhibition of phorbol ester-accelerated amino acid transport in bovine lymphocytes.
Topics: Aminoisobutyric Acids; Animals; Biological Transport, Active; Cattle; Cycloheximide; Dactinomycin; In Vitro Techniques; Lymphocytes; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1979 |
Synergistic stimulation of early events and DNA synthesis by phorbol esters, polypeptide growth factors, and retinoids in cultured fibroblasts.
Topics: Animals; Cell Line; Deoxyglucose; DNA; Fibroblasts; Growth Substances; Mice; Mitogens; Peptides; Phorbols; Potassium; Sodium; Tetradecanoylphorbol Acetate; Tretinoin; Uridine; Vasopressins | 1979 |
5,6-epoxyretinoic acid opposes the effects of 12-O-tetradecanoylphorbol-13-acetate in bovine lymphocytes.
Topics: Animals; Biotransformation; Cattle; Choline; Epoxy Compounds; Lymphocytes; Membrane Lipids; Phorbols; Phospholipids; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin | 1979 |
Retinoic acid inhibition of the comitogenic action of mezerein and phorbol esters in bovine lymphocytes.
Topics: Animals; Cattle; Diterpenes; DNA; Drug Synergism; In Vitro Techniques; Lectins; Lymphocyte Activation; Lymphocytes; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1978 |
Effects of retinoic acid and juvenile hormone on the induction of ornithine decarboxylase activity by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Carboxy-Lyases; Cattle; Drug Interactions; Enzyme Induction; In Vitro Techniques; Juvenile Hormones; Lectins; Lymphocyte Activation; Lymphocytes; Ornithine Decarboxylase; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1978 |
Rapid stimulation of phospholipid metabolism in bovine lymphocytes by tumor-promoting phorbol esters.
Topics: Cells, Cultured; Choline; Cycloheximide; Cytochalasin B; Dactinomycin; Drug Interactions; Lectins; Lymphocyte Activation; Lymphocytes; Phorbol Esters; Phorbols; Phospholipids; Tetradecanoylphorbol Acetate; Tretinoin | 1978 |
Retinoids as well as tumour promoters enhance deacylation of cellular lipids and prostaglandin production in MDCK cells.
Topics: Cell Line; Lipid Metabolism; Phorbols; Prostaglandins; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1978 |
Correlation of the inhibition by retinoids of tumor promoter-induced mouse epidermal ornithine decarboxylase activity and of skin tumor promotion.
Topics: Animals; Carboxy-Lyases; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Vitamin A | 1979 |
Vitamin A acid (retinoic acid), a potent inhibitor of 12-O-tetradecanoyl-phorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drug Administration Schedule; Enzyme Induction; Female; In Vitro Techniques; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1977 |
Modulatory effects of 5-azacytidine, phorbol ester, and retinoic acid on the malignant phenotype of human lung cancer cells.
Topics: Animals; Azacitidine; Carcinoma, Small Cell; Cell Line; Clone Cells; Humans; Lung Neoplasms; Mice; Mice, Nude; Mitosis; Neoplasm Transplantation; Phenotype; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Synergism and antagonism in the effects of 1 alpha,25-dihydroxyvitamin D3, retinoic acid, dexamethasone, and a tumor-promoting phorbol ester on the functional capability of P388D1 cells: phagocytosis and transglutaminase activity.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acyltransferases; Animals; Calcitriol; Cell Differentiation; Cell Line; Dexamethasone; Drug Synergism; Lymphoma; Mice; Phagocytosis; Phenotype; Phorbols; Prostaglandins; Tetradecanoylphorbol Acetate; Transglutaminases; Tretinoin | 1985 |
Inhibition of phorbol ester-caused synthesis of mouse epidermal ornithine decarboxylase by retinoic acid.
Topics: Acyltransferases; Animals; Antibodies, Monoclonal; Enzyme Induction; Female; Male; Mice; Ornithine Decarboxylase; Phorbols; Skin; Tetradecanoylphorbol Acetate; Transglutaminases; Tretinoin | 1985 |
Transglutaminase activity increases in HL60 cells induced to differentiate with retinoic acid and TPA but not with DMSO.
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Phorbols; Tetradecanoylphorbol Acetate; Time Factors; Transglutaminases; Tretinoin | 1985 |
Antipromotional activity of dietary N-(4-hydroxyphenyl)retinamide in two-stage skin tumorigenesis in CD-1 and SENCAR mice.
Topics: Animals; Carcinogens; Cocarcinogenesis; Diet; Drug Antagonism; Female; Fenretinide; Mice; Mice, Inbred Strains; Neoplasms, Multiple Primary; Phorbols; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Comparison of inhibition by a tumor promoter (12-O-tetradecanoylphorbol-13-acetate) of expression of the differentiated phenotype of chondrocytes in rabbit costal chondrocytes in culture with inhibition by retinoic acid.
Topics: Animals; Bucladesine; Cartilage; Cell Differentiation; Cells, Cultured; Cyclic AMP; Drug Interactions; Glycosaminoglycans; Ornithine Decarboxylase; Parathyroid Hormone; Phorbols; Proteoglycans; Rabbits; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
The role of prostaglandin E1 in ornithine decarboxylase induction by tumor promoters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alprostadil; Animals; Diterpenes; Enzyme Induction; Female; Indomethacin; Mice; Mice, Inbred Strains; Models, Biological; Neoplasms; Ornithine Decarboxylase; Phorbols; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Potentiation by retinoic acid of ornithine decarboxylase induction by phytohemagglutinin or phorbol 12-myristate 13-acetate in guinea pig lymphocytes.
Topics: Animals; Diterpenes; DNA; Drug Synergism; Eflornithine; Enzyme Induction; Guinea Pigs; In Vitro Techniques; Leucine; Lymphocytes; Ornithine; Ornithine Decarboxylase; Phorbols; Phytohemagglutinins; Polyamines; Retinyl Esters; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Vitamin A | 1986 |
Dimethylsulfoxide, retinoic acid and 12-O-tetradecanoylphorbol-13-acetate induce a selective decrease in the phosphorylation of P150, a surface membrane phosphoprotein of HL60 cells resistant to adriamycin.
Topics: Dimethyl Sulfoxide; Doxorubicin; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Myeloid, Acute; Membrane Proteins; Phorbols; Phosphoproteins; Phosphorylation; Protein Kinases; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Comparison of the inhibitory effects of retinoids on 12-O-tetradecanoylphorbol-13-acetate-induced epidermal ornithine decarboxylase activities in CD-1 and Sencar mice.
Topics: Animals; Dose-Response Relationship, Drug; Female; Isotretinoin; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Phorbols; Retinoids; Skin; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1985 |
The modulation of growth of normal rat liver epithelial cells in calcium-poor medium by epidermal growth factor, phenobarbital, phorbol ester, and retinoic acid.
Topics: Animals; Calcium; Cell Division; Cell Line; Cell Survival; Culture Media; Epidermal Growth Factor; Epithelial Cells; Epithelium; Liver; Phenobarbital; Phorbols; Rats; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1985 |
Retinoic acid and 12-O-tetradecanoylphorbol-13-acetate alter release of glycoproteins from mouse fibroblast BALB/C 3T6 cells.
Topics: Amino Acids; Animals; Cells, Cultured; Collagen; Fibroblasts; Glycoproteins; Mice; Mice, Inbred BALB C; Molecular Weight; Pepsin A; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Phorbol ester induction of Ia and a shared B-cell/T-cell phenotype in normal but not autoimmune (lpr) mice.
Topics: Animals; Antigens, Surface; B-Lymphocytes; Bone Marrow Cells; Cell Separation; Drug Interactions; Flow Cytometry; Genes, MHC Class II; Histocompatibility Antigens Class II; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Phenotype; Phorbols; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Tumor promoter-induced refractory state against ornithine decarboxylase induction by 12-O-tetradecanoylphorbol-13-acetate in mouse epidermis.
Topics: Acetone; Alkynes; Animals; Carcinogens; Cycloheximide; Diterpenes; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Induction; Epidermis; Female; Mice; Ornithine Decarboxylase; Papilloma; Phorbols; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Release of fibronectin is linked to tumor promotion: response of promotable and non-promotable clones of a mouse epidermal cell line.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Epidermis; Fibronectins; Mice; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Oxidative properties of 12-O-tetradecanoylphorbol-13-acetate-stimulated human blood monomorphonuclear leukocytes and their toxicity against a human lung carcinoma cell line.
Topics: Cell Line; Cytotoxicity, Immunologic; Free Radicals; Glutathione; Humans; Killer Cells, Natural; Leukocytes; Lung Neoplasms; Male; Middle Aged; Oxidation-Reduction; Phorbols; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Studies on the tumour promoter-induced release of fibronectin from human lung fibroblasts, and its counteraction by retinoic acid.
Topics: Cells, Cultured; Fibroblasts; Fibronectins; Humans; Lung; Phorbols; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1985 |
Effects of 12-O-tetradecanoylphorbol-13-acetate and retinoids on intercellular junctional communication measured with a citrulline incorporation assay.
Topics: Animals; Argininosuccinate Lyase; Argininosuccinate Synthase; Argininosuccinic Aciduria; Cell Communication; Cell Line; Cells, Cultured; Citrulline; Cricetinae; Cricetulus; Dimethyl Sulfoxide; Fibroblasts; Fluocinolone Acetonide; Intercellular Junctions; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Dose and schedule of oral retinoic acid and indomethacin needed to effectively inhibit phorbol ester-induced epidermal ornithine decarboxylase activity.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Indomethacin; Male; Mice; Mice, Inbred Strains; Ornithine Decarboxylase Inhibitors; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Effect of phorbol esters on iron uptake in human hematopoietic cell lines.
Topics: Biological Transport; Calcifediol; Calcitriol; Cell Line; Dimethyl Sulfoxide; Heme; Humans; Iron; Iron Radioisotopes; Kinetics; Leukemia, Myeloid, Acute; Phorbol Esters; Phorbols; Receptors, Cell Surface; Receptors, Transferrin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transferrin; Tretinoin | 1984 |
Ultrastructural studies on human lymphoblastoid cells treated with n-butyrate and 12-O-tetradecanoylphorbol-13-acetate.
Topics: Antigens, Viral; Butyrates; Butyric Acid; Cell Division; Cell Line; Herpesvirus 4, Human; Humans; Lymphocytes; Microscopy, Electron; Microscopy, Electron, Scanning; Microscopy, Phase-Contrast; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Regulation of epidermal transglutaminase activity and terminal differentiation by retinoids and phorbol esters.
Topics: Acyltransferases; Animals; Animals, Newborn; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Induction; Kinetics; Mice; Mice, Inbred BALB C; Phorbols; Protein Biosynthesis; Retinoids; Skin; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transglutaminases; Tretinoin | 1983 |
Effects of exogenous putrescine on the retinoic acid-induced reduction of 12-O-tetradecanoyl-phorbol-13-acetate-stimulated putrescine accumulation and rate of DNA synthesis in the hairless mouse epidermis.
Topics: Animals; DNA; Epidermis; Female; Mice; Mice, Hairless; Phorbols; Putrescine; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Inhibition of induced differentiation of C3H/10T 1/2 clone 8 mouse embryo cells by tumor promoters.
Topics: Animals; Antipain; Azacitidine; Cell Differentiation; Clone Cells; Embryo, Mammalian; Epidermal Growth Factor; Mice; Muscles; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Tumour-promoting phorbol esters inhibit DNA synthesis and enhance virus-induced interferon production in a human lymphoma cell line.
Topics: Burkitt Lymphoma; Butyrates; Cell Line; DNA; Humans; Interferons; Lymphoma; Melitten; Parainfluenza Virus 1, Human; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Natural killer cell reactivity: regulatory interactions and among phorbol ester, interferon, cholera toxin, and retinoic acid.
Topics: Animals; Cattle; Cholera Toxin; Humans; Interferons; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Mice, Nude; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Effects of inhibitors of tumor promotion on 12-O-tetradecanoylphorbol-13-acetate-induced keratin modification in mouse epidermis.
Topics: Animals; Carcinogens; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Epidermis; Female; Fluocinolone Acetonide; Hyperplasia; Keratins; Mice; Molecular Weight; Phorbols; Skin; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1982 |
Biochemical effects of 12-O-tetradecanoylphorbol-13-acetate, retinoic acid, phenobarbital, and 5-azacytidine on a normal rat liver epithelial cell line.
Topics: Animals; Azacitidine; Cell Division; Cells, Cultured; Fibronectins; Liver; Phenobarbital; Phorbols; Rats; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
The effects of retinoic acid and a tumor promoter, 12-O-tetradecanoylphorbol-13-acetate, on lymphocyte proliferation.
Topics: Animals; Cattle; Cell Division; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Phorbols; Phytohemagglutinins; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1982 |
Inhibition by prostaglandin synthesis inhibitors of the induction of epidermal ornithine decarboxylase activity, the accumulation of prostaglandins, and tumor promotion caused by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Carboxy-Lyases; Cyclooxygenase Inhibitors; Female; Indomethacin; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbols; Prostaglandins; Prostaglandins E, Synthetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Tumor promoters and Kirsten sarcoma virus increase synthesis of a secreted glycoprotein by regulating levels of translatable mRNA.
Topics: Animals; Cell Line; Cell Transformation, Viral; Epidermal Growth Factor; Glycoproteins; Kirsten murine sarcoma virus; Mice; Phorbols; Protein Biosynthesis; RNA, Messenger; Sarcoma Viruses, Murine; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Inhibiton of phorbol ester-stimulated chemiluminescence in human polymorphonuclear leukocytes by retinoic acid and 5,6-epoxyretinoic acid.
Topics: Cell Membrane; Epoxy Compounds; Humans; Luminescent Measurements; Neutrophils; Phagocytosis; Phorbol Esters; Phorbols; Structure-Activity Relationship; Superoxides; Tretinoin | 1981 |
Retinoid inhibition of superoxide anion radical production by human polymorphonuclear leukocytes stimulated with tumor promoters.
Topics: Alkaloids; Antipain; Cocarcinogenesis; Diterpenes; Humans; Indoles; Inflammation; Lyngbya Toxins; Neutrophils; Oxygen; Phorbol Esters; Phorbols; Superoxides; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1980 |
Induction of replication of Epstein-Barr virus DNA by 12-O-tetradecanoyl-phorbol-13-acetate. II. Inhibition by retinoic acid and 9-(2-hydroxyethoxymethyl) guanine.
Topics: Acyclovir; Cell Line; DNA Replication; DNA, Viral; Guanine; Herpesvirus 4, Human; Humans; Lymphocytes; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin; Virus Replication | 1981 |
Action of retinoids and phorbol esters on cell growth and the binding of epidermal growth factor.
Topics: Animals; Cell Division; Cell Line; Cricetinae; Epidermal Growth Factor; ErbB Receptors; Humans; Kidney; Kinetics; Lung; Mice; Peptides; Phorbol Esters; Phorbols; Receptors, Cell Surface; Skin; Structure-Activity Relationship; Tretinoin; Tunicamycin; Vitamin A | 1981 |
Modulation by retinoic acid and corticosteroids of collagenase production by rabbit synovial fibroblasts treated with phorbol myristate acetate or poly(ethylene glycol).
Topics: Animals; Cells, Cultured; Dexamethasone; Dinoprostone; Enzyme Induction; Fibroblasts; Microbial Collagenase; Phorbols; Polyethylene Glycols; Prednisolone; Prostaglandins E; Rabbits; Synovial Fluid; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
A possible role of protein alkylation in phorbol ester action.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Alkylation; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Choline-Phosphate Cytidylyltransferase; Enzyme Activation; Lymphocyte Activation; Lymphocytes; Nucleotidyltransferases; Oxygen; Phorbols; Phosphatidylcholines; Phytohemagglutinins; Proteins; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the complete carcinogenesis process and by the initiation-promotion regimen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Dose-Response Relationship, Drug; Enzyme Induction; Female; Flavonoids; Injections, Intraperitoneal; Methylcholanthrene; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Effect of retinoic acid and 12-O-tetradecanoyl phorbol-13-acetate on the binding of epidermal growth factor to its cellular receptors.
Topics: Animals; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Kinetics; Mice; Mice, Inbred C3H; Phorbols; Receptors, Cell Surface; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1982 |
Retinoic acid-induced changes in epidermal growth factor binding and in biological responses mediated by phorbol ester tumor promoter.
Topics: Animals; Carrier Proteins; Cell Division; Cell Line; DNA; Dose-Response Relationship, Drug; Drug Synergism; Epidermal Growth Factor; Mice; Ornithine Decarboxylase; Phorbols; Rats; Receptors, Retinoic Acid; Temperature; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Antagonistic action of retinoic acid against teleocidin and 12-O-tetradecanoyl-phorbol-13-acetate on activation of Epstein-Barr virus genomes.
Topics: Alkaloids; Burkitt Lymphoma; Carcinogens; Cell Line; Cell Survival; DNA Replication; Drug Antagonism; Genes, Viral; Herpesvirus 4, Human; Humans; Lyngbya Toxins; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin; Virus Replication | 1984 |
Glycosyltransferase activities and the differentiation of human promyelocytic (HL60) cells by retinoic acid and a phorbol ester.
Topics: Cell Differentiation; Cell Line; Fucosyltransferases; Galactosyltransferases; Hexosyltransferases; Humans; Kinetics; Leukemia, Myeloid, Acute; Neuraminidase; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Inhibition by 1 alpha, 25-dihydroxyvitamin D3 of induction of epidermal ornithine decarboxylase caused by 12-O-tetradecanoylphorbol-13-acetate and teleocidin B.
Topics: Alkaloids; Animals; Calcitriol; Drug Antagonism; Enzyme Induction; Female; Kinetics; Lyngbya Toxins; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Phorbols; Skin; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
In vitro modulation of oncogenesis and differentiation by retinoids and tumor promoters.
Topics: Adenosine Triphosphatases; Animals; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Cricetinae; Embryo, Mammalian; Mice; Phorbols; Retinol-Binding Proteins; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Tretinoin; X-Rays | 1982 |
Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbolester-induced differentiation.
Topics: Cell Differentiation; Cell Division; Cell Line; Humans; Neuroblastoma; Neurons; Norepinephrine; Phenotype; Phorbols; Phosphopyruvate Hydratase; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
The effect of tetradecanoyl-12, 13-phorbol acetate on 'hairy' cells.
Topics: Cells, Cultured; Cytochalasin D; Cytochalasins; Drug Interactions; Humans; Leukemia, Hairy Cell; Phagocytosis; Phorbols; Photography; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1984 |
Effects of agents known to antagonize the enhancement of in vitro transformation by 12-tetradecanoyl-phorbol-13-acetate (TPA) on the TPA suppression of metabolic cooperation.
Topics: Animals; Antipain; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Oligopeptides; Phorbols; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tretinoin; Trypsin Inhibitors | 1984 |
Action of retinoids on the anchorage-independent growth of normal rat kidney fibroblasts induced by 12-O-tetradecanoylphorbol-13-acetate or sarcoma growth factor.
Topics: Animals; Cell Adhesion; Cell Division; Cell Line; Fibroblasts; Kidney; Peptides; Phorbols; Rats; Retinol-Binding Proteins; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transforming Growth Factors; Tretinoin | 1983 |
[Induction of differentiation of human myelomonocytic cell lines by chemical inducers: analysis of surface antigens with monoclonal antibodies].
Topics: Antibodies, Monoclonal; Antigens, Surface; Cell Differentiation; Cell Line; Cells, Cultured; Granulocytes; Humans; Leukemia, Myeloid, Acute; Monocytes; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Functional studies on B-cell hybridomas with B-cell surface antigens. III. Differentiative response to phorbol esters.
Topics: Animals; Antigens, Surface; B-Lymphocytes; Cell Differentiation; Female; Histocompatibility Antigens Class II; Hybridomas; Immunoglobulin M; Mice; Mice, Inbred C57BL; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Thymidine; Tretinoin | 1984 |
Interactions of ultraviolet radiation, 12-O-tetradecanoyl-phorbol-13-acetate and retinoic acid in the skin of hairless mice.
Topics: Animals; Carcinogens; Cocarcinogenesis; Epidermis; Male; Mice; Mice, Hairless; Mitosis; Neoplasms, Radiation-Induced; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Ultraviolet Rays | 1983 |
Enhancement of clonal proliferation of mouse mast cells by a tumor-promoting phorbol ester.
Topics: Animals; Carcinogens; Cell Division; Cells, Cultured; Clone Cells; Dexamethasone; Female; Kinetics; Mast Cells; Mice; Mice, Inbred BALB C; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Effects of 12-O-tetradecanoylphorbol-13-acetate (TPA), retinoic acid and diazepam on intercellular communication in a monolayer of rat liver epithelial cells.
Topics: Animals; Cell Communication; Cell Line; Diazepam; Epithelium; Hypoxanthines; Intercellular Junctions; Liver; Liver Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Kinetics of fibronectin release from fibroblasts in response to 12-O-tetradecanoylphorbol-13-acetate and retinoic acid.
Topics: Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Fibroblasts; Fibronectins; Kinetics; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin; Tritium | 1984 |
Induction of Epstein-Barr virus early antigens by corticosteroids: inhibition by TPA and retinoic acid.
Topics: Adrenal Cortex Hormones; Animals; Antigens, Viral; Burkitt Lymphoma; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Humans; Kinetics; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin; Virus Activation | 1983 |
Specific binding of phorbol ester tumor promoters to intact primary epidermal cells from Sencar mice.
Topics: Animals; Animals, Newborn; Binding, Competitive; Caenorhabditis elegans Proteins; Carrier Proteins; Epidermis; Fluocinolone Acetonide; Kinetics; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Drug; Tretinoin | 1981 |
Retinoids inhibit promoter-dependent preneoplastic progression in mouse epidermal cell lines.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Mice; Phorbols; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Modulation of terminal differentiation and responses to tumor promoters by retinoids in mouse epidermal cell cultures.
Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Enzyme Induction; Mice; Ornithine Decarboxylase; Phorbols; Skin; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Inhibition of phorbol myristate acetate and phytohemagglutinin stimulation of human lymphocytes by 13-cis-retinoic acid and ethyl etrinoate.
Topics: Etretinate; Humans; Isotretinoin; Lymphocyte Activation; Lymphocytes; Phorbols; Phytohemagglutinins; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1981 |
Ganglioside changes induced by tumor promoters in promotable JB6 mouse epidermal cells: antagonism by an antipromoter.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Epidermis; Gangliosides; Mice; Phorbols; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1982 |
Inhibition by tumor-promoting phorbol esters of procollagen synthesis in promotable JB6 mouse epidermal cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Epidermis; Mice; Phorbol Esters; Phorbols; Procollagen; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Retinoids and phorbol esters alter release of fibronectin from enucleated cells.
Topics: Animals; Cell Membrane; Cell Nucleus; Cells, Cultured; Enzyme Induction; Fibronectins; Mice; Ornithine Decarboxylase; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Specific binding of phorbol ester tumor promoters.
Topics: Animals; Binding, Competitive; Cells, Cultured; Chick Embryo; Dexamethasone; Epidermal Growth Factor; Kinetics; Phorbol Esters; Phorbols; Prostaglandins E; Receptors, Drug; Structure-Activity Relationship; Tretinoin | 1980 |
Retinoids block ornithine decarboxylase induction in cells treated with the tumor promotor TPA or the peptide growth hormones, EGF and SGF.
Topics: Animals; Carboxy-Lyases; Cell Line; Enzyme Induction; Epidermal Growth Factor; Growth Inhibitors; Kidney; Ornithine Decarboxylase; Phorbols; Rats; Sarcoma, Experimental; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1980 |
Studies on antagonistic actions of TPA and retinoic acid.
Topics: Animals; Cell Adhesion; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Contact Inhibition; Epidermal Growth Factor; Mice; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Effects of retinoic acid and tumor promoter 12-o-tetradecanoylphorbol-13-acetate (TPA) on the cell cycle of HeLa cells.
Topics: Cell Cycle; Cell Division; Cell Transformation, Neoplastic; DNA; Drug Interactions; Flow Cytometry; HeLa Cells; Humans; Mitosis; Phorbols; Tetradecanoylphorbol Acetate; Thymidine; Tretinoin | 1982 |
The role of mitogenic stimulation and specific glycoprotein changes in the mechanism of late-stage promotion in JB-6 epidermal cell lines.
Topics: Animals; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Epidermis; Mice; Mitogens; Phorbols; Procollagen; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Effect of retinoic acid pretreatment on 12-O-tetradecanoylphorbol-13-acetate-induced cell population kinetics and polyamine biosynthesis in hairless mouse epidermis.
Topics: Adenosylmethionine Decarboxylase; Animals; DNA; Female; Kinetics; Male; Metaphase; Mice; Mice, Hairless; Ornithine Decarboxylase; Phorbols; Polyamines; Skin; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1982 |
Effects of cell surface receptor-altering agents on the binding and biological activity of 12-O-tetradecanoylphorbol-13-acetate in isolated epidermal cells.
Topics: alpha-L-Fucosidase; Animals; Atropine; Binding Sites; Binding, Competitive; Carboxy-Lyases; Cell Membrane; Cholera Toxin; G(M1) Ganglioside; Galactose Oxidase; Kinetics; Mice; Neuraminidase; Ornithine Decarboxylase; Phentolamine; Phorbols; Phospholipases; Propranolol; Skin; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Induction of chemotaxis in mouse peritoneal macrophages by phorbol ester tumor promoters.
Topics: Animals; Ascitic Fluid; Chemotaxis, Leukocyte; Cocarcinogenesis; In Vitro Techniques; Macrophages; Mice; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tretinoin | 1981 |
Murine lymphocyte comitogenesis by phorbol esters, and its inhibition by retinoic acid and inhibitors of polyamine biosynthesis.
Topics: Animals; Concanavalin A; Female; Lymphocytes; Mice; Mitogens; Phorbol Esters; Phorbols; Phytohemagglutinins; Polyamines; Spleen; Tretinoin | 1981 |
Phorbol ester-induced anchorage independence and its antagonism by retinoic acid correlates with altered expression of specific glycoproteins.
Topics: Animals; Carcinogens; Cell Adhesion; Cells, Cultured; Gene Expression Regulation; Glycoproteins; Mice; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Effects of retinoids and phorbol esters on the sensitivity of different cell lines to the polypeptide toxins modeccin, abrin, ricin and diphtheria toxin.
Topics: Abrin; Animals; Cell Line; Cell Survival; Chlorocebus aethiops; Diphtheria Toxin; HeLa Cells; Humans; L Cells; Lectins; Phorbols; Plant Lectins; Protein Biosynthesis; Rats; Ribosome Inactivating Proteins, Type 2; Ricin; Tetradecanoylphorbol Acetate; Toxins, Biological; Tretinoin | 1981 |
Inhibition of skin tumor promotion by retinoic acid and its metabolite 5,6-epoxyretinoic acid.
Topics: Animals; Female; Juvenile Hormones; Mice; Ornithine Decarboxylase Inhibitors; Papilloma; Phorbol Esters; Phorbols; Skin Neoplasms; Time Factors; Tretinoin | 1980 |
Retinoids inhibit the mitogenic activity of tumour-promoting phorbol esters on human lymphocytes.
Topics: Carrier Proteins; Cell Division; Humans; Lymphocyte Activation; Lymphocytes; Mitogens; Neoplasms; Phorbol Esters; Phorbols; Tretinoin | 1980 |
An organ culture of adult mouse skin: an in vitro model for studying the molecular mechanism of skin tumor promotion.
Topics: Animals; Carboxy-Lyases; DNA; Enzyme Induction; Female; Indomethacin; Mice; Models, Biological; Neoplasms, Experimental; Organ Culture Techniques; Ornithine Decarboxylase; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Differential retinoic acid inhibition of ornithine decarboxylase induction by 12-O-tetradecanoylphorbol-13-acetate and by germicidal ultraviolet light.
Topics: Animals; Carboxy-Lyases; Cells, Cultured; DNA Replication; Enzyme Induction; Epidermal Cells; Mice; Ornithine Decarboxylase; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin; Ultraviolet Rays | 1981 |
Modification of sister chromatid exchanges and radiation-induced transformation in rodent cells by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate and two retinoids.
Topics: Animals; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Cricetinae; Crossing Over, Genetic; Mice; Phorbols; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |