Page last updated: 2024-09-04

phorbols and phorbol

phorbols has been researched along with phorbol in 127 studies

Compound Research Comparison

Studies
(phorbols)
Trials
(phorbols)
Recent Studies (post-2010)
(phorbols)
Studies
(phorbol)
Trials
(phorbol)
Recent Studies (post-2010) (phorbol)
2,217072135022

Research

Studies (127)

TimeframeStudies, this research(%)All Research%
pre-199047 (37.01)18.7374
1990's36 (28.35)18.2507
2000's25 (19.69)29.6817
2010's14 (11.02)24.3611
2020's5 (3.94)2.80

Authors

AuthorsStudies
Paradiso, AM1
Bosca, L; Cascales, M; Martin-Sanz, P1
Andrews, PE; Montgomery, BT; Tindall, DJ; Young, CY1
Byrne, JH; Critz, SD1
Raufman, JP1
Calixto, JB; Guimarães, CL; Rae, GA1
Gross, JL; Horuk, R1
Sacktor, TC; Schwartz, JH1
Alterman, RL; Kornblith, PL; Maleci, A; Moskal, JR; Sundstrom, D1
Brown, BL; Dobson, PR; Quilliam, LA1
Field, JB; Nielsen, TB; Rani, CS; Tanabe, A1
Burton, DW; Deftos, LJ; Murray, SS1
Choi, EJ; Toscano, WA1
Hogans, BB; Spivak, JL; Stuart, RK1
Brown, BL; Dobson, PR; Evans, DB; Russell, RG1
Hoshi, T; Shimada, T1
Hirata, Y1
Chuang, DM; Dillon-Carter, O1
Morgan, EH; Sorokin, LM; Yeoh, GC1
Insel, PA; Slivka, SR1
Entwistle, A; Farzaneh, F; Zalin, RJ1
Bauer, KD; Dunn, MM; Kamp, DW; Rubin, DB1
de Graan, PN; Eichberg, J; Gispen, WH; Schrama, LH1
Carpenter, CL; Greenberg, DA; Messing, RO1
Drummond, AH; MacIntyre, DE; McNicol, A1
Brown, JH; Orellana, SA; Solski, PA1
Civan, MM; Mauro, T; O'Brien, TG; Rubenstein, D1
Carr, BR; Mason, JI; Rainey, WE1
el-Fakahany, EE; Lai, WS2
Blenis, J; Erikson, RL1
Boyd, AW; Forsgren, A; Nadler, LM; Schlossman, SF; Tedder, TF1
Amir, S1
Kuramoto, A; Matsui, I; Morisawa, S; Otani, S1
Craven, PA; DeRubertis, FR; Patterson, MC1
Bayard, F; Darbon, JM; Valette, A1
Murphy, RL; Smith, ME1
Chobanian, MC; Hammerman, MR1
Jung, CY; Martz, A; Mookerjee, BK1
Kojo, S; Tsukamoto, I1
Finlay, TH; Kadner, SS; Katz, J; Levitz, M1
Cohen, A; Mellors, A; Stalmach, ME1
Lefkowitz, RJ; Nambi, P; Sibley, DR1
de Haas, CG; Vaartjes, WJ1
Cooke, E; Hallett, MB1
Baird, AW; Evans, FJ; Pearce, JB; Williamson, EM1
Adelstein, RS; Hidaka, H; Nishikawa, M; Sellers, JR1
Nomura, S; Oishi, M; Shobu, N1
Peterfreund, RA; Vale, WW1
Bishop, R; Martinez, R; Nakamura, KD; Weber, MJ1
Kuwata, T; Morinaga, N1
Janowsky, A; Labarca, R; Patel, J; Paul, SM1
Kuroda, Y; Mikami, H1
Park, CH1
Bash, JA; Baxter, CS; Ferguson, TA; Fish, LA; Michael, JG1
Bols, NC; Mosser, DD1
Malbon, CC; Strassheim, D1
Chen, H; Jassar, BS; Kurenny, DE; Smith, PA1
Abello, J; Bosshard, A; Chayvialle, JA; Saifia, S1
Juengel, JL; McGuire, WJ; Niswender, GD1
Araki, M; Inaba, H; Numai, T1
Bandres, JC; Ratner, L1
Black, SC; Chi, L; Fagbemi, SO; Friedrichs, GS; Lucchesi, BR1
Ichikawa, K; Ito, M; Itoh, H; Konishi, T; Nakano, T; Okubo, S; Shimomura, A1
Finnegan, SG; Koenig, E; Lemmon, VP1
Ashby, CR; Edwards, E; Wang, RY1
Frindt, G; Palmer, LG; Windhager, EE1
Aten, RF; Behrman, HR; Preston, SL; Rinaudo, P; Zreik, TG1
Barr, SC; Gilmour, RF; Han, W; Pacioretty, LM1
Hirsh, JK; Redman, RS; Searl, TJ; Silinsky, EM1
Hirono, M; Suzuki, N; Takagi, H; Yoshioka, T1
Colbert, CM; Johnston, D1
Brown, S; Garcia, DE; Hille, B; Mackie, K1
Abdullah, LH; Davis, CW; Scott, CE1
Agosti, SJ; Gallatin, WM; Hakala, S; Hoffman, P; Rabb, H; Ramirez, G1
Camerino, C; Conte Camerino, D; De Luca, A; Liantonio, A; Pierno, S1
Bhagavan, S; Etcheberrigaray, R; Ibarreta, D; Kozikowski, AP; Ma, D1
Kim, YH; Koh, JY; Noh, KM1
Conn, PJ; Macek, TA; Schaffhauser, H1
Gomes, R; Sampaio-Maia, B; Soares-da-Silva, P1
Hamad, AM; Knox, AJ1
Amara, SG; Daniels, GM1
Alam, T; Hamawy, MM; Knechtle, SJ; Manthei, ER; Tsuchida, M1
Hubbard, PC; Lummis, SC; Thompson, AJ1
Nass, JU; Nuskovski, M; Pleyer, U; Strauss, O; Thieme, H; Wiederholt, M1
Khan, N; McDonald, RL; Peers, C; Roberts, DJ; Vaughan, PF; Webster, NJ1
Cha, JK; Lee, K1
Arenson, MS; Evans, SC1
Barak, D; Rein, R; Shibata, M1
Dunlop, J; Hediger, MA; Peng, JB; Trotti, D1
Asano, Y; Ishibashi, S; Miyata, Y; Muto, S; Okada, K1
Cubillos, S; Guerra, A; Lima, L1
Benham, CD; Cairns, W; Davis, JB; Droogmans, G; Flockerzi, V; Hayes, P; Jerman, JC; Nilius, B; Prenen, J; Smart, D; Smith, GD; Vriens, J; Watanabe, H; Wissenbach, U1
Abdel-Hafez, AA; Hattori, M; Nakamura, N1
Green, M; Mehta, A; Muimo, R; Mwimbi, XK; Sijumbila, G; Treharne, KJ1
Hall, D; Hursthouse, MB; Malik, A; Marson, CM; Pink, JH; Smith, C1
Berghman, LR; Byrd, JA; Caldwell, DJ; Caldwell, DY; Hargis, BM; McElroy, AP; Moore, RW1
Jardemark, KE; Liang, X; Ninan, I; Wang, RY1
Franklin, RA; Howe, CJ; LaHair, MM; McCubrey, JA; Robinson, PJ; Rodriguez-Mora, O1
Blakely, RD; Jayanthi, LD; Ramamoorthy, S; Samuvel, DJ1
Kakegawa, W; Kondo, T; Yuzaki, M1
Harada, N; Kubo, N; Liu, B; Mizuno, A; Shen, J; Suzuki, M; Yamashita, T1
Das, UN; Rao, KP1
Abramoff, T; Adler-Graschinsky, E; Neuman, I; Orliac, ML; Peroni, RN; Podesta, EJ1
Brueggemeier, RW; Díaz-Cruz, ES; Landini, S; Su, B1
Kee, JM; Warrington, JM; Wender, PA1
Afrasiabi, E; Ahlgren, J; Bergelin, N; Törnquist, K1
DeSimone, JA; Lyall, V; Mahavadi, S; Melone, P; Mummalaneni, S; Murthy, KS; Phan, TH1
Elsässer, A; Hamm, CW; Kostin, S; Möllmann, H; Nef, H; Rolf, A; Schaper, W; Schilp, A; Schmitz-Rixen, T; Szardien, S; Troidl, C; Troidl, K; Voss, S1
Fulton, DJ; Pandey, D1
Chen, L; Chen, RM; Han, J; Hong, L; Hu, WY; Liao, R; Sun, P; Xu, Z; Yoshizuka, N; Yu, G1
Li, JY; Qi, HY; Shi, YP; Wang, R1
Chang, HT; Chen, IL; Chou, CT; Huang, JK; Jan, CR; Kuo, DH; Liang, WZ; Shieh, P1
Bader, A; Braca, A; Giner, RM; Martini, F; Prieto, JM; Ríos, JL; Schinella, GR1
Kerubo, LO; Langat, MK; Midiwo, JO; Ndunda, B; Wanjohi, JM1
Aki, N; Funaki, M; Hata, A; Nishimura, M; Oyadomari, S; Shikama, Y1
Blumberg, PM; Keck, GE; Kedei, N; Kraft, MB; Lewin, NE; Peach, ML; Poudel, YB1
Baran, PS; Chu, H; Felding, J; Kawamura, S1
Hanada, Y; Horii, A; Imai, T; Inohara, H; Ishida, Y; Kamakura, T; Kitahara, T; Kondo, M; Koyama, Y; Nakamura, Y; Ozono, Y; Shimada, S; Takimoto, Y; Yamada, T1
Daigo, Y; Sumimoto, H; Takano, A; Teramoto, K1
Barnard, RJ; Blair, W; Hazuda, D; Howell, BJ; Maxwell, JW; Nefedov, A; Newhard, W; Sanchez, RI; Steve, J; Tellers, D; Vemula, SV; Wan, BL; Webber, AL1
Alabdul Magid, A; Benmerache, A; Hubert, J; Kabouche, A; Kabouche, Z; Labed, A; Morjani, H; Voutquenne-Nazabadioko, L1
Behm, DJ; Brnardic, EJ; Lawhorn, BG1
Ishibashi, M; Ishizu, A; Kato, K; Masuda, S; Nakazawa, D; Nishibata, Y; Sugimoto, A; Tanaka, S; Tomaru, U; Tsujino, I1
Kim, JE; Lee, SH; Park, NR1
Chen, HP; Fan, JP; Gao, Y; He, BT; Peng, HL; Xie, CF1
Barnes, AB; Judge, PT; Overall, SA1

Reviews

1 review(s) available for phorbols and phorbol

ArticleYear
Recent advances in TRPV4 agonists and antagonists.
    Bioorganic & medicinal chemistry letters, 2020, 04-15, Volume: 30, Issue:8

    Topics: Biological Products; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Phorbols; TRPV Cation Channels

2020

Other Studies

126 other study(ies) available for phorbols and phorbol

ArticleYear
Identification of Na(+)-H+ exchange in human normal and cystic fibrotic ciliated airway epithelium.
    The American journal of physiology, 1992, Volume: 262, Issue:6 Pt 1

    Topics: Adolescent; Adult; Amiloride; Carrier Proteins; Cells, Cultured; Cilia; Cystic Fibrosis; Epithelium; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Nasal Mucosa; Nasal Polyps; Phorbols; Potassium; Reference Values; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate

1992
Phorbol esters, bombesin and insulin elicit differential responses on the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase system in primary cultures of foetal and adult rat hepatocytes.
    European journal of biochemistry, 1992, Jul-01, Volume: 207, Issue:1

    Topics: Animals; Bombesin; Cells, Cultured; Cycloheximide; Female; Fetus; Insulin; Kinetics; Liver; Male; Phorbols; Phosphofructokinase-2; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotransferases; Pregnancy; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1992
Tumor-promoting phorbol ester down-regulates the androgen induction of prostate-specific antigen in a human prostatic adenocarcinoma cell line.
    Cancer research, 1992, Mar-15, Volume: 52, Issue:6

    Topics: Alkaloids; Antigens, Neoplasm; Biomarkers, Tumor; Calcimycin; Colforsin; Dose-Response Relationship, Drug; Down-Regulation; Humans; Male; Nandrolone; Phorbols; Prostate-Specific Antigen; Prostatic Neoplasms; RNA, Messenger; Staurosporine; Testosterone Congeners; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Modulation of IK,Ca by phorbol ester-mediated activation of PKC in pleural sensory neurons of Aplysia.
    Journal of neurophysiology, 1992, Volume: 68, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aplysia; Calcium; Dose-Response Relationship, Drug; Enzyme Activation; Ganglia; In Vitro Techniques; Isoquinolines; Kinetics; Membrane Potentials; Neurons, Afferent; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Piperazines; Potassium Channels; Protein Kinase C; Protein Kinase Inhibitors; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetraethylammonium Compounds

1992
Actions of phorbol esters on levels of cAMP in cholera toxin-treated chief cells from guinea pig stomach.
    Biochimica et biophysica acta, 1992, Apr-30, Volume: 1135, Issue:1

    Topics: Animals; Calcimycin; Calmodulin; Carbachol; Cholera Toxin; Gastric Mucosa; Guinea Pigs; Imidazoles; In Vitro Techniques; Kinetics; Male; Phorbol 12,13-Dibutyrate; Phorbols; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate

1992
Potent constrictor actions of endothelin-1, endothelin-2, and endothelin-3 in rat isolated portal vein.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:2 Suppl

    Topics: Alkaloids; Animals; Benzopyrans; Calcium; Cromakalim; Endothelins; Glyburide; Indomethacin; Male; Mesenteric Veins; Nicardipine; Phorbols; Portal Vein; Protein Kinase C; Pyrroles; Rats; Rats, Inbred Strains; Staurosporine; Vasoconstriction; Vasodilator Agents

1992
Protein kinase C-linked inactivation of the interleukin-1 receptor in a human transformed B-cell line.
    Biochimica et biophysica acta, 1990, Apr-09, Volume: 1052, Issue:1

    Topics: B-Lymphocytes; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Cell Membrane; Enzyme Activation; Humans; Interleukin-1; Kinetics; Lymphoma; Phorbol 12,13-Dibutyrate; Phorbols; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Receptors, Interleukin-1; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Sensitizing stimuli cause translocation of protein kinase C in Aplysia sensory neurons.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:5

    Topics: Animals; Aplysia; Caenorhabditis elegans Proteins; Carrier Proteins; Cyclic AMP; Ganglia; Histones; In Vitro Techniques; Magnesium; Neurons, Afferent; Phorbol 12,13-Dibutyrate; Phorbols; Phosphorylation; Protein Kinase C; Receptors, Drug; Serotonin; Subcellular Fractions; Thionucleotides

1990
Effect of phorbol esters on the susceptibility of a glioma cell line to lymphokine-activated killer cell activity.
    Journal of neurosurgery, 1990, Volume: 73, Issue:1

    Topics: Cell Division; Glioma; Humans; Killer Cells, Lymphokine-Activated; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured

1990
Modulation of cyclic AMP accumulation in GH3 cells by a phorbol ester and thyroliberin.
    Biochemical and biophysical research communications, 1985, Jun-28, Volume: 129, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Bacterial Toxins; Cell Line; Cholera Toxin; Cyclic AMP; GTP-Binding Proteins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pituitary Gland; Pituitary Neoplasms; Rats; Thyrotropin-Releasing Hormone; Time Factors; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella

1985
Thyroid cell responses to thyrotropin and 12-O-tetradecanoyl-phorbol-13-acetate: translocation of protein kinase C and phosphorylation of thyroid cell polypeptide substrates.
    Archives of biochemistry and biophysics, 1985, Nov-15, Volume: 243, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cattle; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Molecular Weight; Peptides; Phorbols; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Time Factors

1985
The coregulation of secretion and cytoplasmic ribonucleic acid of chromogranin-A and calcitonin by phorbol ester in cells that produce both substances.
    Endocrinology, 1988, Volume: 122, Issue:2

    Topics: Calcitonin; Cell Line; Chromogranin A; Chromogranins; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Nerve Tissue Proteins; Nucleic Acid Hybridization; Phorbol Esters; Phorbols; RNA; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Tumor Cells, Cultured

1988
Modulation of adenylate cyclase in human keratinocytes by protein kinase C.
    The Journal of biological chemistry, 1988, Nov-15, Volume: 263, Issue:32

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Line; Epidermis; Humans; Isoproterenol; Keratins; Pertussis Toxin; Phorbol Esters; Phorbols; Propranolol; Protein Kinase C; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1988
Tumor-promoting phorbol esters support the in vitro proliferation of murine pluripotent hematopoietic stem cells.
    The Journal of clinical investigation, 1989, Volume: 83, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Colony-Forming Units Assay; Colony-Stimulating Factors; Dose-Response Relationship, Drug; Erythropoietin; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Hematopoietic Stem Cells; Indomethacin; Interleukin-3; Isoquinolines; Mice; Phorbols; Piperazines; Tetradecanoylphorbol Acetate; Time Factors

1989
Agents affecting adenylate cyclase activity modulate the stimulatory action of 1,25-dihydroxyvitamin D3 on the production of osteocalcin by human bone cells.
    Biochemical and biophysical research communications, 1989, Nov-15, Volume: 164, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alkaline Phosphatase; Bone and Bones; Bucladesine; Calcitriol; Cells, Cultured; Colforsin; Humans; Interleukin-1; Kinetics; Osteoblasts; Osteocalcin; Phorbols; Recombinant Proteins; Theophylline

1989
Na+-dependent elevation of the acidic cell surface pH (microclimate pH) of rat jejunal villus cells induced by cyclic nucleotides and phorbol ester: possible mediators of the regulation of the Na+/H+ antiporter.
    Biochimica et biophysica acta, 1988, Jan-22, Volume: 937, Issue:2

    Topics: Amiloride; Animals; Bucladesine; Calcimycin; Carrier Proteins; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprostone; Hydrogen-Ion Concentration; Jejunum; Male; Microvilli; Phorbol Esters; Phorbols; Prostaglandins E; Rats; Rats, Inbred Strains; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Theophylline

1988
Heterologous down-regulation of vascular atrial natriuretic peptide receptors by phorbol esters.
    Biochemical and biophysical research communications, 1988, May-16, Volume: 152, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Temperature; Tetradecanoylphorbol Acetate; Time Factors

1988
Characterization of bradykinin-induced phosphoinositide turnover in neurohybrid NCB-20 cells.
    Journal of neurochemistry, 1988, Volume: 51, Issue:2

    Topics: Animals; Bradykinin; Cell Line; Diphenhydramine; GTP-Binding Proteins; Kinetics; Lithium; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylinositols; Triprolidine; Type C Phospholipases

1988
Differences in transferrin receptor function between normal developing and transformed myogenic cells as revealed by differential effects of phorbol ester on receptor distribution and rates of iron uptake.
    The Journal of biological chemistry, 1988, Oct-05, Volume: 263, Issue:28

    Topics: Animals; Avian Sarcoma Viruses; Biological Transport; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Conalbumin; DNA Replication; Iron; Kinetics; Muscles; Phorbols; Receptors, Transferrin; Tetradecanoylphorbol Acetate

1988
Phorbol ester and neomycin dissociate bradykinin receptor-mediated arachidonic acid release and polyphosphoinositide hydrolysis in Madin-Darby canine kidney cells. Evidence that bradykinin mediates noninterdependent activation of phospholipases A2 and C.
    The Journal of biological chemistry, 1988, Oct-15, Volume: 263, Issue:29

    Topics: Animals; Arachidonic Acids; Bradykinin; Calcimycin; Cell Line; Dogs; Enzyme Activation; Hydrolysis; Kidney; Kinetics; Neomycin; Phorbols; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipases; Phospholipases A; Phospholipases A2; Receptors, Bradykinin; Receptors, Neurotransmitter; Tetradecanoylphorbol Acetate; Type C Phospholipases

1988
Protein kinase C mediates the hormonally regulated plasma membrane fusion of avian embryonic skeletal muscle.
    Experimental cell research, 1989, Volume: 181, Issue:1

    Topics: Alprostadil; Animals; Cell Fusion; Cells, Cultured; Chick Embryo; Diglycerides; DNA; Enzyme Activation; Indomethacin; Muscles; Myosins; Phorbols; Protein Kinase C; Tetradecanoylphorbol Acetate

1989
Tumor-promoting phorbol esters inhibit monocyte adherence to endothelial cells.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:1

    Topics: Animals; Aorta; Carcinogens; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Male; Monocytes; Phorbol 12,13-Dibutyrate; Phorbols; Tetradecanoylphorbol Acetate

1989
Dioctanoylglycerol and phorbol diesters enhance phosphorylation of phosphoprotein B-50 in native synaptic plasma membranes.
    Biochemical and biophysical research communications, 1986, May-14, Volume: 136, Issue:3

    Topics: Animals; Calcium; Diglycerides; Dose-Response Relationship, Drug; GAP-43 Protein; Glycerides; Histones; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Synaptic Membranes

1986
Inhibition of calcium flux and calcium channel antagonist binding in the PC12 neural cell line by phorbol esters and protein kinase C.
    Biochemical and biophysical research communications, 1986, May-14, Volume: 136, Issue:3

    Topics: Animals; Calcium; Calcium Channel Blockers; Cell Line; Diglycerides; Enzyme Activation; Isradipine; Mice; Neural Crest; Oxadiazoles; Phorbol Esters; Phorbols; Potassium; Protein Kinase C; Tetradecanoylphorbol Acetate

1986
Tumour-promoting phorbol esters inhibit agonist-induced phosphatidate formation and Ca2+ flux in human platelets.
    FEBS letters, 1985, Jan-28, Volume: 180, Issue:2

    Topics: Blood Platelets; Calcium; Carcinogens; Enzyme Activation; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylinositols; Platelet Activating Factor; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Thrombin; Vasopressins

1985
Phorbol ester inhibits phosphoinositide hydrolysis and calcium mobilization in cultured astrocytoma cells.
    The Journal of biological chemistry, 1985, May-10, Volume: 260, Issue:9

    Topics: Astrocytoma; Calcium; Carbachol; Cells, Cultured; Humans; Hydrolysis; Phorbol Esters; Phorbols; Phosphatidylinositols; Receptors, Muscarinic; Tetradecanoylphorbol Acetate

1985
Effects of tumor promoters on sodium ion transport across frog skin.
    The American journal of physiology, 1985, Volume: 248, Issue:5 Pt 1

    Topics: Amiloride; Animals; Biological Transport, Active; Carcinogens; Cyclic AMP; Indomethacin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Rana pipiens; Skin; Sodium; Tetradecanoylphorbol Acetate

1985
The action of phorbol ester on steroidogenesis in cultured human fetal adrenal cells.
    Endocrine research, 1986, Volume: 12, Issue:4

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Bucladesine; Cells, Cultured; Cyclic AMP; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diglycerides; Humans; Hydrocortisone; Phorbol Esters; Phorbols; Protein Kinase C; Steroid Hydroxylases; Tetradecanoylphorbol Acetate

1986
Phorbol ester-induced inhibition of cyclic GMP formation mediated by muscarinic receptors in murine neuroblastoma cells.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Carbachol; Cell Line; Cyclic GMP; Dose-Response Relationship, Drug; Histamine; Isoquinolines; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Piperazines; Receptors, Muscarinic; Tetradecanoylphorbol Acetate

1987
Stimulation of ribosomal protein S6 kinase activity by pp60v-src or by serum: dissociation from phorbol ester-stimulated activity.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:6

    Topics: Animals; Blood Physiological Phenomena; Chick Embryo; Cycloheximide; Enzyme Activation; Fibroblasts; Glucose; Oncogene Protein pp60(v-src); Phorbols; Phosphorylation; Protein Kinase C; Retroviridae Proteins; Ribosomal Protein S6; Ribosomal Proteins; Tetradecanoylphorbol Acetate; Vanadates; Vanadium

1986
Antibodies reactive with the B1 molecule inhibit cell cycle progression but not activation of human B lymphocytes.
    European journal of immunology, 1986, Volume: 16, Issue:8

    Topics: Antibodies, Monoclonal; Antigens, Differentiation, B-Lymphocyte; Antigens, Surface; Calcium; Cell Cycle; Cell Differentiation; Cell Division; Histocompatibility Antigens Class II; Lymphocyte Activation; Phorbols; Time Factors

1986
TPA (12-O-tetradecanoylphorbol-13-acetate) enhances the central hypoglycemic action of thyrotropin-releasing hormone in mice.
    Brain research, 1988, May-31, Volume: 450, Issue:1-2

    Topics: Animals; Blood Glucose; Brain; Dose-Response Relationship, Drug; Hypoglycemia; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Phorbols; Protein Kinase C; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone

1988
Induction of ornithine decarboxylase in guinea-pig lymphocytes. Synergistic effect of diacylglycerol and calcium.
    European journal of biochemistry, 1985, Feb-15, Volume: 147, Issue:1

    Topics: Animals; Calcimycin; Calcium; Calmodulin; Cells, Cultured; Cytosol; Diglycerides; Enzyme Induction; Glycerides; Guinea Pigs; Lymphocytes; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Phytohemagglutinins; Protein Kinase C; Protein Kinases; Type C Phospholipases

1985
Role for protein kinase C in the modulation of glomerular PGE2 production by angiotensin II.
    Biochemical and biophysical research communications, 1988, May-16, Volume: 152, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Dinoprostone; Female; Isoquinolines; Kidney Glomerulus; Phorbol Esters; Phorbols; Piperazines; Prostaglandins E; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1988
Regulation of [3H]phorbol-12,13-dibutyrate binding sites in mouse neuroblastoma cells: simultaneous down-regulation by phorbol esters and desensitization of their inhibition of muscarinic receptor function.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:1

    Topics: Animals; Binding Sites; Carbachol; Clone Cells; Enzyme Activation; Kinetics; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Muscarinic

1988
Phorbol esters inhibit the proliferation of MCF-7 cells. Possible implication of protein kinase C.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Breast Neoplasms; Cell Division; Cell Line; Dose-Response Relationship, Drug; Female; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Tetradecanoylphorbol Acetate

1986
Effects of diacylglycerol and phorbol ester on acetylcholine release and action at the neuromuscular junction in mice.
    British journal of pharmacology, 1987, Volume: 90, Issue:2

    Topics: Animals; Benzylamines; Calcium; Diaphragm; Diglycerides; Electric Stimulation; Glycerides; In Vitro Techniques; Magnesium; Membrane Potentials; Mice; Motor Endplate; Neuromuscular Junction; Pargyline; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phrenic Nerve; Stereoisomerism; Tubocurarine

1987
Phorbol esters inhibit ammoniagenesis and gluconeogenesis in proximal tubular segments.
    The American journal of physiology, 1987, Volume: 252, Issue:6 Pt 2

    Topics: Ammonia; Animals; Dimethyl Sulfoxide; Dogs; Gluconeogenesis; Glutamine; Kidney Tubules, Proximal; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1987
Insulin and phorbol esters affect the maximum velocity rather than the half-saturation constant of 3-O-methylglucose transport in rat adipocytes.
    The Journal of biological chemistry, 1986, Oct-15, Volume: 261, Issue:29

    Topics: 3-O-Methylglucose; Adipose Tissue; Animals; Insulin; Kinetics; Male; Methylglucosides; Methylglycosides; Monosaccharide Transport Proteins; Phorbol Esters; Phorbols; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1986
Effect of phorbol ester on rat liver regeneration.
    Biochemical pharmacology, 1987, Sep-01, Volume: 36, Issue:17

    Topics: Animals; Cell Division; DNA Replication; Liver; Liver Regeneration; Phorbols; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

1987
The 65-kDa phorbol-diester hydrolase in mouse plasma is esterase 1 and is immunologically distinct from the 56-kDa phorbol-diester hydrolase in mouse liver.
    The Journal of biological chemistry, 1985, Dec-15, Volume: 260, Issue:29

    Topics: Animals; Antibody Specificity; Carboxylesterase; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Cross Reactions; Estradiol; Kinetics; Liver; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1985
Co-mitogenic tumor promoters suppress the phosphatidylinositol response in lymphocytes during early mitogenesis.
    Biochimica et biophysica acta, 1985, Feb-08, Volume: 833, Issue:2

    Topics: Animals; Carcinogens; Female; Humans; Lymphocyte Activation; Mice; Phorbol Esters; Phorbols; Phosphates; Phosphatidylcholines; Phosphatidylinositols; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymidine

1985
Sensitization of frog erythrocyte adenylate cyclase system by tumor-promoting phorbol diesters.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:8

    Topics: Adenylyl Cyclases; Animals; Carcinogens; Erythrocyte Membrane; Erythrocytes; Fluorides; Isoproterenol; Kinetics; Manganese; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Rana pipiens; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1985
Acute effects of tumor-promoting phorbol esters on hepatic intermediary metabolism.
    Biochemical and biophysical research communications, 1985, Jun-28, Volume: 129, Issue:3

    Topics: Animals; Fatty Acids; Food; Gluconeogenesis; Glutamine; Ketone Bodies; Liver; Male; Phorbol Esters; Phorbols; Rats; Rats, Inbred Strains; Starvation; Tetradecanoylphorbol Acetate

1985
The role of C-kinase in the physiological activation of the neutrophil oxidase. Evidence from using pharmacological manipulation of C-kinase activity in intact cells.
    The Biochemical journal, 1985, Dec-01, Volume: 232, Issue:2

    Topics: Animals; Diglycerides; Diterpenes; Enzyme Activation; In Vitro Techniques; Latex; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; Neutrophils; Phorbols; Protein Kinase C; Rats; Terpenes; Tetradecanoylphorbol Acetate

1985
Inhibition of histamine-induced acid secretion in rat isolated gastric mucosa by esters of phorbol and 12-deoxyphorbol.
    The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:11

    Topics: Animals; Female; Gastric Acid; Gastric Mucosa; Histamine Antagonists; In Vitro Techniques; Male; Phorbol Esters; Phorbols; Rats; Tetradecanoylphorbol Acetate

1981
Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase.
    The Journal of biological chemistry, 1984, Jul-25, Volume: 259, Issue:14

    Topics: Animals; Diglycerides; Gizzard, Avian; Kinetics; Molecular Weight; Muscle, Smooth; Myosin Subfragments; Myosin-Light-Chain Kinase; Phorbols; Phosphatidylserines; Phosphorylation; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Turkeys

1984
Tumor promoter 12-O-tetradecanoylphorbol 13-acetate stimulates simian virus 40 induction by DNA-damaging agents and tumor initiators.
    Molecular and cellular biology, 1983, Volume: 3, Issue:5

    Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Cells, Cultured; Cricetinae; Mesocricetus; Mitomycin; Mitomycins; Phorbols; Simian virus 40; Tetradecanoylphorbol Acetate; Ultraviolet Rays; Virus Activation

1983
Phorbol diesters stimulate somatostatin secretion from cultured brain cells.
    Endocrinology, 1983, Volume: 113, Issue:1

    Topics: Alkaloids; Animals; Cell Line; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Hypothalamus; Lyngbya Toxins; Peptides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pregnancy; Rats; Tetradecanoylphorbol Acetate; Verapamil

1983
A tumor promoter stimulates phosphorylation on tyrosine.
    Biochemical and biophysical research communications, 1983, Sep-15, Volume: 115, Issue:2

    Topics: Animals; Chick Embryo; Fibroblasts; Molecular Weight; Phorbols; Phosphorylation; Serine; Tetradecanoylphorbol Acetate; Tyrosine

1983
Enhancement by phorbol esters of cell growth inhibiting action of interferon.
    Journal of interferon research, 1984,Fall, Volume: 4, Issue:4

    Topics: 2',5'-Oligoadenylate Synthetase; Cell Division; Cell Line; Cell Transformation, Viral; Drug Resistance; Drug Synergism; Humans; Interferon Type I; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1984
Phorbol esters inhibit agonist-induced [3H] inositol-1-phosphate accumulation in rat hippocampal slices.
    Biochemical and biophysical research communications, 1984, Sep-17, Volume: 123, Issue:2

    Topics: Animals; Caenorhabditis elegans Proteins; Carbachol; Carcinogens; Carrier Proteins; Hippocampus; Inositol; Inositol Phosphates; Male; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Rats; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate

1984
Enhancement of aggregation of Chinese hamster V79 cells in rotation culture by 12-O-tetradecanoylphorbol-13-acetate.
    Cell structure and function, 1983, Volume: 8, Issue:2

    Topics: Animals; Cell Adhesion; Cell Aggregation; Cell Line; Cell Membrane; Cricetinae; Cricetulus; Dimethyl Sulfoxide; Phorbols; Tetradecanoylphorbol Acetate

1983
Preferential growth inhibition of human leukemic versus normal myeloid colony-forming cells by 12-O-tetradecanoylphorbol-13-acetate.
    Experimental hematology, 1984, Volume: 12, Issue:5

    Topics: Cell Differentiation; Cells, Cultured; Hematopoietic Stem Cells; Humans; Leukemia; Phorbols; Tetradecanoylphorbol Acetate

1984
Effects of tumor-promoting agents on cells of the murine immune system: inhibition of antibody synthesis and of macrophage-mediated tumor cell cytotoxicity.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Antibody Formation; B-Lymphocytes; Cytotoxicity, Immunologic; Female; Macrophages; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1982
The effect of phorbols on metabolic cooperation between human fibroblasts.
    Carcinogenesis, 1982, Volume: 3, Issue:10

    Topics: Autoradiography; Cell Communication; Cell Line; Fibroblasts; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Mutation; Phorbols; Tetradecanoylphorbol Acetate; Tritium

1982
Phosphorylation of Gi alpha 2 attenuates inhibitory adenylyl cyclase in neuroblastoma/glioma hybrid (NG-108-15) cells.
    The Journal of biological chemistry, 1994, May-13, Volume: 269, Issue:19

    Topics: Adenylyl Cyclases; Enkephalin, Leucine-2-Alanine; Enzyme Activation; Ethers, Cyclic; Glioma; GTP-Binding Proteins; Hybrid Cells; Naphthalenes; Neuroblastoma; Okadaic Acid; Phorbols; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Phorbol ester-induced M-current suppression in bull-frog sympathetic ganglion cells: insensitivity to kinase inhibitors.
    British journal of pharmacology, 1994, Volume: 113, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Diglycerides; Ganglia, Sympathetic; Isoquinolines; Muscarinic Agonists; Neurons; Patch-Clamp Techniques; Phorbol Esters; Phorbols; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rana catesbeiana; Receptors, Muscarinic; Tetradecanoylphorbol Acetate

1994
[Secretion of peptide YY and truncated glucagon-like peptide 1 by isolated intestinal cells in rats].
    Gastroenterologie clinique et biologique, 1994, Volume: 18, Issue:5

    Topics: Adult; Animals; Calcium-Transporting ATPases; Chromatography, Affinity; Glucagon; Glucagon-Like Peptide 1; Humans; Intestinal Mucosa; Ionomycin; Male; Peptide Fragments; Peptide YY; Peptides; Phorbols; Protein Precursors; Rats; Rats, Wistar; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin

1994
Protein kinase C second messenger system mediates the antisteroidogenic effects of prostaglandin F2 alpha in the ovine corpus luteum in vivo.
    Biology of reproduction, 1994, Volume: 51, Issue:4

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Cholesterol Side-Chain Cleavage Enzyme; Corpus Luteum; Dinoprost; Enzyme Activation; Female; Phorbols; Progesterone; Protein Kinase C; RNA, Messenger; Second Messenger Systems; Sheep; Tetradecanoylphorbol Acetate

1994
Modulation of protein kinase C alters hemodynamics and metabolism in the isolated liver in fed and fasted rats.
    Journal of hepatology, 1993, Volume: 19, Issue:3

    Topics: Alkaloids; Animals; Enzyme Activation; Fasting; Food; Hemodynamics; In Vitro Techniques; Liver; Liver Circulation; Male; Organ Size; Perfusion; Phorbol Esters; Phorbols; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate

1993
Human immunodeficiency virus type 1 Nef protein down-regulates transcription factors NF-kappa B and AP-1 in human T cells in vitro after T-cell receptor stimulation.
    Journal of virology, 1994, Volume: 68, Issue:5

    Topics: Antigens, CD; Base Sequence; Down-Regulation; Gene Products, nef; HIV-1; Humans; Lymphocyte Activation; Molecular Sequence Data; nef Gene Products, Human Immunodeficiency Virus; NF-kappa B; Phorbols; Phytohemagglutinins; Proto-Oncogene Proteins c-jun; Receptors, Cell Surface; Receptors, Cytokine; Signal Transduction; T-Lymphocytes; Transcription Factors

1994
Phorbol ester-induced ventricular fibrillation in the Langendorff-perfused rabbit heart: antagonism by staurosporine and glibenclamide.
    Journal of molecular and cellular cardiology, 1993, Volume: 25, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Diglycerides; Glyburide; Guanidines; Isoquinolines; Perfusion; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pinacidil; Piperazines; Protein Kinase C; Rabbits; Staurosporine; Ventricular Fibrillation

1993
Inhibition of myosin light chain phosphatase during Ca(2+)-independent vasocontraction.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: Animals; Aorta, Thoracic; Calcium; Colforsin; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbols; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Rats; Rats, Wistar; Vasoconstriction; Vasodilator Agents

1993
Monoclonal antibody 8A2-induced retraction appears to be mediated by protein phosphorylation in goldfish retinal ganglion cell axons.
    Developmental biology, 1993, Volume: 156, Issue:1

    Topics: Alkaloids; Animals; Antibodies, Monoclonal; Axons; Calcium; Cyclic AMP; Ethers, Cyclic; Goldfish; Nerve Regeneration; Okadaic Acid; Organ Culture Techniques; Phorbol Esters; Phorbols; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Retinal Ganglion Cells; Staurosporine; Tetradecanoylphorbol Acetate

1993
Further characterization of 5-HT- and 5-HT3 receptor agonists'-stimulated phosphoinositol phosphates accumulation.
    Brain research, 1993, Jul-16, Volume: 617, Issue:1

    Topics: Animals; GTP-Binding Proteins; Inositol Phosphates; Male; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbols; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1993
Feedback regulation of Na channels in rat CCT. IV. Mediation by activation of protein kinase C.
    The American journal of physiology, 1996, Volume: 270, Issue:2 Pt 2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Feedback; Female; Kidney Tubules, Collecting; Male; Ouabain; Patch-Clamp Techniques; Phorbols; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Staurosporine; Tetradecanoylphorbol Acetate; Up-Regulation

1996
Hormone induction of ascorbic acid transport in immature granulosa cells.
    Endocrinology, 1996, Volume: 137, Issue:10

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Ascorbic Acid; Biological Transport; Cellular Senescence; Energy Metabolism; Enzyme Inhibitors; Female; Follicle Stimulating Hormone; Granulosa Cells; Insulin-Like Growth Factor I; Kinetics; Phorbols; Phosphotransferases; Rats; Rats, Sprague-Dawley; Sodium; Time Factors

1996
Restoration of the transient outward potassium current by noradrenaline in chagasic canine epicardium.
    The Journal of physiology, 1997, Apr-01, Volume: 500 ( Pt 1)

    Topics: Animals; Chagas Disease; Dogs; Heart; In Vitro Techniques; Indoles; Isoproterenol; Maleimides; Membrane Potentials; Mice; Mice, Inbred A; Neomycin; Norepinephrine; Patch-Clamp Techniques; Pericardium; Pertussis Toxin; Phorbols; Potassium Channels; Prazosin; Reference Values; Second Messenger Systems; Tetradecanoylphorbol Acetate; Trypanosoma cruzi; Virulence Factors, Bordetella

1997
Opposing effects of phorbol esters on transmitter release and calcium currents at frog motor nerve endings.
    The Journal of physiology, 1997, May-15, Volume: 501 ( Pt 1)

    Topics: Acetylcholine; Animals; Calcium Channel Blockers; Calcium Channels; Electrophysiology; Enzyme Activation; Motor Endplate; Motor Neurons; Nerve Endings; Neurotransmitter Agents; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Potassium Channel Blockers; Protein Kinase C; Rana pipiens

1997
Facilitation of Ca2+ action potential frequency by a small G protein Rab3A in rat pituitary GH3 cells.
    Biochemical and biophysical research communications, 1997, Jun-18, Volume: 235, Issue:2

    Topics: Action Potentials; Animals; Calcium; Enzyme Inhibitors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Patch-Clamp Techniques; Peptide Fragments; Peptides; Phorbol 12,13-Dibutyrate; Phorbols; Pituitary Gland; Protein Kinase C; rab3 GTP-Binding Proteins; rab5 GTP-Binding Proteins; ras Proteins; Rats; Thionucleotides; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured

1997
Protein kinase C activation decreases activity-dependent attenuation of dendritic Na+ current in hippocampal CA1 pyramidal neurons.
    Journal of neurophysiology, 1998, Volume: 79, Issue:1

    Topics: Action Potentials; Animals; Dendrites; Electric Stimulation; Enzyme Activation; Hippocampus; In Vitro Techniques; Male; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium Channels

1998
Protein kinase C disrupts cannabinoid actions by phosphorylation of the CB1 cannabinoid receptor.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Apr-15, Volume: 18, Issue:8

    Topics: Analgesics; Animals; Benzoxazines; Calcium Channel Blockers; Calcium Channels; Cannabinoids; Carcinogens; Cells, Cultured; Enzyme Activation; GTP-Binding Proteins; Hormone Antagonists; Indoles; Maleimides; Morpholines; Mutagenesis; Naphthalenes; omega-Conotoxin GVIA; Peptides; Phorbols; Phosphorylation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Protein Structure, Tertiary; Rats; Receptors, Cannabinoid; Receptors, Drug; Recombinant Fusion Proteins; Serine; Signal Transduction; Somatostatin; Staurosporine; Tetradecanoylphorbol Acetate; Transfection

1998
Ca2+ and protein kinase C activation of mucin granule exocytosis in permeabilized SPOC1 cells.
    The American journal of physiology, 1998, Volume: 275, Issue:1

    Topics: Adenosine Triphosphate; Animals; Bacterial Proteins; Calcium; Cell Line; Cell Membrane Permeability; Cytoplasmic Granules; Enzyme Activation; Exocytosis; Kinetics; Mucins; Mucous Membrane; Phorbols; Protein Kinase C; Rats; Streptolysins; Tetradecanoylphorbol Acetate; Trachea; Uridine Triphosphate

1998
The leukointegrin alpha d/beta 2 (alpha d/CD18): specific changes in surface expression in patients on hemodialysis.
    Cell adhesion and communication, 1998, Volume: 6, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antibodies, Monoclonal; CD11 Antigens; Cell Adhesion; Female; Flow Cytometry; Humans; Integrin alpha Chains; Integrins; Leukocytes, Mononuclear; Macrophages; Male; Mice; Middle Aged; Phorbols; Receptors, Cytoadhesin; Renal Dialysis; Renal Insufficiency; Time Factors

1998
Phosphorylation and IGF-1-mediated dephosphorylation pathways control the activity and the pharmacological properties of skeletal muscle chloride channels.
    British journal of pharmacology, 1998, Volume: 125, Issue:3

    Topics: Animals; Chloride Channels; Culture Techniques; Electric Conductivity; Insulin-Like Growth Factor I; Male; Muscle, Skeletal; Phorbols; Phosphorylation; Phosphotransferases; Rats; Rats, Wistar

1998
Restoration of TEA-induced calcium responses in fibroblasts from Alzheimer's disease patients by a PKC activator.
    Neurobiology of disease, 1998, Volume: 5, Issue:3

    Topics: Alzheimer Disease; Calcium; Carcinogens; Cells, Cultured; Dimethyl Sulfoxide; Enzyme Activation; Excipients; Fibroblasts; Humans; Immunoblotting; Lactams; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Phorbols; Potassium Channels; Protein Kinase C; Tetraethylammonium

1998
Mediation by membrane protein kinase C of zinc-induced oxidative neuronal injury in mouse cortical cultures.
    Journal of neurochemistry, 1999, Volume: 72, Issue:4

    Topics: Animals; Antioxidants; Brain Ischemia; Cell Death; Cells, Cultured; Chromans; Enzyme Inhibitors; Indoles; Lipid Peroxidation; Maleimides; Mice; Nerve Degeneration; Neuroglia; Neurons; Neurotoxins; Oxidative Stress; Phorbols; Protein Kinase C; Thiobarbituric Acid Reactive Substances; Zinc

1999
Activation of PKC disrupts presynaptic inhibition by group II and group III metabotropic glutamate receptors and uncouples the receptor from GTP-binding proteins.
    Annals of the New York Academy of Sciences, 1999, Apr-30, Volume: 868

    Topics: Adenosine; Animals; Dihydropyridines; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Phorbol 12,13-Dibutyrate; Phorbols; Propionates; Protein Kinase C; Receptor, Adenosine A3; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Synaptic Transmission

1999
P-glycoprotein phosphorylation/dephosphorylation and cellular accumulation of L-DOPA in LLC-GA5 Col300 cells.
    Journal of autonomic pharmacology, 1999, Volume: 19, Issue:3

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Epithelium; Humans; Kidney; Levodopa; Okadaic Acid; Phorbols; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Staurosporine; Time Factors; Verapamil

1999
Mechanisms involved in desensitization of particulate guanylyl cyclase in human airway smooth muscle: the role of protein kinase C.
    Biochemical and biophysical research communications, 1999, Dec-09, Volume: 266, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Guanylate Cyclase; Humans; Indoles; Maleimides; Muscle, Smooth; Phorbols; Phosphodiesterase Inhibitors; Protein Kinase C; Respiratory System; Solubility; Tetradecanoylphorbol Acetate; Time Factors

1999
Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters.
    The Journal of biological chemistry, 1999, Dec-10, Volume: 274, Issue:50

    Topics: Acetylcysteine; Animals; Carrier Proteins; Cell Line; Chloroquine; Clathrin; Colforsin; Cycloheximide; Dogs; Dopamine; Dopamine Plasma Membrane Transport Proteins; Endocytosis; Enzyme Activation; Humans; Kinetics; Lysosomes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phorbols; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transfection

1999
Regulation of T cell receptor- and CD28-induced tyrosine phosphorylation of the focal adhesion tyrosine kinases Pyk2 and Fak by protein kinase C. A role for protein tyrosine phosphatases.
    The Journal of biological chemistry, 2000, Jan-14, Volume: 275, Issue:2

    Topics: Antigens, CD; CD28 Antigens; Cell Adhesion Molecules; Cells, Cultured; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Humans; Jurkat Cells; Kinetics; Phorbols; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Vanadates

2000
Functional differences between splice variants of the murine 5-HT(3A) receptor: possible role for phosphorylation.
    Brain research. Molecular brain research, 2000, Sep-30, Volume: 81, Issue:1-2

    Topics: Alternative Splicing; Cell Line; Cyclic AMP; Cyclic GMP; Genetic Variation; Humans; Membrane Potentials; Patch-Clamp Techniques; Phorbols; Phosphorylation; Protein Kinase C; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Tetradecanoylphorbol Acetate; Transfection

2000
Mediation of calcium-independent contraction in trabecular meshwork through protein kinase C and rho-A.
    Investigative ophthalmology & visual science, 2000, Volume: 41, Issue:13

    Topics: Amides; Animals; Blotting, Western; Calcium; Cattle; Cells, Cultured; Chelating Agents; Ciliary Body; Egtazic Acid; Electrophysiology; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Muscle Contraction; Muscle, Smooth; Phorbols; Precipitin Tests; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Tetradecanoylphorbol Acetate; Trabecular Meshwork

2000
Inhibition of depolarisation-evoked [(3)H]noradrenaline release from SH-SYFY human neuroblastoma cells by muscarinic (M1) receptors is not mediated by changes in [Ca(2+)].
    Brain research. Molecular brain research, 2001, Feb-19, Volume: 87, Issue:1

    Topics: Calcium; Elapid Venoms; Estrenes; Humans; Membrane Potentials; Muscarine; Muscarinic Agonists; Neuroblastoma; Neurons; Norepinephrine; Phorbols; Phosphodiesterase Inhibitors; Potassium; Protein Kinase C; Pyrrolidinones; Receptor, Muscarinic M1; Receptors, Muscarinic; Second Messenger Systems; Stimulation, Chemical; Tritium; Tumor Cells, Cultured

2001
Formal synthesis of (+)-phorbol(1).
    Journal of the American Chemical Society, 2001, Jun-13, Volume: 123, Issue:23

    Topics: Carcinogens; Phorbols; Stereoisomerism

2001
Activation of protein kinase C increases acetylcholine release from frog motor nerves by a direct action on L-type Ca(2+) channels and apparently not by depolarisation of the terminal.
    Neuroscience, 2001, Volume: 104, Issue:4

    Topics: Acetylcholine; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Enzyme Inhibitors; Motor Neurons; Naphthalenes; Neuromuscular Junction; Nimodipine; Phorbols; Potassium Chloride; Presynaptic Terminals; Protein Kinase C; Rana temporaria; Staurosporine; Synaptic Transmission; Tetradecanoylphorbol Acetate

2001
Structural investigation of protein kinase C inhibitors.
    Journal of molecular structure, 1991, Volume: 230

    Topics: Gossypol; Lyngbya Toxins; Models, Molecular; Naphthalenes; Perylene; Phorbols; Protein Conformation; Protein Kinase C

1991
Inhibition of the glutamate transporter EAAC1 expressed in Xenopus oocytes by phorbol esters.
    Brain research, 2001, Sep-28, Volume: 914, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Transport System X-AG; Animals; Carcinogens; Carrier Proteins; Cell Membrane; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Indoles; Maleimides; Membrane Potentials; Oocytes; Phorbols; Protein Kinase C; RNA, Complementary; Symporters; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured; Xenopus laevis

2001
P-gp-induced modulation of regulatory volume increase occurs via PKC in mouse proximal tubule.
    American journal of physiology. Renal physiology, 2002, Volume: 282, Issue:1

    Topics: Actin Cytoskeleton; Androstadienes; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Carcinogens; Chromones; Colchicine; Cyclosporine; Cytochalasin B; Diuretics, Osmotic; Enzyme Inhibitors; Hypertonic Solutions; Kidney Tubules, Proximal; Male; Mannitol; Mice; Mice, Knockout; Microtubules; Morpholines; Naphthalenes; Phorbols; Phosphatidylinositol 3-Kinases; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil; Wortmannin

2002
Regulation of high affinity taurine transport in goldfish and rat retinal cells.
    Advances in experimental medicine and biology, 2000, Volume: 483

    Topics: Animals; Biological Transport; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Goldfish; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phorbols; Phosphoprotein Phosphatases; Protein Kinase C; Rats; Retina; Taurine

2000
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives.
    The Journal of biological chemistry, 2002, Apr-19, Volume: 277, Issue:16

    Topics: Animals; Calcium; Cation Transport Proteins; Cell Line; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Electrophysiology; Endothelium, Vascular; Humans; Ion Channels; Kinetics; Mice; Phorbols; Receptors, Drug; Recombinant Proteins; Ruthenium Red; Transfection; TRPV Cation Channels; Tumor Cells, Cultured

2002
Biotransformation of phorbol by human intestinal bacteria.
    Chemical & pharmaceutical bulletin, 2002, Volume: 50, Issue:2

    Topics: Bacteria; Biotransformation; Humans; Intestines; Magnetic Resonance Spectroscopy; Phorbols

2002
4alpha-Phorbol negates the inhibitory effects of phorbol-12-myristate-13-acetate on human cilia and alters the phosphorylation of PKC.
    FEBS letters, 2002, Oct-23, Volume: 530, Issue:1-3

    Topics: Blotting, Western; Cells, Cultured; Cilia; Dose-Response Relationship, Drug; Humans; Indicators and Reagents; Nasal Mucosa; Phorbols; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate

2002
An asymmetric synthesis of aza analogues of the tricyclic skeleton of daphnane and the ABC ring system of phorbol.
    The Journal of organic chemistry, 2003, Feb-07, Volume: 68, Issue:3

    Topics: Aza Compounds; Catalysis; Chemistry, Organic; Crystallography, X-Ray; Cyclization; Diterpenes; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction; Phorbols; Stereoisomerism; Terpenes

2003
Effect of bursal anti-steroidogenic peptide and immunoglobulin G on neonatal chicken B-lymphocyte proliferation.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2003, Volume: 134, Issue:3

    Topics: Animals; Animals, Newborn; B-Lymphocytes; Bursa of Fabricius; Cell Division; Cells, Cultured; Chickens; DNA; Immunoglobulin Fab Fragments; Immunoglobulin Fc Fragments; Immunoglobulin G; Peptides; Phorbols; Rabbits; Steroids

2003
Protein kinase C is involved in clozapine's facilitation of N-methyl-D-aspartate- and electrically evoked responses in pyramidal cells of the medial prefrontal cortex.
    Neuroscience, 2003, Volume: 118, Issue:2

    Topics: Alkaloids; Animals; Benzophenanthridines; Clozapine; Drug Interactions; Electric Stimulation; Electrophysiology; Enzyme Activators; Enzyme Inhibitors; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Fluorobenzenes; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Mice, Knockout; Mice, Mutant Strains; N-Methylaspartate; Peptide Fragments; Phenanthridines; Phorbols; Piperidines; Protein Kinase C; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tetradecanoylphorbol Acetate; Time Factors

2003
Models of anergy in the human Jurkat T cell line.
    Assay and drug development technologies, 2003, Volume: 1, Issue:4

    Topics: Calcium; CD28 Antigens; CD3 Complex; Clonal Anergy; Down-Regulation; Genes, T-Cell Receptor; Humans; Hydrogen Peroxide; Interleukin-2; Jurkat Cells; Models, Immunological; Muromonab-CD3; Phorbols; Polymerase Chain Reaction; Signal Transduction; T-Lymphocytes

2003
Evidence for biphasic effects of protein kinase C on serotonin transporter function, endocytosis, and phosphorylation.
    Molecular pharmacology, 2005, Volume: 67, Issue:6

    Topics: Animals; Dose-Response Relationship, Drug; Endocytosis; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Nerve Tissue Proteins; Phorbols; Phosphorylation; Protein Kinase C; Rats; Serotonin; Serotonin Plasma Membrane Transport Proteins

2005
Induction of long-term depression and phosphorylation of the delta2 glutamate receptor by protein kinase C in cerebellar slices.
    The European journal of neuroscience, 2005, Volume: 22, Issue:7

    Topics: Animals; Animals, Newborn; Blotting, Western; Cerebellum; Electrophoresis; Electrophoresis, Gel, Two-Dimensional; In Vitro Techniques; Long-Term Synaptic Depression; Mice; Molecular Sequence Data; Patch-Clamp Techniques; Phorbols; Phosphorylation; Protein Kinase C; Receptors, Glutamate

2005
Functional expression of transient receptor potential vanilloid 4 in the mouse cochlea.
    Neuroreport, 2006, Feb-06, Volume: 17, Issue:2

    Topics: Animals; Blotting, Northern; Blotting, Western; Calcium; Chelating Agents; Cochlea; Drug Interactions; Egtazic Acid; Gene Expression Regulation; Hypotonic Solutions; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Phorbols; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ruthenium Red; TRPV Cation Channels

2006
Effect of gamma-linolenic acid and prostaglandins E1 on gamma-radiation and chemical-induced genetic damage to the bone marrow cells of mice.
    Prostaglandins, leukotrienes, and essential fatty acids, 2006, Volume: 74, Issue:3

    Topics: Alprostadil; Animals; Benzo(a)pyrene; Bone Marrow Cells; Chromosome Aberrations; Erythroblasts; Gamma Rays; gamma-Linolenic Acid; Male; Mice; Micronucleus Tests; Mutagens; Phenytoin; Phorbols; Reticulocytes

2006
Increases in vanilloid TRPV1 receptor protein and CGRP content during endotoxemia in rats.
    European journal of pharmacology, 2007, Jul-02, Volume: 566, Issue:1-3

    Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Endocannabinoids; Endotoxemia; Lipopolysaccharides; Male; Mesentery; Norepinephrine; Phorbols; Polyunsaturated Alkamides; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tongue; TRPV Cation Channels; Vasoconstrictor Agents; Vasodilation

2007
Suppression of aromatase in human breast cells by a cyclooxygenase-2 inhibitor and its analog involves multiple mechanisms independent of cyclooxygenase-2 inhibition.
    Steroids, 2008, Volume: 73, Issue:1

    Topics: Aromatase; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colforsin; Cyclooxygenase 2 Inhibitors; Dexamethasone; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Microsomes; Molecular Structure; Nitrobenzenes; Phorbols; Sulfonamides; Testosterone

2008
Practical synthesis of prostratin, DPP, and their analogs, adjuvant leads against latent HIV.
    Science (New York, N.Y.), 2008, May-02, Volume: 320, Issue:5876

    Topics: Anti-HIV Agents; Chemotherapy, Adjuvant; HIV-1; Humans; Models, Molecular; Phorbol Esters; Phorbols; Viral Load; Virus Latency

2008
Phorbol 12-myristate 13-acetate inhibits FRO anaplastic human thyroid cancer cell proliferation by inducing cell cycle arrest in G1/S phase: evidence for an effect mediated by PKCdelta.
    Molecular and cellular endocrinology, 2008, Sep-24, Volume: 292, Issue:1-2

    Topics: Carcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Forkhead Box Protein O1; Forkhead Transcription Factors; G1 Phase; Humans; Isoenzymes; Mitogen-Activated Protein Kinases; Phorbols; Phosphorylation; Protein Kinase C-delta; Protein Transport; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; S Phase; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Transfection

2008
Regulation of the benzamil-insensitive salt taste receptor by intracellular Ca2+, protein kinase C, and calcineurin.
    Journal of neurophysiology, 2009, Volume: 102, Issue:3

    Topics: Amiloride; Animals; Benzamides; Calcineurin; Calcium; Chelating Agents; Chorda Tympani Nerve; Diterpenes; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Extracellular Fluid; Female; Gene Expression Regulation; Mice; Mice, Inbred C57BL; Mice, Knockout; Phorbols; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium Chloride; Taste; Taste Buds; Taste Threshold; TRPV Cation Channels

2009
Calcium-dependent signalling is essential during collateral growth in the pig hind limb-ischemia model.
    Journal of molecular and cellular cardiology, 2010, Volume: 49, Issue:1

    Topics: Animals; Aorta; Arteries; Blood Vessels; Calcium Signaling; Femoral Artery; Hindlimb; Ischemia; Lower Extremity; Male; NFATC Transcription Factors; Phorbols; Random Allocation; Stress, Mechanical; Sus scrofa

2010
Molecular regulation of NADPH oxidase 5 via the MAPK pathway.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:4

    Topics: Butadienes; Calcium; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Ionomycin; Ionophores; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Membrane Proteins; Mitogen-Activated Protein Kinases; NADPH Oxidase 5; NADPH Oxidases; Nitriles; Phorbols; Phosphorylation; Protein Kinase C; RNA, Small Interfering

2011
A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis.
    Molecular and cellular biology, 2012, Volume: 32, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cell Movement; Cell Transformation, Neoplastic; Cytoskeleton; Disease Progression; Endothelial Cells; Focal Adhesion Protein-Tyrosine Kinases; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Neovascularization, Pathologic; Papilloma; Phorbols; Protein Serine-Threonine Kinases; Skin Neoplasms; Vascular Endothelial Growth Factor Receptor-2

2012
Two new tigliane diterpene esters from the flower buds of Daphne genkwa.
    Journal of Asian natural products research, 2013, Volume: 15, Issue:5

    Topics: Daphne; Diterpenes; Drugs, Chinese Herbal; Esters; Flowers; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phorbols

2013
Mechanisms of resveratrol-induced changes in [Ca(2+)]i and cell viability in PC3 human prostate cancer cells.
    Journal of receptor and signal transduction research, 2013, Volume: 33, Issue:5

    Topics: Apoptosis; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Proliferation; Cell Survival; Homeostasis; Humans; Male; Phorbols; Prostatic Neoplasms; Protein Kinase C; Protein Kinase Inhibitors; Resveratrol; Stilbenes

2013
Modulation of COX, LOX and NFκB activities by Xanthium spinosum L. root extract and ziniolide.
    Fitoterapia, 2013, Volume: 91

    Topics: Anti-Inflammatory Agents; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; HeLa Cells; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Inhibitory Concentration 50; Lipoxygenase Inhibitors; Lipoxygenases; NF-kappa B; Phorbols; Phytotherapy; Plant Extracts; Plant Roots; Sesquiterpenes, Guaiane; Xanthium

2013
Alienusolin, a new 4α-deoxyphorbol ester derivative, and crotonimide C, a new glutarimide alkaloid from the Kenyan Croton alienus.
    Planta medica, 2013, Volume: 79, Issue:18

    Topics: Aedes; Alkaloids; Animals; Anopheles; Anti-Infective Agents; Bacteria; Benzamides; Cell Survival; Chlorocebus aethiops; Croton; Esters; Fungi; Leishmania; Medicine, African Traditional; Molecular Structure; Phorbol Esters; Phorbols; Piperidones; Plant Leaves; Plant Roots; Plants, Medicinal; Plasmodium falciparum; Vero Cells

2013
Palmitate-stimulated monocytes induce adhesion molecule expression in endothelial cells via IL-1 signaling pathway.
    Journal of cellular physiology, 2015, Volume: 230, Issue:3

    Topics: Cell Adhesion Molecules; E-Selectin; Endothelial Cells; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Monocytes; Palmitates; Phorbols; Signal Transduction

2015
Synthesis of a des-B-ring bryostatin analogue leads to an unexpected ring expansion of the bryolactone core.
    Journal of the American Chemical Society, 2014, Sep-24, Volume: 136, Issue:38

    Topics: Animals; Antineoplastic Agents; Biological Products; Bryostatins; Bryozoa; Cell Line, Tumor; Humans; Models, Molecular; Phorbols; Protein Kinase C

2014
Nineteen-step total synthesis of (+)-phorbol.
    Nature, 2016, Apr-07, Volume: 532, Issue:7597

    Topics: Bicyclic Monoterpenes; Biological Products; Chemistry Techniques, Synthetic; Diterpenes; Molecular Structure; Monoterpenes; Oxygen; Phorbol Esters; Phorbols; Stereoisomerism

2016
Functional Expression of an Osmosensitive Cation Channel, Transient Receptor Potential Vanilloid 4, in Rat Vestibular Ganglia.
    Audiology & neuro-otology, 2016, Volume: 21, Issue:4

    Topics: Animals; Calcium; Ganglia, Sensory; Neurons; Phorbols; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; TRPV Cation Channels; Vestibular Nerve

2016
RAS-Mitogen-Activated Protein Kinase Signal Is Required for Enhanced PD-L1 Expression in Human Lung Cancers.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; B7-H1 Antigen; Butadienes; Cell Adhesion; Cell Movement; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Mutation; Nitriles; Phorbols; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); RNA, Small Interfering; STAT3 Transcription Factor; Transcription Factor AP-1; Transcription Initiation Site

2016
Identification of proximal biomarkers of PKC agonism and evaluation of their role in HIV reactivation.
    Antiviral research, 2017, Volume: 139

    Topics: Biomarkers; CD4-Positive T-Lymphocytes; Cells, Cultured; Diterpenes; Drug Agonism; Early Growth Response Protein 1; Early Growth Response Protein 3; Gene Expression; HIV Infections; HIV-1; Humans; Jurkat Cells; Male; Phorbols; Protein Kinase C; Sequence Analysis, RNA; Virus Activation; Virus Latency

2017
Isolation and characterisation of cytotoxic compounds from Euphorbia clementei Boiss.
    Natural product research, 2017, Volume: 31, Issue:18

    Topics: Antineoplastic Agents, Phytogenic; Diterpenes; Drug Screening Assays, Antitumor; Euphorbia; HL-60 Cells; Humans; Inhibitory Concentration 50; K562 Cells; Latex; Magnetic Resonance Spectroscopy; Molecular Structure; Phorbols; Plant Roots; Spectrometry, Mass, Electrospray Ionization

2017
Phorbol 12-myristate 13-acetate stimulation under hypoxia induces nuclear swelling with DNA outflow but not extracellular trap formation of neutrophils.
    Experimental and molecular pathology, 2022, Volume: 125

    Topics: Acetates; DNA; Extracellular Traps; Histones; Humans; Hypoxia; Lung Diseases; Myristic Acid; Neutrophils; Phorbols; Tetradecanoylphorbol Acetate

2022
Bioinformatics of Differentially Expressed Genes in Phorbol 12-Myristate 13-Acetate-Induced Megakaryocytic Differentiation of K562 Cells by Microarray Analysis.
    International journal of molecular sciences, 2022, Apr-11, Volume: 23, Issue:8

    Topics: Acetates; Cell Differentiation; Computational Biology; Humans; K562 Cells; Megakaryocytes; Microarray Analysis; Myristic Acid; Phorbols; Tetradecanoylphorbol Acetate; Thrombopoiesis

2022
Biphasic alcoholysis coupled with high-speed countercurrent chromatography for high performance on separating phorbol from Croton tiglium Linn extracts.
    Journal of separation science, 2023, Volume: 46, Issue:8

    Topics: Chromatography, High Pressure Liquid; Countercurrent Distribution; Croton Oil; Phorbol Esters; Phorbols; Plant Extracts; Solvents

2023
Insertion Depth Modulates Protein Kinase C-δ-C1b Domain Interactions with Membrane Cholesterol as Revealed by MD Simulations.
    International journal of molecular sciences, 2023, Feb-27, Volume: 24, Issue:5

    Topics: Bryostatins; Humans; Isoenzymes; Lactones; Phorbol Esters; Phorbols; Protein Kinase C-delta

2023