phorbols has been researched along with isoproterenol in 32 studies
| Studies (phorbols) | Trials (phorbols) | Recent Studies (post-2010) (phorbols) | Studies (isoproterenol) | Trials (isoproterenol) | Recent Studies (post-2010) (isoproterenol) |
|---|---|---|---|---|---|
| 2,217 | 0 | 72 | 30,780 | 803 | 2,640 |
| Protein | Taxonomy | phorbols (IC50) | isoproterenol (IC50) |
|---|---|---|---|
| Beta-2 adrenergic receptor | Homo sapiens (human) | 0.246 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 0.333 | |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 1.77 | |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Beta-3 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Beta-2 adrenergic receptor | Canis lupus familiaris (dog) | 0.6667 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (96.88) | 18.7374 |
| 1990's | 1 (3.13) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boutwell, RK; Mufson, RA; Simsiman, RC | 1 |
| Astrup, EG; Boutwell, RK; Mufson, RA; Simsiman, RC | 1 |
| Boutwell, RK; Fischer, SM; Gleason, GL; Mufson, RA; Slaga, TJ; Verma, AK | 1 |
| Choi, EJ; Toscano, WA | 1 |
| Bell, JD; Brunton, LL; Buxton, IL | 1 |
| Zatz, M | 1 |
| Fishman, PH; Kassis, S; Patel, J; Zaremba, T | 1 |
| Dan'ura, T; Higashi, K; Ishibashi, S; Kurokawa, T; Yamashita, A | 1 |
| Limas, C; Limas, CJ | 1 |
| Garte, SJ | 1 |
| Grubbs, RD; Maguire, ME | 1 |
| Brown, JH; Harden, TK; Heng, MM | 1 |
| Kato, R; Uzumaki, H; Yamamoto, S | 1 |
| Lefkowitz, RJ; Nambi, P; Sibley, DR | 1 |
| Dale, MM; Obianime, W | 1 |
| Johnson, GL; Kelleher, DJ; Pessin, JE; Ruoho, AE | 1 |
| Belman, S; Garte, SJ | 4 |
| Ganss, M; Grimm, W; Marks, F | 1 |
| Marks, F | 2 |
| Link, R; Marks, F | 1 |
| Murray, AW; Solanki, V | 2 |
| Sachs, L; Simantov, R | 1 |
| Belman, S; Fennikoh, KB; Garte, SJ | 1 |
| Belman, S; Currie, D; Garte, SJ | 1 |
| Lefkowitz, RJ; Nambi, P; Peters, JR; Sibley, DR | 1 |
| Novogrodsky, A; Patya, M; Rubin, AL; Stenzel, KH | 1 |
| Barr, SC; Gilmour, RF; Han, W; Pacioretty, LM | 1 |
32 other study(ies) available for phorbols and isoproterenol
| Article | Year |
|---|---|
The effect of the phorbol ester tumor promoters on the basal and catecholamine-stimulated levels of cyclic adenosine 3':5'-monophosphate in mouse skin and epidermis in vivo.
Topics: Animals; Cyclic AMP; Epinephrine; Female; Isoproterenol; Methods; Mice; Phorbols; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Skin; Tetradecanoylphorbol Acetate | 1977 |
Dissociation of increases in levels of 3':5'-cyclic AMP and 3':5'-cyclic GMP from induction of ornithine decarboxylase by the tumor promoter 12-O-tetradecanoyl phorbol-13-acetate in mouse epidermis in vivo.
Topics: Animals; Carboxy-Lyases; Cyclic AMP; Cyclic GMP; Enzyme Induction; Female; Isoproterenol; Kinetics; Mice; Ornithine Decarboxylase; Phorbols; Skin; Tetradecanoylphorbol Acetate | 1977 |
Effects of 12-O-tetradecanoylphorbol-13-acetate and mezerein on epidermal ornithine decarboxylase activity, isoproterenol-stimulated levels of cyclic adenosine 3':5'-monophosphate, and induction of mouse skin tumors in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Division; Cyclic AMP; Dermatitis, Contact; Diterpenes; Female; Isoproterenol; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Modulation of adenylate cyclase in human keratinocytes by protein kinase C.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Line; Epidermis; Humans; Isoproterenol; Keratins; Pertussis Toxin; Phorbol Esters; Phorbols; Propranolol; Protein Kinase C; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol esters. Putative effect of C kinase on alpha s-GTP-catalytic subunit interaction.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Cyclic AMP; Drug Synergism; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Lymphoma; Manganese; Phorbols; Protein Kinase C; Protein Kinases; Somatostatin; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Phorbol esters mimic alpha-Adrenergic potentiation of serotonin N-acetyltransferase induction in the rat pineal.
Topics: Acetyltransferases; Adrenergic alpha-Agonists; Animals; Arylamine N-Acetyltransferase; Enzyme Induction; Isoproterenol; Male; Phenylephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pineal Gland; Rats; Rats, Inbred Strains | 1985 |
Phorbol esters and beta-adrenergic agonists mediate desensitization of adenylate cyclase in rat glioma C6 cells by distinct mechanisms.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cells, Cultured; Concanavalin A; Enzyme Activation; Glioma; Isoproterenol; Phorbols; Phosphorylation; Protein Kinase C; Protein Kinases; Rats; Receptors, Adrenergic, beta; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1985 |
Induction of desensitization by phorbol ester to beta-adrenergic agonist stimulation in adenylate cyclase system of rat reticulocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Diglycerides; Guanylyl Imidodiphosphate; Isoproterenol; Isoquinolines; Male; Phorbols; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Reticulocytes; Tetradecanoylphorbol Acetate | 1986 |
Phorbol ester- and diacylglycerol-mediated desensitization of cardiac beta-adrenergic receptors.
Topics: Animals; Colchicine; Diglycerides; Glycerides; Heart; In Vitro Techniques; Isoproterenol; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1985 |
Differential effects of phorbol ester on the beta-adrenergic response of normal and ras-transformed NIH3T3 cells.
Topics: Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; DNA, Neoplasm; Fibroblasts; Humans; Isoproterenol; Mice; Mice, Nude; Oncogenes; Phenotype; Phorbols; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms | 1985 |
Regulation of magnesium but not calcium transport by phorbol ester.
Topics: Animals; Biological Transport, Active; Calcium; Cell Line; Colforsin; Cyclic AMP; Isoproterenol; Kinetics; Lymphoma; Magnesium; Phorbols; Phosphorylation; Tetradecanoylphorbol Acetate | 1986 |
Receptor reserve in the calcium-dependent cyclic AMP response of astrocytoma cells to muscarinic receptor stimulation: demonstration by agonist-induced desensitization, receptor inactivation, and phorbol ester treatment.
Topics: Astrocytoma; Calcium; Carbachol; Cells, Cultured; Cyclic AMP; Inositol Phosphates; Isoproterenol; Oxotremorine; Phorbols; Propylbenzilylcholine Mustard; Receptors, Muscarinic; Tetradecanoylphorbol Acetate | 1986 |
Effects of lipoxygenase and cyclooxygenase inhibitors on the induction of ornithine decarboxylase by 12-O-tetradecanoylphorbol-13-acetate and isoproterenol in mouse tissues in vivo.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Benzoquinones; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Induction; Female; Indomethacin; Isoproterenol; Kidney; Lipoxygenase Inhibitors; Liver; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Phorbols; Pyrazoles; Quinones; Spleen; Tetradecanoylphorbol Acetate | 1986 |
Sensitization of frog erythrocyte adenylate cyclase system by tumor-promoting phorbol diesters.
Topics: Adenylyl Cyclases; Animals; Carcinogens; Erythrocyte Membrane; Erythrocytes; Fluorides; Isoproterenol; Kinetics; Manganese; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Rana pipiens; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1985 |
Phorbol myristate acetate causes in guinea-pig lung parenchymal strip a maintained spasm which is relatively resistant to isoprenaline.
Topics: Aminophylline; Animals; Colforsin; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Lung; Male; Muscle Contraction; Muscle, Smooth; Nitroprusside; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the beta-adrenergic receptor in turkey erythrocytes.
Topics: Adenylyl Cyclases; Animals; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Phorbols; Phosphorylation; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Thionucleotides; Time Factors; Turkeys | 1984 |
Decreased beta-adrenergic responsiveness in mouse epidermal papillomas during tumor promotion with phorbol myristate acetate.
Topics: Adrenergic beta-Agonists; Animals; Cyclic AMP; Female; Isoproterenol; Mice; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Agonist- and mitogen-induced desensitization of isoproterenol-stimulated cyclic AMP formation in mouse epidermis in vivo.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcimycin; Catecholamines; Cyclic AMP; Epidermis; Female; Isoproterenol; Mice; Mitogens; Phorbol Esters; Phorbols; Phosphoric Diester Hydrolases; Tetradecanoylphorbol Acetate | 1981 |
Prevention of phorbol ester-induced catecholamine refractoriness by inhibitors of protein and RNA biosynthesis in mouse epidermis in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Catecholamines; Cyclic AMP; Cycloheximide; Female; Fluorides; Isoproterenol; Kinetics; Mice; Phorbols; Skin; Tetradecanoylphorbol Acetate; Theophylline | 1980 |
Antagonism between phorbol myristate acetate and butyric acid on isoproterenol elevation of cyclic adenosine 3':5'-monophosphate and their effects on beta-adrenergic receptors in mouse epidermis.
Topics: Animals; Butyrates; Cyclic AMP; Female; Isoproterenol; Mice; Phorbols; Receptors, Adrenergic; Receptors, Adrenergic, beta; Skin; Tetradecanoylphorbol Acetate | 1980 |
Tumour promoter uncouples beta-adrenergic receptor from adenyl cyclase in mouse epidermis.
Topics: Adenylyl Cyclases; Animals; Cell-Free System; Cyclic AMP; Enzyme Activation; Epidermis; Female; Guanosine Triphosphate; Isoproterenol; Membrane Fluidity; Mice; Phorbols; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1980 |
Histone phosphorylation in phorbol ester stimulated and beta-adrenergically stimulated mouse epidermis in vivo and characterization of an epidermal protein phosphorylation system.
Topics: Animals; Casein Kinases; Epidermis; Female; Histones; Isoproterenol; Mice; Phorbols; Phosphoprotein Phosphatases; Phosphorylation; Protamine Kinase; Protein Kinases; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1981 |
Phorbol myristate acetate uncouples the relationship between beta-adrenergic receptors and adenyl cyclase in mouse epidermis: a phenotypic trait in papillomas.
Topics: Adenylyl Cyclases; Animals; Cocarcinogenesis; Cyclic GMP; Enzyme Activation; Epidermis; Isoproterenol; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Receptors, Adrenergic; Receptors, Adrenergic, beta; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Decreased accumulation of cyclic adenosine 3',5'-monophosphate in "ischemic" skin after 12-0-tetradecanoyl-phorbol-13-acetate treatment.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acetone; Adenosine; Animals; Cyclic AMP; Dinoprostone; Female; Histamine; In Vitro Techniques; Ischemia; Isoproterenol; Mice; Phorbols; Prostaglandins E; Skin; Tetradecanoylphorbol Acetate | 1982 |
Enhancement of hormone action by a phorbol ester and anti-tubulin alkaloids involves different mechanisms.
Topics: Alprostadil; Animals; Antineoplastic Agents, Phytogenic; Cell Line; Clone Cells; Cyclic AMP; Diterpenes; Isoproterenol; Kinetics; Leukemia, Experimental; Mice; Phorbol Esters; Phorbols; Prostaglandins E; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Comparison of the effects of age and phorbol myristate acetate on the beta-adrenergic system in mouse epidermis.
Topics: Aging; Animals; Cyclic AMP; Epidermis; Female; Isoproterenol; Mice; Mice, Inbred ICR; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Inhibition of beta-adrenergic response in cultured epidermal cells by phorbol myristate acetate.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cyclic AMP; Isoproterenol; Mice; Mice, Inbred C57BL; Phorbols; Receptors, Adrenergic; Receptors, Adrenergic, beta; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate | 1983 |
Effect of 12-O-tetradecanoyl-phorbol-13-acetate on beta-adrenergic receptors of newborn mouse skin.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Enzyme Activation; Isoproterenol; Mice; Phorbols; Receptors, Adrenergic; Receptors, Adrenergic, beta; Skin; Tetradecanoylphorbol Acetate | 1982 |
Prostaglandins, cyclic nucleotides and the effect of phorbol ester tumor promoters on mouse skin in vivo.
Topics: Animals; Cyclic AMP; Female; Isoproterenol; Kinetics; Mice; Mice, Inbred Strains; Phorbol Esters; Phorbols; Prostaglandins; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1983 |
Phorbol diesters promote beta-adrenergic receptor phosphorylation and adenylate cyclase desensitization in duck erythrocytes.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Affinity Labels; Animals; Ducks; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Isoproterenol; Phorbol Esters; Phorbols; Phosphorylation; Photochemistry; Receptors, Adrenergic, beta | 1984 |
Inhibition of beta-adrenergic stimulation of lymphocyte adenylate cyclase by phorbol myristate acetate is mediated by activated macrophages.
Topics: Adenylyl Cyclases; Animals; Catalase; Erythrocyte Membrane; Heme; Humans; Isoproterenol; Lymphocytes; Macrophages; Phorbols; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Turkeys | 1982 |
Restoration of the transient outward potassium current by noradrenaline in chagasic canine epicardium.
Topics: Animals; Chagas Disease; Dogs; Heart; In Vitro Techniques; Indoles; Isoproterenol; Maleimides; Membrane Potentials; Mice; Mice, Inbred A; Neomycin; Norepinephrine; Patch-Clamp Techniques; Pericardium; Pertussis Toxin; Phorbols; Potassium Channels; Prazosin; Reference Values; Second Messenger Systems; Tetradecanoylphorbol Acetate; Trypanosoma cruzi; Virulence Factors, Bordetella | 1997 |