Page last updated: 2024-09-04

phorbols and dactinomycin

phorbols has been researched along with dactinomycin in 20 studies

Compound Research Comparison

Studies
(phorbols)
Trials
(phorbols)
Recent Studies (post-2010)
(phorbols)
Studies
(dactinomycin)
Trials
(dactinomycin)
Recent Studies (post-2010) (dactinomycin)
2,21707219,045355969

Protein Interaction Comparison

ProteinTaxonomyphorbols (IC50)dactinomycin (IC50)
RAD51Homo sapiens (human)32.1
Growth factor receptor-bound protein 2Homo sapiens (human)5
Discoidin domain-containing receptor 2Homo sapiens (human)9
Growth factor receptor-bound protein 2 Mus musculus (house mouse)5

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199020 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boutwell, RK; O'Brien, TG; Simsiman, RC1
Reich, E; Wilson, EL1
Fibach, E; Marks, PA; Rifkind, RA; Weinstein, IB; Yamasaki, H1
Lee, LS; Weinstein, IB1
Kensler, TW; Mueller, GC; Wertz, PW1
Mueller, GC; Wertz, PW1
Beaudry, GA; Daniel, LW; Waite, M1
Buckley, AR; Putnam, CW; Russell, DH1
Enomoto, T; Kanno, Y; Martel, N; Shiba, Y; Yamasaki, H1
Grotendorst, GR; Schimmel, SD1
Jaffe, E; Moscatelli, D; Rifkin, DB1
Arya, SK; Gallo, RC1
Scher, W; Waxman, S1
Bissell, MJ; Laszlo, A1
Matsui-Yuasa, I; Morisawa, S; Otani, S; Shu, ZW1
AbdAllah, NA; Fisch, H; Flick, DA; Gifford, GE1
Bonney, RJ; Dahlgren, ME; Davies, P; Humes, JL; Kuehl, FA; Wightman, PD1
Gambari, R1
Byus, CV; Wu, VS1
Bisschop, A; Derks, HJ; van Rooijen, LA; van Wijk, R1

Other Studies

20 other study(ies) available for phorbols and dactinomycin

ArticleYear
Induction of the polyamine-biosynthetic enzymes in mouse epidermis by tumor-promoting agents.
    Cancer research, 1975, Volume: 35, Issue:7

    Topics: Adenosylmethionine Decarboxylase; Animals; Azacitidine; Carboxy-Lyases; Carcinogens; Chick Embryo; Croton Oil; Cycloheximide; Dactinomycin; Deoxyadenosines; Dose-Response Relationship, Drug; Enzyme Induction; Female; Half-Life; Mice; Ornithine Decarboxylase; Phorbols; RNA; Skin; Time Factors

1975
Plasminogen activator in chick fibroblasts: induction of synthesis by retinoic acid; synergism with viral transformation and phorbol ester.
    Cell, 1978, Volume: 15, Issue:2

    Topics: Animals; Cell Transformation, Viral; Cells, Cultured; Cyclic AMP; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Genes, Viral; Kinetics; Phorbols; Sarcoma, Experimental; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A

1978
Tumor promoter-induced adhesion of the DS19 clone of murine erythroleukemia cells.
    Cancer research, 1979, Volume: 39, Issue:6 Pt 1

    Topics: Animals; Cell Adhesion; Cell Differentiation; Clone Cells; Cold Temperature; Dactinomycin; Drug Resistance; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1979
Epidermal growth factor, like phorbol esters, induces plasminogen activator in HeLa cells.
    Nature, 1978, Aug-17, Volume: 274, Issue:5672

    Topics: Cycloheximide; Dactinomycin; Epidermal Growth Factor; HeLa Cells; Peptides; Phorbols; Plasminogen Activators; Tetradecanoylphorbol Acetate

1978
Inhibition of phorbol ester-accelerated amino acid transport in bovine lymphocytes.
    Biochimica et biophysica acta, 1979, Jun-01, Volume: 585, Issue:1

    Topics: Aminoisobutyric Acids; Animals; Biological Transport, Active; Cattle; Cycloheximide; Dactinomycin; In Vitro Techniques; Lymphocytes; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin

1979
Rapid stimulation of phospholipid metabolism in bovine lymphocytes by tumor-promoting phorbol esters.
    Cancer research, 1978, Volume: 38, Issue:9

    Topics: Cells, Cultured; Choline; Cycloheximide; Cytochalasin B; Dactinomycin; Drug Interactions; Lectins; Lymphocyte Activation; Lymphocytes; Phorbol Esters; Phorbols; Phospholipids; Tetradecanoylphorbol Acetate; Tretinoin

1978
Regulation of arachidonic acid metabolism in Madin-Darby canine kidney cells: stimulation of synthesis of the cyclooxygenase system by 12-O-tetradecanoyl-phorbol-13-acetate.
    Archives of biochemistry and biophysics, 1985, May-15, Volume: 239, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cycloheximide; Dactinomycin; Dogs; Enzyme Induction; Kidney; Kinetics; Phorbols; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate

1985
In vivo induction of rat hepatic ornithine decarboxylase and plasminogen activator by 12-O-tetradecanoylphorbol 13-acetate.
    Biochimica et biophysica acta, 1985, Jul-26, Volume: 841, Issue:1

    Topics: Animals; Cycloheximide; Dactinomycin; Enzyme Induction; Liver; Ornithine Decarboxylase; Phorbols; Plasminogen Activators; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1985
Tumour promoter-mediated reversible inhibition of cell-cell communication (electrical coupling). Relationship with phorbol ester binding and de novo macromolecule synthesis.
    Experimental cell research, 1983, Volume: 146, Issue:2

    Topics: Binding Sites; Cell Communication; Cell Line; Cycloheximide; Dactinomycin; Diterpenes; Electrophysiology; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Biosynthesis; RNA; Terpenes; Tetradecanoylphorbol Acetate

1983
Alteration of cyclic nucleotide levels in phorbol 12-myristate 13-acetate treated myoblasts.
    Biochemical and biophysical research communications, 1980, Mar-13, Volume: 93, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aminophylline; Animals; Biological Transport, Active; Cells, Cultured; Chick Embryo; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Deoxyglucose; Kinetics; Muscles; Phorbols; Tetradecanoylphorbol Acetate; Theophylline

1980
Tetradecanoyl phorbol acetate stimulates latent collagenase production by cultured human endothelial cells.
    Cell, 1980, Volume: 20, Issue:2

    Topics: Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Endothelium; Humans; Microbial Collagenase; Phorbols; Plasminogen Activators; Plasminogen Inactivators; Tetradecanoylphorbol Acetate

1980
Transcriptional modulation of human T-cell growth factor gene by phorbol ester and interleukin 1.
    Biochemistry, 1984, Dec-18, Volume: 23, Issue:26

    Topics: Cells, Cultured; Dactinomycin; Genes; Humans; Interleukin-1; Interleukin-2; Phorbols; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1984
Effects of dexamethasone and phorbol myristate acetate on the induction of differentiation in mouse erythroleukemic cells by dimethyl sulfoxide, proteases, and other compounds.
    Annals of the New York Academy of Sciences, 1983, Volume: 411

    Topics: Animals; Cell Differentiation; Cell Division; Dactinomycin; Dexamethasone; Dimethyl Sulfoxide; Leukemia, Erythroblastic, Acute; Mice; Peptide Hydrolases; Phorbols; Tetradecanoylphorbol Acetate

1983
TPA induces simultaneous alterations in the synthesis and organization of vimentin.
    Experimental cell research, 1983, Volume: 148, Issue:1

    Topics: Animals; Cells, Cultured; Chick Embryo; Cytoskeleton; Dactinomycin; Fluorescent Antibody Technique; Intermediate Filament Proteins; Kinetics; Microtubules; Phorbols; Tetradecanoylphorbol Acetate; Vimentin

1983
Phorbol esters stimulate spermidine/spermine N1-acetyltransferase activity in mitogen-stimulated bovine lymphocytes.
    FEBS letters, 1984, Dec-10, Volume: 178, Issue:2

    Topics: Acetyltransferases; Animals; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Drug Synergism; Enzyme Activation; Kinetics; Lymphocytes; Phorbol Esters; Phorbols; Phytohemagglutinins; Tetradecanoylphorbol Acetate

1984
Production of a cytotoxin from phorbol myristate acetate-treated human promyelocytes.
    Journal of the National Cancer Institute, 1984, Volume: 73, Issue:1

    Topics: Animals; Cell Line; Cytotoxins; Dactinomycin; Embryo, Mammalian; Fibroblasts; HeLa Cells; Humans; Kinetics; L Cells; Leukemia, Myeloid, Acute; Mice; Phorbols; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate

1984
Effect of RNA and protein synthesis inhibitors on the release of inflammatory mediators by macrophages responding to phorbol myristate acetate.
    Biochimica et biophysica acta, 1980, Dec-15, Volume: 633, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Cycloheximide; Dactinomycin; In Vitro Techniques; Macrophages; Male; Mice; Phorbols; Prostaglandins; Prostaglandins E; Prostaglandins F; Tetradecanoylphorbol Acetate; Zymosan

1980
Tumor promoter-mediated effects on Friend leukemia cells induced by actinomycin D: flow microfluorometry analysis and erythroid differentiation.
    Basic and applied histochemistry, 1982, Volume: 26, Issue:3

    Topics: Animals; Cell Cycle; Cell Differentiation; Cell Line; Dactinomycin; Flow Cytometry; Leukemia, Experimental; Mice; Phorbols; Tetradecanoylphorbol Acetate

1982
The induction of ornithine decarboxylase by tumor promoting phorbol ester analogues in Reuber H35 hepatoma cells.
    Life sciences, 1981, Nov-02, Volume: 29, Issue:18

    Topics: Animals; Carboxy-Lyases; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Polyamines; Rats; Tetradecanoylphorbol Acetate

1981
Induction of rat hepatic ornithine decarboxylase by the tumor promotors 12-O-tetradecanoylphorbol-13-acetate and phenobarbital in vivo; effect of retinyl-acetate.
    Carcinogenesis, 1981, Volume: 2, Issue:12

    Topics: Animals; Carboxy-Lyases; Cycloheximide; Dactinomycin; Diterpenes; Enzyme Induction; Female; Kinetics; Liver; Ornithine Decarboxylase; Phenobarbital; Phorbols; Rats; Retinyl Esters; Tetradecanoylphorbol Acetate; Vitamin A

1981