phorbols and choline
phorbols has been researched along with choline in 20 studies
Compound Research Comparison
| Studies (phorbols) | Trials (phorbols) | Recent Studies (post-2010) (phorbols) | Studies (choline) | Trials (choline) | Recent Studies (post-2010) (choline) |
|---|---|---|---|---|---|
| 2,217 | 0 | 72 | 19,628 | 608 | 4,345 |
Protein Interaction Comparison
| Protein | Taxonomy | phorbols (IC50) | choline (IC50) |
|---|---|---|---|
| Sodium- and chloride-dependent creatine transporter 1 | Rattus norvegicus (Norway rat) | 1.6 | |
| High affinity choline transporter 1 | Mus musculus (house mouse) | 1.6 |
Research
Studies (20)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Balmain, A; Hecker, E | 1 |
| Kensler, TW; Mueller, GC; Wertz, PW | 1 |
| Boutwell, RK; Kensler, TW; Mueller, GC; Verma, AK; Wertz, PW | 1 |
| Hecker, E; Kinzel, V; Kreibich, G; Süss, R | 1 |
| Mueller, GC; Wertz, PW | 2 |
| Daniel, LW; Waite, M; Wykle, RL | 1 |
| Paddon, HB; Pelech, SL; Vance, DE | 1 |
| Paddon, HB; Vance, DE | 1 |
| Greenebaum, E; Horowitz, AD; Nicolaides, M; Weinstein, IB; Woodward, K | 1 |
| Best, L; Hubinont, CJ; Malaisse, WJ; Sener, A | 1 |
| Kusunoki, M; Tanaka, C; Taniyama, K | 1 |
| Dawson, G; Golomb, HM; Lockney, MW | 1 |
| Mufson, RA; Okin, E; Weinstein, IB | 1 |
| Fisher, PB; Fujiki, H; Miranda, AF; Mufson, RA; Sugimura, T; Weinstein, IB; Weinstein, LS | 1 |
| Fjose, A; Kleppe, K; Lillehaug, JR; Pryme, IF | 1 |
| Froscio, M; Guy, GR; Murray, AW | 1 |
| End, D; Guroff, G; Tolson, N; Yu, MY | 1 |
| Guy, GR; Murray, AW | 1 |
| Estensen, RD; Plagemann, PG | 1 |
Other Studies
20 other study(ies) available for phorbols and choline
| Article | Year |
|---|---|
On the biochemical mechanism of tumorigenesis in mouse skin. VII. The effects of tumor promoters on 3H-choline and 3H-glycerol incorporation into mouse epidermal phosphatidylcholine in relation to their effects on 3H-thymidine incorporation into DNA.
Topics: Animals; Choline; DNA, Neoplasm; Female; Glycerol; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Phosphatidylcholines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1976 |
Inhibition of phorbol ester action in lymphocytes by 5,6-epoxy-beta-ionone.
Topics: Animals; B-Lymphocytes; Cattle; Choline; Dose-Response Relationship, Drug; Epoxy Compounds; Lymph Nodes; Norisoprenoids; Phorbols; Phospholipids; Terpenes; Tetradecanoylphorbol Acetate | 1978 |
5,6-epoxyretinoic acid opposes the effects of 12-O-tetradecanoylphorbol-13-acetate in bovine lymphocytes.
Topics: Animals; Biotransformation; Cattle; Choline; Epoxy Compounds; Lymphocytes; Membrane Lipids; Phorbols; Phospholipids; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin | 1979 |
Stimulation of choline incorporation in cell cultures by phorbol derivatives and its correlation with their irritant and tumor-promoting activity.
Topics: Animals; Cells, Cultured; Choline; Colchicine; Dose-Response Relationship, Drug; HeLa Cells; Humans; Mice; Phorbols; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone | 1979 |
Rapid stimulation of phospholipid metabolism in bovine lymphocytes by tumor-promoting phorbol esters.
Topics: Cells, Cultured; Choline; Cycloheximide; Cytochalasin B; Dactinomycin; Drug Interactions; Lectins; Lymphocyte Activation; Lymphocytes; Phorbol Esters; Phorbols; Phospholipids; Tetradecanoylphorbol Acetate; Tretinoin | 1978 |
A novel mechanism of diglyceride formation. 12-O-tetradecanoylphorbol-13-acetate stimulates the cyclic breakdown and resynthesis of phosphatidylcholine.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Choline; Diglycerides; Dogs; Glycerides; Kidney; Palmitic Acid; Palmitic Acids; Phorbols; Phosphates; Phosphatidylcholines; Phosphatidylethanolamines; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1986 |
Phorbol esters stimulate phosphatidylcholine biosynthesis by translocation of CTP:phosphocholine cytidylyltransferase from cytosol to microsomes.
Topics: Biological Transport; Choline; Choline-Phosphate Cytidylyltransferase; Cytosol; Digitonin; HeLa Cells; Humans; Kinetics; Microsomes; Nucleotidyltransferases; Phorbols; Tetradecanoylphorbol Acetate; Tritium | 1984 |
Tetradecanoyl-phorbol acetate stimulates phosphatidylcholine biosynthesis in HeLa cells by an increase in the rate of the reaction catalyzed by CTP:phosphocholine cytidylyltransferase.
Topics: Choline; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; HeLa Cells; Humans; Nucleotidyltransferases; Phorbol Esters; Phorbols; Phosphatidylcholines; Stimulation, Chemical | 1980 |
Inhibition of phorbol ester-receptor binding by a factor from human serum.
Topics: Animals; Arachidonic Acids; Blood; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Cell Membrane; Choline; Embryo, Mammalian; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Male; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phospholipids; Pregnancy; Protein Kinase C; Rats; Receptors, Cell Surface; Receptors, Drug; Sex Characteristics | 1982 |
Activation of protein kinase C by a tumor-promoting phorbol ester in pancreatic islets.
Topics: Animals; Calcium; Choline; Diglycerides; Enzyme Activation; Insulin; Insulin Secretion; Islets of Langerhans; Phorbols; Phosphatidylcholines; Phosphatidylinositols; Phosphorus Radioisotopes; Protein Kinase C; Protein Kinases; Rats; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1984 |
A phorbol ester and A23187 act synergistically to release acetylcholine from the guinea pig ileum.
Topics: Acetylcholine; Animals; Calcimycin; Calcium; Choline; Drug Synergism; Electric Stimulation; Female; Guinea Pigs; Ileum; Kinetics; Male; Phorbols; Tetradecanoylphorbol Acetate; Tritium | 1984 |
Phorbol ester tumor promoters specifically stimulate choline phospholipid metabolism in human leukemic cells.
Topics: Acetates; Acetic Acid; Caenorhabditis elegans Proteins; Carbon Radioisotopes; Carcinogens; Carrier Proteins; Cells, Cultured; Choline; Humans; Leukemia, Hairy Cell; Microscopy, Electron, Scanning; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylcholines; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tritium | 1984 |
Phorbol esters stimulate the rapid release of choline from prelabelled cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Choline; Inositol; Mice; Phorbol Esters; Phorbols; Phosphatidylcholines; Phospholipids; Time Factors | 1981 |
Effects of teleocidin and the phorbol ester tumor promoters on cell transformation, differentiation, and phospholipid metabolism.
Topics: Adenoviruses, Human; Alkaloids; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Choline; Humans; Lyngbya Toxins; Melanins; Melanoma; Mice; Muscles; Phorbols; Phospholipids; Rats; Tetradecanoylphorbol Acetate | 1982 |
The nuclear-associated endoplasmic reticulum is an early target for the action of the tumor promoter 12-O-tetradecanoyl phorbol-13-acetate in C3H/10T1/2 fibroblasts.
Topics: Animals; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; Choline; Endoplasmic Reticulum; Intracellular Membranes; Membrane Lipids; Mice; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Calmodulin inhibitors modify cell surface changes triggered by a tumor promoter.
Topics: Animals; Calcium-Binding Proteins; Calmodulin; Cell Line; Cell Membrane; Choline; Epidermal Growth Factor; Epidermis; HeLa Cells; Humans; Membrane Lipids; Mice; Phorbols; Phospholipids; Tetradecanoylphorbol Acetate; Trifluoperazine | 1981 |
Effects of 12-0-Tetradecanoylphorbol-13-acetate (TPA) on rat pheochromocytoma (PC12) cells: interactions with epidermal growth factor and nerve growth factor.
Topics: Animals; Cell Differentiation; Cell Line; Choline; Drug Interactions; Enzyme Induction; Epidermal Growth Factor; Nerve Growth Factors; Neurons; Ornithine Decarboxylase; Pheochromocytoma; Phorbols; Phosphates; Phosphorylation; Proteins; Rats; Tetradecanoylphorbol Acetate | 1982 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-accelerated phospholipid metabolism by 5,8,11,14-eicosatetraynoic acid.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Cattle; Choline; Epoprostenol; Fatty Acids, Unsaturated; Phorbols; Phospholipids; Prostaglandins; Tetradecanoylphorbol Acetate | 1980 |
Tumor promoter stimulation of phosphatidylcholine turnover in HeLa cells.
Topics: Choline; Diterpenes; Dose-Response Relationship, Drug; Enzyme Activation; HeLa Cells; Humans; Phorbol Esters; Phorbols; Phosphatidylcholines; Phospholipases; Phospholipids; Phosphorylcholine; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Lack of correlation between effects of tumor promoter TPA on plasminogen activator production, phosphatidyl choline synthesis, and hexose transport in mammalian cell culture systems.
Topics: Animals; Biological Transport, Active; Cell Line; Cells, Cultured; Choline; Cricetinae; Cricetulus; Female; HeLa Cells; Hexoses; Humans; Kidney; Leukemia, Experimental; Lymphocytes; Mice; Mice, Inbred BALB C; Ovary; Phorbols; Phosphatidylcholines; Plasminogen Activators; Rats; Tetradecanoylphorbol Acetate | 1980 |