Page last updated: 2024-09-04

phorbols and amiloride

phorbols has been researched along with amiloride in 14 studies

Compound Research Comparison

Studies
(phorbols)
Trials
(phorbols)
Recent Studies (post-2010)
(phorbols)
Studies
(amiloride)
Trials
(amiloride)
Recent Studies (post-2010) (amiloride)
2,2170727,584339788

Protein Interaction Comparison

ProteinTaxonomyphorbols (IC50)amiloride (IC50)
Urokinase-type plasminogen activatorHomo sapiens (human)4.7
Urokinase-type plasminogen activatorMus musculus (house mouse)2.3
Amine oxidase [flavin-containing] AHomo sapiens (human)3.909
Sodium/hydrogen exchanger 1Rattus norvegicus (Norway rat)1
Amiloride-sensitive sodium channel subunit alphaHomo sapiens (human)0.776
Sodium/hydrogen exchanger 2Oryctolagus cuniculus (rabbit)1
Acid-sensing ion channel 3Homo sapiens (human)4.4

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199011 (78.57)18.7374
1990's2 (14.29)18.2507
2000's1 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Paradiso, AM1
Elder, B; Furuya, W; Grinstein, S1
Hoshi, T; Shimada, T1
Besterman, JM; Cragoe, EJ; Cuatrecasas, P; LeVine, H; May, WS1
Cohen, S; Gelfand, EW; Goetz, JD; Grinstein, S; Rothstein, A1
Civan, MM; Mauro, T; O'Brien, TG; Rubenstein, D1
Frelin, C; Lazdunski, M; Vigne, P1
Cohen, S; Goetz, JD; Grinstein, S; Rothstein, A1
Czech, MP; Davis, RJ1
Dubyak, G; Scarpa, A; Wiener, E1
Cantley, LC; Rosoff, PM; Stein, LF1
Besterman, JM; Cuatrecasas, P1
Frindt, G; Palmer, LG; Windhager, EE1
DeSimone, JA; Lyall, V; Mahavadi, S; Melone, P; Mummalaneni, S; Murthy, KS; Phan, TH1

Other Studies

14 other study(ies) available for phorbols and amiloride

ArticleYear
Identification of Na(+)-H+ exchange in human normal and cystic fibrotic ciliated airway epithelium.
    The American journal of physiology, 1992, Volume: 262, Issue:6 Pt 1

    Topics: Adolescent; Adult; Amiloride; Carrier Proteins; Cells, Cultured; Cilia; Cystic Fibrosis; Epithelium; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Nasal Mucosa; Nasal Polyps; Phorbols; Potassium; Reference Values; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate

1992
Phorbol ester-induced changes of cytoplasmic pH in neutrophils: role of exocytosis in Na+-H+ exchange.
    The American journal of physiology, 1985, Volume: 248, Issue:3 Pt 1

    Topics: Amiloride; Animals; Cytochalasin B; Cytoplasmic Granules; Exocytosis; Hydrogen-Ion Concentration; Ion Channels; Neutrophils; Phorbols; Sodium; Swine; Tetradecanoylphorbol Acetate

1985
Na+-dependent elevation of the acidic cell surface pH (microclimate pH) of rat jejunal villus cells induced by cyclic nucleotides and phorbol ester: possible mediators of the regulation of the Na+/H+ antiporter.
    Biochimica et biophysica acta, 1988, Jan-22, Volume: 937, Issue:2

    Topics: Amiloride; Animals; Bucladesine; Calcimycin; Carrier Proteins; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprostone; Hydrogen-Ion Concentration; Jejunum; Male; Microvilli; Phorbol Esters; Phorbols; Prostaglandins E; Rats; Rats, Inbred Strains; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Theophylline

1988
Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange.
    The Journal of biological chemistry, 1985, Jan-25, Volume: 260, Issue:2

    Topics: Amiloride; Carrier Proteins; Cell Adhesion; Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Pyrazines; Receptors, Cell Surface; Receptors, Transferrin; Sodium-Hydrogen Exchangers

1985
Characterization of the activation of Na+/H+ exchange in lymphocytes by phorbol esters: change in cytoplasmic pH dependence of the antiport.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:5

    Topics: Amiloride; Animals; Calcium; Carrier Proteins; Hydrogen-Ion Concentration; Lymphocytes; Membrane Potentials; Phorbol Esters; Phorbols; Rats; Sodium; Sodium-Hydrogen Exchangers; Water-Electrolyte Balance

1985
Effects of tumor promoters on sodium ion transport across frog skin.
    The American journal of physiology, 1985, Volume: 248, Issue:5 Pt 1

    Topics: Amiloride; Animals; Biological Transport, Active; Carcinogens; Cyclic AMP; Indomethacin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Rana pipiens; Skin; Sodium; Tetradecanoylphorbol Acetate

1985
The Na+/H+ antiport is activated by serum and phorbol esters in proliferating myoblasts but not in differentiated myotubes. Properties of the activation process.
    The Journal of biological chemistry, 1985, Jul-05, Volume: 260, Issue:13

    Topics: Amiloride; Animals; Blood; Carrier Proteins; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Epidermal Growth Factor; Hydrogen-Ion Concentration; Kinetics; Muscle Development; Phorbol Esters; Phorbols; Rats; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate

1985
Osmotic and phorbol ester-induced activation of Na+/H+ exchange: possible role of protein phosphorylation in lymphocyte volume regulation.
    The Journal of cell biology, 1985, Volume: 101, Issue:1

    Topics: Adenosine Triphosphate; Amiloride; Animals; Calcium; Carrier Proteins; Cytoplasm; Diglycerides; Enzyme Activation; Lymphocytes; Male; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; Sodium-Hydrogen Exchangers; Trifluoperazine; Water-Electrolyte Balance

1985
Inhibition of the apparent affinity of the epidermal growth factor receptor caused by phorbol diesters correlates with phosphorylation of threonine-654 but not other sites on the receptor.
    The Biochemical journal, 1986, Jan-15, Volume: 233, Issue:2

    Topics: Amiloride; Amino Acids; Binding Sites; Carcinoma, Squamous Cell; Cell Line; ErbB Receptors; Humans; Phorbols; Phosphopeptides; Phosphorylation; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Threonine

1986
Na+/H+ exchange in Ehrlich ascites tumor cells. Regulation by extracellular ATP and 12-O-tetradecanoylphorbol 13-acetate.
    The Journal of biological chemistry, 1986, Apr-05, Volume: 261, Issue:10

    Topics: Adenosine Triphosphate; Amiloride; Animals; Calcium; Carcinoma, Ehrlich Tumor; Carrier Proteins; Hydrogen-Ion Concentration; Kinetics; Mice; Phorbols; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate

1986
Phorbol esters induce differentiation in a pre-B-lymphocyte cell line by enhancing Na+/H+ exchange.
    The Journal of biological chemistry, 1984, Jun-10, Volume: 259, Issue:11

    Topics: Adenosine Triphosphatases; Amiloride; Animals; B-Lymphocytes; Carrier Proteins; Cation Transport Proteins; Cell Differentiation; Hydrogen-Ion Concentration; Lipopolysaccharides; Mice; Phorbols; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Time Factors

1984
Phorbol esters rapidly stimulate amiloride-sensitive Na+/H+ exchange in a human leukemic cell line.
    The Journal of cell biology, 1984, Volume: 99, Issue:1 Pt 1

    Topics: Amiloride; Carrier Proteins; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pyrazines; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate

1984
Feedback regulation of Na channels in rat CCT. IV. Mediation by activation of protein kinase C.
    The American journal of physiology, 1996, Volume: 270, Issue:2 Pt 2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Feedback; Female; Kidney Tubules, Collecting; Male; Ouabain; Patch-Clamp Techniques; Phorbols; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Staurosporine; Tetradecanoylphorbol Acetate; Up-Regulation

1996
Regulation of the benzamil-insensitive salt taste receptor by intracellular Ca2+, protein kinase C, and calcineurin.
    Journal of neurophysiology, 2009, Volume: 102, Issue:3

    Topics: Amiloride; Animals; Benzamides; Calcineurin; Calcium; Chelating Agents; Chorda Tympani Nerve; Diterpenes; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Extracellular Fluid; Female; Gene Expression Regulation; Mice; Mice, Inbred C57BL; Mice, Knockout; Phorbols; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium Chloride; Taste; Taste Buds; Taste Threshold; TRPV Cation Channels

2009