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phorbol 12,13-dibutyrate and ucn 1028 c

phorbol 12,13-dibutyrate has been researched along with ucn 1028 c in 60 studies

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's31 (51.67)18.2507
2000's24 (40.00)29.6817
2010's5 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruns, RF; Heath, WF; Howbert, JJ; Kobayashi, E; Merriman, RL; Miller, FD; Nakano, H; Takahashi, I; Tamaoki, T1
Areces, LB; Blumberg, PM; Kazanietz, MG1
Mühl, H; Pfeilschifter, J1
Cano, C; Malik, KU; Slavik, KJ1
Budworth, J; Gescher, A1
Argent, BE; Gray, MA; McAlroy, HL; Winpenny, JP1
Blumberg, PM; Bruns, JD; Kazanietz, MG; Lewin, NE1
Giaid, A; Harrison, DG; Kurz, S; Münzel, T; Stewart, DJ1
Kopp, UC; Smith, LA1
Daniel, EE; Kwan, CY; Shimamoto, H; Shimamoto, Y1
Didion, SP; Mayhan, WG1
Burt, RP; Chapple, CR; Marshall, I1
Cohen, ML; Cox, DA1
Kan, H; Malik, KU; Ruan, Y1
Kamei, J; Mizoguchi, H; Narita, M; Ohsawa, M; Tseng, LF1
Nash, MS; Osborne, NN; Wood, JP1
Goodyer, CG; Oh, LY; Olivier, A; Yong, VW1
Fung, H; Heintz, NH; Jaken, S; Janssen, YM; Marsh, JP; Mossman, BT; Quinlan, TR; Taatjes, DJ; Timblin, CR; Vacek, P1
Keiser, HR; Oriji, GK1
Bun, T; Kawamata, T; Peterson, JW; Zervas, NT1
Hano, T; Kimura, K; Nishio, I; Sasajima, H; Shima, H; Toyoda, Y; Yoshikawa, A1
Dent, G; Leff, AR; Magnussen, H; Muñoz, NM; Rabe, KF; Rühlmann, E; Zhu, X1
Kamei, J; Ohsawa, M3
Breuiller-Fouché, M; Ferré, F; Fournier, T; Héluy, V; Tertrin-Clary, C1
Fukao, M; Hattori, Y; Kanno, M; Kitabatake, A; Sakuma, I; Sato, A1
Hattori, Y; Kanno, M; Kitabatake, A; Kohya, T; Moriishi, K; Oguma, K; Sasaki, M; Tomita, F1
Nicolás, JM; Renard-Rooney, DC; Thomas, AP1
Dessauer, CW; Hume, JR; Keef, KD; Zhong, J1
Inoue, T; Koono, M; Nabeshima, K; Shimao, Y1
Hitosugi, H; Kamei, J; Ohsawa, M1
Sanders, JL; Stern, PH1
Chen, C; Clarke, IJ; Loneragan, K; Roh, SG; Ruan, M; Xu, R1
Brandon, NJ; Brown, DA; Delmas, P; Kittler, JT; McDonald, BJ; Moss, SJ; Sieghart, W; Smart, TG1
Björklund, S; Dugué, B; Titievsky, A; Törnquist, K; Tuominen, RK; Vainio, PJ1
Cantwell, AM; Long, W; Longo, LD; Miguel, C; Nanyonga, AT; Saito, T; Windemuth, RS; Zhang, L; Zhao, Y1
Brown, PD; Kajita, H; Whitwell, C1
Breuiller-Fouché, M; Cabrol, D; Eude, I; Ferré, F; Paris, B1
Coats, P; Hillier, C; Johnston, F; MacDonald, J; McMurray, JJ1
Jun, JY; Koh, SD; Kong, ID; Perrino, BA; Sanders, KM; Wang, XY; Ward, SM1
Deth, RC; Sharma, A; Waly, M1
Cho, H; Earm, YE; Ho, WK; Youm, JB1
Iguchi, E; Kamei, J; Morita, K; Sasaki, M; Tanaka, S; Zushida, K1
Cavallero, S; Damiano, P; de la Riva, I; Fernández, B; Mayer, M; Puyó, AM; Rosón, MI1
Callaghan, B; Keef, KD; Koh, SD1
Burnstock, G; Smith, NC1
Chiba, Y; Hirano, T; Misawa, M; Sakai, H; Takeyama, H1
Khisti, RT; Kumar, S; Morrow, AL1
Abe, K; Hoshi, K; Ishikawa, M; Matsushita, Y; Quock, RM; Taguchi, K; Utsunomiya, I1
Bildin, VN; Mergler, S; Reinach, PS; Wang, Z; Wen, Q; Yang, H; Zhang, F1
Furness, JB; Poole, DP1
Balfagón, G; Blanco-Rivero, J; Ferrer, M; Sagredo, A1
Kim, YK1
Abebe, W; Mozaffari, MS1
Heaps, CL; Parker, JL; Robles, JC; Sturek, M1
Maxwell, PJ; Rattan, S; Singh, J1
Bosco, AA; Mattos, RT; Nogueira-Machado, JA1
Paisansathan, C; Pelligrino, DA; Vetri, F; Xu, H1
Rattan, S; Singh, J1

Other Studies

60 other study(ies) available for phorbol 12,13-dibutyrate and ucn 1028 c

ArticleYear
Inhibition of protein kinase C by calphostin C is light-dependent.
    Biochemical and biophysical research communications, 1991, Apr-15, Volume: 176, Issue:1

    Topics: Animals; Brain; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Darkness; Down-Regulation; ErbB Receptors; Humans; Kinetics; Light; Naphthalenes; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Protein Kinase C; Rats; Rats, Inbred Strains

1991
Close similarity of baculovirus-expressed n-chimaerin and protein kinase C alpha as phorbol ester receptors.
    The Journal of biological chemistry, 1994, Jul-29, Volume: 269, Issue:30

    Topics: Amino Acid Sequence; Animals; Baculoviridae; Base Sequence; Caenorhabditis elegans Proteins; Carrier Proteins; Cells, Cultured; Chimerin 1; Isoenzymes; Molecular Sequence Data; Moths; Naphthalenes; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Phosphatidylserines; Phospholipids; Polycyclic Compounds; Protein Kinase C; Protein Kinase C-alpha; Receptors, Drug; Sphingosine

1994
Possible role of protein kinase C-epsilon isoenzyme in inhibition of interleukin 1 beta induction of nitric oxide synthase in rat renal mesangial cells.
    The Biochemical journal, 1994, Oct-15, Volume: 303 ( Pt 2)

    Topics: Amino Acid Oxidoreductases; Animals; Blotting, Northern; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Induction; Glomerular Mesangium; Interleukin-1; Isoenzymes; NADH Dehydrogenase; Naphthalenes; Nitric Oxide Synthase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Polycyclic Compounds; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate

1994
Loss of adenosine-induced negative inotropic effect in hyperexcited rabbit hearts: relationship to PKC.
    The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 2

    Topics: Acetylcholine; Adenosine; Angiotensin II; Animals; Behavior, Animal; Biphenyl Compounds; Blood Pressure; Depression, Chemical; Enzyme Activation; Heart Rate; Imidazoles; In Vitro Techniques; Losartan; Male; Myocardial Contraction; Naphthalenes; Norepinephrine; Perfusion; Phentolamine; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Propranolol; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Tetrazoles

1995
Differential inhibition of cytosolic and membrane-derived protein kinase C activity by staurosporine and other kinase inhibitors.
    FEBS letters, 1995, Apr-03, Volume: 362, Issue:2

    Topics: Alkaloids; Breast Neoplasms; Cell Membrane; Cytosol; Humans; Immunoblotting; Indoles; Naphthalenes; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tumor Cells, Cultured

1995
Protein kinase C regulates the magnitude and stability of CFTR currents in pancreatic duct cells.
    The American journal of physiology, 1995, Volume: 268, Issue:4 Pt 1

    Topics: Animals; Cells, Cultured; Chloride Channels; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Membrane Proteins; Naphthalenes; Pancreatic Ducts; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Protein Kinase C; Rats

1995
Characterization of the cysteine-rich region of the Caenorhabditis elegans protein Unc-13 as a high affinity phorbol ester receptor. Analysis of ligand-binding interactions, lipid cofactor requirements, and inhibitor sensitivity.
    The Journal of biological chemistry, 1995, May-05, Volume: 270, Issue:18

    Topics: Amino Acid Sequence; Animals; Base Sequence; Bryostatins; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Cysteine; DNA Primers; Helminth Proteins; Lactones; Ligands; Macrolides; Molecular Sequence Data; Naphthalenes; Phorbol 12,13-Dibutyrate; Phospholipids; Polycyclic Compounds; Protein Kinase C; Receptors, Drug; Recombinant Proteins

1995
Evidence for a role of endothelin 1 and protein kinase C in nitroglycerin tolerance.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, May-23, Volume: 92, Issue:11

    Topics: Alkaloids; Angiotensin II; Animals; Aorta, Thoracic; Drug Tolerance; Endothelins; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Nitroglycerin; Phenylephrine; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Potassium Chloride; Protein Kinase C; Rabbits; Serotonin; Staurosporine; Vasoconstriction

1995
A role for protein kinase C in bradykinin-mediated activation of renal pelvic sensory receptors.
    The American journal of physiology, 1995, Volume: 269, Issue:2 Pt 2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bradykinin; Enzyme Activation; Isoquinolines; Kidney Pelvis; Male; Naphthalenes; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Staurosporine

1995
Differential effects of putative protein kinase C inhibitors on contraction of rat aortic smooth muscle.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Aorta; Dose-Response Relationship, Drug; Isoquinolines; Male; Muscle, Smooth, Vascular; Naphthalenes; Phenylephrine; Phorbol 12,13-Dibutyrate; Piperazines; Polycyclic Compounds; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Vasoconstriction

1993
Activation of protein kinase C does not participate in disruption of the blood-brain barrier to albumin during acute hypertension.
    Brain research, 1995, Oct-23, Volume: 696, Issue:1-2

    Topics: Acute Disease; Animals; Blood Pressure; Blood-Brain Barrier; Capillary Permeability; Enzyme Activation; Enzyme Inhibitors; Hypertension; Male; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sphingosine

1995
The role of diacylglycerol and activation of protein kinase C in alpha 1A-adrenoceptor-mediated contraction to noradrenaline of rat isolated epididymal vas deferens.
    British journal of pharmacology, 1996, Volume: 117, Issue:1

    Topics: Animals; Calcium; Carcinogens; Cyclohexanones; Diglycerides; Lipoprotein Lipase; Male; Naphthalenes; Norepinephrine; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Staurosporine; Thiazoles; Vas Deferens

1996
Lysophosphatidylcholine stimulates phospholipase D in human coronary endothelial cells: role of PKC.
    The American journal of physiology, 1996, Volume: 271, Issue:4 Pt 2

    Topics: Alkaloids; Benzophenanthridines; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Humans; Indoles; Lysophosphatidylcholines; Maleimides; Naphthalenes; Phenanthridines; Phorbol 12,13-Dibutyrate; Phospholipase D; Protein Kinase C

1996
Involvement of mitogen-activated protein kinase and translocation of cytosolic phospholipase A2 to the nuclear envelope in acetylcholine-induced prostacyclin synthesis in rabbit coronary endothelial cells.
    Molecular pharmacology, 1996, Volume: 50, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Amino Acid Sequence; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Cells, Cultured; Coronary Vessels; Cytosol; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Molecular Sequence Data; Naphthalenes; Nitriles; Nitrophenols; Nuclear Envelope; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Phosphorylation; Rabbits; Tetradecanoylphorbol Acetate; Tyrphostins

1996
Pretreatment with protein kinase C activator phorbol 12,13-dibutyrate attenuates the antinociception induced by mu- but not epsilon-opioid receptor agonist in the mouse.
    Neuroscience, 1997, Volume: 76, Issue:1

    Topics: Analgesics; Animals; beta-Endorphin; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Activation; Enzyme Inhibitors; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naphthalenes; Nociceptors; Pain Measurement; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Opioid; Receptors, Opioid, mu; Time Factors

1997
Protein kinase C activation by serotonin potentiates agonist-induced stimulation of cAMP production in cultured rat retinal pigment epithelial cells.
    Experimental eye research, 1997, Volume: 64, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Isoproterenol; Naphthalenes; Phorbol 12,13-Dibutyrate; Pigment Epithelium of Eye; Protein Kinase C; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Staurosporine

1997
The promoting effects of bFGF and astrocyte extracellular matrix on process outgrowth by adult human oligodendrocytes are mediated by protein kinase C.
    Brain research, 1997, May-23, Volume: 757, Issue:2

    Topics: Astrocytes; Cells, Cultured; Enzyme Inhibitors; Extracellular Matrix; Fibroblast Growth Factor 2; Humans; Naphthalenes; Oligodendroglia; Phorbol 12,13-Dibutyrate; Protein Kinase C; Staurosporine

1997
Inhibition of protein kinase C prevents asbestos-induced c-fos and c-jun proto-oncogene expression in mesothelial cells.
    Cancer research, 1997, Aug-01, Volume: 57, Issue:15

    Topics: Animals; Asbestos; Benzoquinones; Epithelium; Gene Expression; Isoenzymes; Lactams, Macrocyclic; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Quinones; Rats; Rats, Inbred F344; Rifabutin; RNA, Messenger; Time Factors

1997
Protein kinase C mediates angiotensin II-induced contractions and the release of endothelin and prostacyclin in rat aortic rings.
    Prostaglandins, leukotrienes, and essential fatty acids, 1997, Volume: 57, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Epoprostenol; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Osmolar Concentration; Peptides, Cyclic; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Staurosporine; Vasoconstrictor Agents

1997
Augmentation of both hemolysate-induced contraction and activation of protein kinase C by submaximum activation in canine cerebral arteries in vitro.
    Journal of neurosurgery, 1997, Volume: 87, Issue:6

    Topics: Animals; Cell Membrane; Cerebral Arteries; Chronic Disease; Cytosol; Dogs; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Hemolysis; Ischemic Attack, Transient; Membrane Potentials; Muscle, Smooth, Vascular; Naphthalenes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Potassium; Protein Binding; Protein Kinase C; Stress, Mechanical; Subarachnoid Hemorrhage; Vasoconstriction; Vasoconstrictor Agents

1997
Increased Ca2+ sensitivity of contractile elements via protein kinase C in alpha-toxin permeabilized SMA from young spontaneously hypertensive rats.
    Cardiovascular research, 1997, Volume: 36, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analysis of Variance; Animals; Calcium; Enzyme Inhibitors; In Vitro Techniques; Male; Mesenteric Artery, Superior; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Staphylococcus aureus; Type C Phospholipases

1997
Protein kinase C inhibition enhances platelet-activating factor-induced eicosanoid production in human eosinophils.
    American journal of respiratory cell and molecular biology, 1998, Volume: 18, Issue:1

    Topics: Arachidonic Acid; Calcium; Catalase; Eicosanoids; Enzyme Inhibitors; Eosinophils; Female; Humans; Indoles; Leukotriene C4; Male; Maleimides; Naphthalenes; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2

1998
Possible involvement of protein kinase C in the attenuation of [D-Ala2, NMePhe4, Gly-ol5]enkephalin-induced antinociception in diabetic mice.
    European journal of pharmacology, 1997, Nov-19, Volume: 339, Issue:1

    Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Inhibitors; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naphthalenes; Nociceptors; Phorbol 12,13-Dibutyrate; Protein Kinase C; Reference Values

1997
Role of protein kinase C in endothelin-1-induced contraction of human myometrium.
    Biology of reproduction, 1998, Volume: 59, Issue:1

    Topics: Adult; Cytosol; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Isoenzymes; Middle Aged; Myometrium; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Uterine Contraction

1998
A role of myofilament Ca2+ sensitivity in enhanced vascular reactivity in cardiomyopathic hamsters.
    European journal of pharmacology, 1998, Jul-24, Volume: 353, Issue:2-3

    Topics: Actin Cytoskeleton; Angiotensin II; Animals; Aorta; Calcium; Calcium Channel Blockers; Cardiomyopathies; Cricetinae; Indoles; Male; Mesocricetus; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Nifedipine; Phenylephrine; Phorbol 12,13-Dibutyrate; Potassium; Ryanodine; Staurosporine; Vasoconstrictor Agents

1998
Tyrosine phosphorylation as a convergent pathway of heterotrimeric G protein- and rho protein-mediated Ca2+ sensitization of smooth muscle of rabbit mesenteric artery.
    British journal of pharmacology, 1998, Volume: 125, Issue:8

    Topics: Adenosine Diphosphate; ADP Ribose Transferases; Animals; Botulinum Toxins; Calcium; Carcinogens; Dimerization; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phenylephrine; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; rho GTP-Binding Proteins; Ribose; Staurosporine; Tyrosine; Tyrphostins; Vasoconstrictor Agents

1998
Tonic regulation of excitation-contraction coupling by basal protein kinase C activity in isolated cardiac myocytes.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:12

    Topics: Animals; Caffeine; Calcium-Transporting ATPases; Contractile Proteins; Enzyme Inhibitors; Heart; In Vitro Techniques; Kinetics; Magnesium; Male; Microscopy, Fluorescence; Myocardial Contraction; Myocardium; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sarcolemma; Sarcoplasmic Reticulum; Staurosporine; Time Factors

1998
Regulation of L-type Ca2+ channels in rabbit portal vein by G protein alphas and betagamma subunits.
    The Journal of physiology, 1999, May-15, Volume: 517 ( Pt 1)

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Proteins; In Vitro Techniques; Indoles; Male; Maleimides; Models, Biological; Muscle, Smooth, Vascular; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Portal Vein; Protein Conformation; Protein Kinase C; Pyrroles; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thionucleotides

1999
Modification of the expression of naloxone-precipitated withdrawal signs in morphine-dependent mice by diabetes: possible involvement of protein kinase C.
    Japanese journal of pharmacology, 1999, Volume: 79, Issue:3

    Topics: Animals; Behavior, Animal; Carbazoles; Carcinogens; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Frontal Lobe; Indoles; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Naloxone; Naphthalenes; Narcotic Antagonists; Narcotics; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrroles; Substance Withdrawal Syndrome

1999
Possible involvement of spinal protein kinase C in thermal allodynia and hyperalgesia in diabetic mice.
    European journal of pharmacology, 1999, May-21, Volume: 372, Issue:3

    Topics: Analysis of Variance; Animals; Capsaicin; Carbazoles; Carcinogens; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus; Enzyme Inhibitors; Hot Temperature; Hyperalgesia; Indoles; Male; Mice; Mice, Inbred ICR; Naphthalenes; Pain; Pain Measurement; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrroles; Spinal Cord

1999
TPA-enhanced motility and invasion in a highly metastatic variant (L-10) of human rectal adenocarcinoma cell line RCM-1: selective role of PKC-alpha and its inhibition by a combination of PDBu-induced PKC downregulation and antisense oligonucleotides trea
    Clinical & experimental metastasis, 1999, Volume: 17, Issue:4

    Topics: Adenocarcinoma; Base Sequence; Carbazoles; Down-Regulation; Humans; Indoles; Isoenzymes; Naphthalenes; Neoplasm Invasiveness; Neoplasm Metastasis; Oligonucleotides, Antisense; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Protein Kinase C-alpha; Rectal Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1999
Effect of diabetes on bradykinin-induced thermal hyperalgesia in mice.
    European journal of pharmacology, 2000, Feb-25, Volume: 390, Issue:1-2

    Topics: Animals; Bradykinin; Diabetes Mellitus, Experimental; Enzyme Activators; Enzyme Inhibitors; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Reaction Time

2000
Protein kinase C involvement in interleukin-6 production by parathyroid hormone and tumor necrosis factor-alpha in UMR-106 osteoblastic cells.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2000, Volume: 15, Issue:5

    Topics: Animals; Cell Line; Cyclic AMP; Down-Regulation; Interleukin-6; Naphthalenes; Osteoblasts; Parathyroid Hormone; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Tumor Necrosis Factor-alpha

2000
Diverse intracellular signalling systems used by growth hormone-releasing hormone in regulating voltage-gated Ca2+ or K channels in pituitary somatotropes.
    Immunology and cell biology, 2000, Volume: 78, Issue:4

    Topics: Alkaloids; Animals; Benzophenanthridines; Calcium Channels; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Growth Hormone-Releasing Hormone; Humans; Isoquinolines; Naphthalenes; Patch-Clamp Techniques; Phenanthridines; Phorbol 12,13-Dibutyrate; Pituitary Gland; Potassium Channels; Protein Kinase C; Sheep; Signal Transduction; Sulfonamides

2000
GABAA receptor phosphorylation and functional modulation in cortical neurons by a protein kinase C-dependent pathway.
    The Journal of biological chemistry, 2000, Dec-08, Volume: 275, Issue:49

    Topics: Animals; Cell Line; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Humans; Kinetics; Naphthalenes; Neurons; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinases; Protein Subunits; Pyramidal Cells; Rats; Receptors, GABA-A; Recombinant Proteins; Serine; Signal Transduction; Transfection

2000
Hydrogen peroxide attenuates store-operated calcium entry and enhances calcium extrusion in thyroid FRTL-5 cells.
    The Biochemical journal, 2000, Oct-01, Volume: 351, Issue:Pt 1

    Topics: Adenosine Triphosphate; Animals; Barium; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cell Line; Down-Regulation; Enzyme Activation; Hydrogen Peroxide; Isoenzymes; Manganese; Membrane Potentials; Mercaptoethanol; Naphthalenes; Oxidation-Reduction; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Transport; Rats; Sodium; Staurosporine; Thapsigargin; Thyroid Gland

2000
Dual role of PKC in modulating pharmacomechanical coupling in fetal and adult cerebral arteries.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:4

    Topics: Animals; Cell Membrane; Cerebral Arteries; Enzyme Inhibitors; Feedback; Fetus; Indoles; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Lactams; Naphthalenes; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Sheep; Signal Transduction; Staurosporine; Vasoconstriction

2000
Properties of the inward-rectifying Cl- channel in rat choroid plexus: regulation by intracellular messengers and inhibition by divalent cations.
    Pflugers Archiv : European journal of physiology, 2000, Volume: 440, Issue:6

    Topics: Adenosine Triphosphate; Animals; Cadmium; Cations, Divalent; Chloride Channels; Choroid Plexus; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Electric Conductivity; Electrodes; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Solutions; Tetradecanoylphorbol Acetate; Zinc

2000
Selective protein kinase C isoforms are involved in endothelin-1-induced human uterine contraction at the end of pregnancy.
    Biology of reproduction, 2000, Volume: 63, Issue:5

    Topics: Blotting, Western; Carbazoles; Chelating Agents; Cytosol; Down-Regulation; Egtazic Acid; Endothelin-1; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Indoles; Isoenzymes; Myometrium; Naphthalenes; Phorbol 12,13-Dibutyrate; Pregnancy; Protein Kinase C; Receptors for Activated C Kinase; Receptors, Cell Surface; Uterine Contraction

2000
Signalling mechanisms underlying the myogenic response in human subcutaneous resistance arteries.
    Cardiovascular research, 2001, Volume: 49, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aged; Analysis of Variance; Arteries; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cyclohexanones; Enzyme Inhibitors; Estrenes; Female; Humans; In Vitro Techniques; Indoles; Lipoprotein Lipase; Male; Middle Aged; Muscle, Smooth, Vascular; Naphthalenes; Nifedipine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrrolidinones; Ryanodine; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Type C Phospholipases; Vascular Resistance

2001
Regulation of ATP-sensitive K(+) channels by protein kinase C in murine colonic myocytes.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:3

    Topics: Acetylcholine; Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Colon; Enzyme Activation; Enzyme Inhibitors; Female; Glyburide; In Vitro Techniques; Isoenzymes; Kinetics; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Muscle, Smooth; Naphthalenes; Patch-Clamp Techniques; Phenanthridines; Phorbol 12,13-Dibutyrate; Pinacidil; Potassium Channels; Protein Kinase C; Protein Kinase C-epsilon

2001
Protein kinase C regulates dopamine D4 receptor-mediated phospholipid methylation.
    European journal of pharmacology, 2001, Sep-14, Volume: 427, Issue:2

    Topics: Alkaloids; Benzophenanthridines; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Methylation; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phenanthridines; Phorbol 12,13-Dibutyrate; Phospholipids; Protein Kinase C; Receptors, Dopamine D2; Receptors, Dopamine D4; Thionucleotides; Tumor Cells, Cultured

2001
Inhibition of acetylcholine-activated K(+) current by chelerythrine and bisindolylmaleimide I in atrial myocytes from mice.
    European journal of pharmacology, 2001, Jul-27, Volume: 424, Issue:3

    Topics: Acetylcholine; Alkaloids; Animals; Atrial Function; Benzophenanthridines; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Heart Atria; Indoles; Maleimides; Membrane Potentials; Mice; Naphthalenes; Patch-Clamp Techniques; Phenanthridines; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C

2001
Modification of the fenvalerate-induced nociceptive response in mice by diabetes.
    Brain research, 2002, Sep-06, Volume: 948, Issue:1-2

    Topics: Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enzyme Activators; Enzyme Inhibitors; Hindlimb; Injections, Spinal; Male; Mexiletine; Mice; Mice, Inbred ICR; Naphthalenes; Nitriles; Pain Measurement; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrethrins; Sodium Channels; Streptozocin

2002
Impaired response to insulin associated with protein kinase C in chronic fructose-induced hypertension.
    Blood pressure, 2002, Volume: 11, Issue:6

    Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Enzyme Activators; Enzyme Inhibitors; Fructose; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley

2002
Muscarinic M2 receptor stimulation of Cav1.2b requires phosphatidylinositol 3-kinase, protein kinase C, and c-Src.
    Circulation research, 2004, Mar-19, Volume: 94, Issue:5

    Topics: Acetylcholine; Animals; Barium; Calcium Channels, L-Type; Carbazoles; Cells, Cultured; Chromones; Class Ib Phosphatidylinositol 3-Kinase; Diamines; Enzyme Inhibitors; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Indoles; Ion Channel Gating; Ion Transport; Isoenzymes; Male; Morpholines; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Portal Vein; Protein Kinase C; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Rabbits; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Signal Transduction

2004
Mechanisms underlying postjunctional synergism between responses of the vas deferens to noradrenaline and ATP.
    European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Cantharidin; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Histamine; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; Muscle, Smooth; Naphthalenes; Norepinephrine; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Prazosin; Protein Kinase C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; rho-Associated Kinases; Vas Deferens

2004
Acetylcholine-induced phosphorylation of CPI-17 in rat bronchial smooth muscle: the roles of Rho-kinase and protein kinase C.
    Canadian journal of physiology and pharmacology, 2005, Volume: 83, Issue:4

    Topics: Acetylcholine; Animals; Bronchi; Enzyme Inhibitors; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle Proteins; Muscle, Smooth; Myosin Light Chains; Naphthalenes; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; rho-Associated Kinases; Type C Phospholipases; Vasodilator Agents

2005
Regulation of native GABAA receptors by PKC and protein phosphatase activity.
    Psychopharmacology, 2005, Volume: 183, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; GABA Agonists; gamma-Aminobutyric Acid; Isotopes; Male; Microcystins; Muscimol; Naphthalenes; Peptides, Cyclic; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

2005
Involvement of brain protein kinase C in nitrous oxide-induced antinociception in mice.
    Neuroscience, 2006, Jun-19, Volume: 140, Issue:1

    Topics: Analgesics; Analysis of Variance; Animals; Blotting, Western; Brain; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Male; Mice; Mice, Inbred C57BL; Naphthalenes; Nitrous Oxide; Nociceptors; Pain Measurement; Phorbol 12,13-Dibutyrate; Protein Kinase C

2006
PKC isoform-specific enhancement of capacitative calcium entry in human corneal epithelial cells.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:9

    Topics: Blotting, Western; Calcium; Calcium Channels; Cell Line; Epidermal Growth Factor; Epithelium, Corneal; Fura-2; Gene Deletion; Humans; Isoenzymes; Microscopy, Fluorescence; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-delta; RNA, Small Interfering; Transfection

2006
PKC delta-isoform translocation and enhancement of tonic contractions of gastrointestinal smooth muscle.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:3

    Topics: Animals; Carbachol; Cytoplasm; Cytoskeleton; Diacylglycerol Kinase; Diterpenes; Female; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Isoenzymes; Male; Maleimides; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Transport; Scopolamine; Subcellular Fractions

2007
Protein kinase C activation increases endothelial nitric oxide release in mesenteric arteries from orchidectomized rats.
    The Journal of endocrinology, 2007, Volume: 192, Issue:1

    Topics: Acetylcholine; Animals; Blotting, Western; Carbazoles; Dose-Response Relationship, Drug; Enzyme Activation; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Orchiectomy; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Superoxides; Thromboxane A2; Vasodilator Agents

2007
TGF-beta1 induction of p21WAF1/cip1 requires smad-independent protein kinase C signaling pathway.
    Archives of pharmacal research, 2007, Volume: 30, Issue:6

    Topics: Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Dimethyl Sulfoxide; Genes, Reporter; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Immunoblotting; Immunohistochemistry; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1; Tubulin

2007
Vascular reactivity changes in glucose-intolerant rat.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:5

    Topics: Acetylcholine; Animals; Animals, Newborn; Aorta; Blood Glucose; Body Weight; Calcium; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Egtazic Acid; Glucose Intolerance; Glucose Tolerance Test; In Vitro Techniques; Male; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitroprusside; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Inbred WKY; Serotonin; Vasoconstriction; Vasodilation

2007
Ca2+ sensitization and PKC contribute to exercise training-enhanced contractility in porcine collateral-dependent coronary arteries.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Calcium; Collateral Circulation; Coronary Vessels; Endothelin-1; Enzyme Inhibitors; Female; Muscle Contraction; Naphthalenes; Phorbol 12,13-Dibutyrate; Physical Conditioning, Animal; Protein Kinase C; Pyridines; rho-Associated Kinases; Swine; Vasodilator Agents

2011
Immunocytochemical evidence for PDBu-induced activation of RhoA/ROCK in human internal anal sphincter smooth muscle cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 301, Issue:2

    Topics: ADP Ribose Transferases; Amides; Anal Canal; Botulinum Toxins; Cells, Cultured; Fluorescent Antibody Technique; Humans; Muscle Contraction; Myocytes, Smooth Muscle; Myosin-Light-Chain Phosphatase; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C-alpha; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction

2011
Rosiglitazone, a PPAR-γ agonist, inhibits VEGF secretion by peripheral blood mononuclear cells and ROS production by human leukocytes.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2012, Volume: 61, Issue:1

    Topics: Adult; Humans; Hypoglycemic Agents; Leukocytes; Leukocytes, Mononuclear; Luminescence; Middle Aged; Naphthalenes; Phorbol 12,13-Dibutyrate; PPAR gamma; Protein Kinase C; Reactive Oxygen Species; Rosiglitazone; Thiazolidinediones; Vascular Endothelial Growth Factor A

2012
Impairment of neurovascular coupling in type 1 diabetes mellitus in rats is linked to PKC modulation of BK(Ca) and Kir channels.
    American journal of physiology. Heart and circulatory physiology, 2012, Mar-15, Volume: 302, Issue:6

    Topics: Animals; Arterioles; Benzimidazoles; Cerebrovascular Circulation; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Electric Stimulation; Enzyme Activation; Enzyme Activators; Female; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Naphthalenes; Phorbol 12,13-Dibutyrate; Phosphorylation; Pia Mater; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Time Factors; Vasodilation

2012
Role of PKC and RhoA/ROCK pathways in the spontaneous phasic activity in the rectal smooth muscle.
    American journal of physiology. Gastrointestinal and liver physiology, 2013, Apr-15, Volume: 304, Issue:8

    Topics: Amides; Animals; Carcinogens; Enzyme Inhibitors; Fecal Incontinence; Indoles; Maleimides; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Rectum; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction

2013