phorbol 12,13-dibutyrate has been researched along with ucn 1028 c in 60 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 31 (51.67) | 18.2507 |
2000's | 24 (40.00) | 29.6817 |
2010's | 5 (8.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Bruns, RF; Heath, WF; Howbert, JJ; Kobayashi, E; Merriman, RL; Miller, FD; Nakano, H; Takahashi, I; Tamaoki, T | 1 |
Areces, LB; Blumberg, PM; Kazanietz, MG | 1 |
Mühl, H; Pfeilschifter, J | 1 |
Cano, C; Malik, KU; Slavik, KJ | 1 |
Budworth, J; Gescher, A | 1 |
Argent, BE; Gray, MA; McAlroy, HL; Winpenny, JP | 1 |
Blumberg, PM; Bruns, JD; Kazanietz, MG; Lewin, NE | 1 |
Giaid, A; Harrison, DG; Kurz, S; Münzel, T; Stewart, DJ | 1 |
Kopp, UC; Smith, LA | 1 |
Daniel, EE; Kwan, CY; Shimamoto, H; Shimamoto, Y | 1 |
Didion, SP; Mayhan, WG | 1 |
Burt, RP; Chapple, CR; Marshall, I | 1 |
Cohen, ML; Cox, DA | 1 |
Kan, H; Malik, KU; Ruan, Y | 1 |
Kamei, J; Mizoguchi, H; Narita, M; Ohsawa, M; Tseng, LF | 1 |
Nash, MS; Osborne, NN; Wood, JP | 1 |
Goodyer, CG; Oh, LY; Olivier, A; Yong, VW | 1 |
Fung, H; Heintz, NH; Jaken, S; Janssen, YM; Marsh, JP; Mossman, BT; Quinlan, TR; Taatjes, DJ; Timblin, CR; Vacek, P | 1 |
Keiser, HR; Oriji, GK | 1 |
Bun, T; Kawamata, T; Peterson, JW; Zervas, NT | 1 |
Hano, T; Kimura, K; Nishio, I; Sasajima, H; Shima, H; Toyoda, Y; Yoshikawa, A | 1 |
Dent, G; Leff, AR; Magnussen, H; Muñoz, NM; Rabe, KF; Rühlmann, E; Zhu, X | 1 |
Kamei, J; Ohsawa, M | 3 |
Breuiller-Fouché, M; Ferré, F; Fournier, T; Héluy, V; Tertrin-Clary, C | 1 |
Fukao, M; Hattori, Y; Kanno, M; Kitabatake, A; Sakuma, I; Sato, A | 1 |
Hattori, Y; Kanno, M; Kitabatake, A; Kohya, T; Moriishi, K; Oguma, K; Sasaki, M; Tomita, F | 1 |
Nicolás, JM; Renard-Rooney, DC; Thomas, AP | 1 |
Dessauer, CW; Hume, JR; Keef, KD; Zhong, J | 1 |
Inoue, T; Koono, M; Nabeshima, K; Shimao, Y | 1 |
Hitosugi, H; Kamei, J; Ohsawa, M | 1 |
Sanders, JL; Stern, PH | 1 |
Chen, C; Clarke, IJ; Loneragan, K; Roh, SG; Ruan, M; Xu, R | 1 |
Brandon, NJ; Brown, DA; Delmas, P; Kittler, JT; McDonald, BJ; Moss, SJ; Sieghart, W; Smart, TG | 1 |
Björklund, S; Dugué, B; Titievsky, A; Törnquist, K; Tuominen, RK; Vainio, PJ | 1 |
Cantwell, AM; Long, W; Longo, LD; Miguel, C; Nanyonga, AT; Saito, T; Windemuth, RS; Zhang, L; Zhao, Y | 1 |
Brown, PD; Kajita, H; Whitwell, C | 1 |
Breuiller-Fouché, M; Cabrol, D; Eude, I; Ferré, F; Paris, B | 1 |
Coats, P; Hillier, C; Johnston, F; MacDonald, J; McMurray, JJ | 1 |
Jun, JY; Koh, SD; Kong, ID; Perrino, BA; Sanders, KM; Wang, XY; Ward, SM | 1 |
Deth, RC; Sharma, A; Waly, M | 1 |
Cho, H; Earm, YE; Ho, WK; Youm, JB | 1 |
Iguchi, E; Kamei, J; Morita, K; Sasaki, M; Tanaka, S; Zushida, K | 1 |
Cavallero, S; Damiano, P; de la Riva, I; Fernández, B; Mayer, M; Puyó, AM; Rosón, MI | 1 |
Callaghan, B; Keef, KD; Koh, SD | 1 |
Burnstock, G; Smith, NC | 1 |
Chiba, Y; Hirano, T; Misawa, M; Sakai, H; Takeyama, H | 1 |
Khisti, RT; Kumar, S; Morrow, AL | 1 |
Abe, K; Hoshi, K; Ishikawa, M; Matsushita, Y; Quock, RM; Taguchi, K; Utsunomiya, I | 1 |
Bildin, VN; Mergler, S; Reinach, PS; Wang, Z; Wen, Q; Yang, H; Zhang, F | 1 |
Furness, JB; Poole, DP | 1 |
Balfagón, G; Blanco-Rivero, J; Ferrer, M; Sagredo, A | 1 |
Kim, YK | 1 |
Abebe, W; Mozaffari, MS | 1 |
Heaps, CL; Parker, JL; Robles, JC; Sturek, M | 1 |
Maxwell, PJ; Rattan, S; Singh, J | 1 |
Bosco, AA; Mattos, RT; Nogueira-Machado, JA | 1 |
Paisansathan, C; Pelligrino, DA; Vetri, F; Xu, H | 1 |
Rattan, S; Singh, J | 1 |
60 other study(ies) available for phorbol 12,13-dibutyrate and ucn 1028 c
Article | Year |
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Inhibition of protein kinase C by calphostin C is light-dependent.
Topics: Animals; Brain; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Darkness; Down-Regulation; ErbB Receptors; Humans; Kinetics; Light; Naphthalenes; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Protein Kinase C; Rats; Rats, Inbred Strains | 1991 |
Close similarity of baculovirus-expressed n-chimaerin and protein kinase C alpha as phorbol ester receptors.
Topics: Amino Acid Sequence; Animals; Baculoviridae; Base Sequence; Caenorhabditis elegans Proteins; Carrier Proteins; Cells, Cultured; Chimerin 1; Isoenzymes; Molecular Sequence Data; Moths; Naphthalenes; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Phosphatidylserines; Phospholipids; Polycyclic Compounds; Protein Kinase C; Protein Kinase C-alpha; Receptors, Drug; Sphingosine | 1994 |
Possible role of protein kinase C-epsilon isoenzyme in inhibition of interleukin 1 beta induction of nitric oxide synthase in rat renal mesangial cells.
Topics: Amino Acid Oxidoreductases; Animals; Blotting, Northern; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Induction; Glomerular Mesangium; Interleukin-1; Isoenzymes; NADH Dehydrogenase; Naphthalenes; Nitric Oxide Synthase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Polycyclic Compounds; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 1994 |
Loss of adenosine-induced negative inotropic effect in hyperexcited rabbit hearts: relationship to PKC.
Topics: Acetylcholine; Adenosine; Angiotensin II; Animals; Behavior, Animal; Biphenyl Compounds; Blood Pressure; Depression, Chemical; Enzyme Activation; Heart Rate; Imidazoles; In Vitro Techniques; Losartan; Male; Myocardial Contraction; Naphthalenes; Norepinephrine; Perfusion; Phentolamine; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Propranolol; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Tetrazoles | 1995 |
Differential inhibition of cytosolic and membrane-derived protein kinase C activity by staurosporine and other kinase inhibitors.
Topics: Alkaloids; Breast Neoplasms; Cell Membrane; Cytosol; Humans; Immunoblotting; Indoles; Naphthalenes; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tumor Cells, Cultured | 1995 |
Protein kinase C regulates the magnitude and stability of CFTR currents in pancreatic duct cells.
Topics: Animals; Cells, Cultured; Chloride Channels; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Membrane Proteins; Naphthalenes; Pancreatic Ducts; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Protein Kinase C; Rats | 1995 |
Characterization of the cysteine-rich region of the Caenorhabditis elegans protein Unc-13 as a high affinity phorbol ester receptor. Analysis of ligand-binding interactions, lipid cofactor requirements, and inhibitor sensitivity.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bryostatins; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Cysteine; DNA Primers; Helminth Proteins; Lactones; Ligands; Macrolides; Molecular Sequence Data; Naphthalenes; Phorbol 12,13-Dibutyrate; Phospholipids; Polycyclic Compounds; Protein Kinase C; Receptors, Drug; Recombinant Proteins | 1995 |
Evidence for a role of endothelin 1 and protein kinase C in nitroglycerin tolerance.
Topics: Alkaloids; Angiotensin II; Animals; Aorta, Thoracic; Drug Tolerance; Endothelins; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Nitroglycerin; Phenylephrine; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Potassium Chloride; Protein Kinase C; Rabbits; Serotonin; Staurosporine; Vasoconstriction | 1995 |
A role for protein kinase C in bradykinin-mediated activation of renal pelvic sensory receptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bradykinin; Enzyme Activation; Isoquinolines; Kidney Pelvis; Male; Naphthalenes; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Staurosporine | 1995 |
Differential effects of putative protein kinase C inhibitors on contraction of rat aortic smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Aorta; Dose-Response Relationship, Drug; Isoquinolines; Male; Muscle, Smooth, Vascular; Naphthalenes; Phenylephrine; Phorbol 12,13-Dibutyrate; Piperazines; Polycyclic Compounds; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Vasoconstriction | 1993 |
Activation of protein kinase C does not participate in disruption of the blood-brain barrier to albumin during acute hypertension.
Topics: Acute Disease; Animals; Blood Pressure; Blood-Brain Barrier; Capillary Permeability; Enzyme Activation; Enzyme Inhibitors; Hypertension; Male; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sphingosine | 1995 |
The role of diacylglycerol and activation of protein kinase C in alpha 1A-adrenoceptor-mediated contraction to noradrenaline of rat isolated epididymal vas deferens.
Topics: Animals; Calcium; Carcinogens; Cyclohexanones; Diglycerides; Lipoprotein Lipase; Male; Naphthalenes; Norepinephrine; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Staurosporine; Thiazoles; Vas Deferens | 1996 |
Lysophosphatidylcholine stimulates phospholipase D in human coronary endothelial cells: role of PKC.
Topics: Alkaloids; Benzophenanthridines; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Humans; Indoles; Lysophosphatidylcholines; Maleimides; Naphthalenes; Phenanthridines; Phorbol 12,13-Dibutyrate; Phospholipase D; Protein Kinase C | 1996 |
Involvement of mitogen-activated protein kinase and translocation of cytosolic phospholipase A2 to the nuclear envelope in acetylcholine-induced prostacyclin synthesis in rabbit coronary endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Amino Acid Sequence; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Cells, Cultured; Coronary Vessels; Cytosol; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Molecular Sequence Data; Naphthalenes; Nitriles; Nitrophenols; Nuclear Envelope; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Phosphorylation; Rabbits; Tetradecanoylphorbol Acetate; Tyrphostins | 1996 |
Pretreatment with protein kinase C activator phorbol 12,13-dibutyrate attenuates the antinociception induced by mu- but not epsilon-opioid receptor agonist in the mouse.
Topics: Analgesics; Animals; beta-Endorphin; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Activation; Enzyme Inhibitors; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naphthalenes; Nociceptors; Pain Measurement; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Opioid; Receptors, Opioid, mu; Time Factors | 1997 |
Protein kinase C activation by serotonin potentiates agonist-induced stimulation of cAMP production in cultured rat retinal pigment epithelial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Isoproterenol; Naphthalenes; Phorbol 12,13-Dibutyrate; Pigment Epithelium of Eye; Protein Kinase C; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Staurosporine | 1997 |
The promoting effects of bFGF and astrocyte extracellular matrix on process outgrowth by adult human oligodendrocytes are mediated by protein kinase C.
Topics: Astrocytes; Cells, Cultured; Enzyme Inhibitors; Extracellular Matrix; Fibroblast Growth Factor 2; Humans; Naphthalenes; Oligodendroglia; Phorbol 12,13-Dibutyrate; Protein Kinase C; Staurosporine | 1997 |
Inhibition of protein kinase C prevents asbestos-induced c-fos and c-jun proto-oncogene expression in mesothelial cells.
Topics: Animals; Asbestos; Benzoquinones; Epithelium; Gene Expression; Isoenzymes; Lactams, Macrocyclic; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Quinones; Rats; Rats, Inbred F344; Rifabutin; RNA, Messenger; Time Factors | 1997 |
Protein kinase C mediates angiotensin II-induced contractions and the release of endothelin and prostacyclin in rat aortic rings.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Epoprostenol; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Osmolar Concentration; Peptides, Cyclic; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Staurosporine; Vasoconstrictor Agents | 1997 |
Augmentation of both hemolysate-induced contraction and activation of protein kinase C by submaximum activation in canine cerebral arteries in vitro.
Topics: Animals; Cell Membrane; Cerebral Arteries; Chronic Disease; Cytosol; Dogs; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Hemolysis; Ischemic Attack, Transient; Membrane Potentials; Muscle, Smooth, Vascular; Naphthalenes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Potassium; Protein Binding; Protein Kinase C; Stress, Mechanical; Subarachnoid Hemorrhage; Vasoconstriction; Vasoconstrictor Agents | 1997 |
Increased Ca2+ sensitivity of contractile elements via protein kinase C in alpha-toxin permeabilized SMA from young spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analysis of Variance; Animals; Calcium; Enzyme Inhibitors; In Vitro Techniques; Male; Mesenteric Artery, Superior; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Staphylococcus aureus; Type C Phospholipases | 1997 |
Protein kinase C inhibition enhances platelet-activating factor-induced eicosanoid production in human eosinophils.
Topics: Arachidonic Acid; Calcium; Catalase; Eicosanoids; Enzyme Inhibitors; Eosinophils; Female; Humans; Indoles; Leukotriene C4; Male; Maleimides; Naphthalenes; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1998 |
Possible involvement of protein kinase C in the attenuation of [D-Ala2, NMePhe4, Gly-ol5]enkephalin-induced antinociception in diabetic mice.
Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Inhibitors; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naphthalenes; Nociceptors; Phorbol 12,13-Dibutyrate; Protein Kinase C; Reference Values | 1997 |
Role of protein kinase C in endothelin-1-induced contraction of human myometrium.
Topics: Adult; Cytosol; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Isoenzymes; Middle Aged; Myometrium; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Uterine Contraction | 1998 |
A role of myofilament Ca2+ sensitivity in enhanced vascular reactivity in cardiomyopathic hamsters.
Topics: Actin Cytoskeleton; Angiotensin II; Animals; Aorta; Calcium; Calcium Channel Blockers; Cardiomyopathies; Cricetinae; Indoles; Male; Mesocricetus; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Nifedipine; Phenylephrine; Phorbol 12,13-Dibutyrate; Potassium; Ryanodine; Staurosporine; Vasoconstrictor Agents | 1998 |
Tyrosine phosphorylation as a convergent pathway of heterotrimeric G protein- and rho protein-mediated Ca2+ sensitization of smooth muscle of rabbit mesenteric artery.
Topics: Adenosine Diphosphate; ADP Ribose Transferases; Animals; Botulinum Toxins; Calcium; Carcinogens; Dimerization; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phenylephrine; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; rho GTP-Binding Proteins; Ribose; Staurosporine; Tyrosine; Tyrphostins; Vasoconstrictor Agents | 1998 |
Tonic regulation of excitation-contraction coupling by basal protein kinase C activity in isolated cardiac myocytes.
Topics: Animals; Caffeine; Calcium-Transporting ATPases; Contractile Proteins; Enzyme Inhibitors; Heart; In Vitro Techniques; Kinetics; Magnesium; Male; Microscopy, Fluorescence; Myocardial Contraction; Myocardium; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sarcolemma; Sarcoplasmic Reticulum; Staurosporine; Time Factors | 1998 |
Regulation of L-type Ca2+ channels in rabbit portal vein by G protein alphas and betagamma subunits.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Proteins; In Vitro Techniques; Indoles; Male; Maleimides; Models, Biological; Muscle, Smooth, Vascular; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Portal Vein; Protein Conformation; Protein Kinase C; Pyrroles; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thionucleotides | 1999 |
Modification of the expression of naloxone-precipitated withdrawal signs in morphine-dependent mice by diabetes: possible involvement of protein kinase C.
Topics: Animals; Behavior, Animal; Carbazoles; Carcinogens; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Frontal Lobe; Indoles; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Naloxone; Naphthalenes; Narcotic Antagonists; Narcotics; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrroles; Substance Withdrawal Syndrome | 1999 |
Possible involvement of spinal protein kinase C in thermal allodynia and hyperalgesia in diabetic mice.
Topics: Analysis of Variance; Animals; Capsaicin; Carbazoles; Carcinogens; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus; Enzyme Inhibitors; Hot Temperature; Hyperalgesia; Indoles; Male; Mice; Mice, Inbred ICR; Naphthalenes; Pain; Pain Measurement; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrroles; Spinal Cord | 1999 |
TPA-enhanced motility and invasion in a highly metastatic variant (L-10) of human rectal adenocarcinoma cell line RCM-1: selective role of PKC-alpha and its inhibition by a combination of PDBu-induced PKC downregulation and antisense oligonucleotides trea
Topics: Adenocarcinoma; Base Sequence; Carbazoles; Down-Regulation; Humans; Indoles; Isoenzymes; Naphthalenes; Neoplasm Invasiveness; Neoplasm Metastasis; Oligonucleotides, Antisense; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Protein Kinase C-alpha; Rectal Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Effect of diabetes on bradykinin-induced thermal hyperalgesia in mice.
Topics: Animals; Bradykinin; Diabetes Mellitus, Experimental; Enzyme Activators; Enzyme Inhibitors; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Reaction Time | 2000 |
Protein kinase C involvement in interleukin-6 production by parathyroid hormone and tumor necrosis factor-alpha in UMR-106 osteoblastic cells.
Topics: Animals; Cell Line; Cyclic AMP; Down-Regulation; Interleukin-6; Naphthalenes; Osteoblasts; Parathyroid Hormone; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Tumor Necrosis Factor-alpha | 2000 |
Diverse intracellular signalling systems used by growth hormone-releasing hormone in regulating voltage-gated Ca2+ or K channels in pituitary somatotropes.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcium Channels; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Growth Hormone-Releasing Hormone; Humans; Isoquinolines; Naphthalenes; Patch-Clamp Techniques; Phenanthridines; Phorbol 12,13-Dibutyrate; Pituitary Gland; Potassium Channels; Protein Kinase C; Sheep; Signal Transduction; Sulfonamides | 2000 |
GABAA receptor phosphorylation and functional modulation in cortical neurons by a protein kinase C-dependent pathway.
Topics: Animals; Cell Line; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Humans; Kinetics; Naphthalenes; Neurons; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinases; Protein Subunits; Pyramidal Cells; Rats; Receptors, GABA-A; Recombinant Proteins; Serine; Signal Transduction; Transfection | 2000 |
Hydrogen peroxide attenuates store-operated calcium entry and enhances calcium extrusion in thyroid FRTL-5 cells.
Topics: Adenosine Triphosphate; Animals; Barium; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cell Line; Down-Regulation; Enzyme Activation; Hydrogen Peroxide; Isoenzymes; Manganese; Membrane Potentials; Mercaptoethanol; Naphthalenes; Oxidation-Reduction; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Transport; Rats; Sodium; Staurosporine; Thapsigargin; Thyroid Gland | 2000 |
Dual role of PKC in modulating pharmacomechanical coupling in fetal and adult cerebral arteries.
Topics: Animals; Cell Membrane; Cerebral Arteries; Enzyme Inhibitors; Feedback; Fetus; Indoles; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Lactams; Naphthalenes; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Sheep; Signal Transduction; Staurosporine; Vasoconstriction | 2000 |
Properties of the inward-rectifying Cl- channel in rat choroid plexus: regulation by intracellular messengers and inhibition by divalent cations.
Topics: Adenosine Triphosphate; Animals; Cadmium; Cations, Divalent; Chloride Channels; Choroid Plexus; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Electric Conductivity; Electrodes; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Solutions; Tetradecanoylphorbol Acetate; Zinc | 2000 |
Selective protein kinase C isoforms are involved in endothelin-1-induced human uterine contraction at the end of pregnancy.
Topics: Blotting, Western; Carbazoles; Chelating Agents; Cytosol; Down-Regulation; Egtazic Acid; Endothelin-1; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Indoles; Isoenzymes; Myometrium; Naphthalenes; Phorbol 12,13-Dibutyrate; Pregnancy; Protein Kinase C; Receptors for Activated C Kinase; Receptors, Cell Surface; Uterine Contraction | 2000 |
Signalling mechanisms underlying the myogenic response in human subcutaneous resistance arteries.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aged; Analysis of Variance; Arteries; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cyclohexanones; Enzyme Inhibitors; Estrenes; Female; Humans; In Vitro Techniques; Indoles; Lipoprotein Lipase; Male; Middle Aged; Muscle, Smooth, Vascular; Naphthalenes; Nifedipine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrrolidinones; Ryanodine; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Type C Phospholipases; Vascular Resistance | 2001 |
Regulation of ATP-sensitive K(+) channels by protein kinase C in murine colonic myocytes.
Topics: Acetylcholine; Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Colon; Enzyme Activation; Enzyme Inhibitors; Female; Glyburide; In Vitro Techniques; Isoenzymes; Kinetics; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Muscle, Smooth; Naphthalenes; Patch-Clamp Techniques; Phenanthridines; Phorbol 12,13-Dibutyrate; Pinacidil; Potassium Channels; Protein Kinase C; Protein Kinase C-epsilon | 2001 |
Protein kinase C regulates dopamine D4 receptor-mediated phospholipid methylation.
Topics: Alkaloids; Benzophenanthridines; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Methylation; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phenanthridines; Phorbol 12,13-Dibutyrate; Phospholipids; Protein Kinase C; Receptors, Dopamine D2; Receptors, Dopamine D4; Thionucleotides; Tumor Cells, Cultured | 2001 |
Inhibition of acetylcholine-activated K(+) current by chelerythrine and bisindolylmaleimide I in atrial myocytes from mice.
Topics: Acetylcholine; Alkaloids; Animals; Atrial Function; Benzophenanthridines; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Heart Atria; Indoles; Maleimides; Membrane Potentials; Mice; Naphthalenes; Patch-Clamp Techniques; Phenanthridines; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C | 2001 |
Modification of the fenvalerate-induced nociceptive response in mice by diabetes.
Topics: Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enzyme Activators; Enzyme Inhibitors; Hindlimb; Injections, Spinal; Male; Mexiletine; Mice; Mice, Inbred ICR; Naphthalenes; Nitriles; Pain Measurement; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrethrins; Sodium Channels; Streptozocin | 2002 |
Impaired response to insulin associated with protein kinase C in chronic fructose-induced hypertension.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Enzyme Activators; Enzyme Inhibitors; Fructose; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley | 2002 |
Muscarinic M2 receptor stimulation of Cav1.2b requires phosphatidylinositol 3-kinase, protein kinase C, and c-Src.
Topics: Acetylcholine; Animals; Barium; Calcium Channels, L-Type; Carbazoles; Cells, Cultured; Chromones; Class Ib Phosphatidylinositol 3-Kinase; Diamines; Enzyme Inhibitors; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Indoles; Ion Channel Gating; Ion Transport; Isoenzymes; Male; Morpholines; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Portal Vein; Protein Kinase C; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Rabbits; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Signal Transduction | 2004 |
Mechanisms underlying postjunctional synergism between responses of the vas deferens to noradrenaline and ATP.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Cantharidin; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Histamine; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; Muscle, Smooth; Naphthalenes; Norepinephrine; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Prazosin; Protein Kinase C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; rho-Associated Kinases; Vas Deferens | 2004 |
Acetylcholine-induced phosphorylation of CPI-17 in rat bronchial smooth muscle: the roles of Rho-kinase and protein kinase C.
Topics: Acetylcholine; Animals; Bronchi; Enzyme Inhibitors; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle Proteins; Muscle, Smooth; Myosin Light Chains; Naphthalenes; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; rho-Associated Kinases; Type C Phospholipases; Vasodilator Agents | 2005 |
Regulation of native GABAA receptors by PKC and protein phosphatase activity.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; GABA Agonists; gamma-Aminobutyric Acid; Isotopes; Male; Microcystins; Muscimol; Naphthalenes; Peptides, Cyclic; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2005 |
Involvement of brain protein kinase C in nitrous oxide-induced antinociception in mice.
Topics: Analgesics; Analysis of Variance; Animals; Blotting, Western; Brain; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Male; Mice; Mice, Inbred C57BL; Naphthalenes; Nitrous Oxide; Nociceptors; Pain Measurement; Phorbol 12,13-Dibutyrate; Protein Kinase C | 2006 |
PKC isoform-specific enhancement of capacitative calcium entry in human corneal epithelial cells.
Topics: Blotting, Western; Calcium; Calcium Channels; Cell Line; Epidermal Growth Factor; Epithelium, Corneal; Fura-2; Gene Deletion; Humans; Isoenzymes; Microscopy, Fluorescence; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-delta; RNA, Small Interfering; Transfection | 2006 |
PKC delta-isoform translocation and enhancement of tonic contractions of gastrointestinal smooth muscle.
Topics: Animals; Carbachol; Cytoplasm; Cytoskeleton; Diacylglycerol Kinase; Diterpenes; Female; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Isoenzymes; Male; Maleimides; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Transport; Scopolamine; Subcellular Fractions | 2007 |
Protein kinase C activation increases endothelial nitric oxide release in mesenteric arteries from orchidectomized rats.
Topics: Acetylcholine; Animals; Blotting, Western; Carbazoles; Dose-Response Relationship, Drug; Enzyme Activation; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Orchiectomy; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Superoxides; Thromboxane A2; Vasodilator Agents | 2007 |
TGF-beta1 induction of p21WAF1/cip1 requires smad-independent protein kinase C signaling pathway.
Topics: Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Dimethyl Sulfoxide; Genes, Reporter; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Immunoblotting; Immunohistochemistry; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1; Tubulin | 2007 |
Vascular reactivity changes in glucose-intolerant rat.
Topics: Acetylcholine; Animals; Animals, Newborn; Aorta; Blood Glucose; Body Weight; Calcium; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Egtazic Acid; Glucose Intolerance; Glucose Tolerance Test; In Vitro Techniques; Male; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitroprusside; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Inbred WKY; Serotonin; Vasoconstriction; Vasodilation | 2007 |
Ca2+ sensitization and PKC contribute to exercise training-enhanced contractility in porcine collateral-dependent coronary arteries.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Calcium; Collateral Circulation; Coronary Vessels; Endothelin-1; Enzyme Inhibitors; Female; Muscle Contraction; Naphthalenes; Phorbol 12,13-Dibutyrate; Physical Conditioning, Animal; Protein Kinase C; Pyridines; rho-Associated Kinases; Swine; Vasodilator Agents | 2011 |
Immunocytochemical evidence for PDBu-induced activation of RhoA/ROCK in human internal anal sphincter smooth muscle cells.
Topics: ADP Ribose Transferases; Amides; Anal Canal; Botulinum Toxins; Cells, Cultured; Fluorescent Antibody Technique; Humans; Muscle Contraction; Myocytes, Smooth Muscle; Myosin-Light-Chain Phosphatase; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C-alpha; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2011 |
Rosiglitazone, a PPAR-γ agonist, inhibits VEGF secretion by peripheral blood mononuclear cells and ROS production by human leukocytes.
Topics: Adult; Humans; Hypoglycemic Agents; Leukocytes; Leukocytes, Mononuclear; Luminescence; Middle Aged; Naphthalenes; Phorbol 12,13-Dibutyrate; PPAR gamma; Protein Kinase C; Reactive Oxygen Species; Rosiglitazone; Thiazolidinediones; Vascular Endothelial Growth Factor A | 2012 |
Impairment of neurovascular coupling in type 1 diabetes mellitus in rats is linked to PKC modulation of BK(Ca) and Kir channels.
Topics: Animals; Arterioles; Benzimidazoles; Cerebrovascular Circulation; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Electric Stimulation; Enzyme Activation; Enzyme Activators; Female; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Naphthalenes; Phorbol 12,13-Dibutyrate; Phosphorylation; Pia Mater; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Time Factors; Vasodilation | 2012 |
Role of PKC and RhoA/ROCK pathways in the spontaneous phasic activity in the rectal smooth muscle.
Topics: Amides; Animals; Carcinogens; Enzyme Inhibitors; Fecal Incontinence; Indoles; Maleimides; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Rectum; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2013 |