Page last updated: 2024-08-23

phorbol 12,13-dibutyrate and tyrosine

phorbol 12,13-dibutyrate has been researched along with tyrosine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's17 (73.91)18.2507
2000's4 (17.39)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gaudry, M; Gilbert, C; Naccache, PH1
Bonser, RW; Garland, LG; Hudson, AT; Randall, RW; Spacey, GD; Thompson, NT; Uings, IJ1
Gold, MR; Pelech, SL; Sanghera, JS; Stewart, J1
Friedman, B; Fujiki, H; Rosner, MR1
Brunswick, M; Mond, JJ; Samelson, LE1
Rozengurt, E; Sinnett-Smith, J; Zachary, I1
Edgeworth, J; Freemont, P; Hogg, N1
Anderson, DC; Brown, EJ; Graham, IL; Holers, VM1
Nakamura, S; Nishizuka, Y; Ogita, K; Yamaguchi, K1
Crouch, MF; Hendry, IA1
Caon, AC; Gaudry, M; Naccache, PH1
Colussi, DJ; Merkel, LA; Perrone, MH; Rivera, LM1
Richardson, AF; Sando, JJ1
Rozengurt, E; Sinnett-Smith, J; Valverde, AM; Zachary, I1
Morrison, P; Rosner, MR; Saltiel, AR1
Epstein, RJ; Gulliford, T; Ouyang, X1
Hattori, Y; Kanno, M; Kitabatake, A; Kohya, T; Moriishi, K; Oguma, K; Sasaki, M; Tomita, F1
Borowski, P; Kühl, R; Laufs, R; Medem, S; Roloff, S1
Blumberg, PM; Garfield, SH; Lewin, NE; Marquez, VE; Nacro, K; Nicklaus, MC; Pearce, LL; Sigano, DM; Yan, S1
Kruger, JS; Reddy, KB1
Nozu, F; Tsunoda, Y; Yoshida, H1
Eves, R; Mak, AS; Webb, BA; Zhou, S1
Berk, BC; Menon, P; Pang, J; Smolock, EM; Wang, J; Yan, C; Yin, G1

Other Studies

23 other study(ies) available for phorbol 12,13-dibutyrate and tyrosine

ArticleYear
Rapid priming of calcium mobilization and superoxide anion production in human neutrophils by substimulatory concentrations of phorbol esters: a novel role for protein kinase C and tyrosine phosphorylation in the up-modulation of signal transduction.
    Cellular signalling, 1992, Volume: 4, Issue:5

    Topics: Adult; Calcium; Humans; Hydroquinones; In Vitro Techniques; Indoles; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Superoxides; Tyrosine; Up-Regulation

1992
Tyrosine phosphorylation is involved in receptor coupling to phospholipase D but not phospholipase C in the human neutrophil.
    The Biochemical journal, 1992, Feb-01, Volume: 281 ( Pt 3)

    Topics: Enzyme Activation; Humans; Indoles; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipase D; Phosphoric Diester Hydrolases; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Cell Surface; Type C Phospholipases; Tyrosine

1992
Selective activation of p42 mitogen-activated protein (MAP) kinase in murine B lymphoma cell lines by membrane immunoglobulin cross-linking. Evidence for protein kinase C-independent and -dependent mechanisms of activation.
    The Biochemical journal, 1992, Oct-01, Volume: 287 ( Pt 1)

    Topics: Amino Acid Sequence; Animals; B-Lymphocytes; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; In Vitro Techniques; Lymphoma, B-Cell; Mice; Molecular Sequence Data; Phorbol 12,13-Dibutyrate; Phosphotyrosine; Protein Kinase C; Proteins; Receptor Aggregation; Receptors, Antigen, B-Cell; Signal Transduction; Substrate Specificity; Tumor Cells, Cultured; Tyrosine

1992
Regulation of the epidermal growth factor receptor by growth-modulating agents: effects of staurosporine, a protein kinase inhibitor.
    Cancer research, 1990, Feb-01, Volume: 50, Issue:3

    Topics: Alkaloids; Animals; Calcimycin; Epidermal Growth Factor; ErbB Receptors; Humans; Mice; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Staurosporine; Tumor Cells, Cultured; Tyrosine

1990
Surface immunoglobulin crosslinking activates a tyrosine kinase pathway in B cells that is independent of protein kinase C.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Feb-15, Volume: 88, Issue:4

    Topics: Animals; Antibodies, Monoclonal; B-Lymphocytes; Blotting, Western; Cross-Linking Reagents; Ionomycin; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Spleen; Tyrosine

1991
Stimulation of tyrosine kinase activity in anti-phosphotyrosine immune complexes of Swiss 3T3 cell lysates occurs rapidly after addition of bombesin, vasopressin, and endothelin to intact cells.
    The Journal of biological chemistry, 1991, Dec-15, Volume: 266, Issue:35

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Antigen-Antibody Complex; Bombesin; Calcimycin; Cell-Free System; Endothelins; Gastrins; Kinetics; Mice; Molecular Sequence Data; Molecular Weight; Neuropeptides; Peptides; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Substrate Specificity; Tyrosine; Vanadates; Vasopressins

1991
Ionomycin-regulated phosphorylation of the myeloid calcium-binding protein p14.
    Nature, 1989, Nov-09, Volume: 342, Issue:6246

    Topics: Amino Acid Sequence; Calcium; Calcium-Binding Proteins; Electrophoresis, Gel, Two-Dimensional; Humans; Ionomycin; Molecular Sequence Data; Monocytes; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphotyrosine; Signal Transduction; Tyrosine

1989
Complement receptor 3 (CR3, Mac-1, integrin alpha M beta 2, CD11b/CD18) is required for tyrosine phosphorylation of paxillin in adherent and nonadherent neutrophils.
    The Journal of cell biology, 1994, Volume: 127, Issue:4

    Topics: Adolescent; Adult; CD18 Antigens; Cell Adhesion; Cell Line; Cytoskeletal Proteins; Extracellular Matrix Proteins; Female; Humans; In Vitro Techniques; Integrins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Paxillin; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Phosphotyrosine; Receptors, Complement; Signal Transduction; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine

1994
The protein kinase C isoforms leading to MAP-kinase activation in CHO cells.
    Biochemical and biophysical research communications, 1995, May-25, Volume: 210, Issue:3

    Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; CHO Cells; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Cricetinae; Cytosol; Durapatite; Enzyme Activation; Immunoblotting; Isoenzymes; Kinetics; Molecular Sequence Data; Phorbol 12,13-Dibutyrate; Phosphotyrosine; Protein Kinase C; Tetradecanoylphorbol Acetate; Tyrosine

1995
Gi alpha and Gi beta are part of a signalling complex in Balb/c3T3 cells: phosphorylation of Gi beta in growth-factor-activated fibroblasts.
    Cellular signalling, 1993, Volume: 5, Issue:1

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Antibodies; Enzyme Activation; Epidermal Growth Factor; GTP-Binding Proteins; Insulin; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine; Virulence Factors, Bordetella

1993
Modulation of the activity and subcellular distribution of protein tyrosine kinases in human neutrophils by phorbol esters.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1993, Volume: 7, Issue:8

    Topics: Adult; Amino Acid Sequence; Humans; Indoles; Molecular Sequence Data; Neutrophils; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Subcellular Fractions; Tyrosine

1993
Inhibition of EGF-induced vasoconstriction in isolated rabbit aortic rings with the tyrosine kinase inhibitor RG50864.
    Biochemical and biophysical research communications, 1993, May-14, Volume: 192, Issue:3

    Topics: Animals; Aorta, Abdominal; Catechols; Dose-Response Relationship, Drug; Epidermal Growth Factor; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitriles; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Rabbits; Tyrosine; Tyrphostins; Vasoconstriction

1993
Rapid tyrosine phosphorylation of an 85,000 M(r) protein after phorbol ester stimulation of EL4 thymoma cells.
    Cellular signalling, 1995, Volume: 7, Issue:1

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cells, Cultured; Immunoblotting; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); MAP Kinase Kinase Kinase 1; Mice; Molecular Weight; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Signal Transduction; T-Lymphocytes; Thymus Gland; Tyrosine; ZAP-70 Protein-Tyrosine Kinase

1995
Bombesin stimulation of p125 focal adhesion kinase tyrosine phosphorylation. Role of protein kinase C, Ca2+ mobilization, and the actin cytoskeleton.
    The Journal of biological chemistry, 1993, Jul-05, Volume: 268, Issue:19

    Topics: 3T3 Cells; Actins; Animals; Bombesin; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Adhesion Molecules; Colchicine; Cytochalasin D; Cytoskeleton; Diglycerides; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Indoles; Intracellular Signaling Peptides and Proteins; Kinetics; Maleimides; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proteins; Terpenes; Thapsigargin; Tyrosine

1993
Role of mitogen-activated protein kinase kinase in regulation of the epidermal growth factor receptor by protein kinase C.
    The Journal of biological chemistry, 1996, May-31, Volume: 271, Issue:22

    Topics: 3T3 Cells; Animals; CHO Cells; Cricetinae; Cysteine; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Mice; Mitogen-Activated Protein Kinase Kinases; Mutagenesis, Site-Directed; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Terpenes; Thapsigargin; Tyrosine

1996
The duration of phorbol-inducible ErbB2 tyrosine dephosphorylation parallels that of receptor endocytosis rather than threonine-686 phosphorylation: implications for the physiological role of protein kinase C in growth factor receptor signalling.
    Carcinogenesis, 1998, Volume: 19, Issue:11

    Topics: 3T3 Cells; Adaptor Protein Complex alpha Subunits; Adaptor Proteins, Vesicular Transport; Animals; Endocytosis; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptor, ErbB-2; Receptors, Growth Factor; Threonine; Time Factors; Tyrosine

1998
Tyrosine phosphorylation as a convergent pathway of heterotrimeric G protein- and rho protein-mediated Ca2+ sensitization of smooth muscle of rabbit mesenteric artery.
    British journal of pharmacology, 1998, Volume: 125, Issue:8

    Topics: Adenosine Diphosphate; ADP Ribose Transferases; Animals; Botulinum Toxins; Calcium; Carcinogens; Dimerization; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phenylephrine; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; rho GTP-Binding Proteins; Ribose; Staurosporine; Tyrosine; Tyrphostins; Vasoconstrictor Agents

1998
Protein kinase C-alpha produces reciprocal effects on the phorbol ester stimulated tyrosine phosphorylation of a 50 kDa kinase in Jurkat cells.
    Biological chemistry, 1999, Volume: 380, Issue:4

    Topics: Adenosine; Affinity Labels; Cell Extracts; Enzyme Activation; Enzyme Inhibitors; Humans; Isoenzymes; Jurkat Cells; Kinetics; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Substrate Specificity; Tetradecanoylphorbol Acetate; Tyrosine

1999
An optimized protein kinase C activating diacylglycerol combining high binding affinity (Ki) with reduced lipophilicity (log P).
    Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12

    Topics: Animals; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Databases as Topic; Diglycerides; Enzyme Activation; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Conformation; Phorbol 12,13-Dibutyrate; Protein Conformation; Protein Kinase C; Protein Structure, Secondary; Recombinant Fusion Proteins; Structure-Activity Relationship; Transfection; Tryptophan; Tyrosine; Zinc Fingers

2001
Distinct mechanisms mediate the initial and sustained phases of cell migration in epidermal growth factor receptor-overexpressing cells.
    Molecular cancer research : MCR, 2003, Volume: 1, Issue:11

    Topics: Breast Neoplasms; Cell Division; Cell Line, Tumor; Cell Movement; ErbB Receptors; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Myosin-Light-Chain Kinase; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Serine-Threonine Kinases; rho-Associated Kinases; Transforming Growth Factor alpha; Tyrosine

2003
Receptor-operated Ca2+ influx and its association with the Src family in secretagogue-stimulated pancreatic acini.
    Biochemical and biophysical research communications, 2004, Feb-13, Volume: 314, Issue:3

    Topics: Amylases; Animals; Calcium; Cattle; Cholecystokinin; Enzyme Inhibitors; Fibroblast Growth Factors; Genes, src; Genistein; Humans; Ionomycin; Male; Pancreas; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, G-Protein-Coupled; Receptors, Ghrelin; Recombinant Proteins; Sodium Fluoride; Tyrosine

2004
Effects of tyrosine phosphorylation of cortactin on podosome formation in A7r5 vascular smooth muscle cells.
    American journal of physiology. Cell physiology, 2006, Volume: 290, Issue:2

    Topics: Animals; Carcinogens; Cell Line; Cell Shape; Cell Surface Extensions; Cortactin; Indoles; Maleimides; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C-alpha; Rats; RNA, Small Interfering; src-Family Kinases; Sulfonamides; Tyrosine

2006
Phosphorylation of G protein-coupled receptor kinase 2-interacting protein 1 tyrosine 392 is required for phospholipase C-gamma activation and podosome formation in vascular smooth muscle cells.
    Arteriosclerosis, thrombosis, and vascular biology, 2010, Volume: 30, Issue:10

    Topics: Actins; Animals; Cell Cycle Proteins; Cell Line; Cell Membrane Structures; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Mutant Proteins; Myocytes, Smooth Muscle; Phorbol 12,13-Dibutyrate; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Rats; Recombinant Proteins; RNA, Small Interfering; src-Family Kinases; Transfection; Tyrosine

2010