Page last updated: 2024-08-23

phorbol 12,13-dibutyrate and tetradecanoylphorbol acetate

phorbol 12,13-dibutyrate has been researched along with tetradecanoylphorbol acetate in 510 studies

Research

Studies (510)

TimeframeStudies, this research(%)All Research%
pre-1990225 (44.12)18.7374
1990's250 (49.02)18.2507
2000's28 (5.49)29.6817
2010's7 (1.37)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Irie, K; Kamachi, H; Murakami, A; Nagai, H; Nakagawa, Y; Tanaka, K; Tokuda, H; Yanagita, RC1
Imoto, M; Irie, K; Kawamura, T; Matsubara, K; Otaka, H; Shindo, K; Tashiro, E; Yanagita, RC1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Blumberg, PM; Comin, MJ; Donadío, LG; Esch, TE; Garcia, LC; Hill, CS; Jelinek, R; Kedei, N; Kelley, JA; Kelsey, JS; Kolusheva, S; Lewin, NE; Mann, E; Marquez, VE; Peach, ML; Santos, M; Yang, J1
Costa, J; Delang, L; Leyssen, P; Litaudon, M; Neyts, J; Nothias-Scaglia, LF; Pannecouque, C; Paolini, J; Renucci, F; Roussi, F1
Boscá, L; Genaro, AM; Hortelano, S1
Miwa, J; Sassa, T1
el Benna, J; Hakim, J; Labro, MT1
Ansari, NA; Wu, MC1
Akhtar, RA; Wilmoth, TL1
Croatto, M; Hamilton, JA; Phillips, WA; Veis, N1
Davis, JS1
Chen, CC1
Brownsey, RW; Olivier, M; Reiner, NE1
Bourinet, E; Charnet, P; Fournier, F; Lory, P; Nargeot, J1
Horio, T; Kohno, M; Murakawa, K; Takeda, T; Yasunari, K; Yokokawa, K1
Herrero, I; Miras-Portugal, MT; Sánchez-Prieto, J1
Myers, CL; Parks, T; Schembri-King, J; Wallace, RW; Wertheimer, SJ1
Gibson, IC; Logan, SD1
Huebert, C; Kuszynski, C; Rizzino, A; Wilder, PJ1
Jentel, JJ; Lacson, RG; Oehler, DT; Unterman, TG1
Kapus, A; Ligeti, E; Szászi, K1
Brooks, G; Goss, MW; Hart, IR1
Cook, PP; Garris, TO; Messer, BR; Parker, PJ; Qin, W; Ways, DK1
Herembert, T; Marche, P; Zhu, DL1
Blumberg, PM; Kazanietz, MG; Krausz, KW1
Bajnath, RB; de Jonge, HR; Groot, JA; van Hoeve, MH1
Asano, S; Harigaya, K; Takahashi, S; Uchimaru, K; Yamashita, T1
Nakashima, T; Satoh, H; Tsuchida, K1
Byrne, JH; Critz, SD1
Moffat, MP; Ward, CA1
Hazama, K; Igarashi, K; Kikkawa, U; Nishizuka, Y; Ogita, K; Ono, Y; Taniyama, Y; Watanabe, T1
Alkhalaf, B; Gong, Y; Murphy, LC; Murphy, LJ1
Chen, ZH; Gopalakrishna, R; Gundimeda, U4
Alkon, DL; Etcheberrigaray, R; Lederhendler, II; Matzel, LD1
Meldrum, BS; Smith, SE1
Cook, PP; Parker, PJ; Ways, DK; Webster, C1
Chuang, LF; Chuang, RY; Israel, M; Kung, HF1
Bittman, R; Davenport, R; Dryden, P; Howard, S; Jones, K; Salari, H1
Elsas, LJ; Griffin, LD; Langley, SD; Longo, N1
Giridhar, G; Hayakawa, H; Kucera, L; Myrvik, QN1
Basu, A; Kozikowski, AP; Lazo, JS1
Raufman, JP1
Basu, A; Lazo, JS1
Azula, FJ; Font, J; Macarulla, JM; Marino, A; Nieva, N; Trueba, M1
Davis, PD; Nixon, JS; Sedgwick, AD; Wadsworth, J; Westmacott, D; Wilkinson, SE1
Logan, A; Logan, SD1
Walsh, KB1
Canessa, ML; Conlin, PR; Williams, GH1
Feldman, D; Krishnan, AV1
Bervig, T; Braden, TD; Conn, PM1
Ransjö, M1
Lerner, UH; Ransjö, M1
Suen, CS; Wilk, S2
Blanchard, LM; Larose, L; Morisset, J; Paquette, B1
Sekino, H; Suzuki-Nishimura, T; Uchida, MK1
Fuller, BB; Hoganson, GE; Niekrasz, I1
Malamed, S; Perez, FM; Scanes, CG1
Armstrong, L; Molony, L1
Crow, MT; Schwartz, RJ; Zhu, YY1
Alberola-Ila, J; Lozano, F; Places, L; Vives, J1
Henrich, CJ; Messing, RO; Petersen, PJ1
Casillas, T; Delicado, EG; Miras-Portugal, MT; Sen, RP1
Higuchi, H; Hiraoka, N; Ito, M; Itoh, H; Konishi, T; Lederis, K; Nakano, T1
Janik, P; Miłoszewska, J; Szaniawska, B1
Arita, H; Hanasaki, K; Kishi, M1
Hess, AD; Levine, BL; May, WS; Tyler, PG1
Albers, FJ; Caron, MG; Dennis, VW; Lefkowitz, RJ; Middleton, JP; Obeid, LM; Raymond, JR1
Endou, M; Hattori, Y; Kanno, M; Tohse, N1
Banks, P; Monk, PN1
Doré, M; Neilsen, NR; Slauson, DO1
O'Brian, CA; Ward, NE1
Kato, H; Ozawa, J; Takata, Y1
Brostrom, CO; Brostrom, MA; Gmitter-Yellen, D; Grandison, LJ; Kuznetsov, G; Prostko, CR; Wong, WL1
Alexander, RW; Clark, M; Griendling, KK; Lassègue, B1
Chang, JP; de Leeuw, R; Jobin, RM1
Baumann, D; Lester, DS1
Lauwerys, R; Lison, D; Raguzzi, F1
Bertrand, F; Capeau, J; Cherqui, G; Garcia, I; Hermelin, B; Paul, A; Picard, J1
Fabbro, D; Imber, R1
Dempsey, EC; McMurtry, IF; O'Brien, RF1
Braquet, P; Ferber, E; Fischer, G; Harell, T; Her, E; Naor, Z; Reiss, N; Zor, U1
Harmody, D; Longley, RE1
Ramsdell, JS1
Holian, O; Kumar, R1
Butler, AP; Mar, PK; McDonald, FF; Ramsay, RL1
Dong, ZY; Fan, D; Gupta, KP; O'Brian, CA; Ward, NE1
Gonzalez, FA; Heppel, LA; Huang, NN; Wang, DJ1
Brooks, G; Dooley, TP; Goss, MW; Hart, IR; Wilson, RE1
Burch, RM; Connor, JR; Shearer, BG; Sullivan, JP; Tiffany, C1
Malcolm, AR; Mills, LJ; Robson, DL1
Alkon, DL; Etcheberrigaray, R; Lederhendler, II; Matzel, LD; Yamoah, EN1
Olianas, MC; Onali, P1
Anderson, DJ; Naor, Z; Sigmund, O; Stein, R1
Goode, NT; Hart, IR; Moore, JP1
Johnson, JD; Walters, JD1
de Feijter, AW; de Haan, LH; Homan, EC; Jongen, WM; Spaaij, C; van Aelst, AC; van der Zandt, PT1
Buxbaum, JD; Cicchetti, P; Czernik, AJ; Ehrlich, ME; Fracasso, RP; Gandy, SE; Greengard, P; Ramabhadran, TV; Unterbeck, AJ1
Gross, JL; Horuk, R1
Dösemeci, A; Gaa, ST; Massey, C; Rogers, TB1
Hirst, JJ; Jenkin, G; Rice, GE; Thorburn, GD1
el-Fakahany, EE; Lai, WS; Rogers, TB1
Huang, CL; Ives, HE; Lowe, JH1
de Boland, AR; Norman, A1
Pfeffer, LM; Saltiel, AR; Strulovici, B1
Chao, W; Hanahan, DJ; Liu, H; Olson, MS1
Harnett, MM; Klaus, GG1
Burstein, DE; Lacal, JC; Pellicer, A; Thomson, TM; Trotta, RJ1
Parker, PJ; Schaap, D1
Brunsing, D; Hensel, G; Krönke, M; Meichle, A; Schütze, S1
Choladze, MA; Kondratyev, AD; Popova, ON; Posypanova, GA; Severin, ES; Severin, SE; Shmyrev, II; Tubasheva, IA; Zotova, EE1
Bhat, NK; Fisher, RJ; Fujiwara, S; June, CH; Koizumi, S; Lindsten, T; Papas, TS; Thompson, CB1
Abel, KC; Clark, MG; Cleland, PJ; Rattigan, S1
Duronio, V; Jacobs, S1
McCann, JA; Messina, JL1
Bayard, F; Darbon, JM; Issandou, M; Jozan, S; Valette, A1
Clark, JC; Fink, I; Hull, WM; O'Reilly, MA; Pryhuber, GS; Whitsett, JA1
Foucart, S; Majewski, H; Musgrave, IF2
Bishop, JF; Gehlert, DR; Patel, J; Vyas, S1
Buckley, NE; Gibson, K; Spiegel, S; Zhang, H1
Hannun, YA; Karolak, LA; Obeid, LM; Okazaki, T1
Fredholm, B; Gullberg, M; Jondal, M; Kvanta, A; Nordstedt, C1
Huang, FL; Huang, KP; Labourdette, G; Malviya, AN; Masmoudi, A; Rogue, P; Vincendon, G; Yoshida, Y; Zwiller, J1
Imaizumi, S; McGinn, MT; Mullin, JM; Snock, KV1
Goode, NT; Hart, IR1
Ahluwalia, M; Bazan, E; Garver, D; Gruenstein, E; Johnson, CG; Johnson, CL1
Leissner, J; Lindmar, R; Löffelholz, K; Sandmann, J1
Akita, Y; Konno, Y; Ohno, S; Suzuki, K; Yano, A1
Heffner, CH; Long, MW; Peters, C; Prochownik, EV; Williams, JL1
Larsen, CS1
Baglioni, C; Johnson, SE1
Kalberg, CJ; Sumners, C1
Akerlind, G; Akerman, KE; Heikkilä, J; Jalava, AM; Pettit, GR1
Godson, C; Insel, PA; Weiss, BA1
Basu, A; Lazo, JS; Teicher, BA1
Alterman, RL; Kornblith, PL; Maleci, A; Moskal, JR; Sundstrom, D1
Ikebuchi, H; Saito, Y; Suzuki, K; Suzuki, S; Terao, T1
Guitart, X; Marsal, J; Solsona, C1
Ashendel, CL; Beltran, L; Davis, MM; DiGiovanni, J; Hirabayashi, N; Petersen-Marht, S; Wang, XJ; Warren, BS1
Klein, B; Parant, MR; Vial, H1
García-Sáinz, JA; Hong, E; Ransanz, V; Torres-Márquez, ME; Villalobos-Molina, R1
Cronin, MJ; Perkins, SN; Summers, ST1
Hall, RE; Leftwich, JA1
Chida, K; Kato, N; Kuroki, T1
Pines, M; Santora, A; Spiegel, A1
Macdonald, RL; Werz, MA1
Boonstra, J; de Laat, SW; Ponec, M; Snoek, GT1
Brunden, KR; Poduslo, JF1
Chambaut-Guerin, AM; Thomopoulos, P1
Lebenthal, E; Lee, PC; Shimizu, K1
Emoto, T; Hiraiwa, M; Kasai, K; Shimoda, S1
Dale, MM; Hirst, SJ; Obianime, AW1
Obie, JF; Putney, JW; Sugiya, H1
Goto, Y; Sugamura, K; Takeshita, T1
Akai, H; Larner, AC1
Prives, J; Rapuano, M; Ross, AF1
Alonso, M; Cárdenas, L; Carrera, AC; de Landázuri, MO; Sánchez-Madrid, F; Tugores, A1
Billah, MM; Egan, RW; Mullmann, TJ; Pai, JK; Siegel, MI1
Judd, AM; Login, IS; MacLeod, RM1
Hartzell, P; Jondal, M; McConkey, DJ; Orrenius, S1
Anderson, WB; Gopalakrishna, R1
Kitajima, Y; Sheu, HM; Yaoita, H1
Chuang, DM; Dillon-Carter, O1
Cabot, MC; Cao, HT; Welsh, CJ; Zhang, ZC1
Ailhaud, G; Gaillard, D; Lagarde, M; Négrel, R1
Gillies, RJ; Hoyer, PB; Martinez, R; Sneider, JM1
Baur, U; Bühler, FR; Bürgin, M; Resink, TJ; Scott-Burden, T1
Badwey, JA; Curnutte, JT; Heyworth, PG; Robinson, JM1
Duddy, SK; Flodström, S; Hemming, H; Kass, GE; Wärngård, L1
Hagiwara, M; Hiai, H; Hidaka, H; Ito, M; Nishizuka, Y; Nunoki, K; Ohkubo, S; Ohta, H; Onoda, K; Tanaka, T1
Bazzi, MD; Nelsestuen, GL1
Folks, TM; Griffin, GE; Kunkel, S; Leung, K; Nabel, GJ1
Alexander, RW; Griendling, KK; Tsuda, T1
Conn, PM; McArdle, CA1
Long, MW1
Spiegel, S1
Fuller, SJ; Sugden, PH1
Inoue, Y; Rebois, RV1
Asou, H; Ikarashi, Y; Itoh, K; Maruyama, Y1
Aboolian, A; Nord, EP; Vander Molen, M1
Gautron, J; Martelly, I; Moraczewski, J1
Mauduit, P; Rossignol, B; Zoukhri, D1
Akerman, KE; Heikkilä, J1
Apovo, M; Beuzard, Y; Gascard, P; Giraud, F; Rhoda, MD1
Deaciuc, IV; Hermiller, JB; Mehegan, JP; Rodriguez de Turco, EB; Roth, BL; Spitzer, JA1
Alcantara, O; Boldt, DH; Denham, CA; Phillips, JL1
Alesse, E; Di Eugenio, R; Grazia Cifone, M; Morrone, S; Paolini, R; Procopio, A; Santoni, A; Santoni, G1
Flores-Romo, L; Foster, D; Gordon, J; Guy, GR1
Gárdos, G; Görög, G; Sarkadi, B; Tordai, A1
Malik, KU; Sehic, E1
Grove, DS; Mastro, AM1
Conn, PM; Huckle, WR; McArdle, CA1
Benedict, SH; Gelfand, EW; Lau, A; Mills, GB; Petsche, D; Schaffer, FM; Williams, BR1
Cronin, MJ; Sando, JJ; Summers, ST; Walker, JM1
Huhtaniemi, I; Nikula, H1
Fukumoto, Y; Hamamori, Y; Takai, Y; Tsuda, T; Yamashita, T1
Hirata, Y1
Akita, H; Fukuzaki, H; Go, M; Yokoyama, M1
Downer, RG; Gole, JW; Gupta, J; Orr, GL1
Allgaier, C; Hertting, G1
Araki, S; Fukuzaki, H; Kariya, K; Kawahara, Y; Takai, Y1
Fredholm, BB; Kvanta, A; Nordstedt, C1
Berlingieri, MT; Chiosi, E; Fusco, A; Grieco, M; Illiano, G; Spina, A1
Fondacaro, JD1
Jones, MJ; Murray, AW1
Cronin, MJ; Hewlett, EL; Sortino, MA; Summers, ST1
Janowsky, A; Labarca, R; Paul, SM1
Blumberg, PM; Herald, CL; Pettit, GR; Sako, T; Yuspa, SH1
Canonico, PL; Catania, MV; Favit, A; Nicoletti, F1
Andersson, T; Fällman, M; Stendahl, O1
Bauer, KD; Dunn, MM; Kamp, DW; Rubin, DB1
Bolard, J; Castagna, M; Frézard, F; Garnier-Suillerot, A1
Adams, JC; Gullick, WJ1
Chuang, LF; Chuang, RY; Israel, M; Zhao, FK1
Hurley, DJ; Mastro, AM1
Drummond, AH; MacIntyre, DE; McNicol, A1
Bell, RM; Czech, MP; Davis, RJ; Ganong, BR1
Civan, MM; Mauro, T; O'Brien, TG; Rubenstein, D1
Benveniste, R; Ilekis, J1
Patel, J; Rebois, RV1
Madshus, IH; Olsnes, S; Sandvig, K1
Fukuzaki, H; Kaibuchi, K; Kawahara, Y; Takai, Y; Tsuda, T1
Strnad, CF; Wong, K1
Chuang, DM1
Hamamori, Y; Kaibuchi, K; Kikuchi, A; Kozawa, O; Takai, Y1
Gainer, HS; Murray, AW1
Jetten, AM; Shirley, JE1
Bell, RM; Lambeth, JD; Merrill, AH; Olcott, MC; Wilson, E1
Adams, DO; Hamilton, TA; Johnston, PA1
Ginsberg, J; Murray, PG1
Beatty, PG; Gahmberg, CG; Nilsson, K; Patarroyo, M1
Enna, SJ; Karbon, EW; Shenolikar, S1
Ferber, E; Flesch, I1
Bonser, RW; Dawson, J; Garland, LG; Hodson, HF; Thompson, NT1
el-Fakahany, EE; Lai, WS1
Fishman, PH; Patel, J; Sullivan, M1
Cech, P; Cohen, LE; Lehrer, RI; Szklarek, D1
Kanno, Y; Sasaki, Y; Sastrodihardjo, S; Shiba, Y1
Acero, R; Erroi, A; Ghezzi, P; Mantovani, A; Salmona, M1
Cheng, YC; Grill, SP; Li, JS; Nutter, LM; Tan, RS1
Blumberg, PM; Bressler, JP; Frost, MM; Leach, KL1
Hamamori, Y; Nishimura, N; Takai, Y; Tsuda, T; Yamamoto, T1
Kaibuchi, K; Kikuchi, A; Takai, Y; Tanimoto, T; Tsuda, T; Yamashita, T1
Hunter, DD; Liles, WC; Meier, KE; Nathanson, NM1
Cavender, D; Haskard, D; Ziff, M1
Gerthoffer, WT1
Czech, MP; Davis, RJ1
Demers, LM; Veldhuis, JD1
Chadarevian, A; Pellegrini, M; Yamamoto, K1
Fink, G; Johnson, MS; Mitchell, R1
Hogans, BB; Spivak, JL1
Liskamp, RM; O'Brian, CA; Solomon, DH; Weinstein, IB1
Häring, HU; Kirsch, D; Obermaier, B1
Brown, EJ; Frank, MM; Gaither, TA; O'Shea, JJ; Takahashi, T1
Fernyhough, P; Hall, FL; Ishii, DN; Vulliet, PR1
Lytton, FD; Mitchell, MD1
Bell, RM; Davis, RJ; Faucher, M; Gironès, N; Hannun, YA1
Forsbeck, K; Ingelman-Sundberg, M; Nilsson, K; Patarroyo, M; Skoglund, G1
Allard, LR; Beinfeld, MC1
Anderson, D; Dewdney, RS; Soper, CJ1
Bogdanovic, RP; Brandes, LJ; Gerrard, JM; LaBella, FS; Lint, DW; Reid, RE1
Bennett, JL; Blair, KL; Pax, RA2
DiCorleto, PE; Uratsuji, Y1
Horiuchi, T; Kusaba, T; Mayumi, T; Nagasawa, K1
Consalvey, SD; Dexter, TM; Downes, CP; Huang, SJ; Monk, PN; Whetton, AD1
Bijsterbosch, MK; Holman, M; Klaus, GG; McLaughlin, JB1
Fujii, M; Goto, Y; Hinuma, Y; Iwami, M; Nakamura, M; Sugamura, K; Takeshita, T1
Bertrand, J; Capeau, J; Caron, M; Cherqui, G; Picard, J; Wicek, D1
Del Vecchio, PJ; Gudewicz, PW; Odekon, LE; Saba, TM1
Niedel, JE; Salehi, Z; Taylor, JD1
Barsky, SH; Gopalakrishna, R1
de Laat, SW; Mummery, CL; Snoek, GT; van den Brink, CE; van der Saag, PT1
Bayard, F; Darbon, JM; Valette, A1
Bell, RM; Hannun, YA; Kinkade, JM; Merrill, AH; Sereni, AM; Stevens, VL1
Balazovich, KJ; Boxer, LA; Smolen, JE1
Chatterjee, M; Tejada, M1
Hawkins, DJ; Miller, JR; Wells, JN1
Mullin, JM; O'Brien, TG1
Anderson, WB; Barsky, SH; Gopalakrishna, R; Thomas, TP1
Pettit, GR; Ramsdell, JS; Tashjian, AH1
Fukuzaki, H; Kariya, KI; Kawahara, Y; Takai, Y; Tsuda, T1
Hirning, LD; Matthies, HJ; Miller, RJ; Palfrey, HC1
Veldhuis, JD; Wheeler, MB1
Chobanian, MC; Hammerman, MR1
Aitken, A; Ellis, CA; Qureshi, N; Takayama, K1
Kariya, K; Takai, Y1
Hoult, JR; Nourshargh, S1
Bayard, F; Clamens, S; Darbon, JM; Oury, F1
Atherton, SE; Sando, JJ; Speizer, LA1
Abraham, I; Burnett, BA; Groppi, VE; Leach, KL; Mayo, JK; Powers, EA1
Dale, MM; Obianime, AW1
Fisher, GJ; Harris, VA; Voorhees, JJ1
Kolesnick, RN1
Cobbold, PH; Cuthbertson, KS; Woods, NM1
Blumberg, PM; Sharkey, NA1
McCulley, DE; Russell, JH; Taylor, AS1
Borner, C; Conscience, JF; Eppenberger, U; Erne, P; Fabbro, D; Mazurek, N; Regazzi, R; Wyss, R1
Fukumoto, Y; Fukuzaki, H; Kariya, K; Kawahara, Y; Takai, Y; Tsuda, T; Yamamoto, T1
de Groot, PG; Reinders, JH; van Mourik, JA; Vervoorn, RC; Verweij, CL1
Gordon, J; Guy, GR; Ledbetter, JA; Millsum, MJ1
Meldolesi, J; Pandiella, A; Vicentini, LM1
Gavin, JR; Hammerman, MR; Morrissey, JJ; Rogers, S1
Parker, PJ; Rodriguez-Pena, A; Rozengurt, E; Stabel, S; Young, S1
Tauber, AI1
Baylin, SB; Berger, CL; de Bustros, A; Leong, SS; Nelkin, BD; Roos, BA1
Aguelon-Pegouries, AM; Enomoto, T; Furstenberger, G; Marks, F; Martel, N; Yamasaki, H1
Gescher, A; Reed, DJ1
Bressler, JP; Kornblith, PL; Weingarten, D1
Degen, JL; Estensen, RD; Nagamine, Y; Reich, E1
Arcoleo, JP; Brothman, AR; Liskamp, RM; Miller, OJ; Weinstein, IB1
Stedman, DB; Welsch, F1
Finlay, TH; Kadner, SS; Katz, J; Levitz, M1
Chen, BD; Wilkins, KL1
Lefkowitz, RJ; Nambi, P; Sibley, DR1
Pettit, GR; Smith, JB; Smith, L1
Malcolm, AR; McKenna, EJ; Mills, LJ1
Carchman, RA; Lane, RW; Smith, BM; Sturm, RJ1
Adams, DO; Hamilton, TA; Rigsbee, JE; Scott, WA1
Blumberg, PM; Jeng, AY; Lichti, U; Strickland, JE1
Enomoto, T; Kanno, Y; Martel, N; Yamasaki, H1
Arcoleo, J; Backer, J; Gattoni-Celli, S; Hsiao, WL; Jeffrey, A; Kirschmeier, P; Okin, E; Weinstein, IB1
Blumberg, PM; Chritton, S; Lew, KK1
Enomoto, T; Kanno, Y; Martel, N; Shiba, Y; Yamasaki, H1
Kaibuchi, K; Kikkawa, U; Miyake, R; Nishizuka, Y; Tanaka, Y; Tsuda, T1
Dicker, P; Rozengurt, E1
Salomon, DS1
De Larco, JE; Shoyab, M; Todaro, GJ1
Dulbecco, R; Okada, S; Sonnenberg, A1
Jaken, S; Phillips, MA1
Fürstenberger, G; Marks, F; Sachs, L; Simantov, R1
Eisinger, M; Greenebaum, E; Nicolaides, M; Vogel, RH; Weinstein, IB1
Chang, J1
Colburn, NH; Dalal, B; Gindhart, TD; Hegamyer, GA1
Collins, M; McKay, I; Rozengurt, E; Taylor-Papadimitriou, J1
Chen, BD; Hsu, S; Lin, HS1
Carchman, RA; Harris, LS; Lane, RW; Laskin, DL; Smith, BM; Sturm, RJ1
Misukonis, MA; Weinberg, JB1
Fox, CF; Iwashita, S1
Kuhn, LJ; Niedel, JE; Vandenbark, GR1
Pastan, I; Werth, DK1
Craigmyle, LS; Licht, MR; Silverstein, SC; Wright, SD1
Besterman, JM; Cuatrecasas, P1
Estensen, RD; Mascioli, DW1
Isakson, PC; Simpson, L1
Peterfreund, RA; Vale, WW1
Baba, Y; Fujita, T; Ito, Y; Kobayashi, N; Matsuda, S; Morikawa, S; Nakao, Y; Saida, T; Watanabe, S1
Chida, K; Kuroki, T1
Anderson, NL; Callaham, MF; Gemmell, MA; Huberman, E; Murao, S1
Burczak, JD; Fairley, JL; Moskal, JR; Sweeley, CC; Trosko, JE1
Gahmberg, CG; Patarroyo, M1
Schorderet-Slatkine, S; Urner, F1
Janowsky, A; Labarca, R; Patel, J; Paul, SM1
Honikman-Leban, E; Moulé, Y1
Dawson, G; Golomb, HM; Lockney, MW1
Blumberg, PM; Jaken, S; Shupnik, MA; Tashjian, AH1
Bejarano, MT; Klein, E; Masucci, MG; Ramos, OF1
Hoffman, DR; Huberman, E1
Callaham, M; Huberman, E; Slaga, TJ; Solanki, V1
Cogan, U; Fisher, PB; Horowitz, AD; Schachter, D; Weinstein, IB1
Blumberg, PM; Butler-Gralla, E; Herschman, HR1
Callaham, M; Huberman, E; Slaga, T; Solanki, V; Weeks, C1
Guy, GR; Murray, AW1
Drevon, C; Martel, N; Yamasaki, H1
Farrar, JJ; Hilfiker, ML; Salomon, DS; Sando, JJ1
Blumberg, PM; Delclos, KB; Dunphy, WG; Jaken, S1
de Prost, D; Hakim, J; Khechai, F; Ollivier, V; Ramani, M; Ternisien, C; Vu, T1
Altman, A; Baier, G; Baier-Bitterlich, G; Bonnefoy-Berard, N; Burn, P; Coggeshall, KM; Gulbins, E; Langlet, C; Telford, D; Wittinghofer, A1
Mühl, H; Pfeilschifter, J1
Cano, C; Malik, KU; Slavik, KJ1
Nakamura, S; Nishizuka, Y; Ogita, K; Yamaguchi, K1
Fukao, M; Hattori, Y; Kanno, M; Kawasaki, H1
Arkhammar, P; Berggren, PO; Bertorello, AM; Efendić, S; Zaitsev, SV1
Snutch, TP; Soong, TW; Stea, A1
Mosior, M; Newton, AC1
Satoh, H2
Amon, U; Ramachers, U; von Stebut, E; Wolff, HH1
Daniel, EE; Kwan, CY; Shimamoto, H; Shimamoto, Y1
Haist, JV; Karmazyn, M1
Moallem, E; Naveh-Many, T; Silver, J1
Furukawa, Y; Kim, HN; Kubo, T1
Boulla, G; Gourdji, D; Passegue, E; Richard, JL1
Kunz, SS; Miller, KR; Wiest, PM1
Aharon, A; Kraiem, Z; Sadeh, O; Yosef, M1
Pan, M; Stevens, BR1
Akompong, T; Schonhorn, JE; Wessling-Resnick, M1
Godson, C; Li, SL; Prentki, M; Roche, E; Schlegel, W; Zhao, SJ1
Brunello, N; Perez, J; Racagni, G; Rovescalli, AC; Steardo, L; Vitali, S1
Cross, KM; Dunning, PM; Garland, CJ; Murphy, TV1
Schwartz, JH; Sossin, WS1
Smith, RD1
Hundle, B; Messing, RO; Roivainen, R1
Anderson, WB; Lehel, C; Mischak, H; Mushinski, JF; Olah, Z1
Chaki, S; Muramatsu, M; Otomo, S1
Hirano, T; Kitajima, K; Oda, T; Shimizu, N; Utiyama, H1
Brooks, G; East, JA; Goss, MW; Hart, IR1
Martin, J; Meenakshi, T; Ross, FP; Teitelbaum, SL1
Awtrey, CS; Hecht, G; Madara, JL; Matthews, JB; Tally, KJ; Thompson, RS1
Kuo, ML; Lee, KC; Lin, JK; Wu, WS1
Darcy, KM; Guan, X; Ip, MM; Wada, T1
Bazan, E; Campbell, AK; Rapoport, RM1
Fragio, C; Roldan, ER1
Bond, J; Dawson, T; Eccles, N; Wynford-Thomas, D1
Colucci, WS; Izzo, NJ; Tulenko, TN1
Fujishima, M; Hirata, M; Kosaka, C; Masuda, J; Ogata, J; Sasaguri, T; Shimokado, K1
Bean, BP; Lovinger, DM; Merritt, A; Swartz, KJ1
Fantus, IG; Nower, P; Schwartz, T; Torossian, K1
Cooper, DM; Yoshimura, M1
Hangai, K; Karibe, A; Keitoku, M; Takishima, T; Watanabe, J1
Detimary, P; Gao, ZY; Gembal, M; Gilon, P; Henquin, JC1
Rossignol, B; Sergheraert, C; Zoukhri, D1
McCabe, MJ; Orrenius, S1
Huber, G; Löffler, J1
Ching, KN; Nicholson, WE; Orth, DN; Won, JG1
Ashby, CR; Edwards, E; Wang, RY1
Nakano, R; Shimamoto, T; Yamoto, M1
Bullock, WW; Creamer, HR; Gabler, WL1
Celis, JE; Rasmussen, HH1
Craven, PA; DeRubertis, FR; Studer, RK1
Autrup, H; Christensen, B; Kieler, J; Skouv, J1
Hansen, H; Parissenti, AM; Riedel, H; Shieh, HL; Su, L1
Fredholm, BB; Lerner, UH; Ljunggren, O; Ljunghall, S; Nordstedt, C1
Chambers, TC; Chiou, SH; Kuo, JF; Raynor, RL; Zheng, B1
Kitamura, Y; Miyazaki, A; Nomura, Y1
Kruger, H; Shanley, BC; Wilce, PA1
Erusalimsky, JD; Hong, Y; Martin, JF; Vainchenker, W1
Birch, KA; Dell, C; Heath, WF; Hermeling, RN; Johnston, CM; Reifel-Miller, A; Smith, C; Stramm, L; Williamson, JR1
Benz, D; Möller, K; Perrin, D; Söling, HD1
Groen, AK; Klinkspoor, JH; Lee, SP; Tytgat, GN1
Galea-Lauri, J; Katz, DR; Latchman, DS1
Gong, MC; Jensen, PE; Somlyo, AP; Somlyo, AV1
Mills, J; Reiner, PB1
Kotsonis, P; Majewski, H1
Hori, M; Ikuhara, T; Isogai, Y; Matsuzaki, K; Nakamura, I; Suda, T; Suzuki, H; Takahashi, N1
Gaudette, GR; Kirvaitis, RJ; Krukenkamp, IB; Levitsky, S; Miyatake, T1
Boneh, A; Turgeman, D1
Kan, H; Malik, KU; Ruan, Y1
Bevan, JA; Laher, I; Xie, H1
Ball, SG; Goodall, AR; Turner, NA; Vaughan, PF; Walker, JH1
Acs, P; Blumberg, PM; Giese, T; Goodnight, J; Mischak, H; Mushinski, JF; Wang, QJ1
Haak, LL; Heller, HC; van den Pol, AN1
Bellamy, F; Nicolas, V; Riffaud, JP; Yablonsky, F1
Hsu, MF; Lin, CN; Raung, SL; Tsao, LT; Wang, JP1
Fu, WM; Lee, KF; Tang, YB1
Matthews, SA; Pettit, GR; Rozengurt, E1
Daniele, E; Lograno, MD; Villani, G1
Linde, C; Löffler, C; Quast, U1
Chelliah, J; Freemerman, AJ; Grant, S; Jarvis, WD; Wu-Pong, S1
Lin, CN; Raung, SL; Tsao, LT; Wang, JP1
Almazan, G; Larocca, JN1
Dent, G; Leff, AR; Magnussen, H; Muñoz, NM; Rabe, KF; Rühlmann, E; Zhu, X1
Han, Z; Patil, RV; Wax, MB1
Cox, A; Findlay, JB; Law, NM1
Locniskar, MF; Mouat, MF1
Garzaro, D; Kalvatchev, Z; Walder, R1
Compton, MM; Waldrip, HM1
Cubillos, S; Lima, L1
Ciereszko, RE; Guan, Z; Ottobre, AC; Ottobre, JS; Petroff, BK; Stokes, BT1
Groen, AK; Klinkspoor, JH; Lee, SP; Mok, KS; Tytgat, GN; Van Klinken, BJ1
Ezumi, Y; Takayama, H; Uchiyama, T1
Bełtowski, J; Górny, D; Marciniak, A1
Emiliozzi, C; Mograbi, B; Rochet, N; Rossi, B1
Dugué, B; Titievsky, A; Törnquist, K; Tuominen, R; Vainio, P1
Dessauer, CW; Hume, JR; Keef, KD; Zhong, J1
Walaas, SI1
Borowski, P; Kühl, R; Laufs, R; Medem, S; Roloff, S1
Alvarez, LJ; Candia, OA; Turner, HC; Zamudio, AC1
Belury, MA; Nickel, KP1
Dietz, R; Haller, H; Li, PF; Maasch, C; von Harsdorf, R1
Barbazuk, SM; Gold, MR1
Ford, BD; Ivy, MT; Mtshali, CP; Townsel, JG1
Kobayashi, H; Nakayama, T; Takami, Y; Wada, A; Yamamoto, R; Yanagita, T; Yokoo, H; Yuhi, T1
Iannazzo, L; Kotsonis, P; Majewski, H; Murphy, TV; Prountzos, C1
Inoue, T; Koono, M; Nabeshima, K; Shimao, Y1
Bienfait, B; Blumberg, PM; Fang, TW; Fenick, D; Garfield, S; Marquez, VE; Wang, QJ1
Oleskevich, S; Walmsley, B1
Checler, F; Frobert, Y; Grassi, J; Lehmann, S; Paitel, E; Vincent, B1
Brown, PD; Kajita, H; Whitwell, C1
Dartt, DA; Hodges, RR; Kanno, H; Ralda, N; Rawe, IM; Rios, JD; Rios, JR; Zieske, JD; Zoukhri, D1
Franceschi, RT; McCauley, LK; Ouyang, H; Somerman, MJ; Wang, D1
Asghar, M; Hussain, T; Lokhandwala, MF1
Charli, JL; Cisneros, M; Joseph-Bravo, P; Vargas, MA1
Checler, F; Creemers, J; Frank, SJ; Lopez-Perez, E; Seidah, N; Zhang, Y1
Ahmed, IS; Alderton, F; Darroch, P; McKie, A; Pyne, N; Pyne, S; Sambi, B1
Fujitani, K; Fukazawa, Y; Fukuda, T; Inokuchi, K; Isojima, Y; Kato, A; Sugiyama, H1
Balla, Z; Edes, I; Ferdinandy, P; Flameng, W; Mubagwa, K; Pongo, E; Szilvassy, Z1
Blumberg, PM; Fujii, T; Garcia-Bermejo, ML; Han, KC; Kazanietz, MG; Kuroki, T; Lee, J; Leskow, FC; Marquez, VE; Ohba, M; Wang, Q1
Chung, KH; Gye, MH; Shin, HJ; Yoo, BS1
Clark, JH; Glazer, RI; Haridasse, V1
Ciereszko, RE; Dusza, L; Kaminska, B; Opalka, M1
Iijima, T; Satoh, E; Xu, F1
Griese, A; Iakubov, R; Mischak, H; Riepenhausen, G; Schaefer, M; Schnell, S; Schöfl, C1
Korf, HW; Laedtke, E; Schomerus, C1
Bełtowski, J; Borkowska, E; Jamroz-Wiśniewska, A; Marciniak, A; Wójcicka, G1
Blumberg, PM; Braun, DC; Cao, Y; Garfield, SH; Hur, GM; Wang, S1
Anderson, G; Chen, J; Wang, QJ1
Basu, A; Huang, J; Mohanty, S1
Illsley, NP; You, G; Zhou, F1
Isacke, CM; Thorne, RF; Tzircotis, G1
Bond, JA; Errington, R; Gescher, AJ; Lemoine, NR; Smith, PJ; Verschoyle, RD; Wiltshire, M; Wynford-Thomas, D1
Förstermann, U; Goettsch, C; Horke, S; Li, H; Morawietz, H; Xia, N; Xu, H1
Anderson, SJ; Bashari, E; Benos, DJ; Fuller, CM; Kapoor, N; Meltzer, RH; Qadri, YJ; Zhou, ZH1
Arttamangkul, S; Birdsong, W; Williams, JT1
Boydens, C; Pauwels, B; Van de Voorde, J; Vanden Daele, L1

Reviews

5 review(s) available for phorbol 12,13-dibutyrate and tetradecanoylphorbol acetate

ArticleYear
Intestinal ion transport and diarrheal disease.
    The American journal of physiology, 1986, Volume: 250, Issue:1 Pt 1

    Topics: Acid-Base Equilibrium; Adrenergic alpha-Agonists; Animals; Arachidonic Acids; Carbachol; Chlorides; Cholera Toxin; Cyclic AMP; Cyclic GMP; Diarrhea; Electric Stimulation; Electrolytes; Hydroxyeicosatetraenoic Acids; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Leukotrienes; Models, Biological; Narcotics; Phenothiazines; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Protein Kinase C; Receptors, Cholinergic; Receptors, Muscarinic; Renin-Angiotensin System; Sodium; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate

1986
Protein kinase C and the activation of the human neutrophil NADPH-oxidase.
    Blood, 1987, Volume: 69, Issue:3

    Topics: Arachidonic Acids; Caenorhabditis elegans Proteins; Calcium; Carrier Proteins; Diglycerides; Enzyme Activation; Membrane Proteins; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate

1987
Molecular mechanisms of tumor promotion and multistage carcinogenesis.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Adenosine Triphosphate; Animals; Base Sequence; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Transformation, Neoplastic; ErbB Receptors; Humans; Lyngbya Toxins; Molecular Conformation; Neoplasms; Oncogenes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Receptors, Drug; Receptors, Immunologic; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1983
Epidermal growth factor receptors interact with transforming growth factors produced by certain human tumor cells and are distinct from specific membrane receptors for phorbol and ingenol esters.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; ErbB Receptors; Humans; Neoplasms; Peptides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transforming Growth Factors

1982
Specific binding of phorbol ester tumor promoters to mouse tissues and cultured cells.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Biological Evolution; Brain; Caenorhabditis elegans Proteins; Calcium; Carcinogens; Carrier Proteins; Cell Membrane; Cells, Cultured; Humans; Kinetics; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Drug; Skin; Spleen; Structure-Activity Relationship; Temperature; Tetradecanoylphorbol Acetate; Thermodynamics

1982

Other Studies

505 other study(ies) available for phorbol 12,13-dibutyrate and tetradecanoylphorbol acetate

ArticleYear
Role of the phenolic hydroxyl group in the biological activities of simplified analogue of aplysiatoxin with antiproliferative activity.
    Bioorganic & medicinal chemistry letters, 2010, Oct-15, Volume: 20, Issue:20

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Hydroxyl Radical; Lyngbya Toxins; Neoplasms; Protein Kinase C

2010
Generation of 'Unnatural Natural Product' library and identification of a small molecule inhibitor of XIAP.
    Bioorganic & medicinal chemistry, 2011, Jul-15, Volume: 19, Issue:14

    Topics: Antineoplastic Agents; Apoptosis; Biological Products; Caspase 3; Caspase Inhibitors; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Activation; HeLa Cells; Humans; Imides; Indole Alkaloids; Lyngbya Toxins; Magnetic Resonance Spectroscopy; Molecular Structure; Protein Binding; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship; X-Linked Inhibitor of Apoptosis Protein

2011
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP.
    Bioorganic & medicinal chemistry, 2014, Jun-15, Volume: 22, Issue:12

    Topics: Animals; Cell Membrane; Cells, Cultured; CHO Cells; Cricetulus; Diglycerides; DNA-Binding Proteins; Fluorescence Polarization; Fluorescence Resonance Energy Transfer; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Indoles; Lactones; Male; Models, Molecular; Prostatic Neoplasms; Protein Isoforms; Protein Kinase C

2014
Antiviral Activity of Diterpene Esters on Chikungunya Virus and HIV Replication.
    Journal of natural products, 2015, Jun-26, Volume: 78, Issue:6

    Topics: Anti-HIV Agents; Antiviral Agents; Chikungunya virus; Diterpenes; DNA Replication; Esters; Euphorbiaceae; HIV Infections; HIV-1; HIV-2; Molecular Structure; Phorbol Esters; Tetradecanoylphorbol Acetate; Virus Replication

2015
Phorbol esters induce nitric oxide synthase activity in rat hepatocytes. Antagonism with the induction elicited by lipopolysaccharide.
    The Journal of biological chemistry, 1992, Dec-15, Volume: 267, Issue:35

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carcinogens; Cells, Cultured; Cyclic GMP; Diglycerides; Enzyme Induction; Kinetics; Lipopolysaccharides; Liver; Nitric Oxide Synthase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Tetradecanoylphorbol Acetate

1992
Purification and characterization of protein kinase C from the nematode Caenorhabditis elegans.
    The Biochemical journal, 1992, Feb-15, Volume: 282 ( Pt 1)

    Topics: Animals; Caenorhabditis; Calcium Chloride; Chromatography; Chromatography, Affinity; Chromatography, Ion Exchange; Diglycerides; Durapatite; Hydroxyapatites; Kinetics; Molecular Weight; Phorbol 12,13-Dibutyrate; Protein Kinase C; Substrate Specificity; Tetradecanoylphorbol Acetate

1992
Inhibition of human neutrophil protein kinase C activity by the antimalarial drug mefloquine.
    Biochemical pharmacology, 1992, Feb-04, Volume: 43, Issue:3

    Topics: Dose-Response Relationship, Drug; Humans; Kinetics; Mefloquine; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate

1992
A phorbol diester resistant monocytic leukemia cell line is PKC deficient.
    International journal of cell cloning, 1992, Volume: 10, Issue:1

    Topics: Animals; Blotting, Northern; Blotting, Western; Cell Division; Drug Resistance; Leukemia, Monocytic, Acute; Phorbol 12,13-Dibutyrate; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Rats; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1992
Phorbol esters inhibit ionomycin-induced hydrolysis of phosphoinositides and phosphatidylcholine in bovine corneal epithelial cells.
    Current eye research, 1992, Volume: 11, Issue:2

    Topics: Animals; Cattle; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cornea; Enzyme Activation; Epithelium; Hydrolysis; Ionomycin; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases

1992
Protein kinase C has both stimulatory and suppressive effects on macrophage superoxide production.
    Journal of cellular physiology, 1992, Volume: 152, Issue:1

    Topics: Alkaloids; Animals; Biological Transport; Bone Marrow Cells; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Endotoxins; Granulocyte-Macrophage Colony-Stimulating Factor; Inositol Phosphates; Iodine Radioisotopes; Macrophages; Mice; Mice, Inbred CBA; Phorbol 12,13-Dibutyrate; Protein Kinase C; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha; Zymosan

1992
Modulation of luteinizing hormone-stimulated inositol phosphate accumulation by phorbol esters in bovine luteal cells.
    Endocrinology, 1992, Volume: 131, Issue:2

    Topics: Animals; Calcium; Cattle; Cyclic AMP; Dinoprost; Female; Inositol; Inositol Phosphates; Kinetics; Luteal Cells; Luteinizing Hormone; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Pregnancy; Progesterone; Sodium Fluoride; Tetradecanoylphorbol Acetate; Type C Phospholipases

1992
Differentiation of renal Na(+)-K(+)-ATPase in control and streptozotocin-induced diabetic mice by G-protein acting toxins and phorbol esters.
    European journal of pharmacology, 1992, Apr-10, Volume: 225, Issue:4

    Topics: Adenylate Cyclase Toxin; Animals; Bucladesine; Cholera Toxin; Diabetes Mellitus, Experimental; Enzyme Activation; Kidney Cortex; Kidney Medulla; Male; Mice; Mice, Inbred ICR; Nicardipine; Ouabain; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1992
Defective stimulus-response coupling in human monocytes infected with Leishmania donovani is associated with altered activation and translocation of protein kinase C.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Aug-15, Volume: 89, Issue:16

    Topics: Animals; Blotting, Western; Caenorhabditis elegans Proteins; Carrier Proteins; Diglycerides; Enzyme Activation; Humans; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Leishmania donovani; Monocytes; Oxygen Consumption; Phorbol 12,13-Dibutyrate; Phosphates; Phosphoproteins; Protein Kinase C; Receptors, Drug; Superoxides; Tetradecanoylphorbol Acetate

1992
Protein kinase C regulation of cardiac calcium channels expressed in Xenopus oocytes.
    Pflugers Archiv : European journal of physiology, 1992, Volume: 421, Issue:2-3

    Topics: Animals; Calcium Channels; Cyclic AMP; Diglycerides; Down-Regulation; Electrophysiology; Enzyme Activation; Myocardium; Oocytes; Phorbol 12,13-Dibutyrate; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Xenopus

1992
Phorbol ester and atrial natriuretic peptide receptor response on vascular smooth muscle.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Atrial Natriuretic Factor; Cyclic GMP; Dose-Response Relationship, Drug; Down-Regulation; Guanylate Cyclase; Isoquinolines; Muscle, Smooth, Vascular; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Tetradecanoylphorbol Acetate

1992
Activation of protein kinase C by phorbol esters and arachidonic acid required for the optimal potentiation of glutamate exocytosis.
    Journal of neurochemistry, 1992, Volume: 59, Issue:4

    Topics: 4-Aminopyridine; Animals; Arachidonic Acid; Cell Membrane; Drug Synergism; Electrophysiology; Enzyme Activation; Exocytosis; Glutamates; Glutamic Acid; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate

1992
Induction of ICAM-1 by TNF-alpha, IL-1 beta, and LPS in human endothelial cells after downregulation of PKC.
    The American journal of physiology, 1992, Volume: 263, Issue:4 Pt 1

    Topics: Cell Adhesion Molecules; Cytokines; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Lipopolysaccharides; Phorbol 12,13-Dibutyrate; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1992
The actions of phorbol esters upon isolated calcium currents of Helix aspersa neurones.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 102, Issue:2

    Topics: Animals; Calcium; Calcium Channels; Helix, Snails; Membrane Potentials; Neurons; Phorbol 12,13-Dibutyrate; Tetradecanoylphorbol Acetate

1992
Effects of cell density and phorbol esters on the expression of epidermal growth factor receptors.
    Cytotechnology, 1991, Volume: 7, Issue:2

    Topics: Cell Count; Cell Division; Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; KB Cells; Kinetics; Phorbol 12,13-Dibutyrate; Tetradecanoylphorbol Acetate

1991
Divergent effects of phorbol esters and insulin on insulin-like growth factor binding protein-1 (IGFBP-1) production and mRNA in rat H4IIE hepatoma cells.
    Biochemical and biophysical research communications, 1992, Jan-15, Volume: 182, Issue:1

    Topics: Animals; Blotting, Northern; Carrier Proteins; DNA Probes; Insulin; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Kinetics; Liver Neoplasms, Experimental; Phorbol 12,13-Dibutyrate; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Phorbol 12-myristate 13-acetate activates an electrogenic H(+)-conducting pathway in the membrane of neutrophils.
    The Biochemical journal, 1992, Feb-01, Volume: 281 ( Pt 3)

    Topics: Animals; Biological Transport; Cadmium; Cell Membrane; Cell Membrane Permeability; Chloromercuribenzoates; Hydrogen-Ion Concentration; Ion Channels; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; p-Chloromercuribenzoic Acid; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protons; Swine; Tetradecanoylphorbol Acetate; Valinomycin

1992
Differential induction of 12-O-tetradecanoylphorbol-13-acetate sequence gene expression in murine melanocytes and melanoma cells.
    Molecular carcinogenesis, 1992, Volume: 5, Issue:4

    Topics: 3T3 Cells; Animals; Blotting, Northern; Bucladesine; Cell Line, Transformed; Cells, Cultured; Cycloheximide; Gene Expression; Genes, fos; Melanocytes; Melanoma, Experimental; Mice; Molecular Weight; Phorbol 12,13-Dibutyrate; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1992
Modulation of protein kinase C-epsilon by phorbol esters in the monoblastoid U937 cell.
    Cancer research, 1992, Oct-15, Volume: 52, Issue:20

    Topics: Cell Differentiation; Enzyme Activation; Enzyme Induction; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Monocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Protein kinase C and cell proliferation in spontaneously hypertensive rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1992, Volume: 14, Issue:5

    Topics: Animals; Aorta; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Hypertension; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetradecanoylphorbol Acetate; Thymidine

1992
Differential irreversible insertion of protein kinase C into phospholipid vesicles by phorbol esters and related activators.
    The Journal of biological chemistry, 1992, Oct-15, Volume: 267, Issue:29

    Topics: Animals; Binding Sites; Brain; Calcium; Enzyme Activation; Kinetics; Liposomes; Models, Structural; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phospholipids; Protein Binding; Protein Kinase C; Rats; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1992
Regulation of apical Cl- conductance and basolateral K+ conductances by phorbol esters in HT-29cl.19A cells.
    The American journal of physiology, 1992, Volume: 263, Issue:4 Pt 1

    Topics: Calcium; Carcinoma; Cell Membrane; Chlorides; Colforsin; Colonic Neoplasms; Electric Conductivity; Humans; Phorbol 12,13-Dibutyrate; Potassium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Tumor necrosis factor and interleukin-1 induce activin A gene expression in a human bone marrow stromal cell line.
    Biochemical and biophysical research communications, 1992, Oct-15, Volume: 188, Issue:1

    Topics: Activins; Blotting, Northern; Bone Marrow; Bone Marrow Cells; Cell Line; Culture Media, Conditioned; Cycloheximide; DNA; Gene Expression; Growth Substances; Humans; Inhibins; Interleukin-1; Macromolecular Substances; Phorbol 12,13-Dibutyrate; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1992
The responses to phorbol esters which stimulated protein kinase C in canine Purkinje fibers.
    General pharmacology, 1992, Volume: 23, Issue:5

    Topics: Action Potentials; Animals; Calcium; Carcinogens; Dogs; Homeostasis; Microelectrodes; Myocardial Contraction; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Purkinje Fibers; Tetradecanoylphorbol Acetate

1992
Modulation of IK,Ca by phorbol ester-mediated activation of PKC in pleural sensory neurons of Aplysia.
    Journal of neurophysiology, 1992, Volume: 68, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aplysia; Calcium; Dose-Response Relationship, Drug; Enzyme Activation; Ganglia; In Vitro Techniques; Isoquinolines; Kinetics; Membrane Potentials; Neurons, Afferent; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Piperazines; Potassium Channels; Protein Kinase C; Protein Kinase Inhibitors; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetraethylammonium Compounds

1992
Positive and negative inotropic effects of phorbol 12-myristate 13-acetate: relationship to PKC-dependence and changes in [Ca2+]i.
    Journal of molecular and cellular cardiology, 1992, Volume: 24, Issue:9

    Topics: Animals; Calcium; Enzyme Activation; Guinea Pigs; Heart; In Vitro Techniques; Intracellular Fluid; Male; Myocardial Contraction; Myocardium; Perfusion; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate

1992
Cell division arrest induced by phorbol ester in CHO cells overexpressing protein kinase C-delta subspecies.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Nov-01, Volume: 89, Issue:21

    Topics: Animals; Cell Cycle; Cell Division; CHO Cells; Cricetinae; DNA; Gene Amplification; Isoenzymes; Kinetics; Phorbol 12,13-Dibutyrate; Protein Binding; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Transfection

1992
Differential effects of phorbol esters on proliferation and calcyclin expression in human endometrial carcinoma cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1992, Volume: 3, Issue:11

    Topics: Adenocarcinoma; Alkaloids; Calcimycin; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Division; Cycloheximide; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; RNA, Messenger; RNA, Neoplasm; S100 Calcium Binding Protein A6; S100 Proteins; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Uterine Neoplasms

1992
Nonphorbol tumor promoters okadaic acid and calyculin-A induce membrane translocation of protein kinase C.
    Biochemical and biophysical research communications, 1992, Dec-15, Volume: 189, Issue:2

    Topics: Animals; Carcinogens; Cell Line; Cell Membrane; Cytosol; Ethers, Cyclic; Immunoblotting; Kidney; Kinetics; Marine Toxins; Okadaic Acid; Oxazoles; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

1992
Classical conditioning and protein kinase C activation regulate the same single potassium channel in Hermissenda crassicornis photoreceptors.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Aug-01, Volume: 89, Issue:15

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Conditioning, Classical; Enzyme Activation; In Vitro Techniques; Isoquinolines; Membrane Potentials; Phorbol 12,13-Dibutyrate; Photoreceptor Cells; Piperazines; Potassium Channels; Protein Kinase C; Snails; Tetradecanoylphorbol Acetate

1992
The protein kinase C activators, phorbol 12-myristate,13-acetate and phorbol 12,13-dibutyrate, are convulsant in the pico-nanomolar range in mice.
    European journal of pharmacology, 1992, Mar-17, Volume: 213, Issue:1

    Topics: Alkaloids; Animals; Behavior, Animal; Convulsants; Enzyme Activation; Injections, Intraventricular; Male; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Seizures; Staurosporine; Tetradecanoylphorbol Acetate

1992
Effect of phorbol esters on protein kinase C-zeta.
    The Journal of biological chemistry, 1992, Mar-05, Volume: 267, Issue:7

    Topics: Amino Acid Sequence; Blotting, Western; Cell Line; Diglycerides; Down-Regulation; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Isoenzymes; Molecular Sequence Data; Multigene Family; Phorbol 12,13-Dibutyrate; Protein Kinase C; Substrate Specificity; Tetradecanoylphorbol Acetate; Transfection

1992
Activation of human leukemia protein kinase C by tumor promoters and its inhibition by N-trifluoroacetyladriamycin-14-valerate (AD 32).
    Biochemical pharmacology, 1992, Feb-18, Volume: 43, Issue:4

    Topics: Binding, Competitive; Cell Membrane; Doxorubicin; Drug Interactions; Enzyme Activation; Humans; Kinetics; Leukemia; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Binding; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Inhibition of protein kinase C by ether-linked lipids is not correlated with their antineoplastic activity on WEHI-3B and R6X-B15 cells.
    Biochimica et biophysica acta, 1992, Feb-19, Volume: 1134, Issue:1

    Topics: Antineoplastic Agents; Cell Compartmentation; Cell Division; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Phorbol 12,13-Dibutyrate; Phospholipid Ethers; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Glucose transport by cultured human fibroblasts: regulation by phorbol esters and insulin.
    Biochimica et biophysica acta, 1992, Feb-17, Volume: 1104, Issue:1

    Topics: 3-O-Methylglucose; Biological Transport; Cells, Cultured; Cycloheximide; Dactinomycin; Fibroblasts; Humans; Insulin; Kinetics; Methylglucosides; Phorbol 12,13-Dibutyrate; Protein Synthesis Inhibitors; Tetradecanoylphorbol Acetate

1992
Pulmonary surfactant phospholipids modulate priming of rabbit alveolar macrophages for oxidative responses.
    Journal of leukocyte biology, 1992, Volume: 51, Issue:4

    Topics: Animals; Fatty Acids; Female; Glycerylphosphorylcholine; Macrophage-Activating Factors; Macrophages, Alveolar; Male; Phagocytosis; Phorbol 12,13-Dibutyrate; Phospholipids; Pulmonary Surfactants; Rabbits; Respiratory Burst; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate; Zymosan

1992
Structural requirements of lyngbyatoxin A for activation and downregulation of protein kinase C.
    Biochemistry, 1992, Apr-21, Volume: 31, Issue:15

    Topics: Animals; Blotting, Western; Cattle; Down-Regulation; Enzyme Activation; HeLa Cells; Humans; Isoenzymes; Lyngbya Toxins; Marine Toxins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1992
Actions of phorbol esters on levels of cAMP in cholera toxin-treated chief cells from guinea pig stomach.
    Biochimica et biophysica acta, 1992, Apr-30, Volume: 1135, Issue:1

    Topics: Animals; Calcimycin; Calmodulin; Carbachol; Cholera Toxin; Gastric Mucosa; Guinea Pigs; Imidazoles; In Vitro Techniques; Kinetics; Male; Phorbol 12,13-Dibutyrate; Phorbols; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate

1992
Sensitization of human cervical carcinoma cells to cis-diamminedichloroplatinum(II) by bryostatin 1.
    Cancer research, 1992, Jun-01, Volume: 52, Issue:11

    Topics: Antineoplastic Agents; Biological Transport; Bryostatins; Cell Division; Cell Line; Cisplatin; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Head and Neck Neoplasms; HeLa Cells; Humans; Isoenzymes; Kinetics; Lactones; Macrolides; Organoplatinum Compounds; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors

1992
Intracellular Ca2+ mobilization and not calcium influx promotes phorbol ester-stimulated thromboxane A2 synthesis in human platelets.
    Prostaglandins, 1992, Volume: 43, Issue:4

    Topics: Alkaloids; Blood Platelets; Calcimycin; Calcium; Chromatography, High Pressure Liquid; Cytosol; Drug Synergism; Humans; Membrane Lipids; Phorbol 12,13-Dibutyrate; Phospholipids; Platelet Aggregation; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thromboxane A2

1992
Modulation of cellular processes by H7, a non-selective inhibitor of protein kinases.
    Agents and actions, 1991, Volume: 32, Issue:3-4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Brain; CD4 Antigens; Cyclic AMP; Down-Regulation; Interleukin-2; Isoquinolines; Lymphocyte Activation; Mice; Molecular Weight; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rats; Receptors, Antigen, T-Cell; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate

1991
Studies on the mechanisms of signalling and inhibition by pertussis toxin of fibroblast growth factor-stimulated mitogenesis in Balb/c 3T3 cells.
    Cellular signalling, 1991, Volume: 3, Issue:3

    Topics: Adenylate Cyclase Toxin; Animals; Cells, Cultured; Cyclic AMP; Dexamethasone; DNA; Enzyme Activation; Fibroblast Growth Factors; Inositol Phosphates; Mice; Mice, Inbred BALB C; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1991
Activation of a heart chloride current during stimulation of protein kinase C.
    Molecular pharmacology, 1991, Volume: 40, Issue:3

    Topics: Animals; Chloride Channels; Guinea Pigs; In Vitro Techniques; Membrane Proteins; Myocardium; Norepinephrine; Phorbol 12,13-Dibutyrate; Propranolol; Protein Kinase C; Tetradecanoylphorbol Acetate

1991
Angiotensin II-induced activation of Na(+)-H+ exchange in adrenal glomerulosa cells is mediated by protein kinase C.
    Endocrinology, 1991, Volume: 129, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Carrier Proteins; Cells, Cultured; Enzyme Activation; Kinetics; Phorbol 12,13-Dibutyrate; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Zona Glomerulosa

1991
Activation of protein kinase-C inhibits vitamin D receptor gene expression.
    Molecular endocrinology (Baltimore, Md.), 1991, Volume: 5, Issue:4

    Topics: Alkaloids; Animals; Blotting, Northern; Blotting, Southern; Calcimycin; Cell Division; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Down-Regulation; Fibroblast Growth Factor 2; Gene Expression Regulation, Enzymologic; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Calcitriol; Receptors, Steroid; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate

1991
Protein kinase-C activation stimulates synthesis of gonadotropin-releasing hormone (GnRH) receptors, but does not mediate GnRH-stimulated receptor synthesis.
    Endocrinology, 1991, Volume: 129, Issue:5

    Topics: Amino Acids; Animals; Cells, Cultured; Enzyme Activation; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Cell Surface; Tetradecanoylphorbol Acetate

1991
Protein kinase C activating phorbolesters enhance the cyclic AMP response to parathyroid hormone, forskolin and choleratoxin in mouse calvarial bones and rat osteosarcoma cells.
    Bioscience reports, 1991, Volume: 11, Issue:4

    Topics: Adenylyl Cyclases; Animals; Bone and Bones; Cattle; Cholera Toxin; Colforsin; Culture Techniques; Cyclic AMP; Enzyme Activation; Mice; Osteosarcoma; Parathyroid Hormone; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
Effects of phorbol esters and pertussis toxin on calcitonin-stimulated accumulation of cyclic AMP in neonatal mouse calvarial bones.
    Calcified tissue international, 1991, Volume: 49, Issue:4

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bone Resorption; Calcitonin; Cyclic AMP; Dinoprostone; GTP-Binding Proteins; Indomethacin; Mice; Osteoclasts; Parathyroid Hormone; Peptide Fragments; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1991
Inhibition of pyroglutamyl peptidase II synthesis by phorbol ester in the Y-79 retinoblastoma cell.
    Endocrinology, 1991, Volume: 128, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Membrane; Humans; Immunoblotting; Isoquinolines; Kinetics; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Pyroglutamyl-Peptidase I; Retinoblastoma; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
Carbamylcholine and phorbol esters desensitize muscarinic receptors by different mechanisms in rat pancreatic acini.
    Pancreas, 1990, Volume: 5, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amylases; Animals; Calcimycin; Carbachol; Dose-Response Relationship, Drug; Down-Regulation; Gallic Acid; Isoquinolines; Male; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Secretory Rate; Tetradecanoylphorbol Acetate

1990
The modulatory effects of phorbol esters on histamine release from mast cells induced by a polyethylenimine and a polyallylamine.
    General pharmacology, 1990, Volume: 21, Issue:4

    Topics: Animals; Histamine Release; In Vitro Techniques; Male; Mast Cells; Molecular Weight; Phorbol 12,13-Dibutyrate; Phorbol Esters; Polyamines; Polyethyleneimine; Polyethylenes; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1990
Down-regulation of tyrosinase mRNA levels in melanoma cells by tumor promoters and by insulin.
    Molecular and cellular endocrinology, 1990, Aug-20, Volume: 72, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Enzyme Induction; Gene Expression Regulation, Neoplastic; Insulin; Melanocyte-Stimulating Hormones; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Phorbol 12,13-Dibutyrate; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Stimulation of chicken growth hormone release by phorbol esters.
    General and comparative endocrinology, 1990, Volume: 80, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Growth Hormone; Growth Hormone-Releasing Hormone; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pituitary Gland, Anterior; Protein Kinase C; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone

1990
Cytoskeletal reorganizations in human umbilical vein endothelial cells as a result of cytokine exposure.
    Experimental cell research, 1991, Volume: 196, Issue:1

    Topics: Cell Adhesion Molecules; Cell Communication; Cysteine; Cytokines; Cytoskeletal Proteins; Cytoskeleton; Endothelium, Vascular; Fluorescent Antibody Technique; Humans; Immunoblotting; Interferon-gamma; Interleukin-1; Microtubules; Phorbol 12,13-Dibutyrate; Receptors, Immunologic; Receptors, Vitronectin; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1991
Phorbol esters selectively downregulate contractile protein gene expression in terminally differentiated myotubes through transcriptional repression and message destabilization.
    The Journal of cell biology, 1991, Volume: 115, Issue:3

    Topics: Animals; Cell Differentiation; Cell Nucleus; Cells, Cultured; Chick Embryo; Contractile Proteins; DNA Probes; Kinetics; Muscles; Phorbol 12,13-Dibutyrate; Protein Kinase C; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic

1991
Effect of protein kinase C activators on the phosphorylation and the surface expression of the CDw50 leukocyte antigen.
    European journal of biochemistry, 1992, Jan-15, Volume: 203, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Antigens, CD; Antigens, Differentiation; Cell Adhesion Molecules; Concanavalin A; Cross-Linking Reagents; Diterpenes; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Flow Cytometry; Fluorescent Antibody Technique; Humans; Isoquinolines; Kinetics; Lymphocytes; Phorbol 12,13-Dibutyrate; Phosphorylation; Phytohemagglutinins; Piperazines; Precipitin Tests; Protein Kinase C; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate

1992
Chronic ethanol exposure increases levels of protein kinase C delta and epsilon and protein kinase C-mediated phosphorylation in cultured neural cells.
    The Journal of biological chemistry, 1991, Dec-05, Volume: 266, Issue:34

    Topics: Amino Acid Sequence; Animals; Antibody Specificity; Diglycerides; Enzyme Activation; Ethanol; Immunoblotting; Kinetics; Molecular Sequence Data; Neurons; PC12 Cells; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate

1991
Control of nucleoside transport in neural cells. Effect of protein kinase C activation.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adrenal Medulla; Animals; Biological Transport; Calcimycin; Caprylates; Cells, Cultured; Diglycerides; Dinucleoside Phosphates; Enzyme Activation; Ethers, Cyclic; Isoquinolines; Kinetics; Okadaic Acid; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Triglycerides

1991
Contraction of rat thoracic aorta strips by endothelin-1 in the absence of extracellular Ca2+.
    British journal of pharmacology, 1991, Volume: 104, Issue:4

    Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Endothelins; In Vitro Techniques; Indicators and Reagents; Male; Marine Toxins; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxazoles; Phorbol 12,13-Dibutyrate; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Urotensins; Vasoconstrictor Agents

1991
Phorbol binding and enzymatic activity of protein kinase C from C3H 10T1/2 cells and relation to contact inhibition.
    Folia biologica, 1991, Volume: 37, Issue:3-4

    Topics: Animals; Cells, Cultured; Contact Inhibition; Fibroblasts; Inositol Phosphates; Mice; Mice, Inbred C3H; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate

1991
Phorbol ester-induced expression of the common, low-affinity binding site for primary prostanoids in vascular smooth muscle cells.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta, Thoracic; Cells, Cultured; Enzyme Activation; Gene Expression Regulation; Isoquinolines; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1991
Response of Jurkat T cells to phorbol ester and bryostatin. Development of sublines with distinct functional responses and changes in protein kinase C activity.
    Journal of immunology (Baltimore, Md. : 1950), 1991, Nov-15, Volume: 147, Issue:10

    Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Bryostatins; CD3 Complex; Clone Cells; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Humans; In Vitro Techniques; Lactones; Lymphocyte Activation; Macrolides; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Transferrin; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
5-HT1A and histamine H1 receptors in HeLa cells stimulate phosphoinositide hydrolysis and phosphate uptake via distinct G protein pools.
    The Journal of biological chemistry, 1991, Jan-05, Volume: 266, Issue:1

    Topics: Biological Transport; Blotting, Northern; Down-Regulation; GTP-Binding Proteins; HeLa Cells; Histamine; Humans; Hydrolysis; Kinetics; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phosphates; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Pyrilamine; Receptors, Histamine H1; Receptors, Serotonin; RNA, Messenger; Serotonin; Tetradecanoylphorbol Acetate; Transfection; Virulence Factors, Bordetella

1991
Protein kinase C is not involved in alpha 1-adrenoceptor-mediated positive inotropic effect.
    The American journal of physiology, 1991, Volume: 260, Issue:1 Pt 2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Electric Conductivity; Hydrolysis; Isoquinolines; Male; Membrane Potentials; Myocardial Contraction; Papillary Muscles; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Staurosporine; Stimulation, Chemical; Tetradecanoylphorbol Acetate

1991
The role of protein kinase C activation and inositol phosphate production in the regulation of cell-surface expression of Mac-1 by complement fragment C5a.
    Biochimica et biophysica acta, 1991, Apr-17, Volume: 1092, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Cell Line; Complement C5a; Cytoplasm; Enzyme Activation; Humans; Inositol Phosphates; Isoquinolines; Kinetics; Macrophage-1 Antigen; Oxygen; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1991
Decreased respiratory burst activity in neonatal bovine neutrophils stimulated by protein kinase C agonists.
    American journal of veterinary research, 1991, Volume: 52, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Cattle; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Female; Isoquinolines; Neutrophils; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate

1991
Distinct patterns of phorbol ester-induced downregulation of protein kinase C activity in adriamycin-selected multidrug resistant and parental murine fibrosarcoma cells.
    Cancer letters, 1991, Jul-04, Volume: 58, Issue:3

    Topics: Animals; Down-Regulation; Doxorubicin; Drug Resistance; Fibrosarcoma; In Vitro Techniques; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1991
Presynaptic sites of isolated canine saphenous veins are more sensitive to protein kinase C than postsynaptic ones.
    Japanese journal of pharmacology, 1991, Volume: 56, Issue:3

    Topics: Animals; Dogs; Enzyme Activation; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Phorbol 12,13-Dibutyrate; Polymyxin B; Potassium Chloride; Protein Kinase C; Saphenous Vein; Tetradecanoylphorbol Acetate; Tritium; Vasoconstriction

1991
Inhibition of translational initiation by metalloendoprotease antagonists. Evidence for involvement of sequestered Ca2+ stores.
    The Journal of biological chemistry, 1991, Apr-15, Volume: 266, Issue:11

    Topics: Amino Acid Sequence; Animals; Calcimycin; Calcium; Carrier Proteins; Cell Line; Cycloheximide; Dactinomycin; Dipeptides; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Immunoglobulin Heavy Chains; Inositol Phosphates; Kinetics; Leucine; Leupeptins; Metalloendopeptidases; Molecular Chaperones; Molecular Sequence Data; Oligopeptides; Peptide Chain Initiation, Translational; Phorbol 12,13-Dibutyrate; RNA, Messenger; Serine Endopeptidases; Tetradecanoylphorbol Acetate

1991
Angiotensin II-induced phosphatidylcholine hydrolysis in cultured vascular smooth-muscle cells. Regulation and localization.
    The Biochemical journal, 1991, May-15, Volume: 276 ( Pt 1)

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Arsenicals; Cells, Cultured; Choline; Egtazic Acid; Hydrolysis; Kinetics; Male; Muscle, Smooth, Vascular; Myristic Acid; Myristic Acids; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Protein Kinases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1991
Possible involvement of protein kinase C in gonadotropin and growth hormone release from dispersed goldfish pituitary cells.
    General and comparative endocrinology, 1991, Volume: 81, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Diglycerides; Egtazic Acid; Enzyme Activation; Goldfish; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Growth Hormone; Isoquinolines; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Pituitary Gland; Protein Kinase C; Tetradecanoylphorbol Acetate; Verapamil

1991
Action of organic solvents on protein kinase C.
    European journal of pharmacology, 1991, Apr-25, Volume: 206, Issue:4

    Topics: Animals; Binding, Competitive; Diglycerides; Enzyme Activation; Histones; Lipid Bilayers; Male; Membrane Fluidity; Membranes, Artificial; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Phosphatidylserines; Phosphorylation; Protein Kinase C; Rats; Rats, Inbred Strains; Solvents; Tetradecanoylphorbol Acetate

1991
Induction of macrophage plasminogen activator by asbestos is independent of PKC activation.
    Archives of toxicology, 1991, Volume: 65, Issue:5

    Topics: Animals; Asbestos; Auranofin; Cells, Cultured; Down-Regulation; Enzyme Activation; Macrophages; Mice; Phorbol 12,13-Dibutyrate; Plasminogen Activators; Protein Kinase C; Tetradecanoylphorbol Acetate

1991
Further evidence for abnormal protein kinase C regulation of macromolecule secretion in fibroblasts from cystic fibrosis patients.
    Bioscience reports, 1990, Volume: 10, Issue:6

    Topics: Binding Sites; Bucladesine; Calcimycin; Cells, Cultured; Colforsin; Cystic Fibrosis; Dose-Response Relationship, Drug; Fibroblasts; Glycoconjugates; Humans; Isoproterenol; Phorbol 12,13-Dibutyrate; Protein Kinase C; Skin; Tetradecanoylphorbol Acetate

1990
Rapid inactivation and phosphorylation of pyroglutamyl peptidase II in Y-79 human retinoblastoma cells after exposure to phorbol ester.
    Endocrinology, 1990, Volume: 127, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Line; Epinephrine; Eye Neoplasms; Humans; Immune Sera; Immunoblotting; Isoquinolines; Kinetics; Molecular Weight; Phorbol 12,13-Dibutyrate; Phosphorylation; Piperazines; Protein Kinase C; Pyroglutamyl-Peptidase I; Retinoblastoma; Sphingosine; Tetradecanoylphorbol Acetate

1990
Tumor-promoting phorbol ester and activated Ha-ras synergistically reduce the interleukin 3 requirement in a mast cell line.
    Cancer research, 1991, Jan-15, Volume: 51, Issue:2

    Topics: Animals; Blotting, Northern; Cell Division; Cell Line; Cell Transformation, Neoplastic; Genes, ras; Genetic Vectors; Interleukin-3; Mast Cells; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Restriction Mapping; Tetradecanoylphorbol Acetate; Transfection

1991
Protein kinase C activation allows pulmonary artery smooth muscle cells to proliferate to hypoxia.
    The American journal of physiology, 1991, Volume: 260, Issue:2 Pt 1

    Topics: Aerobiosis; Anaerobiosis; Animals; Cattle; Cell Division; Cells, Cultured; Dimethyl Sulfoxide; DNA Replication; Enzyme Activation; Hypoxia; Kinetics; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pulmonary Artery; Tetradecanoylphorbol Acetate; Thymidine

1991
Arachidonic acid release by basophilic leukemia cells and macrophages stimulated by Ca2+ ionophores, antigen and diacylglycerol: essential role for protein kinase C and prevention by glucocorticosteroids.
    Biochimica et biophysica acta, 1991, Feb-19, Volume: 1091, Issue:3

    Topics: Alkaloids; Animals; Antigens; Arachidonic Acids; Calcimycin; Carbazoles; Cell Line; Cell Membrane; Cells, Cultured; Dexamethasone; Immunoglobulin E; Indole Alkaloids; Ionomycin; Kinetics; Leukemia, Basophilic, Acute; Leukemia, Experimental; Macrophages; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Protein Kinase C; Rats; Serum Albumin, Bovine; Staurosporine; Tetradecanoylphorbol Acetate

1991
A rapid colorimetric microassay to detect agonists/antagonists of protein kinase C based on adherence of EL-4.IL-2 cells.
    The Journal of antibiotics, 1991, Volume: 44, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Carcinogens; Cell Adhesion; Colorimetry; Diterpenes; Dose-Response Relationship, Drug; Enzyme Activation; Indoles; Isoquinolines; Lactams; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Reproducibility of Results; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured

1991
Transforming growth factor-alpha and -beta are potent and effective inhibitors of GH4 pituitary tumor cell proliferation.
    Endocrinology, 1991, Volume: 128, Issue:4

    Topics: Activins; Animals; Cell Adhesion; Cell Count; Cell Division; DNA; Inhibins; Interphase; Mitosis; Phorbol 12,13-Dibutyrate; Pituitary Neoplasms; Prolactin; Protein Kinase C; Rats; Recombinant Proteins; S Phase; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Transforming Growth Factor beta; Tumor Cells, Cultured

1991
Inhibition of mouse skin protein kinase C by benzoyl peroxide.
    The Journal of investigative dermatology, 1991, Volume: 96, Issue:4

    Topics: Animals; Benzoyl Peroxide; Calcium; Enzyme Activation; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Skin; Tetradecanoylphorbol Acetate

1991
Involvement of protein kinase C in the regulation of ornithine decarboxylase mRNA by phorbol esters in rat hepatoma cells.
    Experimental cell research, 1991, Volume: 194, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Diglycerides; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Isoquinolines; Liver Neoplasms, Experimental; Ornithine Decarboxylase; Palmitoylcarnitine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Type C Phospholipases

1991
In vitro model for intrinsic drug resistance: effects of protein kinase C activators on the chemosensitivity of cultured human colon cancer cells.
    Molecular pharmacology, 1991, Volume: 39, Issue:4

    Topics: Antineoplastic Agents; Colonic Neoplasms; Diglycerides; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Enzyme Activation; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vincristine

1991
Multiple signal transduction pathways lead to extracellular ATP-stimulated mitogenesis in mammalian cells: I. Involvement of protein kinase C-dependent and -independent pathways.
    Journal of cellular physiology, 1991, Volume: 146, Issue:3

    Topics: Adenosine Triphosphate; Animals; Bombesin; Carcinoma, Squamous Cell; Cell Line; Diglycerides; DNA; Down-Regulation; Drug Synergism; Enzyme Activation; Fibroblasts; Glycerides; Humans; Mice; Mitosis; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylcholines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Vasopressins; Virulence Factors, Bordetella

1991
Protein kinase C down-regulation, and not transient activation, correlates with melanocyte growth.
    Cancer research, 1991, Jun-15, Volume: 51, Issue:12

    Topics: Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Division; Cell Line; Enzyme Activation; Kinetics; Melanocytes; Melanoma, Experimental; Mice; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Protein Kinase C; Receptors, Drug; Tetradecanoylphorbol Acetate

1991
NPC 15437 interacts with the C1 domain of protein kinase C. An analysis using mutant PKC constructs.
    FEBS letters, 1991, Jul-08, Volume: 285, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Sequence; Animals; Binding Sites; Cell Line; DNA Mutational Analysis; Isoquinolines; Macromolecular Substances; Molecular Sequence Data; Mutation; Phorbol 12,13-Dibutyrate; Piperazines; Piperidines; Protein Conformation; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Transfection

1991
Interactive effects of aldrin, cyclohexylamine, 2,4-diaminotoluene and two phorbol esters on metabolic cooperation between V79 cells.
    Carcinogenesis, 1991, Volume: 12, Issue:7

    Topics: Aldrin; Cell Communication; Cells, Cultured; Cyclohexylamines; Drug Synergism; Phenylenediamines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate

1991
Outgrowths from Hermissenda photoreceptor somata are associated with activation of protein kinase C.
    Brain research, 1990, Nov-26, Volume: 534, Issue:1-2

    Topics: Animals; Calcium; Cell Membrane; Enzyme Activation; In Vitro Techniques; Learning; Mollusca; Phorbol 12,13-Dibutyrate; Photoreceptor Cells; Potassium Channels; Protein Kinase C; Tetradecanoylphorbol Acetate

1990
Alteration of the GTP-dependent inhibitory pathway of rat striatal adenylate cyclase by phorbol esters.
    Neurochemical research, 1990, Volume: 15, Issue:11

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Corpus Striatum; GTP Phosphohydrolases; Guanosine Triphosphate; Hydrolysis; Male; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1990
Effect of nerve growth factor and fibroblast growth factor on SCG10 and c-fos expression and neurite outgrowth in protein kinase C-depleted PC12 cells.
    The Journal of biological chemistry, 1990, Feb-05, Volume: 265, Issue:4

    Topics: Adrenal Gland Neoplasms; Animals; Axons; Cell Line; Diglycerides; Fibroblast Growth Factors; Gene Expression Regulation; Nerve Growth Factors; Pheochromocytoma; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1990
Selection and preliminary characterization of variant lines of a murine macrophage tumor resistant to the antiproliferative effects of phorbol esters.
    Cancer research, 1990, Mar-01, Volume: 50, Issue:5

    Topics: Animals; Cell Division; Dimethyl Sulfoxide; Drug Resistance; Enzyme Activation; Macrophages; Molecular Weight; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Terbium as a luminescent probe of metal-binding sites in protein kinase C.
    The Journal of biological chemistry, 1990, Mar-15, Volume: 265, Issue:8

    Topics: Binding Sites; Binding, Competitive; Egtazic Acid; Energy Transfer; Humans; Luminescent Measurements; Metals; Phorbol 12,13-Dibutyrate; Phosphatidylserines; Protein Kinase C; Spectrophotometry; Terbium; Tetradecanoylphorbol Acetate

1990
Effects of cigarette smoke condensate and 12-O-tetradecanoylphorbol-13-acetate on gap junction structure and function in cultured cells.
    Carcinogenesis, 1990, Volume: 11, Issue:6

    Topics: Animals; Caenorhabditis elegans Proteins; Calcium Chloride; Carrier Proteins; Cells, Cultured; Chick Embryo; Diglycerides; Egtazic Acid; Freeze Fracturing; Intercellular Junctions; Kinetics; Liver; Microscopy, Electron; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Drug; Smoke; Smoking; Tetradecanoylphorbol Acetate

1990
Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:15

    Topics: Adrenal Gland Neoplasms; Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Animals; Cell Line; Ethers, Cyclic; Humans; Kinetics; Methionine; Molecular Weight; Okadaic Acid; Pheochromocytoma; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Biosynthesis; Protein Kinase C; Protein Precursors; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Transcription, Genetic

1990
Protein kinase C-linked inactivation of the interleukin-1 receptor in a human transformed B-cell line.
    Biochimica et biophysica acta, 1990, Apr-09, Volume: 1052, Issue:1

    Topics: B-Lymphocytes; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Cell Membrane; Enzyme Activation; Humans; Interleukin-1; Kinetics; Lymphoma; Phorbol 12,13-Dibutyrate; Phorbols; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Receptors, Interleukin-1; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Protein kinase C inhibits Ca2+ accumulation in cardiac sarcoplasmic reticulum.
    The Journal of biological chemistry, 1990, Mar-15, Volume: 265, Issue:8

    Topics: Animals; Animals, Newborn; Biological Transport; Calcium; Calcium Radioisotopes; Cells, Cultured; Cyclic AMP; Myocardial Contraction; Myocardium; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred Strains; Ryanodine; Sarcoplasmic Reticulum; Tetradecanoylphorbol Acetate

1990
Regulation of oxytocin secretion by the ovine corpus luteum: effect of activators of protein kinase C.
    The Journal of endocrinology, 1990, Volume: 124, Issue:2

    Topics: Animals; Bucladesine; Calcimycin; Corpus Luteum; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Female; In Vitro Techniques; Oxytocin; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Pyrimidinones; Sheep; Tetradecanoylphorbol Acetate; Thiazoles; Type C Phospholipases

1990
Protein kinase C is involved in desensitization of muscarinic receptors induced by phorbol esters but not by receptor agonists.
    The Biochemical journal, 1990, Apr-01, Volume: 267, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Carbachol; Cyclic GMP; Down-Regulation; Isoquinolines; Mice; N-Methylscopolamine; Neuroblastoma; Parasympathomimetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Receptors, Muscarinic; Scopolamine Derivatives; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Sphingosine differentially inhibits activation of the Na+/H+ exchanger by phorbol esters and growth factors.
    The Journal of biological chemistry, 1990, May-05, Volume: 265, Issue:13

    Topics: Animals; Animals, Newborn; Biological Transport; Carrier Proteins; Cells, Cultured; Detergents; Diglycerides; Hydrogen-Ion Concentration; Kinetics; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Platelet-Derived Growth Factor; Rats; Sodium-Hydrogen Exchangers; Sphingosine; Tetradecanoylphorbol Acetate; Thrombin

1990
Evidence for involvement of protein kinase C and cyclic adenosine 3',5' monophosphate-dependent protein kinase in the 1,25-dihydroxy-vitamin D3-mediated rapid stimulation of intestinal calcium transport, (transcaltachia).
    Endocrinology, 1990, Volume: 127, Issue:1

    Topics: Alkaloids; Animals; Biological Transport; Calcitriol; Calcium; Chickens; Colforsin; Cyclic AMP; Duodenum; Intestinal Mucosa; Intestines; Kinetics; Male; Nifedipine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil; Vitamin D Deficiency

1990
Interferon-alpha selectively activates the beta isoform of protein kinase C through phosphatidylcholine hydrolysis.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:17

    Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cytosol; Diglycerides; Enzyme Activation; HeLa Cells; Humans; Hydrolysis; Interferon Type I; Isoenzymes; Kinetics; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Protein Kinase C; Receptors, Drug; Recombinant Proteins; Tetradecanoylphorbol Acetate; Vesicular stomatitis Indiana virus

1990
Regulation of platelet-activating factor receptor and PAF receptor-mediated arachidonic acid release by protein kinase C activation in rat Kupffer cells.
    Archives of biochemistry and biophysics, 1990, Volume: 282, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Dimethyl Sulfoxide; Down-Regulation; Enzyme Activation; Kinetics; Kupffer Cells; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate

1990
Cross-talk between B cell surface immunoglobulin and interleukin 4 receptors: the role of protein kinase C and Ca2(+)-mediated signals.
    European journal of immunology, 1990, Volume: 20, Issue:10

    Topics: Animals; Antibodies, Monoclonal; B-Lymphocytes; Calcium; DNA; Flow Cytometry; Lymphocyte Activation; Mice; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Receptors, Antigen, B-Cell; Receptors, Interleukin-4; Receptors, Mitogen; Signal Transduction; Tetradecanoylphorbol Acetate

1990
Potentiation of oncogenic N-ras-induced neurite outgrowth and ornithine decarboxylase activity by phorbol dibutyrate and protein kinase inhibitor H-8.
    Journal of cellular physiology, 1990, Volume: 143, Issue:1

    Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Colforsin; Dexamethasone; Epidermal Growth Factor; Isoquinolines; Nerve Growth Factors; Neurons; Oncogene Protein p21(ras); Ornithine Decarboxylase; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase Inhibitors; Rats; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1990
Expression, purification, and characterization of protein kinase C-epsilon.
    The Journal of biological chemistry, 1990, May-05, Volume: 265, Issue:13

    Topics: Alkaloids; Animals; Cell Line; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Diglycerides; DNA; Enzyme Activation; Insect Viruses; Insecta; Isoenzymes; Kinetics; Mice; Phorbol 12,13-Dibutyrate; Plasmids; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate

1990
Protein kinase C-independent activation of nuclear factor kappa B by tumor necrosis factor.
    The Journal of biological chemistry, 1990, May-15, Volume: 265, Issue:14

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Base Sequence; Binding Sites; Cell Line; DNA-Binding Proteins; DNA, Viral; Down-Regulation; Enhancer Elements, Genetic; Enzyme Activation; H-2 Antigens; HIV-1; Humans; Isoquinolines; Leukemia; Molecular Sequence Data; NF-kappa B; Phorbol 12,13-Dibutyrate; Piperazines; Promoter Regions, Genetic; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Necrosis Factor-alpha

1990
Nerve growth factor stimulates protein kinase C translocation in PC12 cells.
    FEBS letters, 1990, May-07, Volume: 264, Issue:1

    Topics: Adrenal Gland Neoplasms; Animals; Cell Line; Fluorescent Antibody Technique; Immunoblotting; Nerve Growth Factors; Pheochromocytoma; Phorbol 12,13-Dibutyrate; Protein Binding; Protein Kinase C; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Reciprocal expression of human ETS1 and ETS2 genes during T-cell activation: regulatory role for the protooncogene ETS1.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:10

    Topics: Calcium; Cells, Cultured; DNA Probes; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation; Genes, Regulator; Humans; Ionomycin; Lymphocyte Activation; Models, Biological; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Protein c-ets-2; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Proto-Oncogenes; Repressor Proteins; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Transcription, Genetic

1990
Long-term treatment of isolated rat soleus muscle with phorbol ester leads to loss of contraction-induced glucose transport.
    The Biochemical journal, 1990, May-01, Volume: 267, Issue:3

    Topics: Animals; Biological Transport; Female; Glucose; Glycogen; In Vitro Techniques; Insulin; Muscle Contraction; Muscles; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1990
The effect of protein kinase-C inhibition on insulin receptor phosphorylation.
    Endocrinology, 1990, Volume: 127, Issue:1

    Topics: Alkaloids; Cell Line; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Insulin; Peptide Mapping; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinase C; Receptor, Insulin; Staurosporine; Tetradecanoylphorbol Acetate; Trypsin

1990
Interaction of insulin and phorbol esters on the regulation of DNA synthesis in rat hepatoma cells.
    Biochemical and biophysical research communications, 1990, Oct-30, Volume: 172, Issue:2

    Topics: Animals; Cell Line; DNA Replication; DNA, Neoplasm; Insulin; Kinetics; Liver Neoplasms, Experimental; Phorbol 12,13-Dibutyrate; Rats; Tetradecanoylphorbol Acetate; Thymidine

1990
Dissociation between protein kinase C content and biological responsiveness to phorbol esters in tumor promoter-sensitive (MCF-7) and resistant (RPh-4) cells.
    Biochemical pharmacology, 1990, Oct-15, Volume: 40, Issue:8

    Topics: Animals; Cell Division; Cell Line; Cell Separation; Drug Resistance; Flow Cytometry; Models, Biological; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Subcellular Fractions; Tetradecanoylphorbol Acetate

1990
Phorbol ester inhibits surfactant protein SP-A and SP-B expression.
    The Journal of biological chemistry, 1990, Dec-05, Volume: 265, Issue:34

    Topics: Adenocarcinoma; Cell Line; Dactinomycin; Enzyme-Linked Immunosorbent Assay; Glycoproteins; Humans; Kinetics; L-Lactate Dehydrogenase; Lung Neoplasms; Methionine; Phorbol 12,13-Dibutyrate; Protein Binding; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1990
Inhibition of noradrenaline release by neuropeptide Y does not involve protein kinase C in mouse atria.
    Neuropeptides, 1990, Volume: 15, Issue:4

    Topics: Animals; Carbazoles; Electric Stimulation; Enzyme Activation; Female; Heart; Heart Atria; In Vitro Techniques; Indole Alkaloids; Mice; Neuropeptide Y; Norepinephrine; Phorbol 12,13-Dibutyrate; Polymyxin B; Protein Kinase C; Tetradecanoylphorbol Acetate; Tritium

1990
Effects of protein kinase C down-regulation on secretory events and proopiomelanocortin gene expression in anterior pituitary tumor (AtT-20) cells.
    Journal of neurochemistry, 1990, Volume: 54, Issue:1

    Topics: Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Cell Membrane; Cytosol; Gene Expression Regulation; Genes; Homeostasis; Kinetics; Phorbol 12,13-Dibutyrate; Phosphorylation; Pituitary Neoplasms; Pro-Opiomelanocortin; Protein Kinase C; Receptors, Drug; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Sphingosine stimulates cellular proliferation via a protein kinase C-independent pathway.
    The Journal of biological chemistry, 1990, Jan-05, Volume: 265, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Division; Cell Line; DNA; Down-Regulation; Drug Synergism; Fibroblasts; Growth Substances; Isoquinolines; Phorbol 12,13-Dibutyrate; Phosphorylation; Piperazines; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate

1990
Transcriptional regulation of protein kinase C by 1,25-dihydroxyvitamin D3 in HL-60 cells.
    The Journal of biological chemistry, 1990, Feb-05, Volume: 265, Issue:4

    Topics: Caenorhabditis elegans Proteins; Calcitriol; Carrier Proteins; Cell Line; Gene Expression Regulation, Enzymologic; Genes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Drug; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1990
Evidence that protein kinase C activation is essential for killing by IL-2-activated lymphocytes.
    Scandinavian journal of immunology, 1990, Volume: 31, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Chromium Radioisotopes; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Interleukin-2; Isoquinolines; Killer Cells, Lymphokine-Activated; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Piperazines; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Rat liver nuclei protein kinase C is the isozyme type II.
    The Journal of biological chemistry, 1990, Mar-05, Volume: 265, Issue:7

    Topics: Animals; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Isoenzymes; Kinetics; Liver; Molecular Weight; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

1990
The effects of teleocidin and aplysiatoxin tumor promoters on epithelial tight junctions and transepithelial permeability: comparison to phorbol esters.
    Carcinogenesis, 1990, Volume: 11, Issue:3

    Topics: Carcinogens; Cells, Cultured; Dose-Response Relationship, Drug; Epithelium; Intercellular Junctions; Lyngbya Toxins; Permeability; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate

1990
Protein kinase C levels and protein phosphorylation associated with inhibition of proliferation in a murine macrophage tumor.
    Journal of cellular physiology, 1990, Volume: 142, Issue:3

    Topics: Animals; Cell Division; Diglycerides; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Isoelectric Point; Macrophages; Mice; Molecular Weight; Phorbol 12,13-Dibutyrate; Phosphoproteins; Protein Kinase C; Sarcoma, Experimental; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1990
Histamine receptors in human fibroblasts: inositol phosphates, Ca2+, and cell growth.
    The American journal of physiology, 1990, Volume: 258, Issue:3 Pt 1

    Topics: Aminopyridines; Calcium; Cell Division; Cell Line; DNA Replication; Fibroblasts; Fluorescent Dyes; Histamine; Humans; Inositol Phosphates; Kinetics; Phorbol 12,13-Dibutyrate; Pyrilamine; Receptors, Histamine; Skin; Tetradecanoylphorbol Acetate; Thymidine

1990
The effects of phorbol esters on choline phospholipid hydrolysis in heart and brain.
    European journal of pharmacology, 1990, Mar-13, Volume: 188, Issue:2-3

    Topics: Animals; Brain Chemistry; Chickens; Heart; Hydrolysis; In Vitro Techniques; Male; Myocardium; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylcholines; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1990
A point mutation at the putative ATP-binding site of protein kinase C alpha abolishes the kinase activity and renders it down-regulation-insensitive. A molecular link between autophosphorylation and down-regulation.
    The Journal of biological chemistry, 1990, Apr-15, Volume: 265, Issue:11

    Topics: Adenosine Triphosphate; Animals; Base Sequence; Cell Line; Cytosol; DNA; Genetic Vectors; Homeostasis; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Phorbol 12,13-Dibutyrate; Phosphorylation; Plasmids; Protein Kinase C; Rats; Subcellular Fractions; Tetradecanoylphorbol Acetate

1990
Regulation of megakaryocyte phenotype in human erythroleukemia cells.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:4

    Topics: Antigens; Cell Differentiation; Cell Division; Cell Fusion; Humans; Interphase; Leukemia, Erythroblastic, Acute; Megakaryocytes; Phenotype; Phorbol 12,13-Dibutyrate; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Activation of human T lymphocytes by phorbol-12,13-dibutyrate and ionomycin.
    Scandinavian journal of immunology, 1990, Volume: 31, Issue:3

    Topics: Antibodies, Monoclonal; Calcium; Drug Synergism; Humans; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Phytohemagglutinins; Protein Kinase C; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors

1990
Positive and negative regulation of a tumor necrosis factor response in melanoma cells.
    The Journal of biological chemistry, 1990, Apr-25, Volume: 265, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; DNA Probes; Female; Humans; Isoquinolines; Kinetics; Melanoma; Phorbol 12,13-Dibutyrate; Piperazines; Plasminogen Activators; Plasminogen Inactivators; Pregnancy; Protein Kinase Inhibitors; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1990
Regulation of angiotensin II binding sites in neuronal cultures by protein kinase C.
    The American journal of physiology, 1990, Volume: 258, Issue:4 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Animals, Newborn; Brain Stem; Cells, Cultured; Homeostasis; Hypothalamus; Isoquinolines; Kinetics; Neurons; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetradecanoylphorbol Acetate

1990
Effects of bryostatins 1 and 2 on morphological and functional differentiation of SH-SY5Y human neuroblastoma cells.
    Cancer research, 1990, Jun-01, Volume: 50, Issue:11

    Topics: Antineoplastic Agents; Bryostatins; DNA, Neoplasm; Down-Regulation; Enzyme Induction; Humans; Lactones; Macrolides; Neuroblastoma; Norepinephrine; Oncogenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Differential activation of protein kinase C alpha is associated with arachidonate release in Madin-Darby canine kidney cells.
    The Journal of biological chemistry, 1990, May-25, Volume: 265, Issue:15

    Topics: Animals; Arachidonic Acids; Bradykinin; Cell Line; Diglycerides; Dogs; Enzyme Activation; Kidney; Kinetics; Phorbol 12,13-Dibutyrate; Phospholipids; Protein Kinase C; Tetradecanoylphorbol Acetate

1990
Involvement of protein kinase C in phorbol ester-induced sensitization of HeLa cells to cis-diamminedichloroplatinum(II).
    The Journal of biological chemistry, 1990, May-25, Volume: 265, Issue:15

    Topics: Cell Division; Cell Line; Cell Survival; Cisplatin; HeLa Cells; Humans; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Effect of phorbol esters on the susceptibility of a glioma cell line to lymphokine-activated killer cell activity.
    Journal of neurosurgery, 1990, Volume: 73, Issue:1

    Topics: Cell Division; Glioma; Humans; Killer Cells, Lymphokine-Activated; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured

1990
Human growth hormone-stimulated growth of human cultured lymphocytes (IM-9) and its inhibition by phorbol diesters through down-regulation of the hormone receptors. Possible involvement of phosphorylation of a 55,000 molecular weight protein associated wi
    The Journal of biological chemistry, 1990, Jul-05, Volume: 265, Issue:19

    Topics: Alkaloids; Blood; Cell Division; Cell Line; Down-Regulation; Enzyme Activation; Growth Hormone; Humans; Kinetics; Lymphocytes; Molecular Weight; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphoproteins; Phosphorylation; Protein Kinase C; Receptors, Somatotropin; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate

1990
Phorbol esters induce neurotransmitter release in cholinergic synaptosomes from Torpedo electric organ.
    Journal of neurochemistry, 1990, Volume: 55, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Botulinum Toxins; Dose-Response Relationship, Drug; Electric Organ; Isoquinolines; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Potassium Chloride; Protein Kinase C; Synaptosomes; Tetradecanoylphorbol Acetate; Torpedo

1990
Partial characterization of epidermal protein kinase C in mice sensitive or resistant to phorbol ester.
    Molecular carcinogenesis, 1990, Volume: 3, Issue:3

    Topics: Animals; Binding Sites; Biological Transport; Down-Regulation; Drug Resistance; Female; Isoenzymes; Mice; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Protein Kinase C; Skin; Species Specificity; Tetradecanoylphorbol Acetate

1990
Abnormal behavior of protein kinase C in the human myeloma cell line, RPMI 8226.
    FEBS letters, 1990, Sep-03, Volume: 269, Issue:2

    Topics: Animals; Brain; Cell Fractionation; Cell Line; Cell Membrane; Chromatography, DEAE-Cellulose; Cytosol; Humans; Kinetics; Multiple Myeloma; Phorbol 12,13-Dibutyrate; Protein Binding; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Time Factors

1990
Contrasting effects of phorbol dibutyrate and phorbol myristate acetate in rabbit aorta.
    Biochemical and biophysical research communications, 1990, Sep-14, Volume: 171, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta; Cells, Cultured; Epinephrine; In Vitro Techniques; Isoquinolines; Liver; Muscle Contraction; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Phosphates; Phosphatidylinositols; Piperazines; Protein Kinase Inhibitors; Rabbits; Tetradecanoylphorbol Acetate

1990
Beta-adrenergic stimulation of anterior pituitary cyclic AMP is enhanced by tumor promoters.
    Endocrine research, 1985, Volume: 11, Issue:3-4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pituitary Gland, Anterior; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate

1985
Enhancement of phorbol diester-induced HL-60-mediated cytotoxicity by retinoic acid, dimethyl sulfoxide, and 5-azacytidine.
    Cancer research, 1986, Volume: 46, Issue:8

    Topics: Azacitidine; Cell Differentiation; Cell Line; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate; Tretinoin

1986
Down regulation of phorbol diester receptors by proteolytic degradation of protein kinase C in a cultured cell line of fetal rat skin keratinocytes.
    The Journal of biological chemistry, 1986, Oct-05, Volume: 261, Issue:28

    Topics: Animals; Caenorhabditis elegans Proteins; Calcium; Carrier Proteins; Cell Line; Chromatography, Gel; Cytosol; Diglycerides; Female; Keratins; Leupeptins; Molecular Weight; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylserines; Pregnancy; Protein Kinase C; Rats; Receptors, Drug; Receptors, Immunologic; Skin; Tetradecanoylphorbol Acetate; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone

1986
Effects of phorbol esters and pertussis toxin on agonist-stimulated cyclic AMP production in rat osteosarcoma cells.
    Biochemical pharmacology, 1986, Oct-15, Volume: 35, Issue:20

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Cyclic AMP; Drug Synergism; Interphase; Osteosarcoma; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella

1986
Dual actions of phorbol esters to decrease calcium and potassium conductances of mouse neurons.
    Neuroscience letters, 1987, Jul-09, Volume: 78, Issue:1

    Topics: Animals; Calcium; Cells, Cultured; Enzyme Activation; Ganglia, Spinal; Ion Channels; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Potassium; Protein Kinase C; Spinal Cord; Telencephalon; Tetradecanoylphorbol Acetate

1987
Phorbol ester binding and protein kinase C activity in normal and transformed human keratinocytes.
    Experimental cell research, 1987, Volume: 172, Issue:1

    Topics: Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Line; Cell Transformation, Viral; Cells, Cultured; Epidermal Cells; Epidermis; ErbB Receptors; Humans; Keratins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Drug; Simian virus 40; Tetradecanoylphorbol Acetate

1987
A phorbol ester-sensitive kinase catalyzes the phosphorylation of P0 glycoprotein in myelin.
    Journal of neurochemistry, 1987, Volume: 49, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Cycloheximide; Enzyme Activation; Male; Molecular Weight; Myelin P0 Protein; Myelin Proteins; Myelin Sheath; Nerve Crush; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphates; Phosphorylation; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1987
Protein kinase C potentiates isoproterenol-mediated cyclic AMP production without modifying the homologous desensitization process in J774 cells.
    European journal of biochemistry, 1987, Dec-30, Volume: 170, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Carcinogens; Cell Line; Cell Membrane; Cyclic AMP; Isoproterenol; Kinetics; Macrophages; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate

1987
Immature stimulus-secretion coupling in the developing exocrine pancreas and ontogenic changes of protein kinase C.
    Biochimica et biophysica acta, 1988, Feb-22, Volume: 968, Issue:2

    Topics: Amylases; Animals; Animals, Newborn; Bucladesine; Calcimycin; Cytosol; Fetus; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Rats, Inbred Strains; Secretory Rate; Sincalide; Tetradecanoylphorbol Acetate

1988
Phorbol esters modulate cyclic AMP accumulation in porcine thyroid cells.
    Life sciences, 1988, Volume: 42, Issue:22

    Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin

1988
Interactions between phorbol esters and agents which increase cytosolic calcium in the guinea pig parenchymal strip: direct and indirect effects on the contractile response.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium; Cytosol; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Lung; Male; Muscle Contraction; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate; Vanadates

1988
Two modes of regulation of the phospholipase C-linked substance-P receptor in rat parotid acinar cells.
    The Biochemical journal, 1988, Jul-15, Volume: 253, Issue:2

    Topics: Animals; Binding Sites; Calcium; Enzyme Activation; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Parotid Gland; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Tetradecanoylphorbol Acetate; Type C Phospholipases

1988
Adenosine 3',5'-cyclic monophosphate (cAMP) inhibits phorbol ester-induced growth of an IL-2-dependent T cell line.
    FEBS letters, 1988, Nov-07, Volume: 239, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Cell Division; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; DNA Replication; Humans; Interleukin-2; Kinetics; Phorbol 12,13-Dibutyrate; Recombinant Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate

1988
Phorbol ester-mediated down-regulation of an interferon-inducible gene.
    The Journal of biological chemistry, 1989, Feb-25, Volume: 264, Issue:6

    Topics: Cycloheximide; Fibroblasts; Gene Expression Regulation; Humans; Interferon Type I; Melanoma; Phorbol 12,13-Dibutyrate; Recombinant Proteins; RNA; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1989
Opposing effects of calcium entry and phorbol esters on fusion of chick muscle cells.
    Developmental biology, 1989, Volume: 134, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium Channel Blockers; Cell Fusion; Cells, Cultured; Chick Embryo; Egtazic Acid; Gallopamil; Kinetics; Muscles; Myosin Subfragments; Myosin-Light-Chain Kinase; Myosins; Nitrendipine; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Tetradecanoylphorbol Acetate

1989
Activators of protein kinase C up-regulate the cell surface expression of CD2 and CD5 T cell glycoproteins.
    The Journal of biological chemistry, 1989, Sep-15, Volume: 264, Issue:26

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies, Monoclonal; Antigens, Differentiation; Antigens, Differentiation, T-Lymphocyte; Calcium Channel Blockers; CD2 Antigens; CD5 Antigens; Cell Membrane; Cells, Cultured; Cycloheximide; Diglycerides; Dinoprostone; Enzyme Activation; Flow Cytometry; Humans; Isoquinolines; Membrane Glycoproteins; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Receptors, Immunologic; RNA, Messenger; Sulfonamides; T-Lymphocytes; Tetradecanoylphorbol Acetate

1989
Regulation of phospholipase D in HL-60 granulocytes. Activation by phorbol esters, diglyceride, and calcium ionophore via protein kinase- independent mechanisms.
    The Journal of biological chemistry, 1989, May-25, Volume: 264, Issue:15

    Topics: Calcimycin; Cell Line; Diglycerides; Enzyme Activation; Glycerides; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phorbol 12,13-Dibutyrate; Phospholipase D; Phospholipases; Protein Kinase C; Tetradecanoylphorbol Acetate

1989
Evidence that phorbol diester-sensitive protein kinase-C(s) may not be directly involved in secretagogue-stimulated prolactin release and arachidonate liberation.
    Endocrinology, 1989, Volume: 125, Issue:3

    Topics: Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Cells, Cultured; Female; Kinetics; Marine Toxins; Neurotensin; Oxocins; Phorbol 12,13-Dibutyrate; Pituitary Gland, Anterior; Prolactin; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone

1989
Inhibition of DNA fragmentation in thymocytes and isolated thymocyte nuclei by agents that stimulate protein kinase C.
    The Journal of biological chemistry, 1989, Aug-15, Volume: 264, Issue:23

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcium; Cell Nucleus; Cells, Cultured; Cytosol; DNA; Isoquinolines; Kinetics; Male; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thymus Gland

1989
Ca2+- and phospholipid-independent activation of protein kinase C by selective oxidative modification of the regulatory domain.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:17

    Topics: Animals; Brain; Calcium; Cattle; Cell Line; Egtazic Acid; Enzyme Activation; Glioma; Hydrogen Peroxide; Kinetics; Phorbol 12,13-Dibutyrate; Phosphatidylserines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate

1989
Involvement of protein kinase C in translocation of desmoplakins from cytosol to plasma membrane during desmosome formation in human squamous cell carcinoma cells grown in low to normal calcium concentration.
    Experimental cell research, 1989, Volume: 185, Issue:1

    Topics: Calcimycin; Calcium; Carcinoma, Squamous Cell; Cell Membrane; Cytoskeletal Proteins; Cytosol; Desmoplakins; Desmosomes; Diglycerides; Dose-Response Relationship, Drug; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Homologous desensitization of muscarinic cholinergic, histaminergic, adrenergic, and serotonergic receptors coupled to phospholipase C in cerebellar granule cells.
    Journal of neurochemistry, 1989, Volume: 52, Issue:2

    Topics: Animals; Carbachol; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Histamine; Inositol Phosphates; Norepinephrine; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Histamine; Receptors, Muscarinic; Receptors, Serotonin; Serotonin; Tetradecanoylphorbol Acetate; Type C Phospholipases

1989
Evidence for a protein kinase C-directed mechanism in the phorbol diester-induced phospholipase D pathway of diacylglycerol generation from phosphatidylcholine.
    FEBS letters, 1989, Mar-13, Volume: 245, Issue:1-2

    Topics: Alkaloids; Animals; Bucladesine; Cell Line; Choline; Colforsin; Diglycerides; Embryo, Mammalian; Fibroblasts; Glycerides; Glycerophospholipids; Hydrolysis; Myristic Acid; Myristic Acids; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phospholipases; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate

1989
Requirement and role of arachidonic acid in the differentiation of pre-adipose cells.
    The Biochemical journal, 1989, Jan-15, Volume: 257, Issue:2

    Topics: Adipose Tissue; Animals; Arachidonic Acid; Arachidonic Acids; Cell Differentiation; Cell Line; Cyclic AMP; Cyclic GMP; Ethers; Inositol; Ionomycin; Mice; Mice, Inbred C57BL; Mitosis; Phorbol 12,13-Dibutyrate; Phospholipids; Rats; Tetradecanoylphorbol Acetate

1989
Sphingosine inhibits phorbol 12-myristate 13-acetate-, but not serum-induced, activation of Na+/H+ exchange in mammalian cells.
    Journal of cellular physiology, 1989, Volume: 139, Issue:1

    Topics: Animals; Blood Physiological Phenomena; Carrier Proteins; Cell Line; Diglycerides; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Phorbol 12,13-Dibutyrate; Protein Kinase C; Sodium-Hydrogen Exchangers; Sphingosine; Tetradecanoylphorbol Acetate

1989
Enhanced responsiveness to angiotensin II in vascular smooth muscle cells from spontaneously hypertensive rats is not associated with alterations in protein kinase C.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 14, Issue:3

    Topics: Angiotensin II; Animals; Cells, Cultured; Enzyme Activation; Hydrogen-Ion Concentration; Hypertension; Intracellular Membranes; Male; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetradecanoylphorbol Acetate

1989
1,2-dioctanoyl-sn-glycerol can stimulate neutrophils by different mechanisms. Evidence for a pathway that does not involve phosphorylation of the 47-kDa protein.
    The Journal of biological chemistry, 1989, Dec-05, Volume: 264, Issue:34

    Topics: Alkaloids; Animals; Diglycerides; Diterpenes; Glycerides; Guinea Pigs; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Proteins; Staurosporine; Superoxides; Terpenes; Tetradecanoylphorbol Acetate

1989
Mechanistic studies on the DDT-induced inhibition of intercellular communication.
    Carcinogenesis, 1989, Volume: 10, Issue:3

    Topics: Animals; Cell Communication; Cells, Cultured; Cricetinae; DDT; gamma-Glutamyltransferase; Liver; Phorbol 12,13-Dibutyrate; Protein Kinase C; Quercetin; Tetradecanoylphorbol Acetate

1989
Selective low level of protein kinase C isozyme in a tumor promoter-dependent mouse leukemia cell line.
    Biochemical and biophysical research communications, 1989, Nov-15, Volume: 164, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Caenorhabditis elegans Proteins; Carrier Proteins; Isoenzymes; Leukemia, Experimental; Mice; Mutation; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinases; Receptors, Drug; Tetradecanoylphorbol Acetate

1989
Differences in the effects of phorbol esters and diacylglycerols on protein kinase C.
    Biochemistry, 1989, Nov-28, Volume: 28, Issue:24

    Topics: Animals; Calcium; Cattle; Diglycerides; Enzyme Activation; Glycerides; Kinetics; Membrane Proteins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate

1989
Do phorbol myristate and phorbol dibutyrate enhance noradrenaline release by the same mechanisms?
    British journal of pharmacology, 1989, Volume: 98 Suppl

    Topics: Animals; Electric Stimulation; Heart; In Vitro Techniques; Mice; Muscle, Smooth, Vascular; Norepinephrine; Phorbol 12,13-Dibutyrate; Tetradecanoylphorbol Acetate

1989
Activation of HIV gene expression during monocyte differentiation by induction of NF-kappa B.
    Nature, 1989, May-04, Volume: 339, Issue:6219

    Topics: Cell Differentiation; Chloramphenicol O-Acetyltransferase; DNA, Viral; Enhancer Elements, Genetic; Gene Expression Regulation; HIV; Leukemia; Monocytes; NF-kappa B; Phorbol 12,13-Dibutyrate; Plasmids; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1989
Endothelin stimulates diacylglycerol accumulation and activates protein kinase C in cultured vascular smooth muscle cells.
    The Journal of biological chemistry, 1989, May-15, Volume: 264, Issue:14

    Topics: Animals; Aorta, Thoracic; Cells, Cultured; Diglycerides; Endothelins; Endothelium, Vascular; Enzyme Activation; Ethers; Glycerides; Ionomycin; Kinetics; Molecular Weight; Muscle, Smooth, Vascular; Peptides; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

1989
Use of protein kinase C-depleted cells for investigation of the role of protein kinase C in stimulus-response coupling in the pituitary.
    Methods in enzymology, 1989, Volume: 168

    Topics: Animals; Cells, Cultured; Culture Techniques; Female; Kinetics; Luteinizing Hormone; Phorbol 12,13-Dibutyrate; Phosphorus Radioisotopes; Pituitary Gland; Protein Kinase C; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Tritium

1989
Regulation of human megakaryocytopoiesis.
    Annals of the New York Academy of Sciences, 1989, Volume: 554

    Topics: Bone Marrow Cells; Cell Division; Cell Line; Colony-Stimulating Factors; Culture Media; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Hematopoietic Stem Cells; Humans; Interleukin-3; Megakaryocytes; Phorbol 12,13-Dibutyrate; Radioimmunoassay; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Inhibition of protein kinase C-dependent cellular proliferation by interaction of endogenous ganglioside GM1 with the B subunit of cholera toxin.
    The Journal of biological chemistry, 1989, Oct-05, Volume: 264, Issue:28

    Topics: Animals; Caenorhabditis elegans Proteins; Calcium; Carrier Proteins; Cell Division; Cells, Cultured; Cholera Toxin; Cytoplasm; DNA; DNA Replication; G(M1) Ganglioside; Insulin; Mice; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Protein Binding; Protein Kinase C; Receptors, Drug; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1989
Protein synthesis in rat cardiac myocytes is stimulated at the level of translation by phorbol esters.
    FEBS letters, 1989, Apr-24, Volume: 247, Issue:2

    Topics: Animals; Dactinomycin; Kinetics; Male; Myocardium; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Biosynthesis; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Transcription, Genetic

1989
Protein kinase C activity can desensitize the gonadotropin-responsive adenylate cyclase in Leydig tumor cells. But hCG-induced desensitization does not involve protein kinase C activation.
    The Journal of biological chemistry, 1989, May-25, Volume: 264, Issue:15

    Topics: Adenylyl Cyclases; Animals; Binding Sites; Cell Line; Chorionic Gonadotropin; Diglycerides; Enzyme Activation; Inositol; Kinetics; Leydig Cell Tumor; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate

1989
Morphological changes and neural cell adhesion molecule expression in mouse cerebrum primary cultures following long-term exposure to phorbol ester.
    Neuroscience research, 1989, Volume: 6, Issue:4

    Topics: Animals; Antigens, Surface; Astrocytes; Cell Adhesion Molecules; Cell Differentiation; Cells, Cultured; Cerebral Cortex; Glial Fibrillary Acidic Protein; Hippocampus; Mice; Mice, Inbred ICR; Phorbol 12,13-Dibutyrate; Tetradecanoylphorbol Acetate; Time Factors

1989
Differential effects of phorbol esters on PGE2 and bradykinin-induced elevation of [Cai2+] in MDCK cells.
    The American journal of physiology, 1989, Volume: 256, Issue:6 Pt 2

    Topics: Animals; Benzofurans; Bradykinin; Calcium; Cell Line; Dinoprostone; Fluorescent Dyes; Fura-2; Kidney; Kinetics; Phorbol 12,13-Dibutyrate; Prostaglandins; Tetradecanoylphorbol Acetate

1989
Protein kinase C activity and phorbol ester binding to rat myogenic cells during growth and differentiation.
    Experimental cell research, 1989, Volume: 183, Issue:1

    Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Cells, Cultured; Muscles; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1989
Direct activation of a protein kinase activity from rat lacrimal gland by PMA in a phospholipid-free system.
    FEBS letters, 1989, Jul-31, Volume: 252, Issue:1-2

    Topics: Animals; Chromatography, DEAE-Cellulose; Enzyme Activation; Lacrimal Apparatus; Male; Phorbol 12,13-Dibutyrate; Phospholipids; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Type C Phospholipases

1989
(-)-Indolactam V activates protein kinase C and induces changes in muscarinic receptor functions in SH-SY5Y human neuroblastoma cells.
    Biochemical and biophysical research communications, 1989, Aug-15, Volume: 162, Issue:3

    Topics: Calcium; Cell Compartmentation; Cell Differentiation; Cell Membrane; Enzyme Activation; Humans; Indoles; Lactams; Neuroblastoma; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Alteration in protein kinase C activity and subcellular distribution in sickle erythrocytes.
    Biochimica et biophysica acta, 1989, Aug-21, Volume: 984, Issue:1

    Topics: Anemia, Sickle Cell; Cytosol; Erythrocytes; Humans; Membrane Proteins; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Reticulocytes; Tetradecanoylphorbol Acetate

1989
Modification of protein kinase C (PKC) activity and diacylglycerol (DAG) accumulation in hepatocytes in continuous endotoxemia.
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Animals; Biological Transport; Cytosol; Diglycerides; Endotoxins; Glycerides; Kinetics; Liver; Male; Phenylephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins

1989
Transcriptional regulation of transferrin receptor expression by cultured lymphoblastoid T cells treated with phorbol diesters.
    Journal of immunology (Baltimore, Md. : 1950), 1989, Mar-01, Volume: 142, Issue:5

    Topics: Antigens, Surface; Cell Line; Humans; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Protein Processing, Post-Translational; Receptors, Transferrin; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic

1989
Effects of cadmium on lymphocyte activation.
    Biochimica et biophysica acta, 1989, Mar-28, Volume: 1011, Issue:1

    Topics: Adult; Cadmium; Cadmium Chloride; Cadmium Radioisotopes; Calcium; Cell Division; Cell Membrane; Dose-Response Relationship, Drug; Humans; Interleukins; Kinetics; Lymphocyte Activation; Lymphocytes; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Phospholipids; Phytohemagglutinins; Protein Kinases; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate

1989
Phorbol ester and calcium ionophore are sufficient to promote cell replication in cultures of quiescent human B lymphocytes.
    Immunology, 1989, Volume: 66, Issue:2

    Topics: B-Lymphocytes; Cell Division; Cells, Cultured; Ethers; Humans; Ionomycin; Ionophores; Leukocyte Count; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Tetradecanoylphorbol Acetate

1989
Inhibition of the CD3-mediated calcium signal by protein kinase C activators in human T (Jurkat) lymphoblastoid cells.
    Immunology letters, 1989, Jan-15, Volume: 20, Issue:1

    Topics: Antigens, Differentiation, T-Lymphocyte; Calcium; Cell Line; Depression, Chemical; Diglycerides; Enzyme Activation; Glycerides; Humans; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Influence of protein kinase C activators on vascular tone and adrenergic neuroeffector events in the isolated rat kidney.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:2

    Topics: Animals; Calcium; Enzyme Activation; In Vitro Techniques; Kidney; Male; Nifedipine; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasoconstriction

1989
Changes in protein kinase C and cAMP-dependent kinase in lymphocytes after treatment with 12-O-tetradecanoylphorbol-13-acetate or concanavalin A: quantitation of activities with an in situ gel assay.
    Journal of cellular physiology, 1987, Volume: 132, Issue:3

    Topics: Affinity Labels; Animals; Azides; Cattle; Chromatography, Affinity; Concanavalin A; Cyclic AMP; Isoenzymes; Lymphocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Time Factors

1987
Differential sensitivity of agonist- and antagonist-occupied gonadotropin-releasing hormone receptors to protein kinase C activators. A marker for receptor activation.
    The Journal of biological chemistry, 1988, Mar-05, Volume: 263, Issue:7

    Topics: Animals; Buserelin; Cell Membrane; Cells, Cultured; Diglycerides; Enzyme Activation; Female; Glycerides; Gonadotropin-Releasing Hormone; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pituitary Gland; Protein Kinase C; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, LHRH; Tetradecanoylphorbol Acetate

1988
Interferon and phorbol esters down-regulate sIgM expression by independent pathways.
    Journal of cellular physiology, 1988, Volume: 134, Issue:2

    Topics: 2',5'-Oligoadenylate Synthetase; Carrier Proteins; Cell Cycle; Cell Division; Cell Line; Cycloheximide; Enzyme Activation; Immunoglobulin M; Interferon Type I; Lymphocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Biosynthesis; Receptors, Antigen, B-Cell; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Thymidine

1988
Phorbol esters increase adenylate cyclase activity and stability in pituitary membranes.
    Biochemical and biophysical research communications, 1988, Feb-29, Volume: 151, Issue:1

    Topics: Adenylyl Cyclases; Calcium; Cell Membrane; Cyclic AMP; Humans; Kinetics; Models, Biological; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pituitary Neoplasms; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988
Gonadotropin-releasing hormone agonist activates protein kinase C in rat Leydig cells.
    Molecular and cellular endocrinology, 1988, Volume: 55, Issue:1

    Topics: Animals; Buserelin; Cell Membrane; Cyclic AMP; Enzyme Activation; In Vitro Techniques; Leydig Cells; Male; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Rats, Inbred Strains; Testosterone; Tetradecanoylphorbol Acetate

1988
Involvement of two intracellular messenger systems, protein kinase C and cyclic AMP, in the regulation of c-fos gene expression in human promyelocytic leukemia (HL-60) cells.
    Journal of biochemistry, 1987, Volume: 102, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cyclic AMP; Diglycerides; Dinoprostone; Gene Expression Regulation; Humans; Kinetics; Leukemia, Myeloid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Protein Kinase C; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1987
Heterologous down-regulation of vascular atrial natriuretic peptide receptors by phorbol esters.
    Biochemical and biophysical research communications, 1988, May-16, Volume: 152, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Temperature; Tetradecanoylphorbol Acetate; Time Factors

1988
Phorbol ester modulates serotonin-stimulated phosphoinositide breakdown in cultured vascular smooth muscle cells.
    Biochemical and biophysical research communications, 1988, May-31, Volume: 153, Issue:1

    Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; GTP-Binding Proteins; Kinetics; Male; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Phosphorylation; Rabbits; Receptors, Serotonin; Serotonin; Tetradecanoylphorbol Acetate; Type C Phospholipases

1988
Modulation of octopamine-mediated production of cyclic AMP by phorbol-ester-sensitive protein kinase C in an insect cell line.
    Biochimica et biophysica acta, 1988, Jul-29, Volume: 970, Issue:3

    Topics: Animals; Cell Line; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Lepidoptera; Octopamine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate

1988
Participation of protein kinase C and regulatory G proteins in modulation of the evoked noradrenaline release in brain.
    Cellular and molecular neurobiology, 1988, Volume: 8, Issue:1

    Topics: Adenylyl Cyclases; Animals; Electric Stimulation; GTP-Binding Proteins; Hippocampus; In Vitro Techniques; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rabbits; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate

1988
Platelet-derived growth factor (PDGF)-induced phospholipase C-mediated hydrolysis of phosphoinositides in vascular smooth muscle cells--different sensitivity of PDGF- and angiotensin II-induced phospholipase C reactions to protein kinase C-activating phor
    Biochemical and biophysical research communications, 1988, Oct-31, Volume: 156, Issue:2

    Topics: Angiotensin II; Animals; Cells, Cultured; DNA; Enzyme Activation; Hydrolysis; Inositol; Inositol Phosphates; Kinetics; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Platelet-Derived Growth Factor; Protein Kinase C; Rabbits; Recombinant Proteins; Tetradecanoylphorbol Acetate; Type C Phospholipases

1988
Agonist but not phorbol ester induced desensitization of human lymphocyte prostaglandin receptor is dependent on tubulin polymerization.
    Biochemical and biophysical research communications, 1988, Dec-30, Volume: 157, Issue:3

    Topics: Benzimidazoles; Binding, Competitive; Carcinogens; Colchicine; Cyclic AMP; Dinoprostone; Humans; Leukemia, T-Cell; Nocodazole; Phorbol 12,13-Dibutyrate; Phorbol Esters; Receptors, Prostaglandin; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured

1988
Protein kinase C activities are increased in rat thyroid epithelial cells expressing v-ras genes.
    Biochemical and biophysical research communications, 1988, Dec-30, Volume: 157, Issue:3

    Topics: Animals; Biological Transport; Calcium; Cell Membrane; Cell Transformation, Viral; Chromatography; Cytoplasm; Diglycerides; Enzyme Activation; Epithelium; Genes, ras; Harvey murine sarcoma virus; Mutation; Phorbol 12,13-Dibutyrate; Phosphatidylserines; Phosphorylation; Protein Kinase C; Rats; Sarcoma Viruses, Murine; Tetradecanoylphorbol Acetate; Thyroid Gland

1988
Effect of membrane perturbation on protein kinase C activation: treatment with exogenous phospholipase C decreases translocation of enzyme to cellular membranes.
    Biochemical and biophysical research communications, 1986, May-14, Volume: 136, Issue:3

    Topics: Animals; Cell Line; Cell Membrane; Clostridium perfringens; Diglycerides; Enzyme Activation; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Type C Phospholipases

1986
Protein kinase C enhances growth hormone releasing factor (1-40)-stimulated cyclic AMP levels in anterior pituitary. Actions of somatostatin and pertussis toxin.
    The Journal of biological chemistry, 1986, Oct-25, Volume: 261, Issue:30

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cells, Cultured; Cyclic AMP; Drug Synergism; Female; Growth Hormone-Releasing Hormone; Male; Peptide Fragments; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pituitary Gland, Anterior; Protein Kinase C; Rats; Somatostatin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1986
Neurotransmitter-stimulated inositol phosphate accumulation in hippocampal slices.
    Methods in enzymology, 1987, Volume: 141

    Topics: Animals; Carbachol; Hippocampus; In Vitro Techniques; Inositol; Inositol Phosphates; Kinetics; Manganese; Neurotransmitter Agents; Phorbol 12,13-Dibutyrate; Phorbol Esters; Radioisotope Dilution Technique; Sugar Phosphates; Tetradecanoylphorbol Acetate; Tritium

1987
Partial parallelism and partial blockade by bryostatin 1 of effects of phorbol ester tumor promoters on primary mouse epidermal cells.
    Cancer research, 1987, Oct-15, Volume: 47, Issue:20

    Topics: Animals; Bryostatins; Cells, Cultured; Cycloheximide; Dactinomycin; Enzyme Activation; Epidermal Growth Factor; Epidermis; Lactones; Macrolides; Mice; Ornithine Decarboxylase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transglutaminases

1987
Phorbol esters attenuate glutamate-stimulated inositol phospholipid hydrolysis in neuronal cultures.
    Journal of neurochemistry, 1988, Volume: 51, Issue:4

    Topics: Animals; Aspartic Acid; Carbachol; Cerebellum; Diglycerides; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; N-Methylaspartate; Neurons; Oxadiazoles; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Sphingosine; Tetradecanoylphorbol Acetate

1988
Phorbol ester-induced activation of protein kinase C leads to increased formation of diacylglycerol in human neutrophils.
    Experimental cell research, 1989, Volume: 181, Issue:1

    Topics: Calcium; Diglycerides; Enzyme Activation; Glycerides; Humans; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate

1989
Tumor-promoting phorbol esters inhibit monocyte adherence to endothelial cells.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:1

    Topics: Animals; Aorta; Carcinogens; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Male; Monocytes; Phorbol 12,13-Dibutyrate; Phorbols; Tetradecanoylphorbol Acetate

1989
Membrane-phorbol ester interactions monitored by circular dichroism.
    Biochimica et biophysica acta, 1989, Mar-13, Volume: 979, Issue:3

    Topics: Circular Dichroism; Enzyme Activation; Erythrocyte Membrane; Humans; Liposomes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylserines; Protein Kinase C; Spectrum Analysis; Tetradecanoylphorbol Acetate

1989
Differences in phorbol-ester-induced down-regulation of protein kinase C between cell lines.
    The Biochemical journal, 1989, Feb-01, Volume: 257, Issue:3

    Topics: Animals; Binding Sites; Cell Line; Cricetinae; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
Cremophor EL, a widely used parenteral vehicle, is a potent inhibitor of protein kinase C.
    Biochemical and biophysical research communications, 1989, Mar-31, Volume: 159, Issue:3

    Topics: Binding, Competitive; Cell Line; DNA Polymerase II; Drug Carriers; Glycerol; Humans; Kinetics; Leukemia; Phorbol 12,13-Dibutyrate; Protein Binding; Protein Kinase C; Protein Kinases; RNA Polymerase II; Solvents; Tetradecanoylphorbol Acetate

1989
Differentiation of peanut lectin positive suppressor T-cells from peanut lectin negative precursors in bovine cells by 12-O-tetradecanoylphorbol-13-acetate.
    Cancer research, 1987, Jul-15, Volume: 47, Issue:14

    Topics: Animals; Cattle; Cell Differentiation; Cell Separation; Dose-Response Relationship, Drug; Drug Synergism; Lectins; Macrophages; Peanut Agglutinin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rosette Formation; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate

1987
Tumour-promoting phorbol esters inhibit agonist-induced phosphatidate formation and Ca2+ flux in human platelets.
    FEBS letters, 1985, Jan-28, Volume: 180, Issue:2

    Topics: Blood Platelets; Calcium; Carcinogens; Enzyme Activation; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylinositols; Platelet Activating Factor; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Thrombin; Vasopressins

1985
Structural requirements for diacylglycerols to mimic tumor-promoting phobol diester action on the epidermal growth factor receptor.
    The Journal of biological chemistry, 1985, May-10, Volume: 260, Issue:9

    Topics: Animals; Carcinogens; Cell Line; Diglycerides; ErbB Receptors; Glycerides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1985
Effects of tumor promoters on sodium ion transport across frog skin.
    The American journal of physiology, 1985, Volume: 248, Issue:5 Pt 1

    Topics: Amiloride; Animals; Biological Transport, Active; Carcinogens; Cyclic AMP; Indomethacin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Rana pipiens; Skin; Sodium; Tetradecanoylphorbol Acetate

1985
Effects of epidermal growth factor, phorbol myristate acetate, and arachidonic acid on choriogonadotropin secretion by cultured human choriocarcinoma cells.
    Endocrinology, 1985, Volume: 116, Issue:6

    Topics: Arachidonic Acid; Arachidonic Acids; Caenorhabditis elegans Proteins; Carrier Proteins; Catechols; Cells, Cultured; Choriocarcinoma; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Indomethacin; Masoprocol; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pregnancy; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Uterine Neoplasms

1985
Phorbol ester causes desensitization of gonadotropin-responsive adenylate cyclase in a murine Leydig tumor cell line.
    The Journal of biological chemistry, 1985, Jul-05, Volume: 260, Issue:13

    Topics: Adenylyl Cyclases; Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Chorionic Gonadotropin; Diglycerides; Dose-Response Relationship, Drug; Kinetics; Leydig Cell Tumor; Male; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Receptors, Immunologic; Receptors, LH; Testicular Neoplasms; Tetradecanoylphorbol Acetate

1985
Tumor-promoting phorbol esters and vanadate alter the sensitivity of HeLa S3 cells to poliovirus type 1.
    Experimental cell research, 1985, Volume: 160, Issue:1

    Topics: Cell Membrane; HeLa Cells; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Poliovirus; Tetradecanoylphorbol Acetate; Vanadates; Vanadium

1985
Induction of protein kinase C activation and Ca2+ mobilization by fibroblast growth factor in Swiss 3T3 cells.
    FEBS letters, 1985, Oct-28, Volume: 191, Issue:2

    Topics: Animals; Calcium; Cell Line; Diglycerides; DNA; Enzyme Activation; Fibroblast Growth Factors; Insulin; Mice; Mice, Inbred BALB C; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate

1985
Effect of the calcium ionophore A23187 on superoxide generation in phorbol ester stimulated human neutrophils.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:12

    Topics: Calcimycin; Calcium; Humans; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Lysosomes; Neutrophils; Oxygen Consumption; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Superoxides; Tetradecanoylphorbol Acetate

1985
Carbachol-induced accumulation of inositol-1-phosphate in neurohybridoma NCB-20 cells: effects of lithium and phorbol esters.
    Biochemical and biophysical research communications, 1986, Apr-29, Volume: 136, Issue:2

    Topics: Animals; Atropine; Benzodiazepinones; Brain; Carbachol; Cell Line; Chlorides; Cricetinae; Cricetulus; Embryo, Mammalian; Hybridomas; Inositol Phosphates; Lithium; Lithium Chloride; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pirenzepine; Sugar Phosphates; Tetradecanoylphorbol Acetate

1986
Inhibition of chemotactic peptide-induced phosphoinositide hydrolysis by phorbol esters through the activation of protein kinase C in differentiated human leukemia (HL-60) cells.
    Cancer research, 1986, Volume: 46, Issue:7

    Topics: Cell Differentiation; Cell Line; Enzyme Activation; Humans; Inositol Phosphates; Leukemia, Experimental; N-Formylmethionine Leucyl-Phenylalanine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Protein Kinase C; Sugar Phosphates; Tetradecanoylphorbol Acetate

1986
The effect of cAMP on tumour promoter responses mediated by C-kinase.
    Experimental cell research, 1986, Volume: 166, Issue:1

    Topics: Aminophylline; Animals; Bucladesine; Carcinogens; Cell Communication; Cell Line; Cyclic AMP; Diglycerides; Epidermal Growth Factor; Glycerides; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylcholines; Protein Kinase C; Tetradecanoylphorbol Acetate

1986
Action of retinoic acid on the diacylglycerol-induced ornithine decarboxylase activity, reduction in EGF binding and protein kinase C activation in rat tracheal epithelial 2C5 cells.
    Experimental cell research, 1986, Volume: 166, Issue:2

    Topics: Animals; Cell Line; Diglycerides; Enzyme Activation; Enzyme Induction; Epidermal Growth Factor; ErbB Receptors; Ornithine Decarboxylase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Trachea; Tretinoin

1986
Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst.
    The Journal of biological chemistry, 1986, Sep-25, Volume: 261, Issue:27

    Topics: Arachidonic Acid; Arachidonic Acids; Calcium; Cell Membrane; Cell Survival; Cytochrome c Group; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Zymosan

1986
Regulation of respiratory burst in murine peritoneal macrophages: differential sensitivity to phorbol diesters by macrophages in different states of functional activation.
    Cellular immunology, 1986, Volume: 100, Issue:2

    Topics: Animals; BCG Vaccine; Diglycerides; Dose-Response Relationship, Drug; Hydrogen Peroxide; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Oxygen Consumption; Phorbol 12,13-Dibutyrate; Phorbol Esters; Superoxides; Tetradecanoylphorbol Acetate; Zymosan

1986
Protein kinase C activators modulate differentiated thyroid function in vitro.
    FEBS letters, 1986, Oct-06, Volume: 206, Issue:2

    Topics: Animals; Bucladesine; Carcinogens; Enzyme Activation; Iodine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin

1986
Identification of a cell-surface glycoprotein mediating cell adhesion in EBV-immortalized normal B cells.
    International journal of cancer, 1986, Oct-15, Volume: 38, Issue:4

    Topics: Animals; Antibodies, Monoclonal; B-Lymphocytes; Cell Adhesion; Cell Aggregation; Cell Line; Fluorescent Antibody Technique; Glycoproteins; Herpesvirus 4, Human; Immunoglobulin Fab Fragments; Kinetics; Molecular Weight; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate

1986
Phorbol esters down-regulate protein kinase C in rat brain cerebral cortical slices.
    Biochemical and biophysical research communications, 1986, Aug-29, Volume: 139, Issue:1

    Topics: Animals; Cerebral Cortex; Cholera Toxin; Cyclic AMP; In Vitro Techniques; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylserines; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

1986
Effect of cellular fatty acid composition on the phospholipase A2 activity of bone marrow-derived macrophages, and their ability to induce lucigenin-dependent chemiluminescence.
    Biochimica et biophysica acta, 1986, Oct-31, Volume: 889, Issue:1

    Topics: Acridines; Animals; Bone Marrow Cells; Fatty Acids; Female; Luminescent Measurements; Macrophages; Membrane Lipids; Mice; Mice, Inbred C57BL; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phospholipases; Phospholipases A; Phospholipases A2; Superoxides; Tetradecanoylphorbol Acetate; Zymosan

1986
Inhibition of phorbol ester stimulated superoxide production by 1-oleoyl-2-acetyl-sn-glycerol (OAG); fact or artefact?
    FEBS letters, 1986, Dec-01, Volume: 209, Issue:1

    Topics: Animals; Brain; Cell Line; Cytosol; Diglycerides; Glycerides; Granulocytes; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Superoxides; Tetradecanoylphorbol Acetate

1986
Phorbol ester-induced inhibition of cyclic GMP formation mediated by muscarinic receptors in murine neuroblastoma cells.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Carbachol; Cell Line; Cyclic GMP; Dose-Response Relationship, Drug; Histamine; Isoquinolines; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Piperazines; Receptors, Muscarinic; Tetradecanoylphorbol Acetate

1987
Down-regulation of protein kinase C in rat glioma C6 cells: effects on the beta-adrenergic receptor-coupled adenylate cyclase.
    Biochemical and biophysical research communications, 1987, Apr-29, Volume: 144, Issue:2

    Topics: Adenylyl Cyclases; Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Line; Glioma; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate

1987
High- and low-affinity receptors regulate platelet responses to phorbol diesters and teleocidin.
    Thrombosis research, 1987, Mar-15, Volume: 45, Issue:6

    Topics: beta-Thromboglobulin; Binding, Competitive; Blood Platelets; Caenorhabditis elegans Proteins; Carrier Proteins; Chromatography, Gel; Humans; Lyngbya Toxins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Receptors, Immunologic; Serotonin; Tetradecanoylphorbol Acetate

1987
Possible involvement of reorganization of actin filaments, induced by tumor-promoting phorbol esters, in changes in colony shape and enhancement of proliferation of cultured epithelial cells.
    Journal of cellular physiology, 1987, Volume: 132, Issue:1

    Topics: Actins; Animals; Cell Division; Cyclic AMP; Diterpenes; Dogs; Epithelial Cells; Epithelium; Kidney; Microscopy, Fluorescence; Phorbol 12,13-Dibutyrate; Phorbol Esters; Terpenes; Tetradecanoylphorbol Acetate; Time Factors

1987
Defective production of reactive oxygen intermediates by tumor-associated macrophages exposed to phorbol ester.
    Journal of leukocyte biology, 1987, Volume: 42, Issue:1

    Topics: Animals; Macrophages; Male; Mice; Mice, Inbred C57BL; NADPH-Ferrihemoprotein Reductase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Sarcoma, Experimental; Superoxides; Tetradecanoylphorbol Acetate; Zymosan

1987
Induction of virus enzymes by phorbol esters and n-butyrate in Epstein-Barr virus genome-carrying Raji cells.
    Cancer research, 1987, Aug-15, Volume: 47, Issue:16

    Topics: Burkitt Lymphoma; Butyrates; Butyric Acid; Cells, Cultured; Deoxyribonucleases; DNA-Directed DNA Polymerase; DNA, Viral; Enzyme Induction; Genes, Viral; Herpesvirus 4, Human; Humans; Methylation; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Transcription, Genetic

1987
Second stage tumor promoters: differences in biological potency and phorbol ester receptor affinity in C6 cells.
    Cancer letters, 1987, Volume: 36, Issue:2

    Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Line; Cyclic AMP; Diterpenes; Glioma; Glycerolphosphate Dehydrogenase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Receptors, Drug; Receptors, Immunologic; Terpenes; Tetradecanoylphorbol Acetate

1987
Inhibition of DNA synthesis by protein kinase C-activating phorbol esters in NIH/3T3 cells.
    Journal of biochemistry, 1988, Volume: 104, Issue:1

    Topics: Animals; Cells, Cultured; DNA Replication; Enzyme Activation; Fibroblast Growth Factors; Insulin; Kinetics; Mice; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate

1988
Possible involvement of protein kinase C and calcium ion in growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts.
    The Journal of biological chemistry, 1986, Jan-25, Volume: 261, Issue:3

    Topics: Animals; Calcimycin; Calcium; Cell Line; Diglycerides; Enzyme Activation; Ethers; Fibroblast Growth Factors; Fibroblasts; Gene Expression Regulation; Ionomycin; Mice; Oncogenes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Platelet-Derived Growth Factor; Protein Kinase C; Tetradecanoylphorbol Acetate

1986
Activation of protein kinase C induces rapid internalization and subsequent degradation of muscarinic acetylcholine receptors in neuroblastoma cells.
    The Journal of biological chemistry, 1986, Apr-25, Volume: 261, Issue:12

    Topics: Animals; Calcimycin; Calcium; Carbachol; Cell Line; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Kinetics; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylserines; Protein Kinase C; Quinuclidinyl Benzilate; Receptors, Cholinergic; Tetradecanoylphorbol Acetate; Time Factors

1986
Phorbol ester-stimulated T lymphocytes show enhanced adhesion to human endothelial cell monolayers.
    Journal of immunology (Baltimore, Md. : 1950), 1986, Sep-01, Volume: 137, Issue:5

    Topics: Cell Adhesion; Cells, Cultured; Endothelium; Fibroblasts; Gelatin; Humans; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate; Umbilical Veins

1986
Dissociation of myosin phosphorylation and active tension during muscarinic stimulation of tracheal smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1

    Topics: Atropine; Calcium; Calcium Chloride; Carbachol; Dose-Response Relationship, Drug; Egtazic Acid; Muscle Contraction; Muscle, Smooth; Myosins; Nifedipine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Potassium; Serotonin; Tetradecanoylphorbol Acetate; Trachea

1987
Stimulation of epidermal growth factor receptor threonine 654 phosphorylation by platelet-derived growth factor in protein kinase C-deficient human fibroblasts.
    The Journal of biological chemistry, 1987, May-15, Volume: 262, Issue:14

    Topics: Carcinogens; Cell Line; ErbB Receptors; Fibroblasts; Humans; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Threonine

1987
Activation of protein kinase C is coupled to prostaglandin E2 synthesis in swine granulosa cells.
    Prostaglandins, 1987, Volume: 33, Issue:6

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Chromatography, High Pressure Liquid; Diglycerides; Dinoprostone; Drug Synergism; Enzyme Activation; Female; Follicle Stimulating Hormone; Gas Chromatography-Mass Spectrometry; Granulosa Cells; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate

1987
Juvenile hormone action mediated in male accessory glands of Drosophila by calcium and kinase C.
    Science (New York, N.Y.), 1988, Feb-19, Volume: 239, Issue:4842

    Topics: Animals; Calcium; Drosophila melanogaster; Enzyme Activation; Genitalia, Male; Juvenile Hormones; Male; Membrane Proteins; Mutation; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Biosynthesis; Protein Kinase C; Sesquiterpenes; Tetradecanoylphorbol Acetate

1988
The role of protein kinase C in LHRH-induced LH and FSH release and LHRH self-priming in rat anterior pituitary glands in vitro.
    The Journal of endocrinology, 1988, Volume: 116, Issue:2

    Topics: Animals; Enzyme Activation; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; In Vitro Techniques; Luteinizing Hormone; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Type C Phospholipases

1988
Tumor-promoting phorbol esters stimulate the proliferation of interleukin-3 dependent cells.
    Journal of cellular physiology, 1988, Volume: 137, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Cell Division; Cell Survival; Colony-Stimulating Factors; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Interleukin-3; Isoquinolines; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate

1988
Inhibition of protein kinase C by tamoxifen.
    Cancer research, 1985, Volume: 45, Issue:6

    Topics: Animals; Brain; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phospholipids; Protein Kinase C; Protein Kinase Inhibitors; Rats; Tamoxifen; Tetradecanoylphorbol Acetate

1985
Phorbolesters enhance basal D-glucose transport but inhibit insulin stimulation of D-glucose transport and insulin binding in isolated rat adipocytes.
    Biochemical and biophysical research communications, 1985, Apr-30, Volume: 128, Issue:2

    Topics: Adipose Tissue; Animals; Biological Transport, Active; Glucose; Insulin; Male; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Tetradecanoylphorbol Acetate

1985
Tumor-promoting phorbol esters induce rapid internalization of the C3b receptor via a cytoskeleton-dependent mechanism.
    Journal of immunology (Baltimore, Md. : 1950), 1985, Volume: 135, Issue:2

    Topics: Antibodies, Monoclonal; Binding, Competitive; Cytochalasin B; Cytoskeleton; Fibronectins; Humans; Immunoglobulin Fab Fragments; Neutrophils; Phagocytosis; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Receptors, Complement; Receptors, Complement 3b; Temperature; Tetradecanoylphorbol Acetate

1985
Suppression of nerve growth factor-directed neurite outgrowth in PC12 cells by sphingosine, an inhibitor of protein kinase C.
    The Journal of biological chemistry, 1988, Mar-25, Volume: 263, Issue:9

    Topics: Adrenal Gland Neoplasms; Animals; Cell Survival; Dose-Response Relationship, Drug; Nerve Growth Factors; Neurons; Pheochromocytoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; RNA, Messenger; Sphingosine; Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured

1988
Phorbol ester-induced stimulation of prostaglandin biosynthesis in human amnion cells.
    Biochimica et biophysica acta, 1988, Apr-15, Volume: 959, Issue:3

    Topics: Amnion; Dinoprostone; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Tetradecanoylphorbol Acetate

1988
Regulation of the epidermal growth factor receptor phosphorylation state by sphingosine in A431 human epidermoid carcinoma cells.
    The Journal of biological chemistry, 1988, Apr-15, Volume: 263, Issue:11

    Topics: Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; ErbB Receptors; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1988
Evidence for separate control by phorbol esters of CD18-dependent adhesion and translocation of protein kinase C in U-937 cells.
    Cancer research, 1988, Jun-01, Volume: 48, Issue:11

    Topics: Cell Adhesion; Cell Line; Choline; DNA Replication; Humans; Kinetics; Lipids; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate

1988
Phorbol esters stimulate the potassium-induced release of cholecystokinin from slices of cerebral cortex, caudato-putamen and hippocampus incubated in vitro.
    Biochemical and biophysical research communications, 1988, May-31, Volume: 153, Issue:1

    Topics: Animals; Caudate Nucleus; Cerebral Cortex; Cholecystokinin; Hippocampus; Male; Phorbol 12,13-Dibutyrate; Phorbol Esters; Potassium; Putamen; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1988
Characterization of lymphocyte stimulation by phorbol related compounds.
    Human toxicology, 1988, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Animals; Humans; Irritants; Lymphocyte Activation; Male; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phytohemagglutinins; Skin Tests; Tetradecanoylphorbol Acetate

1988
Correlation of the antiproliferative action of diphenylmethane-derivative antiestrogen binding site ligands with antagonism of histamine binding but not of protein kinase C-mediated phosphorylation.
    Cancer research, 1988, Jul-15, Volume: 48, Issue:14

    Topics: Animals; Benzhydryl Compounds; Cell Line; Cerebral Cortex; Dose-Response Relationship, Drug; Estrogen Antagonists; Histamine; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylethanolamines; Phosphorylation; Platelet Aggregation; Protein Kinase C; Rats; Receptors, Drug; Receptors, Estrogen; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1988
Schistosoma mansoni: evidence for protein kinase-C-like modulation of muscle activity.
    Experimental parasitology, 1988, Volume: 66, Issue:2

    Topics: Animals; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Activation; Male; Movement; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Schistosoma mansoni; Tetradecanoylphorbol Acetate

1988
Growth-dependent subcellular redistribution of protein kinase C in cultured porcine aortic endothelial cells.
    Journal of cellular physiology, 1988, Volume: 136, Issue:3

    Topics: Animals; Cell Division; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Phorbol 12,13-Dibutyrate; Protein Kinase C; Subcellular Fractions; Swine; Tetradecanoylphorbol Acetate

1988
Phorbol ester receptors and the induction of differentiation in the human T lymphoblastic cell line MOLT-3.
    Experimental cell biology, 1988, Volume: 56, Issue:1-2

    Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Differentiation; Cell Line, Transformed; Cell Transformation, Neoplastic; Drug Resistance; Humans; Leukemia-Lymphoma, Adult T-Cell; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Drug; Statistics as Topic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988
Interleukin 3 stimulates proliferation via protein kinase C activation without increasing inositol lipid turnover.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:10

    Topics: Caenorhabditis elegans Proteins; Calcium; Carcinogens; Carrier Proteins; Cell Line; Cell Survival; DNA Replication; Enzyme Activation; Inositol; Interleukin-3; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Protein Kinase C; Receptors, Drug; Tetradecanoylphorbol Acetate

1988
Activation and proliferation signals in mouse B cells. IX. Protein kinase C activators synergize with non-mitogenic anti-immunoglobulin antibodies to drive B cells into G1.
    Immunology, 1988, Volume: 64, Issue:1

    Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Calcium; Cyclosporins; Enzyme Activation; Immunoglobulin Fab Fragments; Immunoglobulin G; Interphase; Lymphocyte Activation; Male; Mice; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate

1988
Phorbol esters can persistently replace interleukin-2 (IL-2) for the growth of a human IL-2-dependent T-cell line.
    Journal of cellular physiology, 1988, Volume: 136, Issue:2

    Topics: Cell Line; Humans; Interleukin-2; Nucleic Acid Hybridization; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate

1988
Effect of protein kinase C activation and depletion on insulin stimulation of glycogen synthesis in cultured hepatoma cells.
    Experientia, 1988, Jan-15, Volume: 44, Issue:1

    Topics: Animals; Enzyme Activation; Glycogen; Insulin; Liver Neoplasms, Experimental; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988
Generation of neutrophil chemotactic activity by phorbol ester-stimulated calf pulmonary artery endothelial cells.
    Journal of leukocyte biology, 1988, Volume: 44, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Chemotactic Factors; Culture Media; Dactinomycin; Endothelium, Vascular; Interleukin-8; Neutrophils; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pulmonary Artery; Tetradecanoylphorbol Acetate

1988
Dioctanoylglycerol and phorbol esters regulate transcription of c-myc in human promyelocytic leukemia cells.
    The Journal of biological chemistry, 1988, Feb-05, Volume: 263, Issue:4

    Topics: Diglycerides; Enzyme Activation; Glycerides; Humans; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1988
Tumor promoter-induced membrane-bound protein kinase C regulates hematogenous metastasis.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:2

    Topics: Animals; Carcinogens; Cell Line; Cell Membrane; Cytosol; Enzyme Induction; Kinetics; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate

1988
Protein kinase C and phorbol ester receptor expression related to growth and differentiation of nullipotent and pluripotent embryonal carcinoma cells.
    Developmental biology, 1986, Volume: 115, Issue:2

    Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Differentiation; Cell Division; Cell Line; DNA Replication; Kinetics; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Teratoma; Tetradecanoylphorbol Acetate; Thymidine

1986
Phorbol esters inhibit the proliferation of MCF-7 cells. Possible implication of protein kinase C.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Breast Neoplasms; Cell Division; Cell Line; Dose-Response Relationship, Drug; Female; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Tetradecanoylphorbol Acetate

1986
Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases.
    The Journal of biological chemistry, 1986, Sep-25, Volume: 261, Issue:27

    Topics: Acid Phosphatase; Binding, Competitive; Cell Adhesion; Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Sphingosine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1986
Endogenous inhibitor of protein kinase C: association with human peripheral blood neutrophils but not with specific granule-deficient neutrophils or cytoplasts.
    Journal of immunology (Baltimore, Md. : 1950), 1986, Sep-01, Volume: 137, Issue:5

    Topics: Cytoplasmic Granules; Diglycerides; Humans; Intracellular Membranes; Neutrophils; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate

1986
Phorbol ester-induced contraction in chemically skinned vascular smooth muscle.
    The American journal of physiology, 1986, Volume: 251, Issue:3 Pt 1

    Topics: Animals; Calcium; Carotid Arteries; Enzyme Activation; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Myosins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Potassium; Protein Kinase C; Skin Physiological Phenomena; Swine; Tetradecanoylphorbol Acetate

1986
Phorbol diesters alter the contractile responses of porcine coronary artery.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1

    Topics: Animals; Calcium; Drug Synergism; Histamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Polymyxin B; Potassium; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate

1986
Effects of tumor promoters on LLC-PK1 renal epithelial tight junctions and transepithelial fluxes.
    The American journal of physiology, 1986, Volume: 251, Issue:4 Pt 1

    Topics: Carcinogens; Cell Line; Diffusion; Epithelium; Intercellular Junctions; Kidney; Membrane Potentials; Phorbol 12,13-Dibutyrate; Phorbol Esters; Sodium Chloride; Tetradecanoylphorbol Acetate

1986
Factors influencing chelator-stable, detergent-extractable, phorbol diester-induced membrane association of protein kinase C. Differences between Ca2+-induced and phorbol ester-stabilized membrane bindings of protein kinase C.
    The Journal of biological chemistry, 1986, Dec-15, Volume: 261, Issue:35

    Topics: Animals; Calcium; Calcium Chloride; Cell Line; Cell Membrane; Cells, Cultured; Detergents; Diglycerides; Glycerides; Organoids; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phospholipases; Protein Binding; Protein Kinase C; Tetradecanoylphorbol Acetate; Trypsin

1986
Three activators of protein kinase C, bryostatins, dioleins, and phorbol esters, show differing specificities of action on GH4 pituitary cells.
    The Journal of biological chemistry, 1986, Dec-25, Volume: 261, Issue:36

    Topics: Animals; Binding Sites; Binding, Competitive; Bryostatins; Cell Line; Diglycerides; Enzyme Activation; Eukaryota; Glycerides; Kinetics; Lactones; Macrolides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pituitary Neoplasms; Protein Kinase C; Tetradecanoylphorbol Acetate

1986
Possible involvement of protein kinase C in platelet-derived growth factor-stimulated DNA synthesis in vascular smooth muscle cells.
    Atherosclerosis, 1987, Volume: 63, Issue:2-3

    Topics: Animals; Cell Division; Cells, Cultured; DNA; Enzyme Activation; Humans; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Phorbol Esters; Platelet-Derived Growth Factor; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate

1987
Down regulation of protein kinase C in neuronal cells: effects on neurotransmitter release.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1987, Volume: 7, Issue:4

    Topics: Animals; Cells, Cultured; Ethers; Ionomycin; Neurons; Nitrendipine; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Sympathetic Nervous System; Tetradecanoylphorbol Acetate

1987
Catalytic and receptor-binding properties of the calcium-sensitive phospholipid-dependent protein kinase (protein kinase C) in swine luteal cytosol.
    Molecular and cellular endocrinology, 1987, Volume: 50, Issue:1-2

    Topics: Animals; Caenorhabditis elegans Proteins; Calcium; Carrier Proteins; Corpus Luteum; Cytosol; Diglycerides; Enzyme Activation; Female; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylserines; Polymyxin B; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Swine; Tetradecanoylphorbol Acetate

1987
Phorbol esters inhibit ammoniagenesis and gluconeogenesis in proximal tubular segments.
    The American journal of physiology, 1987, Volume: 252, Issue:6 Pt 2

    Topics: Ammonia; Animals; Dimethyl Sulfoxide; Dogs; Gluconeogenesis; Glutamine; Kidney Tubules, Proximal; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1987
Substitution of phosphatidylserine by lipid A in the activation of purified rabbit brain protein kinase C.
    FEBS letters, 1987, Jun-29, Volume: 218, Issue:2

    Topics: Animals; Brain; Enzyme Activation; Lipid A; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylserines; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate

1987
Distinct functions of down-regulation-sensitive and -resistant types of protein kinase C in rabbit aortic smooth muscle cells.
    FEBS letters, 1987, Jul-13, Volume: 219, Issue:1

    Topics: Animals; Aorta, Thoracic; Calcium; Cytoplasm; DNA; Drug Resistance; Male; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate

1987
Divergent effects of co-carcinogenic phorbol esters and a synthetic diacylglycerol on human neutrophil chemokinesis and granular enzyme secretion.
    British journal of pharmacology, 1987, Volume: 91, Issue:3

    Topics: Calcium; Chemotaxis, Leukocyte; Cocarcinogenesis; Cytoplasmic Granules; Diglycerides; Glycerides; Humans; Muramidase; Neutrophils; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate

1987
TPA induces subcellular translocation and subsequent down-regulation of both phorbol ester binding and protein kinase C activities in MCF-7 cells.
    Biochemical and biophysical research communications, 1987, Jul-31, Volume: 146, Issue:2

    Topics: Animals; Binding Sites; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors

1987
Differences between human and goose erythrocytes in response to phorbol esters and expression of phorbol ester receptors.
    Cancer research, 1987, Sep-15, Volume: 47, Issue:18

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Erythrocytes; Geese; Glucosamine; Humans; Oxadiazoles; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Species Specificity; Temperature; Tetradecanoylphorbol Acetate

1987
Phorbol myristate acetate inhibits growth in S49 cells: isolation of resistant variants.
    Journal of cellular physiology, 1987, Volume: 132, Issue:3

    Topics: Animals; Cell Division; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Lymphoma; Mice; Molecular Weight; Ornithine Decarboxylase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1987
4 beta-PDBu contracts parenchymal strip and synergizes with raised cytosolic calcium.
    European journal of pharmacology, 1987, Sep-02, Volume: 141, Issue:1

    Topics: Animals; Calcium; Cytosol; Dimethyl Sulfoxide; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate

1987
Purification and characterization of calcium/phospholipid-dependent kinase from adult human epidermis.
    The Journal of investigative dermatology, 1987, Volume: 89, Issue:5

    Topics: Adult; Caenorhabditis elegans Proteins; Calcium; Carrier Proteins; Cell Membrane; Cytosol; Diglycerides; Epidermis; Humans; Membrane Proteins; Molecular Weight; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylserines; Protein Kinase C; Receptors, Drug; Tetradecanoylphorbol Acetate

1987
1,2-Diacylglycerols but not phorbol esters stimulate sphingomyelin hydrolysis in GH3 pituitary cells.
    The Journal of biological chemistry, 1987, Dec-15, Volume: 262, Issue:35

    Topics: Animals; Ceramides; Choline; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Glycerides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pituitary Neoplasms; Rats; Sphingomyelin Phosphodiesterase; Sphingomyelins; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1987
Phorbol-ester-induced alterations of free calcium ion transients in single rat hepatocytes.
    The Biochemical journal, 1987, Sep-15, Volume: 246, Issue:3

    Topics: Aequorin; Animals; Arginine Vasopressin; Biological Transport; Calcium; In Vitro Techniques; Liver; Male; Phenylephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1987
Comparison of the activity of phorbol 12-myristate 13-acetate and the diglyceride glycerol 1-myristate 2-acetate.
    Carcinogenesis, 1986, Volume: 7, Issue:4

    Topics: Animals; Cell Line; Diglycerides; Epidermal Growth Factor; Fibroblasts; Glycerides; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Tetradecanoylphorbol Acetate

1986
Antagonistic effects of phorbol esters on lymphocyte activation. Evidence that protein kinase C provides an early signal associated with lytic function.
    The Journal of biological chemistry, 1986, Sep-25, Volume: 261, Issue:27

    Topics: Animals; Cell Line; Kinetics; Lymphocyte Activation; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate

1986
Altered protein kinase C in a mast cell variant defective in exocytosis.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:5

    Topics: Animals; Caenorhabditis elegans Proteins; Calcium; Carrier Proteins; Cell Line; Exocytosis; Genetic Variation; Interleukin-3; Mast Cells; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Serotonin; Tetradecanoylphorbol Acetate

1987
Inhibition of DNA synthesis by phorbol esters through protein kinase C in cultured rabbit aortic smooth muscle cells.
    FEBS letters, 1987, Jun-08, Volume: 217, Issue:1

    Topics: Animals; Aorta, Thoracic; Cells, Cultured; DNA Replication; Epidermal Growth Factor; Male; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Phorbol Esters; Platelet-Derived Growth Factor; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate

1987
Perturbation of cultured human vascular endothelial cells by phorbol ester or thrombin alters the cellular von Willebrand factor distribution.
    Journal of cellular physiology, 1987, Volume: 133, Issue:1

    Topics: Cells, Cultured; Endothelium, Vascular; Extracellular Matrix; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; RNA, Messenger; Subcellular Fractions; Tetradecanoylphorbol Acetate; Thrombin; von Willebrand Factor

1987
Synergistic interaction between interleukin 4 and anti-Bp50 (CDw40) revealed in a novel B cell restimulation assay.
    European journal of immunology, 1987, Volume: 17, Issue:10

    Topics: Antibodies, Monoclonal; Antigens, Differentiation; B-Lymphocytes; DNA; Ethers; Humans; Interleukin-4; Interleukins; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate

1987
Protein kinase C-mediated feed back inhibition of the Ca2+ response at the EGF receptor.
    Biochemical and biophysical research communications, 1987, Nov-30, Volume: 149, Issue:1

    Topics: Calcium; Carcinoma, Squamous Cell; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Feedback; Inositol Phosphates; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1987
Phorbol ester-stimulated phosphorylation of basolateral membranes from canine kidney.
    The American journal of physiology, 1986, Volume: 250, Issue:6 Pt 2

    Topics: Adenosine Triphosphate; alpha-Glucosidases; Amino Acids; Animals; Dogs; In Vitro Techniques; Kidney; Membranes; Microvilli; Osmolar Concentration; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phospholipids; Phosphorylation; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tritium

1986
Quantitation of protein kinase C by immunoblot--expression in different cell lines and response to phorbol esters.
    Journal of cellular physiology, 1987, Volume: 130, Issue:1

    Topics: Animals; Antigen-Antibody Complex; Cattle; Cell Line; Glioma; Humans; Immunologic Techniques; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rabbits; Rats; Tetradecanoylphorbol Acetate

1987
Phorbol esters increase calcitonin gene transcription and decrease c-myc mRNA levels in cultured human medullary thyroid carcinoma.
    The Journal of biological chemistry, 1985, Jan-10, Volume: 260, Issue:1

    Topics: Calcitonin; Carcinogens; Cell Line; DNA; Genes; Humans; Kinetics; Oncogenes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; RNA, Messenger; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Transcription, Genetic

1985
Comparative effects of a complete tumor promoter, TPA, and a second-stage tumor promoter, RPA, on intercellular communication, cell differentiation and cell transformation.
    Carcinogenesis, 1985, Volume: 6, Issue:8

    Topics: Animals; Cell Communication; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Mice; Mice, Inbred BALB C; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1985
Characterization of the growth inhibition induced by tumor-promoting phorbol esters and of their receptor binding in A549 human lung carcinoma cells.
    Cancer research, 1985, Volume: 45, Issue:9

    Topics: Caenorhabditis elegans Proteins; Carcinoma; Carrier Proteins; Cell Division; Cells, Cultured; Humans; Lung Neoplasms; Male; Middle Aged; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tritium; Type C Phospholipases

1985
Glucocorticoid-mediated increases in glycerol phosphate dehydrogenase activity is inhibited by the phorbol ester tumor promoters.
    Journal of neurochemistry, 1985, Volume: 45, Issue:4

    Topics: Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Dexamethasone; Enzyme Induction; Glioma; Glycerolphosphate Dehydrogenase; Oligodendroglia; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Rats; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Theophylline

1985
Induction and desensitization of plasminogen activator gene expression by tumor promoters.
    The Journal of biological chemistry, 1985, Oct-15, Volume: 260, Issue:23

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcitonin; Carcinogens; Cell Line; Cycloheximide; Dexamethasone; Diterpenes; Dose-Response Relationship, Drug; Enzyme Induction; Gene Expression Regulation; Kidney; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; RNA, Messenger; Swine; Terpenes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Urokinase-Type Plasminogen Activator

1985
Cellular uptake and localization of fluorescent derivatives of phorbol ester tumor promoters.
    Biochemical and biophysical research communications, 1985, Sep-16, Volume: 131, Issue:2

    Topics: Animals; Binding, Competitive; Cattle; Cell Line; Chick Embryo; Cytoplasm; Dansyl Compounds; Enzyme Activation; Fluorescent Dyes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1985
Effects of 6-thioguanine on communication competence and factors affecting reversibility of phorbol ester inhibition in V79 cells measured by the metabolic cooperation assay and by dye coupling.
    Carcinogenesis, 1985, Volume: 6, Issue:11

    Topics: Animals; Cell Communication; Cells, Cultured; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Hypoxanthine Phosphoribosyltransferase; Isoquinolines; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate; Thioguanine

1985
The 65-kDa phorbol-diester hydrolase in mouse plasma is esterase 1 and is immunologically distinct from the 56-kDa phorbol-diester hydrolase in mouse liver.
    The Journal of biological chemistry, 1985, Dec-15, Volume: 260, Issue:29

    Topics: Animals; Antibody Specificity; Carboxylesterase; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Cross Reactions; Estradiol; Kinetics; Liver; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1985
Role of phorbol ester receptors in the 12-0-tetradecanoyl-phorbol-13-acetate (TPA)-induced down-regulation of colony-stimulating factor (CSF-1) binding to murine peritoneal exudate macrophages.
    Journal of cellular physiology, 1985, Volume: 124, Issue:2

    Topics: Animals; Ascitic Fluid; Caenorhabditis elegans Proteins; Carrier Proteins; Colony-Stimulating Factors; Macrophages; Mice; Mice, Inbred C3H; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Temperature; Tetradecanoylphorbol Acetate; Time Factors

1985
Sensitization of frog erythrocyte adenylate cyclase system by tumor-promoting phorbol diesters.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:8

    Topics: Adenylyl Cyclases; Animals; Carcinogens; Erythrocyte Membrane; Erythrocytes; Fluorides; Isoproterenol; Kinetics; Manganese; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Rana pipiens; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1985
Bryostatins: potent, new mitogens that mimic phorbol ester tumor promoters.
    Biochemical and biophysical research communications, 1985, Nov-15, Volume: 132, Issue:3

    Topics: Animals; Bryostatins; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cells, Cultured; Insulin; Lactones; Macrolides; Mice; Mitogens; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thymidine

1985
Effects of phorbol myristate acetate, phorbol dibutyrate, ethanol, dimethylsulfoxide, phenol, and seven metabolites of phenol on metabolic cooperation between Chinese hamster V79 lung fibroblasts.
    Cell biology and toxicology, 1985, Volume: 1, Issue:4

    Topics: Animals; Carcinogens; Cell Communication; Cells, Cultured; Cricetinae; Cricetulus; Dimethyl Sulfoxide; Ethanol; Fibroblasts; Lung; Phenol; Phenols; Phorbol 12,13-Dibutyrate; Tetradecanoylphorbol Acetate

1985
Reversibility of phorbol diester-induced macrophage spreading.
    Cell biology and toxicology, 1985, Volume: 1, Issue:4

    Topics: Animals; Female; Macrophages; Mice; Mice, Inbred ICR; Phorbol 12,13-Dibutyrate; Tetradecanoylphorbol Acetate

1985
gamma-Interferon enhances the secretion of arachidonic acid metabolites from murine peritoneal macrophages stimulated with phorbol diesters.
    Journal of immunology (Baltimore, Md. : 1950), 1985, Volume: 134, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Arachidonic Acid; Arachidonic Acids; Interferon-gamma; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Prostaglandins; SRS-A; Tetradecanoylphorbol Acetate; Thromboxane B2

1985
Similar effects of phospholipase C and phorbol ester tumor promoters on primary mouse epidermal cells.
    Cancer research, 1985, Volume: 45, Issue:11 Pt 2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Caenorhabditis elegans Proteins; Carrier Proteins; Cells, Cultured; Diglycerides; Enzyme Induction; Epidermal Growth Factor; Epidermis; Mice; Mice, Inbred BALB C; Ornithine Decarboxylase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tritium; Type C Phospholipases

1985
Inhibition of cell communication between Balb/c 3T3 cells by tumor promoters and protection by cAMP.
    Journal of cellular physiology, 1984, Volume: 121, Issue:2

    Topics: Animals; Bucladesine; Caenorhabditis elegans Proteins; Caffeine; Carcinogens; Carrier Proteins; Cell Communication; Cells, Cultured; Cricetinae; Cricetulus; Cyclic AMP; Fluorescent Dyes; Isoquinolines; Lung; Mice; Mice, Inbred BALB C; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate

1984
Biological responsiveness to the phorbol esters and specific binding of [3H]phorbol 12,13-dibutyrate in the nematode Caenorhabditis elegans, a manipulable genetic system.
    Teratogenesis, carcinogenesis, and mutagenesis, 1982, Volume: 2, Issue:1

    Topics: Animals; Caenorhabditis; Carcinogens; Movement; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tritium

1982
Tumour promoter-mediated reversible inhibition of cell-cell communication (electrical coupling). Relationship with phorbol ester binding and de novo macromolecule synthesis.
    Experimental cell research, 1983, Volume: 146, Issue:2

    Topics: Binding Sites; Cell Communication; Cell Line; Cycloheximide; Dactinomycin; Diterpenes; Electrophysiology; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Biosynthesis; RNA; Terpenes; Tetradecanoylphorbol Acetate

1983
Activation of protein kinase C by non-phorbol tumor promoter, mezerein.
    Biochemical and biophysical research communications, 1984, Jun-15, Volume: 121, Issue:2

    Topics: Animals; Brain; Carcinogens; Diterpenes; Enzyme Activation; Humans; In Vitro Techniques; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phospholipids; Protein Binding; Protein Kinase C; Protein Kinases; Rats; Structure-Activity Relationship; Terpenes; Tetradecanoylphorbol Acetate

1984
Phorbol ester stimulation of Na influx and Na-K pump activity in Swiss 3T3 cells.
    Biochemical and biophysical research communications, 1981, May-15, Volume: 100, Issue:1

    Topics: Animals; Biological Transport, Active; Carcinogens; Cells, Cultured; Kinetics; Mice; Mice, Inbred Strains; Monensin; Ouabain; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Rubidium; Sodium; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate

1981
Inhibition of epidermal growth factor binding to mouse embryonal carcinoma cells by phorbol esters mediated by specific phorbol ester receptors.
    The Journal of biological chemistry, 1981, Aug-10, Volume: 256, Issue:15

    Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Line; Epidermal Growth Factor; ErbB Receptors; Kinetics; Mice; Neoplasms, Experimental; Peptides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Teratoma; Tetradecanoylphorbol Acetate

1981
Tumor promoter binding to rat mammary cell cultures: role of receptors in the inhibition of dome formation.
    Cancer research, 1983, Volume: 43, Issue:3

    Topics: Animals; Binding, Competitive; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Female; Mammary Neoplasms, Experimental; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Rats; Receptors, Cell Surface; Receptors, Drug; Temperature; Tetradecanoylphorbol Acetate; Time Factors

1983
Specific desensitization to tumor-promoting phorbol esters in mouse pituitary cells. Evidence that desensitization is a two-step process.
    The Journal of biological chemistry, 1983, Mar-10, Volume: 258, Issue:5

    Topics: Adrenocorticotropic Hormone; Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Kinetics; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pituitary Neoplasms; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Tetradecanoylphorbol Acetate

1983
Control of endogenous cell regulators by the second-stage tumor promoter phorbol-12-retinoate 13-acetate.
    International journal of cancer, 1983, Apr-15, Volume: 31, Issue:4

    Topics: Animals; Binding, Competitive; Cell Differentiation; Cells, Cultured; Cyclic AMP; Glycoproteins; Growth Inhibitors; Interleukin-6; Leukemia Inhibitory Factor; Leukemia, Myeloid; Lymphokines; Mice; Muramidase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate

1983
Binding of phorbol dibutyrate and epidermal growth factor to cultured human epidermal cells.
    Journal of the National Cancer Institute, 1983, Volume: 70, Issue:3

    Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; Melanoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Skin Neoplasms; Tetradecanoylphorbol Acetate

1983
Characterization of a high-affinity receptor for phorbol esters in rat alveolar macrophages.
    Inflammation, 1983, Volume: 7, Issue:1

    Topics: Animals; Binding, Competitive; Caenorhabditis elegans Proteins; Carrier Proteins; Kinetics; Macrophages; Male; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Pulmonary Alveoli; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Tetradecanoylphorbol Acetate

1983
The role of phorbol ester receptor binding in responses to promoters by mouse and human cells.
    Basic life sciences, 1983, Volume: 24

    Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Differentiation; Cell Line; Clone Cells; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Skin; Tetradecanoylphorbol Acetate

1983
An inhibitory effect of tumour promoters on human epithelial cell growth can be dissociated from an effect on junctional communication.
    Experimental cell research, 1983, Volume: 145, Issue:2

    Topics: Breast Neoplasms; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Communication; Cell Division; Cell Line; Cell Transformation, Viral; Epidermal Cells; Epidermis; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Tetradecanoylphorbol Acetate

1983
Tumor-promoting phorbol esters inhibit the binding of colony-stimulating factor (CSF-1) to murine peritoneal exudate macrophages.
    Journal of cellular physiology, 1983, Volume: 116, Issue:2

    Topics: Animals; Ascitic Fluid; Colony-Stimulating Factors; Dose-Response Relationship, Drug; Kinetics; Macrophages; Mice; Mice, Inbred C3H; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Receptors, Cell Surface; Receptors, Colony-Stimulating Factor; Temperature; Tetradecanoylphorbol Acetate

1983
Antagonist of phorbol ester receptor-mediated chemotaxis in mouse peritoneal macrophages.
    Cancer research, 1983, Volume: 43, Issue:10

    Topics: Animals; Ascitic Fluid; Binding, Competitive; Caenorhabditis elegans Proteins; Carrier Proteins; Chemotaxis; Female; Macrophages; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Tetradecanoylphorbol Acetate; Time Factors

1983
Phorbol diester-induced H2O2 production by peritoneal macrophages. Different H2O2 production by macrophages from normal and BCG-infected mice despite comparable phorbol diester receptors.
    Cellular immunology, 1983, Volume: 80, Issue:2

    Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cells, Cultured; Female; Hydrogen Peroxide; Kinetics; Macrophages; Mice; Mice, Inbred Strains; Mycobacterium bovis; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Tetradecanoylphorbol Acetate

1983
Epidermal growth factor and potent phorbol tumor promoters induce epidermal growth factor receptor phosphorylation in a similar but distinctively different manner in human epidermoid carcinoma A431 cells.
    The Journal of biological chemistry, 1984, Feb-25, Volume: 259, Issue:4

    Topics: Carcinogens; Carcinoma, Squamous Cell; Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphorylation; Receptors, Cell Surface; Tetradecanoylphorbol Acetate

1984
Possible mechanism of phorbol diester-induced maturation of human promyelocytic leukemia cells.
    The Journal of clinical investigation, 1984, Volume: 73, Issue:2

    Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Differentiation; Cell Line; Enzyme Activation; Humans; Leukemia, Myeloid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Receptors, Drug; Tetradecanoylphorbol Acetate

1984
Vinculin phosphorylation in response to calcium and phorbol esters in intact cells.
    The Journal of biological chemistry, 1984, Apr-25, Volume: 259, Issue:8

    Topics: Animals; Bucladesine; Calcium; Cells, Cultured; Chick Embryo; Dibutyryl Cyclic GMP; Fibroblasts; Kinetics; Mice; Muscle Proteins; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphopeptides; Phosphorylation; Tetradecanoylphorbol Acetate; Trypsin; Vinculin

1984
Communication between receptors for different ligands on a single cell: ligation of fibronectin receptors induces a reversible alteration in the function of complement receptors on cultured human monocytes.
    The Journal of cell biology, 1984, Volume: 99, Issue:1 Pt 1

    Topics: Cell Communication; Fibronectins; Humans; Macrophage-1 Antigen; Monocytes; Phagocytosis; Phorbol 12,13-Dibutyrate; Phorbol Esters; Receptors, Cell Surface; Receptors, Complement; Receptors, Fibronectin; Serum Albumin; Tetradecanoylphorbol Acetate

1984
Phorbol esters rapidly stimulate amiloride-sensitive Na+/H+ exchange in a human leukemic cell line.
    The Journal of cell biology, 1984, Volume: 99, Issue:1 Pt 1

    Topics: Amiloride; Carrier Proteins; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pyrazines; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate

1984
Analysis of human promyelocytic leukemia cell (HL60) variants insensitive to phorbol ester tumor promoters.
    Cancer research, 1984, Volume: 44, Issue:8

    Topics: Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Line; Genetic Variation; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Superoxide Dismutase; Tetradecanoylphorbol Acetate

1984
Phorbol esters inhibit murine B cell differentiation to immunoglobulin secretion but not proliferation.
    Journal of immunology (Baltimore, Md. : 1950), 1984, Volume: 133, Issue:4

    Topics: Animals; Antibody-Producing Cells; B-Lymphocytes; Cell Differentiation; Dose-Response Relationship, Immunologic; Female; Immunoglobulin G; Immunoglobulin M; Immunosuppressive Agents; Kinetics; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1984
Phorbol diesters stimulate somatostatin secretion from cultured brain cells.
    Endocrinology, 1983, Volume: 113, Issue:1

    Topics: Alkaloids; Animals; Cell Line; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Hypothalamus; Lyngbya Toxins; Peptides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pregnancy; Rats; Tetradecanoylphorbol Acetate; Verapamil

1983
Teleocidin-induced phenotypic changes in thymic ALL cell line, HPB-ALL.
    Oncology, 1983, Volume: 40, Issue:4

    Topics: Adolescent; Alkaloids; Binding, Competitive; Carcinogens; Cell Differentiation; Cell Line; DNA; Humans; Leukemia, Lymphoid; Lyngbya Toxins; Male; Phenotype; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rosette Formation; Tetradecanoylphorbol Acetate

1983
Presence of specific binding sites for phorbol ester tumor promoters in human epidermal and dermal cells in culture but lack of down regulation in epidermal cells.
    Cancer research, 1983, Volume: 43, Issue:8

    Topics: Binding Sites; Binding, Competitive; Cells, Cultured; Diterpenes; Epidermis; Humans; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Terpenes; Tetradecanoylphorbol Acetate

1983
Control of macrophage cell differentiation in human promyelocytic HL-60 leukemia cells by 1,25-dihydroxyvitamin D3 and phorbol-12-myristate-13-acetate.
    Cancer research, 1983, Volume: 43, Issue:10

    Topics: Antibodies, Monoclonal; Calcitriol; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Macrophages; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1983
Phorbol ester-associated changes in ganglioside metabolism.
    Experimental cell research, 1983, Volume: 147, Issue:2

    Topics: Animals; Carcinogens; Cell Division; Cell Line; Contact Inhibition; Cricetinae; Gangliosides; Palmitic Acid; Palmitic Acids; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Sialic Acids; Sialyltransferases; Tetradecanoylphorbol Acetate

1983
Phorbol 12,13-dibutyrate enhances lateral redistribution of membrane glycoproteins in human blood lymphocytes.
    European journal of immunology, 1984, Volume: 14, Issue:9

    Topics: Glycoproteins; Humans; Immunologic Capping; Lymphocytes; Membrane Proteins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protease Inhibitors; Tetradecanoylphorbol Acetate

1984
Inhibition of denuded mouse oocyte meiotic maturation by tumor-promoting phorbol esters and its reversal by retinoids.
    Experimental cell research, 1984, Volume: 154, Issue:2

    Topics: Animals; Colforsin; Diterpenes; Drug Interactions; Female; Meiosis; Mice; Oocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Retinoids; Tetradecanoylphorbol Acetate

1984
Phorbol esters inhibit agonist-induced [3H] inositol-1-phosphate accumulation in rat hippocampal slices.
    Biochemical and biophysical research communications, 1984, Sep-17, Volume: 123, Issue:2

    Topics: Animals; Caenorhabditis elegans Proteins; Carbachol; Carcinogens; Carrier Proteins; Hippocampus; Inositol; Inositol Phosphates; Male; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Rats; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate

1984
Biological activity of a fluorescent 12-O-tetradecanoyl-phorbol-13-acetate derivative.
    Gan, 1984, Volume: 75, Issue:9

    Topics: Animals; Cricetinae; Cricetulus; Dansyl Compounds; Fluorescence; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1984
Phorbol ester tumor promoters specifically stimulate choline phospholipid metabolism in human leukemic cells.
    Biochimica et biophysica acta, 1984, Dec-06, Volume: 796, Issue:3

    Topics: Acetates; Acetic Acid; Caenorhabditis elegans Proteins; Carbon Radioisotopes; Carcinogens; Carrier Proteins; Cells, Cultured; Choline; Humans; Leukemia, Hairy Cell; Microscopy, Electron, Scanning; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylcholines; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tritium

1984
Relationship between mezerein-mediated biological responses and phorbol ester receptor occupancy.
    Cancer research, 1983, Volume: 43, Issue:1

    Topics: Binding, Competitive; Caenorhabditis elegans Proteins; Carrier Proteins; Dinoprostone; Diterpenes; Epidermal Growth Factor; Humans; Kinetics; Osteosarcoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Prostaglandins E; Protein Kinase C; Receptors, Drug; Terpenes; Tetradecanoylphorbol Acetate

1983
The tumor promoter phorbol-12,13-dibutyrate [P(Bu)2] stimulates cytotoxic activity of human blood lymphocytes.
    Immunobiology, 1983, Volume: 165, Issue:5

    Topics: Cell Adhesion; Cytotoxicity, Immunologic; Humans; In Vitro Techniques; Killer Cells, Natural; Lymphocyte Activation; Lymphocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Time Factors

1983
The control of phospholipid methylation by phorbol diesters in differentiating human myeloid HL-60 leukemia cells.
    Carcinogenesis, 1982, Volume: 3, Issue:8

    Topics: Alkaloids; Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid, Acute; Lyngbya Toxins; Methylation; Methyltransferases; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Tetradecanoylphorbol Acetate

1982
Down regulation of specific binding of [20-3H]phorbol 12,13-dibutyrate and phorbol ester-induced differentiation of human promyelocytic leukemia cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:3

    Topics: Binding Sites; Binding, Competitive; Carcinogens; Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1981
TPA-resistance in Friend erythroleukemia cells: role of membrane lipid fluidity.
    Biochemical and biophysical research communications, 1981, May-15, Volume: 100, Issue:1

    Topics: Animals; Carcinogens; Cell Line; Clone Cells; Diphenylhexatriene; Drug Resistance; Kinetics; Leukemia, Experimental; Membrane Fluidity; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate

1981
Analysis of phorbol ester receptors in phorbol ester unresponsive 3T3 cell variants.
    Biochemical and biophysical research communications, 1981, Oct-15, Volume: 102, Issue:3

    Topics: Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cells, Cultured; Genetic Variation; Kinetics; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Drug; Tetradecanoylphorbol Acetate

1981
Cell differentiation, alterations in polyamine levels, and specific binding of phorbol diesters in cultured human cells.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Binding Sites; Carcinogens; Cell Differentiation; Cell Line; Cell Membrane; Humans; Leukemia, Myeloid, Acute; Melanoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Polyamines; Tetradecanoylphorbol Acetate

1982
Modulation of HeLa cell phospholipid metabolism and ornithine decarboxylase activity by tumour promoters: regulation of response to phorbol-12,13-dibutyrate by receptor occupancy time.
    Biochemical and biophysical research communications, 1982, Jun-30, Volume: 106, Issue:4

    Topics: Caenorhabditis elegans Proteins; Carboxy-Lyases; Carrier Proteins; Enzyme Induction; HeLa Cells; Humans; Kinetics; Ornithine Decarboxylase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phospholipids; Protein Kinase C; Receptors, Drug; Tetradecanoylphorbol Acetate

1982
Specific binding of phorbol esters to Friend erythroleukemia cells--general properties, down regulation and relationship to cell differentiation.
    Carcinogenesis, 1982, Volume: 3, Issue:8

    Topics: Animals; Binding Sites; Cell Differentiation; Diterpenes; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Tritium

1982
Specific receptors for phorbol esters in lymphoid cell populations: role in enhanced production of T-cell growth factor.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:2

    Topics: Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Humans; Interleukin-2; Kinetics; Lymphokines; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Drug; Structure-Activity Relationship; T-Lymphocytes; Tetradecanoylphorbol Acetate

1981
Endotoxin-induced tissue factor in human monocytes is dependent upon protein kinase C activation.
    Thrombosis and haemostasis, 1993, Nov-15, Volume: 70, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Endotoxins; Enzyme Activation; Gene Expression Regulation; Humans; Isoquinolines; Monocytes; Naphthalenes; Naphthol AS D Esterase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Polycyclic Compounds; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thromboplastin

1993
Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides.
    Molecular and cellular biology, 1994, Volume: 14, Issue:7

    Topics: Alkaloids; Amino Acid Sequence; Animals; Base Sequence; Benzoquinones; Cell Cycle Proteins; Cell Line; Ceramides; Chlorocebus aethiops; Diglycerides; DNA Primers; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Kinetics; Lactams, Macrocyclic; Molecular Sequence Data; Muromonab-CD3; Mutagenesis, Site-Directed; Naphthalenes; Phorbol 12,13-Dibutyrate; Point Mutation; Polycyclic Compounds; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Proto-Oncogene Proteins p21(ras); Quinones; Receptor Protein-Tyrosine Kinases; Rifabutin; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1994
Possible role of protein kinase C-epsilon isoenzyme in inhibition of interleukin 1 beta induction of nitric oxide synthase in rat renal mesangial cells.
    The Biochemical journal, 1994, Oct-15, Volume: 303 ( Pt 2)

    Topics: Amino Acid Oxidoreductases; Animals; Blotting, Northern; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Induction; Glomerular Mesangium; Interleukin-1; Isoenzymes; NADH Dehydrogenase; Naphthalenes; Nitric Oxide Synthase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Polycyclic Compounds; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate

1994
Loss of adenosine-induced negative inotropic effect in hyperexcited rabbit hearts: relationship to PKC.
    The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 2

    Topics: Acetylcholine; Adenosine; Angiotensin II; Animals; Behavior, Animal; Biphenyl Compounds; Blood Pressure; Depression, Chemical; Enzyme Activation; Heart Rate; Imidazoles; In Vitro Techniques; Losartan; Male; Myocardial Contraction; Naphthalenes; Norepinephrine; Perfusion; Phentolamine; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Propranolol; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Tetrazoles

1995
The protein kinase C isoforms leading to MAP-kinase activation in CHO cells.
    Biochemical and biophysical research communications, 1995, May-25, Volume: 210, Issue:3

    Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; CHO Cells; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Cricetinae; Cytosol; Durapatite; Enzyme Activation; Immunoblotting; Isoenzymes; Kinetics; Molecular Sequence Data; Phorbol 12,13-Dibutyrate; Phosphotyrosine; Protein Kinase C; Tetradecanoylphorbol Acetate; Tyrosine

1995
Phorbol esters elicit Ca(2+)-dependent delayed contractions in diabetic rat aorta.
    European journal of pharmacology, 1995, Jun-06, Volume: 279, Issue:1

    Topics: Alkaloids; Animals; Aorta; Body Weight; Calcium; Diabetes Mellitus, Experimental; Male; Muscle Contraction; Muscle, Smooth, Vascular; Organ Size; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate

1995
Dissociation between changes in cytoplasmic free Ca2+ concentration and insulin secretion as evidenced from measurements in mouse single pancreatic islets.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Oct-10, Volume: 92, Issue:21

    Topics: Animals; Biological Transport; Calcium; Cell Compartmentation; Colforsin; Cytoplasm; Enzyme Inhibitors; Ethers, Cyclic; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Membranes; Mice; Mice, Obese; Okadaic Acid; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Radioimmunoassay; Tetradecanoylphorbol Acetate

1995
Determinants of PKC-dependent modulation of a family of neuronal calcium channels.
    Neuron, 1995, Volume: 15, Issue:4

    Topics: Animals; Calcium; Calcium Channels; Egtazic Acid; Electric Conductivity; Female; GTP-Binding Proteins; Indicators and Reagents; Kinetics; Macromolecular Substances; Neurons; Oocytes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Metabotropic Glutamate; Second Messenger Systems; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Xenopus laevis

1995
Mechanism of interaction of protein kinase C with phorbol esters. Reversibility and nature of membrane association.
    The Journal of biological chemistry, 1995, Oct-27, Volume: 270, Issue:43

    Topics: Calcium; Diglycerides; Kinetics; Liposomes; Membrane Fluidity; Osmolar Concentration; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylcholines; Protein Binding; Protein Kinase C; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Tryptophan

1995
Depression of the spontaneous activity by phorbol esters in young embryonic chick cardiomyocytes.
    Japanese journal of pharmacology, 1995, Volume: 67, Issue:4

    Topics: Action Potentials; Animals; Calcium Channels; Cardiac Pacing, Artificial; Chick Embryo; Computer Simulation; Heart Conduction System; Heart Ventricles; Myocardium; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C; Temperature; Tetradecanoylphorbol Acetate

1995
Influence of protein kinase C activation on basophils from patients with atopic dermatitis in comparison with nonatopic controls.
    Dermatology (Basel, Switzerland), 1993, Volume: 186, Issue:2

    Topics: Adolescent; Adult; Aged; Basophils; Bombesin; Dermatitis, Atopic; Diglycerides; Diterpenes; Eczema; Enzyme Activation; Female; Histamine; Histamine Release; Humans; Immunoglobulin E; Male; Middle Aged; Phorbol 12,13-Dibutyrate; Protein Kinase C; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate

1993
Differential effects of putative protein kinase C inhibitors on contraction of rat aortic smooth muscle.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Aorta; Dose-Response Relationship, Drug; Isoquinolines; Male; Muscle, Smooth, Vascular; Naphthalenes; Phenylephrine; Phorbol 12,13-Dibutyrate; Piperazines; Polycyclic Compounds; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Vasoconstriction

1993
Calcium dependent positive inotropic effects of low phorbol ester concentrations in isolated rat hearts.
    Cardiovascular research, 1993, Volume: 27, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Chloride; Dose-Response Relationship, Drug; Drug Interactions; Energy Metabolism; Male; Myocardial Contraction; Myocardium; Phorbol 12,13-Dibutyrate; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Time Factors

1993
Regulation of parathyroid hormone messenger RNA levels by protein kinase A and C in bovine parathyroid cells.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1995, Volume: 10, Issue:3

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Alkaloids; Analysis of Variance; Animals; Calcium; Cattle; Cells, Cultured; Cholera Toxin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Gene Expression Regulation, Enzymologic; Nucleic Acid Hybridization; Parathyroid Glands; Parathyroid Hormone; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Protein Kinase C; RNA, Messenger; RNA, Ribosomal, 18S; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1995
Up- and down-modulation of a cloned Aplysia K+ channel (AKv1.1a) by the activators of protein kinase C.
    Zoological science, 1995, Volume: 12, Issue:1

    Topics: Amino Acid Sequence; Animals; Aplysia; Base Sequence; Cloning, Molecular; Diglycerides; DNA, Complementary; Down-Regulation; Enzyme Activation; Kinetics; Molecular Sequence Data; Phorbol 12,13-Dibutyrate; Phosphorylation; Potassium Channels; Protein Kinase C; Shaker Superfamily of Potassium Channels; Tetradecanoylphorbol Acetate; Up-Regulation; Xenopus

1995
Multiple intracellular signallings are involved in thyrotropin-releasing hormone (TRH)-induced c-fos and jun B mRNA levels in clonal prolactin cells.
    Molecular and cellular endocrinology, 1995, Volume: 107, Issue:1

    Topics: Adenylyl Cyclases; Animals; Calcium; Clone Cells; Colforsin; Cyclic AMP; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Ionomycin; Neoplasm Proteins; Nuclear Proteins; Phorbol 12,13-Dibutyrate; Pituitary Gland, Anterior; Pituitary Neoplasms; Prolactin; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured

1995
Activation of protein kinase C by phorbol esters disrupts the tegument of Schistosoma mansoni.
    Parasitology, 1994, Volume: 109 ( Pt 4)

    Topics: Animals; Biomphalaria; Enzyme Activation; Female; Humans; Male; Mice; Microscopy, Electron; Microscopy, Electron, Scanning; Phorbol 12,13-Dibutyrate; Protein Kinase C; Schistosoma mansoni; Tetradecanoylphorbol Acetate

1994
Mutual antagonistic interactions between the thyrotropin (adenosine 3',5'-monophosphate) and protein kinase C/epidermal growth factor (tyrosine kinase) pathways in cell proliferation and differentiation of cultured human thyroid follicles.
    Endocrinology, 1995, Volume: 136, Issue:2

    Topics: Alkaloids; Cell Differentiation; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Epidermal Growth Factor; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein-Tyrosine Kinases; Second Messenger Systems; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin

1995
Differentiation- and protein kinase C-dependent regulation of alanine transport via system B.
    The Journal of biological chemistry, 1995, Feb-24, Volume: 270, Issue:8

    Topics: Alanine; beta-Alanine; Biological Transport; Cell Differentiation; Cell Line; Cellular Senescence; Humans; Kinetics; Phorbol 12,13-Dibutyrate; Protein Kinase C; Sodium; Tetradecanoylphorbol Acetate

1995
Mechanism of transferrin receptor down-regulation in K562 cells in response to protein kinase C activation.
    The Journal of biological chemistry, 1995, Feb-24, Volume: 270, Issue:8

    Topics: Bryostatins; Cell Compartmentation; Down-Regulation; Endocytosis; Enzyme Activation; Humans; Lactones; Macrolides; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Induction of c-fos in pituitary cells by thyrotrophin-releasing hormone and phorbol 12-myristate 13-acetate depends upon Ca2+ influx.
    Journal of molecular endocrinology, 1994, Volume: 13, Issue:3

    Topics: Alkaloids; Animals; Calcium; Cell Line; Culture Media, Serum-Free; Cytoplasm; Down-Regulation; Edetic Acid; Egtazic Acid; Epidermal Growth Factor; Gene Expression Regulation; Genes, fos; Phorbol 12,13-Dibutyrate; Pituitary Gland; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Transcription, Genetic

1994
Heterologous sensitization of adenylate cyclase activity by serotonin in the rat cerebral cortex.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1993, Volume: 3, Issue:4

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Cerebral Cortex; Colforsin; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Phorbol 12,13-Dibutyrate; Propanolamines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Somatostatin; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide

1993
Phorbol esters impair endothelium-dependent and independent relaxation in rat aortic rings.
    General pharmacology, 1994, Volume: 25, Issue:3

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcimycin; Endothelium, Vascular; Enzyme Activation; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

1994
Translocation of protein kinase Cs in Aplysia neurons: evidence for complex regulation.
    Brain research. Molecular brain research, 1994, Volume: 24, Issue:1-4

    Topics: Animals; Aplysia; Ganglia, Invertebrate; Immunoblotting; In Vitro Techniques; Isoenzymes; Kinetics; Neurons; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Processing, Post-Translational; Synaptosomes; Tetradecanoylphorbol Acetate

1994
Phorbol ester-, but not ligand-mediated activation of protein kinase C increases angiotensin binding to rat intestinal epithelial (RIE-1) cells.
    Biochemistry and molecular biology international, 1994, Volume: 33, Issue:5

    Topics: Angiotensin II; Animals; Cell Line; Enzyme Activation; Epithelial Cells; Intestinal Mucosa; Ionomycin; Ligands; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Receptors, Angiotensin; Tetradecanoylphorbol Acetate; Up-Regulation

1994
Tobacco smoke tumor promoters, catechol and hydroquinone, induce oxidative regulation of protein kinase C and influence invasion and metastasis of lung carcinoma cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Dec-06, Volume: 91, Issue:25

    Topics: Animals; Carcinogens; Catechols; Cell Membrane; Chelating Agents; Cytosol; Hydroquinones; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred Lew; Smoke; Smoking; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Elevation of intracellular Ca2+ concentration by protein kinase C stimulation in isolated single rabbit sino-atrial node cells.
    General pharmacology, 1994, Volume: 25, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Electrophysiology; Fura-2; In Vitro Techniques; Isoproterenol; Isoquinolines; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rabbits; Sinoatrial Node; Stimulation, Chemical; Tetradecanoylphorbol Acetate

1994
Protein kinase C and adaptation to ethanol.
    EXS, 1994, Volume: 71

    Topics: Acclimatization; Animals; Calcium; Calcium Channels; Cell Differentiation; Ethanol; Isoenzymes; Nerve Growth Factors; Neurites; Neurons; PC12 Cells; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; RNA, Messenger; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate

1994
Overexpressed protein kinase C-delta and -epsilon subtypes in NIH 3T3 cells exhibit differential subcellular localization and differential regulation of sodium-dependent phosphate uptake.
    The Journal of biological chemistry, 1994, Feb-18, Volume: 269, Issue:7

    Topics: 3T3 Cells; Animals; Biological Transport; Blotting, Western; Cell Division; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Gene Expression; Isoenzymes; Kinetics; Mice; Phorbol 12,13-Dibutyrate; Phosphates; Protein Binding; Protein Kinase C; Sodium; Subcellular Fractions; Tetradecanoylphorbol Acetate; Transfection; Zinc

1994
Involvement of protein kinase C activation in regulation of acetylcholine release from rat hippocampal slices by minaprine.
    Neurochemistry international, 1994, Volume: 24, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Acetylcholine; Alkaloids; Animals; Enzyme Activation; Hippocampus; In Vitro Techniques; Isoquinolines; Male; Phorbol 12,13-Dibutyrate; Piperazines; Potassium; Protein Kinase C; Pyridazines; Rats; Rats, Wistar; Serotonin; Staurosporine; Synaptosomes; Tetradecanoylphorbol Acetate

1994
Schistosoma mansoni: myogenic characteristics of phorbol ester-induced muscle contraction.
    Experimental parasitology, 1994, Volume: 78, Issue:3

    Topics: Acetylcholine; Animals; Cadmium; Calcimycin; Calcium; Calcium Channels; Carbachol; Cell Membrane Permeability; Dose-Response Relationship, Drug; Electromyography; Hydrogen-Ion Concentration; Male; Membrane Potentials; Microelectrodes; Muscle Contraction; Nicardipine; Phorbol 12,13-Dibutyrate; Praziquantel; Protein Kinase C; Schistosoma mansoni; Serotonin; Sodium; Tetradecanoylphorbol Acetate

1994
Interplay between differentiation and cell cycle arrest at G1 in phorbol diester-treated human myelocytic leukemia cells.
    International journal of hematology, 1993, Volume: 58, Issue:1-2

    Topics: Cell Differentiation; G1 Phase; Humans; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Growth of melanocytic cells is associated with down-regulation of protein kinase C alpha, delta, and epsilon isoforms. Possible role of diacylglycerol.
    The Journal of biological chemistry, 1993, Nov-15, Volume: 268, Issue:32

    Topics: Animals; Cell Division; Cells, Cultured; Diglycerides; DNA; Down-Regulation; Isoenzymes; Melanocytes; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate

1993
1,25-Dihydroxyvitamin D3 and macrophage colony-stimulating factor-1 synergistically phosphorylate talin.
    Journal of cellular biochemistry, 1993, Volume: 53, Issue:2

    Topics: Alkaloids; Animals; Calcitriol; Cell Line; Drug Synergism; Genistein; Isoflavones; L Cells; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Kinase C; Protein-Tyrosine Kinases; Receptor, Macrophage Colony-Stimulating Factor; Staurosporine; Talin; Tetradecanoylphorbol Acetate

1993
Phorbol ester sequentially downregulates cAMP-regulated basolateral and apical Cl- transport pathways in T84 cells.
    The American journal of physiology, 1993, Volume: 265, Issue:4 Pt 1

    Topics: Biological Transport; Carrier Proteins; Cell Line; Cell Membrane; Chlorides; Colforsin; Colon; Cyclic AMP; Electrophysiology; Humans; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Time Factors

1993
Effects of tannic acid on 12-O-tetradecanoylphorbol-13-acetate-induced protein kinase C activation in NIH 3T3 cells.
    Biochemical pharmacology, 1993, Oct-19, Volume: 46, Issue:8

    Topics: 3T3 Cells; Animals; DNA; Drug Interactions; Enzyme Activation; Hydrolyzable Tannins; Mice; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate

1993
Phorbol 12-myristate 13-acetate stimulates proliferation and ductal morphogenesis and inhibits functional differentiation of normal rat mammary epithelial cells in primary culture.
    Journal of cellular physiology, 1994, Volume: 158, Issue:1

    Topics: Animals; Caseins; Cell Differentiation; Cell Division; Cells, Cultured; Epithelial Cells; Epithelium; Female; Mammary Glands, Animal; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Reference Values; Tetradecanoylphorbol Acetate

1994
Effects of phorbol esters on contraction and protein kinase C activation in rabbit aorta.
    Life sciences, 1994, Volume: 54, Issue:2

    Topics: Animals; Aorta, Thoracic; Enzyme Activation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate

1994
Diradylglycerols stimulate phospholipase A2 and subsequent exocytosis in ram spermatozoa. Evidence that the effect is not mediated via protein kinase C.
    The Biochemical journal, 1994, Jan-01, Volume: 297 ( Pt 1)

    Topics: Acrosome; Animals; Arachidonic Acid; Calcimycin; Calcium; Diglycerides; Enzyme Activation; Exocytosis; Glycerides; Male; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Protein Kinase C; Sheep; Spermatozoa; Tetradecanoylphorbol Acetate

1994
Toxicity of phorbol esters for human epithelial cells expressing a mutant ras oncogene.
    Molecular carcinogenesis, 1993, Volume: 8, Issue:4

    Topics: Antineoplastic Agents; Bryostatins; Cell Division; Cell Line; DNA; Epithelial Cells; Epithelium; Gene Expression Regulation; Genes, ras; Humans; Lactones; Macrolides; Models, Biological; Mutation; Phorbol 12,13-Dibutyrate; Phorbol Esters; Proto-Oncogene Proteins p21(ras); Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thyroid Gland; Zinc

1993
Phorbol esters and norepinephrine destabilize alpha 1B-adrenergic receptor mRNA in vascular smooth muscle cells.
    The Journal of biological chemistry, 1994, Jan-21, Volume: 269, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta; Bradykinin; Cells, Cultured; Diglycerides; Down-Regulation; Ethers, Cyclic; Inositol Phosphates; Isoquinolines; Kinetics; Models, Biological; Muscle, Smooth, Vascular; Norepinephrine; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Rabbits; Receptors, Adrenergic, alpha-1; RNA, Messenger; Tetradecanoylphorbol Acetate

1994
Protein kinase C-mediated inhibition of vascular smooth muscle cell proliferation: the isoforms that may mediate G1/S inhibition.
    Experimental cell research, 1993, Volume: 208, Issue:1

    Topics: Animals; Cell Cycle; Cells, Cultured; In Vitro Techniques; Isoenzymes; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Protein Kinase C; S Phase; Swine; Tetradecanoylphorbol Acetate

1993
Protein kinase C modulates glutamate receptor inhibition of Ca2+ channels and synaptic transmission.
    Nature, 1993, Jan-14, Volume: 361, Issue:6408

    Topics: Animals; Calcium Channels; Cyclopentanes; Dimethyl Sulfoxide; Enzyme Activation; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kinetics; Membrane Potentials; Neurons; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyramidal Tracts; Rats; Receptors, Glutamate; Synapses; Synaptic Transmission; Tetradecanoylphorbol Acetate

1993
Phorbol esters inhibit insulin-induced receptor down-regulation in cultured human lymphocytes: association with diminished insulin receptor autophosphorylation.
    The Biochemical journal, 1993, Feb-15, Volume: 290 ( Pt 1)

    Topics: Cell Line; Down-Regulation; Enzyme Activation; Humans; Insulin; Lymphocytes; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptor, Insulin; Sphingosine; Tetradecanoylphorbol Acetate

1993
Type-specific stimulation of adenylylcyclase by protein kinase C.
    The Journal of biological chemistry, 1993, Mar-05, Volume: 268, Issue:7

    Topics: Adenylyl Cyclases; Alkaloids; Cells, Cultured; Cyclic AMP; DNA; Enzyme Activation; Humans; Isoenzymes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Transfection

1993
alpha-Adrenergic augmentation of myogenic response in rat arterioles: role of protein kinase C.
    The American journal of physiology, 1993, Volume: 264, Issue:2 Pt 2

    Topics: Animals; Arterioles; In Vitro Techniques; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Vasoconstriction

1993
Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Diazoxide; Diterpenes; Glucose; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Mice; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Potassium; Potassium Channels; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate

1993
Phorbol ester-stimulated exocytosis in lacrimal gland: PKC might not be the sole effector.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: Alkaloids; Animals; Benzophenanthridines; Bucladesine; Diglycerides; Exocytosis; In Vitro Techniques; Lacrimal Apparatus; Male; Phenanthridines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Trifluoperazine

1993
Genistein induces apoptosis in immature human thymocytes by inhibiting topoisomerase-II.
    Biochemical and biophysical research communications, 1993, Jul-30, Volume: 194, Issue:2

    Topics: Apoptosis; Benzoquinones; Cells, Cultured; Chromatin; DNA Damage; Etoposide; Genistein; Humans; Immunophenotyping; Infant; Isoflavones; Kinetics; Lactams, Macrocyclic; Methylprednisolone; Novobiocin; Phorbol 12,13-Dibutyrate; Protein-Tyrosine Kinases; Quinones; Rifabutin; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland; Time Factors; Topoisomerase II Inhibitors

1993
Modulation of beta-amyloid precursor protein secretion in differentiated and nondifferentiated cells.
    Biochemical and biophysical research communications, 1993, Aug-31, Volume: 195, Issue:1

    Topics: Amyloid beta-Protein Precursor; Animals; Bucladesine; Calcimycin; Carcinogens; Cell Differentiation; Cell Line; Culture Media; PC12 Cells; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate

1993
Effect of protein kinase-C depletion on inositol trisphosphate-mediated and cyclic adenosine 3',5'-monophosphate-dependent protein kinase-mediated adrenocorticotropin secretion.
    Endocrinology, 1993, Volume: 133, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Cyclic AMP; Cycloheximide; Diglycerides; Inositol 1,4,5-Trisphosphate; Ionomycin; Male; Perfusion; Phorbol 12,13-Dibutyrate; Pituitary Gland, Anterior; Potassium Chloride; Protein Kinase C; Protein Kinases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

1993
Further characterization of 5-HT- and 5-HT3 receptor agonists'-stimulated phosphoinositol phosphates accumulation.
    Brain research, 1993, Jul-16, Volume: 617, Issue:1

    Topics: Animals; GTP-Binding Proteins; Inositol Phosphates; Male; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbols; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1993
Possible involvement of protein kinase C in gonadotropin-induced ovulation in the rat ovary.
    Endocrinology, 1993, Volume: 133, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bucladesine; Cells, Cultured; Female; Gonadotropins, Equine; Granulosa Cells; Isoquinolines; Luteinizing Hormone; Ovary; Ovulation; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator

1993
Phorbol myristate acetate induction of chemotactic migration of human polymorphonuclear neutrophils.
    Inflammation, 1993, Volume: 17, Issue:4

    Topics: Chemotaxis, Leukocyte; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol 12,13-Dibutyrate; Tetradecanoylphorbol Acetate

1993
Evidence for an altered protein kinase C (PKC) signaling pathway in psoriasis.
    The Journal of investigative dermatology, 1993, Volume: 101, Issue:4

    Topics: Alkaloids; Cells, Cultured; Fluorometry; Humans; Isoelectric Focusing; Keratinocytes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Psoriasis; Reference Values; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate

1993
Role for protein kinase C in the mediation of increased fibronectin accumulation by mesangial cells grown in high-glucose medium.
    Diabetes, 1993, Volume: 42, Issue:1

    Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Female; Fibronectins; Glomerular Mesangium; Glucose; Intracellular Signaling Peptides and Proteins; Kinetics; Membrane Proteins; Molecular Weight; Myristoylated Alanine-Rich C Kinase Substrate; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

1993
Two phorbol ester receptor affinities in partially transformed human urothelial cells and decrease of receptor binding in desensitized cells.
    Experientia, 1993, Jan-15, Volume: 49, Issue:1

    Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line, Transformed; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Drug; Tetradecanoylphorbol Acetate; Urinary Bladder; Urinary Bladder Neoplasms

1993
Stimulation of calcium uptake in Saccharomyces cerevisiae by bovine protein kinase C alpha.
    The Journal of biological chemistry, 1993, Feb-15, Volume: 268, Issue:5

    Topics: Amino Acid Sequence; Animals; Base Sequence; Calcium; Cattle; Kinetics; Molecular Sequence Data; Oligodeoxyribonucleotides; Oligopeptides; Phorbol 12,13-Dibutyrate; Plasmids; Protein Binding; Protein Kinase C; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity; Tetradecanoylphorbol Acetate

1993
Role of protein kinase C in bradykinin-induced prostaglandin formation in osteoblasts.
    European journal of pharmacology, 1993, Jan-15, Volume: 244, Issue:2

    Topics: Alkaloids; Animals; Bradykinin; Calcimycin; Cell Membrane; Cells, Cultured; Dinoprostone; Enzyme Activation; Hydrocortisone; Indomethacin; Mice; Osteoblasts; Phorbol 12,13-Dibutyrate; Prostaglandins; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate

1993
Cobra venom cardiotoxin (cytotoxin) isoforms and neurotoxin: comparative potency of protein kinase C inhibition and cancer cell cytotoxicity and modes of enzyme inhibition.
    Biochemistry, 1993, Mar-02, Volume: 32, Issue:8

    Topics: Amino Acid Sequence; Animals; Brain; Cell Differentiation; Cell Survival; Cytotoxins; Elapid Venoms; Humans; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Neurotoxins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Sequence Homology, Amino Acid; Structure-Activity Relationship; Swine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Characterization of [3H]staurosporine binding in protein kinase C-II purified from rat brain.
    Neurochemistry international, 1993, Volume: 22, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenine Nucleotides; Alkaloids; Animals; Brain; Calcium; Carbazoles; Guanine Nucleotides; Indole Alkaloids; Isoquinolines; Phorbol 12,13-Dibutyrate; Phosphatidylserines; Piperazines; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate; Zinc

1993
Ethanol and protein kinase C in rat brain.
    Neurochemistry international, 1993, Volume: 22, Issue:6

    Topics: Animals; Autoradiography; Brain; Ethanol; Hippocampus; Male; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Phosphatidylserines; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Synaptosomes; Tetradecanoylphorbol Acetate

1993
Inhibition of protein kinase C suppresses megakaryocytic differentiation and stimulates erythroid differentiation in HEL cells.
    Blood, 1996, Jan-01, Volume: 87, Issue:1

    Topics: Aphidicolin; Biomarkers; Blood Proteins; Cell Cycle; Cell Differentiation; Enzyme Inhibitors; Erythroid Precursor Cells; Gene Expression Regulation, Leukemic; Globins; Glycophorins; Hematopoietic Stem Cells; Hemin; Humans; Indoles; Leukemia, Erythroblastic, Acute; Maleimides; Megakaryocytes; Neoplasm Proteins; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
LY290181, an inhibitor of diabetes-induced vascular dysfunction, blocks protein kinase C-stimulated transcriptional activation through inhibition of transcription factor binding to a phorbol response element.
    Diabetes, 1996, Volume: 45, Issue:5

    Topics: Animals; Base Sequence; Capillaries; Cattle; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelium, Vascular; Enzyme Inhibitors; Fibroblasts; Humans; Male; Molecular Sequence Data; Naphthalenes; Oligodeoxyribonucleotides; Phorbol 12,13-Dibutyrate; Promoter Regions, Genetic; Protein Kinase C; Pyrans; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Retinal Vessels; Skin; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Urokinase-Type Plasminogen Activator

1996
The role of protein kinase C in carbachol-induced and of cAMP-dependent protein kinase in isoproterenol-induced secretion in primary cultured guinea pig parotid acinar cells.
    The Biochemical journal, 1996, Feb-15, Volume: 314 ( Pt 1)

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Amylases; Animals; Calcium; Carbachol; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Exocytosis; Guinea Pigs; Immunoblotting; Isoproterenol; Isoquinolines; Male; Parotid Gland; Phorbol 12,13-Dibutyrate; Piperazines; Protein Binding; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate

1996
Tamoxifen modulates protein kinase C via oxidative stress in estrogen receptor-negative breast cancer cells.
    The Journal of biological chemistry, 1996, Jun-07, Volume: 271, Issue:23

    Topics: Animals; Antioxidants; Breast Neoplasms; Cattle; Cell Division; Cell Membrane; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; In Vitro Techniques; Oxidative Stress; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rabbits; Receptors, Estrogen; Second Messenger Systems; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vitamin E

1996
Mechanism of bile salt-induced mucin secretion by cultured dog gallbladder epithelial cells.
    The Biochemical journal, 1996, Jun-15, Volume: 316 ( Pt 3)

    Topics: Acetylglucosamine; Animals; Bile Acids and Salts; Calcimycin; Cells, Cultured; Cyclic AMP; Dinoprostone; Dogs; Edetic Acid; Enzyme Activation; Epithelium; Gallbladder; Ionomycin; Kinetics; Mucins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Second Messenger Systems; Taurochenodeoxycholic Acid; Taurocholic Acid; Tetradecanoylphorbol Acetate; Tritium

1996
The role of the 90-kDa heat shock protein in cell cycle control and differentiation of the monoblastoid cell line U937.
    Experimental cell research, 1996, Aug-01, Volume: 226, Issue:2

    Topics: Antigens, CD; Cell Adhesion; Cell Adhesion Molecules; Cell Cycle; Cell Differentiation; Cell Division; Cell Line; DNA, Antisense; Gene Expression; Heat-Shock Proteins; Heat-Shock Response; HSP90 Heat-Shock Proteins; Humans; Mitogens; Monocytes; Phorbol 12,13-Dibutyrate; Tetradecanoylphorbol Acetate; Transfection

1996
Separate upstream and convergent downstream pathways of G-protein- and phorbol ester-mediated Ca2+ sensitization of myosin light chain phosphorylation in smooth muscle.
    The Biochemical journal, 1996, Sep-01, Volume: 318 ( Pt 2)

    Topics: Animals; Calcium; Carbachol; Cell Membrane; Cytosol; Femoral Artery; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ileum; In Vitro Techniques; Isoenzymes; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Myosin Light Chains; Phorbol 12,13-Dibutyrate; Phosphorylation; Portal Vein; Protein Kinase C; Rabbits; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Type C Phospholipases

1996
Phorbol esters but not the cholinergic agonists oxotremorine-M and carbachol increase release of the amyloid precursor protein in cultured rat cortical neurons.
    Journal of neurochemistry, 1996, Volume: 67, Issue:4

    Topics: Amyloid beta-Protein Precursor; Animals; Atropine; Carbachol; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Muscarinic Agonists; Neurons; Oxotremorine; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate

1996
The structural requirements for phorbol esters to enhance noradrenaline and dopamine release from rat brain cortex.
    British journal of pharmacology, 1996, Volume: 119, Issue:1

    Topics: Animals; Cerebral Cortex; Dopamine; In Vitro Techniques; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tritium

1996
Calcitonin-induced changes in the cytoskeleton are mediated by a signal pathway associated with protein kinase A in osteoclasts.
    Endocrinology, 1996, Volume: 137, Issue:11

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Animals, Newborn; Bucladesine; Calcitonin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Dentin; Enzyme Activation; Hematopoietic Stem Cells; Male; Mice; Mice, Inbred Strains; Osteoblasts; Phorbol 12,13-Dibutyrate; Protein Kinase C; Signal Transduction; Skull; Tetradecanoylphorbol Acetate; Thionucleotides

1996
Phorbol-12,13-dibutyrate and pinacidil cardioplegia. Novel forms of myoprotection.
    Circulation, 1996, Nov-01, Volume: 94, Issue:9 Suppl

    Topics: Animals; Diastole; Female; Guanidines; Heart; Heart Arrest, Induced; Hemodynamics; Male; Myocardial Contraction; Phorbol 12,13-Dibutyrate; Pinacidil; Potassium Channels; Protein Kinase C; Sheep; Tetradecanoylphorbol Acetate

1996
Protein kinase C activation and phosphate uptake are altered in intact mucolipidosis type-4 skin fibroblasts.
    Biochemical and molecular medicine, 1996, Volume: 59, Issue:1

    Topics: Blotting, Western; Fibroblasts; Humans; Mucolipidoses; Phorbol 12,13-Dibutyrate; Phosphates; Protein Kinase C; Skin; Tetradecanoylphorbol Acetate

1996
Involvement of mitogen-activated protein kinase and translocation of cytosolic phospholipase A2 to the nuclear envelope in acetylcholine-induced prostacyclin synthesis in rabbit coronary endothelial cells.
    Molecular pharmacology, 1996, Volume: 50, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Amino Acid Sequence; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Cells, Cultured; Coronary Vessels; Cytosol; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Molecular Sequence Data; Naphthalenes; Nitriles; Nitrophenols; Nuclear Envelope; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Phosphorylation; Rabbits; Tetradecanoylphorbol Acetate; Tyrphostins

1996
Protein kinase C modulates flow-initiated contraction.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rabbits; Regional Blood Flow; Staurosporine; Tetradecanoylphorbol Acetate; Vasoconstriction

1996
Activation of protein kinase C-alpha and translocation of the myristoylated alanine-rich C-kinase substrate correlate with phorbol ester-enhanced noradrenaline release from SH-SY5Y human neuroblastoma cells.
    Journal of neurochemistry, 1997, Volume: 68, Issue:1

    Topics: Alanine; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Neuroblastoma; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Phosphotransferases; Protein Kinase C; Proteins; Subcellular Fractions; Substrate Specificity; Tetradecanoylphorbol Acetate; Tissue Distribution; Translocation, Genetic; Tumor Cells, Cultured

1997
The catalytic domain of protein kinase C-delta in reciprocal delta and epsilon chimeras mediates phorbol ester-induced macrophage differentiation of mouse promyelocytes.
    The Journal of biological chemistry, 1997, Jan-03, Volume: 272, Issue:1

    Topics: Animals; Antigens, Differentiation; Cell Adhesion; Cell Differentiation; Cell Line; Hematopoiesis; Isoenzymes; Macrophage Activation; Macrophage-1 Antigen; Macrophages; Mice; Phagocytosis; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate

1997
Metabotropic glutamate receptor activation modulates kainate and serotonin calcium response in astrocytes.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Mar-01, Volume: 17, Issue:5

    Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Astrocytes; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cerebral Cortex; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Nimodipine; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Protein Kinase C; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Second Messenger Systems; Serotonin; Suprachiasmatic Nucleus; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1997
Antiproliferative effect of Pygeum africanum extract on rat prostatic fibroblasts.
    The Journal of urology, 1997, Volume: 157, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogens; Cell Division; DNA; Dose-Response Relationship, Drug; Epidermal Growth Factor; Fatty Alcohols; Fibroblast Growth Factor 10; Fibroblast Growth Factor 2; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Fibroblasts; Growth Substances; Insulin-Like Growth Factor I; Male; Phorbol 12,13-Dibutyrate; Plant Extracts; Prostate; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

1997
Blockade of protein kinase C is involved in the inhibition by cycloheterophyllin of neutrophil superoxide anion generation.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:5

    Topics: Animals; Arachidonic Acid; Carcinogens; Cyclic AMP-Dependent Protein Kinases; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Inositol 1,4,5-Trisphosphate; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate

1997
Turning of nerve growth cones induced by the activation of protein kinase C.
    Neuroreport, 1997, May-27, Volume: 8, Issue:8

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Calcium Channels; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Isoenzymes; Neurons; Phorbol 12,13-Dibutyrate; Protein Kinase C; Purinergic Antagonists; Spinal Cord; Tetradecanoylphorbol Acetate; Xenopus

1997
Bryostatin 1 induces biphasic activation of protein kinase D in intact cells.
    The Journal of biological chemistry, 1997, Aug-08, Volume: 272, Issue:32

    Topics: 3T3 Cells; Animals; Bryostatins; Dose-Response Relationship, Drug; Enzyme Activation; Kinetics; Lactones; Macrolides; Mice; Mitogens; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate

1997
Effects of phorbol ester on carbachol-induced contraction in bovine ciliary muscle: possible involvement of protein kinase C.
    European journal of pharmacology, 1997, Jul-09, Volume: 330, Issue:2-3

    Topics: Animals; Carbachol; Cattle; Ciliary Body; Drug Interactions; Histones; In Vitro Techniques; Muscarinic Agonists; Muscle Contraction; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Receptors, Muscarinic; Stimulation, Chemical; Tetradecanoylphorbol Acetate

1997
Inhibition by protein kinase C of the 86Rb+ efflux and vasorelaxation induced by P1075, a K(ATP) channel opener, in rat isolated aorta.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:3

    Topics: Adenosine Triphosphate; Animals; Aorta; Enzyme Activation; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Binding; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes; Tetradecanoylphorbol Acetate

1997
Potentiation of ara-C-induced apoptosis by the protein kinase C activator bryostatin 1 in human leukemia cells (HL-60) involves a process dependent upon c-Myc.
    Biochemical pharmacology, 1997, Sep-01, Volume: 54, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Bryostatins; Cell Cycle; Cytarabine; Diterpenes; DNA Fragmentation; Drug Synergism; Enzyme Activation; HL-60 Cells; Humans; Kinetics; Lactones; Macrolides; Oligonucleotides, Antisense; Phorbol 12,13-Dibutyrate; Protein Kinase C; Proto-Oncogene Proteins c-myc; Terpenes; Tetradecanoylphorbol Acetate; Thionucleotides

1997
Evidence for the involvement of protein kinase C inhibition by norathyriol in the reduction of phorbol ester-induced neutrophil superoxide anion generation and aggregation.
    European journal of pharmacology, 1997, Oct-01, Volume: 336, Issue:1

    Topics: Animals; Cell Aggregation; Cyclic AMP-Dependent Protein Kinases; Neutrophils; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Trypsin; Xanthenes

1997
Selenocompounds induce a redox modulation of protein kinase C in the cell, compartmentally independent from cytosolic glutathione: its role in inhibition of tumor promotion.
    Archives of biochemistry and biophysics, 1997, Dec-01, Volume: 348, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromatography, DEAE-Cellulose; Cystine; Cytosol; Glutathione; Glutathione Disulfide; Isoenzymes; Kinetics; Mice; Organoselenium Compounds; Oxidation-Reduction; Phorbol 12,13-Dibutyrate; Protein Kinase C; Sodium Selenite; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1997
Acetylcholine agonists stimulate mitogen-activated protein kinase in oligodendrocyte progenitors by muscarinic receptors.
    Journal of neuroscience research, 1997, Dec-01, Volume: 50, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Atropine; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cells, Cultured; Cholinergic Agents; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Indoles; Maleimides; Mitogen-Activated Protein Kinase 1; Oligodendroglia; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction; Stem Cells; Tetradecanoylphorbol Acetate

1997
Protein kinase C inhibition enhances platelet-activating factor-induced eicosanoid production in human eosinophils.
    American journal of respiratory cell and molecular biology, 1998, Volume: 18, Issue:1

    Topics: Arachidonic Acid; Calcium; Catalase; Eicosanoids; Enzyme Inhibitors; Eosinophils; Female; Humans; Indoles; Leukotriene C4; Male; Maleimides; Naphthalenes; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2

1998
Regulation of aquaporin-4 water channels by phorbol ester-dependent protein phosphorylation.
    The Journal of biological chemistry, 1998, Mar-13, Volume: 273, Issue:11

    Topics: Animals; Aquaporin 4; Aquaporins; Biological Transport; Enzyme Activation; Ion Channels; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Protein Kinase C; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Water

1998
Inhibition of cromolyn-induced phosphorylation of a 78-kDa protein by phorbol esters in rat peritoneal mast cells.
    Biochemical pharmacology, 1998, Mar-01, Volume: 55, Issue:5

    Topics: Animals; Cells, Cultured; Cromolyn Sodium; Histamine Release; Immunoglobulin E; Male; Mast Cells; Peritoneal Cavity; Phorbol 12,13-Dibutyrate; Phosphorylation; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

1998
Dietary lipid varying in corn and coconut oil influences protein kinase C in phorbol ester-treated mouse skin.
    Nutrition and cancer, 1998, Volume: 30, Issue:2

    Topics: Animals; Biological Transport; Cell Membrane; Coconut Oil; Corn Oil; Dietary Fats; Female; Isoenzymes; Mice; Phorbol 12,13-Dibutyrate; Plant Oils; Protein Kinase C; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1998
Different effects of phorbol ester derivates on human immunodeficiency virus 1 replication in lymphocytic and monocytic human cells.
    Acta virologica, 1997, Volume: 41, Issue:5

    Topics: HIV-1; Humans; Jurkat Cells; Lymphocytes; Monocytes; Phorbol 12,13-Dibutyrate; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virus Replication

1997
Endogenous activation of apoptosis in bursal lymphocytes: inhibition by phorbol esters and protein synthesis inhibitors.
    Cellular immunology, 1998, Mar-15, Volume: 184, Issue:2

    Topics: Animals; Apoptosis; B-Lymphocytes; Bursa of Fabricius; Cell Differentiation; Cells, Cultured; Chickens; DNA Fragmentation; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Protein Synthesis Inhibitors; Signal Transduction; Tetradecanoylphorbol Acetate

1998
Taurine might be acting as a trophic factor in the retina by modulating phosphorylation of cellular proteins.
    Journal of neuroscience research, 1998, Aug-01, Volume: 53, Issue:3

    Topics: Animals; Antineoplastic Agents, Hormonal; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Eye Proteins; Goldfish; Growth Substances; Indoles; Lactams; Marine Toxins; Okadaic Acid; Optic Nerve; Oxazoles; Phorbol 12,13-Dibutyrate; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Retina; Sulfonamides; Tamoxifen; Taurine; Tetradecanoylphorbol Acetate

1998
Assessment of the mechanism by which prolactin stimulates progesterone production by early corpora lutea of pigs.
    The Journal of endocrinology, 1998, Volume: 159, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carcinogens; Cells, Cultured; Corpus Luteum; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Female; Ionomycin; Ionophores; Lipoproteins, LDL; Luteal Phase; Phorbol 12,13-Dibutyrate; Progesterone; Prolactin; Protein Kinase C; Staurosporine; Stimulation, Chemical; Swine; Tetradecanoylphorbol Acetate; Type C Phospholipases

1998
Mucin secretion by the human colon cell line LS174T is regulated by bile salts.
    Glycobiology, 1999, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Animals; Bile Acids and Salts; Colon; Colonic Neoplasms; Dogs; Enzyme Activation; Epithelium; Humans; Mucins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Solutions; Structure-Activity Relationship; Taurochenodeoxycholic Acid; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured

1999
Thrombopoietin potentiates the protein-kinase-C-mediated activation of mitogen-activated protein kinase/ERK kinases and extracellular signal-regulated kinases in human platelets.
    European journal of biochemistry, 1998, Dec-15, Volume: 258, Issue:3

    Topics: Adult; Blood Platelets; Calcium-Calmodulin-Dependent Protein Kinases; Cytoskeleton; Detergents; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phorbol 12,13-Dibutyrate; Platelet Aggregation; Protein Kinase C; Proto-Oncogene Proteins c-raf; Solubility; Tetradecanoylphorbol Acetate; Thrombin; Thrombopoietin; Time Factors

1998
Biphasic effect of protein kinase C on rat renal cortical Na+, K+-ATPase.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1998, Volume: 49, Issue:4

    Topics: Amiloride; Amphotericin B; Animals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ibuprofen; Kidney Cortex; Male; Oxazines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate

1998
Adhesion of human monocytic THP-1 cells to endothelial cell adhesion molecules or extracellular matrix proteins via beta1 integrins regulates heparin binding epidermal growth factor-like growth factor (HB-EGF) expression.
    European cytokine network, 1999, Volume: 10, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Colforsin; COS Cells; E-Selectin; Endothelium, Vascular; Epidermal Growth Factor; Extracellular Matrix Proteins; Gene Expression Regulation; Heparin; Heparin-binding EGF-like Growth Factor; Humans; Integrin beta1; Intercellular Adhesion Molecule-1; Intercellular Signaling Peptides and Proteins; Monocytes; Phorbol 12,13-Dibutyrate; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Vascular Cell Adhesion Molecule-1

1999
Redox modulation of intracellular free calcium concentration in thyroid FRTL-5 cells: evidence for an enhanced extrusion of calcium.
    The Biochemical journal, 1999, May-01, Volume: 339 ( Pt 3)

    Topics: Animals; Barium; Calcium; Calcium-Transporting ATPases; Cell Line; Enzyme Activation; Hydrogen-Ion Concentration; Imidazoles; Membrane Potentials; Mercaptoethanol; Oxidation-Reduction; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Binding; Protein Kinase C; Rats; Staurosporine; tert-Butylhydroperoxide; Tetradecanoylphorbol Acetate; Thapsigargin; Thimerosal; Thyroid Gland; Vanadates

1999
Regulation of L-type Ca2+ channels in rabbit portal vein by G protein alphas and betagamma subunits.
    The Journal of physiology, 1999, May-15, Volume: 517 ( Pt 1)

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Proteins; In Vitro Techniques; Indoles; Male; Maleimides; Models, Biological; Muscle, Smooth, Vascular; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Portal Vein; Protein Conformation; Protein Kinase C; Pyrroles; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thionucleotides

1999
Regulation of calcium-dependent [3H]noradrenaline release from rat cerebrocortical synaptosomes by protein kinase C and modulation of the actin cytoskeleton.
    Neurochemistry international, 1999, Volume: 34, Issue:3

    Topics: Actins; Animals; Calcium; Cerebral Cortex; Cytoskeleton; Deoxyribonuclease I; Enzyme Inhibitors; Female; Male; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Synaptosomes; Tetradecanoylphorbol Acetate; Tritium

1999
Protein kinase C-alpha produces reciprocal effects on the phorbol ester stimulated tyrosine phosphorylation of a 50 kDa kinase in Jurkat cells.
    Biological chemistry, 1999, Volume: 380, Issue:4

    Topics: Adenosine; Affinity Labels; Cell Extracts; Enzyme Activation; Enzyme Inhibitors; Humans; Isoenzymes; Jurkat Cells; Kinetics; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Substrate Specificity; Tetradecanoylphorbol Acetate; Tyrosine

1999
Phorbol ester modulation of active ion transport across the rabbit conjunctival epithelium.
    Experimental eye research, 1999, Volume: 69, Issue:1

    Topics: Animals; Biological Transport, Active; Bumetanide; Chlorine; Conjunctiva; Culture Techniques; Enzyme Inhibitors; Female; Ion Transport; Male; Ouabain; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rabbits; Staurosporine; Tetradecanoylphorbol Acetate

1999
Inositol hexaphosphate reduces 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase independent of protein kinase C isoform expression in keratinocytes.
    Cancer letters, 1999, Jun-01, Volume: 140, Issue:1-2

    Topics: Animals; Blotting, Western; Cell Division; Cell Line; Dose-Response Relationship, Drug; Enzyme Induction; Epidermis; Female; Humans; Isoenzymes; Keratinocytes; Mice; Mice, Inbred SENCAR; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Phorbol 12,13-Dibutyrate; Phytic Acid; Protein Kinase C; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tetradecanoylphorbol Acetate

1999
Requirement for protein kinase C in reactive oxygen species-induced apoptosis of vascular smooth muscle cells.
    Circulation, 1999, Aug-31, Volume: 100, Issue:9

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Cells, Cultured; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Hydrogen Peroxide; Immunohistochemistry; In Situ Nick-End Labeling; Muscle, Smooth, Vascular; Naphthalenes; Necrosis; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Reactive Oxygen Species; Staurosporine; Tetradecanoylphorbol Acetate

1999
Protein kinase C-delta is a target of B-cell antigen receptor signaling.
    Immunology letters, 1999, Aug-03, Volume: 69, Issue:2

    Topics: Animals; B-Lymphocytes; Biological Transport; Enzyme Activation; Estrenes; Humans; Ionomycin; Isoenzymes; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Phorbol 12,13-Dibutyrate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Processing, Post-Translational; Pyrrolidinones; Receptors, Antigen, B-Cell; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases

1999
The involvement of protein kinase C in the regulation of choline cotransport in Limulus.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 1999, Volume: 123, Issue:3

    Topics: Animals; Arachidonic Acids; Biological Transport; Brain; Carcinogens; Carrier Proteins; Choline; Cholinergic Agents; Enzyme Inhibitors; Hemicholinium 3; Horseshoe Crabs; Nervous System; Organ Culture Techniques; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Potassium Chloride; Protein Kinase C; Quinacrine; Staurosporine; Tetradecanoylphorbol Acetate; Tritium

1999
Protein kinase C and the opposite regulation of sodium channel alpha- and beta1-subunit mRNA levels in adrenal chromaffin cells.
    Journal of neurochemistry, 1999, Volume: 73, Issue:4

    Topics: Adrenal Medulla; Animals; Cattle; Cell Nucleus; Cells, Cultured; Chromaffin Cells; Cycloheximide; Down-Regulation; Enzyme Activation; Gene Expression Regulation; Kinetics; Macromolecular Substances; Phorbol 12,13-Dibutyrate; Protein Kinase C; RNA, Messenger; Sodium Channels; Tetradecanoylphorbol Acetate; Transcription, Genetic

1999
Structural determinants of phorbol ester binding in synaptosomes: pharmacokinetics and pharmacodynamics.
    European journal of pharmacology, 1999, Sep-17, Volume: 381, Issue:1

    Topics: Animals; Binding Sites; Binding, Competitive; Cerebral Cortex; Kinetics; Male; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Binding; Protein Kinase C; Rats; Rats, Sprague-Dawley; Synaptic Membranes; Synaptosomes; Tetradecanoylphorbol Acetate; Time Factors; Tritium

1999
TPA-enhanced motility and invasion in a highly metastatic variant (L-10) of human rectal adenocarcinoma cell line RCM-1: selective role of PKC-alpha and its inhibition by a combination of PDBu-induced PKC downregulation and antisense oligonucleotides trea
    Clinical & experimental metastasis, 1999, Volume: 17, Issue:4

    Topics: Adenocarcinoma; Base Sequence; Carbazoles; Down-Regulation; Humans; Indoles; Isoenzymes; Naphthalenes; Neoplasm Invasiveness; Neoplasm Metastasis; Oligonucleotides, Antisense; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Protein Kinase C-alpha; Rectal Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1999
The lipophilicity of phorbol esters as a critical factor in determining the pattern of translocation of protein kinase C delta fused to green fluorescent protein.
    The Journal of biological chemistry, 2000, Apr-21, Volume: 275, Issue:16

    Topics: Animals; Cell Membrane; CHO Cells; Cricetinae; Green Fluorescent Proteins; Isoenzymes; Lipid Metabolism; Luminescent Proteins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Protein Kinase C-delta; Recombinant Fusion Proteins; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate

2000
Phosphorylation regulates spontaneous and evoked transmitter release at a giant terminal in the rat auditory brainstem.
    The Journal of physiology, 2000, Jul-15, Volume: 526 Pt 2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; Animals; Cochlear Nucleus; Enzyme Inhibitors; Evoked Potentials; Excitatory Postsynaptic Potentials; In Vitro Techniques; Indoles; Maleimides; Phorbol 12,13-Dibutyrate; Phosphorylation; Presynaptic Terminals; Protein Kinase C; Rats; Rats, Wistar; Synaptic Transmission; Tetradecanoylphorbol Acetate

2000
Phorbol ester-regulated cleavage of normal prion protein in HEK293 human cells and murine neurons.
    The Journal of biological chemistry, 2000, Nov-10, Volume: 275, Issue:45

    Topics: Amino Acid Sequence; Animals; Blotting, Western; Bucladesine; Carcinogens; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Humans; Kinetics; Methanol; Mice; Molecular Sequence Data; Neurons; Phorbol 12,13-Dibutyrate; Phorbol Esters; Precipitin Tests; Prions; Protein Isoforms; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Up-Regulation

2000
Properties of the inward-rectifying Cl- channel in rat choroid plexus: regulation by intracellular messengers and inhibition by divalent cations.
    Pflugers Archiv : European journal of physiology, 2000, Volume: 440, Issue:6

    Topics: Adenosine Triphosphate; Animals; Cadmium; Cations, Divalent; Chloride Channels; Choroid Plexus; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Electric Conductivity; Electrodes; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Solutions; Tetradecanoylphorbol Acetate; Zinc

2000
Regulation of conjunctival goblet cell secretion by Ca(2+)and protein kinase C.
    Experimental eye research, 2000, Volume: 71, Issue:6

    Topics: Animals; Blotting, Western; Calcium; Chelating Agents; Conjunctiva; Glycoproteins; Goblet Cells; Ionomycin; Ionophores; Male; Microscopy, Fluorescence; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

2000
Parathyroid hormone-related protein down-regulates bone sialoprotein gene expression in cementoblasts: role of the protein kinase A pathway.
    Endocrinology, 2000, Volume: 141, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Dental Cementum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Integrin-Binding Sialoprotein; Kinetics; Parathyroid Hormone-Related Protein; Phorbol 12,13-Dibutyrate; Proteins; RNA, Messenger; Second Messenger Systems; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Thionucleotides

2000
Activation of dopamine D(1)-like receptor causes phosphorylation of alpha(1)-subunit of Na(+),K(+)-ATPase in rat renal proximal tubules.
    European journal of pharmacology, 2001, Jan-05, Volume: 411, Issue:1-2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Cell Line; Dopamine Agonists; Enzyme Inhibitors; In Vitro Techniques; Kidney Tubules, Proximal; Male; Mutation; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tetradecanoylphorbol Acetate

2001
Regulation of adenohypophyseal pyroglutamyl aminopeptidase II activity by thyrotropin-releasing hormone and phorbol esters.
    Endocrine, 2000, Volume: 13, Issue:3

    Topics: Aminopeptidases; Animals; Cells, Cultured; Cyclic AMP; Female; Homeostasis; Male; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pituitary Gland, Anterior; Protein Kinase C; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Sex Characteristics; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Triiodothyronine

2000
Constitutive alpha-secretase cleavage of the beta-amyloid precursor protein in the furin-deficient LoVo cell line: involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10.
    Journal of neurochemistry, 2001, Volume: 76, Issue:5

    Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Cell Line; Endopeptidases; Furin; Humans; Kinetics; Phorbol 12,13-Dibutyrate; Proprotein Convertases; Protein Kinase C; Recombinant Proteins; Subtilisins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

2001
G-protein-coupled receptor stimulation of the p42/p44 mitogen-activated protein kinase pathway is attenuated by lipid phosphate phosphatases 1, 1a, and 2 in human embryonic kidney 293 cells.
    The Journal of biological chemistry, 2001, Apr-20, Volume: 276, Issue:16

    Topics: Cell Line; Cell Membrane; GTP-Binding Proteins; Humans; Isoenzymes; Kidney; Kinetics; Lysophospholipids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phorbol 12,13-Dibutyrate; Phosphatidate Phosphatase; Phosphatidic Acids; Phospholipase D; Receptors, Cell Surface; Recombinant Proteins; Sphingosine; Substrate Specificity; Tetradecanoylphorbol Acetate; Transfection; Virulence Factors, Bordetella

2001
Phorbol esters promote postsynaptic accumulation of Vesl-1S/Homer-1a protein.
    The European journal of neuroscience, 2001, Volume: 13, Issue:7

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alternative Splicing; Animals; Anisomycin; Carcinogens; Carrier Proteins; Cells, Cultured; Excitatory Amino Acid Antagonists; Hippocampus; Homer Scaffolding Proteins; Microscopy, Immunoelectron; Neurons; Neuropeptides; Phorbol 12,13-Dibutyrate; Potassium; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Synaptic Membranes; Tetradecanoylphorbol Acetate; Tetrodotoxin

2001
Deterioration of the protein kinase C-K(ATP) channel pathway in regulation of coronary flow in hypercholesterolaemic rabbits.
    European journal of pharmacology, 2001, Apr-27, Volume: 418, Issue:3

    Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Enzyme Inhibitors; Heart Ventricles; Hypercholesterolemia; In Vitro Techniques; Male; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C; Rabbits; Staurosporine; Tetradecanoylphorbol Acetate

2001
Diacylglycerol (DAG)-lactones, a new class of protein kinase C (PKC) agonists, induce apoptosis in LNCaP prostate cancer cells by selective activation of PKCalpha.
    The Journal of biological chemistry, 2002, Jan-04, Volume: 277, Issue:1

    Topics: Apoptosis; Diglycerides; Enzyme Inhibitors; Humans; Isoenzymes; Lactones; Male; Phorbol 12,13-Dibutyrate; Prostatic Neoplasms; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2002
Activity of protein kinase C modulates the apoptosis induced by polychlorinated biphenyls in human leukemic HL-60 cells.
    Toxicology letters, 2002, Sep-05, Volume: 135, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Chlorodiphenyl (54% Chlorine); Diglycerides; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Inhibitors; HL-60 Cells; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate

2002
Modulation of the human protein kinase C alpha gene promoter by activator protein-2.
    Biochemistry, 2002, Oct-01, Volume: 41, Issue:39

    Topics: 5' Untranslated Regions; Base Sequence; Cloning, Molecular; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Isoenzymes; Molecular Sequence Data; Phorbol 12,13-Dibutyrate; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C-alpha; Second Messenger Systems; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transcription Factor AP-2; Transcription Factors; Transcription Initiation Site; Transfection; Tumor Cells, Cultured

2002
Prolactin signaling in porcine adrenocortical cells: involvement of protein kinases.
    Domestic animal endocrinology, 2002, Volume: 23, Issue:4

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Androstenedione; Animals; Diglycerides; Enzyme Activators; Enzyme Inhibitors; Female; Genistein; Hydrocortisone; Ionomycin; Phorbol 12,13-Dibutyrate; Prolactin; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Sphingosine; Swine; Tetradecanoylphorbol Acetate

2002
Protein kinase C-mediated Ca2+ entry in HEK 293 cells transiently expressing human TRPV4.
    British journal of pharmacology, 2003, Volume: 140, Issue:2

    Topics: Calcium; Cation Transport Proteins; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Humans; Hypotonic Solutions; Indoles; Ion Channels; Maleimides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; TRPV Cation Channels

2003
Mechanisms of arginine-vasopressin-induced Ca2+ oscillations in beta-cells (HIT-T15): a role for oscillating protein kinase C.
    Endocrinology, 2004, Volume: 145, Issue:10

    Topics: Animals; Arginine Vasopressin; Biological Transport; Calcium; Calcium Channels; Cell Line; Enzyme Activation; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; Islets of Langerhans; Isoenzymes; Oscillometry; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate

2004
Activation of arylalkylamine N-acetyltransferase by phorbol esters in bovine pinealocytes suggests a novel regulatory pathway in melatonin synthesis.
    Journal of neuroendocrinology, 2004, Volume: 16, Issue:9

    Topics: Animals; Arylalkylamine N-Acetyltransferase; Calcium Signaling; Cattle; Cyclic AMP; Enzyme Activation; Female; Male; Melatonin; Organ Culture Techniques; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pineal Gland; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate

2004
Bidirectional regulation of renal cortical Na+,K+-ATPase by protein kinase C.
    Acta biochimica Polonica, 2004, Volume: 51, Issue:3

    Topics: Amiloride; Animals; Arachidonic Acids; Brefeldin A; Cytochrome P-450 Enzyme System; Endocytosis; Enzyme Activation; Enzyme Inhibitors; Kidney Cortex; Kinetics; Male; Models, Biological; Nocodazole; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositol 3-Kinases; Protein Kinase C; Rats; Rats, Wistar; Sodium; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tetradecanoylphorbol Acetate

2004
Role of phorbol ester localization in determining protein kinase C or RasGRP3 translocation: real-time analysis using fluorescent ligands and proteins.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:1

    Topics: Animals; Biological Transport; CHO Cells; Cricetinae; Fluorescent Dyes; Guanine Nucleotide Exchange Factors; Humans; Kinetics; Ligands; Microscopy, Confocal; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Transport; ras Guanine Nucleotide Exchange Factors; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate

2005
Individual C1 domains of PKD3 in phorbol ester-induced plasma membrane translocation of PKD3 in intact cells.
    Cellular signalling, 2005, Volume: 17, Issue:11

    Topics: Animals; Catalysis; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Enzyme Activation; Enzyme Inhibitors; Mutation; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Structure, Tertiary; Protein Transport; Radioligand Assay; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate

2005
Enhancement of cisplatin sensitivity of cisplatin-resistant human cervical carcinoma cells by bryostatin 1.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Sep-15, Volume: 11, Issue:18

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Bryostatins; Caspase 3; Caspases; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Female; HeLa Cells; Humans; Indoles; Lactams; Macrolides; Phorbol 12,13-Dibutyrate; Poly(ADP-ribose) Polymerases; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; RNA Interference; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Transfection; Uterine Cervical Neoplasms

2005
Functional characterization of a human organic anion transporter hOAT4 in placental BeWo cells.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2006, Volume: 27, Issue:5

    Topics: Cell Line; Dehydroepiandrosterone Sulfate; Enzyme Activation; Estradiol; Estrone; Humans; Kinetics; Organic Anion Transporters, Sodium-Independent; Phorbol 12,13-Dibutyrate; Placenta; Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection

2006
Directional sensing of a phorbol ester gradient requires CD44 and is regulated by CD44 phosphorylation.
    Oncogene, 2006, Nov-30, Volume: 25, Issue:56

    Topics: Amino Acid Sequence; Cell Line, Tumor; Chemotaxis; Cyclic AMP-Dependent Protein Kinases; Humans; Hyaluronan Receptors; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Serine; Signal Transduction; Tetradecanoylphorbol Acetate

2006
Cytotoxic action of phorbol esters on human pancreatic cancer cells.
    International journal of cancer, 2007, Oct-01, Volume: 121, Issue:7

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Inhibitory Concentration 50; Intracellular Signaling Peptides and Proteins; Maleimides; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Pancreatic Neoplasms; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Xenograft Model Antitumor Assays

2007
Differential roles of PKCalpha and PKCepsilon in controlling the gene expression of Nox4 in human endothelial cells.
    Free radical biology & medicine, 2008, Apr-15, Volume: 44, Issue:8

    Topics: Cells, Cultured; Down-Regulation; Endothelial Cells; Gene Expression Regulation; Humans; NADPH Oxidase 4; NADPH Oxidases; Phorbol 12,13-Dibutyrate; Protein Kinase C-alpha; Protein Kinase C-epsilon; RNA, Small Interfering; Superoxides; Tetradecanoylphorbol Acetate; Umbilical Veins; Up-Regulation

2008
Two PKC consensus sites on human acid-sensing ion channel 1b differentially regulate its function.
    American journal of physiology. Cell physiology, 2009, Volume: 296, Issue:2

    Topics: Acid Sensing Ion Channels; Amino Acid Sequence; Animals; Benzophenanthridines; Consensus Sequence; Enzyme Activation; Enzyme Activators; Humans; Ion Channel Gating; Kinetics; Membrane Potentials; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Oocytes; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Conformation; Protein Kinase C; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Sodium Channels; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Xenopus laevis

2009
Does PKC activation increase the homologous desensitization of μ opioid receptors?
    British journal of pharmacology, 2015, Volume: 172, Issue:2

    Topics: Analgesics, Opioid; Animals; Brain; Enkephalin, Methionine; HEK293 Cells; Humans; Male; Mice, Transgenic; Morphine; Muscarine; Neurons; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Transport; Rats, Sprague-Dawley; Receptors, Opioid, mu; Tetradecanoylphorbol Acetate

2015
Vasorelaxing Effect of Resveratrol on Bovine Retinal Arteries.
    Investigative ophthalmology & visual science, 2016, Volume: 57, Issue:4

    Topics: Animals; Antioxidants; Cattle; Dose-Response Relationship, Drug; Endothelium, Vascular; Isometric Contraction; Muscle, Smooth, Vascular; Myography; Nitric Oxide; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C; Resveratrol; Retinal Artery; Stilbenes; Tetradecanoylphorbol Acetate; Vasodilation; Vasodilator Agents

2016