phorbol 12,13-dibutyrate has been researched along with sq-23377 in 114 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (25.44) | 18.7374 |
| 1990's | 68 (59.65) | 18.2507 |
| 2000's | 16 (14.04) | 29.6817 |
| 2010's | 1 (0.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anastassiou, ED; Balow, J; Boumpas, DT; Mond, JJ; Thyphronitis, G; Tsokos, GC; Yamada, H | 1 |
| Alexandre, A; Deana, R; Donella-Deana, A; Francesconi, M; Ruzzene, M | 1 |
| Akhtar, RA; Wilmoth, TL | 1 |
| Goto, K; Kasuya, Y; Masaki, T; Morimoto, H; Nakauchi, H; Sakurai, T; Takuwa, Y | 1 |
| Cattaneo, MG; Magrini, L; Sparber, SB; Vicentini, LM | 1 |
| Li, F; McCrady, CW; McVicar, DW; Merchant, RE | 1 |
| Franklin, RA; Gelfand, EW; Lucas, JJ; Szepesi, A; Takase, K; Terada, N | 1 |
| Bear, HD; Bethke, KP; Inge, TH; McCrady, CM; Tuttle, TM | 1 |
| Courtney, MJ; Nicholls, DG | 1 |
| Freeman, JW; Hamby, LS; McGrath, PC | 2 |
| Peterson, MW; Walter, ME | 1 |
| Bryant, A; Farrant, J; Franz, A; Webster, AD | 1 |
| Gelfand, EW; Or, R; Tordai, A | 1 |
| Bast, A; Brozius, MM; Jansen, W; Leurs, R; Smit, MJ; Timmerman, H | 1 |
| Burgess, GM; Coote, PR; Dunn, PM; Rang, HP; Wood, JN | 1 |
| Betzler, M; Meuer, SC; Qiao, L; Schürmann, G | 1 |
| Cantrell, DA; Clipstone, NA; Hivroz-Burgaud, C | 1 |
| Brunswick, M; Mond, JJ; Samelson, LE | 1 |
| Callard, RE; Rigley, KP; Thurstan, SM | 1 |
| Davis, DF; McVicar, DW; Merchant, RE | 1 |
| McCrady, CW; McVicar, DW; Merchant, RE | 1 |
| Elitsur, Y; Luk, GD | 1 |
| Brines, RD; Klaus, GG | 1 |
| Bryant, A; Farrant, J; Franz, A | 1 |
| Urban, ND; Zier, KS | 1 |
| Peterson, MW; Shasby, DM; Winter, MC | 1 |
| Auffredou, MT; Chaouchi, N; Galanaud, P; Leca, G; Sharma, S; Taieb, J; Vazquez, A | 1 |
| Barras, C; Capasso, P; Miescher, S; Qiao, L; Stoeck, M; von Fliedner, V | 1 |
| Harootunian, AT; Kao, JP; Paranjape, S; Tsien, RY | 1 |
| Braquet, P; Ferber, E; Fischer, G; Harell, T; Her, E; Naor, Z; Reiss, N; Zor, U | 1 |
| Feuerstein, N; Francis, ML; Lindsberg, ML; Mond, JJ; Tung, L | 1 |
| Antoni, FA; Dayanithi, G | 1 |
| Jacobson, DP; O'Flaherty, JT; Redman, JF; Rossi, AG | 1 |
| Boscá, L; Díaz-Guerra, MJ | 1 |
| Bhat, NK; Fisher, RJ; Fujiwara, S; June, CH; Koizumi, S; Lindsten, T; Papas, TS; Thompson, CB | 1 |
| Crowley, NJ; Darrow, TL; Quinn-Allen, MA; Seigler, HF | 1 |
| Larsen, CS | 1 |
| Bedell, K; Shasby, DM; Wilson, JS; Winter, M | 1 |
| Merritt, JE; Rubin, RP | 1 |
| Hai, CM; Murphy, RA; Ratz, PH | 1 |
| Edgeworth, J; Freemont, P; Hogg, N | 1 |
| Cantrell, DA; Crumpton, MJ; Davies, AA; Friedrich, B; Gullberg, M | 1 |
| Ailhaud, G; Gaillard, D; Lagarde, M; Négrel, R | 1 |
| Matuoka, K; Nagai, Y; Suzuki-Sekimori, R; Takenawa, T | 1 |
| Bauer, KD; Dunn, MM; Kamp, DW; Knap, A | 1 |
| Alexander, RW; Griendling, KK; Tsuda, T | 1 |
| Brown, JH; Trilivas, I | 1 |
| Flores-Romo, L; Foster, D; Gordon, J; Guy, GR | 1 |
| Carchman, RA; Dunn, NL; Massey, GV; McCrady, CW; Russell, EC | 1 |
| Holman, M; Klaus, GG; Vondy, K | 1 |
| DeFranco, AL; Page, DM | 1 |
| Cairns, JA; Gillis, S; Gordon, J; Guy, GR; Millsum, MJ | 1 |
| Brown, G; Gordon, J; Guy, GR; Michell, RH | 1 |
| Abdel-Latif, AA; Akhtar, RA; Howe, PH; Naderi, S | 1 |
| Kaibuchi, K; Kikuchi, A; Takai, Y; Tanimoto, T; Tsuda, T; Yamashita, T | 1 |
| Cantrell, DA; Crumpton, MJ; Davies, AA; Hexham, JM; Parker, PJ; Rothbard, J | 1 |
| Benedict, SH; Gelfand, EW; Kumagai, N; Mills, GB | 4 |
| Balazovich, KJ; Boxer, LA | 1 |
| Carchman, RA; Ely, CM; McCrady, CW; Westin, E | 1 |
| Gordon, J; Guy, GR; Millsum, MJ | 1 |
| Hirning, LD; Matthies, HJ; Miller, RJ; Palfrey, HC | 1 |
| Gordon, J; Guy, GR; Ledbetter, JA; Millsum, MJ | 1 |
| Aub, DL; Leslie, BA; McKinney, JS; Putney, JW | 1 |
| Chapman, DA; Godfrey, PP; Putney, JW; Rubin, RP | 1 |
| Gelfand, EW; Lucas, JJ; Takase, K; Terada, N | 1 |
| Boise, LH; Choi, MS; Gottschalk, AR; Klaus, GG; Quintans, J; Thompson, CB | 1 |
| Orth, DN; Won, JG | 1 |
| Cronin, KC; Gansbacher, B; Salvadori, S; Zier, KS | 1 |
| Burgess, GM; Davis, C; Harvey, JS; James, IF | 1 |
| Kamath, JM; Moy, AB; Shasby, DM; Shasby, SS | 1 |
| Johnson, MS; Mitchell, R; Noble, J; Wolbers, WB | 1 |
| Mayer, E; Sun, XP; Supplisson, S | 1 |
| Fennell, M; Johnson, MS; Mitchell, R; Noble, J; Wolbers, WB | 1 |
| Boulla, G; Gourdji, D; Passegue, E; Richard, JL | 1 |
| Austin, LM; Bunn, SJ; Dunkley, PR; Herd, LM; Sim, AT | 1 |
| Bahl, AK; Foreman, JC | 1 |
| Smith, RD | 1 |
| Benedict, SH; Chan, MA; Shu, J | 1 |
| Gelfand, EW; Or, R; Renz, H; Terada, N | 1 |
| Burgstahler, AD; Mani, A; Moyer, MS; Nathanson, MH; Orloff, JJ | 1 |
| Mitchell, R; Thomson, FJ | 1 |
| Bajnath, RB; De Jonge, HR; Groot, JA; van den Berghe, N | 1 |
| Ching, KN; Nicholson, WE; Orth, DN; Won, JG | 1 |
| Johnson, MS; MacEwan, DJ; Mitchell, R; Thomson, FJ | 1 |
| Autschbach, F; Meuer, SC; Qiao, L; Schirren, A; Schürmann, G; Wallich, R | 1 |
| Corso, M; Horwitz, J; Passarello, B | 1 |
| Ciereszko, RE; Guan, Z; Ottobre, AC; Ottobre, JS; Petroff, BK; Stokes, BT | 2 |
| Denis, M; Hanon, E; Keil, G; Lyaku, S; Pastoret, PP; Vanderplasschen, A | 1 |
| Groen, AK; Klinkspoor, JH; Lee, SP; Tytgat, GN | 1 |
| Cruchley, AT; Paleolog, E; Taichman, NS; Taylor, P; Young, S | 1 |
| Ivanova, AE; Marakhova, II; Toropova, FV; Vereninov, AA; Vinogradova, TA | 1 |
| Barbazuk, SM; Gold, MR | 1 |
| Bastien, Y; Mazer, BD; Zhuang, Q | 1 |
| Dartt, DA; Hodges, RR; Kanno, H; Ralda, N; Rawe, IM; Rios, JD; Rios, JR; Zieske, JD; Zoukhri, D | 1 |
| Bajnath, RB; Bouritius, H; Groot, JA; Oprins, JC | 1 |
| Marakhova, II; Toropova, FV; Vinogradova, TA | 1 |
| Nauwynck, HJ; Pensaert, MB; van der Meulen, KM | 1 |
| Ciereszko, RE; Dusza, L; Kaminska, B; Opalka, M | 1 |
| Bhattacharyya, RS; Radeff, JM; Singh, AT; Stern, PH | 1 |
| Nozu, F; Tsunoda, Y; Yoshida, H | 1 |
| Baier, G; Böck, G; Gruber, T; Leitges, M; Thuille, N | 1 |
| Cuadra, AE; El-Fakahany, EE | 1 |
| Aksenov, N; Karitskaya, I; Marakhova, I; Vinogradova, T; Zenin, V | 1 |
| Akaishi, E; Hosaka, K; Kubohara, Y; Okamura, S; Tanaka, S | 1 |
| Adachi, M; Minoguchi, K; Oda, N; Ohta, S; Okada, S; Samson, KT; Tanaka, A; Watanabe, Y; Yamamoto, M; Yamamoto, Y; Yokoe, T | 1 |
| Aksenov, ND; Karitskaia, IA; Khaĭdukova, AL; Marakhova, II; Zenin, VV | 1 |
| Li, LP; Teng, ZP; Wang, T; Xing, FY | 1 |
| Bortell, R; Greiner, DL; Jurczyk, A; Lidstone, EA; Mordes, JP; O'Sullivan-Murphy, B; Pino, SC; Rossini, AA; Thornley, TB; Urano, F | 1 |
| Di, J; Hao, W; Liu, J; Wang, Y; Xing, F; Xing, R; Zeng, S | 1 |
114 other study(ies) available for phorbol 12,13-dibutyrate and sq-23377
| Article | Year |
|---|---|
Cholera toxin promotes the proliferation of anti-mu antibody-prestimulated human B cells.
Topics: Antibodies, Monoclonal; B-Lymphocytes; Cell Division; Cells, Cultured; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Interleukin-4; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate | 1992 |
The antioxidant butylated hydroxytoluene (BHT) inhibits the dioctanoylglycerol-evoked platelet response but potentiates that elicited by ionomycin.
Topics: Adenosine Triphosphate; Alkaloids; Arachidonic Acid; Blood Platelets; Butylated Hydroxytoluene; Diglycerides; Drug Synergism; Humans; In Vitro Techniques; Ionomycin; Kinetics; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Staurosporine | 1992 |
Phorbol esters inhibit ionomycin-induced hydrolysis of phosphoinositides and phosphatidylcholine in bovine corneal epithelial cells.
Topics: Animals; Cattle; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cornea; Enzyme Activation; Epithelium; Hydrolysis; Ionomycin; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Level of ETB receptor mRNA is down-regulated by endothelins through decreasing the intracellular stability of mRNA molecules.
Topics: Animals; Blotting, Northern; Cell Line; Endothelins; Gene Expression Regulation, Neoplastic; Ionomycin; Kinetics; Osteosarcoma; Phorbol 12,13-Dibutyrate; Rats; Receptors, Cell Surface; Receptors, Endothelin; RNA, Messenger; RNA, Neoplasm | 1992 |
Interaction between mitogens upon intracellular Ca2+ pools in murine fibroblasts.
Topics: 3T3 Cells; Animals; Bombesin; Bradykinin; Calcium; Calcium Channels; Drug Interactions; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ion Channel Gating; Ionomycin; Mice; Phorbol 12,13-Dibutyrate; Platelet-Derived Growth Factor; Signal Transduction; Stimulation, Chemical; Terpenes; Thapsigargin; Vasopressins | 1992 |
A comparison of serum-free media for the support of in vitro mitogen-induced blastogenic expansion of cytolytic lymphocytes.
Topics: Blood; Cells, Cultured; Culture Media; Humans; Ionomycin; Killer Cells, Lymphokine-Activated; Lymphocyte Activation; Lymphocytes; Mitogens; Phorbol 12,13-Dibutyrate; Phytohemagglutinins | 1991 |
Rapamycin inhibits the phosphorylation of p70 S6 kinase in IL-2 and mitogen-activated human T cells.
Topics: Amino Acid Sequence; Antibodies; Cell Line; Cells, Cultured; Cyclosporine; Ethers, Cyclic; Humans; Immunoblotting; Immunosuppressive Agents; Interleukin-2; Ionomycin; Lymphocyte Activation; Molecular Sequence Data; Okadaic Acid; Peptides; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Phosphorylation; Phytohemagglutinins; Polyenes; Protein Kinase Inhibitors; Recombinant Proteins; Ribosomal Protein S6; Ribosomal Protein S6 Kinases; Ribosomal Proteins; Sirolimus; T-Lymphocytes; Tacrolimus | 1992 |
Activation of CD8+ murine T cells from tumor-draining lymph nodes by phorbol dibutyrate plus calcium ionophore.
Topics: Animals; Cells, Cultured; Cytotoxicity Tests, Immunologic; Female; Immunophenotyping; Immunotherapy, Adoptive; Ionomycin; Lymph Nodes; Lymphocyte Activation; Lymphocyte Depletion; Mice; Mice, Inbred C57BL; Phorbol 12,13-Dibutyrate; Remission Induction; Sarcoma, Experimental; T-Lymphocytes, Regulatory; Time Factors | 1992 |
Interactions between phospholipase C-coupled and N-methyl-D-aspartate receptors in cultured cerebellar granule cells: protein kinase C mediated inhibition of N-methyl-D-aspartate responses.
Topics: Animals; Cells, Cultured; Cerebellum; Drug Interactions; Granulocytes; Ionomycin; Membrane Potentials; N-Methylaspartate; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Type C Phospholipases | 1992 |
Phorbol dibutyrate plus ionomycin improves the generation of cytotoxic T cells from draining lymph nodes of patients with advanced head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Division; Cytotoxicity Tests, Immunologic; Head and Neck Neoplasms; Humans; Immunotherapy, Adoptive; Ionomycin; Lymph Nodes; Lymphatic Metastasis; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 1992 |
Calcium-activated phosphatidylcholine-specific phospholipase C and D in MDCK epithelial cells.
Topics: Animals; Calcium; Cations; Cell Line; Diglycerides; Dogs; Enzyme Activation; Epithelial Cells; Epithelium; Extracellular Space; Ionomycin; Kidney; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Phospholipase D; Type C Phospholipases | 1992 |
Effect of 12,13-phorbol dibutyrate and ionomycin on defective B cells in common variable immunodeficiency.
Topics: B-Lymphocytes; Cells, Cultured; Dysgammaglobulinemia; Humans; IgG Deficiency; Immunoglobulin G; Immunoglobulin M; Interleukin-2; Interleukin-4; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Protein Kinase C | 1992 |
Effects of changes in membrane potential on the cyclosporin-induced inhibition of T-cell proliferation.
Topics: Cell Division; Cyclosporine; Humans; Ionomycin; Lymphocyte Activation; Membrane Potentials; Phorbol 12,13-Dibutyrate; Phytohemagglutinins; T-Lymphocytes; Valinomycin | 1992 |
Is protein kinase C involved in histamine H1-receptor desensitization?
Topics: Animals; Cyclic GMP; Drug Tolerance; Guinea Pigs; Histamine; Ionomycin; Jejunum; Kinetics; Lung; Male; Methacholine Chloride; Muscle Contraction; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Histamine H1 | 1991 |
Bradykinin evoked depolarization of a novel neuroblastoma x DRG neurone hybrid cell line (ND7/23).
Topics: Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcium; Cell Membrane; Cells, Cultured; Cytosol; Evoked Potentials; Ganglia, Spinal; Hybrid Cells; Inositol Phosphates; Ionomycin; Membrane Potentials; Neuroblastoma; Neurons; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Receptors, Bradykinin; Receptors, Neurotransmitter; Second Messenger Systems; Staurosporine | 1991 |
Down-regulation of protein kinase C activation in human lamina propria T lymphocytes: influence of intestinal mucosa on T cell reactivity.
Topics: Antigens; Antigens, Differentiation, T-Lymphocyte; Calcium; CD2 Antigens; CD3 Complex; Enzyme Activation; Humans; In Vitro Techniques; Intestinal Mucosa; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Immunologic; Signal Transduction; T-Lymphocytes | 1991 |
Signaling requirements for the expression of the transactivating factor NF-AT in human T lymphocytes.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcium; CD2 Antigens; CD3 Complex; Cell Nucleus; DNA-Binding Proteins; Gene Expression Regulation; Humans; In Vitro Techniques; Inositol Phosphates; Interleukin-2; Ionomycin; Lymphocyte Activation; Nuclear Proteins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Immunologic; Signal Transduction; T-Lymphocytes; Time Factors | 1991 |
Surface immunoglobulin crosslinking activates a tyrosine kinase pathway in B cells that is independent of protein kinase C.
Topics: Animals; Antibodies, Monoclonal; B-Lymphocytes; Blotting, Western; Cross-Linking Reagents; Ionomycin; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Spleen; Tyrosine | 1991 |
Independent regulation of interleukin 4 (IL-4)-induced expression of human B cell surface CD23 and IgM: functional evidence for two IL-4 receptors.
Topics: Antigens, CD19; Antigens, Differentiation, B-Lymphocyte; Antigens, Surface; B-Lymphocytes; Dose-Response Relationship, Drug; Humans; Immunoglobulin M; Interleukin-4; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Receptors, Fc; Receptors, IgE; Receptors, Interleukin-4; Receptors, Mitogen; Signal Transduction | 1991 |
In vitro analysis of the proliferative potential of T cells from patients with brain tumor: glioma-associated immunosuppression unrelated to intrinsic cellular defect.
Topics: Adrenal Cortex Hormones; Adult; Aged; Brain Neoplasms; Female; Glioma; Humans; Immune Tolerance; Interleukin-2; Ionomycin; Lymphocyte Activation; Male; Middle Aged; Phorbol 12,13-Dibutyrate; Phytohemagglutinins; Receptors, Interleukin-2; Recombinant Proteins; T-Lymphocytes; Tumor Cells, Cultured | 1992 |
Corticosteroids inhibit the delivery of short-term activational pulses of phorbol ester and calcium ionophore to human peripheral T cells.
Topics: Adrenal Cortex Hormones; Bryostatins; Calcium; Cell Division; Dexamethasone; Drug Interactions; Enzyme Activation; Humans; Interleukin-2; Ionomycin; Lactones; Lymphocyte Activation; Macrolides; Mifepristone; Monocytes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Second Messenger Systems; T-Lymphocytes; Time Factors | 1992 |
The inhibition effect of cholecystokinin in human colonic lamina propria lymphocyte proliferation, and reversal by the cholecystokinin receptor antagonist L-364718.
Topics: Adult; Aged; Aged, 80 and over; Benzodiazepinones; Cell Division; Cholecystokinin; Colon; Culture Techniques; Devazepide; DNA; Humans; Intestinal Mucosa; Ionomycin; Lymphocyte Activation; Lymphocytes; Middle Aged; Phorbol 12,13-Dibutyrate; Thymidine | 1991 |
Effects of anti-immunoglobulin antibodies, interleukin-4 and second messenger agonists on B cells from neonatal mice.
Topics: Animals; Animals, Newborn; Antibodies, Anti-Idiotypic; B-Lymphocytes; Cell Differentiation; Cells, Cultured; Drug Interactions; Enzyme Activation; Immunologic Capping; Interleukin-4; Ionomycin; Lymphocyte Activation; Lymphokines; Mice; Mice, Inbred CBA; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Antigen, B-Cell; Receptors, Immunologic; Second Messenger Systems; Specific Pathogen-Free Organisms | 1991 |
Interleukin-2-induced DNA synthesis and immunoglobulin secretion by resting human tonsillar B cells: effects of protein kinase C activation.
Topics: B-Lymphocytes; Cells, Cultured; Colforsin; DNA; Enzyme Activation; Humans; Immunoglobulin G; Immunoglobulin M; Interleukin-2; Interleukin-6; Ionomycin; Lymphocyte Activation; Palatine Tonsil; Phorbol 12,13-Dibutyrate; Protein Kinase C | 1991 |
Negative signal transmission through class II molecules on activated T cells.
Topics: Antibodies, Monoclonal; Cells, Cultured; DNA Replication; Dose-Response Relationship, Immunologic; HLA Antigens; HLA-D Antigens; Humans; Interleukin-2; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Receptors, Interleukin-2; Recombinant Proteins; Signal Transduction; T-Lymphocytes | 1991 |
Synergistic effects of a calcium ionophore and activators of protein kinase C on epithelial paracellular permeability.
Topics: Airway Resistance; Animals; Calcium; Cattle; Cell Membrane Permeability; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Epithelium; Hydrolysis; Ionomycin; Mannitol; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Spectrometry, Fluorescence | 1991 |
Differential inhibition of interleukin 2- and interleukin 4-mediated human B cell proliferation by ionomycin: a possible regulatory role for apoptosis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; B-Lymphocytes; Calcium; Cell Death; DNA Damage; Humans; In Vitro Techniques; Interleukin-2; Interleukin-4; Interleukin-6; Ionomycin; Isoquinolines; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C | 1991 |
Stimulation of FACS-analysed CD4+ and CD8+ human tumour-infiltrating lymphocytes with ionomycin + phorbol-12,13-dibutyrate does not overcome their proliferative deficit.
Topics: CD4-Positive T-Lymphocytes; Cell Separation; Flow Cytometry; Humans; Ionomycin; Lymphocyte Activation; Neoplasms; Phorbol 12,13-Dibutyrate; T-Lymphocytes, Cytotoxic | 1990 |
Generation of calcium oscillations in fibroblasts by positive feedback between calcium and IP3.
Topics: Caffeine; Calcium; Cell Line; Cytosol; Feedback; Fibroblasts; Heparin; Inositol 1,4,5-Trisphosphate; Ionomycin; Periodicity; Phorbol 12,13-Dibutyrate; Protein Kinase C; Ryanodine; Type C Phospholipases | 1991 |
Arachidonic acid release by basophilic leukemia cells and macrophages stimulated by Ca2+ ionophores, antigen and diacylglycerol: essential role for protein kinase C and prevention by glucocorticosteroids.
Topics: Alkaloids; Animals; Antigens; Arachidonic Acids; Calcimycin; Carbazoles; Cell Line; Cell Membrane; Cells, Cultured; Dexamethasone; Immunoglobulin E; Indole Alkaloids; Ionomycin; Kinetics; Leukemia, Basophilic, Acute; Leukemia, Experimental; Macrophages; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Protein Kinase C; Rats; Serum Albumin, Bovine; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Identification of a prominent 85-kDa cAMP-dependent phosphoprotein associated with late G1 phase in mitogen-stimulated B lymphocytes.
Topics: Animals; B-Lymphocytes; Catalysis; Colforsin; Cyclic AMP; Electrophoresis, Gel, Two-Dimensional; G1 Phase; Ionomycin; Mice; Mitogens; Molecular Weight; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Protein Kinases | 1991 |
Evidence for distinct glucocorticoid and guanine 3',5'-monophosphate-effected inhibition of stimulated adrenocorticotropin release in vitro.
Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Corticosterone; Corticotropin-Releasing Hormone; Cyclic GMP; Glucocorticoids; Ionomycin; Phorbol 12,13-Dibutyrate; Pituitary Gland, Anterior; Potassium | 1990 |
Translocation of protein kinase C in human polymorphonuclear neutrophils. Regulation by cytosolic Ca2(+)-independent and Ca2(+)-dependent mechanisms.
Topics: Binding, Competitive; Caenorhabditis elegans Proteins; Calcimycin; Calcium; Carrier Proteins; Cell Membrane; Cytosol; Diglycerides; Humans; Ionomycin; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol 12,13-Dibutyrate; Phospholipids; Protein Kinase C; Receptors, Drug; Sphingosine | 1990 |
Lack of translocation of protein kinase C from the cytosol to the membranes in vasopressin-stimulated hepatocytes.
Topics: Animals; Calcium; Cell Membrane; Cytosol; Diglycerides; Ionomycin; Kinetics; Liver; Male; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Phosphorylase a; Protein Kinase C; Rats; Rats, Inbred Strains; Vasopressins | 1990 |
Reciprocal expression of human ETS1 and ETS2 genes during T-cell activation: regulatory role for the protooncogene ETS1.
Topics: Calcium; Cells, Cultured; DNA Probes; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation; Genes, Regulator; Humans; Ionomycin; Lymphocyte Activation; Models, Biological; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Protein c-ets-2; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Proto-Oncogenes; Repressor Proteins; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Transcription, Genetic | 1990 |
Modulation of in vitro autologous melanoma-specific cytotoxic T-cell responses by phorbol dibutyrate and ionomycin.
Topics: Antigens, CD; Cell Line; Concanavalin A; Cytotoxicity, Immunologic; Humans; Interleukin-2; Ionomycin; Melanoma; Phorbol 12,13-Dibutyrate; T-Lymphocytes, Cytotoxic | 1990 |
Activation of human T lymphocytes by phorbol-12,13-dibutyrate and ionomycin.
Topics: Antibodies, Monoclonal; Calcium; Drug Synergism; Humans; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Phytohemagglutinins; Protein Kinase C; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
The conductance of cultured epithelial cell monolayers: oxidants, adenosine triphosphate, and phorbol dibutyrate.
Topics: Adenosine Triphosphate; Animals; Antimycin A; Calcium; Cell Line; Cell Membrane; Cell Membrane Permeability; Deoxyglucose; Dogs; Electric Conductivity; Epithelium; Hydrogen Peroxide; Ionomycin; Kidney; Kinetics; Phorbol 12,13-Dibutyrate | 1990 |
Pancreatic amylase secretion and cytoplasmic free calcium. Effects of ionomycin, phorbol dibutyrate and diacylglycerols alone and in combination.
Topics: Amylases; Animals; Calcium; Carbachol; Ceruletide; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Ethers; Ionomycin; Ionophores; Male; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Rats, Inbred Strains | 1985 |
Dependence of stress on cross-bridge phosphorylation in vascular smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Ethers; Histamine; Ionomycin; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Myosins; Phorbol 12,13-Dibutyrate; Phosphoproteins; Potassium; Swine | 1989 |
Ionomycin-regulated phosphorylation of the myeloid calcium-binding protein p14.
Topics: Amino Acid Sequence; Calcium; Calcium-Binding Proteins; Electrophoresis, Gel, Two-Dimensional; Humans; Ionomycin; Molecular Sequence Data; Monocytes; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphotyrosine; Signal Transduction; Tyrosine | 1989 |
Evidence that a kinase distinct from protein kinase C induces CD3 gamma-subunit phosphorylation without a concomitant down-regulation in CD3 antigen expression.
Topics: Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Ethers; Humans; Ionomycin; Ionophores; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes | 1989 |
Requirement and role of arachidonic acid in the differentiation of pre-adipose cells.
Topics: Adipose Tissue; Animals; Arachidonic Acid; Arachidonic Acids; Cell Differentiation; Cell Line; Cyclic AMP; Cyclic GMP; Ethers; Inositol; Ionomycin; Mice; Mice, Inbred C57BL; Mitosis; Phorbol 12,13-Dibutyrate; Phospholipids; Rats; Tetradecanoylphorbol Acetate | 1989 |
Diacylglycerol, but not inositol 1,4,5-trisphosphate, accounts for platelet-derived growth factor-stimulated proliferation of BALB 3T3 cells.
Topics: Animals; Cell Division; Cell Line; Diglycerides; Ethers; Glycerides; In Vitro Techniques; Inositol Phosphates; Ionomycin; Mice; Microinjections; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phosphatidylinositols; Platelet-Derived Growth Factor; Sugar Phosphates | 1989 |
Contrasting effects of inflammatory stimuli on neutrophil and monocyte adherence to endothelial cells.
Topics: Animals; Cattle; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydrogen Peroxide; Immune Adherence Reaction; Ionomycin; Monocytes; Neutrophils; Phorbol 12,13-Dibutyrate; Phorbols; Protein Kinase C; Second Messenger Systems; Superoxides | 1989 |
Endothelin stimulates diacylglycerol accumulation and activates protein kinase C in cultured vascular smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Cells, Cultured; Diglycerides; Endothelins; Endothelium, Vascular; Enzyme Activation; Ethers; Glycerides; Ionomycin; Kinetics; Molecular Weight; Muscle, Smooth, Vascular; Peptides; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1989 |
Increases in intracellular Ca2+ regulate the binding of [3H]phorbol 12,13-dibutyrate to intact 1321N1 astrocytoma cells.
Topics: Astrocytoma; Binding Sites; Bradykinin; Calcium; Carbachol; Cell Membrane; Cytosol; Diglycerides; Ethers; Histamine; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Kinetics; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; Tumor Cells, Cultured | 1989 |
Phorbol ester and calcium ionophore are sufficient to promote cell replication in cultures of quiescent human B lymphocytes.
Topics: B-Lymphocytes; Cell Division; Cells, Cultured; Ethers; Humans; Ionomycin; Ionophores; Leukocyte Count; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Tetradecanoylphorbol Acetate | 1989 |
Induction of tumoricidal activity and alterations of growth by interleukin-2 and manipulation of protein kinase C and cytosolic calcium in childhood acute lymphocytic leukemia cells.
Topics: Calcium; Child; Child, Preschool; Cytotoxicity, Immunologic; Ethers; Female; Humans; Infant; Interleukin-2; Ionomycin; Male; Phorbol 12,13-Dibutyrate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase C; Receptors, Interleukin-2; Recombinant Proteins | 1989 |
Selective effects of cholera toxin on the activation of mouse B cells by different polyclonal activators.
Topics: Animals; B-Lymphocytes; Cholera Toxin; Cyclic AMP; DNA; Ethers; GTP-Binding Proteins; Immunologic Capping; Ionomycin; Lipopolysaccharides; Lymphocyte Activation; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Receptors, Antigen, B-Cell; Virulence Factors, Bordetella | 1987 |
Role of phosphoinositide-derived second messengers in mediating anti-IgM-induced growth arrest of WEHI-231 B lymphoma cells.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Calcium; Cell Line; Dose-Response Relationship, Immunologic; Ethers; Growth Inhibitors; Immunoglobulin M; Ionomycin; Kinetics; Leukocyte Count; Lipopolysaccharides; Lymphocyte Activation; Lymphoma; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols | 1988 |
Interleukin 4 and soluble CD23 as progression factors for human B lymphocytes: analysis of their interactions with agonists of the phosphoinositide "dual pathway" of signalling.
Topics: Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Cell Differentiation; Ethers; Humans; In Vitro Techniques; Interleukin-4; Interleukins; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Receptors, Fc; Receptors, IgE; Solubility | 1988 |
Synergism between diacylglycerols and calcium ionophore in the induction of human B cell proliferation mimics the inositol lipid polyphosphate breakdown signals induced by crosslinking surface immunoglobulin.
Topics: B-Lymphocytes; Binding, Competitive; Cell Division; Diglycerides; Drug Synergism; Enzyme Activation; Ethers; Glycerides; Humans; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protein Kinase C; Protein Kinases; Receptors, Antigen, B-Cell; Staphylococcus aureus | 1985 |
Correlative studies on the effect of carbachol on myo-inositol trisphosphate accumulation, myosin light chain phosphorylation and contraction in sphincter smooth muscle of rabbit iris.
Topics: Animals; Atropine; Calcium; Carbachol; Ethers; Female; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Iris; Male; Membranes; Muscle Contraction; Muscle, Smooth; Myosins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphorylation; Rabbits; Sugar Phosphates; Temperature; Time Factors | 1986 |
Possible involvement of protein kinase C and calcium ion in growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts.
Topics: Animals; Calcimycin; Calcium; Cell Line; Diglycerides; Enzyme Activation; Ethers; Fibroblast Growth Factors; Fibroblasts; Gene Expression Regulation; Ionomycin; Mice; Oncogenes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Platelet-Derived Growth Factor; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
The human T3 gamma chain is phosphorylated at serine 126 in response to T lymphocyte activation.
Topics: Amino Acid Sequence; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Enzyme Activation; Ethers; Humans; Ionomycin; Lymphocyte Activation; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphoserine; Phytohemagglutinins; Protein Kinase C; Serine; T-Lymphocytes; Trypsin | 1987 |
Requirements for the simultaneous presence of phorbol esters and calcium ionophores in the expression of human T lymphocyte proliferation-related genes.
Topics: Cell Division; Drug Synergism; Ethers; Gene Expression Regulation; Humans; Interleukin-2; Ionomycin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Receptors, Immunologic; Receptors, Interleukin-2; RNA, Messenger; Stimulation, Chemical; T-Lymphocytes; Time Factors | 1987 |
Comparison of phorbol ester/calcium ionophore and phytohemagglutinin-induced signaling in human T lymphocytes. Demonstration of interleukin 2-independent transferrin receptor gene expression.
Topics: Cells, Cultured; Cycloheximide; Drug Synergism; Ethers; Gene Expression Regulation; Immunologic Techniques; Interleukin-2; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Phorbol Esters; Receptors, Immunologic; Receptors, Interleukin-2; Receptors, Transferrin; RNA, Messenger; T-Lymphocytes; Time Factors; Transferrin | 1988 |
Human neutrophil protein kinase C: calcium-induced changes in the solubility of the enzyme do not always correlate with enzymatic activity.
Topics: Algorithms; Benzofurans; Caenorhabditis elegans Proteins; Calcium; Carrier Proteins; Ethers; Fura-2; Humans; Ionomycin; Neutrophils; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Drug; Solubility | 1988 |
Cyclosporin A inhibits initiation but not progression of human T cell proliferation triggered by phorbol esters and calcium ionophores.
Topics: Cyclosporins; Drug Combinations; Ethers; Growth Inhibitors; Humans; Interleukin-2; Ionomycin; Ionophores; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes | 1988 |
Coordination and reversibility of signals for proliferative activation and interleukin-2 mRNA production in resting human T lymphocytes by phorbol ester and calcium ionophore.
Topics: Blotting, Northern; Calcium; Cells, Cultured; Ethers; Humans; Interleukin-2; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Phosphoproteins; RNA, Messenger; T-Lymphocytes | 1988 |
Induction of competence and progression signals in human T lymphocytes by phorbol esters and calcium ionophores.
Topics: Calcium; Cell Division; DNA Replication; Enzyme Activation; Ethers; Gene Expression Regulation; Humans; Interleukin-2; Ionomycin; Phorbol 12,13-Dibutyrate; Protein Kinase C; T-Lymphocytes | 1988 |
Mitogenic stimulation of human B lymphocytes via the inositol phospholipid 'dual pathway' of signalling requires persistent activation of both second messenger arms.
Topics: B-Lymphocytes; Ethers; Humans; Ionomycin; Ionophores; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Receptors, Antigen, B-Cell | 1988 |
Down regulation of protein kinase C in neuronal cells: effects on neurotransmitter release.
Topics: Animals; Cells, Cultured; Ethers; Ionomycin; Neurons; Nitrendipine; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Sympathetic Nervous System; Tetradecanoylphorbol Acetate | 1987 |
Synergistic interaction between interleukin 4 and anti-Bp50 (CDw40) revealed in a novel B cell restimulation assay.
Topics: Antibodies, Monoclonal; Antigens, Differentiation; B-Lymphocytes; DNA; Ethers; Humans; Interleukin-4; Interleukins; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate | 1987 |
Phorbol ester-induced protein secretion in rat parotid gland. Relationship to the role of inositol lipid breakdown and protein kinase C activation in stimulus-secretion coupling.
Topics: Animals; Calcium; Carcinogens; Egtazic Acid; Ethers; In Vitro Techniques; Inositol; Ionomycin; Kinetics; Male; Methacholine Chloride; Methacholine Compounds; Parotid Gland; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Proteins; Rats; Tritium | 1984 |
Secretagogue-induced formation of inositol phosphates in rat exocrine pancreas. Implications for a messenger role for inositol trisphosphate.
Topics: Animals; Carbachol; Ceruletide; Ethers; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Sugar Phosphates | 1984 |
Control of cell cycle entry and progression in mitogen-stimulated human B lymphocytes.
Topics: Antigens, CD; Antigens, CD20; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Cells, Cultured; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cyclins; HLA-DR Antigens; Humans; Immunosuppressive Agents; Ionomycin; Lymphocyte Activation; Mitogens; Palatine Tonsil; Phorbol 12,13-Dibutyrate; Phosphorylation; Proliferating Cell Nuclear Antigen; Protein Serine-Threonine Kinases; Retinoblastoma Protein | 1995 |
The role of bcl-XL in CD40-mediated rescue from anti-mu-induced apoptosis in WEHI-231 B lymphoma cells.
Topics: Animals; Antibodies, Anti-Idiotypic; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Apoptosis; bcl-X Protein; CD40 Antigens; CD40 Ligand; Gene Expression Regulation; Humans; Ionomycin; Lymphoma, B-Cell; Membrane Glycoproteins; Mice; Phorbol 12,13-Dibutyrate; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Terpenes; Thapsigargin; Transfection; Tumor Cells, Cultured | 1995 |
Role of inositol trisphosphate-sensitive calcium stores in the regulation of adrenocorticotropin secretion by perifused rat anterior pituitary cells.
Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Calcium; Corticotropin-Releasing Hormone; Cyclic AMP; Inositol 1,4,5-Trisphosphate; Ionomycin; Male; Perfusion; Phorbol 12,13-Dibutyrate; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Terpenes; Thapsigargin | 1995 |
Vaccination with IL-2-secreting tumor cells stimulates the generation of IL-2-responsive T cells and prevents the development of unresponsiveness.
Topics: Animals; Cytotoxicity, Immunologic; Fibrosarcoma; Genetic Vectors; Graft Rejection; H-2 Antigens; Immune Tolerance; Interleukin-2; Ionomycin; Killer Cells, Lymphokine-Activated; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Moloney murine leukemia virus; Neoplasm Transplantation; Phorbol 12,13-Dibutyrate; T-Lymphocyte Subsets; Transfection; Tumor Cells, Cultured; Vaccination | 1994 |
Activation of protein kinase C by the capsaicin analogue resiniferatoxin in sensory neurones.
Topics: Animals; Capsaicin; Cell Membrane; Cytosol; Diterpenes; Enzyme Activation; Ganglia, Spinal; Ionomycin; Male; Neurons; Neurotoxins; Phorbol 12,13-Dibutyrate; Potassium Chloride; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tritium | 1995 |
Ionomycin and PDBU increase MDCK monolayer permeability independently of myosin light chain phosphorylation.
Topics: Animals; Cell Line; Chemical Phenomena; Chemistry; Cyclic AMP; Dogs; Ionomycin; Kidney; Kinetics; Mathematics; Myosins; Permeability; Phorbol 12,13-Dibutyrate; Phosphorylation | 1995 |
The effect of tyrosine kinase inhibition on phorbol 12,13-dibutyrate- and ionomycin-induced LH and GH release.
Topics: Animals; Cinnamates; Growth Hormone; In Vitro Techniques; Ionomycin; Kinetics; Luteinizing Hormone; Phorbol 12,13-Dibutyrate; Pituitary Gland, Anterior; Protein-Tyrosine Kinases; Rats | 1995 |
Chloride channels in myocytes from rabbit colon are regulated by a pertussis toxin-sensitive G protein.
Topics: Animals; Bucladesine; Calcimycin; Cell Adhesion; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Colon; Cytosol; Diglycerides; Electric Conductivity; Electrophysiology; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Ion Channels; Ionomycin; Male; Meglumine; Membrane Potentials; Membrane Proteins; Muscle, Smooth; NAD; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Rabbits; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Tetraethylammonium; Tetraethylammonium Compounds; Virulence Factors, Bordetella | 1993 |
Effect of tyrosine kinase inhibitors on luteinizing hormone-releasing hormone (LHRH)-induced gonadotropin release from the anterior pituitary.
Topics: Animals; Cinnamates; Female; Follicle Stimulating Hormone; Genistein; Gonadotropin-Releasing Hormone; In Vitro Techniques; Ionomycin; Isoflavones; Luteinizing Hormone; Phenols; Phorbol 12,13-Dibutyrate; Pituitary Gland, Anterior; Proestrus; Protein-Tyrosine Kinases; Rats; Stilbenes | 1995 |
Multiple intracellular signallings are involved in thyrotropin-releasing hormone (TRH)-induced c-fos and jun B mRNA levels in clonal prolactin cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Clone Cells; Colforsin; Cyclic AMP; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Ionomycin; Neoplasm Proteins; Nuclear Proteins; Phorbol 12,13-Dibutyrate; Pituitary Gland, Anterior; Pituitary Neoplasms; Prolactin; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1995 |
Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of intracellular Ca2+ in the histamine H1 receptor-stimulated phosphorylation of Ser8, Ser19, Ser31, and Ser40.
Topics: Adrenal Medulla; Animals; Caffeine; Calcium; Cattle; Colforsin; Ionomycin; Peptide Mapping; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphoserine; Receptors, Histamine H1; Receptors, Nicotinic; Signal Transduction; Tyrosine 3-Monooxygenase | 1995 |
Stimulation and release of interleukin-1 from peritoneal macrophages of the mouse.
Topics: Animals; Calcimycin; In Vitro Techniques; Interleukin-1; Ionomycin; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred Strains; Neuropeptides; Phorbol 12,13-Dibutyrate; Tumor Necrosis Factor-alpha | 1994 |
Phorbol ester-, but not ligand-mediated activation of protein kinase C increases angiotensin binding to rat intestinal epithelial (RIE-1) cells.
Topics: Angiotensin II; Animals; Cell Line; Enzyme Activation; Epithelial Cells; Intestinal Mucosa; Ionomycin; Ligands; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Receptors, Angiotensin; Tetradecanoylphorbol Acetate; Up-Regulation | 1994 |
Anti-IgM and anti-IgG modulate c-fos RNA levels differently in human B lymphocytes.
Topics: Antibodies, Anti-Idiotypic; B-Lymphocytes; Blotting, Northern; Cell Line; Gene Expression Regulation; Genes, fos; Humans; Immunoglobulin G; Immunoglobulin M; Ionomycin; Nucleic Acid Hybridization; Phorbol 12,13-Dibutyrate; RNA, Messenger; Signal Transduction | 1994 |
Regulation of B-cell immune responses: predominant role of interleukin-4 in triggering cell proliferation and Ig production in competent B cells.
Topics: Antibodies, Anti-Idiotypic; Antibody Formation; B-Lymphocyte Subsets; Blotting, Northern; Child; Flow Cytometry; Humans; Immunoglobulin E; Immunoglobulin M; Interleukin-2; Interleukin-4; Ionomycin; Lymphocyte Activation; Palatine Tonsil; Phorbol 12,13-Dibutyrate; Receptors, Interleukin-2; Receptors, Interleukin-4; Receptors, Mitogen; T-Lymphocytes | 1994 |
Mechanism of desensitization of the cloned vasopressin V1a receptor expressed in Xenopus oocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine Vasopressin; Calcium; Cloning, Molecular; Cyclic AMP; Enzyme Activation; Ionomycin; Oocytes; Phenylephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Adrenergic, beta; Receptors, Vasopressin; Signal Transduction; Xenopus | 1994 |
Differential involvement of phospholipase A2 in phorbol ester-induced luteinizing hormone and growth hormone release from rat anterior pituitary tissue.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminobenzoates; Animals; Arachidonic Acid; Aristolochic Acids; Chlorobenzoates; Cinnamates; Cyclohexanones; Cycloheximide; Enzyme Activation; Female; Growth Hormone; Indoles; Ionomycin; Isoquinolines; Luteinizing Hormone; Melitten; ortho-Aminobenzoates; Phenanthrenes; Phenothiazines; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Piperazines; Pituitary Gland, Anterior; Proestrus; Protein Kinase C; Quinacrine; Rats; Rats, Wistar; Signal Transduction; Staurosporine | 1993 |
Activation of ion transport by combined effects of ionomycin, forskolin and phorbol ester on cultured HT-29cl.19A human colonocytes.
Topics: Biological Transport; Calcium; Carbachol; Chloride Channels; Colforsin; Colonic Neoplasms; Cyclic AMP; Drug Synergism; Electric Conductivity; Humans; Ionomycin; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C; Tumor Cells, Cultured | 1993 |
Effect of protein kinase-C depletion on inositol trisphosphate-mediated and cyclic adenosine 3',5'-monophosphate-dependent protein kinase-mediated adrenocorticotropin secretion.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Cyclic AMP; Cycloheximide; Diglycerides; Inositol 1,4,5-Trisphosphate; Ionomycin; Male; Perfusion; Phorbol 12,13-Dibutyrate; Pituitary Gland, Anterior; Potassium Chloride; Protein Kinase C; Protein Kinases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1993 |
Oestradiol-17 beta modulates the actions of pharmacologically distinct forms of protein kinase C in rat anterior pituitary cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cytosol; Diglycerides; Enzyme Activation; Estradiol; Female; Growth Hormone; Ionomycin; Isoenzymes; Isoquinolines; Luteinizing Hormone; Ovariectomy; Phorbol 12,13-Dibutyrate; Piperazines; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar | 1993 |
Phorbol dibutyrate and ionomycin improve murine effector cell cytotoxicity.
Topics: Animals; Cell Division; Cytotoxicity, Immunologic; Female; Immunotherapy, Adoptive; Ionomycin; Killer Cells, Lymphokine-Activated; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Phorbol 12,13-Dibutyrate | 1993 |
Regulation of T cell reactivities by intestinal mucosa.
Topics: Animals; CD3 Complex; Cells, Cultured; Concanavalin A; Erythrocytes; Humans; Immunoglobulin A; Interleukin-2; Intestinal Mucosa; Ionomycin; Lymphocyte Activation; Mitogens; Phorbol 12,13-Dibutyrate; Reactive Oxygen Species; Sheep; T-Lymphocyte Subsets; Tissue Extracts | 1995 |
Bradykinin stimulates phospholipase D in PC12 cells by a mechanism which is independent of increases in intracellular Ca2+.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Carbachol; Enzyme Inhibitors; Ethanol; Ionomycin; Ionophores; Neurons; PC12 Cells; Phorbol 12,13-Dibutyrate; Phospholipase D; Rats; Stimulation, Chemical; Terpenes; Thapsigargin | 1995 |
Arachidonic acid inhibits hCG-stimulated progesterone production by corpora lutea of primates: potential mechanism of action.
Topics: Animals; Arachidonic Acids; Calcium; Chorionic Gonadotropin; Corpus Luteum; Enzyme Activation; Female; Hydrolysis; Ionomycin; Macaca mulatta; Phorbol 12,13-Dibutyrate; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositol Phosphates; Phosphoric Diester Hydrolases; Progesterone; Protein Kinase C; Radioimmunoassay; Signal Transduction | 1995 |
Inactivated bovine herpesvirus 1 induces apoptotic cell death of mitogen-stimulated bovine peripheral blood mononuclear cells.
Topics: Animals; Apoptosis; Cattle; Cells, Cultured; DNA; Herpesvirus 1, Bovine; Ionomycin; Leukocytes, Mononuclear; Phorbol 12,13-Dibutyrate; Viral Proteins | 1996 |
Mechanism of bile salt-induced mucin secretion by cultured dog gallbladder epithelial cells.
Topics: Acetylglucosamine; Animals; Bile Acids and Salts; Calcimycin; Cells, Cultured; Cyclic AMP; Dinoprostone; Dogs; Edetic Acid; Enzyme Activation; Epithelium; Gallbladder; Ionomycin; Kinetics; Mucins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Second Messenger Systems; Taurochenodeoxycholic Acid; Taurocholic Acid; Tetradecanoylphorbol Acetate; Tritium | 1996 |
Human neutrophils secrete vascular endothelial growth factor.
Topics: Adult; Blotting, Western; Cells, Cultured; Endothelial Growth Factors; Female; Humans; Immunohistochemistry; Ionomycin; Ionophores; Lymphokines; Male; Middle Aged; Mouth Mucosa; Neutrophils; Phorbol 12,13-Dibutyrate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Zymosan | 1997 |
Assessment of the mechanism by which prolactin stimulates progesterone production by early corpora lutea of pigs.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carcinogens; Cells, Cultured; Corpus Luteum; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Female; Ionomycin; Ionophores; Lipoproteins, LDL; Luteal Phase; Phorbol 12,13-Dibutyrate; Progesterone; Prolactin; Protein Kinase C; Staurosporine; Stimulation, Chemical; Swine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1998 |
Functional expression of the Na/K pump is controlled via a cyclosporin A-sensitive signalling pathway in activated human lymphocytes.
Topics: Cyclosporine; DNA; Humans; Immunosuppressive Agents; In Vitro Techniques; Interleukin-2; Ion Transport; Ionomycin; Lymphocyte Activation; Lymphocytes; Ouabain; Phorbol 12,13-Dibutyrate; Phytohemagglutinins; Rubidium; Signal Transduction; Sodium-Potassium-Exchanging ATPase | 1999 |
Protein kinase C-delta is a target of B-cell antigen receptor signaling.
Topics: Animals; B-Lymphocytes; Biological Transport; Enzyme Activation; Estrenes; Humans; Ionomycin; Isoenzymes; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Phorbol 12,13-Dibutyrate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Processing, Post-Translational; Pyrrolidinones; Receptors, Antigen, B-Cell; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1999 |
Activation via multiple signaling pathways induces down-regulation of platelet-activating factor receptors on human B lymphocytes.
Topics: Antibodies, Anti-Idiotypic; B-Lymphocytes; Calcium; Cell Line, Transformed; Down-Regulation; Humans; Immunoglobulin M; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Antigen, B-Cell; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction | 2000 |
Regulation of conjunctival goblet cell secretion by Ca(2+)and protein kinase C.
Topics: Animals; Blotting, Western; Calcium; Chelating Agents; Conjunctiva; Glycoproteins; Goblet Cells; Ionomycin; Ionophores; Male; Microscopy, Fluorescence; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2000 |
Neuropeptide Y inhibits the protein kinase C-stimulated Cl(-) secretion in the human colonic cell line HT29cl.19A cell line via multiple sites.
Topics: Calcium; Chlorides; Colforsin; Colonic Neoplasms; Cyclic AMP; Electric Conductivity; HT29 Cells; Humans; Ionomycin; Membrane Potentials; Neuropeptide Y; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C | 2001 |
[Comparative study of the functional expression of the Na/K-pump in human lymphocytes, activated by phytohemagglutinin, phorbol ester, ionomycin, and interleukin-2].
Topics: Cell Division; Cyclosporine; Humans; Interleukin-2; Ionomycin; Lymphocytes; Phorbol 12,13-Dibutyrate; Phytohemagglutinins; Sodium-Potassium-Exchanging ATPase | 2001 |
Increased susceptibility of peripheral blood mononuclear cells to equine herpes virus type 1 infection upon mitogen stimulation: a role of the cell cycle and of cell-to-cell transmission of the virus.
Topics: Animals; Antigens, Viral; Cell Aggregation; Cell Cycle; Flow Cytometry; Herpesviridae Infections; Herpesvirus 1, Equid; Horse Diseases; Horses; Ionomycin; Ionophores; Leukocytes, Mononuclear; Lymphocyte Activation; Mitogens; Phorbol 12,13-Dibutyrate; Virus Replication | 2002 |
Prolactin signaling in porcine adrenocortical cells: involvement of protein kinases.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Androstenedione; Animals; Diglycerides; Enzyme Activators; Enzyme Inhibitors; Female; Genistein; Hydrocortisone; Ionomycin; Phorbol 12,13-Dibutyrate; Prolactin; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Sphingosine; Swine; Tetradecanoylphorbol Acetate | 2002 |
Regulation of parathyroid hormone-stimulated phospholipase D in UMR-106 cells by calcium, MAP kinase, and small G proteins.
Topics: Animals; Calcium; Cell Line, Tumor; Gene Expression Regulation; Humans; Ionomycin; Mitogen-Activated Protein Kinases; Monomeric GTP-Binding Proteins; Parathyroid Hormone; Phorbol 12,13-Dibutyrate; Phospholipase D; Protein Isoforms; Rats; rhoA GTP-Binding Protein | 2003 |
Receptor-operated Ca2+ influx and its association with the Src family in secretagogue-stimulated pancreatic acini.
Topics: Amylases; Animals; Calcium; Cattle; Cholecystokinin; Enzyme Inhibitors; Fibroblast Growth Factors; Genes, src; Genistein; Humans; Ionomycin; Male; Pancreas; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, G-Protein-Coupled; Receptors, Ghrelin; Recombinant Proteins; Sodium Fluoride; Tyrosine | 2004 |
Protein kinase C beta is dispensable for TCR-signaling.
Topics: Animals; CD28 Antigens; Cell Division; Genes, Reporter; Humans; Interleukin-2; Ionomycin; Ionophores; Isoenzymes; Jurkat Cells; Luciferases; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Knockout; Muromonab-CD3; Phorbol 12,13-Dibutyrate; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C-theta; Receptors, Antigen, T-Cell; Recombinant Fusion Proteins; Signal Transduction; T-Lymphocytes; Transfection | 2004 |
Mechanisms of M(1) muscarinic receptor-mediated up-regulation of neuronal nitric oxide synthase in N1E-115 neuroblastoma cells.
Topics: Analysis of Variance; Animals; Atropine; Blotting, Western; Carbachol; Cell Line, Tumor; Chelating Agents; Cholinergic Agonists; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Ionomycin; Ionophores; Mice; Muscarinic Antagonists; Nerve Tissue Proteins; Neuroblastoma; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phorbol 12,13-Dibutyrate; Phorbol Esters; Receptor, Muscarinic M1; Time Factors; Up-Regulation | 2005 |
Interleukin-2-dependent regulation of Na/K pump in human lymphocytes.
Topics: Cell Cycle; Humans; Interleukin-2; Ionomycin; Lymphocytes; Phorbol 12,13-Dibutyrate; Phytohemagglutinins; Rubidium; Sodium-Potassium-Exchanging ATPase | 2005 |
Zinc ions suppress mitogen-activated interleukin-2 production in Jurkat cells.
Topics: Cations, Divalent; Cell Survival; Concanavalin A; Gene Expression Regulation, Neoplastic; Humans; Interleukin-2; Ionomycin; Jurkat Cells; Mitogens; Phorbol 12,13-Dibutyrate; RNA, Messenger; Signal Transduction; Tacrolimus; Zinc | 2005 |
Effect of fluvastatin on apoptosis in human CD4+ T cells.
Topics: Antibodies; Apoptosis; bcl-2-Associated X Protein; Caspases; CD3 Complex; CD4-Positive T-Lymphocytes; Cells, Cultured; Cytochromes c; Down-Regulation; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; Ionomycin; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Proto-Oncogene Proteins c-bcl-2 | 2005 |
[Activation of transcriptional factors stat5 and stat3 during human T-lymphocyte proliferation induced by different mitogenic stimuli].
Topics: Carcinogens; Cell Proliferation; Humans; Interleukin-2; Ionomycin; Ionophores; Lymphocyte Activation; Mitogens; Phorbol 12,13-Dibutyrate; Phosphorylation; Phytohemagglutinins; Receptors, Interleukin-2; STAT3 Transcription Factor; STAT5 Transcription Factor; T-Lymphocytes | 2006 |
[Effect of extracellular-signal regulated kinase 1/2 specific repressor PD98059 on murine lymphocyte proliferation].
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Division; Cell Proliferation; Cells, Cultured; Concanavalin A; Flavonoids; Flow Cytometry; G2 Phase; Ionomycin; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Phorbol 12,13-Dibutyrate; S Phase | 2007 |
Protein kinase C signaling during T cell activation induces the endoplasmic reticulum stress response.
Topics: Animals; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Activation; Heat-Shock Proteins; Immune Tolerance; Interleukin-2; Ionomycin; Lymphocyte Activation; Male; Mice; Models, Biological; Molecular Chaperones; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase Inhibitors; Receptors, Antigen, T-Cell; Signal Transduction; Stress, Physiological; T-Lymphocytes; Thapsigargin; Up-Regulation | 2008 |
Ionomycin inhibits Jurkat T cell behaviors in the presence of phorbol-12,13-dibutyrate.
Topics: Apoptosis; Calcium; Calcium Ionophores; Caspase 3; Cell Proliferation; Dose-Response Relationship, Drug; Drug Combinations; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Leukemic; Humans; Hydrogen-Ion Concentration; Ionomycin; Jurkat Cells; Lymphocyte Activation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phorbol 12,13-Dibutyrate; S Phase; Signal Transduction; Transforming Growth Factor beta | 2014 |