phorbol 12,13-dibutyrate has been researched along with sphingosine in 57 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (19.30) | 18.7374 |
| 1990's | 40 (70.18) | 18.2507 |
| 2000's | 6 (10.53) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baron, R; Chakraborty, M; Nathanson, MH; Su, Y | 1 |
| Boekhoff, I; Breer, H | 1 |
| Faraci, FM; Heistad, DD; Murray, MA | 1 |
| Conti, F; Delfini, M; Miccheli, A; Piccolella, E; Ricciolini, R | 1 |
| Conti, F; Lagana, A; Miccheli, A; Piccolella, E; Ricciolini, R | 1 |
| Anwyl, R; McGuinness, N; Rowan, M | 1 |
| Fukuda, K; Kuno, T; Matsumura, F; Motoyoshi, H; Nagata, Y; Tanaka, S; Yamasaki, H | 1 |
| Baker, HJ; Shanker, G | 1 |
| Bell, RM; Hannun, YA; Merrill, AH | 1 |
| Suen, CS; Wilk, S | 1 |
| Huang, CL; Ives, HE; Lowe, JH | 1 |
| Jacobson, DP; O'Flaherty, JT; Redman, JF; Rossi, AG | 1 |
| Messing, RO; Savidge, B; Sneade, AB | 1 |
| Buckley, NE; Gibson, K; Spiegel, S; Zhang, H | 1 |
| Jamison, WC; Liotta, DC; Merrill, AH; Nimkar, S; Stevens, VL | 1 |
| Dorn, CC; Rice, WR; Singleton, FM | 1 |
| Ikebuchi, H; Saito, Y; Suzuki, K; Suzuki, S; Terao, T | 1 |
| Cline, HT; Constantine-Paton, M | 1 |
| Cobbold, PH; Cuthbertson, KS; Dixon, CJ; Sanchez-Bueno, A; Woods, NM | 1 |
| Aperia, A; Bertorello, A | 1 |
| Gillies, RJ; Hoyer, PB; Martinez, R; Sneider, JM | 1 |
| Badwey, JA; Horn, W; Karnovsky, MJ; Karnovsky, ML; Robinson, JM; Soberman, RJ | 1 |
| Canonico, PL; Catania, MV; Favit, A; Nicoletti, F | 1 |
| Bell, RM; Lambeth, JD; Merrill, AH; Olcott, MC; Wilson, E | 1 |
| Cheng, YC; Grill, SP; Li, JS; Nutter, LM; Tan, RS | 1 |
| Bell, RM; Greenberg, CS; Hannun, YA | 1 |
| Fernyhough, P; Hall, FL; Ishii, DN; Vulliet, PR | 1 |
| Bell, RM; Davis, RJ; Faucher, M; Gironès, N; Hannun, YA | 1 |
| Bell, RM; Hannun, YA; Loomis, CR; Merrill, AH | 1 |
| Bell, RM; Hannun, YA; Kinkade, JM; Merrill, AH; Sereni, AM; Stevens, VL | 1 |
| Areces, LB; Blumberg, PM; Kazanietz, MG | 1 |
| Meves, H; Schmitt, H | 1 |
| Rozengurt, E; Seufferlein, T | 2 |
| Fine, RL; Harrison, SD; Sachs, CW; Safa, AR | 1 |
| Terrian, DM; Ways, DK | 1 |
| Hundle, B; Messing, RO; Roivainen, R | 1 |
| Cho, Y; Ziboh, VA | 1 |
| Soares-da-Silva, P | 2 |
| Blobe, GC; Hannun, YA; Khan, WA; Richards, AL | 1 |
| Barnard, EA; Matsumoto, M | 1 |
| Fantus, IG; Nower, P; Schwartz, T; Torossian, K | 1 |
| Rossignol, B; Sergheraert, C; Zoukhri, D | 1 |
| Didion, SP; Mayhan, WG | 1 |
| Egashira, K; Fukumoto, Y; Ito, A; Kadokami, T; Shimokawa, H; Takayanagi, T; Takeshita, A | 1 |
| Carpenter, DO; Son, H | 1 |
| Antignac, P; Louisot, P; Rodriguez-Lafrasse, C; Rousson, R; Valla, S; Vanier, MT | 1 |
| Cui, SH; Ito, M; Tanabe, F | 1 |
| Hamada, K; Hirano, T; Nakamura, H; Oda, T; Shimizu, N; Utiyama, H | 2 |
| Dietrich, J; Geisler, C; Kastrup, J; Lauritsen, JP; Menné, C; Odum, N; Wegener, AM | 1 |
| Hannun, YA; Merrill, AH; Obeid, LM; Smith, ER | 1 |
| Ahmed, IS; Alderton, F; Darroch, P; McKie, A; Pyne, N; Pyne, S; Sambi, B | 1 |
| Haze, K; Kashiwagi, S; Kobayashi, S; Kuriyama, S; Kurokawa, T; Miwa, S; Mizukami, Y; Mogami, K; Nakao, F; Sato, M; Shirao, S; Suzuki, M; Todoroki-Ikeda, N | 1 |
| Ciereszko, RE; Dusza, L; Kaminska, B; Opalka, M | 1 |
| Carpenter, DO; Hussain, RJ | 1 |
57 other study(ies) available for phorbol 12,13-dibutyrate and sphingosine
| Article | Year |
|---|---|
Differential effects of the 3',5'-cyclic adenosine monophosphate and protein kinase C pathways on the response of isolated rat osteoclasts to calcitonin.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acid Phosphatase; Animals; Animals, Newborn; Bone Resorption; Calcitonin; Cell Line; Cells, Cultured; Cyclic AMP; In Vitro Techniques; Kinetics; Osteoclasts; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred Strains; Sphingosine; Stereoisomerism; Time Factors | 1992 |
Termination of second messenger signaling in olfaction.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Ethers, Cyclic; Feedback; Inositol 1,4,5-Trisphosphate; Nitriles; Okadaic Acid; Olfactory Mucosa; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; Second Messenger Systems; Signal Transduction; Smell; Sphingosine; Time Factors | 1992 |
Role of protein kinase C in constrictor responses of the rat basilar artery in vivo.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Basilar Artery; Dinoprost; Dose-Response Relationship, Drug; Enzyme Activation; Ergolines; Isoquinolines; Male; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Sphingosine; Vasoconstriction | 1992 |
Modulation of human lymphoblastoid B cell line by phorbol ester and sphingosine. A 31P-NMR study.
Topics: B-Lymphocytes; Cell Division; Cell Line, Transformed; Choline; Energy Metabolism; Enzyme Activation; Herpesvirus 4, Human; Humans; Magnetic Resonance Spectroscopy; Phorbol 12,13-Dibutyrate; Phospholipids; Phosphorylcholine; Protein Kinase C; Sphingosine | 1991 |
Modulation of the free sphingosine levels in Epstein Barr virus transformed human B lymphocytes by phorbol dibutyrate.
Topics: B-Lymphocytes; Cell Line, Transformed; Cell Membrane; Chromatography, High Pressure Liquid; Herpesvirus 4, Human; Humans; Phorbol 12,13-Dibutyrate; Sphingosine | 1991 |
Inhibition of an N-methyl-D-aspartate induced short-term potentiation in the rat hippocampal slice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Evoked Potentials; Hippocampus; In Vitro Techniques; Isoquinolines; N-Methylaspartate; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase Inhibitors; Rats; Sphingosine; Time Factors | 1991 |
Histamine H1-receptor-mediated keratan sulfate production in rabbit chondrocytes: involvement of protein kinase C.
Topics: Animals; Cartilage, Articular; Cells, Cultured; Chlorpheniramine; Keratan Sulfate; Kinetics; Methylhistamines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrilamine; Rabbits; Receptors, Histamine H1; Sphingosine | 1991 |
Phorbol ester receptors in cerebral cortex of cats with GM1 gangliosidosis.
Topics: Animals; Binding, Competitive; Caenorhabditis elegans Proteins; Carrier Proteins; Cats; Cerebral Cortex; G(M1) Ganglioside; Gangliosidoses; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Drug; Sphingosine | 1991 |
Use of sphingosine as inhibitor of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Death; Diglycerides; Enzyme Activation; Isoquinolines; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Sphingosine | 1991 |
Rapid inactivation and phosphorylation of pyroglutamyl peptidase II in Y-79 human retinoblastoma cells after exposure to phorbol ester.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Line; Epinephrine; Eye Neoplasms; Humans; Immune Sera; Immunoblotting; Isoquinolines; Kinetics; Molecular Weight; Phorbol 12,13-Dibutyrate; Phosphorylation; Piperazines; Protein Kinase C; Pyroglutamyl-Peptidase I; Retinoblastoma; Sphingosine; Tetradecanoylphorbol Acetate | 1990 |
Sphingosine differentially inhibits activation of the Na+/H+ exchanger by phorbol esters and growth factors.
Topics: Animals; Animals, Newborn; Biological Transport; Carrier Proteins; Cells, Cultured; Detergents; Diglycerides; Hydrogen-Ion Concentration; Kinetics; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Platelet-Derived Growth Factor; Rats; Sodium-Hydrogen Exchangers; Sphingosine; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Translocation of protein kinase C in human polymorphonuclear neutrophils. Regulation by cytosolic Ca2(+)-independent and Ca2(+)-dependent mechanisms.
Topics: Binding, Competitive; Caenorhabditis elegans Proteins; Calcimycin; Calcium; Carrier Proteins; Cell Membrane; Cytosol; Diglycerides; Humans; Ionomycin; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol 12,13-Dibutyrate; Phospholipids; Protein Kinase C; Receptors, Drug; Sphingosine | 1990 |
Protein kinase C participates in up-regulation of dihydropyridine-sensitive calcium channels by ethanol.
Topics: Adrenal Gland Neoplasms; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Cell Membrane; Ethanol; Isradipine; Kinetics; Oxadiazoles; Pheochromocytoma; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Rats; Sphingosine | 1990 |
Sphingosine stimulates cellular proliferation via a protein kinase C-independent pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Division; Cell Line; DNA; Down-Regulation; Drug Synergism; Fibroblasts; Growth Substances; Isoquinolines; Phorbol 12,13-Dibutyrate; Phosphorylation; Piperazines; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate | 1990 |
Characteristics of the growth inhibition and cytotoxicity of long-chain (sphingoid) bases for Chinese hamster ovary cells: evidence for an involvement of protein kinase C.
Topics: Animals; Cell Count; Cell Line; Cell Survival; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Female; L-Lactate Dehydrogenase; Ovary; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Sphingosine | 1990 |
P2-purinoceptor regulation of surfactant phosphatidylcholine secretion. Relative roles of calcium and protein kinase C.
Topics: Adenosine Triphosphate; Animals; Calcium; Diglycerides; Guanosine Triphosphate; Inositol Phosphates; Male; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Protein Kinase C; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sphingosine; Terbutaline | 1990 |
Human growth hormone-stimulated growth of human cultured lymphocytes (IM-9) and its inhibition by phorbol diesters through down-regulation of the hormone receptors. Possible involvement of phosphorylation of a 55,000 molecular weight protein associated wi
Topics: Alkaloids; Blood; Cell Division; Cell Line; Down-Regulation; Enzyme Activation; Growth Hormone; Humans; Kinetics; Lymphocytes; Molecular Weight; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphoproteins; Phosphorylation; Protein Kinase C; Receptors, Somatotropin; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
The differential influence of protein kinase inhibitors on retinal arbor morphology and eye-specific stripes in the frog retinotectal system.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Axons; Horseradish Peroxidase; Isoquinolines; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Piperazines; Polyvinyls; Protein Kinase Inhibitors; Rana pipiens; Retina; Retinal Ganglion Cells; Sphingosine; Superior Colliculi; Visual Pathways | 1990 |
Inhibitors of protein kinase C prolong the falling phase of each free-calcium transient in a hormone-stimulated hepatocyte.
Topics: Alkaloids; Animals; Arginine Vasopressin; Biological Clocks; Calcium; In Vitro Techniques; Liver; Male; Phenylephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred Strains; Sphingosine; Staurosporine; Stimulation, Chemical; Time Factors | 1990 |
Na+-K+-ATPase is an effector protein for protein kinase C in renal proximal tubule cells.
Topics: Animals; In Vitro Techniques; Kidney Tubules, Proximal; Kinetics; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred Strains; Reference Values; Sodium-Potassium-Exchanging ATPase; Sphingosine | 1989 |
Sphingosine inhibits phorbol 12-myristate 13-acetate-, but not serum-induced, activation of Na+/H+ exchange in mammalian cells.
Topics: Animals; Blood Physiological Phenomena; Carrier Proteins; Cell Line; Diglycerides; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Phorbol 12,13-Dibutyrate; Protein Kinase C; Sodium-Hydrogen Exchangers; Sphingosine; Tetradecanoylphorbol Acetate | 1989 |
Synergistic stimulation of neutrophils. Possible involvement of 5-hydroxy-6,8,11,14-eicosatetraenoate in superoxide release.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Cations, Divalent; Drug Synergism; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Isoquinolines; Neutrophils; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Sphingosine; Sulfonamides; Superoxides | 1988 |
Phorbol esters attenuate glutamate-stimulated inositol phospholipid hydrolysis in neuronal cultures.
Topics: Animals; Aspartic Acid; Carbachol; Cerebellum; Diglycerides; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; N-Methylaspartate; Neurons; Oxadiazoles; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Sphingosine; Tetradecanoylphorbol Acetate | 1988 |
Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst.
Topics: Arachidonic Acid; Arachidonic Acids; Calcium; Cell Membrane; Cell Survival; Cytochrome c Group; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Induction of virus enzymes by phorbol esters and n-butyrate in Epstein-Barr virus genome-carrying Raji cells.
Topics: Burkitt Lymphoma; Butyrates; Butyric Acid; Cells, Cultured; Deoxyribonucleases; DNA-Directed DNA Polymerase; DNA, Viral; Enzyme Induction; Genes, Viral; Herpesvirus 4, Human; Humans; Methylation; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1987 |
Sphingosine inhibition of agonist-dependent secretion and activation of human platelets implies that protein kinase C is a necessary and common event of the signal transduction pathways.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Diglycerides; Humans; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Platelet Activating Factor; Platelet Aggregation; Protein Kinase C; Sphingosine; Thrombin | 1987 |
Suppression of nerve growth factor-directed neurite outgrowth in PC12 cells by sphingosine, an inhibitor of protein kinase C.
Topics: Adrenal Gland Neoplasms; Animals; Cell Survival; Dose-Response Relationship, Drug; Nerve Growth Factors; Neurons; Pheochromocytoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; RNA, Messenger; Sphingosine; Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured | 1988 |
Regulation of the epidermal growth factor receptor phosphorylation state by sphingosine in A431 human epidermoid carcinoma cells.
Topics: Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; ErbB Receptors; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1988 |
Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.
Topics: Amines; Blood Platelets; Diglycerides; Humans; Micelles; Models, Biological; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylserines; Protein Kinase C; Sphingosine; Thrombin | 1986 |
Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases.
Topics: Acid Phosphatase; Binding, Competitive; Cell Adhesion; Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Sphingosine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1986 |
Close similarity of baculovirus-expressed n-chimaerin and protein kinase C alpha as phorbol ester receptors.
Topics: Amino Acid Sequence; Animals; Baculoviridae; Base Sequence; Caenorhabditis elegans Proteins; Carrier Proteins; Cells, Cultured; Chimerin 1; Isoenzymes; Molecular Sequence Data; Moths; Naphthalenes; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Phosphatidylserines; Phospholipids; Polycyclic Compounds; Protein Kinase C; Protein Kinase C-alpha; Receptors, Drug; Sphingosine | 1994 |
Modulation of neuronal calcium channels by arachidonic acid and related substances.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Calcium Channels; Hybrid Cells; Membrane Potentials; Mice; Myristic Acid; Myristic Acids; Neurons; Oleic Acid; Oleic Acids; Phorbol 12,13-Dibutyrate; Protein Kinase C; Quaternary Ammonium Compounds; Rats; Sphingosine; Trimethyl Ammonium Compounds | 1995 |
Sphingosylphosphorylcholine activation of mitogen-activated protein kinase in Swiss 3T3 cells requires protein kinase C and a pertussis toxin-sensitive G protein.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Antibodies; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cytochalasin D; DNA; DNA Replication; Egtazic Acid; Enzyme Activation; GTP-Binding Proteins; Intracellular Signaling Peptides and Proteins; Kinetics; Membrane Proteins; Mice; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Peptide Fragments; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphorylcholine; Protein Kinase C; Proteins; Sphingosine; Thymidine; Virulence Factors, Bordetella | 1995 |
Sphingosylphosphorylcholine rapidly induces tyrosine phosphorylation of p125FAK and paxillin, rearrangement of the actin cytoskeleton and focal contact assembly. Requirement of p21rho in the signaling pathway.
Topics: 3T3 Cells; Actins; ADP Ribose Transferases; Animals; Blotting, Western; Bombesin; Botulinum Toxins; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion Molecules; Cytoskeletal Proteins; Cytoskeleton; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Proteins; Indoles; Kinetics; Maleimides; Mice; Microinjections; Paxillin; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylcholine; Phosphotyrosine; Protein-Tyrosine Kinases; rho GTP-Binding Proteins; Signal Transduction; Sphingosine | 1995 |
Partial inhibition of multidrug resistance by safingol is independent of modulation of P-glycoprotein substrate activities and correlated with inhibition of protein kinase C.
Topics: Affinity Labels; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Breast Neoplasms; Cell Line; Cell Membrane; Cell Survival; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Enzyme Inhibitors; Female; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Phorbol 12,13-Dibutyrate; Protein Kinase C; Proteins; Rats; Recombinant Proteins; Sphingosine; Substrate Specificity; Tumor Cells, Cultured; Verapamil; Vinblastine | 1995 |
Persistent enhancement of sustained calcium-dependent glutamate release by phorbol esters: role of calmodulin-independent serine/threonine phosphorylation and actin disassembly.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Alkaloids; Animals; Barium; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cytochalasin D; Ethers, Cyclic; Glutamates; Guinea Pigs; Hippocampus; Isoquinolines; Male; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Phosphotransferases; Piperazines; Protein Kinase C; Serine; Sphingosine; Staurosporine; Subcellular Fractions; Sulfonamides; Synaptosomes; Threonine | 1995 |
Protein kinase C and adaptation to ethanol.
Topics: Acclimatization; Animals; Calcium; Calcium Channels; Cell Differentiation; Ethanol; Isoenzymes; Nerve Growth Factors; Neurites; Neurons; PC12 Cells; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; RNA, Messenger; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate | 1994 |
Expression of protein kinase C isozymes in guinea pig epidermis: selective inhibition of PKC-beta activity by 13-hydroxyoctadecadienoic acid-containing diacylglycerol.
Topics: Animals; Antibody Specificity; Blotting, Western; Cytosol; Diglycerides; Enzyme Activation; Epidermis; Guinea Pigs; Isoenzymes; Linoleic Acids; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase C beta; Radioligand Assay; Sphingosine | 1994 |
Renal tubular dopamine outward transfer during Na(+)-H+ exchange activation by alpha 1- and alpha 2-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Amiloride; Animals; Bucladesine; Colforsin; Dopamine; Hydrogen; In Vitro Techniques; Kidney Tubules; Levodopa; Phenylephrine; Phorbol 12,13-Dibutyrate; Quinoxalines; Rats; Sodium; Sphingosine | 1993 |
Identification, partial purification, and characterization of a novel phospholipid-dependent and fatty acid-activated protein kinase from human platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Blood Platelets; Blotting, Western; Calcium; Chromatography; Chromatography, Affinity; Chromatography, Ion Exchange; Diglycerides; Durapatite; Enzyme Activation; Humans; Isoquinolines; Kinetics; Oleic Acid; Oleic Acids; Phorbol 12,13-Dibutyrate; Phospholipids; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Sphingosine; Substrate Specificity | 1994 |
Effects of an activator and an inhibitor of protein kinase C on serotonin receptors induced by rat brain mRNA in Xenopus oocytes.
Topics: Aluminum Compounds; Animals; Brain; Chlorides; Electric Conductivity; Enzyme Activation; Fluorides; Kainic Acid; Oocytes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Receptors, Serotonin; RNA, Messenger; Serotonin; Sphingosine; Xenopus laevis | 1994 |
Phorbol esters inhibit insulin-induced receptor down-regulation in cultured human lymphocytes: association with diminished insulin receptor autophosphorylation.
Topics: Cell Line; Down-Regulation; Enzyme Activation; Humans; Insulin; Lymphocytes; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptor, Insulin; Sphingosine; Tetradecanoylphorbol Acetate | 1993 |
Phorbol ester-stimulated exocytosis in lacrimal gland: PKC might not be the sole effector.
Topics: Alkaloids; Animals; Benzophenanthridines; Bucladesine; Diglycerides; Exocytosis; In Vitro Techniques; Lacrimal Apparatus; Male; Phenanthridines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Trifluoperazine | 1993 |
Enhanced protein kinase C mediated inhibition of renal dopamine synthesis during high sodium intake.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Calcimycin; Dopamine; Enzyme Activation; Kidney; Kinetics; Levodopa; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Sodium, Dietary; Sphingosine | 1993 |
Activation of protein kinase C does not participate in disruption of the blood-brain barrier to albumin during acute hypertension.
Topics: Acute Disease; Animals; Blood Pressure; Blood-Brain Barrier; Capillary Permeability; Enzyme Activation; Enzyme Inhibitors; Hypertension; Male; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sphingosine | 1995 |
Coronary artery spasm does not depend on the intracellular calcium store but is substantially mediated by the protein kinase C-mediated pathway in a swine model with interleukin-1 beta in vivo.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium-Transporting ATPases; Coronary Vasospasm; Cytosol; Enzyme Activation; Histamine; Interleukin-1; Male; Muscle, Smooth, Vascular; Nifedipine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Ryanodine; Sarcoplasmic Reticulum; Serotonin; Sphingosine; Staurosporine; Swine; Terpenes; Thapsigargin | 1996 |
Protein kinase C activation is necessary but not sufficient for induction of long-term potentiation at the synapse of mossy fiber-CA3 in the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Enzyme Activation; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Nerve Fibers; Neural Pathways; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Sphingosine; Synapses | 1996 |
Modulation of protein kinase C by endogenous sphingosine: inhibition of phorbol dibutyrate binding in Niemann-Pick C fibroblasts.
Topics: Fibroblasts; Humans; Niemann-Pick Diseases; Phorbol 12,13-Dibutyrate; Protein Kinase C; Sphingosine; Tritium | 1997 |
Ceramide promotes calpain-mediated proteolysis of protein kinase C beta in murine polymorphonuclear leukocytes.
Topics: Animals; Calpain; Cysteine Proteinase Inhibitors; Down-Regulation; Isoenzymes; Leucine; Mice; Mice, Inbred C57BL; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Sphingosine | 1998 |
Involvement of Mac-1-mediated adherence and sphingosine 1-phosphate in survival of phorbol ester-treated U937 cells.
Topics: Apoptosis; CD18 Antigens; Cell Adhesion; Cell Survival; Humans; Integrins; Leukemia; Lysophospholipids; Macrophage-1 Antigen; Monocytes; Phorbol 12,13-Dibutyrate; Sphingosine; Tumor Cells, Cultured | 1998 |
Survival by Mac-1-mediated adherence and anoikis in phorbol ester-treated HL-60 cells.
Topics: Apoptosis; Cell Adhesion; HL-60 Cells; Humans; Indoles; Lysophospholipids; Nuclear Proteins; Phorbol 12,13-Dibutyrate; Phosphotransferases (Alcohol Group Acceptor); Sphingosine; Transcription Factors | 1998 |
Ceramide-induced TCR up-regulation.
Topics: Amino Acid Motifs; Down-Regulation; Enzyme Activation; Exocytosis; Humans; Jurkat Cells; Kinetics; Leucine; Leukocytes, Mononuclear; Lymphocyte Activation; Membrane Proteins; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Protein Kinase C; Protein Phosphatase 2; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; Sphingosine; T-Lymphocytes; Up-Regulation | 2000 |
Effects of sphingosine and other sphingolipids on protein kinase C.
Topics: 3T3 Cells; Animals; Cell Line; Cell Membrane; Isoenzymes; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Signal Transduction; Sphingolipids; Sphingosine; Tumor Cells, Cultured | 2000 |
G-protein-coupled receptor stimulation of the p42/p44 mitogen-activated protein kinase pathway is attenuated by lipid phosphate phosphatases 1, 1a, and 2 in human embryonic kidney 293 cells.
Topics: Cell Line; Cell Membrane; GTP-Binding Proteins; Humans; Isoenzymes; Kidney; Kinetics; Lysophospholipids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phorbol 12,13-Dibutyrate; Phosphatidate Phosphatase; Phosphatidic Acids; Phospholipase D; Receptors, Cell Surface; Recombinant Proteins; Sphingosine; Substrate Specificity; Tetradecanoylphorbol Acetate; Transfection; Virulence Factors, Bordetella | 2001 |
Sphingosylphosphorylcholine is a novel messenger for Rho-kinase-mediated Ca2+ sensitization in the bovine cerebral artery: unimportant role for protein kinase C.
Topics: Animals; Calcium Signaling; Cattle; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Cerebral Arteries; Culture Techniques; Enzyme Inhibitors; Escin; GTP-Binding Proteins; Intracellular Signaling Peptides and Proteins; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Phosphorylcholine; Protein Kinase C; Protein Serine-Threonine Kinases; rho-Associated Kinases; Sphingosine | 2002 |
Prolactin signaling in porcine adrenocortical cells: involvement of protein kinases.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Androstenedione; Animals; Diglycerides; Enzyme Activators; Enzyme Inhibitors; Female; Genistein; Hydrocortisone; Ionomycin; Phorbol 12,13-Dibutyrate; Prolactin; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Sphingosine; Swine; Tetradecanoylphorbol Acetate | 2002 |
The effects of protein kinase C activity on synaptic transmission in two areas of rat hippocampus.
Topics: Alkaloids; Animals; Benzophenanthridines; Diterpenes; Enzyme Activators; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Irritants; Isoenzymes; Male; Neural Pathways; Phenanthridines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Sphingosine; Synaptic Transmission | 2003 |