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phorbol 12,13-dibutyrate and phorbol-12,13-didecanoate

phorbol 12,13-dibutyrate has been researched along with phorbol-12,13-didecanoate in 62 studies

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199029 (46.77)18.7374
1990's29 (46.77)18.2507
2000's3 (4.84)29.6817
2010's1 (1.61)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Costa, J; Delang, L; Leyssen, P; Litaudon, M; Neyts, J; Nothias-Scaglia, LF; Pannecouque, C; Paolini, J; Renucci, F; Roussi, F1
Boscá, L; Genaro, AM; Hortelano, S1
Hashii, M; Higashida, H; Hoshi, N; Noda, M; Nozawa, Y; Shahidullah, M1
Obara, K; Usuki, T; Yabu, H1
Nakashima, T; Satoh, H; Tsuchida, K1
Byrne, JH; Critz, SD1
Alkhalaf, B; Gong, Y; Murphy, LC; Murphy, LJ1
Feldman, D; Krishnan, AV1
Fujiwara, N; Warashina, A1
Sekino, H; Suzuki-Nishimura, T; Uchida, MK1
Arner, EC; Pratta, MA1
Baker, HJ; Shanker, G1
Booth, RF; Gladwin, AM; Hassall, DG; Martin, JF1
Fredholm, B; Gullberg, M; Jondal, M; Kvanta, A; Nordstedt, C1
Ikebuchi, H; Saito, Y; Suzuki, K; Suzuki, S; Terao, T1
Cline, HT; Constantine-Paton, M1
Obie, JF; Putney, JW; Sugiya, H1
Galzin, AM; Langer, SZ; Ramdine, R1
De Graan, PN; Dekker, LV; Gispen, WH; Oestreicher, AB; Van der Voorn, L1
Fuller, SJ; Sugden, PH1
Akita, H; Fukuzaki, H; Go, M; Yokoyama, M1
Fredholm, BB; Kvanta, A; Nordstedt, C1
Madshus, IH; Olsnes, S; Sandvig, K1
Ginsberg, J; Murray, PG1
Kanno, Y; Sasaki, Y; Sastrodihardjo, S; Shiba, Y1
Ulenkate, HJ; Versteeg, DH1
Hamamori, Y; Nishimura, N; Takai, Y; Tsuda, T; Yamamoto, T1
Cavender, D; Haskard, D; Ziff, M1
Fujita, T; Fukase, M; Kinoshita, Y; Nakai, M1
Henderson, AH; Lewis, MJ1
Lytton, FD; Mitchell, MD1
Anderson, D; Dewdney, RS; Soper, CJ1
Andrade, R; Madison, DV; Malenka, RC; Nicoll, RA1
Bayard, F; Darbon, JM; Valette, A1
Chatterjee, M; Tejada, M1
Dale, MM; Obianime, AW1
McCulley, DE; Russell, JH; Taylor, AS1
Lefkowitz, RJ; Nambi, P; Sibley, DR1
Luikart, SD; Sackrison, JL1
Enomoto, T; Kanno, Y; Martel, N; Shiba, Y; Yamasaki, H1
Chen, BD; Hsu, S; Lin, HS1
Kuhn, LJ; Niedel, JE; Vandenbark, GR1
Burczak, JD; Fairley, JL; Moskal, JR; Sweeley, CC; Trosko, JE1
Elliott, MS; Katze, JR; Trewyn, RW1
Callaham, M; Huberman, E; Slaga, T; Solanki, V; Weeks, C1
de Prost, D; Hakim, J; Khechai, F; Ollivier, V; Ramani, M; Ternisien, C; Vu, T1
Mühl, H; Pfeilschifter, J1
Crevel, H; Marthan, R; Rossetti, M; Savineau, JP1
Hoy, K; Maccarone, P; Marley, PD; Thomson, KA1
Busija, D; Nam, M; Thore, CR1
Black, SC; Chi, L; Fagbemi, SO; Friedrichs, GS; Lucchesi, BR1
Bjur, RA; Khoyi, MA; Westfall, DP1
Akiguchi, I; Izumi, M; Nagataki, S1
Bond, J; Dawson, T; Eccles, N; Wynford-Thomas, D1
Tsien, RW; Yang, J1
Huber, G; Löffler, J1
Horowitz, B; Vogalis, F; Ward, M1
Bornefalk, E; Ljunggren, O; Ljunghall, S1
Harvey, RD; Middleton, LM1
Kuba, K; Liu, C; Shirasaki, T; Tanaka, S1
Chung, KH; Gye, MH; Shin, HJ; Yoo, BS1
Iijima, T; Satoh, E; Xu, F1

Other Studies

62 other study(ies) available for phorbol 12,13-dibutyrate and phorbol-12,13-didecanoate

ArticleYear
Antiviral Activity of Diterpene Esters on Chikungunya Virus and HIV Replication.
    Journal of natural products, 2015, Jun-26, Volume: 78, Issue:6

    Topics: Anti-HIV Agents; Antiviral Agents; Chikungunya virus; Diterpenes; DNA Replication; Esters; Euphorbiaceae; HIV Infections; HIV-1; HIV-2; Molecular Structure; Phorbol Esters; Tetradecanoylphorbol Acetate; Virus Replication

2015
Phorbol esters induce nitric oxide synthase activity in rat hepatocytes. Antagonism with the induction elicited by lipopolysaccharide.
    The Journal of biological chemistry, 1992, Dec-15, Volume: 267, Issue:35

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carcinogens; Cells, Cultured; Cyclic GMP; Diglycerides; Enzyme Induction; Kinetics; Lipopolysaccharides; Liver; Nitric Oxide Synthase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Tetradecanoylphorbol Acetate

1992
Ba2+ current oscillations modulated by cyclic AMP and phorbol esters in ras-transformed fibroblasts.
    Biochemical and biophysical research communications, 1992, Feb-14, Volume: 182, Issue:3

    Topics: 3T3 Cells; Animals; Barium; Bradykinin; Bucladesine; Cell Line, Transformed; Colforsin; Cyclic AMP; Evoked Potentials; Genes, ras; Kinetics; Kirsten murine sarcoma virus; Membrane Potentials; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Time Factors

1992
Calcium and potassium channel regulation by protein phosphorylation in smooth muscle cells of guinea pig taenia coli.
    Advances in experimental medicine and biology, 1992, Volume: 311

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Atropine; Calcium Channels; Carbachol; Colon; Guinea Pigs; In Vitro Techniques; Isoquinolines; Marine Toxins; Membrane Potentials; Models, Biological; Muscle, Smooth; Nifedipine; Oxazoles; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Piperazines; Potassium Channels; Protein Kinase C

1992
The responses to phorbol esters which stimulated protein kinase C in canine Purkinje fibers.
    General pharmacology, 1992, Volume: 23, Issue:5

    Topics: Action Potentials; Animals; Calcium; Carcinogens; Dogs; Homeostasis; Microelectrodes; Myocardial Contraction; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Purkinje Fibers; Tetradecanoylphorbol Acetate

1992
Modulation of IK,Ca by phorbol ester-mediated activation of PKC in pleural sensory neurons of Aplysia.
    Journal of neurophysiology, 1992, Volume: 68, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aplysia; Calcium; Dose-Response Relationship, Drug; Enzyme Activation; Ganglia; In Vitro Techniques; Isoquinolines; Kinetics; Membrane Potentials; Neurons, Afferent; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Piperazines; Potassium Channels; Protein Kinase C; Protein Kinase Inhibitors; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetraethylammonium Compounds

1992
Differential effects of phorbol esters on proliferation and calcyclin expression in human endometrial carcinoma cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1992, Volume: 3, Issue:11

    Topics: Adenocarcinoma; Alkaloids; Calcimycin; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Division; Cycloheximide; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; RNA, Messenger; RNA, Neoplasm; S100 Calcium Binding Protein A6; S100 Proteins; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Uterine Neoplasms

1992
Activation of protein kinase-C inhibits vitamin D receptor gene expression.
    Molecular endocrinology (Baltimore, Md.), 1991, Volume: 5, Issue:4

    Topics: Alkaloids; Animals; Blotting, Northern; Blotting, Southern; Calcimycin; Cell Division; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Down-Regulation; Fibroblast Growth Factor 2; Gene Expression Regulation, Enzymologic; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Calcitriol; Receptors, Steroid; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate

1991
Differential effects of protein kinase C activation on catecholamine secretions evoked by stimulations of various receptors in the rat adrenal medulla.
    Neuroscience letters, 1991, Aug-19, Volume: 129, Issue:2

    Topics: Adrenal Medulla; Animals; Bradykinin; Catecholamines; Diterpenes; Enzyme Activation; GTP-Binding Proteins; Histamine; In Vitro Techniques; Male; Muscarine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Terpenes

1991
The modulatory effects of phorbol esters on histamine release from mast cells induced by a polyethylenimine and a polyallylamine.
    General pharmacology, 1990, Volume: 21, Issue:4

    Topics: Animals; Histamine Release; In Vitro Techniques; Male; Mast Cells; Molecular Weight; Phorbol 12,13-Dibutyrate; Phorbol Esters; Polyamines; Polyethyleneimine; Polyethylenes; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1990
Modulation of interleukin-1-induced alterations in cartilage proteoglycan metabolism by activation of protein kinase C.
    Arthritis and rheumatism, 1991, Volume: 34, Issue:8

    Topics: Alkaloids; Animals; Carcinogens; Cartilage; Cattle; Dinoprostone; Diterpenes; Down-Regulation; Enzyme Activation; Interleukin-1; Organ Culture Techniques; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Proteoglycans; Staurosporine; Terpenes

1991
Phorbol ester receptors in cerebral cortex of cats with GM1 gangliosidosis.
    Neurochemical research, 1991, Volume: 16, Issue:1

    Topics: Animals; Binding, Competitive; Caenorhabditis elegans Proteins; Carrier Proteins; Cats; Cerebral Cortex; G(M1) Ganglioside; Gangliosidoses; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Drug; Sphingosine

1991
MAC-1 mediates adherence of human monocytes to endothelium via a protein kinase C dependent mechanism.
    Biochimica et biophysica acta, 1990, Apr-09, Volume: 1052, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Aorta; Cattle; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Humans; Kinetics; Macrophage-1 Antigen; Membrane Glycoproteins; Monocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Leukocyte-Adhesion

1990
Evidence that protein kinase C activation is essential for killing by IL-2-activated lymphocytes.
    Scandinavian journal of immunology, 1990, Volume: 31, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Chromium Radioisotopes; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Interleukin-2; Isoquinolines; Killer Cells, Lymphokine-Activated; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Piperazines; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Human growth hormone-stimulated growth of human cultured lymphocytes (IM-9) and its inhibition by phorbol diesters through down-regulation of the hormone receptors. Possible involvement of phosphorylation of a 55,000 molecular weight protein associated wi
    The Journal of biological chemistry, 1990, Jul-05, Volume: 265, Issue:19

    Topics: Alkaloids; Blood; Cell Division; Cell Line; Down-Regulation; Enzyme Activation; Growth Hormone; Humans; Kinetics; Lymphocytes; Molecular Weight; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphoproteins; Phosphorylation; Protein Kinase C; Receptors, Somatotropin; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate

1990
The differential influence of protein kinase inhibitors on retinal arbor morphology and eye-specific stripes in the frog retinotectal system.
    Neuron, 1990, Volume: 4, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Axons; Horseradish Peroxidase; Isoquinolines; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Piperazines; Polyvinyls; Protein Kinase Inhibitors; Rana pipiens; Retina; Retinal Ganglion Cells; Sphingosine; Superior Colliculi; Visual Pathways

1990
Two modes of regulation of the phospholipase C-linked substance-P receptor in rat parotid acinar cells.
    The Biochemical journal, 1988, Jul-15, Volume: 253, Issue:2

    Topics: Animals; Binding Sites; Calcium; Enzyme Activation; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Parotid Gland; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Tetradecanoylphorbol Acetate; Type C Phospholipases

1988
Phorbol-12,13-dibutyrate antagonizes while forskolin potentiates the presynaptic autoreceptor-mediated inhibition of [3H]-5-hydroxytryptamine release in rat hypothalamic slices.
    Synapse (New York, N.Y.), 1989, Volume: 3, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 5-Methoxytryptamine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Drug Interactions; Drug Synergism; Electric Stimulation; Evoked Potentials; Hypothalamus; Indoles; Male; Methiothepin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Polymyxin B; Rats; Rats, Inbred Strains; Serotonin

1989
Determination of changes in the phosphorylation state of the neuron-specific protein kinase C substrate B-50 (GAP43) by quantitative immunoprecipitation.
    Journal of neurochemistry, 1989, Volume: 52, Issue:1

    Topics: Animals; Cosyntropin; Electrophoresis, Polyacrylamide Gel; GAP-43 Protein; Immunosorbent Techniques; Male; Molecular Weight; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphoproteins; Phosphorylation; Polymyxin B; Protein Kinase C; Rats; Rats, Inbred Strains

1989
Protein synthesis in rat cardiac myocytes is stimulated at the level of translation by phorbol esters.
    FEBS letters, 1989, Apr-24, Volume: 247, Issue:2

    Topics: Animals; Dactinomycin; Kinetics; Male; Myocardium; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Biosynthesis; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Transcription, Genetic

1989
Phorbol ester modulates serotonin-stimulated phosphoinositide breakdown in cultured vascular smooth muscle cells.
    Biochemical and biophysical research communications, 1988, May-31, Volume: 153, Issue:1

    Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; GTP-Binding Proteins; Kinetics; Male; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Phosphorylation; Rabbits; Receptors, Serotonin; Serotonin; Tetradecanoylphorbol Acetate; Type C Phospholipases

1988
Agonist but not phorbol ester induced desensitization of human lymphocyte prostaglandin receptor is dependent on tubulin polymerization.
    Biochemical and biophysical research communications, 1988, Dec-30, Volume: 157, Issue:3

    Topics: Benzimidazoles; Binding, Competitive; Carcinogens; Colchicine; Cyclic AMP; Dinoprostone; Humans; Leukemia, T-Cell; Nocodazole; Phorbol 12,13-Dibutyrate; Phorbol Esters; Receptors, Prostaglandin; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured

1988
Tumor-promoting phorbol esters and vanadate alter the sensitivity of HeLa S3 cells to poliovirus type 1.
    Experimental cell research, 1985, Volume: 160, Issue:1

    Topics: Cell Membrane; HeLa Cells; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Poliovirus; Tetradecanoylphorbol Acetate; Vanadates; Vanadium

1985
Protein kinase C activators modulate differentiated thyroid function in vitro.
    FEBS letters, 1986, Oct-06, Volume: 206, Issue:2

    Topics: Animals; Bucladesine; Carcinogens; Enzyme Activation; Iodine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin

1986
Possible involvement of reorganization of actin filaments, induced by tumor-promoting phorbol esters, in changes in colony shape and enhancement of proliferation of cultured epithelial cells.
    Journal of cellular physiology, 1987, Volume: 132, Issue:1

    Topics: Actins; Animals; Cell Division; Cyclic AMP; Diterpenes; Dogs; Epithelial Cells; Epithelium; Kidney; Microscopy, Fluorescence; Phorbol 12,13-Dibutyrate; Phorbol Esters; Terpenes; Tetradecanoylphorbol Acetate; Time Factors

1987
Basal and electrically stimulated release of [3H]noradrenaline and [3H]dopamine from rat amygdala slices in vitro: effects of 4 beta-phorbol 12,13-dibutyrate, 4 alpha-phorbol 12,13-didecanoate and polymyxin B.
    Brain research, 1987, Jul-28, Volume: 416, Issue:2

    Topics: Amygdala; Animals; Dopamine; Electric Stimulation; In Vitro Techniques; Male; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Polymyxin B; Polymyxins; Rats; Rats, Inbred Strains

1987
Inhibition of DNA synthesis by protein kinase C-activating phorbol esters in NIH/3T3 cells.
    Journal of biochemistry, 1988, Volume: 104, Issue:1

    Topics: Animals; Cells, Cultured; DNA Replication; Enzyme Activation; Fibroblast Growth Factors; Insulin; Kinetics; Mice; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate

1988
Phorbol ester-stimulated T lymphocytes show enhanced adhesion to human endothelial cell monolayers.
    Journal of immunology (Baltimore, Md. : 1950), 1986, Sep-01, Volume: 137, Issue:5

    Topics: Cell Adhesion; Cells, Cultured; Endothelium; Fibroblasts; Gelatin; Humans; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate; Umbilical Veins

1986
Phorbol esters inhibit phosphate uptake in opossum kidney cells: a model of proximal renal tubular cells.
    Biochemical and biophysical research communications, 1987, May-29, Volume: 145, Issue:1

    Topics: Animals; Calcimycin; Cells, Cultured; Diglycerides; Kidney; Kidney Tubules, Proximal; Kinetics; Opossums; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphates

1987
A phorbol ester inhibits the release of endothelium-derived relaxing factor.
    European journal of pharmacology, 1987, Jun-04, Volume: 137, Issue:2-3

    Topics: Animals; Calcimycin; Carcinogens; Female; In Vitro Techniques; Male; Muscle Relaxation; Nitric Oxide; Nitroprusside; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rabbits; Vasodilator Agents

1987
Phorbol ester-induced stimulation of prostaglandin biosynthesis in human amnion cells.
    Biochimica et biophysica acta, 1988, Apr-15, Volume: 959, Issue:3

    Topics: Amnion; Dinoprostone; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Tetradecanoylphorbol Acetate

1988
Characterization of lymphocyte stimulation by phorbol related compounds.
    Human toxicology, 1988, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Animals; Humans; Irritants; Lymphocyte Activation; Male; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phytohemagglutinins; Skin Tests; Tetradecanoylphorbol Acetate

1988
Phorbol esters mimic some cholinergic actions in hippocampal pyramidal neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1986, Volume: 6, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Carbachol; Enzyme Activation; Evoked Potentials, Somatosensory; Hippocampus; Neurons; Parasympathomimetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Pyramidal Tracts; Rats; Receptors, Muscarinic; Tetraethylammonium Compounds; Tetrodotoxin

1986
Phorbol esters inhibit the proliferation of MCF-7 cells. Possible implication of protein kinase C.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Breast Neoplasms; Cell Division; Cell Line; Dose-Response Relationship, Drug; Female; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Tetradecanoylphorbol Acetate

1986
Phorbol ester-induced contraction in chemically skinned vascular smooth muscle.
    The American journal of physiology, 1986, Volume: 251, Issue:3 Pt 1

    Topics: Animals; Calcium; Carotid Arteries; Enzyme Activation; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Myosins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Potassium; Protein Kinase C; Skin Physiological Phenomena; Swine; Tetradecanoylphorbol Acetate

1986
4 beta-PDBu contracts parenchymal strip and synergizes with raised cytosolic calcium.
    European journal of pharmacology, 1987, Sep-02, Volume: 141, Issue:1

    Topics: Animals; Calcium; Cytosol; Dimethyl Sulfoxide; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate

1987
Antagonistic effects of phorbol esters on lymphocyte activation. Evidence that protein kinase C provides an early signal associated with lytic function.
    The Journal of biological chemistry, 1986, Sep-25, Volume: 261, Issue:27

    Topics: Animals; Cell Line; Kinetics; Lymphocyte Activation; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate

1986
Sensitization of frog erythrocyte adenylate cyclase system by tumor-promoting phorbol diesters.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:8

    Topics: Adenylyl Cyclases; Animals; Carcinogens; Erythrocyte Membrane; Erythrocytes; Fluorides; Isoproterenol; Kinetics; Manganese; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Rana pipiens; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1985
Effects of HL-60 cell membrane glycosaminoglycans on binding of differentiation-associated receptors.
    Experimental hematology, 1985, Volume: 13, Issue:7

    Topics: Cell Differentiation; Cell Membrane; Chondroitin Lyases; Chondroitin Sulfates; Glycosaminoglycans; Humans; Leukemia, Myeloid, Acute; N-Formylmethionine Leucyl-Phenylalanine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Trypsin

1985
Tumour promoter-mediated reversible inhibition of cell-cell communication (electrical coupling). Relationship with phorbol ester binding and de novo macromolecule synthesis.
    Experimental cell research, 1983, Volume: 146, Issue:2

    Topics: Binding Sites; Cell Communication; Cell Line; Cycloheximide; Dactinomycin; Diterpenes; Electrophysiology; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Biosynthesis; RNA; Terpenes; Tetradecanoylphorbol Acetate

1983
Tumor-promoting phorbol esters inhibit the binding of colony-stimulating factor (CSF-1) to murine peritoneal exudate macrophages.
    Journal of cellular physiology, 1983, Volume: 116, Issue:2

    Topics: Animals; Ascitic Fluid; Colony-Stimulating Factors; Dose-Response Relationship, Drug; Kinetics; Macrophages; Mice; Mice, Inbred C3H; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Receptors, Cell Surface; Receptors, Colony-Stimulating Factor; Temperature; Tetradecanoylphorbol Acetate

1983
Possible mechanism of phorbol diester-induced maturation of human promyelocytic leukemia cells.
    The Journal of clinical investigation, 1984, Volume: 73, Issue:2

    Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Differentiation; Cell Line; Enzyme Activation; Humans; Leukemia, Myeloid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Receptors, Drug; Tetradecanoylphorbol Acetate

1984
Phorbol ester-associated changes in ganglioside metabolism.
    Experimental cell research, 1983, Volume: 147, Issue:2

    Topics: Animals; Carcinogens; Cell Division; Cell Line; Contact Inhibition; Cricetinae; Gangliosides; Palmitic Acid; Palmitic Acids; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Sialic Acids; Sialyltransferases; Tetradecanoylphorbol Acetate

1983
Relationship between a tumor promoter-induced decrease in queuine modification of transfer RNA in normal human cells and the expression of an altered cell phenotype.
    Cancer research, 1984, Volume: 44, Issue:8

    Topics: Carcinogens; Cells, Cultured; Fibroblasts; Guanine; Humans; Infant, Newborn; Kinetics; Male; Phenotype; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; RNA, Transfer; Skin; Tritium

1984
Cell differentiation, alterations in polyamine levels, and specific binding of phorbol diesters in cultured human cells.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Binding Sites; Carcinogens; Cell Differentiation; Cell Line; Cell Membrane; Humans; Leukemia, Myeloid, Acute; Melanoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Polyamines; Tetradecanoylphorbol Acetate

1982
Endotoxin-induced tissue factor in human monocytes is dependent upon protein kinase C activation.
    Thrombosis and haemostasis, 1993, Nov-15, Volume: 70, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Endotoxins; Enzyme Activation; Gene Expression Regulation; Humans; Isoquinolines; Monocytes; Naphthalenes; Naphthol AS D Esterase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Polycyclic Compounds; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thromboplastin

1993
Possible role of protein kinase C-epsilon isoenzyme in inhibition of interleukin 1 beta induction of nitric oxide synthase in rat renal mesangial cells.
    The Biochemical journal, 1994, Oct-15, Volume: 303 ( Pt 2)

    Topics: Amino Acid Oxidoreductases; Animals; Blotting, Northern; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Induction; Glomerular Mesangium; Interleukin-1; Isoenzymes; NADH Dehydrogenase; Naphthalenes; Nitric Oxide Synthase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Polycyclic Compounds; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate

1994
Role of protein kinase C in nonsensitized and passively sensitized human isolated bronchial smooth muscle.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1

    Topics: Alkaloids; Allergens; Asthma; Bronchi; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Immunization, Passive; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Staurosporine; Time Factors; Verapamil

1995
Regulation of cyclic AMP levels by phorbol esters in bovine adrenal medullary cells.
    European journal of pharmacology, 1993, Jan-04, Volume: 244, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adrenal Medulla; Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Indoles; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Virulence Factors, Bordetella

1993
Phorbol ester-induced prostaglandin production in piglet cortical astroglia.
    The American journal of physiology, 1994, Volume: 267, Issue:1 Pt 2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Astrocytes; Cerebral Cortex; Dinoprost; Isoquinolines; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Prostaglandin Antagonists; Prostaglandins; Protein Kinase Inhibitors; Swine

1994
Phorbol ester-induced ventricular fibrillation in the Langendorff-perfused rabbit heart: antagonism by staurosporine and glibenclamide.
    Journal of molecular and cellular cardiology, 1993, Volume: 25, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Diglycerides; Glyburide; Guanidines; Isoquinolines; Perfusion; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pinacidil; Piperazines; Protein Kinase C; Rabbits; Staurosporine; Ventricular Fibrillation

1993
Time-dependent increase in Ca2+ influx in rabbit abdominal aorta: role of Na-Ca exchange.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: Animals; Aorta, Abdominal; Biological Transport, Active; Calcium; Carcinogens; Carrier Proteins; In Vitro Techniques; Kinetics; Male; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Ouabain; Phentolamine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rabbits; Sodium; Sodium-Calcium Exchanger; Time Factors

1993
Effects of phorbol ester on protein kinase C activity and effects of depletion of its activity on thyrotrophin, forskolin and 8'-bromoadenosine 3',5'-cyclic monophosphate-induced [3H]thymidine incorporation in rat FRTL-5 cells.
    The Journal of endocrinology, 1993, Volume: 138, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Colforsin; Cytosol; DNA; Dose-Response Relationship, Drug; Down-Regulation; Drug Administration Schedule; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Thymidine; Thyroid Gland; Thyrotropin

1993
Toxicity of phorbol esters for human epithelial cells expressing a mutant ras oncogene.
    Molecular carcinogenesis, 1993, Volume: 8, Issue:4

    Topics: Antineoplastic Agents; Bryostatins; Cell Division; Cell Line; DNA; Epithelial Cells; Epithelium; Gene Expression Regulation; Genes, ras; Humans; Lactones; Macrolides; Models, Biological; Mutation; Phorbol 12,13-Dibutyrate; Phorbol Esters; Proto-Oncogene Proteins p21(ras); Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thyroid Gland; Zinc

1993
Enhancement of N- and L-type calcium channel currents by protein kinase C in frog sympathetic neurons.
    Neuron, 1993, Volume: 10, Issue:2

    Topics: Alkaloids; Animals; Barium; Calcium Channels; Electric Conductivity; Ganglia, Sympathetic; GTP-Binding Proteins; Kinetics; Neurons; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rana catesbeiana; Staurosporine

1993
Modulation of beta-amyloid precursor protein secretion in differentiated and nondifferentiated cells.
    Biochemical and biophysical research communications, 1993, Aug-31, Volume: 195, Issue:1

    Topics: Amyloid beta-Protein Precursor; Animals; Bucladesine; Calcimycin; Carcinogens; Cell Differentiation; Cell Line; Culture Media; PC12 Cells; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate

1993
Suppression of two cloned smooth muscle-derived delayed rectifier potassium channels by cholinergic agonists and phorbol esters.
    Molecular pharmacology, 1995, Volume: 48, Issue:6

    Topics: Acetylcholine; Animals; Calcium; Cholinergic Agonists; Cloning, Molecular; DNA, Complementary; Dogs; Enzyme Activation; Female; GTP-Binding Proteins; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phorbol Esters; Potassium Channels; Protein Kinase C; Receptors, Muscarinic; Second Messenger Systems; Transfection; Xenopus laevis

1995
Bone resorption induced by A23187 is abolished by indomethacin: implications for second messenger utilised by parathyroid hormone.
    European journal of pharmacology, 1998, Mar-26, Volume: 345, Issue:3

    Topics: Animals; Animals, Newborn; Bone Resorption; Calcimycin; Calcium; Calcium Radioisotopes; Colforsin; Cyclooxygenase Inhibitors; Humans; Indomethacin; Ionophores; Mice; Parathyroid Hormone; Phorbol 12,13-Dibutyrate; Phorbol Esters; Recombinant Proteins; Second Messenger Systems

1998
PKC regulation of cardiac CFTR Cl- channel function in guinea pig ventricular myocytes.
    The American journal of physiology, 1998, Volume: 275, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Enzyme Activation; Female; Guinea Pigs; Heart; Heart Ventricles; Isoproterenol; Kinetics; Male; Membrane Potentials; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C

1998
Activity-dependent enhancement of miniature excitatory postsynaptic current amplitude and its modulation by protein kinase C in cultured rat sympathetic neurons.
    Neuroscience letters, 2000, Feb-11, Volume: 280, Issue:1

    Topics: Acetylcholine; Animals; Animals, Newborn; Calcium; Cells, Cultured; Egtazic Acid; Excitatory Postsynaptic Potentials; Kinetics; Neurons; Phorbol 12,13-Dibutyrate; Phorbol Esters; Potassium; Protein Kinase C; Rats; Rats, Wistar; Superior Cervical Ganglion; Synapses

2000
Activity of protein kinase C modulates the apoptosis induced by polychlorinated biphenyls in human leukemic HL-60 cells.
    Toxicology letters, 2002, Sep-05, Volume: 135, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Chlorodiphenyl (54% Chlorine); Diglycerides; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Inhibitors; HL-60 Cells; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate

2002
Protein kinase C-mediated Ca2+ entry in HEK 293 cells transiently expressing human TRPV4.
    British journal of pharmacology, 2003, Volume: 140, Issue:2

    Topics: Calcium; Cation Transport Proteins; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Humans; Hypotonic Solutions; Indoles; Ion Channels; Maleimides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; TRPV Cation Channels

2003