Compounds > phorbol 12,13-dibutyrate
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phorbol 12,13-dibutyrate and indolactam v

phorbol 12,13-dibutyrate has been researched along with indolactam v in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's6 (50.00)18.2507
2000's5 (41.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Acs, P; Ahmad, S; Blumberg, PM; Bogi, K; Glazer, RI; Kozikowski, AP; Lewin, NE; Ma, D; Modarres, S; Wang, S; Yao, J1
Hayashi, H; Irie, K; Nakagawa, Y; Ohigashi, H; Wender, PA1
Blumberg, PM; Enyedy, IJ; Kung, JW; Lorenzo, PS; Pak, Y; Varady, J; Wang, S1
Harmody, D; Longley, RE1
Akerman, KE; Heikkilä, J1
Balapure, AK; Feuerstein, N; Lindsberg, ML; Mond, JJ1
Henke, R; Knipp, SC; Peiper, U; Thies, B1
Basu, A1
Hayashi, H; Irie, K; Nakagawa, Y; Nakamura, Y; Ohigashi, H1
Cantwell, AM; Long, W; Longo, LD; Miguel, C; Nanyonga, AT; Saito, T; Windemuth, RS; Zhang, L; Zhao, Y1
Irie, K; Masuda, A; Nakagawa, Y; Ohigashi, H; Shindo, M1
Basu, A; Huang, J; Mohanty, S1

Other Studies

12 other study(ies) available for phorbol 12,13-dibutyrate and indolactam v

ArticleYear
Modeling, chemistry, and biology of the benzolactam analogues of indolactam V (ILV). 2. Identification of the binding site of the benzolactams in the CRD2 activator-binding domain of PKCdelta and discovery of an ILV analogue of improved isozyme selectivit
    Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9

    Topics: Antineoplastic Agents; Binding Sites; Binding, Competitive; Breast Neoplasms; Cell Division; Crystallography, X-Ray; Enzyme Inhibitors; Female; Humans; Hydrogen Bonding; Indoles; Isoenzymes; Lactams; Lyngbya Toxins; Models, Molecular; Molecular Conformation; Molecular Structure; Mutagenesis, Site-Directed; Protein Kinase C; Tumor Cells, Cultured

1997
Synthesis and PKC isozyme surrogate binding of indothiolactam-V, a new thioamide analogue of tumor promoting indolactam-V.
    Bioorganic & medicinal chemistry letters, 2000, Sep-18, Volume: 10, Issue:18

    Topics: Binding, Competitive; Carcinogens; Enzyme Activation; Indoles; Isoenzymes; Lactams; Magnetic Resonance Spectroscopy; Peptide Fragments; Phorbol 12,13-Dibutyrate; Protein Binding; Protein Kinase C; Thioamides

2000
Structural basis of binding of high-affinity ligands to protein kinase C: prediction of the binding modes through a new molecular dynamics method and evaluation by site-directed mutagenesis.
    Journal of medicinal chemistry, 2001, May-24, Volume: 44, Issue:11

    Topics: Crystallography, X-Ray; Indoles; Isoenzymes; Lactams; Ligands; Models, Molecular; Monte Carlo Method; Mutagenesis, Site-Directed; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Binding; Protein Kinase C; Protein Kinase C-delta

2001
A rapid colorimetric microassay to detect agonists/antagonists of protein kinase C based on adherence of EL-4.IL-2 cells.
    The Journal of antibiotics, 1991, Volume: 44, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Carcinogens; Cell Adhesion; Colorimetry; Diterpenes; Dose-Response Relationship, Drug; Enzyme Activation; Indoles; Isoquinolines; Lactams; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Reproducibility of Results; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured

1991
(-)-Indolactam V activates protein kinase C and induces changes in muscarinic receptor functions in SH-SY5Y human neuroblastoma cells.
    Biochemical and biophysical research communications, 1989, Aug-15, Volume: 162, Issue:3

    Topics: Calcium; Cell Compartmentation; Cell Differentiation; Cell Membrane; Enzyme Activation; Humans; Indoles; Lactams; Neuroblastoma; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
PKC activity and protein phosphorylation in regulation of sIg mediated B cell activation.
    Scandinavian journal of immunology, 1995, Volume: 41, Issue:2

    Topics: Animals; B-Lymphocytes; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Indoles; Lactams; Lymphocyte Activation; Mice; Mice, Inbred DBA; Phorbol 12,13-Dibutyrate; Phosphoproteins; Protein Kinase C

1995
Activation of protein kinase C accelerates contraction kinetics of airway smooth muscle.
    Pflugers Archiv : European journal of physiology, 1996, Volume: 432, Issue:3 Suppl

    Topics: Animals; Electrophysiology; Enzyme Activation; In Vitro Techniques; Indoles; Kinetics; Lactams; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Rats; Rats, Wistar; Receptors, Muscarinic; Trachea; Verapamil; Vibration

1996
The involvement of novel protein kinase C isozymes in influencing sensitivity of breast cancer MCF-7 cells to tumor necrosis factor-alpha.
    Molecular pharmacology, 1998, Volume: 53, Issue:1

    Topics: Antineoplastic Agents; Breast Neoplasms; Bryostatins; Carcinogens; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Lactams; Lactones; Macrolides; Maleimides; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Tumor Necrosis Factor; Sensitivity and Specificity; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1998
Synthesis and biological activities of (-)-6-n-octyl-indolactam-V, a new potent analogue of the tumor promoter (-)-indolactam-V.
    Bioscience, biotechnology, and biochemistry, 1998, Volume: 62, Issue:8

    Topics: Antigens, Viral; Carcinogens; Chromatography, Gel; Chromatography, High Pressure Liquid; Indoles; Lactams; Magnetic Resonance Spectroscopy; Mass Spectrometry; Optical Rotation; Palladium; Phorbol 12,13-Dibutyrate; Protein Kinase C; Spectrophotometry, Ultraviolet; Streptomycetaceae; Superoxides; Surface Properties

1998
Dual role of PKC in modulating pharmacomechanical coupling in fetal and adult cerebral arteries.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:4

    Topics: Animals; Cell Membrane; Cerebral Arteries; Enzyme Inhibitors; Feedback; Fetus; Indoles; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Lactams; Naphthalenes; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Sheep; Signal Transduction; Staurosporine; Vasoconstriction

2000
Tumor promoter binding of the protein kinase C C1 homology domain peptides of RasGRPs, chimaerins, and Unc13s.
    Bioorganic & medicinal chemistry, 2004, Sep-01, Volume: 12, Issue:17

    Topics: Amino Acid Sequence; Binding Sites; Carcinogens; Chimerin Proteins; DNA-Binding Proteins; Glycogen Synthase; Guanine Nucleotide Exchange Factors; Humans; Indoles; Isoenzymes; Lactams; Ligands; Molecular Sequence Data; Nerve Tissue Proteins; Peptide Fragments; Phorbol 12,13-Dibutyrate; Protein Kinase C

2004
Enhancement of cisplatin sensitivity of cisplatin-resistant human cervical carcinoma cells by bryostatin 1.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Sep-15, Volume: 11, Issue:18

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Bryostatins; Caspase 3; Caspases; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Female; HeLa Cells; Humans; Indoles; Lactams; Macrolides; Phorbol 12,13-Dibutyrate; Poly(ADP-ribose) Polymerases; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; RNA Interference; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Transfection; Uterine Cervical Neoplasms

2005