phorbol 12,13-dibutyrate has been researched along with guanosine 5'-o-(3-thiotriphosphate) in 38 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (5.26) | 18.7374 |
1990's | 29 (76.32) | 18.2507 |
2000's | 7 (18.42) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Kucera, GL; Rittenhouse, SE | 1 |
Andrade, R; Malenka, RC; Nicoll, RA | 1 |
Brown, DA; Marrion, NV; Smart, TG | 1 |
Gandy, S; Greengard, P; Xu, H | 1 |
Gong, MC; Kinter, MT; Somlyo, AP; Somlyo, AV | 1 |
Fujita, A; Hata, F; Nakajima, H; Nishio, H; Takeuchi, T | 1 |
Mayer, E; Sun, XP; Supplisson, S | 1 |
Kitamura, K; Kuriyama, H; Oike, M | 1 |
Itoh, T; Suzuki, A; Watanabe, Y | 1 |
Akhtar, RA; Choi, MW | 1 |
Green, MA; Li, PP; Sibony, D; Warsh, JJ | 1 |
Challiss, RA; Nahorski, SR; Stuart, JA; Willars, GB | 1 |
Gong, MC; Jensen, PE; Somlyo, AP; Somlyo, AV | 1 |
Budd, DC; McLaughlin, M; Nicholls, DG | 1 |
Helliwell, RM; Large, WA | 1 |
Deth, RC; Jinsi-Parimoo, A | 1 |
Fujihara, H; Gong, MC; Somlyo, AP; Somlyo, AV; Walker, LA | 1 |
Hattori, Y; Kanno, M; Kitabatake, A; Kohya, T; Sasaki, M; Tomita, F | 1 |
Hirono, M; Suzuki, N; Takagi, H; Yoshioka, T | 1 |
Ahn, SC; Kim, KW; Kim, SJ; So, I | 1 |
Dobashi, K; Horie, T; Iizuka, K; Mori, M; Nakazawa, T; Suzuki, H; Yoshii, A | 1 |
Imanaga, I; Inoue, M; Sakamoto, Y; Yano, A | 1 |
Fujita, R; Kawasaki, S; Kimura, S; Matsumoto, M; Sasaki, K; Sato, M; Takashima, K | 1 |
Boquet, P; Fujihara, H; Gong, MC; Lemichez, E; Somlyo, AP; Somlyo, AV; Walker, LA | 1 |
Grillner, S; Parker, D; Svensson, E | 1 |
Fu, X; Gong, MC; Jia, T; Somlyo, AP; Somlyo, AV | 1 |
Bukusoglu, C; Strichartz, GR; Xiong, Z | 1 |
Hattori, Y; Kanno, M; Kitabatake, A; Kohya, T; Moriishi, K; Oguma, K; Sasaki, M; Tomita, F | 1 |
Conn, PJ; Macek, TA; Schaffhauser, H | 1 |
Dobashi, K; Iizuka, K; Ishizuka, T; Mori, M; Nakazawa, T; Samizo, K; Tsukagoshi, H; Yoshii, A | 1 |
Fujishima, M; Hirano, K; Ibayashi, S; Kanaide, H; Nakamura, K; Nishimura, J | 1 |
Brautigan, DL; Eto, M; Everett, A; Kitazawa, T; Woodsome, TP | 1 |
Cho, H; Earm, YE; Ho, WK; Youm, JB | 1 |
Eto, Y; Kandabashi, T; Kunihiro, I; Matsumoto, Y; Miyata, K; Morishige, K; Nakayama, K; Obara, K; Shimokawa, H; Takahashi, S; Takeshita, A | 1 |
Dobashi, K; Endou, K; Iizuka, K; Ishizuka, T; Mori, M; Nakazawa, T; Tsukagoshi, H; Yoshii, A | 1 |
Arner, A; Bonnevier, J | 1 |
Silverman, M; Speight, P | 1 |
38 other study(ies) available for phorbol 12,13-dibutyrate and guanosine 5'-o-(3-thiotriphosphate)
Article | Year |
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Role of protein methylation in agonist-induced signal transduction in human platelets.
Topics: Acetylcysteine; Blood Platelets; Blood Proteins; Calcium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Immune Sera; Methylation; Methyltransferases; Phorbol 12,13-Dibutyrate; Platelet Activation; Platelet Aggregation; rap GTP-Binding Proteins; Signal Transduction; Thrombin | 1992 |
Human platelets form 3-phosphorylated phosphoinositides in response to alpha-thrombin, U46619, or GTP gamma S.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Calcimycin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Inositol Phosphates; Kinetics; Phorbol 12,13-Dibutyrate; Phosphates; Phosphatidylinositol Phosphates; Phosphatidylinositols; Prostaglandin Endoperoxides, Synthetic; Thionucleotides; Thrombin | 1990 |
A G protein couples serotonin and GABAB receptors to the same channels in hippocampus.
Topics: Animals; Baclofen; Calcium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Hippocampus; Ion Channels; Phorbol 12,13-Dibutyrate; Phorbol Esters; Potassium; Rats; Receptors, GABA-A; Receptors, Serotonin; Serotonin; Spiperone; Thionucleotides | 1986 |
On the transduction mechanism for muscarine-induced inhibition of M-current in cultured rat sympathetic neurones.
Topics: Animals; Cells, Cultured; Fetus; Ganglia, Sympathetic; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Inositol 1,4,5-Trisphosphate; Muscarine; Neural Inhibition; Neurons; Phorbol 12,13-Dibutyrate; Potassium Channels; Rats; Rats, Inbred Strains; Thionucleotides | 1989 |
Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein.
Topics: Aluminum Compounds; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Biological Transport, Active; Cell-Free System; Enzyme Activation; Fluorides; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Humans; PC12 Cells; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats | 1995 |
Arachidonic acid and diacylglycerol release associated with inhibition of myosin light chain dephosphorylation in rabbit smooth muscle.
Topics: Animals; Arachidonic Acid; Calcium Channel Agonists; Diglycerides; Gas Chromatography-Mass Spectrometry; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth, Vascular; Myosin Light Chains; Phenylephrine; Phorbol 12,13-Dibutyrate; Phosphorylation; Rabbits; Type C Phospholipases; Vasoconstrictor Agents | 1995 |
Involvement of heterotrimeric GTP-binding protein and rho protein, but not protein kinase C, in agonist-induced Ca2+ sensitization of skinned muscle of guinea pig vas deferens.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Aluminum Compounds; Animals; Botulinum Toxins; Calcium; Escin; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Peptides; Phorbol 12,13-Dibutyrate; Protein Kinase C; rho GTP-Binding Proteins; Vas Deferens | 1995 |
Chloride channels in myocytes from rabbit colon are regulated by a pertussis toxin-sensitive G protein.
Topics: Animals; Bucladesine; Calcimycin; Cell Adhesion; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Colon; Cytosol; Diglycerides; Electric Conductivity; Electrophysiology; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Ion Channels; Ionomycin; Male; Meglumine; Membrane Potentials; Membrane Proteins; Muscle, Smooth; NAD; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Rabbits; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Tetraethylammonium; Tetraethylammonium Compounds; Virulence Factors, Bordetella | 1993 |
Protein kinase C activates the non-selective cation channel in the rabbit portal vein.
Topics: Alkaloids; Animals; Chlorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Ion Channels; Male; Muscle, Smooth, Vascular; Nicardipine; Niflumic Acid; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Portal Vein; Protein Kinase C; Rabbits; Staurosporine; Virulence Factors, Bordetella | 1993 |
Effect of a peptide inhibitor of protein kinase C on G-protein-mediated increase in myofilament Ca(2+)-sensitivity in rabbit arterial skinned muscle.
Topics: Actin Cytoskeleton; Animals; Binding Sites; Calcium; Escin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Myosins; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Rabbits | 1994 |
Activation of phospholipase D by guanosine 5'[gamma-thio]triphosphate and AlF4- in bovine corneal epithelial cells.
Topics: Aluminum Compounds; Animals; Cattle; Cells, Cultured; Cornea; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Epithelium; Fluorides; Glycerophospholipids; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Microsomes; Myristic Acid; Myristic Acids; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phospholipase D | 1994 |
Lithium modulation of phosphoinositide signaling system in rat cortex: selective effect on phorbol ester binding.
Topics: Animals; Caenorhabditis elegans Proteins; Calcium Channels; Carbachol; Carrier Proteins; Cell Membrane; Cerebral Cortex; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Lithium Chloride; Male; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, Drug; Signal Transduction; Sodium Fluoride | 1993 |
Contrasting effects of phorbol ester and agonist-mediated activation of protein kinase C on phosphoinositide and Ca2+ signalling in a human neuroblastoma.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Carbachol; Cell Line; CHO Cells; Cricetinae; Cytosol; Enzyme Activation; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Lithium; N-Methylscopolamine; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Receptor, Muscarinic M3; Receptors, Muscarinic; Recombinant Proteins; Scopolamine Derivatives; Signal Transduction; Terpenes; Thapsigargin; Transfection; Tumor Cells, Cultured | 1996 |
Separate upstream and convergent downstream pathways of G-protein- and phorbol ester-mediated Ca2+ sensitization of myosin light chain phosphorylation in smooth muscle.
Topics: Animals; Calcium; Carbachol; Cell Membrane; Cytosol; Femoral Artery; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ileum; In Vitro Techniques; Isoenzymes; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Myosin Light Chains; Phorbol 12,13-Dibutyrate; Phosphorylation; Portal Vein; Protein Kinase C; Rabbits; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1996 |
The target of PKC induced suppression of adenosine inhibition of glutamate release from synaptosomes is downstream of the A1 receptor and G-protein coupling.
Topics: Adenosine; Animals; Glutamic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isoenzymes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase C-delta; Rats; Receptors, Purinergic P1; Synaptosomes | 1996 |
Alpha 1-adrenoceptor activation of a non-selective cation current in rabbit portal vein by 1,2-diacyl-sn-glycerol.
Topics: Alkaloids; Animals; Benzophenanthridines; Carcinogens; Cyclohexanones; Diglycerides; Enzyme Inhibitors; Estrenes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Inositol 1,4,5-Trisphosphate; Lipoprotein Lipase; Norepinephrine; Phenanthridines; Phorbol 12,13-Dibutyrate; Phosphodiesterase Inhibitors; Portal Vein; Pyrrolidinones; Rabbits; Receptors, Adrenergic, alpha-1; Thionucleotides; Type C Phospholipases | 1997 |
Reconstitution of alpha2D-adrenergic receptor coupling to phospholipase D in a PC12 cell lysate.
Topics: Animals; Cell-Free System; Cloning, Molecular; Enzyme Activation; Epinephrine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Models, Biological; Myristic Acid; Myristic Acids; PC12 Cells; Phorbol 12,13-Dibutyrate; Phospholipase D; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-2; Recombinant Proteins; Transfection | 1997 |
Down-regulation of G-protein-mediated Ca2+ sensitization in smooth muscle.
Topics: Aluminum Compounds; Animals; Antifungal Agents; Bacterial Toxins; Calcium; Detergents; Down-Regulation; Endothelins; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hemolysin Proteins; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myosin Light Chains; Phenylephrine; Phorbol 12,13-Dibutyrate; Phosphoric Monoester Hydrolases; Phosphorylation; Portal Vein; Precipitin Tests; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Pyrans; Rabbits; rhoA GTP-Binding Protein; Solubility; Spiro Compounds; Time Factors | 1997 |
Different regulation of myofilament Ca2+ sensitivity in beta-escin-skinned cardiac and vascular smooth muscles.
Topics: Actin Cytoskeleton; Animals; Calcium; Cardiotonic Agents; Drug Evaluation, Preclinical; Enzyme Activation; Escin; Guanosine 5'-O-(3-Thiotriphosphate); Heart Ventricles; Histological Techniques; Mesenteric Arteries; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyridazines; Rabbits | 1997 |
Facilitation of Ca2+ action potential frequency by a small G protein Rab3A in rat pituitary GH3 cells.
Topics: Action Potentials; Animals; Calcium; Enzyme Inhibitors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Patch-Clamp Techniques; Peptide Fragments; Peptides; Phorbol 12,13-Dibutyrate; Phorbols; Pituitary Gland; Protein Kinase C; rab3 GTP-Binding Proteins; rab5 GTP-Binding Proteins; ras Proteins; Rats; Thionucleotides; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1997 |
Inhibitory effect of phorbol 12,13 dibutyrate on carbachol-activated nonselective cationic current in guinea-pig gastric myocytes.
Topics: Animals; Carbachol; Cations; Electric Conductivity; Gastric Mucosa; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ion Channels; Muscarinic Agonists; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Stomach | 1997 |
Receptor-dependent G protein-mediated Ca2+ sensitization in canine airway smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aluminum; Animals; Bacterial Toxins; Calcium; Calcium-Binding Proteins; Calponins; Carbachol; Cell Membrane Permeability; Dogs; Endothelin-1; Escin; Female; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hemolysin Proteins; Histamine; Isometric Contraction; Male; Microfilament Proteins; Muscle, Smooth; Peptide Fragments; Phorbol 12,13-Dibutyrate; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Muscarinic; Serotonin; Thromboxane A2; Trachea | 1997 |
Cyanide suppression of inwardly rectifying K+ channels in guinea pig chromaffin cells involves dephosphorylation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Adrenal Medulla; Animals; Cells, Cultured; Chromaffin Cells; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Kinetics; Marine Toxins; Membrane Potentials; Oxazoles; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Potassium Channels; Potassium Channels, Inwardly Rectifying; Ribonucleotides; Sodium Cyanide; Uridine Triphosphate | 1997 |
Functional uncoupling between the receptor and G-protein as the result of PKC activation, observed in Aplysia neurons.
Topics: Acetylcholine; Animals; Aplysia; Dopamine; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Enzyme Activation; Enzyme Inhibitors; FMRFamide; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Neurons; Neuropeptides; Neurotransmitter Agents; Okadaic Acid; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Receptors, Cell Surface | 1997 |
Inhibition of RhoA translocation and calcium sensitization by in vivo ADP-ribosylation with the chimeric toxin DC3B.
Topics: Adenosine Diphosphate; ADP Ribose Transferases; Animals; Biological Transport; Botulinum Toxins; Calcium; Cell Membrane; Cytosol; Diphtheria Toxin; Endothelins; Guanine Nucleotide Dissociation Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Isometric Contraction; Muscle, Smooth, Vascular; Peptide Fragments; Phenylephrine; Phorbol 12,13-Dibutyrate; Portal Vein; Precipitin Tests; Protein Binding; Rabbits; Recombinant Fusion Proteins; rho-Specific Guanine Nucleotide Dissociation Inhibitors; rhoA GTP-Binding Protein; Sodium Dodecyl Sulfate | 1997 |
Substance P modulates sensory action potentials in the lamprey via a protein kinase C-mediated reduction of a 4-aminopyridine-sensitive potassium conductance.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Action Potentials; Adenylate Cyclase Toxin; Alkaloids; Animals; Benzophenanthridines; Cadmium Chloride; Electric Stimulation; Enzyme Inhibitors; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Lampreys; Male; Neurons; Notochord; Peptides; Pertussis Toxin; Phenanthridines; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C; Protein Kinases; Spinal Cord; Substance P; Tetraethylammonium; Thionucleotides; Virulence Factors, Bordetella; Wasp Venoms | 1997 |
The effects of the Rho-kinase inhibitor Y-27632 on arachidonic acid-, GTPgammaS-, and phorbol ester-induced Ca2+-sensitization of smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Arachidonic Acid; Calcium; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Models, Biological; Muscle Contraction; Muscle, Smooth, Vascular; Myosin Light Chains; Octoxynol; Permeability; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Serine-Threonine Kinases; Pulmonary Artery; Pyridines; Rabbits; rho-Associated Kinases; Type C Phospholipases | 1998 |
Local anesthetics inhibit the G protein-mediated modulation of K+ and Ca++ currents in anterior pituitary cells.
Topics: Anesthetics, Local; Animals; Calcium; Calcium Channels; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Lidocaine; Phorbol 12,13-Dibutyrate; Pituitary Gland, Anterior; Potassium Channels; Rats; Receptors, Thyrotropin-Releasing Hormone; Somatostatin; Thyrotropin-Releasing Hormone | 1999 |
Tyrosine phosphorylation as a convergent pathway of heterotrimeric G protein- and rho protein-mediated Ca2+ sensitization of smooth muscle of rabbit mesenteric artery.
Topics: Adenosine Diphosphate; ADP Ribose Transferases; Animals; Botulinum Toxins; Calcium; Carcinogens; Dimerization; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phenylephrine; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; rho GTP-Binding Proteins; Ribose; Staurosporine; Tyrosine; Tyrphostins; Vasoconstrictor Agents | 1998 |
Activation of PKC disrupts presynaptic inhibition by group II and group III metabotropic glutamate receptors and uncouples the receptor from GTP-binding proteins.
Topics: Adenosine; Animals; Dihydropyridines; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Phorbol 12,13-Dibutyrate; Phorbols; Propionates; Protein Kinase C; Receptor, Adenosine A3; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Synaptic Transmission | 1999 |
A major role for the rho-associated coiled coil forming protein kinase in G-protein-mediated Ca2+ sensitization through inhibition of myosin phosphatase in rabbit trachea.
Topics: Amides; Animals; Calcium; Enzyme Inhibitors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Myosin-Light-Chain Phosphatase; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; Trachea | 1999 |
Hydroxyfasudil, an active metabolite of fasudil hydrochloride, relaxes the rabbit basilar artery by disinhibition of myosin light chain phosphatase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Basilar Artery; Calcium; Endothelin-1; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Protein Kinase C; Rabbits; Vasodilator Agents | 2001 |
Expression of CPI-17 and myosin phosphatase correlates with Ca(2+) sensitivity of protein kinase C-induced contraction in rabbit smooth muscle.
Topics: Actins; Animals; Aorta; Calcium; Calcium-Binding Proteins; Calponins; Carcinogens; Femoral Artery; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immunohistochemistry; Male; Microfilament Proteins; Muscle Contraction; Muscle Proteins; Muscle, Smooth, Vascular; Myosin Light Chains; Myosin-Light-Chain Phosphatase; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Portal Vein; Protein Kinase C; Rabbits; Trachea; Urinary Bladder; Vas Deferens | 2001 |
Inhibition of acetylcholine-activated K(+) current by chelerythrine and bisindolylmaleimide I in atrial myocytes from mice.
Topics: Acetylcholine; Alkaloids; Animals; Atrial Function; Benzophenanthridines; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Heart Atria; Indoles; Maleimides; Membrane Potentials; Mice; Naphthalenes; Patch-Clamp Techniques; Phenanthridines; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C | 2001 |
Evidence for protein kinase C-mediated activation of Rho-kinase in a porcine model of coronary artery spasm.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Calcium; Capillary Permeability; Coronary Vasospasm; Coronary Vessels; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Monomeric GTP-Binding Proteins; Muscle Contraction; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Transport; rho-Associated Kinases; Swine | 2003 |
8-Bromo-cAMP decreases the Ca2+ sensitivity of airway smooth muscle contraction through a mechanism distinct from inhibition of Rho-kinase.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bronchi; Calcium; Carbachol; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Intracellular Signaling Peptides and Proteins; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Protein Serine-Threonine Kinases; Rabbits; rho-Associated Kinases; Trachea | 2004 |
Actions downstream of cyclic GMP/protein kinase G can reverse protein kinase C-mediated phosphorylation of CPI-17 and Ca²⁺ sensitization in smooth muscle.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amides; Animals; Bacterial Toxins; Blood Vessels; Calcium; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Escin; Female; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Intestine, Small; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Permeability; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases | 2004 |
Diacylglycerol-activated Hmunc13 serves as an effector of the GTPase Rab34.
Topics: Animals; Binding Sites; Cell Line; Diglycerides; Golgi Apparatus; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kidney; Mutation; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Protein Binding; Protein Structure, Tertiary; rab GTP-Binding Proteins; Recombinant Fusion Proteins; Two-Hybrid System Techniques | 2005 |