phorbol 12,13-dibutyrate has been researched along with colforsin in 169 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (15.38) | 18.7374 |
| 1990's | 111 (65.68) | 18.2507 |
| 2000's | 24 (14.20) | 29.6817 |
| 2010's | 8 (4.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Hashii, M; Higashida, H; Hoshi, N; Noda, M; Nozawa, Y; Shahidullah, M | 1 |
| Albert, DA; Rozengurt, E | 1 |
| Alton, EW; Geddes, DM; Smith, SN | 1 |
| Araki, T; Kato, H; Kogure, K | 2 |
| Araki, T; Kato, H; Kogure, K; Murase, K | 1 |
| Bockaert, J; Curry, K; Homburger, V; Manzoni, O; Prezeau, L; Sladeczek, F | 1 |
| Broad, S; Brooks, SF; Herget, T; Rozengurt, E | 1 |
| Fukuuchi, Y; Gomi, S; Mihara, B; Nagata, E; Nogawa, S; Nozaki, H; Shirai, T; Takashima, S; Tanaka, K | 3 |
| Bajnath, RB; de Jonge, HR; Groot, JA; van Hoeve, MH | 1 |
| Busija, DW; Chen, J | 1 |
| Alton, EW; Geddes, DM; Graham, A; Steel, DM | 1 |
| Auffredou, MT; Galanaud, P; Leca, G; Vazquez, A | 1 |
| Araki, T; Hara, H; Kato, H; Kogure, K; Onodera, H | 2 |
| Nahorski, SR; Wojcikiewicz, RJ | 1 |
| Ransjö, M | 1 |
| Magistretti, PJ; Sorg, O | 1 |
| Chiba, T; Fujita, T; Kadowaki, S; Morishita, T; Nakamura, A; Yamaguchi, A; Yamatani, T | 1 |
| Greenfield, LJ; Hackett, JT; Linden, J | 1 |
| Mehmet, H; Morris, C; Rozengurt, E | 1 |
| Malamed, S; Perez, FM; Scanes, CG | 1 |
| Bryant, SH; Conte-Camerino, D | 1 |
| Horsburgh, K; McCulloch, J | 2 |
| Araki, T; Hara, H; Kato, H; Kogure, K | 1 |
| Hösli, E; Hösli, L | 1 |
| Kamatchi, GL; Ticku, MK | 1 |
| Bryant, A; Farrant, J; Franz, A | 1 |
| De Costa, BR; Groen, BG; Herkenham, M; Lynn, AB; Richfield, EK | 1 |
| Bertrand, F; Capeau, J; Cherqui, G; Garcia, I; Hermelin, B; Paul, A; Picard, J | 1 |
| Donaldson, J; Hill, SJ; Kendall, DA | 1 |
| Gomi, S; Gotoh, F; Mihara, B; Takashima, S; Tanaka, K | 1 |
| Feuerstein, N; Francis, ML; Lindsberg, ML; Mond, JJ; Tung, L | 1 |
| Deckert, J; Jorgensen, MB | 1 |
| Aiyar, N; Crooke, ST; Nambi, P; Wu, HL | 1 |
| Edvinsson, L; Horsburgh, K; Jansen, I; McCulloch, J | 1 |
| Billestrup, N; Nielsen, JH; Petersen, ED | 1 |
| Bhave, SV; Malhotra, RK; Wakade, AR; Wakade, TD | 1 |
| Bastidas, JA; Orandle, MS; Yeo, CJ; Zinner, MJ | 1 |
| de Boland, AR; Norman, A | 1 |
| Giri, PR; Hoffman, PL; Rabe, CS; Tabakoff, B | 1 |
| Aiyar, N; Crooke, ST; Nambi, P | 1 |
| Burstein, DE; Lacal, JC; Pellicer, A; Thomson, TM; Trotta, RJ | 1 |
| McArdle, CA | 1 |
| Emoto, T; Hiraiwa, M; Kasai, K; Shimoda, S | 1 |
| Gross, RA; Macdonald, RL | 1 |
| Goto, Y; Sugamura, K; Takeshita, T | 1 |
| Bilan, PJ; Douen, AG; Klip, A; Ramlal, T; Skorecki, KL | 1 |
| Galzin, AM; Langer, SZ; Ramdine, R | 2 |
| Groome, JR; Watson, WH | 1 |
| Brown, BL; Dobson, PR; Quilliam, LA | 1 |
| Cabot, MC; Cao, HT; Welsh, CJ; Zhang, ZC | 1 |
| Nishimura, J; van Breemen, C | 1 |
| Malhotra, RK; Wakade, AR; Wakade, TD | 1 |
| Fredholm, BB; Jondal, M; Kvanta, A; Nordstedt, C | 1 |
| Holl, RW; Leong, DA; Thorner, MO | 1 |
| Dale, MM; Obianime, AW | 1 |
| Baraban, J; Worley, P; Zarbin, MA | 1 |
| Higgs, NB; Lees, M; Tonge, A; Turnberg, LA; Warhurst, G | 1 |
| Gott, AL; Gray, SM; James, AF; Leese, HJ | 1 |
| Haba, K; Hirakawa, S; Mizukawa, K; Ogawa, N; Tsushima, T | 1 |
| Cahill, AL; Perlman, RL; Wang, M | 1 |
| Browning, MD; Greengard, P; Haycock, JW | 1 |
| Fredholm, BB; Nordstedt, C | 1 |
| Collins, M; Murray, M; Rozengurt, E; Zachary, I | 1 |
| Schorderet-Slatkine, S; Urner, F | 2 |
| Gomi, S; Gotoh, F; Ishihara, N; Mihara, B; Takashima, S; Tanaka, K | 1 |
| Flaim, SF; Gleason, MM | 1 |
| Bajnath, RB; De Jonge, HR; Dekker, K; Groot, JA | 1 |
| Bertrand, PP; Galligan, JJ | 1 |
| Carter, DA | 3 |
| Bennett, JL; Blair, KL; Pax, RA | 1 |
| Eichberg, J; Rowe-Rendleman, CL | 1 |
| Arkhammar, P; Berggren, PO; Bertorello, AM; Efendić, S; Zaitsev, SV | 1 |
| Cobbold, PH; Dixon, CJ; Green, AK | 1 |
| Hoy, K; Maccarone, P; Marley, PD; Thomson, KA | 1 |
| Mayer, E; Sun, XP; Supplisson, S | 1 |
| Barnes, PJ; Haddad, EB; Mak, JC; Rousell, J | 1 |
| Boulla, G; Gourdji, D; Passegue, E; Richard, JL | 1 |
| Aharon, A; Kraiem, Z; Sadeh, O; Yosef, M | 1 |
| Hall, IP; Hill, SJ; McCreath, G | 1 |
| Austin, LM; Bunn, SJ; Dunkley, PR; Herd, LM; Sim, AT | 1 |
| Capogna, M; Gähwiler, BH; Thompson, SM | 1 |
| Araki, T; Kanai, Y; Kato, H; Kogure, K | 2 |
| Brunello, N; Perez, J; Racagni, G; Rovescalli, AC; Steardo, L; Vitali, S | 1 |
| Pimplikar, SW; Simons, K | 1 |
| Conte Camerino, D; De Luca, A; Pierno, S; Tricarico, D | 1 |
| Fukuuchi, Y; Gomi, S; Mihara, B; Takashima, S; Tanaka, K | 1 |
| Soares-da-Silva, P | 1 |
| Adam, LP; al-Hassani, MH; Gunst, SJ | 1 |
| Goldstein, JL; Layden, TJ; Rao, MC; Sahi, J | 1 |
| Awtrey, CS; Hecht, G; Madara, JL; Matthews, JB; Tally, KJ; Thompson, RS | 1 |
| Ichikawa, K; Ito, M; Itoh, H; Konishi, T; Nakano, T; Okubo, S; Shimomura, A | 1 |
| Barajas-López, C | 1 |
| Bajnath, RB; Bijman, J; De Jonge, HR; Groot, JA; Kansen, M | 1 |
| Bajnath, RB; De Jonge, HR; Groot, JA; van den Berghe, N | 1 |
| Akiguchi, I; Izumi, M; Nagataki, S | 1 |
| Bryant, SH; Camerino, DC; Tricarico, D; Wagner, R | 1 |
| Goda, S; Goto, I; Kobayashi, T; Yoshimura, T | 1 |
| Detimary, P; Gao, ZY; Gembal, M; Gilon, P; Henquin, JC | 1 |
| Buxton, IL; Zhang, L | 1 |
| Heppel, LA; Huang, NN; Wang, DJ | 1 |
| Horsburgh, K; Inglis, FM; McCulloch, J | 1 |
| Araki, T; Fujiwara, T; Itoyama, Y; Kato, H | 1 |
| Dietrich, C; Kilbinger, H | 1 |
| Dawson, JJ; Iannazzo, L; Majewski, H | 1 |
| Hori, M; Ikuhara, T; Isogai, Y; Matsuzaki, K; Nakamura, I; Suda, T; Suzuki, H; Takahashi, N | 1 |
| Cheung, CY; Marley, PD; Murphy, R; Thomson, KA | 1 |
| Bachoo, M; Polosa, C; Zhang, C | 1 |
| Bonci, A; Williams, JT | 1 |
| Nash, MS; Osborne, NN; Wood, JP | 1 |
| Handwerger, S; Jikihara, H; Poisner, AM | 1 |
| Warashina, A | 1 |
| Borin, ML | 1 |
| Aperia, A; Cheng, XJ; Greengard, P; Höög, JO; Nairn, AC | 1 |
| Bennett, DJ; Beuerman, RW; Meneray, MA; Nguyen, DH | 1 |
| Dean, B; Hill, C; Keks, N; Opeskin, K; Pavey, G | 1 |
| Hiramatsu, Y; Murakami, M; Yoshimura, K | 1 |
| Ho, IK; Oh, S; Wellman, SE | 1 |
| Bornefalk, E; Ljunggren, O; Ljunghall, S | 1 |
| Conn, PJ; Macek, TA; Schaffhauser, H | 1 |
| Goldstein, JL; Layden, TJ; Moyer, MP; Nataraja, SG; Rao, MC; Sahi, J | 1 |
| Crooke, ST; Levesque, L | 1 |
| Ho, IK; Jang, CG; Rockhold, RW | 1 |
| Bukowski, R; Cathcart, MK; Finke, J; Kolenko, V; O'Shea, J; Rayman, P; Roy, B; Rybicki, L; Tubbs, R | 1 |
| Emiliozzi, C; Mograbi, B; Rochet, N; Rossi, B | 1 |
| Araki, T; Itoyama, Y; Kato, H; Mizugaki, M; Tanji, H | 1 |
| Hsu, KS; Huang, CC | 1 |
| Ambrosini, A; Barassi, A; Racagni, G; Sturani, E; Tininini, S; Zippel, R | 1 |
| Coussin, F; Macrez, N; Mironneau, J; Morel, JL; Viard, P | 1 |
| Berggren, PO; Hansson, A; Larsson, O; Sjöholm, A; Tally, M; Welsh, N; Zhang, Q | 1 |
| Diao, C; Hollenberg, MD; Matsubara, S; Wong, NC; Zheng, XL | 1 |
| Du, XY; Finley, J; Sorota, S | 1 |
| Dyer, JR; Sossin, WS | 1 |
| Checler, F; Frobert, Y; Grassi, J; Lehmann, S; Paitel, E; Vincent, B | 1 |
| Franceschi, RT; McCauley, LK; Ouyang, H; Somerman, MJ; Wang, D | 1 |
| Björkman, T; Brändström, H; Ljunggren , O | 1 |
| Bajnath, RB; Bouritius, H; Groot, JA; Oprins, JC | 1 |
| Hashimoto, K; Igarashi, T; Imai, T; Mitani, A; Nakazawa, T; Noguchi, K; Otsuka, K; Saitoh, M; Shigenobu, K; Someya, S; Tanaka, H; Tanaka, Y; Yamaki, F | 1 |
| Epstein, RJ; Gulliford, T; Huang, G; Ouyang, X; Smith, G; Zhang, H | 1 |
| Chen, L; Harris, DC; Kairaitis, LK; Wang, Y; Zhang, BH | 1 |
| Deth, RC; Sharma, A; Waly, M | 1 |
| Koda, H; Mizumura, K | 1 |
| Dortch-Carnes, J; Potter, DE | 1 |
| Krymsky, MA; Kudryashov, DS; Lukas, TJ; Shirinsky, VP; Vorotnikov, AV; Watterson, DM | 1 |
| Erlenkamp, S; Glitsch, HG; Kockskämper, J | 1 |
| Brown, EN; Galligan, JJ | 1 |
| Fujita, T; Kumamoto, E; Yang, K | 1 |
| Bespalova, ZhD; Khapchaev, AY; Krymsky, MA; Shirinsky, VP; Sidorova, MV; Vorotnikov, AV; Wang, CL | 1 |
| Bonci, A; Diamond, I; Gonzalez, GF; Hopf, FW; Mailliard, WS | 1 |
| Bayliss, DA; Lei, Q; Murbartián, J; Sando, JJ | 1 |
| Cuevas, J; Katnik, C; Pastoor, T; Pollock, VV; Wecker, L | 1 |
| Chen, YH; Chuang, CM; Huang, SS; Lin, PL; Lu, DY; Lu, GL; Tsai, MC; Yang, HY | 1 |
| Anderson, AA; Child, ES; Elphick, LM; Mann, DJ; Prasad, A | 1 |
| Chang, CY; Jiang, X; Mennerick, S; Moulder, KL | 1 |
| Pacheco, MA; Pastoor, T; Pollock, VV; Wecker, L | 1 |
| Bers, DM; Bossuyt, J; Despa, S; Han, F; Martin, JL | 1 |
| Bishnoi, M; Cao, DS; Evans, MS; Jeffry, JA; Pabbidi, RM; Pimentel, F; Premkumar, LS; Raisinghani, M; Zhong, L | 1 |
| Froehlich, O; Klein, JD; Sands, JM; Wang, Y | 1 |
1 review(s) available for phorbol 12,13-dibutyrate and colforsin
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
168 other study(ies) available for phorbol 12,13-dibutyrate and colforsin
| Article | Year |
|---|---|
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Ba2+ current oscillations modulated by cyclic AMP and phorbol esters in ras-transformed fibroblasts.
Topics: 3T3 Cells; Animals; Barium; Bradykinin; Bucladesine; Cell Line, Transformed; Colforsin; Cyclic AMP; Evoked Potentials; Genes, ras; Kinetics; Kirsten murine sarcoma virus; Membrane Potentials; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Time Factors | 1992 |
Synergistic and coordinate expression of the genes encoding ribonucleotide reductase subunits in Swiss 3T3 cells: effect of multiple signal-transduction pathways.
Topics: 3T3 Cells; Animals; Bombesin; Cell Division; Colforsin; Cyclic AMP; Epidermal Growth Factor; Gene Expression Regulation; Growth Substances; Insulin; Mice; Phorbol 12,13-Dibutyrate; Ribonucleotide Reductases; RNA, Messenger; Signal Transduction; Vasopressins | 1992 |
Ion transport characteristics of the murine trachea and caecum.
Topics: Amiloride; Animals; Bumetanide; Cecum; Chlorides; Colforsin; Cystic Fibrosis; Electric Conductivity; In Vitro Techniques; Male; Mice; Mice, Transgenic; Phorbol 12,13-Dibutyrate; Pyridazines; Sodium; Trachea | 1992 |
Mapping of second messenger and rolipram receptors in mammalian brain.
Topics: Animals; Autoradiography; Brain Ischemia; Brain Mapping; Colforsin; Cyclic AMP; Gerbillinae; Hippocampus; In Vitro Techniques; Male; Phorbol 12,13-Dibutyrate; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Drug; Rolipram; Second Messenger Systems | 1992 |
Induction of tolerance to ischemia: alterations in second-messenger systems in the gerbil hippocampus.
Topics: Animals; Autoradiography; Brain Ischemia; Colforsin; Cyclic AMP; Gerbillinae; Hippocampus; Inosine Triphosphate; Male; Phorbol 12,13-Dibutyrate; Phosphodiesterase Inhibitors; Protein Kinases; Pyrrolidinones; Rolipram; Second Messenger Systems | 1992 |
Characterization of a metabotropic glutamate receptor: direct negative coupling to adenylyl cyclase and involvement of a pertussis toxin-sensitive G protein.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Alanine; Alkaloids; Animals; Cell Membrane; Cells, Cultured; Colforsin; Corpus Striatum; Cycloleucine; Glutamates; Glutamic Acid; GTP-Binding Proteins; In Vitro Techniques; Mice; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Protein Kinase C; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Signal Transduction; Staurosporine; Virulence Factors, Bordetella | 1992 |
The expression of 80K/MARCKS, a major substrate of protein kinase C (PKC), is down-regulated through both PKC-dependent and -independent pathways. Effects of bombesin, platelet-derived growth factor, and cAMP.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Blotting, Northern; Bombesin; Cell Nucleus; Colforsin; Cyclic AMP; Enzyme Activation; Homeostasis; Insulin; Intracellular Signaling Peptides and Proteins; Kinetics; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Phorbol 12,13-Dibutyrate; Platelet-Derived Growth Factor; Protein Kinase C; Proteins; RNA, Messenger; Time Factors; Transcription, Genetic | 1992 |
Alteration of second-messenger ligand binding following 2-hr hemispheric ischemia in the gerbil brain.
Topics: Adenylyl Cyclases; Animals; Antipyrine; Autoradiography; Brain; Carbon Radioisotopes; Carotid Artery, Common; Colforsin; Female; Gerbillinae; Ischemic Attack, Transient; Ligands; Male; Organ Specificity; Phorbol 12,13-Dibutyrate; Protein Kinase C; Regional Blood Flow; Second Messenger Systems; Time Factors; Tritium | 1992 |
Regulation of apical Cl- conductance and basolateral K+ conductances by phorbol esters in HT-29cl.19A cells.
Topics: Calcium; Carcinoma; Cell Membrane; Chlorides; Colforsin; Colonic Neoplasms; Electric Conductivity; Humans; Phorbol 12,13-Dibutyrate; Potassium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Reversal by increased CSF [H+] and [K+] of phorbol ester-induced arteriolar constriction in piglets.
Topics: Animals; Animals, Newborn; Arterioles; Colforsin; Hydrogen; Hypercapnia; Indomethacin; Isoproterenol; Osmolar Concentration; Phorbol 12,13-Dibutyrate; Pia Mater; Potassium; Swine; Vasoconstriction; Vasodilation | 1992 |
Second-messenger regulation of sodium transport in mammalian airway epithelia.
Topics: Animals; Bronchi; Calcimycin; Colforsin; Culture Techniques; Epithelium; Humans; Ion Transport; Phorbol 12,13-Dibutyrate; Phosphodiesterase Inhibitors; Pyridazines; Sheep; Sodium; Trachea | 1992 |
Protective effect of a novel vinca alkaloid derivative, vinconate, against alterations in binding sites of second messengers after transient cerebral ischemia in gerbils.
Topics: Animals; Binding Sites; Brain; Colforsin; Corpus Striatum; Gerbillinae; Hippocampus; Injections, Intraperitoneal; Inositol 1,4,5-Trisphosphate; Ischemic Attack, Transient; Male; Phorbol 12,13-Dibutyrate; Second Messenger Systems; Vinca Alkaloids | 1992 |
Modulation of IL-2- and IL-4-dependent human B cell proliferation by cyclic AMP.
Topics: B-Lymphocytes; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Humans; Interleukin-2; Interleukin-4; Lymphocyte Activation; Phorbol 12,13-Dibutyrate | 1991 |
Autoradiographic analysis of second messenger and neurotransmitter system receptors in the gerbil hippocampus following transient forebrain ischemia.
Topics: Adenosine; Adenylyl Cyclases; Animals; Autoradiography; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Colforsin; Gerbillinae; Hippocampus; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ischemic Attack, Transient; Isradipine; Male; Neurons; Organ Specificity; Oxadiazoles; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyramidal Tracts; Quinuclidinyl Benzilate; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Muscarinic; Receptors, Purinergic; Second Messenger Systems; Time Factors; Tritium | 1991 |
Chronic muscarinic stimulation of SH-SY5Y neuroblastoma cells suppresses inositol 1,4,5-trisphosphate action. Parallel inhibition of inositol 1,4,5-trisphosphate-induced Ca2+ mobilization and inositol 1,4,5-trisphosphate binding.
Topics: Calcium; Calcium Channels; Carbachol; Cell Line; Cell Membrane; Cell Membrane Permeability; Colforsin; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Kinetics; Neuroblastoma; Phorbol 12,13-Dibutyrate; Plant Extracts; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Terpenes; Thapsigargin; Tretinoin | 1991 |
Protein kinase C activating phorbolesters enhance the cyclic AMP response to parathyroid hormone, forskolin and choleratoxin in mouse calvarial bones and rat osteosarcoma cells.
Topics: Adenylyl Cyclases; Animals; Bone and Bones; Cattle; Cholera Toxin; Colforsin; Culture Techniques; Cyclic AMP; Enzyme Activation; Mice; Osteosarcoma; Parathyroid Hormone; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Characterization of the glycogenolysis elicited by vasoactive intestinal peptide, noradrenaline and adenosine in primary cultures of mouse cerebral cortical astrocytes.
Topics: Adenosine; Animals; Astrocytes; Bucladesine; Cells, Cultured; Cerebral Cortex; Colforsin; Energy Metabolism; Glycogen; Mice; Norepinephrine; Phorbol 12,13-Dibutyrate; Vasoactive Intestinal Peptide | 1991 |
Activation of PKC inhibits NaF-induced inositol phospholipid turnover in rat insulinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Inositol Phosphates; Insulin; Insulin Secretion; Insulinoma; Kinetics; Pancreatic Neoplasms; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Rats; Sodium Fluoride; Tumor Cells, Cultured | 1990 |
Xenopus oocyte K+ current. III. Phorbol esters and pH regulate current at gap junctions.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; Female; Follicle Stimulating Hormone; Hydrogen-Ion Concentration; Intercellular Junctions; Isoproterenol; Kinetics; Mathematics; Models, Biological; Oocytes; Phorbol 12,13-Dibutyrate; Potassium Channels; Xenopus laevis | 1990 |
Multiple synergistic signal transduction pathways regulate c-fos expression in Swiss 3T3 cells: the role of cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bombesin; Calcimycin; Colforsin; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Signal Transduction; Transcription, Genetic | 1990 |
Stimulation of chicken growth hormone release by phorbol esters.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Growth Hormone; Growth Hormone-Releasing Hormone; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pituitary Gland, Anterior; Protein Kinase C; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1990 |
Chloride channel regulation in the skeletal muscle of normal and myotonic goats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Membrane Permeability; Chlorides; Cholera Toxin; Colforsin; Cyclic AMP; Electric Conductivity; Female; Goats; Ion Channels; Isoquinolines; Male; Membrane Potentials; Muscles; Myotonia; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Staurosporine; Tetrahydropapaveroline | 1991 |
Involvement of lipid peroxidation and inhibitory mechanisms on ischemic neuronal damage in gerbil hippocampus: quantitative autoradiographic studies on second messenger and neurotransmitter systems.
Topics: Adenosine; Animals; Autoradiography; Body Temperature; Brain Ischemia; Calcium Channels; Chlorides; Colforsin; Gerbillinae; Hippocampus; Inositol 1,4,5-Trisphosphate; Ion Channels; Lipid Peroxidation; Male; Neurons; Neurotransmitter Agents; Pentobarbital; Phorbol 12,13-Dibutyrate; Quinazolines; Quinuclidinyl Benzilate; Receptors, GABA-A; Second Messenger Systems | 1991 |
Differential alterations of second messenger systems and cerebral glucose use following excitotoxic lesion of rat cerebral cortex.
Topics: Animals; Autoradiography; Brain Chemistry; Cerebral Cortex; Colforsin; Deoxyglucose; Glucose; Glutamates; Ibotenic Acid; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Second Messenger Systems; Staining and Labeling; Visual Cortex | 1991 |
Autoradiographic analysis of second-messenger systems in the gerbil hippocampus following repeated brief ischemic insults.
Topics: Animals; Autoradiography; Brain Ischemia; Colforsin; Gerbillinae; Hippocampus; Inositol 1,4,5-Trisphosphate; Male; Phorbol 12,13-Dibutyrate; Second Messenger Systems | 1991 |
Autoradiographic localization of binding sites for second messengers on neurones and astrocytes of cultured rat cerebellum.
Topics: Animals; Astrocytes; Autoradiography; Binding Sites; Cerebellum; Colforsin; Inositol 1,4,5-Trisphosphate; Nerve Fibers; Neurons; Organ Culture Techniques; Phorbol 12,13-Dibutyrate; Purkinje Cells; Rats; Second Messenger Systems | 1991 |
Tricyclic antidepressants inhibit Ca(2+)-activated K(+)-efflux in cultured spinal cord neurons.
Topics: Adenylate Cyclase Toxin; Animals; Antidepressive Agents, Tricyclic; Calcimycin; Calcium; Cells, Cultured; Colforsin; Desipramine; Embryo, Mammalian; Female; Kinetics; Male; Mice; Mice, Inbred C57BL; Neurons; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Potassium; Potassium Channels; Rubidium; Spinal Cord; Virulence Factors, Bordetella | 1991 |
Interleukin-2-induced DNA synthesis and immunoglobulin secretion by resting human tonsillar B cells: effects of protein kinase C activation.
Topics: B-Lymphocytes; Cells, Cultured; Colforsin; DNA; Enzyme Activation; Humans; Immunoglobulin G; Immunoglobulin M; Interleukin-2; Interleukin-6; Ionomycin; Lymphocyte Activation; Palatine Tonsil; Phorbol 12,13-Dibutyrate; Protein Kinase C | 1991 |
Alterations of functional glucose use and ligand binding to second messenger systems following unilateral orbital enucleation.
Topics: Adenylyl Cyclases; Animals; Autoradiography; Colforsin; Denervation; Eye Enucleation; Geniculate Bodies; Glucose; Glutamates; Ligands; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Second Messenger Systems; Superior Colliculi | 1991 |
Neuronal localization of cannabinoid receptors and second messengers in mutant mouse cerebellum.
Topics: Adenylyl Cyclases; Animals; Autoradiography; Cannabinoids; Cerebellum; Colforsin; Cyclohexanols; Heterozygote; Homozygote; Mice; Mice, Neurologic Mutants; Neurons; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Cannabinoid; Receptors, Drug; Second Messenger Systems; Tritium | 1991 |
Further evidence for abnormal protein kinase C regulation of macromolecule secretion in fibroblasts from cystic fibrosis patients.
Topics: Binding Sites; Bucladesine; Calcimycin; Cells, Cultured; Colforsin; Cystic Fibrosis; Dose-Response Relationship, Drug; Fibroblasts; Glycoconjugates; Humans; Isoproterenol; Phorbol 12,13-Dibutyrate; Protein Kinase C; Skin; Tetradecanoylphorbol Acetate | 1990 |
Discriminatory effects of forskolin and EGTA on the indirect cyclic AMP responses to histamine, noradrenaline, 5-hydroxytryptamine, and glutamate in guinea-pig cerebral cortical slices.
Topics: Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Egtazic Acid; Glutamates; Glutamic Acid; Guinea Pigs; Histamine; In Vitro Techniques; Inositol Phosphates; Neurotransmitter Agents; Norepinephrine; Phorbol 12,13-Dibutyrate; Serotonin | 1990 |
Autoradiographic analysis on second-messenger systems and local cerebral blood flow in ischemic gerbil brain.
Topics: Adenylyl Cyclases; Animals; Autoradiography; Blood Flow Velocity; Brain; Cerebral Cortex; Cerebrovascular Circulation; Colforsin; Female; Functional Laterality; Gerbillinae; Ischemic Attack, Transient; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Regression Analysis; Second Messenger Systems | 1991 |
Identification of a prominent 85-kDa cAMP-dependent phosphoprotein associated with late G1 phase in mitogen-stimulated B lymphocytes.
Topics: Animals; B-Lymphocytes; Catalysis; Colforsin; Cyclic AMP; Electrophoresis, Gel, Two-Dimensional; G1 Phase; Ionomycin; Mice; Mitogens; Molecular Weight; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Protein Kinases | 1991 |
Post- and presynaptic lesions in the CA1 region of hippocampus: effect on [3H]forskolin and [3H]phorboldibutyrate ester binding.
Topics: Adenylyl Cyclases; Animals; Colforsin; Enzyme Activation; Hippocampus; Humans; Injections, Intraventricular; Ischemic Attack, Transient; Kainic Acid; Male; Neurons; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred Strains; Second Messenger Systems | 1991 |
Possible involvement of protein kinase C and cyclic AMP-dependent protein kinase in the sodium fluoride-mediated inhibition of cyclic nucleotide accumulation in smooth muscle cells.
Topics: Animals; Cells, Cultured; Colforsin; Cytosol; Diglycerides; Kinetics; Muscle, Smooth, Vascular; Nucleotides, Cyclic; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinases; Rats; Sodium Fluoride | 1990 |
Second messenger systems: functional role in cerebrovascular smooth muscle regulation.
Topics: Animals; Cats; Cerebral Arteries; Cerebral Veins; Colforsin; Dinoprost; Male; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Second Messenger Systems; Vasoconstriction | 1990 |
Effect of growth hormone and serum on the expression of the proto-oncogenes c-jun and c-fos in insulin producing cells.
Topics: Adenylyl Cyclases; Animals; Blood; Colforsin; Cycloheximide; DNA Probes; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation; Insulin; Insulinoma; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Somatomedins; Transcription Factors; Tumor Cells, Cultured | 1990 |
Forskolin mediates the survival of nerve growth factor-dependent sympathetic neurons of chick embryo by a cyclic AMP-independent mechanism.
Topics: Animals; Biomechanical Phenomena; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP; Down-Regulation; Nerve Growth Factors; Neurons; Phorbol 12,13-Dibutyrate; Sympathetic Nervous System; Time Factors | 1990 |
Neural blockade in basal and postreceptor-stimulated intestinal transport.
Topics: Absorption; Animals; Biological Transport; Colforsin; Electrolytes; Intestinal Mucosa; Nerve Block; Perfusion; Phorbol 12,13-Dibutyrate; Pressure; Rabbits; Receptors, Cell Surface; Tetrodotoxin; Time Factors; Water | 1990 |
Evidence for involvement of protein kinase C and cyclic adenosine 3',5' monophosphate-dependent protein kinase in the 1,25-dihydroxy-vitamin D3-mediated rapid stimulation of intestinal calcium transport, (transcaltachia).
Topics: Alkaloids; Animals; Biological Transport; Calcitriol; Calcium; Chickens; Colforsin; Cyclic AMP; Duodenum; Intestinal Mucosa; Intestines; Kinetics; Male; Nifedipine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil; Vitamin D Deficiency | 1990 |
Effect of ethanol on cyclic AMP levels in intact PC12 cells.
Topics: 2-Chloroadenosine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenal Gland Neoplasms; Animals; Cell Membrane; Colforsin; Cyclic AMP; Ethanol; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Pheochromocytoma; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Tumor Cells, Cultured; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1990 |
Desensitization of vasopressin sensitive adenylate cyclase by vasopressin and phorbol esters.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Arginine Vasopressin; Cell Line; Colforsin; Cyclic AMP; Dogs; Isoproterenol; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Receptors, Angiotensin; Receptors, Vasopressin | 1990 |
Potentiation of oncogenic N-ras-induced neurite outgrowth and ornithine decarboxylase activity by phorbol dibutyrate and protein kinase inhibitor H-8.
Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Colforsin; Dexamethasone; Epidermal Growth Factor; Isoquinolines; Nerve Growth Factors; Neurons; Oncogene Protein p21(ras); Ornithine Decarboxylase; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase Inhibitors; Rats; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1990 |
Chronic regulation of ovarian oxytocin and progesterone release by prostaglandins: opposite effects in bovine granulosa and early luteal cells.
Topics: Alprostadil; Animals; Cattle; Cells, Cultured; Colforsin; Corpus Luteum; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Female; Granulosa Cells; Insulin-Like Growth Factor I; Ovary; Oxytocin; Phorbol 12,13-Dibutyrate; Progesterone | 1990 |
Phorbol esters modulate cyclic AMP accumulation in porcine thyroid cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1988 |
Reduction of the same calcium current component by A and C kinases: differential pertussis toxin sensitivity.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cells, Cultured; Colforsin; Electric Conductivity; Evoked Potentials; Ganglia, Spinal; Ion Channels; Mice; Neurons; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Protein Kinases; Virulence Factors, Bordetella | 1988 |
Adenosine 3',5'-cyclic monophosphate (cAMP) inhibits phorbol ester-induced growth of an IL-2-dependent T cell line.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Cell Division; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; DNA Replication; Humans; Interleukin-2; Kinetics; Phorbol 12,13-Dibutyrate; Recombinant Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
Inhibition by forskolin of insulin-stimulated glucose transport in L6 muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Cells, Cultured; Colforsin; Cyclic AMP; Dideoxyadenosine; Dideoxynucleosides; Glucose; Hexoses; Insulin; Muscles; Phorbol 12,13-Dibutyrate | 1988 |
Phorbol-12,13-dibutyrate antagonizes while forskolin potentiates the presynaptic autoreceptor-mediated inhibition of [3H]-5-hydroxytryptamine release in rat hypothalamic slices.
Topics: 1-Methyl-3-isobutylxanthine; 5-Methoxytryptamine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Drug Interactions; Drug Synergism; Electric Stimulation; Evoked Potentials; Hypothalamus; Indoles; Male; Methiothepin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Polymyxin B; Rats; Rats, Inbred Strains; Serotonin | 1989 |
Second-messenger systems underlying amine and peptide actions on cardiac muscle in the horseshoe crab Limulus polyphemus.
Topics: 1-Methyl-3-isobutylxanthine; Amines; Animals; Catecholamines; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Epinephrine; Heart; Horseshoe Crabs; Myocardial Contraction; Neuropeptides; Norepinephrine; Oligopeptides; Peptides; Phorbol 12,13-Dibutyrate; Protein Kinase C; Second Messenger Systems | 1989 |
Involvement of adenylate cyclase and protein kinase C in the alpha 2-adrenoceptor-mediated inhibition of noradrenaline and 5-hydroxytryptamine release in rat hypothalamic slices.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Antihypertensive Agents; Brimonidine Tartrate; Colforsin; Dioxanes; Electric Stimulation; Hypothalamus; Idazoxan; In Vitro Techniques; Male; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin | 1989 |
Regulation of GH3 pituitary tumour-cell adenylate cyclase activity by activators of protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Bombesin; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Oxotremorine; Phorbol 12,13-Dibutyrate; Pituitary Neoplasms; Protein Kinase C; Tumor Cells, Cultured; Type C Phospholipases; Vasoactive Intestinal Peptide | 1989 |
Evidence for a protein kinase C-directed mechanism in the phorbol diester-induced phospholipase D pathway of diacylglycerol generation from phosphatidylcholine.
Topics: Alkaloids; Animals; Bucladesine; Cell Line; Choline; Colforsin; Diglycerides; Embryo, Mammalian; Fibroblasts; Glycerides; Glycerophospholipids; Hydrolysis; Myristic Acid; Myristic Acids; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phospholipases; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1989 |
Direct regulation of smooth muscle contractile elements by second messengers.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Rats; Rats, Inbred WKY; Second Messenger Systems | 1989 |
Cross-communication between acetylcholine and VIP in controlling catecholamine secretion by affecting cAMP, inositol triphosphate, protein kinase C, and calcium in rat adrenal medulla.
Topics: Acetylcholine; Adrenal Medulla; Animals; Calcium; Catecholamines; Colforsin; Cyclic AMP; Electric Stimulation; In Vitro Techniques; Inositol Phosphates; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Receptors, Cholinergic; Second Messenger Systems; Splanchnic Nerves; Vasoactive Intestinal Peptide | 1989 |
Activation of protein kinase C via the T-cell receptor complex potentiates cyclic AMP responses in T-cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Humans; Inositol; Inositol Phosphates; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes | 1989 |
Cytosolic free calcium in normal somatotropes: effects of forskolin and phorbol ester.
Topics: Animals; Calcium; Colforsin; Cytosol; Egtazic Acid; Growth Hormone-Releasing Hormone; In Vitro Techniques; Kinetics; Male; Phorbol 12,13-Dibutyrate; Pituitary Gland, Anterior; Rats; Reference Values; Somatostatin | 1989 |
The effect of relaxants working through different transduction mechanisms on the tonic contraction produced in rat aorta by 4 beta-phorbol dibutyrate.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Colforsin; Cromakalim; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Parasympatholytics; Phorbol 12,13-Dibutyrate; Pyrroles; Rats; Rats, Inbred Strains; Xanthines | 1989 |
Autoradiographic distribution of forskolin and phorbol ester binding sites in the retina.
Topics: Animals; Autoradiography; Binding Sites; Colforsin; Eye; Humans; In Vitro Techniques; Macaca fascicularis; Male; Organ Specificity; Phorbol 12,13-Dibutyrate; Rats; Rats, Inbred Strains; Retina; Species Specificity; Tritium | 1989 |
Activation of protein kinase C attenuates prostaglandin E2 responses in a colonic cell line.
Topics: Animals; Bucladesine; Cell Line; Cells, Cultured; Colforsin; Colon; Cyclic AMP; Dimethyl Sulfoxide; Dinoprostone; Enzyme Activation; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Protein Kinase C | 1988 |
The mechanism and control of rabbit oviduct fluid formation.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Body Fluids; Bucladesine; Bumetanide; Calcimycin; Cholera Toxin; Colforsin; Fallopian Tubes; Female; Perfusion; Phorbol 12,13-Dibutyrate; Rabbits; Theophylline | 1988 |
Receptor-stimulated system mediated interactions of neuropeptides in GH3 cells.
Topics: Animals; Bucladesine; Cell Line; Colforsin; Glioma; Kinetics; Phorbol 12,13-Dibutyrate; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 1988 |
Phorbol 12,13-dibutyrate increases tyrosine hydroxylase activity in the superior cervical ganglion of the rat.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Dihydroxyphenylalanine; Dimethylphenylpiperazinium Iodide; Ganglia, Sympathetic; Muscarine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Rats; Time Factors; Tyrosine 3-Monooxygenase | 1986 |
Cholinergic regulation of protein phosphorylation in bovine adrenal chromaffin cells.
Topics: Acetylcholine; Adrenal Medulla; Animals; Calcium; Cattle; Cholinergic Fibers; Colforsin; In Vitro Techniques; Molecular Weight; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphoproteins; Tyrosine 3-Monooxygenase | 1988 |
Phorbol-12,13-dibutyrate enhances the cyclic AMP accumulation in rat hippocampal slices induced by adenosine analogues.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate Ribose; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Animals; Colforsin; Cyclic AMP; Hippocampus; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxants, Central; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Rats, Inbred Strains; Vasodilator Agents; Virulence Factors, Bordetella | 1987 |
Protein kinase C activation enhances cAMP accumulation in Swiss 3T3 cells: inhibition by pertussis toxin.
Topics: Adenylate Cyclase Toxin; Alprostadil; Animals; Arginine Vasopressin; Carcinogens; Cells, Cultured; Colforsin; Cyclic AMP; Diglycerides; Kinetics; Mice; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Virulence Factors, Bordetella | 1987 |
[Transmethylation inhibitors prevent the spontaneous reinitiation of meiosis in denuded ovocytes of mice].
Topics: Animals; Carcinogens; Colforsin; Drug Synergism; Female; Meiosis; Methylation; Methyltransferases; Mice; Oocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tubercidin | 1986 |
Autoradiographic analysis of second-messenger systems in the gerbil brain.
Topics: Animals; Autoradiography; Brain; Colforsin; Female; Gerbillinae; Male; Phorbol 12,13-Dibutyrate; Second Messenger Systems; Tissue Distribution | 1988 |
Phorbol ester contracts rabbit thoracic aorta by increasing intracellular calcium and by activating calcium influx.
Topics: Animals; Biological Transport; Calcium; Colforsin; Cytoplasm; Extracellular Space; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prazosin; Protein Kinase C; Rabbits; Time Factors | 1986 |
Inhibition of denuded mouse oocyte meiotic maturation by tumor-promoting phorbol esters and its reversal by retinoids.
Topics: Animals; Colforsin; Diterpenes; Drug Interactions; Female; Meiosis; Mice; Oocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Retinoids; Tetradecanoylphorbol Acetate | 1984 |
Chloride secretion induced by phorbol dibutyrate and forskolin in the human colonic carcinoma cell line HT-29Cl.19A is regulated by different mechanisms.
Topics: Brefeldin A; Chloride Channels; Chlorides; Colforsin; Cyclopentanes; Cystic Fibrosis Transmembrane Conductance Regulator; Demecolcine; Electric Stimulation; HT29 Cells; Humans; Ionophores; Microelectrodes; Nocodazole; Nystatin; Phorbol 12,13-Dibutyrate; Protein Synthesis Inhibitors; Temperature | 1995 |
Signal-transduction pathways causing slow synaptic excitation in guinea pig myenteric AH neurons.
Topics: Animals; Colforsin; Drug Synergism; Electric Conductivity; Enzyme Inhibitors; GTP-Binding Proteins; Guinea Pigs; Male; Myenteric Plexus; Neurons; Peptide Fragments; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Signal Transduction; Substance P; Synapses; Virulence Factors, Bordetella | 1995 |
Noradrenergic regulation of c-jun expression in the rat pineal gland in culture: positive and negative components.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Gene Expression Regulation; Isoquinolines; Male; Norepinephrine; Organ Culture Techniques; Phorbol 12,13-Dibutyrate; Pineal Gland; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; RNA, Messenger; Sulfonamides | 1993 |
Serotonin and acetylcholine: further analysis of praziquantel-induced contraction of magnesium-paralysed Schistosoma mansoni.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Amifampridine; Animals; Arecoline; Carbachol; Colforsin; Dose-Response Relationship, Drug; In Vitro Techniques; Ions; Magnesium; Male; Muscle Contraction; Paralysis; Phorbol 12,13-Dibutyrate; Praziquantel; Schistosoma mansoni; Serotonin | 1993 |
P0 phosphorylation in nerves from normal and diabetic rats: role of protein kinase C and turnover of phosphate groups.
Topics: Animals; Basal Metabolism; Colforsin; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Down-Regulation; Drug Antagonism; Male; Myelin P0 Protein; Myelin Proteins; Phorbol 12,13-Dibutyrate; Phosphates; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reference Values; Sciatic Nerve | 1994 |
Dissociation between changes in cytoplasmic free Ca2+ concentration and insulin secretion as evidenced from measurements in mouse single pancreatic islets.
Topics: Animals; Biological Transport; Calcium; Cell Compartmentation; Colforsin; Cytoplasm; Enzyme Inhibitors; Ethers, Cyclic; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Membranes; Mice; Mice, Obese; Okadaic Acid; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1995 |
Cytosolic free Ca2+ oscillations induced by diadenosine 5',5"'-P1,P3-triphosphate and diadenosine 5',5"'-P1,P4-tetraphosphate in single rat hepatocytes are indistinguishable from those induced by ADP and ATP respectively.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cytosol; Dinucleoside Phosphates; Diterpenes; Kinetics; Liver; Male; Phorbol 12,13-Dibutyrate; Rats; Rats, Wistar; Time Factors | 1995 |
Regulation of cyclic AMP levels by phorbol esters in bovine adrenal medullary cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adrenal Medulla; Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Indoles; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Virulence Factors, Bordetella | 1993 |
Chloride channels in myocytes from rabbit colon are regulated by a pertussis toxin-sensitive G protein.
Topics: Animals; Bucladesine; Calcimycin; Cell Adhesion; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Colon; Cytosol; Diglycerides; Electric Conductivity; Electrophysiology; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Ion Channels; Ionomycin; Male; Meglumine; Membrane Potentials; Membrane Proteins; Muscle, Smooth; NAD; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Rabbits; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Tetraethylammonium; Tetraethylammonium Compounds; Virulence Factors, Bordetella | 1993 |
Transcriptional down-regulation of m2 muscarinic receptor gene expression in human embryonic lung (HEL 299) cells by protein kinase C.
Topics: Blotting, Northern; Cell Line; Cell Nucleus; Colforsin; Cycloheximide; Dactinomycin; Embryo, Mammalian; Gene Expression Regulation; Half-Life; Humans; Indoles; Kinetics; Lung; Maleimides; N-Methylscopolamine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; RNA, Messenger; Scopolamine Derivatives; Time Factors; Transcription, Genetic | 1995 |
Expression of leukaemia inhibitory factor/cholinergic differentiation factor is linked to adrenoceptor stimulation.
Topics: Animals; Colforsin; Gene Expression; Growth Inhibitors; Homeostasis; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Male; Norepinephrine; Organ Culture Techniques; Phorbol 12,13-Dibutyrate; Pineal Gland; Pituitary Gland; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superior Cervical Ganglion | 1995 |
Multiple intracellular signallings are involved in thyrotropin-releasing hormone (TRH)-induced c-fos and jun B mRNA levels in clonal prolactin cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Clone Cells; Colforsin; Cyclic AMP; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Ionomycin; Neoplasm Proteins; Nuclear Proteins; Phorbol 12,13-Dibutyrate; Pituitary Gland, Anterior; Pituitary Neoplasms; Prolactin; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1995 |
Mutual antagonistic interactions between the thyrotropin (adenosine 3',5'-monophosphate) and protein kinase C/epidermal growth factor (tyrosine kinase) pathways in cell proliferation and differentiation of cultured human thyroid follicles.
Topics: Alkaloids; Cell Differentiation; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Epidermal Growth Factor; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein-Tyrosine Kinases; Second Messenger Systems; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1995 |
Agonist-induced desensitization of histamine H1 receptor-mediated inositol phospholipid hydrolysis in human umbilical vein endothelial cells.
Topics: Alkaloids; Cells, Cultured; Colforsin; Endothelium, Vascular; Histamine; Humans; Hydrolysis; Indoles; Nitroprusside; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Receptors, Histamine H1; Sodium Fluoride; Staurosporine; Umbilical Veins | 1994 |
Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of intracellular Ca2+ in the histamine H1 receptor-stimulated phosphorylation of Ser8, Ser19, Ser31, and Ser40.
Topics: Adrenal Medulla; Animals; Caffeine; Calcium; Cattle; Colforsin; Ionomycin; Peptide Mapping; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphoserine; Receptors, Histamine H1; Receptors, Nicotinic; Signal Transduction; Tyrosine 3-Monooxygenase | 1995 |
Presynaptic enhancement of inhibitory synaptic transmission by protein kinases A and C in the rat hippocampus in vitro.
Topics: Animals; Cadmium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Electrophysiology; Hippocampus; In Vitro Techniques; Kinetics; Neural Inhibition; Phorbol 12,13-Dibutyrate; Presynaptic Terminals; Protein Kinase C; Rats; Synaptic Transmission | 1995 |
Age-dependent changes in second messenger and rolipram receptor systems in the gerbil brain.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Aging; Animals; Autoradiography; Brain; Brain Chemistry; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gerbillinae; Inositol 1,4,5-Trisphosphate; Male; Phorbol 12,13-Dibutyrate; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, Drug; Rolipram; Second Messenger Systems | 1994 |
Heterologous sensitization of adenylate cyclase activity by serotonin in the rat cerebral cortex.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Cerebral Cortex; Colforsin; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Phorbol 12,13-Dibutyrate; Propanolamines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Somatostatin; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1993 |
Activators of protein kinase A stimulate apical but not basolateral transport in epithelial Madin-Darby canine kidney cells.
Topics: Alkaloids; Aluminum Compounds; Animals; Biological Transport; Cell Line; Cell Membrane; Cell Polarity; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dogs; Endoplasmic Reticulum; Enzyme Activation; Epithelium; Fluorides; Golgi Apparatus; GTP-Binding Proteins; Hemagglutinins; In Vitro Techniques; Kidney; Membrane Glycoproteins; Phorbol 12,13-Dibutyrate; Phosphoproteins; Staurosporine; Viral Envelope Proteins | 1994 |
Aging and chloride channel regulation in rat fast-twitch muscle fibres.
Topics: Aging; Animals; Calcimycin; Chloride Channels; Chlorides; Cholera Toxin; Colforsin; Electric Conductivity; Male; Muscle Contraction; Muscles; Phorbol 12,13-Dibutyrate; Potassium; Rats; Rats, Wistar; Time Factors; Toes; Virulence Factors, Bordetella | 1994 |
Enhanced maximal binding capacity (Bmax) of second messenger ligand in the acute phase of cerebral ischemia--direct visualization by digital image analysis.
Topics: Acute Disease; Animals; Autoradiography; Brain Ischemia; Cerebrovascular Circulation; Colforsin; Female; Gerbillinae; Image Processing, Computer-Assisted; Ligands; Male; Phorbol 12,13-Dibutyrate; Second Messenger Systems | 1994 |
Renal tubular dopamine outward transfer during Na(+)-H+ exchange activation by alpha 1- and alpha 2-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Amiloride; Animals; Bucladesine; Colforsin; Dopamine; Hydrogen; In Vitro Techniques; Kidney Tubules; Levodopa; Phenylephrine; Phorbol 12,13-Dibutyrate; Quinoxalines; Rats; Sodium; Sphingosine | 1993 |
Regulation of isotonic shortening velocity by second messengers in tracheal smooth muscle.
Topics: Animals; Calcium; Colforsin; Dogs; Electrophysiology; Intracellular Membranes; Isotonic Contraction; Muscle, Smooth; Myosins; Osmolar Concentration; Phorbol 12,13-Dibutyrate; Phosphorylation; Potassium Chloride; Second Messenger Systems; Stress, Mechanical; Time Factors; Trachea | 1994 |
Cyclic AMP- and phorbol ester-regulated Cl- permeabilities in primary cultures of human and rabbit colonocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Biological Transport; Bumetanide; Carrier Proteins; Cell Membrane Permeability; Cell Separation; Cells, Cultured; Chlorides; Colforsin; Colon; Cyclic AMP; Fluorescent Dyes; Furosemide; Humans; Indomethacin; Kinetics; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rabbits; Rectum; Sodium-Potassium-Chloride Symporters; Spectrometry, Fluorescence; Time Factors | 1994 |
Phorbol ester sequentially downregulates cAMP-regulated basolateral and apical Cl- transport pathways in T84 cells.
Topics: Biological Transport; Carrier Proteins; Cell Line; Cell Membrane; Chlorides; Colforsin; Colon; Cyclic AMP; Electrophysiology; Humans; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Inhibition of myosin light chain phosphatase during Ca(2+)-independent vasocontraction.
Topics: Animals; Aorta, Thoracic; Calcium; Colforsin; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbols; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Rats; Rats, Wistar; Vasoconstriction; Vasodilator Agents | 1993 |
Adenosine reduces the potassium conductance of guinea pig submucosal plexus neurons by activating protein kinase A.
Topics: 2-Chloroadenosine; Adenosine; Alkaloids; Animals; Cadmium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Guinea Pigs; Membrane Potentials; Neurons; Phorbol 12,13-Dibutyrate; Potassium; Staurosporine; Submucous Plexus | 1993 |
Synergistic activation of non-rectifying small-conductance chloride channels by forskolin and phorbol esters in cell-attached patches of the human colon carcinoma cell line HT-29cl.19A.
Topics: Anions; Chloride Channels; Chlorides; Colforsin; Colonic Neoplasms; Cyclic AMP; Drug Synergism; Electric Conductivity; Gluconates; Humans; Iodides; Membrane Potentials; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinases; Tumor Cells, Cultured | 1993 |
Activation of ion transport by combined effects of ionomycin, forskolin and phorbol ester on cultured HT-29cl.19A human colonocytes.
Topics: Biological Transport; Calcium; Carbachol; Chloride Channels; Colforsin; Colonic Neoplasms; Cyclic AMP; Drug Synergism; Electric Conductivity; Humans; Ionomycin; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C; Tumor Cells, Cultured | 1993 |
Effects of phorbol ester on protein kinase C activity and effects of depletion of its activity on thyrotrophin, forskolin and 8'-bromoadenosine 3',5'-cyclic monophosphate-induced [3H]thymidine incorporation in rat FRTL-5 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Colforsin; Cytosol; DNA; Dose-Response Relationship, Drug; Down-Regulation; Drug Administration Schedule; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Thymidine; Thyroid Gland; Thyrotropin | 1993 |
Reduction in second-messenger ligand binding sites after brain ischemia--autoradiographic Bmax and Kd determinations using digital image analysis.
Topics: Adenylyl Cyclases; Animals; Antipyrine; Autoradiography; Blood Pressure; Brain Ischemia; Carbon Radioisotopes; Cerebrovascular Circulation; Colforsin; Corpus Striatum; Female; Gerbillinae; Kinetics; Ligands; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Reference Values; Regional Blood Flow; Second Messenger Systems; Tritium | 1993 |
Regulation of resting ionic conductances in frog skeletal muscle.
Topics: Adenylyl Cyclases; Alkaloids; Animals; Chlorides; Colforsin; Electric Conductivity; Electrophysiology; Enzyme Activation; Muscles; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Rana esculenta; Staurosporine | 1993 |
Involvement of protein kinase C in the proliferation of cultured Schwann cells.
Topics: Animals; Cell Division; Cells, Cultured; Colforsin; Drug Synergism; Enzyme Activation; Glia Maturation Factor; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Schwann Cells; Signal Transduction | 1993 |
Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Diazoxide; Diterpenes; Glucose; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Mice; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Potassium; Potassium Channels; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate | 1993 |
Protein kinase regulation of muscarinic receptor signalling in colonic smooth muscle.
Topics: Animals; Binding, Competitive; Carbachol; Colforsin; Colon; Cyclic AMP; Dogs; Female; GTP-Binding Proteins; Male; Membranes; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Protein Kinases; Radioligand Assay; Receptors, Muscarinic; Signal Transduction | 1993 |
Postischemic changes of intracellular second messengers in the gerbil brain after long-term survival: an autoradiographic study.
Topics: Animals; Autoradiography; Brain Chemistry; Brain Ischemia; Colforsin; Cyclic AMP; Gerbillinae; Inosine Triphosphate; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Second Messenger Systems | 1993 |
Stimulation of aged human lung fibroblasts by extracellular ATP via suppression of arachidonate metabolism.
Topics: Adenosine Triphosphate; Arachidonic Acid; Bradykinin; Cell Division; Cell Line; Cellular Senescence; Colforsin; Cyclic AMP; Dinoprostone; DNA Replication; Embryo, Mammalian; Fibroblasts; Humans; Insulin; Kinetics; Lung; Lysophospholipids; Phorbol 12,13-Dibutyrate; Protein Kinase C; Time Factors | 1993 |
Up-regulation of beta 1-adrenoceptor messenger ribonucleic acid in the rat pineal gland: nocturnally, through a beta-adrenoceptor-linked mechanism, and in vitro, through a novel posttranscriptional mechanism activated by specific protein synthesis inhibit
Topics: Animals; Anisomycin; Base Sequence; Blotting, Northern; Circadian Rhythm; Colforsin; Cycloheximide; Gene Expression Regulation; GTP-Binding Proteins; Male; Molecular Sequence Data; Organ Culture Techniques; Phorbol 12,13-Dibutyrate; Pineal Gland; Propranolol; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; RNA, Messenger; Transcription, Genetic | 1993 |
Immobilization stress induces alterations of second-messenger systems in the gerbil brain.
Topics: Adenylyl Cyclases; Animals; Basal Ganglia; Brain; Brain Chemistry; Colforsin; Gerbillinae; Hippocampus; Immobilization; Phorbol 12,13-Dibutyrate; Protein Kinase C; Second Messenger Systems; Stress, Psychological | 1993 |
Focal increases in [3H]forskolin and [3H]phorbol 12,13-dibutyrate binding in the rat brain following lesions of the medial septum.
Topics: Adenylyl Cyclases; Animals; Autoradiography; Brain Chemistry; Brain Injuries; Colforsin; Hippocampus; Histocytochemistry; Ibotenic Acid; Ligands; Male; Phorbol 12,13-Dibutyrate; Protein Binding; Protein Kinase C; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Stereotaxic Techniques | 1993 |
Age-related changes in bindings of second messengers in the rat brain.
Topics: Adenylyl Cyclases; Aging; Animals; Autoradiography; Brain; Brain Chemistry; Carcinogens; Colforsin; Male; Phorbol 12,13-Dibutyrate; Protein Binding; Protein Kinase C; Rats; Rats, Inbred F344; Second Messenger Systems; Tritium | 1995 |
5-HT1A receptor-mediated inhibition of acetylcholine release from guinea pig myenteric plexus: potential mechanisms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Adenylate Cyclase Toxin; Animals; Colforsin; Cyclic AMP; Enzyme Activation; Female; Guinea Pigs; In Vitro Techniques; Male; Myenteric Plexus; Naphthyridines; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phosphodiesterase Inhibitors; Protein Kinase C; Receptors, Serotonin; Serotonin Receptor Agonists; Signal Transduction; Virulence Factors, Bordetella | 1996 |
Muscarinic autoinhibition of acetylcholine release in mouse atria is not transduced through cyclic AMP or protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenylyl Cyclases; Animals; Atrial Function; Atropine; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Heart; Heart Atria; In Vitro Techniques; Male; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; Second Messenger Systems; Staurosporine | 1996 |
Calcitonin-induced changes in the cytoskeleton are mediated by a signal pathway associated with protein kinase A in osteoclasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Animals, Newborn; Bucladesine; Calcitonin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Dentin; Enzyme Activation; Hematopoietic Stem Cells; Male; Mice; Mice, Inbred Strains; Osteoblasts; Phorbol 12,13-Dibutyrate; Protein Kinase C; Signal Transduction; Skull; Tetradecanoylphorbol Acetate; Thionucleotides | 1996 |
Activation of tyrosine hydroxylase by pituitary adenylate cyclase-activating polypeptide (PACAP-27) in bovine adrenal chromaffin cells.
Topics: Animals; Calcium; Carcinogens; Cattle; Chromaffin Cells; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Ganglionic Stimulants; Indoles; Neuropeptides; Neurotransmitter Agents; Nicotine; Phorbol 12,13-Dibutyrate; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Kinase C; Tyrosine 3-Monooxygenase | 1996 |
Long-term depression of a sympathetic ganglionic response to opioids by prolonged synaptic activity and by phorbol esters.
Topics: Action Potentials; Animals; Calcium; Cats; Colforsin; Electric Stimulation; Enkephalin, Methionine; Female; Ganglia, Sympathetic; Hexamethonium; Long-Term Potentiation; Male; Narcotics; Neural Inhibition; Phorbol 12,13-Dibutyrate; Synapses; Synaptic Transmission; Time Factors | 1996 |
Increased probability of GABA release during withdrawal from morphine.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Antagonists; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Interneurons; Morphine; Nerve Tissue Proteins; Organophosphorus Compounds; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Picrotoxin; Receptors, GABA-A; Salicylamides; Serotonin; Signal Transduction; Staurosporine; Strychnine; Substance Withdrawal Syndrome; Tegmentum Mesencephali; Thionucleotides | 1997 |
Protein kinase C activation by serotonin potentiates agonist-induced stimulation of cAMP production in cultured rat retinal pigment epithelial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Isoproterenol; Naphthalenes; Phorbol 12,13-Dibutyrate; Pigment Epithelium of Eye; Protein Kinase C; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Staurosporine | 1997 |
Beta-adrenergic regulation of renin expression in differentiated U-937 monocytic cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Bucladesine; Cell Differentiation; Cell Line; Colforsin; Enzyme Precursors; Gene Expression Regulation; Humans; Macrophages; Monocytes; Phorbol 12,13-Dibutyrate; Receptors, Adrenergic, beta; Renin; Terbutaline | 1997 |
Involvement of protein kinase C in homologous desensitization of histamine-evoked secretory responses in rat chromaffin cells.
Topics: Animals; Calcium; Carcinogens; Catecholamines; Chromaffin Cells; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cytoplasmic Granules; Desensitization, Immunologic; Enzyme Inhibitors; GTP-Binding Proteins; Histamine; Indoles; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Receptors, Histamine H1; Stimulation, Chemical | 1997 |
Roles of PKA and PKC in regulation of Na+ pump activity in vascular smooth muscle cells.
Topics: Animals; Aorta; Arginine Vasopressin; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Homeostasis; Isoproterenol; Kinetics; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Staurosporine | 1997 |
Regulation of rat Na(+)-K(+)-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKA.
Topics: Alanine; Amino Acid Substitution; Animals; Colforsin; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Dichlororibofuranosylbenzimidazole; Enzyme Activation; Homeostasis; Isoenzymes; Kinetics; Mutagenesis, Site-Directed; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Rats; Recombinant Proteins; Serine; Sodium-Potassium-Exchanging ATPase; Thionucleotides; Transfection | 1997 |
Effect of sensory denervation on the structure and physiologic responsiveness of rabbit lacrimal gland.
Topics: Animals; Carbachol; Cells, Cultured; Colforsin; Eye Proteins; Ganglionectomy; Isoproterenol; Lacrimal Apparatus; Male; Phorbol 12,13-Dibutyrate; Rabbits; Sympathomimetics; Trigeminal Ganglion | 1998 |
Changes in protein kinase C and adenylate cyclase in the temporal lobe from subjects with schizophrenia.
Topics: Adenylyl Cyclases; Adult; Aged; Colforsin; Female; Frontal Lobe; Hippocampus; Humans; Male; Middle Aged; Phorbol 12,13-Dibutyrate; Protein Kinase C; Psychiatric Status Rating Scales; Schizophrenia; Temporal Lobe | 1997 |
Cyclic AMP potentiates substance P-induced amylase secretion by augmenting the effect of calcium in the rat parotid acinar cells.
Topics: 1-Methyl-3-isobutylxanthine; 2,4-Dinitrophenol; Amylases; Animals; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Isoproterenol; Male; Parotid Gland; Perfusion; Phorbol 12,13-Dibutyrate; Rats; Rats, Wistar; Substance P; Thapsigargin | 1998 |
Changes in [3H]forskolin binding to adenylate cyclase and [3H]phorbol dibutyrate binding to protein kinase C in pentobarbital tolerant/dependent rats.
Topics: Adenylyl Cyclases; Animals; Brain; Cerebral Ventricles; Colforsin; Drug Tolerance; Infusions, Parenteral; Male; Organ Specificity; Pentobarbital; Phorbol 12,13-Dibutyrate; Protein Binding; Protein Kinase C; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substance-Related Disorders | 1998 |
Bone resorption induced by A23187 is abolished by indomethacin: implications for second messenger utilised by parathyroid hormone.
Topics: Animals; Animals, Newborn; Bone Resorption; Calcimycin; Calcium; Calcium Radioisotopes; Colforsin; Cyclooxygenase Inhibitors; Humans; Indomethacin; Ionophores; Mice; Parathyroid Hormone; Phorbol 12,13-Dibutyrate; Phorbol Esters; Recombinant Proteins; Second Messenger Systems | 1998 |
Protein kinase C and A3 adenosine receptor activation inhibit presynaptic metabotropic glutamate receptor (mGluR) function and uncouple mGluRs from GTP-binding proteins.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Hippocampus; Isoenzymes; Male; Neural Inhibition; Perforant Pathway; Phorbol 12,13-Dibutyrate; Presynaptic Terminals; Protein Kinase C; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Synapses | 1998 |
Cl- transport in an immortalized human epithelial cell line (NCM460) derived from the normal transverse colon.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Bacterial Toxins; Biological Transport; Cell Line, Transformed; Chlorides; Colforsin; Colon; Cyclic AMP; Cyclic GMP; Cystic Fibrosis Transmembrane Conductance Regulator; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Fluorescent Dyes; Histamine; Humans; Intestinal Mucosa; Models, Biological; Phorbol 12,13-Dibutyrate; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic | 1998 |
Depletion of protein kinase C-alpha by antisense oligonucleotides alters beta-adrenergic function and reverses the phorbol ester-induced reduction of isoproterenol-induced adenosine 3'-5'-cyclic monophosphate accumulation in murine Swiss 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cholera Toxin; Colforsin; Cyclic AMP; Indoles; Isoenzymes; Isoproterenol; Maleimides; Mice; Oligonucleotides, Antisense; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Adrenergic, beta; RNA, Messenger | 1998 |
Withdrawal from butorphanol dependence alters binding of [3H]phorbol dibutyrate to protein kinase C, but not of [3H]forskolin to adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Autoradiography; Brain; Brain Chemistry; Butorphanol; Carcinogens; Colforsin; Male; Narcotic Antagonists; Opioid-Related Disorders; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Tritium | 1999 |
Downregulation of JAK3 protein levels in T lymphocytes by prostaglandin E2 and other cyclic adenosine monophosphate-elevating agents: impact on interleukin-2 receptor signaling pathway.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Induction; Gene Expression Regulation; Humans; Interleukin-2; Janus Kinase 3; Phorbol 12,13-Dibutyrate; Protein-Tyrosine Kinases; Receptors, Interleukin-2; Recombinant Proteins; Second Messenger Systems; T-Lymphocytes | 1999 |
Adhesion of human monocytic THP-1 cells to endothelial cell adhesion molecules or extracellular matrix proteins via beta1 integrins regulates heparin binding epidermal growth factor-like growth factor (HB-EGF) expression.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Colforsin; COS Cells; E-Selectin; Endothelium, Vascular; Epidermal Growth Factor; Extracellular Matrix Proteins; Gene Expression Regulation; Heparin; Heparin-binding EGF-like Growth Factor; Humans; Integrin beta1; Intercellular Adhesion Molecule-1; Intercellular Signaling Peptides and Proteins; Monocytes; Phorbol 12,13-Dibutyrate; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Vascular Cell Adhesion Molecule-1 | 1999 |
Alterations of second messenger systems in the rat brain after 6-hydroxydopamine lesions of the medial forebrain bundle.
Topics: Animals; Antiparkinson Agents; Binding Sites; Brain; Carcinogens; Colforsin; Corpus Striatum; Male; Medial Forebrain Bundle; Oxidopamine; Phorbol 12,13-Dibutyrate; Pyrrolidinones; Rats; Rats, Wistar; Rolipram; Second Messenger Systems; Substantia Nigra; Tritium | 1999 |
Protein tyrosine kinase is required for the induction of long-term potentiation in the rat hippocampus.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Long-Term Potentiation; Male; Phenols; Phorbol 12,13-Dibutyrate; Phosphodiesterase Inhibitors; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; src-Family Kinases; Tetraethylammonium | 1999 |
cAMP cascade leads to Ras activation in cortical neurons.
Topics: Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Enzyme Activation; Fetus; Guanosine Triphosphate; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; PC12 Cells; Phorbol 12,13-Dibutyrate; ras GTPase-Activating Proteins; ras Proteins; Rats; Signal Transduction | 2000 |
Beta-3 adrenergic stimulation of L-type Ca(2+) channels in rat portal vein myocytes.
Topics: 1-Propanol; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Barium; Calcium Channels, L-Type; Cells, Cultured; Cholera Toxin; Colforsin; Dose-Response Relationship, Drug; Electric Stimulation; Isoproterenol; Isoquinolines; Membrane Potentials; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Portal Vein; Propanolamines; Rats; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides | 2000 |
Rapid Ca2+ influx and diacylglycerol synthesis in growth hormone-mediated islet beta -cell mitogenesis.
Topics: Animals; Calcium; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cytoplasm; Diglycerides; Enzyme Inhibitors; Fetus; Glucose; Human Growth Hormone; Humans; Islets of Langerhans; Mitogen-Activated Protein Kinases; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Type C Phospholipases; Virulence Factors, Bordetella | 2000 |
Activation of apolipoprotein AI gene expression by protein kinase A and kinase C through transcription factor, Sp1.
Topics: Apolipoprotein A-I; Binding Sites; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Enzyme Activation; Genes, Reporter; Heterotrimeric GTP-Binding Proteins; Humans; Insulin; Phorbol 12,13-Dibutyrate; Promoter Regions, Genetic; Protein Binding; Protein Kinase C; Response Elements; Sequence Deletion; Signal Transduction; Sp1 Transcription Factor; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2000 |
Paucity of CFTR current but modest CFTR immunoreactivity in non-diseased human ventricle.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adult; Animals; Antibodies; Antibody Specificity; Calcium Channels, L-Type; Cell Size; Cells, Cultured; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Dogs; Guinea Pigs; Heart Ventricles; Humans; Immunohistochemistry; Ion Transport; Middle Aged; Myocardium; Phorbol 12,13-Dibutyrate; Protein Kinase C; Species Specificity | 2000 |
Regulation of eukaryotic initiation factor 4E phosphorylation in the nervous system of Aplysia californica.
Topics: Alkaloids; Animals; Aplysia; Benzophenanthridines; Colforsin; Cyclic AMP; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Ganglia, Invertebrate; In Vitro Techniques; Kinetics; Methionine; Mitogen-Activated Protein Kinases; Neurons; p38 Mitogen-Activated Protein Kinases; Peptide Initiation Factors; Phenanthridines; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Biosynthesis; Serotonin; Thionucleotides | 2000 |
Phorbol ester-regulated cleavage of normal prion protein in HEK293 human cells and murine neurons.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Bucladesine; Carcinogens; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Humans; Kinetics; Methanol; Mice; Molecular Sequence Data; Neurons; Phorbol 12,13-Dibutyrate; Phorbol Esters; Precipitin Tests; Prions; Protein Isoforms; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Up-Regulation | 2000 |
Parathyroid hormone-related protein down-regulates bone sialoprotein gene expression in cementoblasts: role of the protein kinase A pathway.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Dental Cementum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Integrin-Binding Sialoprotein; Kinetics; Parathyroid Hormone-Related Protein; Phorbol 12,13-Dibutyrate; Proteins; RNA, Messenger; Second Messenger Systems; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Thionucleotides | 2000 |
Regulation of osteoprotegerin secretion from primary cultures of human bone marrow stromal cells.
Topics: Bone Marrow Cells; Cells, Cultured; Colforsin; Dexamethasone; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Glycoproteins; Humans; Interleukin-1; Osteoprotegerin; Phorbol 12,13-Dibutyrate; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Stromal Cells; Tumor Necrosis Factor-alpha | 2001 |
Neuropeptide Y inhibits the protein kinase C-stimulated Cl(-) secretion in the human colonic cell line HT29cl.19A cell line via multiple sites.
Topics: Calcium; Chlorides; Colforsin; Colonic Neoplasms; Cyclic AMP; Electric Conductivity; HT29 Cells; Humans; Ionomycin; Membrane Potentials; Neuropeptide Y; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C | 2001 |
HNS-32, a novel azulene-1-carboxamidine derivative, inhibits nifedipine-sensitive and -insensitive contraction of the isolated rabbit aorta.
Topics: Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; Calcium Channel Blockers; Colforsin; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Norepinephrine; Phorbol 12,13-Dibutyrate; Potassium Channel Blockers; Potassium Chloride; Protein Kinase C; Pyridines; Rabbits; Tetraethylammonium; Vasoconstrictor Agents; Vasodilator Agents | 2001 |
Association of ErbB2 Ser1113 phosphorylation with epidermal growth factor receptor co-expression and poor prognosis in human breast cancer.
Topics: Animals; Antibodies, Monoclonal; Becaplermin; Breast Neoplasms; Cells, Cultured; Colforsin; Epidermal Growth Factor; ErbB Receptors; Fluorescent Antibody Technique; Humans; Immunoblotting; Mice; Microscopy, Confocal; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphoserine; Platelet-Derived Growth Factor; Prognosis; Proto-Oncogene Proteins c-sis; Receptor, ErbB-2; Transfection; Vanadates | 2001 |
Molecular mechanisms by which iron induces nitric oxide synthesis in cultured proximal tubule cells.
Topics: Animals; Benzoquinones; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Ferric Compounds; Gene Expression Regulation, Enzymologic; Genistein; Iron; Iron Chelating Agents; Kidney Tubules, Proximal; Lactams, Macrocyclic; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrilotriacetic Acid; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein-Tyrosine Kinases; Pyrrolidines; Quinones; Rats; Rats, Wistar; Rifabutin; RNA, Messenger; Thiocarbamates | 2001 |
Protein kinase C regulates dopamine D4 receptor-mediated phospholipid methylation.
Topics: Alkaloids; Benzophenanthridines; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Methylation; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phenanthridines; Phorbol 12,13-Dibutyrate; Phospholipids; Protein Kinase C; Receptors, Dopamine D2; Receptors, Dopamine D4; Thionucleotides; Tumor Cells, Cultured | 2001 |
Sensitization to mechanical stimulation by inflammatory mediators and by mild burn in canine visceral nociceptors in vitro.
Topics: Animals; Bradykinin; Burns; Colforsin; Dinoprostone; Dogs; Histamine; Hot Temperature; Inflammation Mediators; Nociceptors; Phorbol 12,13-Dibutyrate; Physical Stimulation; Protons; Viscera | 2002 |
Inhibition of cAMP accumulation by kappa-receptor activation in isolated iris-ciliary bodies: role of phosphodiesterase and protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alkaloids; Animals; Benzophenanthridines; Ciliary Body; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; In Vitro Techniques; Iris; Naltrexone; Narcotic Antagonists; Phenanthridines; Phorbol 12,13-Dibutyrate; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperidines; Protein Kinase C; Pyrrolidines; Rabbits; Receptors, Opioid, kappa; Rolipram | 2002 |
Phosphorylation of kinase-related protein (telokin) in tonic and phasic smooth muscles.
Topics: Animals; Carotid Arteries; Chickens; Colforsin; Culture Techniques; Gizzard, Avian; Isometric Contraction; Muscle Contraction; Muscle Proteins; Muscle Relaxation; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Peptide Fragments; Peptide Mapping; Peptides; Phorbol 12,13-Dibutyrate; Phosphorylation; Potassium Chloride; Time Factors | 2001 |
Dual regulation of cardiac Na+-K+ pumps and CFTR Cl- channels by protein kinases A and C.
Topics: Alkaloids; Animals; Benzophenanthridines; Cardiac Glycosides; Cell Membrane; Cell Separation; Chloride Channels; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Activators; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Myocardium; Phenanthridines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptor Cross-Talk; Sodium-Potassium-Exchanging ATPase | 2002 |
Muscarinic receptors couple to modulation of nicotinic ACh receptor desensitization in myenteric neurons.
Topics: Acetylcholine; Animals; Bethanechol; Carcinogens; Cells, Cultured; Colforsin; Guinea Pigs; Membrane Potentials; Muscarinic Agonists; Myenteric Plexus; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Receptors, Muscarinic; Receptors, Nicotinic; Signal Transduction | 2003 |
Adenosine inhibits GABAergic and glycinergic transmission in adult rat substantia gelatinosa neurons.
Topics: 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Colforsin; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Neurons; Pain; Phorbol 12,13-Dibutyrate; Potassium Channel Blockers; Potassium Channels; Rats; Substantia Gelatinosa; Synaptic Transmission | 2004 |
Novel phosphospecific antibodies for monitoring phosphorylation of proteins encoded by the myosin light chain kinase genetic locus.
Topics: Amino Acid Sequence; Animals; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Male; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Kinase; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phosphorylation; Rats; Sequence Homology, Amino Acid; Serine; Signal Transduction | 2004 |
Atypical protein kinase C is a novel mediator of dopamine-enhanced firing in nucleus accumbens neurons.
Topics: Action Potentials; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dopamine; Enzyme Activation; Estrenes; In Vitro Techniques; Indoles; Isoenzymes; Male; Maleimides; Neurons; Nucleus Accumbens; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Type C Phospholipases | 2005 |
Sequential phosphorylation mediates receptor- and kinase-induced inhibition of TREK-1 background potassium channels.
Topics: Alanine; Animals; Aspartic Acid; Binding Sites; Blotting, Western; Cell Line; Cell Membrane; Cloning, Molecular; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Humans; Indoles; Maleimides; Mice; Models, Biological; Mutagenesis, Site-Directed; Mutation; Orexin Receptors; Phorbol 12,13-Dibutyrate; Phosphorylation; Potassium; Potassium Channels; Potassium Channels, Tandem Pore Domain; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Receptors, Thyrotropin-Releasing Hormone; Recombinant Proteins; Serine; Time Factors; Transfection | 2005 |
Cyclic AMP-dependent protein kinase A and protein kinase C phosphorylate alpha4beta2 nicotinic receptor subunits at distinct stages of receptor formation and maturation.
Topics: Acetylcholine; Analysis of Variance; Antibodies; Autoradiography; Biotinylation; Cell Line, Transformed; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Enzyme Inhibitors; Humans; Immunoprecipitation; Indoles; Membrane Potentials; Models, Biological; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Interaction Mapping; Protein Kinase C; Receptors, Nicotinic; Serine; Time Factors; Transfection | 2009 |
Ecstasy and methamphetamine elicit action potential bursts via different mechanisms in a central snail neuron.
Topics: Action Potentials; Adrenergic Agents; Animals; Biophysics; Calcium; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Ganglia, Invertebrate; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Potassium Channel Blockers; Snails; Tetraethylammonium | 2010 |
Cyclin D1 and cyclin D3 show divergent responses to distinct mitogenic stimulation.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Cyclin D3; Cyclin-Dependent Kinase 4; Enzyme Activation; Enzyme Activators; Fibroblasts; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mitogen-Activated Protein Kinases; Mitogens; Mitosis; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Signal Transduction; Sirolimus; Swiss 3T3 Cells; Time Factors; TOR Serine-Threonine Kinases; Transfection | 2010 |
Rapid activation of dormant presynaptic terminals by phorbol esters.
Topics: Analysis of Variance; Animals; Animals, Newborn; Calcium; Carbazoles; Carcinogens; Cells, Cultured; Colforsin; Dizocilpine Maleate; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Indoles; Maleimides; Neurons; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Piperidines; Presynaptic Terminals; Rats; Sucrose; Sweetening Agents; Vesicular Glutamate Transport Protein 1 | 2010 |
Nicotine-induced up regulation of α4β2 neuronal nicotinic receptors is mediated by the protein kinase C-dependent phosphorylation of α4 subunits.
Topics: Analysis of Variance; Autoradiography; Cell Line, Transformed; Colforsin; Dose-Response Relationship, Drug; Humans; Nicotine; Nicotinic Agonists; Phorbol 12,13-Dibutyrate; Phosphorus Isotopes; Phosphorylation; Protein Kinase C; Receptors, Nicotinic; Transfection; Up-Regulation | 2010 |
Role of phospholemman phosphorylation sites in mediating kinase-dependent regulation of the Na+-K+-ATPase.
Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; HeLa Cells; Humans; Membrane Proteins; Myocytes, Cardiac; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Sodium; Sodium-Potassium-Exchanging ATPase | 2010 |
Activation characteristics of transient receptor potential ankyrin 1 and its role in nociception.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Allyl Compounds; Animals; Ankyrins; Behavior, Animal; Calcium; Calcium Channels; Capsaicin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophysiological Phenomena; Excitatory Postsynaptic Potentials; Ganglia, Spinal; Hydrogen-Ion Concentration; Hyperalgesia; Inhibitory Postsynaptic Potentials; Ion Channel Gating; Isocyanates; Maleimides; Membrane Potentials; Mice; Mice, Inbred Strains; Mice, Knockout; Miniature Postsynaptic Potentials; Neurons; Nociception; Nociceptive Pain; Oocytes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spermine; Synaptic Transmission; Tachyphylaxis; Transient Receptor Potential Channels; Trigeminal Caudal Nucleus; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels; Xenopus laevis | 2011 |
Role of protein kinase C-α in hypertonicity-stimulated urea permeability in mouse inner medullary collecting ducts.
Topics: Animals; Biological Transport; Colforsin; Kidney Medulla; Kidney Tubules, Collecting; Mice; Mice, Knockout; Permeability; Phorbol 12,13-Dibutyrate; Protein Kinase C-alpha; Saline Solution, Hypertonic; Urea; Vasopressins | 2013 |