phorbol 12,13-dibutyrate has been researched along with carbachol in 107 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (27.10) | 18.7374 |
| 1990's | 63 (58.88) | 18.2507 |
| 2000's | 11 (10.28) | 29.6817 |
| 2010's | 4 (3.74) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kahan, C; Meloche, S; Pouysségur, J; Seuwen, K | 1 |
| Obara, K; Usuki, T; Yabu, H | 1 |
| McKenzie, FR; Pouysségur, J; Seuwen, K | 1 |
| Izawa, T; Komabayashi, T; Noguchi, M; Sawada, H; Suda, K; Tsuboi, M | 1 |
| Buxbaum, JD; Chen, HI; Gandy, SE; Greengard, P; Jaffe, EA; Oishi, M; Pinkas-Kramarski, R | 1 |
| Nezu, E; Yoshimura, K | 1 |
| Ikeda, K; Machida, J; Nishi, K; Sakiyama, H; Ueda, S; Yoshida, M | 1 |
| Fukaya, Y; Shiraiwa, Y; Yamaguchi, O; Yokota, T; Yoshimura, Y | 1 |
| Raufman, JP | 1 |
| Higgs, NB; Tonge, A; Turnberg, LA; Warhurst, G | 1 |
| Lowe, VC; Noronha-Blob, L | 1 |
| Nahorski, SR; Wojcikiewicz, RJ | 1 |
| Bockaert, J; Manzoni, OJ; Prezeau, L | 1 |
| Blanchard, LM; Larose, L; Morisset, J; Paquette, B | 1 |
| Daniele, E; Govoni, S; Lograno, MD; Trabucchi, M | 1 |
| Hai, CM; Szeto, B | 1 |
| Carmena, MJ; García-Paramio, MP; Prieto, JC | 1 |
| Cubeddu, LX; Diliberto, P; Hoffmann, IS; Lovemberg, T; Talmaciu, RK | 1 |
| Bredt, DS; Donowitz, M; Homaidan, F; Reinlib, L; Sharp, GW; Watson, A; Zahniser, D | 1 |
| Cohen, ML; Lucaites, VL; Mendelsohn, LG; Secrest, RJ | 1 |
| Fermum, R; Kosche, D; Möritz, KU | 1 |
| el-Fakahany, EE; Lai, WS; Rogers, TB | 1 |
| Hartmann, T; Kahan, C; Pouyssegur, J; Seuwen, K | 1 |
| Fredholm, BB | 1 |
| Bilder, GE; Merkel, LA; Perrone, MH; Rivera, LM | 1 |
| Hsu, LC; Kamm, KE; Stull, JT; Tansey, MG | 1 |
| Merritt, JE; Rubin, RP | 1 |
| Ishizuka, T; Ito, Y; Kajita, K; Miura, K; Nagao, S; Nagata, K; Nozawa, Y | 1 |
| McKinney, JS; Rubin, RP | 1 |
| Dandona, P; Jeremy, JY | 1 |
| Chuang, DM; Dillon-Carter, O | 1 |
| Ellis, J; Hendley, DD; Lenox, RH; Weiss, S | 1 |
| Sasaguri, T; Watson, SP | 1 |
| Hsu, LC; Kamm, KE; Kubota, Y; Stull, JT | 1 |
| Baba, K; Baron, CB; Coburn, RF | 1 |
| Brown, JH; Trilivas, I | 1 |
| Ellis, J; Hendley, D; Lenox, RH | 1 |
| Chiba, T; Fujita, T; Hishikawa, R; Inui, T; Kadowaki, S; Kawazu, S; Yamaguchi, A; Yamatani, T | 1 |
| Fondacaro, JD | 1 |
| Florijn, WJ; Versteeg, DH | 1 |
| Janowsky, A; Labarca, R; Paul, SM | 1 |
| Canonico, PL; Catania, MV; Favit, A; Nicoletti, F | 1 |
| Johnson, BG; Schoepp, DD | 1 |
| Chuang, DM | 1 |
| Abdel-Latif, AA; Akhtar, RA; Howe, PH; Naderi, S | 1 |
| Dumont, JE; Erneux, C; Graff, I; Laurent, E; Mockel, J | 1 |
| el-Fakahany, EE; Lai, WS | 2 |
| Hunter, DD; Liles, WC; Meier, KE; Nathanson, NM | 1 |
| Gerthoffer, WT | 1 |
| Andrade, R; Madison, DV; Malenka, RC; Nicoll, RA | 1 |
| Burlingame, SM; Lester, R; Mitchell, PA; Potter, GD; Schmidt, KL | 1 |
| Merritt, JE; Putney, JW; Rubin, RP; Taylor, CW | 1 |
| Janowsky, A; Labarca, R; Patel, J; Paul, SM | 1 |
| Chapman, DA; Godfrey, PP; Putney, JW; Rubin, RP | 1 |
| Pappano, AJ; Webb, WW | 1 |
| Bennett, JL; Blair, KL; Pax, RA | 2 |
| Raymond, MN; Robin, P; Rossignol, B | 1 |
| Satoh, H; Sperelakis, N | 1 |
| Blanc, E; Recasens, M; Vignes, M | 1 |
| Ambrosini, A; Racagni, G | 1 |
| Chopra, LC; Twort, CH; Ward, JP | 1 |
| Dartt, DA; Dicker, DM; Hodges, RR; Zoukhri, D | 1 |
| Nakashio, A; Shibata, S; Ueki, S; Watanabe, S | 1 |
| Green, MA; Li, PP; Sibony, D; Warsh, JJ | 1 |
| Bajnath, RB; De Jonge, HR; Groot, JA; van den Berghe, N | 1 |
| Buxton, IL; Zhang, L | 1 |
| Castro, E; Delicado, EG; Miras-Portugal, MT; Sen, RP | 1 |
| Corso, M; Horwitz, J; Passarello, B | 1 |
| Benz, D; Möller, K; Perrin, D; Söling, HD | 1 |
| Challiss, RA; Nahorski, SR; Stuart, JA; Willars, GB | 1 |
| Gong, MC; Jensen, PE; Somlyo, AP; Somlyo, AV | 1 |
| Mills, J; Reiner, PB | 1 |
| Turner, NA; Vaughan, PF; Walker, JH | 1 |
| Higashi, T; Honda, T; Kimura, T; Konishi, J | 1 |
| Satoh, H | 1 |
| Abdel-Latif, AA; Akhtar, RA; Wang, XL | 1 |
| Ahn, SC; Kim, KW; Kim, SJ; Kim, YC; So, I | 1 |
| Dartt, DA; Hodges, RR; Willert, S; Zoukhri, D | 1 |
| Loikkanen, J; Naarala, J; Savolainen, K; Tervo, P | 1 |
| Ahn, SC; Kim, KW; Kim, SJ; So, I | 1 |
| Dobashi, K; Horie, T; Iizuka, K; Mori, M; Nakazawa, T; Suzuki, H; Yoshii, A | 1 |
| Daniele, E; Lograno, MD; Villani, G | 1 |
| Almazan, G; Larocca, JN | 1 |
| Bennett, DJ; Beuerman, RW; Meneray, MA; Nguyen, DH | 1 |
| Buxbaum, JD; Czernik, AJ; Desdouits, F; Desdouits-Magnen, J; Greengard, P; Nairn, AC; Saltiel, AR; Syu, LJ; Takeda, S | 1 |
| Dartt, DA; Hodges, RR; Sergheraert, C; Zoukhri, D | 1 |
| Harbon, S; Lajat, S; Tanfin, Z | 1 |
| Abdel-Latif, AA; Ding, KH; Latimer, AJ | 1 |
| Govoni, S; Racchi, M; Sironi, M; Solano, DC | 1 |
| Alroy, G; Su, H; Yaari, Y | 1 |
| Murakami, M; Segawa, A; Yoshimura, K | 1 |
| Costa, LG; Guizzetti, M | 1 |
| Laychock, SG; Tian, Y | 1 |
| Dobashi, K; Endou, K; Iizuka, K; Ishizuka, T; Mori, M; Nakazawa, T; Tsukagoshi, H; Yoshii, A | 1 |
| Fujita, A; Hata, F; Hirayama, N; Kitayama, M; Kushida, M; Takeuchi, T | 1 |
| Cuadra, AE; El-Fakahany, EE | 1 |
| Kamata, K; Kasuya, Y; Kobayashi, T; Matsumoto, T; Nishiyama, M | 1 |
| Eddinger, TJ; Schiebout, JD; Swartz, DR | 1 |
| Furness, JB; Poole, DP | 1 |
| Azuma, YT; Hata, F; Nakajima, H; Takeuchi, T | 1 |
| Gao, TW; Liao, WJ; Lv, YJ; Wang, H; Wang, ZR; Yu, YQ; Zhang, YG | 1 |
| Babu, GJ; Eddinger, TJ; Huang, Q; Periasamy, M | 1 |
| Anhê, GF; Antunes, E; Calixto, MC; De Nucci, G; Grant, AD; Leiria, LO; Lintomen, L; Mónica, FZ; Sollon, C; Zanesco, A | 1 |
| Eddinger, TJ; Hermanson, ME; Zhang, Y | 1 |
| Chiba, Y; Ikebe, M; Kai, Y; Sakai, H; Sato, K | 1 |
1 review(s) available for phorbol 12,13-dibutyrate and carbachol
| Article | Year |
|---|---|
Intestinal ion transport and diarrheal disease.
Topics: Acid-Base Equilibrium; Adrenergic alpha-Agonists; Animals; Arachidonic Acids; Carbachol; Chlorides; Cholera Toxin; Cyclic AMP; Cyclic GMP; Diarrhea; Electric Stimulation; Electrolytes; Hydroxyeicosatetraenoic Acids; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Leukotrienes; Models, Biological; Narcotics; Phenothiazines; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Protein Kinase C; Receptors, Cholinergic; Receptors, Muscarinic; Renin-Angiotensin System; Sodium; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate | 1986 |
106 other study(ies) available for phorbol 12,13-dibutyrate and carbachol
| Article | Year |
|---|---|
Coordinate, biphasic activation of p44 mitogen-activated protein kinase and S6 kinase by growth factors in hamster fibroblasts. Evidence for thrombin-induced signals different from phosphoinositide turnover and adenylylcyclase inhibition.
Topics: Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cricetinae; Cricetulus; Enzyme Activation; Fibroblast Growth Factor 2; Fibroblasts; Humans; Kinetics; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinases; Ribosomal Protein S6 Kinases; Thrombin; Virulence Factors, Bordetella | 1992 |
Calcium and potassium channel regulation by protein phosphorylation in smooth muscle cells of guinea pig taenia coli.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Atropine; Calcium Channels; Carbachol; Colon; Guinea Pigs; In Vitro Techniques; Isoquinolines; Marine Toxins; Membrane Potentials; Models, Biological; Muscle, Smooth; Nifedipine; Oxazoles; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Piperazines; Potassium Channels; Protein Kinase C | 1992 |
Stimulation of phosphatidylcholine breakdown by thrombin and carbachol but not by tyrosine kinase receptor ligands in cells transfected with M1 muscarinic receptors. Rapid desensitization of phosphocholine-specific (PC) phospholipase D but sustained activ
Topics: Animals; Carbachol; Cell Line; Choline; Cricetinae; Cricetulus; Diglycerides; Growth Substances; Humans; Hydrolysis; Kinetics; Ligands; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phospholipase D; Phosphoric Diester Hydrolases; Phosphorylcholine; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, Muscarinic; Recombinant Proteins; Signal Transduction; Thrombin; Transfection; Type C Phospholipases | 1992 |
Phorbol ester alters carbachol-stimulated diacylglycerol formation in parotid acinar cells through the hydrolysis of phosphoinositides and phosphatidylcholine.
Topics: Animals; Carbachol; Diglycerides; Hydrolysis; Male; Parotid Gland; Phorbol 12,13-Dibutyrate; Phosphatidylcholines; Phosphatidylinositols; Rats; Rats, Wistar | 1992 |
Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor.
Topics: Acetylcholine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Cell Line; Cells, Cultured; Chloroquine; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Interleukin-1; Kinetics; Parasympathomimetics; PC12 Cells; Phorbol 12,13-Dibutyrate; Protein Kinase C; Recombinant Proteins; Umbilical Veins | 1992 |
Interaction between the calcium and cyclic AMP messenger systems in perifused rat parotid acinar cells. Possible mechanism for potentiation of amylase secretion.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Calcium; Carbachol; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Isoproterenol; Male; Parotid Gland; Perfusion; Phorbol 12,13-Dibutyrate; Phosphorylation; Rats; Rats, Inbred Strains; Second Messenger Systems; Sulfonamides; Trifluoperazine | 1992 |
Effects of phorbol ester on lower urinary tract smooth muscles in rabbits.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbachol; Drug Interactions; Female; Isoquinolines; Muscle Contraction; Muscle, Smooth; Phenylephrine; Phorbol 12,13-Dibutyrate; Piperazines; Potassium Chloride; Protein Kinase Inhibitors; Rabbits; Urethra; Urinary Bladder | 1992 |
Calcium ion-independent contraction of bladder smooth muscle.
Topics: Animals; Caffeine; Calcium; Carbachol; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Rabbits; Urinary Bladder | 1992 |
Actions of phorbol esters on levels of cAMP in cholera toxin-treated chief cells from guinea pig stomach.
Topics: Animals; Calcimycin; Calmodulin; Carbachol; Cholera Toxin; Gastric Mucosa; Guinea Pigs; Imidazoles; In Vitro Techniques; Kinetics; Male; Phorbol 12,13-Dibutyrate; Phorbols; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate | 1992 |
Stimulatory and inhibitory actions of carbachol on chloride secretory responses in human colonic cell line T84.
Topics: Calcimycin; Carbachol; Cell Line; Chlorides; Colon; Cyclic AMP; Dinoprostone; Humans; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Virulence Factors, Bordetella | 1991 |
Effect of extracellular Ca2+ on cholinergic, KCl and phorbol ester-mediated phosphoinositide turnover and guinea pig urinary bladder contraction.
Topics: Animals; Calcium; Carbachol; Enzyme Activation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Potassium Chloride; Protein Kinase C; Receptors, Muscarinic; Urinary Bladder | 1991 |
Chronic muscarinic stimulation of SH-SY5Y neuroblastoma cells suppresses inositol 1,4,5-trisphosphate action. Parallel inhibition of inositol 1,4,5-trisphosphate-induced Ca2+ mobilization and inositol 1,4,5-trisphosphate binding.
Topics: Calcium; Calcium Channels; Carbachol; Cell Line; Cell Membrane; Cell Membrane Permeability; Colforsin; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Kinetics; Neuroblastoma; Phorbol 12,13-Dibutyrate; Plant Extracts; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Terpenes; Thapsigargin; Tretinoin | 1991 |
beta-N-methylamino-L-alanine is a low-affinity agonist of metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids, Diamino; Animals; Carbachol; Cells, Cultured; Corpus Striatum; Cyanobacteria Toxins; Cycloleucine; Dizocilpine Maleate; Embryo, Mammalian; Glutamates; Inositol; Inositol Phosphates; Kinetics; Mice; Neurons; Neurotoxins; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Carbamylcholine and phorbol esters desensitize muscarinic receptors by different mechanisms in rat pancreatic acini.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amylases; Animals; Calcimycin; Carbachol; Dose-Response Relationship, Drug; Down-Regulation; Gallic Acid; Isoquinolines; Male; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Secretory Rate; Tetradecanoylphorbol Acetate | 1990 |
Evidence for protein kinase C modulation of the ciliary muscle response to carbachol and desensitization.
Topics: Alkaloids; Animals; Carbachol; Cattle; Ciliary Body; Diglycerides; Dinoprost; Enzyme Activation; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Staurosporine; Substance P | 1991 |
Agonist-induced myosin phosphorylation during isometric contraction and unloaded shortening in airway smooth muscle.
Topics: Animals; Carbachol; Cattle; Electric Stimulation; Electrophysiology; Histamine; In Vitro Techniques; Isometric Contraction; Muscle, Smooth; Myosins; Phorbol 12,13-Dibutyrate; Phosphorylation; Potassium; Time Factors; Trachea | 1992 |
Up-modulation of phorbol dibutyrate receptors by carbachol and arachidonic acid in rat prostatic epithelial cells.
Topics: Animals; Arachidonic Acids; Binding, Competitive; Caenorhabditis elegans Proteins; Calcium; Carbachol; Carrier Proteins; Epithelial Cells; Epithelium; Male; Phorbol 12,13-Dibutyrate; Prostate; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Drug; Up-Regulation | 1991 |
Carbachol-phorbol ester interactions at muscarinic receptors modulating dopamine release from rabbit striatal slices.
Topics: Animals; Atropine; Brain Chemistry; Carbachol; Corpus Striatum; Dopamine; Hexamethonium Compounds; In Vitro Techniques; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rabbits; Receptors, Muscarinic | 1991 |
Uncoupling of phospholipase C from receptor regulation of [Ca2+]i in T84 colonic cells by prolonged exposure to phorbol dibutyrate.
Topics: Animals; Calcium; Carbachol; Cell Line; Colon; Fluorescent Dyes; Fura-2; Histamine; Inositol 1,4,5-Trisphosphate; Phorbol 12,13-Dibutyrate; Quinuclidinyl Benzilate; Rats; Type C Phospholipases | 1991 |
Protein kinase C translocation in rat stomach fundus: effects of serotonin, carbamylcholine and phorbol dibutyrate.
Topics: Alkaloids; Animals; Carbachol; Gastric Fundus; Male; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred Strains; Serotonin; Staurosporine | 1991 |
Membrane-associated signal transduction modulates contractile responses to Ca2+ in saponin-skinned coronary smooth muscle.
Topics: Aluminum; Animals; Calcium; Carbachol; Cattle; Coronary Vessels; Female; Fluorides; Guanylyl Imidodiphosphate; Histamine; In Vitro Techniques; Male; Membranes; Permeability; Phorbol 12,13-Dibutyrate; Saponins; Signal Transduction; Swine; Vasoconstriction | 1991 |
Protein kinase C is involved in desensitization of muscarinic receptors induced by phorbol esters but not by receptor agonists.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Carbachol; Cyclic GMP; Down-Regulation; Isoquinolines; Mice; N-Methylscopolamine; Neuroblastoma; Parasympathomimetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Receptors, Muscarinic; Scopolamine Derivatives; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Strong and persistent activation of inositol lipid breakdown induces early mitogenic events but not Go to S phase progression in hamster fibroblasts. Comparison of thrombin and carbachol action in cells expressing M1 muscarinic acetylcholine receptors.
Topics: Adenylate Cyclase Toxin; Animals; Atropine; Calcium; Carbachol; Cell Cycle; Cell Line; Clone Cells; Cricetinae; Cricetulus; DNA Replication; Fibroblasts; Inositol; Inositol Phosphates; Kinetics; Lung; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Pirenzepine; Proto-Oncogenes; Receptors, Muscarinic; Resting Phase, Cell Cycle; S Phase; Thrombin; Transfection; Virulence Factors, Bordetella | 1990 |
Adenosine A1-receptor-mediated inhibition of evoked acetylcholine release in the rat hippocampus does not depend on protein kinase C.
Topics: Acetylcholine; Adenosine; Animals; Arachidonate 5-Lipoxygenase; Carbachol; Electric Stimulation; Ethylmaleimide; Hippocampus; Male; Masoprocol; Nifedipine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Purinergic | 1990 |
Differential alteration of vascular reactivity in rabbit aorta with modest elevation of serum cholesterol.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Carbachol; Cholesterol; Cholesterol, Dietary; Dinoprost; Hypercholesterolemia; In Vitro Techniques; Isoproterenol; Male; Nitroprusside; Norepinephrine; Phorbol 12,13-Dibutyrate; Rabbits; Serotonin; Time Factors; Vasoconstriction; Vasodilation | 1990 |
Myosin light chain kinase phosphorylation in tracheal smooth muscle.
Topics: Animals; Autoradiography; Carbachol; Cattle; Electrophoresis, Gel, Two-Dimensional; In Vitro Techniques; Isometric Contraction; Isoproterenol; Kinetics; Muscle, Smooth; Myosin-Light-Chain Kinase; Phorbol 12,13-Dibutyrate; Phosphopeptides; Phosphorus Radioisotopes; Phosphorylation; Potassium Chloride; Protein Kinase C; Trachea; Trypsin | 1990 |
Pancreatic amylase secretion and cytoplasmic free calcium. Effects of ionomycin, phorbol dibutyrate and diacylglycerols alone and in combination.
Topics: Amylases; Animals; Calcium; Carbachol; Ceruletide; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Ethers; Ionomycin; Ionophores; Male; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Rats, Inbred Strains | 1985 |
Redistribution of protein kinase C in pancreatic acinar cells stimulated with caerulein or carbachol.
Topics: Amylases; Animals; Caenorhabditis elegans Proteins; Carbachol; Carcinogens; Carrier Proteins; Cell Fractionation; Cell Membrane; Ceruletide; Cytosol; In Vitro Techniques; Kinetics; Male; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, Immunologic; Subcellular Fractions | 1987 |
Enhancement of cyclic AMP modulated salivary amylase secretion by protein kinase C activators.
Topics: Amylases; Animals; Carbachol; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Isoproterenol; Male; Parotid Gland; Phorbol 12,13-Dibutyrate; Rats; Rats, Inbred Strains; Saliva | 1988 |
Effect of endothelium removal on stimulatory and inhibitory modulation of rat aortic prostacyclin synthesis.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Aorta; Carbachol; Endothelium, Vascular; Epinephrine; Epoprostenol; In Vitro Techniques; Male; Nifedipine; Nitroprusside; Norepinephrine; Phorbol 12,13-Dibutyrate; Prazosin; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Sodium Fluoride; Substance P; Yohimbine | 1989 |
Homologous desensitization of muscarinic cholinergic, histaminergic, adrenergic, and serotonergic receptors coupled to phospholipase C in cerebellar granule cells.
Topics: Animals; Carbachol; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Histamine; Inositol Phosphates; Norepinephrine; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Histamine; Receptors, Muscarinic; Receptors, Serotonin; Serotonin; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1989 |
Translocation and activation of protein kinase C in striatal neurons in primary culture: relationship to phorbol dibutyrate actions on the inositol phosphate generating system and neurotransmitter release.
Topics: Animals; Biological Transport; Carbachol; Cell Membrane; Cells, Cultured; Corpus Striatum; Cytosol; Enzyme Activation; gamma-Aminobutyric Acid; Inositol Phosphates; Kinetics; Mice; Neurons; Neurotransmitter Agents; Phorbol 12,13-Dibutyrate; Potassium Chloride; Protein Kinase C; Sugar Phosphates | 1989 |
Protein kinase C regulates the tonic but not the phasic component of contraction in guinea-pig ileum.
Topics: Animals; Carbachol; Down-Regulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Inositol Phosphates; Male; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C | 1989 |
Phosphorylation of smooth muscle myosin heavy and light chains. Effects of phorbol dibutyrate and agonists.
Topics: Animals; Carbachol; Cattle; Cells, Cultured; Electrophoresis, Gel, Two-Dimensional; In Vitro Techniques; Isoproterenol; Kinetics; Muscle Contraction; Muscle, Smooth; Myosin Subfragments; Peptide Mapping; Phorbol 12,13-Dibutyrate; Phosphopeptides; Phosphorylation; Trachea | 1989 |
Phorbol ester effects on coupling mechanisms during cholinergic contraction of swine tracheal smooth muscle.
Topics: Amiloride; Animals; Carbachol; In Vitro Techniques; Inositol Phosphates; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Swine; Trachea; Verapamil | 1989 |
Increases in intracellular Ca2+ regulate the binding of [3H]phorbol 12,13-dibutyrate to intact 1321N1 astrocytoma cells.
Topics: Astrocytoma; Binding Sites; Bradykinin; Calcium; Carbachol; Cell Membrane; Cytosol; Diglycerides; Ethers; Histamine; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Kinetics; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; Tumor Cells, Cultured | 1989 |
Desensitization of muscarinic receptor-coupled phosphoinositide hydrolysis in rat hippocampus: comparisons with the alpha 1-adrenergic response.
Topics: Animals; Atropine; Carbachol; Chlorides; Epinephrine; Hippocampus; Hydrolysis; Kinetics; Lithium; Lithium Chloride; Male; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Muscarinic | 1988 |
Dual action of protein kinase C activation in the regulation of insulin release by muscarinic agonist from rat insulinoma cell line (RINr).
Topics: Adenoma, Islet Cell; Animals; Carbachol; Cell Membrane; Enzyme Activation; Inositol Phosphates; Insulin; Insulin Secretion; Insulinoma; Pancreatic Neoplasms; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Receptors, Muscarinic; Scopolamine; Tumor Cells, Cultured | 1988 |
Phorbol 12,13-dibutyrate enhances electrically stimulated neuromessenger release from rat dorsal hippocampal slices in vitro.
Topics: Acetylcholine; Animals; Carbachol; Clonidine; Electric Stimulation; Enkephalin, Leucine; Hippocampus; In Vitro Techniques; Male; Neurotransmitter Agents; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Rats, Inbred Strains; Serotonin; Yohimbine | 1987 |
Neurotransmitter-stimulated inositol phosphate accumulation in hippocampal slices.
Topics: Animals; Carbachol; Hippocampus; In Vitro Techniques; Inositol; Inositol Phosphates; Kinetics; Manganese; Neurotransmitter Agents; Phorbol 12,13-Dibutyrate; Phorbol Esters; Radioisotope Dilution Technique; Sugar Phosphates; Tetradecanoylphorbol Acetate; Tritium | 1987 |
Phorbol esters attenuate glutamate-stimulated inositol phospholipid hydrolysis in neuronal cultures.
Topics: Animals; Aspartic Acid; Carbachol; Cerebellum; Diglycerides; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; N-Methylaspartate; Neurons; Oxadiazoles; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Sphingosine; Tetradecanoylphorbol Acetate | 1988 |
Selective inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in the rat hippocampus by activation of protein kinase C.
Topics: Alkaloids; Amino Acids; Animals; Carbachol; Enzyme Activation; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Ibotenic Acid; Male; Norepinephrine; Oxadiazoles; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Quisqualic Acid; Rats; Rats, Inbred Strains; Staurosporine | 1988 |
Carbachol-induced accumulation of inositol-1-phosphate in neurohybridoma NCB-20 cells: effects of lithium and phorbol esters.
Topics: Animals; Atropine; Benzodiazepinones; Brain; Carbachol; Cell Line; Chlorides; Cricetinae; Cricetulus; Embryo, Mammalian; Hybridomas; Inositol Phosphates; Lithium; Lithium Chloride; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pirenzepine; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1986 |
Correlative studies on the effect of carbachol on myo-inositol trisphosphate accumulation, myosin light chain phosphorylation and contraction in sphincter smooth muscle of rabbit iris.
Topics: Animals; Atropine; Calcium; Carbachol; Ethers; Female; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Iris; Male; Membranes; Muscle Contraction; Muscle, Smooth; Myosins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphorylation; Rabbits; Sugar Phosphates; Temperature; Time Factors | 1986 |
Carbachol and sodium fluoride, but not TSH, stimulate the generation of inositol phosphates in the dog thyroid.
Topics: Animals; Atropine; Carbachol; Chlorides; Dogs; In Vitro Techniques; Inositol; Inositol Phosphates; Kinetics; Lithium; Lithium Chloride; Phorbol 12,13-Dibutyrate; Phorbol Esters; Sodium Fluoride; Sugar Phosphates; Thyroid Gland; Thyrotropin; Tritium | 1987 |
Phorbol ester-induced inhibition of cyclic GMP formation mediated by muscarinic receptors in murine neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Carbachol; Cell Line; Cyclic GMP; Dose-Response Relationship, Drug; Histamine; Isoquinolines; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Piperazines; Receptors, Muscarinic; Tetradecanoylphorbol Acetate | 1987 |
Activation of protein kinase C induces rapid internalization and subsequent degradation of muscarinic acetylcholine receptors in neuroblastoma cells.
Topics: Animals; Calcimycin; Calcium; Carbachol; Cell Line; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Kinetics; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylserines; Protein Kinase C; Quinuclidinyl Benzilate; Receptors, Cholinergic; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Dissociation of myosin phosphorylation and active tension during muscarinic stimulation of tracheal smooth muscle.
Topics: Atropine; Calcium; Calcium Chloride; Carbachol; Dose-Response Relationship, Drug; Egtazic Acid; Muscle Contraction; Muscle, Smooth; Myosins; Nifedipine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Potassium; Serotonin; Tetradecanoylphorbol Acetate; Trachea | 1987 |
Regulation of [3H]phorbol-12,13-dibutyrate binding sites in mouse neuroblastoma cells: simultaneous down-regulation by phorbol esters and desensitization of their inhibition of muscarinic receptor function.
Topics: Animals; Binding Sites; Carbachol; Clone Cells; Enzyme Activation; Kinetics; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Muscarinic | 1988 |
Phorbol esters mimic some cholinergic actions in hippocampal pyramidal neurons.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Enzyme Activation; Evoked Potentials, Somatosensory; Hippocampus; Neurons; Parasympathomimetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Pyramidal Tracts; Rats; Receptors, Muscarinic; Tetraethylammonium Compounds; Tetrodotoxin | 1986 |
Taurodeoxycholate and the developing rabbit distal colon: absence of secretory effect.
Topics: Animals; Bradykinin; Carbachol; Colon; Deoxycholic Acid; Epithelium; Female; Male; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rabbits; Reference Values; Serotonin; Taurodeoxycholic Acid; Theophylline | 1987 |
Isomers of inositol trisphosphate in exocrine pancreas.
Topics: Animals; Calcium; Carbachol; Ceruletide; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isomerism; Male; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Rats, Inbred Strains; Sugar Phosphates | 1986 |
Phorbol esters inhibit agonist-induced [3H] inositol-1-phosphate accumulation in rat hippocampal slices.
Topics: Animals; Caenorhabditis elegans Proteins; Carbachol; Carcinogens; Carrier Proteins; Hippocampus; Inositol; Inositol Phosphates; Male; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Rats; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1984 |
Secretagogue-induced formation of inositol phosphates in rat exocrine pancreas. Implications for a messenger role for inositol trisphosphate.
Topics: Animals; Carbachol; Ceruletide; Ethers; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Sugar Phosphates | 1984 |
Muscarinic agonist-induced positive inotropic response in chick atria.
Topics: Animals; Calcium; Carbachol; Cardiotonic Agents; Chickens; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Muscarinic Agonists; Myocardial Contraction; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Sarcoplasmic Reticulum; Sodium; Virulence Factors, Bordetella | 1995 |
Serotonin and acetylcholine: further analysis of praziquantel-induced contraction of magnesium-paralysed Schistosoma mansoni.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Amifampridine; Animals; Arecoline; Carbachol; Colforsin; Dose-Response Relationship, Drug; In Vitro Techniques; Ions; Magnesium; Male; Muscle Contraction; Paralysis; Phorbol 12,13-Dibutyrate; Praziquantel; Schistosoma mansoni; Serotonin | 1993 |
Effect of microtubule network disturbance by nocodazole and docetaxel (Taxotere) on protein secretion in rat extraorbital lacrimal and parotid glands.
Topics: Animals; Bucladesine; Calcimycin; Carbachol; Docetaxel; Dose-Response Relationship, Drug; Epinephrine; Fluorescent Antibody Technique; Galactose; Glycoproteins; Isoproterenol; Lacrimal Apparatus; Male; Microtubules; Nocodazole; Paclitaxel; Parotid Gland; Phorbol 12,13-Dibutyrate; Rats; Rats, Sprague-Dawley; Taxoids | 1995 |
Modulation of L-type Ca2+ current by isoprenaline, carbachol and phorbol ester in cultured rat aortic vascular smooth muscle (A7r5) cells.
Topics: Animals; Aorta; Calcium; Calcium Channels; Carbachol; Cells, Cultured; Isoproterenol; Membrane Potentials; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Stimulation, Chemical | 1995 |
Protein kinase C differently regulates quisqualate- and 1S,3R-trans aminocyclopentane dicarboxylate-induced phosphoinositide hydrolysis during in vitro development of hippocampal neurons.
Topics: Alkaloids; Animals; Carbachol; Cells, Cultured; Cycloleucine; Enzyme Activation; Hippocampus; Hydrolysis; Neurons; Neurotoxins; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Quisqualic Acid; Rats; Staurosporine | 1995 |
Glutamate receptor-induced cyclic GMP formation in primary cultures of mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Fetus; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Mesencephalon; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, Glutamate | 1993 |
Differences in sensitivity to the specific protein kinase C inhibitor Ro31-8220 between small and large bronchioles of the rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bronchi; Bronchoconstriction; Carbachol; In Vitro Techniques; Indoles; Isoquinolines; Male; Maleimides; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Wistar; Serotonin | 1994 |
Role of protein kinase C in cholinergic stimulation of lacrimal gland protein secretion.
Topics: Amino Acid Sequence; Animals; Calcium; Carbachol; Isoenzymes; Lacrimal Apparatus; Male; Molecular Sequence Data; Parasympathomimetics; Peroxidases; Phorbol 12,13-Dibutyrate; Protein Kinase C; Proteins; Rats; Rats, Wistar | 1994 |
Facilitatory effect of phorbol ester on 2-deoxyglucose uptake in rat hippocampal slices.
Topics: Alkaloids; Animals; Carbachol; Carbazoles; Deoxyglucose; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Indole Alkaloids; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Quisqualic Acid; Rats; Rats, Wistar; Staurosporine | 1993 |
Schistosoma mansoni: myogenic characteristics of phorbol ester-induced muscle contraction.
Topics: Acetylcholine; Animals; Cadmium; Calcimycin; Calcium; Calcium Channels; Carbachol; Cell Membrane Permeability; Dose-Response Relationship, Drug; Electromyography; Hydrogen-Ion Concentration; Male; Membrane Potentials; Microelectrodes; Muscle Contraction; Nicardipine; Phorbol 12,13-Dibutyrate; Praziquantel; Protein Kinase C; Schistosoma mansoni; Serotonin; Sodium; Tetradecanoylphorbol Acetate | 1994 |
Lithium modulation of phosphoinositide signaling system in rat cortex: selective effect on phorbol ester binding.
Topics: Animals; Caenorhabditis elegans Proteins; Calcium Channels; Carbachol; Carrier Proteins; Cell Membrane; Cerebral Cortex; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kinetics; Lithium Chloride; Male; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, Drug; Signal Transduction; Sodium Fluoride | 1993 |
Activation of ion transport by combined effects of ionomycin, forskolin and phorbol ester on cultured HT-29cl.19A human colonocytes.
Topics: Biological Transport; Calcium; Carbachol; Chloride Channels; Colforsin; Colonic Neoplasms; Cyclic AMP; Drug Synergism; Electric Conductivity; Humans; Ionomycin; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C; Tumor Cells, Cultured | 1993 |
Protein kinase regulation of muscarinic receptor signalling in colonic smooth muscle.
Topics: Animals; Binding, Competitive; Carbachol; Colforsin; Colon; Cyclic AMP; Dogs; Female; GTP-Binding Proteins; Male; Membranes; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Protein Kinases; Radioligand Assay; Receptors, Muscarinic; Signal Transduction | 1993 |
Effect of P2Y agonists on adenosine transport in cultured chromaffin cells.
Topics: Adenosine; Adenosine Diphosphate; Adenylyl Imidodiphosphate; Adrenal Medulla; Animals; Biological Transport; Bradykinin; Carbachol; Cattle; Cells, Cultured; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Kinetics; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Purinergic; Thionucleotides | 1993 |
Bradykinin stimulates phospholipase D in PC12 cells by a mechanism which is independent of increases in intracellular Ca2+.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Carbachol; Enzyme Inhibitors; Ethanol; Ionomycin; Ionophores; Neurons; PC12 Cells; Phorbol 12,13-Dibutyrate; Phospholipase D; Rats; Stimulation, Chemical; Terpenes; Thapsigargin | 1995 |
The role of protein kinase C in carbachol-induced and of cAMP-dependent protein kinase in isoproterenol-induced secretion in primary cultured guinea pig parotid acinar cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Amylases; Animals; Calcium; Carbachol; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Exocytosis; Guinea Pigs; Immunoblotting; Isoproterenol; Isoquinolines; Male; Parotid Gland; Phorbol 12,13-Dibutyrate; Piperazines; Protein Binding; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate | 1996 |
Contrasting effects of phorbol ester and agonist-mediated activation of protein kinase C on phosphoinositide and Ca2+ signalling in a human neuroblastoma.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Carbachol; Cell Line; CHO Cells; Cricetinae; Cytosol; Enzyme Activation; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Lithium; N-Methylscopolamine; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Receptor, Muscarinic M3; Receptors, Muscarinic; Recombinant Proteins; Scopolamine Derivatives; Signal Transduction; Terpenes; Thapsigargin; Transfection; Tumor Cells, Cultured | 1996 |
Separate upstream and convergent downstream pathways of G-protein- and phorbol ester-mediated Ca2+ sensitization of myosin light chain phosphorylation in smooth muscle.
Topics: Animals; Calcium; Carbachol; Cell Membrane; Cytosol; Femoral Artery; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ileum; In Vitro Techniques; Isoenzymes; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Myosin Light Chains; Phorbol 12,13-Dibutyrate; Phosphorylation; Portal Vein; Protein Kinase C; Rabbits; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1996 |
Phorbol esters but not the cholinergic agonists oxotremorine-M and carbachol increase release of the amyloid precursor protein in cultured rat cortical neurons.
Topics: Amyloid beta-Protein Precursor; Animals; Atropine; Carbachol; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Muscarinic Agonists; Neurons; Oxotremorine; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate | 1996 |
The effect of down-regulation and long-term inhibition of protein kinase C on noradrenaline secretion in the neuroblastoma cell line SH-SY5Y.
Topics: Calcimycin; Carbachol; Down-Regulation; Enzyme Inhibitors; Humans; Indoles; Maleimides; Neuroblastoma; Norepinephrine; Phorbol 12,13-Dibutyrate; Potassium Chloride; Protein Kinase C; Time Factors; Tumor Cells, Cultured | 1996 |
High concentrations of cholecystokinin octapeptide suppress protein kinase C activity in guinea pig pancreatic acini.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Bombesin; Carbachol; Cricetinae; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Gastrointestinal Agents; In Vitro Techniques; Male; Pancreas; Phorbol 12,13-Dibutyrate; Protein Binding; Protein Kinase C; Sincalide; Tetragastrin | 1996 |
Modulation of Ca(2+)-activated K+ current by isoprenaline, carbachol, and phorbol ester in cultured (and fresh) rat aortic vascular smooth muscle cells.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Calcium; Carbachol; Cell Line; Isoproterenol; Muscarinic Agonists; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Rats | 1996 |
Purification and properties of D-myo-inositol 1,4,5-trisphosphate 3-kinase from bovine iris sphincter smooth muscle: effects of protein phosphorylation in vitro and in intact muscle.
Topics: Animals; Calcium; Calmodulin; Carbachol; Cattle; Chromatography, Affinity; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Polyacrylamide Gel; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Iris; Isoproterenol; Kinetics; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Substrate Specificity | 1995 |
Dual roles of phorbol 12, 13-dibutyrate in the regulation of guinea-pig gastric contraction.
Topics: Animals; Calcium; Carbachol; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Stomach | 1997 |
Immunolocalization of lacrimal gland PKC isoforms. Effect of phorbol esters and cholinergic agonists on their cellular distribution.
Topics: Animals; Blotting, Western; Carbachol; Carcinogens; Cell Fractionation; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique, Indirect; Isoenzymes; Lacrimal Apparatus; Male; Muscarinic Agonists; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar | 1997 |
Cholinergic-induced production of reactive oxygen species in human neuroblastoma cells.
Topics: Biological Transport; Calcium; Carbachol; Humans; Muscarinic Agonists; Neuroblastoma; Phorbol 12,13-Dibutyrate; Protein Kinase C; Quinuclidinyl Benzilate; Reactive Oxygen Species; Tumor Cells, Cultured | 1997 |
Inhibitory effect of phorbol 12,13 dibutyrate on carbachol-activated nonselective cationic current in guinea-pig gastric myocytes.
Topics: Animals; Carbachol; Cations; Electric Conductivity; Gastric Mucosa; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ion Channels; Muscarinic Agonists; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Stomach | 1997 |
Receptor-dependent G protein-mediated Ca2+ sensitization in canine airway smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aluminum; Animals; Bacterial Toxins; Calcium; Calcium-Binding Proteins; Calponins; Carbachol; Cell Membrane Permeability; Dogs; Endothelin-1; Escin; Female; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hemolysin Proteins; Histamine; Isometric Contraction; Male; Microfilament Proteins; Muscle, Smooth; Peptide Fragments; Phorbol 12,13-Dibutyrate; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Muscarinic; Serotonin; Thromboxane A2; Trachea | 1997 |
Effects of phorbol ester on carbachol-induced contraction in bovine ciliary muscle: possible involvement of protein kinase C.
Topics: Animals; Carbachol; Cattle; Ciliary Body; Drug Interactions; Histones; In Vitro Techniques; Muscarinic Agonists; Muscle Contraction; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Receptors, Muscarinic; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1997 |
Acetylcholine agonists stimulate mitogen-activated protein kinase in oligodendrocyte progenitors by muscarinic receptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Atropine; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cells, Cultured; Cholinergic Agents; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Indoles; Maleimides; Mitogen-Activated Protein Kinase 1; Oligodendroglia; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction; Stem Cells; Tetradecanoylphorbol Acetate | 1997 |
Effect of sensory denervation on the structure and physiologic responsiveness of rabbit lacrimal gland.
Topics: Animals; Carbachol; Cells, Cultured; Colforsin; Eye Proteins; Ganglionectomy; Isoproterenol; Lacrimal Apparatus; Male; Phorbol 12,13-Dibutyrate; Rabbits; Sympathomimetics; Trigeminal Ganglion | 1998 |
Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; CHO Cells; COS Cells; Cricetinae; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Indoles; Maleimides; Mitogen-Activated Protein Kinase Kinases; Muscarinic Agonists; Nerve Growth Factors; PC12 Cells; Phorbol 12,13-Dibutyrate; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic | 1998 |
Protein kinase C isoforms differentially control lacrimal gland functions.
Topics: Animals; Calcium; Carbachol; Eye Proteins; Fluorescent Antibody Technique; Homeostasis; Immunohistochemistry; Isoenzymes; Lacrimal Apparatus; Male; Phenylephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Rats; Rats, Wistar; Substrate Specificity | 1998 |
Carbachol-induced desensitization of PLC-beta pathway in rat myometrium: downregulation of Gqalpha/G11alpha.
Topics: Aluminum Compounds; Animals; Atropine; Carbachol; Enzyme Inhibitors; Female; Fluorides; GTP-Binding Proteins; In Vitro Techniques; Indoles; Inositol; Inositol Phosphates; Isoenzymes; Kinetics; Membrane Potentials; Myometrium; N-Methylscopolamine; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Phospholipase C beta; Radioligand Assay; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Type C Phospholipases | 1998 |
Activation of particulate guanylyl cyclase by endothelins in cultured SV-40 transformed cat iris sphincter smooth muscle cells.
Topics: Animals; Calcium; Carbachol; Cats; Cell Line, Transformed; Cyclic GMP; Dose-Response Relationship, Drug; Down-Regulation; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Enzyme Activation; Guanylate Cyclase; Iris; Muscle, Smooth; Nitric Oxide; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Endothelin; Simian virus 40; Vasodilator Agents | 1999 |
Activity of alpha-secretase as the common final effector of protein kinase C-dependent and -independent modulation of amyloid precursor protein metabolism.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Bradykinin; Carbachol; Cells, Cultured; COS Cells; Culture Media, Conditioned; Dipeptides; Endopeptidases; Enzyme Inhibitors; Fibroblasts; Humans; Hydroxamic Acids; Neuroblastoma; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Processing, Post-Translational; Skin; Tumor Cells, Cultured | 1999 |
Protein kinase C mediates muscarinic block of intrinsic bursting in rat hippocampal neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Atropine; Carbachol; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Muscarinic Agonists; Muscarinic Antagonists; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyramidal Cells; Rats; Receptors, Muscarinic; Signal Transduction; Tetraethylammonium; Tetrodotoxin | 1999 |
Carbachol-induced [Ca2+]i increase, but not activation of protein kinase C, stimulates exocytosis in rat parotid acini.
Topics: Adenosine Triphosphate; Amylases; Animals; Calcium; Carbachol; Carcinogens; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Exocytosis; Extracellular Space; Indoles; Intracellular Fluid; Male; Nickel; Parotid Gland; Perfusion; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar | 2000 |
Muscarinic receptors, protein kinase C isozymes and proliferation of astroglial cells: effects of ethanol.
Topics: Astrocytes; Astrocytoma; Blotting, Western; Carbachol; Cell Division; Central Nervous System Depressants; Ethanol; Humans; Isoenzymes; Muscarinic Agonists; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; Subcellular Fractions; Tumor Cells, Cultured | 2000 |
Protein kinase C and calcium regulation of adenylyl cyclase in isolated rat pancreatic islets.
Topics: Adenylyl Cyclases; Animals; Calcium; Carbachol; Cholinergic Agonists; Cyclic AMP; Down-Regulation; In Vitro Techniques; Islets of Langerhans; Male; Peptide Fragments; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sincalide | 2001 |
8-Bromo-cAMP decreases the Ca2+ sensitivity of airway smooth muscle contraction through a mechanism distinct from inhibition of Rho-kinase.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bronchi; Calcium; Carbachol; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Intracellular Signaling Peptides and Proteins; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Protein Serine-Threonine Kinases; Rabbits; rho-Associated Kinases; Trachea | 2004 |
Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon.
Topics: ADP Ribose Transferases; Alkaloids; Amides; Animals; Bacterial Toxins; Benzophenanthridines; Botulinum Toxins; Calcium; Carbachol; Cell Membrane Permeability; Colon, Ascending; Colon, Descending; Escin; Guanosine Triphosphate; Hemolysin Proteins; Intracellular Signaling Peptides and Proteins; Japan; Male; Muscle Contraction; Myocytes, Smooth Muscle; Peptide Fragments; Phenanthridines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; Receptors, Muscarinic; rho-Associated Kinases; Tritium; Type C Phospholipases | 2004 |
Mechanisms of M(1) muscarinic receptor-mediated up-regulation of neuronal nitric oxide synthase in N1E-115 neuroblastoma cells.
Topics: Analysis of Variance; Animals; Atropine; Blotting, Western; Carbachol; Cell Line, Tumor; Chelating Agents; Cholinergic Agonists; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Ionomycin; Ionophores; Mice; Muscarinic Antagonists; Nerve Tissue Proteins; Neuroblastoma; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phorbol 12,13-Dibutyrate; Phorbol Esters; Receptor, Muscarinic M1; Time Factors; Up-Regulation | 2005 |
Effect of phorbol 12,13-dibutyrate on smooth muscle tone in rat stomach fundus.
Topics: Animals; Calcium Chloride; Carbachol; Dose-Response Relationship, Drug; Endothelin-1; Gastric Fundus; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phosphorylcholine; Rats; Rats, Wistar; Serotonin | 2005 |
Adherens junction-associated protein distribution differs in smooth muscle tissue and acutely isolated cells.
Topics: Adherens Junctions; Animals; Carbachol; Cell Separation; Cell Shape; Colon; Cytoskeletal Proteins; Dogs; Fibronectins; Ileum; Immunohistochemistry; Membrane Glycoproteins; Muscle, Smooth; Myocytes, Smooth Muscle; Phorbol 12,13-Dibutyrate; Protein Kinase C-alpha; Rabbits; Stomach; Talin; Trachea; Vinculin | 2007 |
PKC delta-isoform translocation and enhancement of tonic contractions of gastrointestinal smooth muscle.
Topics: Animals; Carbachol; Cytoplasm; Cytoskeleton; Diacylglycerol Kinase; Diterpenes; Female; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Isoenzymes; Male; Maleimides; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Transport; Scopolamine; Subcellular Fractions | 2007 |
A minor role for Ca2+ sensitization in sustained contraction through activation of muscarinic receptor in circular muscle of rat distal colon.
Topics: Alkaloids; Amides; Animals; Benzophenanthridines; Calcium; Carbachol; Carcinogens; Cholinergic Agonists; Colon; Dose-Response Relationship, Drug; Guanosine Triphosphate; Male; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Pyridines; Rats; Rats, Wistar; Receptors, Muscarinic | 2007 |
Negative regulation of endogenous protein kinase Calpha on the dynamic change of carbachol-induced intracellular calcium response in different melanoma cells.
Topics: Adolescent; Calcium Signaling; Carbachol; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Intracellular Space; Male; Melanocytes; Melanoma; Phorbol 12,13-Dibutyrate; Protein Kinase C-alpha; RNA, Messenger; RNA, Small Interfering; Transfection; Wound Healing | 2009 |
SMB myosin heavy chain knockout enhances tonic contraction and reduces the rate of force generation in ileum and stomach antrum.
Topics: Animals; Carbachol; Cholinergic Agonists; Ileum; Mice; Mice, Knockout; Muscle Contraction; Muscle Strength; Muscle, Smooth; Myosin Heavy Chains; Phorbol 12,13-Dibutyrate; Phosphorylation; Potassium; Protein Kinase C-alpha; Pyloric Antrum; Second Messenger Systems; Smooth Muscle Myosins | 2013 |
Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice.
Topics: Adiposity; Amlodipine; Animals; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Chloride; Carbachol; Disease Models, Animal; Epididymis; In Vitro Techniques; Insulin; Insulin Resistance; Male; Metformin; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle Contraction; Obesity; Organ Size; Phorbol 12,13-Dibutyrate; Potassium Chloride; Protein Kinase C; Thinness; Urinary Bladder, Overactive | 2012 |
Tonic and phasic smooth muscle contraction is not regulated by the PKCα - CPI-17 pathway in swine stomach antrum and fundus.
Topics: Animals; Biomechanical Phenomena; Carbachol; Gastric Fundus; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Phosphatase; Phorbol 12,13-Dibutyrate; Protein Kinase C-alpha; Pyloric Antrum; Signal Transduction; Sus scrofa | 2013 |
Rac1 modulates G-protein-coupled receptor-induced bronchial smooth muscle contraction.
Topics: Animals; Bronchi; Carbachol; Endothelin-1; Male; Marine Toxins; Muscle Contraction; Muscle, Smooth; Myosin Light Chains; Oxazoles; Phorbol 12,13-Dibutyrate; Phosphorylation; Potassium; Protein Phosphatase 1; rac1 GTP-Binding Protein; Rats; Rats, Wistar; Receptors, G-Protein-Coupled | 2018 |