phorbol 12,13-dibutyrate has been researched along with bradykinin in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (23.64) | 18.7374 |
| 1990's | 34 (61.82) | 18.2507 |
| 2000's | 8 (14.55) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hashii, M; Higashida, H; Hoshi, N; Noda, M; Nozawa, Y; Shahidullah, M | 1 |
| Feres, T; Funari, CC; Paiva, AC; Paiva, TB | 1 |
| Dray, A; Patel, IA; Perkins, MN; Rueff, A | 1 |
| Cattaneo, MG; Magrini, L; Sparber, SB; Vicentini, LM | 1 |
| Chuang, DM; Lin, WW | 1 |
| Horwitz, J; Ricanati, S | 1 |
| Burgess, GM; Coote, PR; Dunn, PM; Rang, HP; Wood, JN | 1 |
| Fujiwara, N; Warashina, A | 1 |
| Hayes, L; MacLean, DB; Wheeler, F | 1 |
| Bjaaland, T; Bogle, RG; Carter, TD | 1 |
| Béhé, P; Meves, H; Schäfer, S | 1 |
| Daut, J; Mehrke, G | 1 |
| Higashida, H; Myojo, Y; Ogura, A | 1 |
| Bettaney, J; Dray, A; Forster, P | 1 |
| Godson, C; Insel, PA; Weiss, BA | 1 |
| Dunn, PM; Rang, HP | 1 |
| Burgess, GM; Dunn, PM; McNeill, M; Mullaney, I; Rang, HP | 1 |
| Cahill, AL; Horwitz, J; Perlman, RL | 1 |
| Aboolian, A; Nord, EP; Vander Molen, M | 1 |
| Fu, T; Hagiwara, M; Hidaka, H; Nozawa, Y; Okano, Y | 1 |
| Brown, JH; Trilivas, I | 1 |
| Chuang, DM; Dillon-Carter, O | 1 |
| Higashida, H | 1 |
| Dray, A; Perkins, MN | 1 |
| Adams, DJ; Sage, SO; van Breemen, C | 1 |
| Bettaney, J; Dray, A; Forster, P; Perkins, MN | 1 |
| Brown, DA; Higashida, H | 2 |
| Burlingame, SM; Lester, R; Mitchell, PA; Potter, GD; Schmidt, KL | 1 |
| Kopp, UC; Smith, LA | 1 |
| Chulak, C; Couture, R; Foucart, S | 1 |
| Bussolati, O; Franchi-Gazzola, R; Gazzola, GC; Visigalli, R | 1 |
| Bowen, DM; Francis, PT; Pearce, BR; Vekrellis, K; Webster, MT | 1 |
| Colucci, WS; Izzo, NJ; Tulenko, TN | 1 |
| Messlinger, K; Schepelmann, K; Schmidt, RF | 1 |
| Heppel, LA; Huang, NN; Wang, DJ | 1 |
| Castro, E; Delicado, EG; Miras-Portugal, MT; Sen, RP | 1 |
| Fredholm, BB; Lerner, UH; Ljunggren, O; Ljunghall, S; Nordstedt, C | 1 |
| Hill, SJ; Iredale, PA; Kendall, DA; Martin, KF | 1 |
| Corso, M; Horwitz, J; Passarello, B | 1 |
| Barber, LA; Vasko, MR | 1 |
| Rozengurt, E; Seufferlein, T | 1 |
| Nash, MS; Osborne, NN; Wood, JP | 1 |
| Koda, H; Kumazawa, T; Mizumura, K | 1 |
| Fu, LW; Guo, ZL; Longhurst, JC; Symons, JD | 1 |
| Govoni, S; Racchi, M; Sironi, M; Solano, DC | 1 |
| Blase, DK; Cohen, ML; Cox, DA | 1 |
| Hitosugi, H; Kamei, J; Ohsawa, M | 1 |
| Cicha, MZ; Farley, DM; Kopp, UC; Smith, LA | 1 |
| Bari, F; Busija, DW; Erdös, B; Miller, AW; Shimizu, K | 1 |
| Koda, H; Mizumura, K | 1 |
| Busija, DW; Kis, B; Lacza, Z; Miller, AW; Perciaccante, JV; Puskar, M | 1 |
| Ahern, GP; Brooks, IM; Miyares, RL; Wang, XB | 1 |
| Berg, KA; Clarke, WP; Hargreaves, KM; Patwardhan, AM; Sanchez, TA; Silva, YM | 1 |
| Premkumar, LS; Sikand, P | 1 |
55 other study(ies) available for phorbol 12,13-dibutyrate and bradykinin
| Article | Year |
|---|---|
Ba2+ current oscillations modulated by cyclic AMP and phorbol esters in ras-transformed fibroblasts.
Topics: 3T3 Cells; Animals; Barium; Bradykinin; Bucladesine; Cell Line, Transformed; Colforsin; Cyclic AMP; Evoked Potentials; Genes, ras; Kinetics; Kirsten murine sarcoma virus; Membrane Potentials; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Time Factors | 1992 |
Mechanism of the relaxant response of the rat duodenum to bradykinin.
Topics: Animals; Bradykinin; Calcium; Cells, Cultured; Cyclic AMP; Duodenum; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Potassium Channels; Rats; Rats, Wistar | 1992 |
Bradykinin-induced activation of nociceptors: receptor and mechanistic studies on the neonatal rat spinal cord-tail preparation in vitro.
Topics: Animals; Bradykinin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Nociceptors; Phorbol 12,13-Dibutyrate; Protease Inhibitors; Protein Kinase C; Rats; Receptors, Bradykinin; Receptors, Neurotransmitter; Second Messenger Systems; Spinal Cord; Spinal Nerve Roots; Tail | 1992 |
Interaction between mitogens upon intracellular Ca2+ pools in murine fibroblasts.
Topics: 3T3 Cells; Animals; Bombesin; Bradykinin; Calcium; Calcium Channels; Drug Interactions; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ion Channel Gating; Ionomycin; Mice; Phorbol 12,13-Dibutyrate; Platelet-Derived Growth Factor; Signal Transduction; Stimulation, Chemical; Terpenes; Thapsigargin; Vasopressins | 1992 |
Regulation of bradykinin-induced phosphoinositide turnover in cultured cerebellar astrocytes: possible role of protein kinase C.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Bradykinin; Cells, Cultured; Cerebellum; Endothelins; Norepinephrine; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Virulence Factors, Bordetella | 1992 |
Bradykinin and phorbol dibutyrate activate phospholipase D in PC12 cells by different mechanisms.
Topics: Animals; Bradykinin; Diglycerides; Enzyme Activation; Glycerophospholipids; PC12 Cells; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Substrate Specificity | 1992 |
Bradykinin evoked depolarization of a novel neuroblastoma x DRG neurone hybrid cell line (ND7/23).
Topics: Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcium; Cell Membrane; Cells, Cultured; Cytosol; Evoked Potentials; Ganglia, Spinal; Hybrid Cells; Inositol Phosphates; Ionomycin; Membrane Potentials; Neuroblastoma; Neurons; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Receptors, Bradykinin; Receptors, Neurotransmitter; Second Messenger Systems; Staurosporine | 1991 |
Differential effects of protein kinase C activation on catecholamine secretions evoked by stimulations of various receptors in the rat adrenal medulla.
Topics: Adrenal Medulla; Animals; Bradykinin; Catecholamines; Diterpenes; Enzyme Activation; GTP-Binding Proteins; Histamine; In Vitro Techniques; Male; Muscarine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Terpenes | 1991 |
Basal and stimulated release of substance P from dissociated cultures of vagal sensory neurons.
Topics: Animals; Animals, Newborn; Bradykinin; Capsaicin; Chromatography, High Pressure Liquid; Kinetics; Neurons, Afferent; Nodose Ganglion; Phorbol 12,13-Dibutyrate; Potassium; Rats; Rats, Inbred Strains; Substance P; Vagus Nerve | 1990 |
Spiking of intracellular calcium ion concentration in single cultured pig aortic endothelial cells stimulated with ATP or bradykinin.
Topics: Adenosine Triphosphate; Animals; Aorta; Bradykinin; Calcium; Cells, Cultured; Diglycerides; Endothelium, Vascular; Enzyme Activation; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Swine | 1991 |
Inhibition of the M current in NG 108-15 neuroblastoma x glioma hybrid cells.
Topics: Alkaloids; Animals; Bradykinin; Hybrid Cells; Membrane Potentials; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Staurosporine; Tumor Cells, Cultured; Xanthines | 1991 |
The electrical response of cultured guinea-pig coronary endothelial cells to endothelium-dependent vasodilators.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Bradykinin; Calcium; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Guinea Pigs; Histamine; Membrane Potentials; Phorbol 12,13-Dibutyrate; Potassium; Tubocurarine; Vasodilator Agents | 1990 |
Bradykinin-evoked acetylcholine release via inositol trisphosphate-dependent elevation in free calcium in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Acetylcholine; Animals; Barium; Bradykinin; Calcium; Cell Line; Evoked Potentials; Glioma; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Rats; Synapses | 1990 |
Resiniferatoxin, a potent capsaicin-like stimulator of peripheral nociceptors in the neonatal rat tail in vitro.
Topics: Alkaloids; Animals; Animals, Newborn; Bradykinin; Capsaicin; Diterpenes; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nociceptors; Peripheral Nerves; Phorbol 12,13-Dibutyrate; Rats; Rats, Inbred Strains; Regional Blood Flow; Staurosporine; Tail | 1990 |
Differential activation of protein kinase C alpha is associated with arachidonate release in Madin-Darby canine kidney cells.
Topics: Animals; Arachidonic Acids; Bradykinin; Cell Line; Diglycerides; Dogs; Enzyme Activation; Kidney; Kinetics; Phorbol 12,13-Dibutyrate; Phospholipids; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
Bradykinin-induced depolarization of primary afferent nerve terminals in the neonatal rat spinal cord in vitro.
Topics: Animals; Animals, Newborn; Binding Sites; Bradykinin; Cadmium; Calcium; Capsaicin; In Vitro Techniques; Nerve Endings; Neuromuscular Depolarizing Agents; Neurons, Afferent; Phorbol 12,13-Dibutyrate; Rats; Rats, Inbred Strains; Second Messenger Systems; Spinal Cord | 1990 |
Second messengers involved in the mechanism of action of bradykinin in sensory neurons in culture.
Topics: Animals; Biomechanical Phenomena; Bradykinin; Calcium; Cells, Cultured; Electrophysiology; Enzyme Activation; Ganglia, Spinal; Neurons, Afferent; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Phosphoric Diester Hydrolases; Protein Kinase C; Second Messenger Systems | 1989 |
Phosphorylation of tyrosine hydroxylase in protein kinase C-deficient PC12 cells.
Topics: Animals; Bradykinin; Cell Line; Diglycerides; Nerve Growth Factors; Pheochromocytoma; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Rats; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1989 |
Differential effects of phorbol esters on PGE2 and bradykinin-induced elevation of [Cai2+] in MDCK cells.
Topics: Animals; Benzofurans; Bradykinin; Calcium; Cell Line; Dinoprostone; Fluorescent Dyes; Fura-2; Kidney; Kinetics; Phorbol 12,13-Dibutyrate; Prostaglandins; Tetradecanoylphorbol Acetate | 1989 |
Bradykinin-induced translocation of protein kinases C in neuroblastoma NCB-20 cell: dependence on 1,2-diacylglycerol content and free calcium.
Topics: Animals; Bradykinin; Calcium; Cell Compartmentation; Diglycerides; Glycerides; Humans; Hybrid Cells; Isoenzymes; Neuroblastoma; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrimidinones; Thiazoles; Time Factors; Tumor Cells, Cultured | 1989 |
Increases in intracellular Ca2+ regulate the binding of [3H]phorbol 12,13-dibutyrate to intact 1321N1 astrocytoma cells.
Topics: Astrocytoma; Binding Sites; Bradykinin; Calcium; Carbachol; Cell Membrane; Cytosol; Diglycerides; Ethers; Histamine; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Kinetics; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; Tumor Cells, Cultured | 1989 |
Characterization of bradykinin-induced phosphoinositide turnover in neurohybrid NCB-20 cells.
Topics: Animals; Bradykinin; Cell Line; Diphenhydramine; GTP-Binding Proteins; Kinetics; Lithium; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylinositols; Triprolidine; Type C Phospholipases | 1988 |
Acetylcholine release by bradykinin, inositol 1,4,5-trisphosphate and phorbol dibutyrate in rodent neuroblastoma cells.
Topics: Acetylcholine; Action Potentials; Animals; Bradykinin; Calcium; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Membrane Potentials; Mice; Muscles; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Sugar Phosphates; Synapses; Synaptic Transmission; Time Factors | 1988 |
Bradykinin activates peripheral capsaicin-sensitive fibres via a second messenger system.
Topics: Alkaloids; Animals; Animals, Newborn; Bradykinin; Capsaicin; Nociceptors; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Receptors, Bradykinin; Receptors, Neurotransmitter; Second Messenger Systems; Spinal Cord; Staurosporine; Tail | 1988 |
Synchronized oscillations in cytoplasmic free calcium concentration in confluent bradykinin-stimulated bovine pulmonary artery endothelial cell monolayers.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Benzofurans; Bradykinin; Calcium; Cattle; Cells, Cultured; Cytoplasm; Endothelium, Vascular; Fura-2; Isoquinolines; Kinetics; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Pulmonary Artery | 1989 |
Bradykinin-induced stimulation of afferent fibres is mediated through protein kinase C.
Topics: Alkaloids; Animals; Bradykinin; Capsaicin; Enzyme Inhibitors; In Vitro Techniques; Membrane Potentials; Neurons, Afferent; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Spinal Cord; Staurosporine | 1988 |
Inositol 1,4,5-trisphosphate and diacylglycerol mimic bradykinin effects on mouse neuroblastoma x rat glioma hybrid cells.
Topics: Animals; Bradykinin; Calcium; Diglycerides; Enzyme Activation; Glycerides; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Membrane Potentials; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Potassium; Protein Kinase C; Rats; Sugar Phosphates; Time Factors | 1988 |
Ca2+-dependent K+ channels in neuroblastoma hybrid cells activated by intracellular inositol trisphosphate and extracellular bradykinin.
Topics: Animals; Bradykinin; Calcium; Electric Conductivity; Glioma; Hybrid Cells; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Potassium Channels; Rats; Sugar Phosphates; Tumor Cells, Cultured | 1988 |
Taurodeoxycholate and the developing rabbit distal colon: absence of secretory effect.
Topics: Animals; Bradykinin; Carbachol; Colon; Deoxycholic Acid; Epithelium; Female; Male; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rabbits; Reference Values; Serotonin; Taurodeoxycholic Acid; Theophylline | 1987 |
A role for protein kinase C in bradykinin-mediated activation of renal pelvic sensory receptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bradykinin; Enzyme Activation; Isoquinolines; Kidney Pelvis; Male; Naphthalenes; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Staurosporine | 1995 |
Modulatory effect of bradykinin on the release of noradrenaline from rat isolated atria.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Angiotensin II; Animals; Bradykinin; Diclofenac; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Fenoterol; Heart Atria; Indoles; Male; Maleimides; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar | 1995 |
The regulation of sodium-dependent transport of anionic amino acids in cultured human fibroblasts.
Topics: Adolescent; Alkaloids; Arginine; Aspartic Acid; Becaplermin; Biological Transport; Bradykinin; Cells, Cultured; Down-Regulation; Enzyme Activation; Fibroblasts; Humans; Male; Membrane Potentials; Phorbol 12,13-Dibutyrate; Platelet-Derived Growth Factor; Protein Kinase C; Proto-Oncogene Proteins c-sis; Skin; Sodium; Staurosporine | 1994 |
Factors affecting the beta-amyloid precursor in PC12 cells.
Topics: Amyloid beta-Protein Precursor; Animals; Bradykinin; Cell Differentiation; Chloroquine; Kinetics; Molecular Weight; Nerve Growth Factors; Neurons; PC12 Cells; Phorbol 12,13-Dibutyrate | 1993 |
Phorbol esters and norepinephrine destabilize alpha 1B-adrenergic receptor mRNA in vascular smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta; Bradykinin; Cells, Cultured; Diglycerides; Down-Regulation; Ethers, Cyclic; Inositol Phosphates; Isoquinolines; Kinetics; Models, Biological; Muscle, Smooth, Vascular; Norepinephrine; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Rabbits; Receptors, Adrenergic, alpha-1; RNA, Messenger; Tetradecanoylphorbol Acetate | 1994 |
The effects of phorbol ester on slowly conducting afferents of the cat's knee joint.
Topics: Animals; Bradykinin; Bucladesine; Cats; Dibutyryl Cyclic GMP; Diglycerides; Dinoprostone; Epoprostenol; Hindlimb; Knee Joint; Neural Conduction; Neurons, Afferent; Nociceptors; Phorbol 12,13-Dibutyrate; Protein Kinase C; Signal Transduction | 1993 |
Stimulation of aged human lung fibroblasts by extracellular ATP via suppression of arachidonate metabolism.
Topics: Adenosine Triphosphate; Arachidonic Acid; Bradykinin; Cell Division; Cell Line; Cellular Senescence; Colforsin; Cyclic AMP; Dinoprostone; DNA Replication; Embryo, Mammalian; Fibroblasts; Humans; Insulin; Kinetics; Lung; Lysophospholipids; Phorbol 12,13-Dibutyrate; Protein Kinase C; Time Factors | 1993 |
Effect of P2Y agonists on adenosine transport in cultured chromaffin cells.
Topics: Adenosine; Adenosine Diphosphate; Adenylyl Imidodiphosphate; Adrenal Medulla; Animals; Biological Transport; Bradykinin; Carbachol; Cattle; Cells, Cultured; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Kinetics; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Purinergic; Thionucleotides | 1993 |
Role of protein kinase C in bradykinin-induced prostaglandin formation in osteoblasts.
Topics: Alkaloids; Animals; Bradykinin; Calcimycin; Cell Membrane; Cells, Cultured; Dinoprostone; Enzyme Activation; Hydrocortisone; Indomethacin; Mice; Osteoblasts; Phorbol 12,13-Dibutyrate; Prostaglandins; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
The effects of beta-phorbol-12,13 dibutyrate on agonist-induced increases in [Ca2+]i in N1E-115 cells. Differential modulation of responses to angiotensin II and bradykinin.
Topics: Alkaloids; Angiotensin II; Animals; Bradykinin; Calcium; Down-Regulation; Enzyme Activation; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Staurosporine; Tumor Cells, Cultured | 1993 |
Bradykinin stimulates phospholipase D in PC12 cells by a mechanism which is independent of increases in intracellular Ca2+.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Carbachol; Enzyme Inhibitors; Ethanol; Ionomycin; Ionophores; Neurons; PC12 Cells; Phorbol 12,13-Dibutyrate; Phospholipase D; Rats; Stimulation, Chemical; Terpenes; Thapsigargin | 1995 |
Activation of protein kinase C augments peptide release from rat sensory neurons.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Carcinogens; Cells, Cultured; Down-Regulation; Enzyme Activation; Female; Mice; Neurons, Afferent; Neuropeptides; Phorbol 12,13-Dibutyrate; Potassium; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Substance P | 1996 |
Galanin, neurotensin, and phorbol esters rapidly stimulate activation of mitogen-activated protein kinase in small cell lung cancer cells.
Topics: Bradykinin; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Carcinoma, Small Cell; Down-Regulation; Enzyme Activation; Flavonoids; Galanin; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Neoplasm Proteins; Neuropeptides; Neurotensin; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Ribosomal Protein S6 Kinases; Tumor Cells, Cultured; Tumor Stem Cell Assay; Virulence Factors, Bordetella | 1996 |
Protein kinase C activation by serotonin potentiates agonist-induced stimulation of cAMP production in cultured rat retinal pigment epithelial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Isoproterenol; Naphthalenes; Phorbol 12,13-Dibutyrate; Pigment Epithelium of Eye; Protein Kinase C; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Staurosporine | 1997 |
Evidence that protein kinase C activation is involved in the excitatory and facilitatory effects of bradykinin on canine visceral nociceptors in vitro.
Topics: Adaptation, Physiological; Animals; Bradykinin; Dogs; Male; Neural Conduction; Nociceptors; Pain; Phorbol 12,13-Dibutyrate; Protein Kinase C; Sensory Receptor Cells; Sensory Thresholds; Staurosporine; Temperature; Testis; Visceral Afferents | 1997 |
Signal transduction in activation of ischemically sensitive abdominal visceral afferents: role of PKC.
Topics: Abdomen; Afferent Pathways; Animals; Bradykinin; Cats; Enzyme Activation; Enzyme Inhibitors; Female; Ischemia; Male; Nerve Fibers; Phorbol 12,13-Dibutyrate; Protein Kinase C; Signal Transduction; Viscera | 1998 |
Activity of alpha-secretase as the common final effector of protein kinase C-dependent and -independent modulation of amyloid precursor protein metabolism.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Bradykinin; Carbachol; Cells, Cultured; COS Cells; Culture Media, Conditioned; Dipeptides; Endopeptidases; Enzyme Inhibitors; Fibroblasts; Humans; Hydroxamic Acids; Neuroblastoma; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Processing, Post-Translational; Skin; Tumor Cells, Cultured | 1999 |
Bradykinin and phorbol ester but not 5-HT2B receptor activation stimulate phospholipase D activity in the rat stomach fundus.
Topics: Animals; Bradykinin; Calcium; Enzyme Activation; Gastric Fundus; Glycerophospholipids; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phospholipase D; Protein Kinase C; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin; Signal Transduction; Stomach | 1999 |
Effect of diabetes on bradykinin-induced thermal hyperalgesia in mice.
Topics: Animals; Bradykinin; Diabetes Mellitus, Experimental; Enzyme Activators; Enzyme Inhibitors; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naphthalenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Reaction Time | 2000 |
Activation of renal mechanosensitive neurons involves bradykinin, protein kinase C, PGE(2), and substance P.
Topics: Adrenergic beta-Antagonists; Analgesics; Animals; Antimetabolites; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Indoles; Isoindoles; Kidney; Kidney Pelvis; Male; Mechanoreceptors; Naphthalenes; Natriuresis; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Phorbol 12,13-Dibutyrate; Pressure; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Receptors, Bradykinin; Receptors, Neurokinin-1; Substance P | 2000 |
Role of endothelium in hyperemia during cortical spreading depression (CSD) in the rat.
Topics: Acetylcholine; Animals; Bradykinin; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Cortical Spreading Depression; Endothelium, Vascular; Enzyme Inhibitors; Fructose; Hyperemia; Insulin Resistance; Male; Membrane Potentials; Nitroprusside; Phorbol 12,13-Dibutyrate; Rats; Rats, Sprague-Dawley; Vasodilation | 2002 |
Sensitization to mechanical stimulation by inflammatory mediators and by mild burn in canine visceral nociceptors in vitro.
Topics: Animals; Bradykinin; Burns; Colforsin; Dinoprostone; Dogs; Histamine; Hot Temperature; Inflammation Mediators; Nociceptors; Phorbol 12,13-Dibutyrate; Physical Stimulation; Protons; Viscera | 2002 |
Hydrogen peroxide acts as an EDHF in the piglet pial vasculature in response to bradykinin.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arteries; Biological Factors; Bradykinin; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Female; Hydrogen Peroxide; Indomethacin; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Phorbol 12,13-Dibutyrate; Pia Mater; Potassium Channel Blockers; Potassium Channels; Swine; Vasodilation; Vasodilator Agents | 2002 |
Extracellular cations sensitize and gate capsaicin receptor TRPV1 modulating pain signaling.
Topics: Adenosine Triphosphate; Aminobutyrates; Animals; Arachidonic Acids; Behavior, Animal; Bradykinin; Calcium; Calcium Channel Blockers; Capsaicin; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Endocannabinoids; Extracellular Space; Humans; Hydrogen-Ion Concentration; Magnesium Sulfate; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Microinjections; Models, Biological; Mutagenesis; Neurons; Nodose Ganglion; Oocytes; Pain; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Polyunsaturated Alkamides; Protein Kinase C; Signal Transduction; Temperature; Time Factors; Transfection; TRPV Cation Channels | 2005 |
Rapid modulation of micro-opioid receptor signaling in primary sensory neurons.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Arachidonic Acid; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Gene Expression; Inositol Phosphates; Male; Neurons, Afferent; Phorbol 12,13-Dibutyrate; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Receptor, PAR-2; Receptors, Opioid, mu; Signal Transduction; Type C Phospholipases | 2007 |
Potentiation of glutamatergic synaptic transmission by protein kinase C-mediated sensitization of TRPV1 at the first sensory synapse.
Topics: Animals; Bradykinin; Calcium; Capsaicin; Cells, Cultured; Coculture Techniques; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Ganglia, Spinal; Glutamine; Indoles; Maleimides; Neuronal Plasticity; Neurons, Afferent; Pain; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Phosphorylation; Posterior Horn Cells; Presynaptic Terminals; Protein Kinase C; Rats; Rats, Sprague-Dawley; Synaptic Transmission; TRPV Cation Channels; Type C Phospholipases | 2007 |