phorbol 12,13-dibutyrate has been researched along with bisindolylmaleimide i in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 28 (59.57) | 18.2507 |
| 2000's | 15 (31.91) | 29.6817 |
| 2010's | 4 (8.51) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ajakane, M; Baudet, V; Bellevergue, P; Boissin, P; Boursier, E; Coste, H; Grand-Perret, T; Loriolle, F; Pianetti, P; Toullec, D | 1 |
| Rozengurt, E; Seufferlein, T | 1 |
| Mironneau, C; Mironneau, J; Neuilly, G; Sayet, I | 1 |
| Barnes, PJ; Haddad, EB; Mak, JC; Rousell, J | 1 |
| Coderre, TJ; Parent, A; Pitcher, GM; Quirion, R; Yashpal, K | 1 |
| Mitchell, R; Sim, P | 1 |
| Clegg, RA; Johnson, MS; Mitchell, R; Simpson, J | 2 |
| Black, JL; Yang, KX | 1 |
| Craven, PA; DeRubertis, FR; Studer, RK | 1 |
| Ison, AJ; Johnson, MS; MacEwan, DJ; Mitchell, R; Thomson, FJ; Wolbers, WB | 1 |
| Rozengurt, E; Sinnett-Smith, J; Valverde, AM; Zachary, I | 1 |
| Bouzyk, M; Rozengurt, E; Walsh, JH | 1 |
| Berrie, CP; Cobbold, PH | 1 |
| Erusalimsky, JD; Hong, Y; Martin, JF; Vainchenker, W | 1 |
| Cohen, ML; Cox, DA | 1 |
| Baier, G; Bauer, B; Fresser, F; Giselbrecht, S; Grunicke, HH; Gschwendt, M; Hellbert, K; Uberall, F | 1 |
| Gailly, P; Gong, MC; Somlyo, AP; Somlyo, AV | 1 |
| Coffman, TM; Spurney, RF | 1 |
| Freissmuth, M; Hutter, C; Karel, A; Schütz, W; Sexl, V; Zezula, J | 1 |
| Alemany, S; Fernández-Renart, M; Lisbona, C | 1 |
| Almazan, G; Larocca, JN | 1 |
| Buxbaum, JD; Czernik, AJ; Desdouits, F; Desdouits-Magnen, J; Greengard, P; Nairn, AC; Saltiel, AR; Syu, LJ; Takeda, S | 1 |
| Crooke, ST; Levesque, L | 1 |
| Barnes, PJ; Dupont, LJ; Mak, JC; Pype, JL; Verleden, GM | 1 |
| Paolucci, L; Rozengurt, E | 1 |
| Itoh, H; Kaiura, TL; Kent, KC | 1 |
| Dobashi, K; Iizuka, K; Ishizuka, T; Mori, M; Nakazawa, T; Samizo, K; Tsukagoshi, H; Yoshii, A | 1 |
| Bunnett, NW; Defea, KA; Déry, O | 1 |
| Brautigan, DL; Eto, M; Kitazawa, T; Mukai, H; Ono, Y; Yazawa, M | 1 |
| Nagy, Z; Radeff, J; Stern, PH | 1 |
| Cho, H; Earm, YE; Ho, WK; Youm, JB | 1 |
| Bae, D; Cantrell, D; Nel, AE; Rozengurt, E; Yuan, J | 1 |
| Bang, JH; Jang, CH; Joo, I; Jung, MW; Kim, C; Kim, SU; Mook-Jung, I | 1 |
| Searl, TJ; Silinsky, EM | 1 |
| Egawa, M; Hori, M; Kanzaki, H; Karaki, H; Kim, YS; Nakazawa, H; Ozaki, H; Seto, M; Yasuda, K | 1 |
| Belevych, AE; Harvey, RD; Juranek, I | 1 |
| Chaban, VV; Ennes, HS; Li, J; Mayer, EA; McRoberts, JA; Nie, J | 1 |
| Argent, BE; Gray, MA; Hegyi, P; Rácz, G; Rakonczay, Z; Tiszlavicz, L; Tóth, A; Varga, G; Varró, A | 1 |
| Furness, JB; Poole, DP | 1 |
| Callaghan, BP; Cobine, CA; Keef, KD | 1 |
| Namiki, H; Takahashi, H | 1 |
| Bond, JA; Errington, R; Gescher, AJ; Lemoine, NR; Smith, PJ; Verschoyle, RD; Wiltshire, M; Wynford-Thomas, D | 1 |
| Chiba, Y; Hashimoto, Y; Kurihara, Y; Misawa, M; Sakai, H | 1 |
| Rattan, S; Singh, J | 2 |
| He, A; Jiang, L; Li, W; Liu, Y; Lv, J; Tang, J; Tu, Q; Wu, J; Xu, Z; Zhong, Y; Zhou, X; Zhu, X | 1 |
47 other study(ies) available for phorbol 12,13-dibutyrate and bisindolylmaleimide i
| Article | Year |
|---|---|
The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Blood Platelets; Bombesin; Collagen; DNA; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Fibroblasts; Humans; Indoles; Maleimides; Mice; Phorbol 12,13-Dibutyrate; Phosphorylation; Platelet Aggregation; Protein Kinase C; Staurosporine; Structure-Activity Relationship; Thymidine; Vimentin | 1991 |
Sphingosylphosphorylcholine rapidly induces tyrosine phosphorylation of p125FAK and paxillin, rearrangement of the actin cytoskeleton and focal contact assembly. Requirement of p21rho in the signaling pathway.
Topics: 3T3 Cells; Actins; ADP Ribose Transferases; Animals; Blotting, Western; Bombesin; Botulinum Toxins; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion Molecules; Cytoskeletal Proteins; Cytoskeleton; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Proteins; Indoles; Kinetics; Maleimides; Mice; Microinjections; Paxillin; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylcholine; Phosphotyrosine; Protein-Tyrosine Kinases; rho GTP-Binding Proteins; Signal Transduction; Sphingosine | 1995 |
Influence of spaceflight, hindlimb suspension, and venous occlusion on alpha 1-adrenoceptors in rat vena cava.
Topics: Animals; Hindlimb; In Vitro Techniques; Indoles; Isometric Contraction; Male; Maleimides; Norepinephrine; Phorbol 12,13-Dibutyrate; Prazosin; Protein Kinase C; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, alpha-1; Space Flight; Venae Cavae; Weightlessness Simulation | 1995 |
Transcriptional down-regulation of m2 muscarinic receptor gene expression in human embryonic lung (HEL 299) cells by protein kinase C.
Topics: Blotting, Northern; Cell Line; Cell Nucleus; Colforsin; Cycloheximide; Dactinomycin; Embryo, Mammalian; Gene Expression Regulation; Half-Life; Humans; Indoles; Kinetics; Lung; Maleimides; N-Methylscopolamine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; RNA, Messenger; Scopolamine Derivatives; Time Factors; Transcription, Genetic | 1995 |
Noxious thermal and chemical stimulation induce increases in 3H-phorbol 12,13-dibutyrate binding in spinal cord dorsal horn as well as persistent pain and hyperalgesia, which is reduced by inhibition of protein kinase C.
Topics: Alkaloids; Analysis of Variance; Animals; Benzophenanthridines; Formaldehyde; Functional Laterality; Hindlimb; Hot Temperature; Hyperalgesia; Indoles; Injections, Spinal; Kinetics; Male; Maleimides; Pain; Phenanthridines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Spinal Cord; Time Factors | 1995 |
Activation of MAP kinase by the LHRH receptor through a PKC-dependent pertussis toxin-sensitive mechanism.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Gonadotropin-Releasing Hormone; Indoles; Kinetics; Maleimides; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, LHRH; Virulence Factors, Bordetella | 1995 |
The properties of protein kinase C zeta purified from alpha T3-1 cells using hydroxyapatite chromatography.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cell Line; Chromatography; Chromatography, DEAE-Cellulose; Durapatite; Indoles; Isoenzymes; Isoquinolines; Kinetics; Maleimides; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats | 1995 |
The involvement of protein kinase C in the contraction of human airway smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Bronchi; Histamine; Humans; In Vitro Techniques; Indoles; Isoquinolines; Maleimides; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Staurosporine | 1995 |
Low-density lipoprotein stimulation of mesangial cell fibronectin synthesis: role of protein kinase C and transforming growth factor-beta.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Fatty Acids, Unsaturated; Female; Fibronectins; Glomerular Mesangium; Hydrazines; Indoles; Intracellular Signaling Peptides and Proteins; Lipoproteins, LDL; Maleimides; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Phorbol 12,13-Dibutyrate; Phosphorylation; Piroxicam; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Thromboxane A2; Transforming Growth Factor beta | 1995 |
The differential effects of protein kinase C activators and inhibitors on rat anterior pituitary hormone release.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Anti-Bacterial Agents; Benzophenanthridines; Carcinogens; Cerebral Cortex; Cytosol; Diterpenes; Female; Growth Hormone; Indoles; Isomerism; Isoquinolines; Lung; Luteinizing Hormone; Maleimides; Phenanthridines; Phorbol 12,13-Dibutyrate; Piperazines; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Terpenes; Tritium | 1993 |
Bombesin stimulation of p125 focal adhesion kinase tyrosine phosphorylation. Role of protein kinase C, Ca2+ mobilization, and the actin cytoskeleton.
Topics: 3T3 Cells; Actins; Animals; Bombesin; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Adhesion Molecules; Colchicine; Cytochalasin D; Cytoskeleton; Diglycerides; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Indoles; Intracellular Signaling Peptides and Proteins; Kinetics; Maleimides; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proteins; Terpenes; Thapsigargin; Tyrosine | 1993 |
Homologous desensitization of bombesin-induced increases in intracellular Ca2+ in quiescent Swiss 3T3 cells involves a protein kinase C-independent mechanism.
Topics: 3T3 Cells; Animals; Bombesin; Calcium; Cell Division; Dose-Response Relationship, Drug; Down-Regulation; Feedback; Indoles; Iodine Radioisotopes; Maleimides; Mice; Phorbol 12,13-Dibutyrate; Precipitin Tests; Protein Kinase C; Receptors, Bombesin; Receptors, Neurotransmitter; Signal Transduction; Vasopressins | 1993 |
Both activators and inhibitors of protein kinase C promote the inhibition of phenylephrine-induced [Ca2+]i oscillations in single intact rat hepatocytes.
Topics: Alkaloids; Amino Acid Sequence; Animals; Benzophenanthridines; Calcium; Enzyme Activation; Enzyme Inhibitors; Indoles; Liver; Male; Maleimides; Molecular Sequence Data; Oligopeptides; Phenanthridines; Phenylephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Staurosporine | 1995 |
Inhibition of protein kinase C suppresses megakaryocytic differentiation and stimulates erythroid differentiation in HEL cells.
Topics: Aphidicolin; Biomarkers; Blood Proteins; Cell Cycle; Cell Differentiation; Enzyme Inhibitors; Erythroid Precursor Cells; Gene Expression Regulation, Leukemic; Globins; Glycophorins; Hematopoietic Stem Cells; Hemin; Humans; Indoles; Leukemia, Erythroblastic, Acute; Maleimides; Megakaryocytes; Neoplasm Proteins; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Separation of H7-resistant protein kinase C isoforms from gonadotroph-derived alpha T3-1 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Indoles; Isoenzymes; Isoquinolines; Maleimides; Phorbol 12,13-Dibutyrate; Piperazines; Pituitary Gland, Anterior; Protein Kinase C | 1996 |
Lysophosphatidylcholine stimulates phospholipase D in human coronary endothelial cells: role of PKC.
Topics: Alkaloids; Benzophenanthridines; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Humans; Indoles; Lysophosphatidylcholines; Maleimides; Naphthalenes; Phenanthridines; Phorbol 12,13-Dibutyrate; Phospholipase D; Protein Kinase C | 1996 |
Conventional PKC-alpha, novel PKC-epsilon and PKC-theta, but not atypical PKC-lambda are MARCKS kinases in intact NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Enzyme Induction; Enzyme Inhibitors; Indoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Maleimides; Membrane Proteins; Mice; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Proteins | 1997 |
Possible role of atypical protein kinase C activated by arachidonic acid in Ca2+ sensitization of rabbit smooth muscle.
Topics: Adrenergic alpha-Agonists; Amino Acid Sequence; Animals; Arachidonic Acid; Calcium; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Femoral Artery; In Vitro Techniques; Indoles; Isoenzymes; Isometric Contraction; Kinetics; Maleimides; Molecular Sequence Data; Muscle, Smooth, Vascular; Myosin Light Chains; Peptide Fragments; Phenylephrine; Phorbol 12,13-Dibutyrate; Phosphorylation; Portal Vein; Protein Kinase C; Protein Kinase C-alpha; Rabbits; Sequence Homology, Amino Acid; Substrate Specificity; Type C Phospholipases | 1997 |
The C-terminus of the thromboxane receptor contributes to coupling and desensitization in a mouse mesangial cell line.
Topics: Amino Acid Sequence; Animals; Calcium; Cell Line; Glomerular Mesangium; Indoles; Maleimides; Mice; Molecular Sequence Data; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Thromboxane; Structure-Activity Relationship | 1997 |
The cyclin-dependent kinase inhibitor p21cip1 mediates the growth inhibitory effect of phorbol esters in human venous endothelial cells.
Topics: Cell Division; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Endothelium, Vascular; Enzyme Inhibitors; Fibroblast Growth Factor 2; Flavonoids; G1 Phase; Humans; Indoles; Maleimides; Phorbol 12,13-Dibutyrate; Polyenes; Protein Kinase C; RNA, Messenger; Signal Transduction; Sirolimus; Tumor Suppressor Protein p53 | 1997 |
Regulation of ERK2 dephosphorylation in G1-stimulated rat T lymphoblasts.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cycloheximide; Dactinomycin; Dual Specificity Phosphatase 2; Enzyme Activation; Enzyme Inhibitors; G1 Phase; Indoles; Maleimides; Mitogen-Activated Protein Kinase 1; Nucleic Acid Synthesis Inhibitors; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Protein Phosphatase 2; Protein Synthesis Inhibitors; Protein Tyrosine Phosphatases; Rats; RNA, Messenger; T-Lymphocytes; Vanadates | 1997 |
Acetylcholine agonists stimulate mitogen-activated protein kinase in oligodendrocyte progenitors by muscarinic receptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Atropine; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cells, Cultured; Cholinergic Agents; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Indoles; Maleimides; Mitogen-Activated Protein Kinase 1; Oligodendroglia; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction; Stem Cells; Tetradecanoylphorbol Acetate | 1997 |
Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; CHO Cells; COS Cells; Cricetinae; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Indoles; Maleimides; Mitogen-Activated Protein Kinase Kinases; Muscarinic Agonists; Nerve Growth Factors; PC12 Cells; Phorbol 12,13-Dibutyrate; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic | 1998 |
Depletion of protein kinase C-alpha by antisense oligonucleotides alters beta-adrenergic function and reverses the phorbol ester-induced reduction of isoproterenol-induced adenosine 3'-5'-cyclic monophosphate accumulation in murine Swiss 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cholera Toxin; Colforsin; Cyclic AMP; Indoles; Isoenzymes; Isoproterenol; Maleimides; Mice; Oligonucleotides, Antisense; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Adrenergic, beta; RNA, Messenger | 1998 |
Desensitization of the histamine H1-receptor and transcriptional down-regulation of histamine H1-receptor gene expression in bovine tracheal smooth muscle.
Topics: Animals; Blotting, Northern; Cattle; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Histamine; In Vitro Techniques; Indoles; Inositol Phosphates; Maleimides; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Histamine H1; Sodium Fluoride; Trachea; Transcription, Genetic; Tritium | 1998 |
Protein kinase D in small cell lung cancer cells: rapid activation through protein kinase C.
Topics: Amino Acid Sequence; Bombesin; Carcinogens; Carcinoma, Small Cell; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Lung Neoplasms; Maleimides; Molecular Sequence Data; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tumor Cells, Cultured | 1999 |
The role of mitogen-activated protein kinase and protein kinase C in fibronectin production in human vascular smooth muscle cells.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Fibronectins; Flavonoids; Humans; Indoles; Maleimides; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Protein Kinase C; Transforming Growth Factor beta | 1999 |
A major role for the rho-associated coiled coil forming protein kinase in G-protein-mediated Ca2+ sensitization through inhibition of myosin phosphatase in rabbit trachea.
Topics: Amides; Animals; Calcium; Enzyme Inhibitors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Myosin-Light-Chain Phosphatase; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; Trachea | 1999 |
Protein kinase C-mediated desensitization of the neurokinin 1 receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Calcium Signaling; Cell Line; DNA Primers; Enzyme Activation; Enzyme Inhibitors; Indoles; Kidney; Maleimides; Molecular Sequence Data; Mutagenesis, Site-Directed; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Conformation; Protein Kinase C; Rats; Receptors, Neurokinin-1; Recombinant Proteins; Sequence Deletion; Substance P; Transfection | 2001 |
Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C alpha and delta isoforms.
Topics: Amides; Amino Acid Sequence; Animals; Aorta; Carbazoles; Chromatography; Chromatography, Affinity; Chromatography, Ion Exchange; Durapatite; Enzyme Activation; Enzyme Inhibitors; Histamine; In Vitro Techniques; Indoles; Isoenzymes; Kinetics; Maleimides; Molecular Sequence Data; Muscle Contraction; Muscle Proteins; Muscle Relaxants, Central; Muscle, Smooth, Vascular; Myelin Basic Protein; Myosin-Light-Chain Phosphatase; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Pyridines; Recombinant Proteins; Substrate Specificity; Swine; Vasoconstriction | 2001 |
Stimulation of interleukin-6 promoter by parathyroid hormone, tumor necrosis factor alpha, and interleukin-1beta in UMR-106 osteoblastic cells is inhibited by protein kinase C antagonists.
Topics: Animals; Enzyme Inhibitors; Gene Expression Regulation; Humans; Indoles; Interleukin-1; Interleukin-6; Luciferases; Maleimides; Naphthalenes; Osteoblasts; Parathyroid Hormone; Phorbol 12,13-Dibutyrate; Promoter Regions, Genetic; Protein Kinase C; Rats; RNA, Messenger; Staurosporine; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2001 |
Inhibition of acetylcholine-activated K(+) current by chelerythrine and bisindolylmaleimide I in atrial myocytes from mice.
Topics: Acetylcholine; Alkaloids; Animals; Atrial Function; Benzophenanthridines; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Heart Atria; Indoles; Maleimides; Membrane Potentials; Mice; Naphthalenes; Patch-Clamp Techniques; Phenanthridines; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C | 2001 |
Protein kinase D is a downstream target of protein kinase Ctheta.
Topics: Alanine; Amino Acid Substitution; Animals; Catalytic Domain; COS Cells; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Jurkat Cells; Maleimides; Mutation; Phorbol 12,13-Dibutyrate; Precipitin Tests; Protein Kinase C; Protein Kinase C-theta; Serine; Signal Transduction; T-Lymphocytes; Transfection | 2002 |
Amyloid precursor protein processing is separately regulated by protein kinase C and tyrosine kinase in human astrocytes.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Astrocytes; Brain; Cells, Cultured; Drug Interactions; Enzyme Inhibitors; Fetus; Flavonoids; Genistein; Glial Fibrillary Acidic Protein; Humans; Indoles; Maleimides; MAP Kinase Signaling System; Phorbol 12,13-Dibutyrate; Platelet-Derived Growth Factor; Protein Kinase C; Protein-Tyrosine Kinases | 2002 |
Phorbol esters and adenosine affect the readily releasable neurotransmitter pool by different mechanisms at amphibian motor nerve endings.
Topics: Acetylcholine; Adenosine; Amphibians; Animals; Binomial Distribution; Calcium; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Evoked Potentials; Indoles; Maleimides; Monte Carlo Method; Nerve Endings; Neuromuscular Junction; Neurotransmitter Agents; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rana pipiens; Staurosporine; Synaptic Vesicles | 2003 |
Possible role of the protein kinase C/CPI-17 pathway in the augmented contraction of human myometrium after gestation.
Topics: Adult; Blotting, Western; Calcium; Carbazoles; Enzyme Activators; Enzyme Inhibitors; Female; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Maleimides; Muscle Contraction; Muscle Proteins; Myometrium; Myosin Light Chains; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Pregnancy; Pregnancy Trimester, Third; Protein Kinase C; RNA, Messenger; Serine; Type C Phospholipases; Uterine Contraction | 2003 |
Protein kinase C regulates functional coupling of beta1-adrenergic receptors to Gi/o-mediated responses in cardiac myocytes.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Animals; Calcium; Calcium Channels, L-Type; Electric Conductivity; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guinea Pigs; Histamine; Indoles; Maleimides; Myocytes, Cardiac; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Adrenergic, beta-1 | 2004 |
N-methyl-D-aspartate receptors enhance mechanical responses and voltage-dependent Ca2+ channels in rat dorsal root ganglia neurons through protein kinase C.
Topics: Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Ganglia, Spinal; Indoles; Intracellular Membranes; Maleimides; N-Methylaspartate; Neurons; Osmolar Concentration; Phorbol 12,13-Dibutyrate; Physical Stimulation; Protein Kinase C; Rats; Receptors, N-Methyl-D-Aspartate | 2004 |
Protein kinase C mediates the inhibitory effect of substance P on HCO3- secretion from guinea pig pancreatic ducts.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport; Enzyme Inhibitors; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Isoenzymes; Maleimides; Pancreatic Ducts; Perfusion; Phorbol 12,13-Dibutyrate; Protein Kinase C; Secretin; Sodium Bicarbonate; Substance P | 2005 |
PKC delta-isoform translocation and enhancement of tonic contractions of gastrointestinal smooth muscle.
Topics: Animals; Carbachol; Cytoplasm; Cytoskeleton; Diacylglycerol Kinase; Diterpenes; Female; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Isoenzymes; Male; Maleimides; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Transport; Scopolamine; Subcellular Fractions | 2007 |
Role of L-type calcium channels and PKC in active tone development in rabbit coronary artery.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcium Channel Blockers; Calcium Channels, L-Type; Carbazoles; Coronary Vessels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; In Vitro Techniques; Indoles; Male; Maleimides; Membrane Potentials; Nifedipine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phorbol 12,13-Dibutyrate; Pinacidil; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; Vasoconstriction; Vasodilator Agents | 2007 |
Mechanism of membrane redistribution of protein kinase C by its ATP-competitive inhibitors.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding, Competitive; Carbazoles; Cell Membrane; Chlorocebus aethiops; COS Cells; Diglycerides; Estrenes; HeLa Cells; HL-60 Cells; Humans; Indoles; Maleimides; Membranes; Microscopy, Confocal; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Transport; Pyrrolidinones; Staurosporine | 2007 |
Cytotoxic action of phorbol esters on human pancreatic cancer cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Inhibitory Concentration 50; Intracellular Signaling Peptides and Proteins; Maleimides; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Pancreatic Neoplasms; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Xenograft Model Antitumor Assays | 2007 |
Phorbol 12,13-dibutyrate-mediated contraction of the stimulated bronchial smooth muscles of mice.
Topics: Acetylcholine; Animals; Bronchi; Calcimycin; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; In Vitro Techniques; Indoles; Ionophores; Male; Maleimides; Mice; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Potassium; Smooth Muscle Myosins | 2010 |
Bioengineered human IAS reconstructs with functional and molecular properties similar to intact IAS.
Topics: Adrenergic beta-Agonists; Amides; Anal Canal; Bethanechol; Gene Expression Regulation, Enzymologic; Humans; Indoles; Isoproterenol; Maleimides; Muscarinic Agonists; Muscle Tonus; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Pyridines; rho-Associated Kinases; Tissue Engineering | 2012 |
Role of PKC and RhoA/ROCK pathways in the spontaneous phasic activity in the rectal smooth muscle.
Topics: Amides; Animals; Carcinogens; Enzyme Inhibitors; Fecal Incontinence; Indoles; Maleimides; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Rectum; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2013 |
Maternal high-salt diet altered PKC/MLC20 pathway and increased ANG II receptor-mediated vasoconstriction in adult male rat offspring.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Diet; Female; Indoles; Male; Maleimides; Maternal Nutritional Physiological Phenomena; Myosin Light Chains; Phorbol 12,13-Dibutyrate; Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Signal Transduction; Sodium; Sodium Chloride, Dietary; Vasoconstriction | 2016 |