phomactin-a and dichlorodicyanobenzoquinone

phomactin-a has been researched along with dichlorodicyanobenzoquinone* in 1 studies

Other Studies

1 other study(ies) available for phomactin-a and dichlorodicyanobenzoquinone

Article	Year
A total synthesis of (+/-)-phomactin A. Organic & biomolecular chemistry, 2003, Nov-21, Volume: 1, Issue:22 A total synthesis of the PAF antagonist phomactin A (1), isolated from the marine fungus Phoma sp. is described. The synthesis is based on a Cr(II)/Ni(II) macrocyclisation from the aldehyde vinyl iodide 14, leading to the key phomactatrienol intermediate 16a, followed by elaboration of 16a to the epoxyketone 21, which undergoes spontaneous pyran and hemiacetal ring formation to 1 on deprotection with DDQ. Topics: Aldehydes; Ascomycota; Benzoquinones; Chromium; Heterocyclic Compounds, 4 or More Rings; Ketones; Models, Chemical; Nickel; Platelet Activating Factor; Pyrans; Stereoisomerism	2003

Article

Year

Organic & biomolecular chemistry, 2003, Nov-21, Volume: 1, Issue:22

A total synthesis of the PAF antagonist phomactin A (1), isolated from the marine fungus Phoma sp. is described. The synthesis is based on a Cr(II)/Ni(II) macrocyclisation from the aldehyde vinyl iodide 14, leading to the key phomactatrienol intermediate 16a, followed by elaboration of 16a to the epoxyketone 21, which undergoes spontaneous pyran and hemiacetal ring formation to 1 on deprotection with DDQ.

Topics: Aldehydes; Ascomycota; Benzoquinones; Chromium; Heterocyclic Compounds, 4 or More Rings; Ketones; Models, Chemical; Nickel; Platelet Activating Factor; Pyrans; Stereoisomerism

2003