phloroglucinol and quercetin

phloroglucinol has been researched along with quercetin in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.41)18.7374
1990's8 (21.62)18.2507
2000's14 (37.84)29.6817
2010's12 (32.43)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Choi, JS; Jung, HA; Oh, SH1
Gates, DM; Ingledew, WM; Jones, GA; Tsai, CG1
Bryant, MP; Crawford, RL; Hemling, ME; Krumholz, LR1
Chatterjee, SS; Erdelmeier, C; Koch, E; Nöldner, M1
Hafner, U; Müller, WE; Rolli, M; Schäfer, C; Singer, A; Wonnemann, M1
Bhattacharya, SK; Chakrabarti, A; Chatterjee, SS1
Dimpfel, W; Mannel, M; Schober, F1
Biber, A; Chatterjee, SS; Fischer, H; Römer, A1
Dimpfel, W; Sauer, S; Schellenberg, R1
Baghai, T; Kieser, M; Laakmann, G; Schüle, C1
Bhattacharya, SK; Chatterjee, SS; Müller, WE; Singer, A; Wonnemann, M1
Obach, RS1
Chatterjee, S; Nöldner, M1
Coutts, RT; Gu, LD; Ling, L; Pang, PK; Shan, JJ; Sloley, BD; Urichuk, LJ1
Dressman, J; Kaunzinger, A; Schubert-Zsilavecz, M; Westerhoff, K; Wurglics, M1
Butterweck, V; Simbrey, K; Winterhoff, H1
Borrelli, F; Capasso, F; Capasso, R; Izzo, AA; Mascolo, N1
Fricker, G; Kressmann, S; Müller, WE; Weber, CC1
Bässler, D; Schulz, HU; Schürer, M; Weiser, D2
Albring, DV; Bernardi, AP; Bordignon, SA; Bridi, R; Dutra-Filho, CS; Ferraz, AB; Henriques, AT; Schripsema, J; von Poser, GL1
Cao, J; Chan, E; Chen, X; Duan, W; Hu, ZP; Huang, M; Wen, JY; Yang, XX; Yu, XQ; Zhou, SF1
Häberlein, H; Prenner, L; Sieben, A; Weiser, D; Zeller, K1
Dobryakov, YG; Eshchenko, AY; Makarova, SV; Utsal, VA; Vitenberg, AG; Zenkevich, IG1
Cirak, C; Ivanauskas, L; Janulis, V; Radusiene, J2
Gilani, AH; Khan, AU1
Arakawa, K; Fujikawa, S; Fukushi, Y; Inada, T; Kasuga, J; Koyama, T; Kuwabara, C; Wang, D1
Häberlein, H; Hage-Hülsmann, A; Jakobs, D; Kolb, C; Prenner, L; Weiser, D1
Ananda, S; Srilatha, BR1
Cho, JH; Cho, KK; Kang, SN; Kim, IS; Lee, JS; Lee, OH; Park, JH1
Arakawa, NS; Cardoso, RD; Casagrande, R; Fattori, V; Hohmann, MS; Lopes, NP; Tomaz, JC; Verri, WA1
Antognoni, F; Bonvicini, F; Cornioli, L; Fiorentino, A; Mandrone, M; Poli, F; Sanna, C; Scognamiglio, M1
Butterweck, V; Kalbhenn-Aziz, H; Kolb, C; Verjee, S; Weston, A1
Dresler, S; Kováčik, J; Sowa, I; Strzemski, M; Wójciak-Kosior, M1
Boonen, G; Bussmann, H; Drewe, J; Franken, S; Häberlein, H; Keksel, N; Unger, M1
Saçıcı, E; Yesilada, E1

Trials

5 trial(s) available for phloroglucinol and quercetin

ArticleYear
Oral bioavailability of hyperforin from hypericum extracts in rats and human volunteers.
    Pharmacopsychiatry, 1998, Volume: 31 Suppl 1

    Topics: Administration, Oral; Adult; Animals; Area Under Curve; Biological Availability; Bridged Bicyclo Compounds; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Hypericum; Male; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Rats; Rats, Sprague-Dawley; Terpenes; Xanthenes

1998
Pharmacodynamic effects of two different hypericum extracts in healthy volunteers measured by quantitative EEG.
    Pharmacopsychiatry, 1998, Volume: 31 Suppl 1

    Topics: Adult; Anthracenes; Bridged Bicyclo Compounds; Cerebral Cortex; Electroencephalography; Female; Humans; Hypericum; Male; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Terpenes; Xanthenes

1998
St. John's wort in mild to moderate depression: the relevance of hyperforin for the clinical efficacy.
    Pharmacopsychiatry, 1998, Volume: 31 Suppl 1

    Topics: Antidepressive Agents; Bridged Bicyclo Compounds; Depressive Disorder; Double-Blind Method; Female; Humans; Hypericum; Male; Middle Aged; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Terpenes; Xanthenes

1998
Investigation of the bioavailability of hypericin, pseudohypericin, hyperforin and the flavonoids quercetin and isorhamnetin following single and multiple oral dosing of a hypericum extract containing tablet.
    Arzneimittel-Forschung, 2005, Volume: 55, Issue:1

    Topics: Adolescent; Adult; Anthracenes; Antidepressive Agents; Area Under Curve; Biological Availability; Bridged Bicyclo Compounds; Flavonols; Humans; Hypericum; Male; Middle Aged; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Tablets; Terpenes

2005
Investigation of pharmacokinetic data of hypericin, pseudohypericin, hyperforin and the flavonoids quercetin and isorhamnetin revealed from single and multiple oral dose studies with a hypericum extract containing tablet in healthy male volunteers.
    Arzneimittel-Forschung, 2005, Volume: 55, Issue:10

    Topics: Adolescent; Adult; Anthracenes; Bridged Bicyclo Compounds; Flavonols; Humans; Hypericum; Male; Middle Aged; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Tablets; Terpenes

2005

Other Studies

32 other study(ies) available for phloroglucinol and quercetin

ArticleYear
Molecular docking studies of phlorotannins from Eisenia bicyclis with BACE1 inhibitory activity.
    Bioorganic & medicinal chemistry letters, 2010, Jun-01, Volume: 20, Issue:11

    Topics: Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Enzyme Inhibitors; Kinetics; Models, Molecular; Tannins

2010
Products of anaerobic phloroglucinol degradation by Coprococcus sp. Pe15.
    Canadian journal of microbiology, 1976, Volume: 22, Issue:2

    Topics: Acetates; Anaerobiosis; Animals; Bacteria; Biodegradation, Environmental; Carbon Dioxide; Fatty Acids, Volatile; Flavonoids; Phenols; Phloroglucinol; Quercetin; Rumen

1976
A rumen bacterium degrading quercetin and trihydroxybenzenoids with concurrent use of formate or H2.
    Progress in clinical and biological research, 1986, Volume: 213

    Topics: Animals; Bacteria; Flavonoids; Formates; Gallic Acid; Hydrogen; Phloroglucinol; Quercetin; Rumen

1986
Antidepressant activity of hypericum perforatum and hyperforin: the neglected possibility.
    Pharmacopsychiatry, 1998, Volume: 31 Suppl 1

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Bridged Bicyclo Compounds; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Guinea Pigs; Heart Rate; Hypericum; Ileum; In Vitro Techniques; Male; Muscle Contraction; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Terpenes; Xanthenes

1998
Hyperforin represents the neurotransmitter reuptake inhibiting constituent of hypericum extract.
    Pharmacopsychiatry, 1998, Volume: 31 Suppl 1

    Topics: Animals; Brain; Bridged Bicyclo Compounds; Dopamine; Female; Hypericum; Male; Mice; Monoamine Oxidase; Neurotransmitter Uptake Inhibitors; Norepinephrine; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Synaptosomes; Terpenes; Xanthenes

1998
Activity profiles of two hyperforin-containing hypericum extracts in behavioral models.
    Pharmacopsychiatry, 1998, Volume: 31 Suppl 1

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Body Temperature; Bridged Bicyclo Compounds; Hypericum; Male; Mice; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Rats; Stereotyped Behavior; Terpenes; Xanthenes

1998
Effects of a methanolic extract and a hyperforin-enriched CO2 extract of St. John's Wort (Hypericum perforatum) on intracerebral field potentials in the freely moving rat (Tele-Stereo-EEG).
    Pharmacopsychiatry, 1998, Volume: 31 Suppl 1

    Topics: Animals; Brain; Bridged Bicyclo Compounds; Carbon Dioxide; Electrodes, Implanted; Electroencephalography; Hypericum; Male; Methanol; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Rats; Terpenes; Xanthenes

1998
Hyperforin as a possible antidepressant component of hypericum extracts.
    Life sciences, 1998, Volume: 63, Issue:6

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Bridged Bicyclo Compounds; Helplessness, Learned; Hypericum; Male; Models, Chemical; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurotransmitter Uptake Inhibitors; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Rats; Synaptosomes; Terpenes; Xanthenes

1998
Inhibition of human cytochrome P450 enzymes by constituents of St. John's Wort, an herbal preparation used in the treatment of depression.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:1

    Topics: Anthracenes; Antidepressive Agents; Bridged Bicyclo Compounds; Chlorogenic Acid; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Hypericum; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Terpenes

2000
Effects of two different extracts of St. John's wort and some of their constituents on cytochrome P450 activities in rat liver microsomes.
    Pharmacopsychiatry, 2001, Volume: 34 Suppl 1

    Topics: Animals; Anthracenes; Antidepressive Agents; Bridged Bicyclo Compounds; Cytochrome P-450 Enzyme System; Ethanol; Excitatory Amino Acid Antagonists; Female; Hypericum; Liver; Male; Methanol; Microsomes; Perylene; Phenobarbital; Phloroglucinol; Plant Extracts; Quercetin; Rats; Rats, Sprague-Dawley; Sex Factors; Solvents; Terpenes

2001
Chemical and pharmacological evaluation of Hypericum perforatum extracts.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:12

    Topics: Animals; Anthracenes; Antioxidants; Bridged Bicyclo Compounds; Free Radical Scavengers; Hippocampus; Hypericum; Male; Perylene; Phloroglucinol; Quercetin; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Terpenes

2000
Biorelevant dissolution testing of St John's wort products.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:12

    Topics: Antidepressive Agents; Bridged Bicyclo Compounds; Capsules; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Ethanol; Hypericum; Kinetics; Methanol; Phloroglucinol; Plant Extracts; Quercetin; Reproducibility of Results; Rutin; Solubility; Solvents; Terpenes; Time Factors

2002
Extracts of St. John's wort and various constituents affect beta-adrenergic binding in rat frontal cortex.
    Life sciences, 2004, Jan-09, Volume: 74, Issue:8

    Topics: Animals; Anthracenes; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bridged Bicyclo Compounds; Cell Membrane; Fluoxetine; Frontal Lobe; Hypericum; Imipramine; Male; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Radioligand Assay; Rats; Receptors, Adrenergic, beta; Terpenes

2004
Inhibitory effect of the antidepressant St. John's wort (hypericum perforatum) on rat bladder contractility in vitro.
    Urology, 2004, Volume: 64, Issue:1

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Anthracenes; Antidepressive Agents; Atropine; Bridged Bicyclo Compounds; Capsaicin; Depression; Electric Stimulation; Female; Haloperidol; Hypericum; Kaempferols; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Naloxone; Perylene; Phentolamine; Phloroglucinol; Piperidines; Plant Extracts; Propranolol; Pyrazoles; Quercetin; Rats; Rats, Wistar; Rimonabant; Rutin; Terpenes; Tetrodotoxin; Urinary Bladder; Urinary Incontinence; Verapamil

2004
Modulation of P-glycoprotein function by St John's wort extract and its major constituents.
    Pharmacopsychiatry, 2004, Volume: 37, Issue:6

    Topics: Adenosine Triphosphate; Amitriptyline; Animals; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Bridged Bicyclo Compounds; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Endothelial Cells; Fluoresceins; Fluoxetine; Herb-Drug Interactions; Humans; Hypericum; Leukemia; Models, Biological; Phloroglucinol; Plant Extracts; Quercetin; Swine; Terpenes

2004
Benzophenones from Hypericum carinatum.
    Journal of natural products, 2005, Volume: 68, Issue:5

    Topics: Antioxidants; Benzophenones; Brazil; Dose-Response Relationship, Drug; Hypericum; Luminescent Measurements; Molecular Structure; Phloroglucinol; Plant Leaves; Plants, Medicinal; Quercetin

2005
A mechanistic study on altered pharmacokinetics of irinotecan by St. John's wort.
    Current drug metabolism, 2007, Volume: 8, Issue:2

    Topics: Animals; Anthracenes; Antineoplastic Agents, Phytogenic; Bridged Bicyclo Compounds; Camptothecin; Cell Line, Tumor; Cell Proliferation; Glucuronides; Hypericum; Irinotecan; Male; Microsomes, Liver; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Rats; Rats, Sprague-Dawley; Terpenes

2007
Reduction of high-affinity beta2-adrenergic receptor binding by hyperforin and hyperoside on rat C6 glioblastoma cells measured by fluorescence correlation spectroscopy.
    Biochemistry, 2007, May-01, Volume: 46, Issue:17

    Topics: Animals; Brain Neoplasms; Bridged Bicyclo Compounds; Cell Line, Tumor; Cyclic AMP; Glioblastoma; Humans; Phloroglucinol; Protein Binding; Quercetin; Rats; Receptors, Adrenergic, beta-2; Spectrometry, Fluorescence; Terpenes

2007
Identification of the products of oxidation of quercetin by air oxygen at ambient temperature.
    Molecules (Basel, Switzerland), 2007, Mar-27, Volume: 12, Issue:3

    Topics: Air; Chromatography, Gas; Chromatography, High Pressure Liquid; Decarboxylation; Dehydroascorbic Acid; Ketones; Oxidation-Reduction; Oxygen; Phloroglucinol; Quercetin; Spectrophotometry, Ultraviolet; Stereoisomerism; Temperature

2007
Chemical constituents of Hypericum adenotrichum Spach, an endemic Turkish species.
    Natural product research, 2009, Volume: 23, Issue:13

    Topics: Anthracenes; Bridged Bicyclo Compounds; Chromatography, High Pressure Liquid; Hypericum; Kaempferols; Perylene; Phloroglucinol; Quercetin; Terpenes; Turkey

2009
Secondary metabolites of Hypericum confertum and their possible chemotaxonomic significance.
    Natural product communications, 2010, Volume: 5, Issue:6

    Topics: Anthracenes; Apigenin; Biflavonoids; Bridged Bicyclo Compounds; Chlorogenic Acid; Hypericum; Perylene; Phloroglucinol; Plant Components, Aerial; Quercetin; Rutin; Terpenes

2010
Pharmacological studies on Hypericum perforatum fractions and constituents.
    Pharmaceutical biology, 2011, Volume: 49, Issue:1

    Topics: Animals; Anthracenes; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hypericum; In Vitro Techniques; Male; Perylene; Phloroglucinol; Phosphodiesterase Inhibitors; Plant Extracts; Quercetin; Rabbits; Terpenes; Verapamil

2011
Change of supercooling capability in solutions containing different kinds of ice nucleators by flavonol glycosides from deep supercooling xylem parenchyma cells in trees.
    Cryobiology, 2011, Volume: 63, Issue:3

    Topics: Cryoprotective Agents; Erwinia; Excipients; Freezing; Ice; Iodides; Kaempferols; Mesophyll Cells; Monosaccharides; Phloroglucinol; Quercetin; Silver Compounds; Solutions; Trees; Water; Xanthomonas campestris; Xylem

2011
Downregulation of β1 -adrenergic receptors in rat C6 glioblastoma cells by hyperforin and hyperoside from St John's wort.
    The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:6

    Topics: Animals; Cell Line, Tumor; Cell Membrane; Cyclic AMP; Down-Regulation; Glioblastoma; Hypericum; Phloroglucinol; Plant Extracts; Quercetin; Rats; Receptors, Adrenergic, beta-1; Terpenes

2013
Antidiabetic effects of Mukia maderaspatana and its phenolics: an in vitro study on gluconeogenesis and glucose uptake in rat tissues.
    Pharmaceutical biology, 2014, Volume: 52, Issue:5

    Topics: Animals; Chromatography, High Pressure Liquid; Cucurbitaceae; Diaphragm; Gluconeogenesis; Glucose; Hypoglycemic Agents; In Vitro Techniques; Liver; Male; Phenols; Phloroglucinol; Quercetin; Rats

2014
In vitro anti-osteoporosis properties of diverse Korean Drynariae rhizoma phenolic extracts.
    Nutrients, 2014, Apr-24, Volume: 6, Issue:4

    Topics: Animals; Antioxidants; Catechin; Cell Proliferation; Cells, Cultured; Chlorogenic Acid; Chromatography, High Pressure Liquid; Coumaric Acids; Emodin; Hydroxybenzoates; Luteolin; Mice; Osteoporosis; Phloroglucinol; Plant Extracts; Plants, Medicinal; Polypodiaceae; Quercetin; Republic of Korea

2014
Hypericum perforatum Reduces Paracetamol-Induced Hepatotoxicity and Lethality in Mice by Modulating Inflammation and Oxidative Stress.
    Phytotherapy research : PTR, 2015, Volume: 29, Issue:7

    Topics: Acetaminophen; Alanine Transaminase; Animals; Anthracenes; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glutathione; Hypericum; Inflammation; Male; Mice; Oxidative Stress; Perylene; Phloroglucinol; Plant Extracts; Plants, Medicinal; Quercetin; Rutin; Terpenes; Tumor Necrosis Factor-alpha

2015
Phytochemical profile and α-glucosidase inhibitory activity of Sardinian Hypericum scruglii and Hypericum hircinum.
    Fitoterapia, 2017, Volume: 120

    Topics: Animals; Antioxidants; Chlorocebus aethiops; Glycoside Hydrolase Inhibitors; Hypericum; Italy; Phloroglucinol; Phytochemicals; Plant Components, Aerial; Plant Extracts; Quercetin; Vero Cells

2017
Hyperforin and Miquelianin from St. John's Wort Attenuate Gene Expression in Neuronal Cells After Dexamethasone-Induced Stress.
    Planta medica, 2018, Volume: 84, Issue:9-10

    Topics: Biomarkers; Cell Line; Dexamethasone; Gene Expression Regulation; Glucosides; Humans; Hypericum; Neurons; Phloroglucinol; Quercetin; Stress, Physiological; Terpenes

2018
Methodological aspects of biologically active compounds quantification in the genus Hypericum.
    Journal of pharmaceutical and biomedical analysis, 2018, Jun-05, Volume: 155

    Topics: Anthracenes; Catechin; Chlorogenic Acid; Chromatography, High Pressure Liquid; Hypericum; Perylene; Phloroglucinol; Plant Extracts; Plant Leaves; Plant Stems; Quercetin; Rutin; Terpenes

2018
St John's wort extract influences membrane fluidity and composition of phosphatidylcholine and phosphatidylethanolamine in rat C6 glioblastoma cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Feb-15, Volume: 54

    Topics: Animals; Anthracenes; Cell Line, Tumor; Cell Membrane; Glioblastoma; Hydrocortisone; Hypericum; Membrane Fluidity; Perylene; Phloroglucinol; Phosphatidylethanolamines; Plant Extracts; Quercetin; Rats; Receptors, Adrenergic, beta-1; Signal Transduction; Terpenes

2019
Development of new and validated HPTLC methods for the qualitative and quantitative analysis of hyperforin, hypericin and hyperoside contents in Hypericum species.
    Phytochemical analysis : PCA, 2022, Volume: 33, Issue:3

    Topics: Anthracenes; Chromatography, Thin Layer; Hypericum; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Terpenes

2022