phloroglucinol and myrtucommulone a

phloroglucinol has been researched along with myrtucommulone a in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's0 (0.00)18.2507
2000's6 (26.09)29.6817
2010's16 (69.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Appendino, G; Ballero, M; Bianchi, F; Gibbons, S; Minassi, A; Sterner, O1
Kashman, Y; Lifshitz, A; Rotstein, A1
Appendino, G; Feisst, C; Franke, L; Werz, O1
Blaesius, D; Cinatl, J; Maxia, L; Michaelis, M; Schulze-Osthoff, K; Tretiakova, I; Werz, O; Wesselborg, S1
Carroll, AR; Forster, PI; Guymer, GP; Lamb, J; Moni, R; Quinn, RJ1
Bramanti, P; Caminiti, R; Cuzzocrea, S; Di Paola, R; Genovese, T; Koeberle, A; Mazzon, E; Pergola, C; Rossi, A; Sautebin, L; Werz, O1
Koeberle, A; Northoff, H; Pollastro, F; Werz, O1
Blaesius, D; Hartmann, D; Huch, V; Jauch, J; Koeberle, A; Müller, H; Paul, M; Werz, O1
Abdel-Tawab, M; Gerbeth, K; Meins, J; Schubert-Zsilavecz, M; Werz, O1
Ambonati, M; Aries, MF; Degouy, A; Fabre, B; Fiorini-Puybaret, C; Luc, J; Mamatas, S; Mejean, C; Poli, F1
Busonera, B; Caboni, P; Casu, L; Cottiglia, F; Farci, P; Floris, C; Leonti, M; Ouhtit, A; Sanna, G1
Abdel-Tawab, M; Barrett, JS; Gerbeth, K; Hüsch, J; Meins, J; Rossi, A; Sautebin, L; Schubert-Zsilavecz, M; Skarke, C; Werz, O; Wiechmann, K1
Dicato, M; Diederich, M; Grandjenette, C; Mack, F; Morceau, F; Schnekenburger, M; Werz, O; Wiechmann, K1
Canatan, H; Iskender, B; Izgi, K; Karaca, H1
Canatan, H; Iskender, B; Izgi, K; Sakalar, C1
Fischer, D; Jauch, J; Müller, H; Werz, O; Wiechmann, K1
Bringmann, G; Bruhn, T; Charpentier, M; Hans, M; Huch, V; Jauch, J; Quandt, D1
Arslanhan, A; Canatan, H; Hizar, E; Iskender, B; Izgi, K; Jauch, J; Yuksek, EH1
Canatan, H; Iskender, B; Izgi, K1
Arslanhan, A; Canatan, H; Hizar, E; Iskender, B; Izgi, K; Sakalar, C; Yuksek, EH1
Jauch, J; König, S; Müller, H; Svatoš, A; Werz, O; Wiechmann, K; Wielsch, N1
Suzuki, CK; Venkatesh, S1
Andolfi, A; Ferranti, P; Nicoletti, R; Salvatore, MM1

Reviews

1 review(s) available for phloroglucinol and myrtucommulone a

ArticleYear
Structures and Bioactive Properties of Myrtucommulones and Related Acylphloroglucinols from Myrtaceae.
    Molecules (Basel, Switzerland), 2018, Dec-19, Volume: 23, Issue:12

    Topics: Myrtaceae; Myrtus; Phloroglucinol; Plant Extracts

2018

Other Studies

22 other study(ies) available for phloroglucinol and myrtucommulone a

ArticleYear
Oligomeric acylphloroglucinols from myrtle (Myrtus communis).
    Journal of natural products, 2002, Volume: 65, Issue:3

    Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Drug Resistance, Microbial; Italy; Mass Spectrometry; Molecular Structure; Myrtaceae; Nuclear Magnetic Resonance, Biomolecular; Phloroglucinol; Plant Leaves; Plants, Medicinal; Structure-Activity Relationship

2002
Isolation and antibacterial activity of acylphloroglucinols from Myrtus communis.
    Antimicrobial agents and chemotherapy, 1974, Volume: 6, Issue:5

    Topics: Anti-Bacterial Agents; Bacteria; Myrtus; Phloroglucinol

1974
Identification of molecular targets of the oligomeric nonprenylated acylphloroglucinols from Myrtus communis and their implication as anti-inflammatory compounds.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:1

    Topics: Anti-Inflammatory Agents; Calcium; Cyclooxygenase Inhibitors; GTP-Binding Proteins; Humans; Leukocyte Elastase; Lipoxygenase Inhibitors; Phloroglucinol; Reactive Oxygen Species

2005
Myrtucommulone from Myrtus communis induces apoptosis in cancer cells via the mitochondrial pathway involving caspase-9.
    Apoptosis : an international journal on programmed cell death, 2008, Volume: 13, Issue:1

    Topics: Apoptosis; Caspase 9; Caspases; Cell Line, Tumor; Cell Survival; Cytochromes c; DNA Fragmentation; HL-60 Cells; Humans; Leukocytes, Mononuclear; Membrane Potential, Mitochondrial; Mitochondria; Nucleosomes; Phloroglucinol; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases

2008
Myrtucommulones F-I, phloroglucinols with thyrotropin-releasing hormone receptor-2 binding affinity from the seeds of Corymbia scabrida.
    Journal of natural products, 2008, Volume: 71, Issue:9

    Topics: Animals; Molecular Structure; Myrtaceae; Phloroglucinol; Plants, Medicinal; Queensland; Rats; Receptors, Thyrotropin-Releasing Hormone; Seeds

2008
Myrtucommulone from Myrtus communis exhibits potent anti-inflammatory effectiveness in vivo.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Carrageenan; Cyclooxygenase 2; Cytokines; Dinoprostone; Edema; Foot; Immunohistochemistry; Intercellular Adhesion Molecule-1; Interleukin-1beta; Leukotriene B4; Lipid Peroxidation; Male; Mice; Myrtus; P-Selectin; Peroxidase; Phloroglucinol; Pleurisy; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha

2009
Myrtucommulone, a natural acylphloroglucinol, inhibits microsomal prostaglandin E(2) synthase-1.
    British journal of pharmacology, 2009, Volume: 156, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Fatty Acids, Unsaturated; Humans; Intramolecular Oxidoreductases; Microsomes; Phloroglucinol; Prostaglandin-E Synthases

2009
Total synthesis of myrtucommulone A.
    Angewandte Chemie (International ed. in English), 2010, Mar-08, Volume: 49, Issue:11

    Topics: Anti-Inflammatory Agents; Apoptosis; Crystallography, X-Ray; Molecular Conformation; Myrtus; Phloroglucinol

2010
Determination of myrtucommulone from Myrtus communis in human and rat plasma by liquid chromatography/tandem mass spectrometry.
    Planta medica, 2011, Volume: 77, Issue:5

    Topics: Animals; Chromatography, Liquid; Drug Stability; Humans; Myrtus; Phloroglucinol; Rats; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2011
Pharmacological properties of Myrtacine® and its potential value in acne treatment.
    Planta medica, 2011, Volume: 77, Issue:14

    Topics: Acne Vulgaris; Anti-Bacterial Agents; Anti-Inflammatory Agents; Cyclooxygenase 2; Dose-Response Relationship, Drug; Humans; Keratinocytes; Lipase; Microbial Sensitivity Tests; Myrtus; Phloroglucinol; Plant Extracts; Plant Leaves; Propionibacterium acnes

2011
Cytotoxic phloroglucinols from the leaves of Myrtus communis.
    Journal of natural products, 2012, Feb-24, Volume: 75, Issue:2

    Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Italy; Microbial Sensitivity Tests; Molecular Structure; Myrtus; Phloroglucinol; Plant Leaves; Staphylococcus aureus

2012
Myrtucommulone from Myrtus communis: metabolism, permeability, and systemic exposure in rats.
    Planta medica, 2012, Volume: 78, Issue:18

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Biological Availability; Caco-2 Cells; Drug Stability; Humans; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Male; Microsomes, Liver; Molecular Structure; Myrtus; Permeability; Phloroglucinol; Prostaglandin-E Synthases; Rats; Rats, Wistar

2012
Dual induction of mitochondrial apoptosis and senescence in chronic myelogenous leukemia by myrtucommulone A.
    Anti-cancer agents in medicinal chemistry, 2015, Volume: 15, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Cell Survival; Cellular Senescence; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mitochondria; Molecular Structure; Phloroglucinol; Structure-Activity Relationship; Tumor Cells, Cultured; U937 Cells

2015
Myrtucommulone-A treatment decreases pluripotency- and multipotency-associated marker expression in bladder cancer cell line HTB-9.
    Journal of natural medicines, 2015, Volume: 69, Issue:4

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression; Humans; Immunohistochemistry; Phloroglucinol; Urinary Bladder Neoplasms

2015
Priming hMSCs with a putative anti-cancer compound, myrtucommulone-a: a way to harness hMSC cytokine expression via modulating PI3K/Akt pathway?
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:2

    Topics: Animals; Antineoplastic Agents; Benzoquinones; Blotting, Western; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Culture Media, Conditioned; Cytokines; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Immunohistochemistry; Mesenchymal Stem Cells; Mice; Phloroglucinol; Phosphatidylinositol 3-Kinases; Polymerase Chain Reaction; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Microenvironment

2016
The acylphloroglucinols hyperforin and myrtucommulone A cause mitochondrial dysfunctions in leukemic cells by direct interference with mitochondria.
    Apoptosis : an international journal on programmed cell death, 2015, Volume: 20, Issue:11

    Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Apoptosis; HL-60 Cells; Humans; Leukemia; Membrane Potential, Mitochondrial; Mitochondria; Phloroglucinol; Terpenes

2015
Stereoisomeric Composition of Natural Myrtucommulone A.
    Journal of natural products, 2015, Oct-23, Volume: 78, Issue:10

    Topics: Circular Dichroism; Electron Spin Resonance Spectroscopy; Germany; Molecular Structure; Myrtus; Phloroglucinol; Plant Leaves; Stereoisomerism

2015
Inhibition of epithelial-mesenchymal transition in bladder cancer cells via modulation of mTOR signalling.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:6

    Topics: Antineoplastic Agents; Benzoquinones; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colony-Forming Units Assay; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Phloroglucinol; Signal Transduction; TOR Serine-Threonine Kinases; Urinary Bladder Neoplasms; Wound Healing

2016
Novel anti-cancer agent myrtucommulone-A and thymoquinone abrogate epithelial-mesenchymal transition in cancer cells mainly through the inhibition of PI3K/AKT signalling axis.
    Molecular and cellular biochemistry, 2016, Volume: 416, Issue:1-2

    Topics: Benzoquinones; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Female; Humans; Male; Neoplasms; Phloroglucinol; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction

2016
Effects of Epirubicin and Cisplatin Against 4T1 Breast Cancer Cells are Enhanced by Myrtucommulone-A.
    Anti-cancer agents in medicinal chemistry, 2017, Volume: 17, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis Regulatory Proteins; Cell Proliferation; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Epirubicin; Mice; Molecular Structure; Phloroglucinol; Structure-Activity Relationship; Tumor Cells, Cultured; Wound Healing

2017
Mitochondrial Chaperonin HSP60 Is the Apoptosis-Related Target for Myrtucommulone.
    Cell chemical biology, 2017, May-18, Volume: 24, Issue:5

    Topics: Apoptosis; Chaperonin 60; Cytochromes c; Drug Design; Heat-Shock Response; HL-60 Cells; Humans; Mitochondria; Mitochondrial Proteins; Molecular Targeted Therapy; Phloroglucinol; Protein Aggregates

2017
HSP60 Takes a Hit: Inhibition of Mitochondrial Protein Folding.
    Cell chemical biology, 2017, May-18, Volume: 24, Issue:5

    Topics: Antineoplastic Agents; Chaperonin 60; Mitochondrial Proteins; Phloroglucinol; Protein Folding

2017