Compounds > phlorofucofuroeckol a

Page last updated: 2024-09-03

phlorofucofuroeckol a and dieckol

phlorofucofuroeckol a has been researched along with dieckol in 13 studies

Compound Research Comparison

Studies (phlorofucofuroeckol a)	Trials (phlorofucofuroeckol a)	Recent Studies (post-2010) (phlorofucofuroeckol a)	Studies (dieckol)	Trials (dieckol)	Recent Studies (post-2010) (dieckol)
30	0	22	97	2	82

Protein Interaction Comparison

Protein	Taxonomy	phlorofucofuroeckol a (IC50)	dieckol (IC50)
Replicase polyprotein 1ab	Severe acute respiratory syndrome-related coronavirus		2.7
Beta-secretase 1	Homo sapiens (human)		2.21

Research

Studies (13)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (15.38)	29.6817
2010's	8 (61.54)	24.3611
2020's	3 (23.08)	2.80

Authors

Authors	Studies
Kim, MM; Kim, SK; Lee, SH; Li, Y; Qian, ZJ; Ryu, B	1
Choi, JS; Jung, HA; Oh, SH	1
Jeong, HJ; Kim, D; Kim, JH; Kim, YM; Kwon, HJ; Kwon, JM; Lee, WS; Park, JY; Ryu, YB	1
Cao, W; Jian, Y; Ju, X; Li, H; Liang, C; Liu, H; Liu, Y; Ren, X; Tian, L; Wang, Y; Xie, X; Xin, L; Zhang, D; Zhao, Q	1
Bao, HY; Kang, JS; Lee, BH; Myung, CS; Shin, HC; Yeo, SJ	1
Choi, JS; Goo, HR; Na, DH	1
Cho, Y; Ito, H; Kondo, S; Konoki, K; Lin, YC; Segawa, S; Toyohara, H; Uchida, T; Yotsu-Yamashita, M	1
Kim, CG; Kim, TW; Kwon, TH; Park, NH	1
Bangoura, I; Cho, JY; Choi, YS; Chowdhury, MT; Hong, YK; Hwang, DS; Joo, J; Kang, JY	1
Kim, JS; Kim, T; Kwon, OJ; Kwon, TH; Park, KT; Park, NH; Seo, HJ; Woo, JH; Wu, YX	1
Choi, JS; Jung, HA; Paudel, P; Seong, SH	1
Choi, JS; Jung, HA; Park, SE; Paudel, P; Ryu, JH; Seong, SH	1
Han, SH; Kim, BG; Kim, MK; Lee, JH; Oh, SH; Park, MK; Park, S; Shin, HC; Suh, MW; Woo, H	1

Reviews

1 review(s) available for phlorofucofuroeckol a and dieckol

Article	Year
The development of Coronavirus 3C-Like protease (3CL European journal of medicinal chemistry, 2020, Nov-15, Volume: 206 Topics: Antiviral Agents; Coronavirus 3C Proteases; Cysteine Endopeptidases; Humans; Peptidomimetics; Protease Inhibitors; Viral Nonstructural Proteins	2020

Other Studies

12 other study(ies) available for phlorofucofuroeckol a and dieckol

Article	Year
Chemical components and its antioxidant properties in vitro: an edible marine brown alga, Ecklonia cava. Bioorganic & medicinal chemistry, 2009, Mar-01, Volume: 17, Issue:5 Topics: Animals; Antioxidants; Cell Line; Dioxins; Free Radical Scavengers; HL-60 Cells; Humans; Mice; Phaeophyceae; Reactive Oxygen Species; Sterols; Structure-Activity Relationship; Tannins	2009
Molecular docking studies of phlorotannins from Eisenia bicyclis with BACE1 inhibitory activity. Bioorganic & medicinal chemistry letters, 2010, Jun-01, Volume: 20, Issue:11 Topics: Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Enzyme Inhibitors; Kinetics; Models, Molecular; Tannins	2010
Dieckol, a SARS-CoV 3CL(pro) inhibitor, isolated from the edible brown algae Ecklonia cava. Bioorganic & medicinal chemistry, 2013, Jul-01, Volume: 21, Issue:13 Topics: Antiviral Agents; Benzofurans; Cysteine Proteases; Cysteine Proteinase Inhibitors; Humans; Molecular Docking Simulation; Phaeophyceae; Quantitative Structure-Activity Relationship; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus	2013
Improvement of memory by dieckol and phlorofucofuroeckol in ethanol-treated mice: possible involvement of the inhibition of acetylcholinesterase. Archives of pharmacal research, 2005, Volume: 28, Issue:6 Topics: Acetylcholinesterase; Animals; Benzofurans; Brain; Brain Chemistry; Cerebral Cortex; Cholinesterase Inhibitors; Corpus Striatum; Dioxins; Dose-Response Relationship, Drug; Ethanol; Hippocampus; Magnetic Resonance Spectroscopy; Male; Memory; Mice; Mice, Inbred ICR; Molecular Structure; Neurotransmitter Agents; Norepinephrine; Phaeophyceae	2005
Quantitative determination of major phlorotannins in Ecklonia stolonifera. Archives of pharmacal research, 2010, Volume: 33, Issue:4 Topics: Benzofurans; Chromatography, High Pressure Liquid; Dioxins; Phaeophyceae; Plants, Medicinal; Spectrometry, Mass, Electrospray Ionization; Tannins	2010
Isolation and structural determination of two novel phlorotannins from the brown alga Ecklonia kurome Okamura, and their radical scavenging activities. Marine drugs, 2013, Jan-18, Volume: 11, Issue:1 Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; Benzofurans; Biphenyl Compounds; Cell Line; Cell Line, Tumor; Dioxins; Fluoresceins; Free Radical Scavengers; Humans; Mass Spectrometry; Mice; Phaeophyceae; Phloroglucinol; Picrates; Polyphenols; Tannins	2013
Antioxidant activity of various solvent fractions from edible brown alga, Eisenia bicyclis and its active compounds. Journal of food science, 2013, Volume: 78, Issue:5 Topics: Antioxidants; Benzofurans; Benzothiazoles; Biphenyl Compounds; Dioxins; Free Radical Scavengers; Magnetic Resonance Spectroscopy; Oxidative Stress; Phaeophyceae; Picrates; Polyphenols; Reactive Oxygen Species; Solvents; Sulfonic Acids	2013
Comparison of Ecklonia cava, Ecklonia stolonifera and Eisenia bicyclis for phlorotannin extraction. Journal of environmental biology, 2014, Volume: 35, Issue:4 Topics: Benzofurans; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Dioxins; Models, Biological; Oxidation-Reduction; Phaeophyceae; Regression Analysis; Species Specificity	2014
6,6'-Bieckol inhibits adipocyte differentiation through downregulation of adipogenesis and lipogenesis in 3T3-L1 cells. Journal of the science of food and agriculture, 2015, Volume: 95, Issue:9 Topics: 3T3-L1 Cells; Adipogenesis; Animals; Anti-Obesity Agents; Benzofurans; Carbon-Carbon Ligases; Cell Survival; Dioxins; Down-Regulation; Fatty Acid Synthase, Type I; Lipid Metabolism; Mice; Molecular Structure; Pacific Ocean; Phaeophyceae; PPAR gamma; Republic of Korea; Seaweed; Stereoisomerism	2015
Identifying Phlorofucofuroeckol-A as a Dual Inhibitor of Amyloid-β Marine drugs, 2019, Oct-23, Volume: 17, Issue:11 Topics: Amyloid beta-Peptides; Benzofurans; Dioxins; Glycation End Products, Advanced; Lipid Peroxidation; Molecular Docking Simulation; Molecular Structure; Phaeophyceae; Phloroglucinol; Protein Aggregation, Pathological	2019
In Vitro and In Silico Characterization of G-Protein Coupled Receptor (GPCR) Targets of Phlorofucofuroeckol-A and Dieckol. Marine drugs, 2021, Jun-04, Volume: 19, Issue:6 Topics: Animals; Benzofurans; Cell Line; CHO Cells; Computer Simulation; Cricetulus; Dioxins; HeLa Cells; Humans; Mice; Molecular Docking Simulation; Phaeophyceae; Rats; Receptors, G-Protein-Coupled	2021
Effect of Phlorofucofuroeckol A and Dieckol Extracted from Marine drugs, 2021, Aug-01, Volume: 19, Issue:8 Topics: Animals; Antioxidants; Aquatic Organisms; Benzofurans; Cochlea; Dioxins; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Kelp; Male; Mice; Mice, Inbred C57BL; Phytotherapy; Plant Extracts	2021