Page last updated: 2024-08-16

phloretin and quercetin

phloretin has been researched along with quercetin in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.67)18.7374
1990's3 (10.00)18.2507
2000's12 (40.00)29.6817
2010's12 (40.00)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Constantinou, A; Mehta, R; Moon, R; Rao, K; Runyan, C; Vaughan, A1
Bröer, A; Bröer, S; Deitmer, JW; Halestrap, AP; Schneider, HP; Stegen, C1
Morris, ME; Nguyen, H; Zhang, S1
Morris, ME; Yang, X; Zhang, S1
Campitelli, MR; McArdle, BM; Quinn, RJ1
Domina, NG; Khlebnikov, AI; Kirpotina, LN; Quinn, MT; Schepetkin, IA1
Amić, D; Lucić, B1
Maccari, R; Ottanà, R1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Bicknell, KA; Farrimond, JA; Putnam, SE; Swioklo, S; Watson, KA; Williamson, EM1
Abe, H; Adachi, I; Horino, Y; Kesamaru, H; Nose, T; Suyama, K; Tomohara, K1
Grosman, N1
Burr, JG; Linder, ME; Van Wart-Hood, JE1
Bock, A; Eisenmann, M; Krischer, SM; Mueller, MJ1
Godejohann, M; Hollman, PC; Lommen, A; Spraul, M; Venema, DP1
Besson, C; Crespy, V; Démigné, C; Manach, C; Morand, C; Rémésy, C1
Bennett, RN; DuPont, MS; Mellon, FA; Williamson, G1
Afzal-Ahmed, I; Cunningham, P; Naftalin, RJ1
Gallegos, MT; Krell, T; Ramos, JL; Terán, W1
Cooney, JM; Jensen, DJ; Stevenson, DE; Wibisono, R; Zhang, J1
Chen, YY; Li, SH; Wu, XJ; Yang, QD; Zhou, N1
Ackermann, M; Hecker, D; Huemmer, W; Kahle, K; Kautenburger, T; Kempf, M; Richling, E; Scheppach, W; Schreier, P; Schrenk, D1
Al-Hasani, H; Corpe, CP; Eck, P; Levine, M; Wang, J1
Chulkov, EG; Ostroumova, OS1
Hübner, F; Humpf, HU; Saenger, T1
Jones, RS; Morris, ME; Parker, MD1
Aguiñiga-Sánchez, I; Aguirre-Medina, JF; Cadena-Iñiguez, J; Rivera-Martínez, AR; Ruiz-Posadas, LDM; Salazar-Aguilar, S; Santiago-Osorio, E; Soto-Hernández, M1
Eliopoulos, E; Papakonstantinou, E; Thireou, T; Vlachakis, D; Vlachoyiannopoulos, PG1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1

Trials

1 trial(s) available for phloretin and quercetin

ArticleYear
Short-term biomarkers of apple consumption.
    Molecular nutrition & food research, 2017, Volume: 61, Issue:3

    Topics: Adult; Biflavonoids; Biomarkers; Catechin; Chromatography, High Pressure Liquid; Female; Germany; Humans; Male; Malus; Phloretin; Proanthocyanidins; Quercetin; Reproducibility of Results; Tandem Mass Spectrometry

2017

Other Studies

29 other study(ies) available for phloretin and quercetin

ArticleYear
Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships.
    Journal of natural products, 1995, Volume: 58, Issue:2

    Topics: DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Electrophoresis, Agar Gel; Flavonoids; Hydroxylation; Plasmids; Protein Conformation; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1995
Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes.
    The Biochemical journal, 1999, Aug-01, Volume: 341 ( Pt 3)

    Topics: Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA Primers; Female; Hydrogen-Ion Concentration; Lactic Acid; Monocarboxylic Acid Transporters; Oocytes; Rats; Substrate Specificity; Xenopus laevis

1999
Effect of flavonoids on MRP1-mediated transport in Panc-1 cells.
    Journal of pharmaceutical sciences, 2003, Volume: 92, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Blotting, Western; Chemokines, CC; Daunorubicin; Flavonoids; Glutathione; Glutathione Transferase; Humans; Neoplasm Proteins; Tumor Cells, Cultured; Vinblastine

2003
Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport.
    Molecular pharmacology, 2004, Volume: 65, Issue:5

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Division; Chemokines, CC; Dose-Response Relationship, Drug; Drug Interactions; Flavonoids; Humans; Mitoxantrone; Neoplasm Proteins; Tumor Cells, Cultured

2004
A common protein fold topology shared by flavonoid biosynthetic enzymes and therapeutic targets.
    Journal of natural products, 2006, Volume: 69, Issue:1

    Topics: Biological Products; Flavonoids; Models, Molecular; Molecular Structure; Piperidines; Plants, Medicinal; Protein Conformation; Protein Folding; Protein Kinase Inhibitors; Proteins

2006
Improved quantitative structure-activity relationship models to predict antioxidant activity of flavonoids in chemical, enzymatic, and cellular systems.
    Bioorganic & medicinal chemistry, 2007, Feb-15, Volume: 15, Issue:4

    Topics: Animals; Antioxidants; Drug Design; Flavonoids; Humans; Phagocytes; Phenols; Polyphenols; Quantitative Structure-Activity Relationship

2007
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics

2010
Low molecular weight phosphotyrosine protein phosphatases as emerging targets for the design of novel therapeutic agents.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Antineoplastic Agents; Antitubercular Agents; Diabetes Mellitus; Humans; Hypoglycemic Agents; Insulin Resistance; Isoenzymes; Models, Molecular; Molecular Targeted Therapy; Mycobacterium tuberculosis; Neoplasms; Protein Conformation; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins

2012
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
    Journal of natural products, 2015, Nov-25, Volume: 78, Issue:11

    Topics: Cell Differentiation; Flavonoids; Humans; Mesenchymal Stem Cells; Molecular Structure; Osteogenesis; Signal Transduction; Structure-Activity Relationship

2015
DMSO-Perturbing Assay for Identifying Promiscuous Enzyme Inhibitors.
    ACS medicinal chemistry letters, 2019, Jun-13, Volume: 10, Issue:6

    Topics:

2019
Inhibitory effect of phloretin on histamine release from isolated rat mast cells.
    Agents and actions, 1988, Volume: 25, Issue:3-4

    Topics: Animals; Calcimycin; Histamine Release; Male; Mast Cells; Phloretin; Quercetin; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1988
TPCK and quercetin act synergistically with vanadate to increase protein-tyrosine phosphorylation in avian cells.
    Oncogene, 1989, Volume: 4, Issue:10

    Topics: Amino Acid Chloromethyl Ketones; Animals; Avian Sarcoma Viruses; Chick Embryo; Drug Synergism; Flavonoids; Oncogene Protein pp60(v-src); Phloretin; Phosphorylation; Proteins; Quercetin; Serine Proteinase Inhibitors; Tosylphenylalanyl Chloromethyl Ketone; Trifluoperazine; Tyrosine; Vanadates

1989
Protein-facilitated export of arachidonic acid from pig neutrophils.
    The Journal of biological chemistry, 1997, Apr-18, Volume: 272, Issue:16

    Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calorimetry; Cell Fractionation; Ethylmaleimide; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kinetics; Leukotriene A4; Leukotriene B4; Neutrophils; Phagocytosis; Phagosomes; Phloretin; Potassium; Quercetin; Sodium; Swine; Temperature

1997
Application of directly coupled HPLC-NMR-MS to the identification and confirmation of quercetin glycosides and phloretin glycosides in apple peel.
    Analytical chemistry, 2000, Apr-15, Volume: 72, Issue:8

    Topics: Chromatography, High Pressure Liquid; Glycosides; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phloretin; Quercetin; Rosales; Spectrophotometry, Ultraviolet

2000
Comparison of the intestinal absorption of quercetin, phloretin and their glucosides in rats.
    The Journal of nutrition, 2001, Volume: 131, Issue:8

    Topics: Animals; Antidiarrheals; Glucosides; Intestinal Absorption; Intestine, Small; Perfusion; Phloretin; Phlorhizin; Quercetin; Rats; Rats, Wistar

2001
Polyphenols from alcoholic apple cider are absorbed, metabolized and excreted by humans.
    The Journal of nutrition, 2002, Volume: 132, Issue:2

    Topics: Absorption; Adult; Alcoholic Beverages; Caffeic Acids; Chromatography, High Pressure Liquid; Female; Flavonoids; Hippurates; Humans; Male; Malus; Methylation; Phenols; Phloretin; Polymers; Quercetin

2002
Docking studies show that D-glucose and quercetin slide through the transporter GLUT1.
    The Journal of biological chemistry, 2006, Mar-03, Volume: 281, Issue:9

    Topics: Binding Sites; Biological Transport; Erythrocytes; Glucose; Glucose Transporter Type 1; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Mutation; Phloretin; Protein Conformation; Quercetin

2006
Effector-repressor interactions, binding of a single effector molecule to the operator-bound TtgR homodimer mediates derepression.
    The Journal of biological chemistry, 2006, Mar-17, Volume: 281, Issue:11

    Topics: Anti-Infective Agents; Bacterial Proteins; beta-Galactosidase; Calorimetry; Chloramphenicol; Dimerization; Drug Resistance, Multiple; Entropy; Evolution, Molecular; Flavonoids; Gene Expression Regulation, Bacterial; Hot Temperature; Kinetics; Models, Chemical; Models, Molecular; Naphthols; Operator Regions, Genetic; Parabens; Phloretin; Plasmids; Polymerase Chain Reaction; Protein Binding; Protein Conformation; Pseudomonas putida; Quercetin; Repressor Proteins; Solvents; Structure-Activity Relationship; Temperature; Thermodynamics; Time Factors; Transcription, Genetic

2006
Comparison of the relative recovery of polyphenolics in two fruit extracts from a model of degradation during digestion and metabolism.
    Molecular nutrition & food research, 2007, Volume: 51, Issue:8

    Topics: Anthocyanins; Blueberry Plants; Chlorogenic Acid; Digestion; Flavonoids; Fruit; Glucuronides; Hydrogen-Ion Concentration; Hydrolysis; Malus; Models, Biological; Phenols; Phloretin; Plant Extracts; Polyphenols; Quercetin; Species Specificity

2007
[Studies on the chemical constituents of Lithocarpus polystachyus].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:4

    Topics: Antioxidants; Chromatography, Thin Layer; Fagaceae; Luteolin; Oleanolic Acid; Phloretin; Plant Leaves; Quercetin; Sitosterols; Spectroscopy, Fourier Transform Infrared

2010
Intestinal transit and systemic metabolism of apple polyphenols.
    European journal of nutrition, 2011, Volume: 50, Issue:7

    Topics: Adult; Animals; Beverages; Biflavonoids; Caffeic Acids; Catechin; Chromatography, Gas; Chromatography, High Pressure Liquid; Coumaric Acids; Female; Gastrointestinal Transit; Hepatocytes; Humans; Ileostomy; Intestinal Mucosa; Male; Malus; Phloretin; Polyphenols; Proanthocyanidins; Quercetin; Quinic Acid; Rats; Rats, Wistar; Saliva; Tandem Mass Spectrometry; Young Adult

2011
Intestinal dehydroascorbic acid (DHA) transport mediated by the facilitative sugar transporters, GLUT2 and GLUT8.
    The Journal of biological chemistry, 2013, Mar-29, Volume: 288, Issue:13

    Topics: Amino Acid Motifs; Animals; Ascorbic Acid; Biological Transport; Cloning, Molecular; Dehydroascorbic Acid; Diet; Fructose; Glucose; Glucose Transport Proteins, Facilitative; Glucose Transporter Type 2; Humans; Intestinal Mucosa; Kinetics; Male; Mice; Mice, Knockout; Oocytes; Oxygen; Phloretin; Quercetin; Rats; Rats, Sprague-Dawley

2013
Phloretin modulates the rate of channel formation by polyenes.
    Biochimica et biophysica acta, 2016, Volume: 1858, Issue:2

    Topics: Catechin; Cholesterol; Genistein; Membranes, Artificial; Phloretin; Phosphatidylcholines; Polyenes; Quercetin

2016
Quercetin, Morin, Luteolin, and Phloretin Are Dietary Flavonoid Inhibitors of Monocarboxylate Transporter 6.
    Molecular pharmaceutics, 2017, 09-05, Volume: 14, Issue:9

    Topics: Animals; Bumetanide; Flavonoids; Humans; Luteolin; Monocarboxylic Acid Transporters; Oocytes; Phloretin; Quercetin; Xenopus laevis

2017
Sechium edule (Jacq.) Swartz, a New Cultivar with Antiproliferative Potential in a Human Cervical Cancer HeLa Cell Line.
    Nutrients, 2017, Jul-25, Volume: 9, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Apigenin; Cell Proliferation; Cucurbitaceae; Cucurbitacins; Female; Flavanones; Flavonoids; Fruit; HeLa Cells; Humans; Inhibitory Concentration 50; Phloretin; Phytochemicals; Plant Extracts; Quercetin; Rutin; Uterine Cervical Neoplasms

2017
A Holistic Evolutionary and 3D Pharmacophore Modelling Study Provides Insights into the Metabolism, Function, and Substrate Selectivity of the Human Monocarboxylate Transporter 4 (hMCT4).
    International journal of molecular sciences, 2021, Mar-13, Volume: 22, Issue:6

    Topics: Animals; Antineoplastic Agents; Binding Sites; Biological Transport; Drug Design; Glycolysis; Humans; Lactic Acid; Molecular Docking Simulation; Monocarboxylic Acid Transporters; Muscle Proteins; Phloretin; Phylogeny; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Protein Isoforms; Pyrimidinones; Quercetin; Reserpine; Structural Homology, Protein; Substrate Specificity; Thiophenes; Uracil

2021
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009