Page last updated: 2024-08-16

phloretin and genistein

phloretin has been researched along with genistein in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.76)18.2507
2000's7 (41.18)29.6817
2010's7 (41.18)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Constantinou, A; Mehta, R; Moon, R; Rao, K; Runyan, C; Vaughan, A1
Morris, ME; Nguyen, H; Zhang, S1
Morris, ME; Yang, X; Zhang, S1
Campitelli, MR; McArdle, BM; Quinn, RJ1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Amić, D; Lucić, B1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Imokawa, G; Kimura, M; Morisaki, N; Yada, Y1
Afzal, I; Cunningham, P; Naftalin, RJ1
Morris, ME; Zhang, S1
Andersen, OS; Hwang, TC; Koeppe, RE1
Andersen, OS; Koeppe, RE; Lundbaek, JA1
Hu, M; Meng, S; Morrow, JK; Singh, R; Wu, B; Yin, T; Zhang, S1
Duan, Y; Li, HF; Qiu, XQ; Tian, ZF; Wang, LD; Yang, LN; Zhang, H; Zhang, YF1
Choi, DJ; Chung, MJ; Park, YI; Sohng, JK1
Chulkov, EG; Ostroumova, OS1
Parmar, D; Sharma, A; Singh, G; Thaker, R1

Other Studies

17 other study(ies) available for phloretin and genistein

ArticleYear
Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships.
    Journal of natural products, 1995, Volume: 58, Issue:2

    Topics: DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Electrophoresis, Agar Gel; Flavonoids; Hydroxylation; Plasmids; Protein Conformation; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1995
Effect of flavonoids on MRP1-mediated transport in Panc-1 cells.
    Journal of pharmaceutical sciences, 2003, Volume: 92, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Blotting, Western; Chemokines, CC; Daunorubicin; Flavonoids; Glutathione; Glutathione Transferase; Humans; Neoplasm Proteins; Tumor Cells, Cultured; Vinblastine

2003
Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport.
    Molecular pharmacology, 2004, Volume: 65, Issue:5

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Division; Chemokines, CC; Dose-Response Relationship, Drug; Drug Interactions; Flavonoids; Humans; Mitoxantrone; Neoplasm Proteins; Tumor Cells, Cultured

2004
A common protein fold topology shared by flavonoid biosynthetic enzymes and therapeutic targets.
    Journal of natural products, 2006, Volume: 69, Issue:1

    Topics: Biological Products; Flavonoids; Models, Molecular; Molecular Structure; Piperidines; Plants, Medicinal; Protein Conformation; Protein Folding; Protein Kinase Inhibitors; Proteins

2006
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics

2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Biological characterization of human fibroblast-derived mitogenic factors for human melanocytes.
    The Biochemical journal, 1998, Mar-15, Volume: 330 ( Pt 3)

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Cellular Senescence; Culture Media, Conditioned; Culture Media, Serum-Free; Cytokines; DNA; Enzyme Inhibitors; Fibroblast Growth Factor 2; Fibroblasts; Genistein; Growth Substances; Hepatocyte Growth Factor; Humans; Interleukin-1; Kinetics; Lactams, Macrocyclic; Melanocytes; Phloretin; Protein-Tyrosine Kinases; Quinones; Rifabutin; Skin; Stem Cell Factor; Thymidine

1998
Interactions of ATP, oestradiol, genistein and the anti-oestrogens, faslodex (ICI 182780) and tamoxifen, with the human erythrocyte glucose transporter, GLUT1.
    The Biochemical journal, 2002, Aug-01, Volume: 365, Issue:Pt 3

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Biological Transport; Cytochalasin B; Enzyme Inhibitors; Erythrocyte Membrane; Estradiol; Estrogen Antagonists; Estrogen Receptor Modulators; Fulvestrant; Genistein; Glucose; Glucose Transporter Type 1; Humans; Ligands; Models, Biological; Models, Molecular; Molecular Sequence Data; Monosaccharide Transport Proteins; Phloretin; Protein Structure, Secondary; Protein Structure, Tertiary; Tamoxifen

2002
Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:3

    Topics: Adenosine Triphosphatases; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Daunorubicin; Dihydropyridines; Doxorubicin; Drug Interactions; Flavonoids; Genistein; Humans; Phloretin; Photoaffinity Labels; Silymarin; Time Factors; Transfection; Tritium; Tumor Cells, Cultured

2003
Genistein can modulate channel function by a phosphorylation-independent mechanism: importance of hydrophobic mismatch and bilayer mechanics.
    Biochemistry, 2003, Nov-25, Volume: 42, Issue:46

    Topics: Amino Acid Sequence; Dimerization; Dose-Response Relationship, Drug; Electric Conductivity; Genistein; Gramicidin; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Ion Channels; Isoflavones; Kinetics; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Phloretin; Phospholipids; Phosphorylation

2003
Amphiphile regulation of ion channel function by changes in the bilayer spring constant.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Aug-31, Volume: 107, Issue:35

    Topics: Algorithms; Capsaicin; Cell Line; Cell Membrane; Genistein; Gramicidin; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Ion Channels; Isoflavones; Kinetics; Lipid Bilayers; Membrane Potentials; Membrane Proteins; Octoxynol; Phloretin; Phosphatidylcholines; Protein Conformation

2010
SULT1A3-mediated regiospecific 7-O-sulfation of flavonoids in Caco-2 cells can be explained by the relevant molecular docking studies.
    Molecular pharmaceutics, 2012, Apr-02, Volume: 9, Issue:4

    Topics: Apigenin; Arylsulfotransferase; Binding Sites; Caco-2 Cells; Flavanones; Flavonoids; Genistein; Humans; Kaempferols; Kinetics; Phloretin; Sulfotransferases; Tandem Mass Spectrometry

2012
Effects of estrogen and phytoestrogens on endometrial leakage in ovariectomized rats and the related mechanisms.
    Sheng li xue bao : [Acta physiologica Sinica], 2013, Feb-25, Volume: 65, Issue:1

    Topics: Animals; Endothelium, Vascular; Eosinophils; Estradiol; Estrogens; Female; Genistein; NF-kappa B; Ovariectomy; Permeability; Phloretin; Phytoestrogens; Progesterone; Rats; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Uterus; Vascular Endothelial Growth Factor A

2013
Inhibitory effect of phloretin and biochanin A on IgE-mediated allergic responses in rat basophilic leukemia RBL-2H3 cells.
    Life sciences, 2013, Sep-17, Volume: 93, Issue:9-11

    Topics: Animals; Blotting, Western; Cell Line, Tumor; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Free Radical Scavengers; Genistein; Immunoglobulin E; Leukemia, Basophilic, Acute; Mitogen-Activated Protein Kinases; Phloretin; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction

2013
Phloretin modulates the rate of channel formation by polyenes.
    Biochimica et biophysica acta, 2016, Volume: 1858, Issue:2

    Topics: Catechin; Cholesterol; Genistein; Membranes, Artificial; Phloretin; Phosphatidylcholines; Polyenes; Quercetin

2016
Therapeutic effects of biochanin A, phloretin, and epigallocatechin-3-gallate in reducing oxidative stress in arsenic-intoxicated mice.
    Environmental science and pollution research international, 2021, Volume: 28, Issue:16

    Topics: Animals; Antioxidants; Arsenic; Catechin; Genistein; Humans; Lipid Peroxidation; Liver; Male; Mice; Oxidative Stress; Phloretin; Protein Carbonylation; Sperm Motility

2021