phenytoin and zonisamide

phenytoin has been researched along with zonisamide in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (6.25)	18.7374
1990's	12 (18.75)	18.2507
2000's	22 (34.38)	29.6817
2010's	20 (31.25)	24.3611
2020's	6 (9.38)	2.80

Authors

Authors	Studies
Kurokawa, M; Masuda, Y; Nishimura, H; Uno, H	1
Dodgson, SP; Gardocki, JF; Maryanoff, BE; Nortey, SO; Shank, RP	1
Anger, T; Madge, DJ; Mulla, M; Riddall, D	1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R	1
Huber, VJ; Kwee, IL; Nakada, T; Tsujita, M	1
Verkman, AS; Yang, B; Zhang, H	1
Duncton, MA; Emerling, DE; Kelly, MG; Nguyen, MT; Vincent, F	1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC	1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP	1
Kiyoshi, T; Miura, Y; Tanaka, T; Tanitame, A; Yajima, N	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Fukuchi, H; Kimura, M; Kimura, Y; Kitaura, T; Miyake, K; Tanaka, N	2
Fujita, T; Takano, K; Tanaka, S; Tanaka, T; Yonemasu, Y	1
Fujikawa, Y; Fujiwara, T; Kubota, H; Matsuda, K; Seino, M; Yagi, K	1
Hasegawa, H; Okuda, H; Wada, Y; Yamaguchi, N	1
Buchanan, RA; Friel, PN; Levy, RH; McLean, JR; Ojemann, LM; Shastri, RA; Wilensky, AJ	1
Kakegawa, N; Seino, M	1
Miura, H	1
Asai, N; Hamanaka, T; Hiyoshi, T; Hori, S; Ishikawa, T; Mochizuki, H; Tsuji, M	1
Akaho, R	1
Akita, M; Hasegawa, M; Hasegawa, T; Nabeshima, T; Shinoda, M	1
Futagami, K; Goto, Y; Kataoka, Y; Makino, K; Oishi, R; Sueyasu, M	1
Hagan, RM; Higgins, GA; Kirkby, D; Southam, E	1
Hattori, H; Ikeda, A; Kimura, J; Odani, A; Shibasaki, H	1
Kanemoto, K; Kawasaki, J; Miyamoto, T	1
Akasaki, Y; Hashiguchi, W; Nagatomo, I; Takigawa, M; Tominaga, M; Uchida, M	1
Backonja, MM	1
Bergin, AM; Connolly, M	1
Araki, H; Futagami, K; Gomita, Y; Hashimoto, Y; Kawasaki, H	1
Fukuoka, N; Kimura, M; Morita, S; Tsukamoto, T; Uno, J	2
Fujiwara, T; Iinuma, K	1
Yatham, LN	1
Garnett, WR; Levy, RH; Pan, WJ; Ragueneau-Majlessi, I; Rosenfeld, W; Schmerler, M; Shah, J	1
Kamei, J; Mayanagi, H; Onodera, K; Saito, T; Takahashi, A	1
Kuribayashi, Y; Onodera, K; Takahashi, A	1
Goto, S; Ishitsu, T; Murata, T; Nakada, N; Nakagawa, K; Seo, T; Ueda, N	1
Edelbroek, PM; Vermeij, TA	1
Takahashi, Y	1
Lee, EL; Tor, PC	1
Hamaguchi, T; Kanehara, S; Matsumoto, T; Motomura, E; Nakagawa, M; Ohoyama, K; Okada, M; Shiroyama, T; Sugiura, Y; Suzuki, D; Tanii, H; Yamamura, S	1
Fukatsu, N; Kanemoto, K; Kato, H; Noguchi, T; Oshima, T	1
Imai, K; Inoue, K; Inoue, Y; Itoh, K; Kagawa, Y; Mishima, N; Takahashi, Y; Yamamoto, Y; Yazawa, R	1
Greenhalgh, J; Marson, AG; Pulman, J	1
Alvarez-Pérez, P; Lema-Facal, T; López-Facal, S; Rubio-Nazabal, E	1
Greenhalgh, J; Marson, AG; Weston, J	1
Horvath, R; Janszky, J; Komoly, S	1
Brandão, MAF; Ferreira, AO; Patrício, FB; Polonini, HC; Raposo, NRB; Silva, SL	1
Abe, S; Azuma, Y; Ishihara, N; Ito, Y; Itomi, K; Kidokoro, H; Kojima, S; Kurahashi, H; Kurahashi, N; Maruyama, K; Natsume, J; Negoro, T; Okumura, A; Suzuki, M; Takeuchi, T; Tsuji, T; Watanabe, K; Yamada, K; Yamamoto, H	1
Chervoneva, I; Miller, R; Mintzer, S; Nei, M; Shah, K; Skidmore, C; Sperling, MR	1
Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS	1
Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J	2
Conejo-Moreno, D; Gutierrez-Alvarez, AM; Jimenez-Corral, C; Ortiz-Madinaveitia, S; Sagarra-Mur, D; Serrano-Madrid, ML	1
Dundar, Y; Greenhalgh, J; Marson, AG; Nevitt, SJ; Weston, J	2
Ahmed, SI; Laghari, AA; Qadeer, N; Shamim, MS	1
Chu, YJ; Fan, PC; Liao, CH; Liao, YF	1
Ajinkya, S; Fox, J; Lekoubou, A	1
Govindan, R; Sharma, S; Trivedi, A	1
Ahn, KM; Chung, SJ; Oh, JH; Park, HW; Shim, JS	1
Adamovich-Zeitlin, RH; Camp, EJ; Gross, RE; Jobst, BC; Kahana, MJ; Lega, BC; MacKenzie, TA; Meisenhelter, S; Quon, RJ; Song, Y; Sperling, MR; Steimel, SA; Testorf, ME	1
Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T	1

Reviews

17 review(s) available for phenytoin and zonisamide

Article	Year
Medicinal chemistry of neuronal voltage-gated sodium channel blockers. Journal of medicinal chemistry, 2001, Jan-18, Volume: 44, Issue:2 Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Sodium Channel Blockers; Sodium Channels; Stroke	2001
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Use of anticonvulsants for treatment of neuropathic pain. Neurology, 2002, Sep-10, Volume: 59, Issue:5 Suppl 2 Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nervous System Diseases; Pain; Phenytoin; Triazines; Zonisamide	2002
New antiepileptic drug therapies. Neurologic clinics, 2002, Volume: 20, Issue:4 Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Phenytoin; Piracetam; Propylene Glycols; Thiazines; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide	2002
[Clinical guidelines for treatment of epilepsy in children]. No to hattatsu = Brain and development, 2004, Volume: 36, Issue:2 Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Cosyntropin; Electroencephalography; Epilepsy; Frontal Lobe; Humans; Isoxazoles; Life Style; Magnetic Resonance Imaging; Phenytoin; Practice Guidelines as Topic; Temporal Lobe; Valproic Acid; Zonisamide	2004
Newer anticonvulsants in the treatment of bipolar disorder. The Journal of clinical psychiatry, 2004, Volume: 65 Suppl 10 Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Depressive Disorder; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide	2004
[Neuromuscular disorders caused by adverse effects of antiepileptics]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007, Aug-10, Volume: 96, Issue:8 Topics: Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Neuromuscular Diseases; Phenobarbital; Phenytoin; Topiramate; Valproic Acid; Zonisamide	2007
Antiepileptic drugs as prophylaxis for post-craniotomy seizures. The Cochrane database of systematic reviews, 2013, Feb-28, Issue:2 Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide	2013
Antiepileptic drugs as prophylaxis for post-craniotomy seizures. The Cochrane database of systematic reviews, 2015, Mar-04, Issue:3 Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide	2015
[ZONISAMIDE: FIRST CHOICE AMONG THE FIRST-LINE ANTIEPILEPTIC DRUGS IN FOCAL EPILEPSY]. Ideggyogyaszati szemle, 2015, May-30, Volume: 68, Issue:5-6 Topics: Adolescent; Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Drug Administration Schedule; Drug Approval; Drug Prescriptions; Electroencephalography; Encephalitis; Epilepsies, Partial; Humans; Hungary; Isoxazoles; Levetiracetam; Magnetic Resonance Imaging; Medication Adherence; Obesity; Phenytoin; Piracetam; Risk Assessment; Risk Factors; Seizures; Stroke; Weight Loss; Young Adult; Zonisamide	2015
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy. Journal of critical care, 2016, Volume: 36 Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide	2016
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data. The Cochrane database of systematic reviews, 2017, 06-29, Volume: 6 Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide	2017
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data. The Cochrane database of systematic reviews, 2017, 12-15, Volume: 12 Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide	2017
Antiepileptic drugs as prophylaxis for postcraniotomy seizures. The Cochrane database of systematic reviews, 2018, 05-23, Volume: 5 Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Levetiracetam; Phenobarbital; Phenytoin; Piracetam; Postoperative Complications; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide	2018
Choice of therapeutic anti-seizure medication in patients with brain tumour. JPMA. The Journal of the Pakistan Medical Association, 2019, Volume: 69, Issue:3 Topics: Anticonvulsants; Brain Neoplasms; Drug Therapy, Combination; Epilepsy; Gabapentin; Glioma; Humans; Lamotrigine; Levetiracetam; Neoplasm Grading; Phenytoin; Survival Rate; Topiramate; Valproic Acid; Zonisamide	2019
Antiepileptic drugs as prophylaxis for postcraniotomy seizures. The Cochrane database of systematic reviews, 2020, 04-28, Volume: 4 Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Levetiracetam; Phenobarbital; Phenytoin; Piracetam; Postoperative Complications; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide	2020
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force Epileptic disorders : international epilepsy journal with videotape, 2022, 12-01, Volume: 24, Issue:6 Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide	2022

Trials

3 trial(s) available for phenytoin and zonisamide

Article	Year
Developmental and therapeutic pharmacology of antiepileptic drugs. The Japanese journal of psychiatry and neurology, 1993, Volume: 47, Issue:2 Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electroencephalography; Epilepsy; Female; Half-Life; Humans; Infant; Isoxazoles; Male; Phenytoin; Prospective Studies; Valproic Acid; Zonisamide	1993
The effects of antiepileptic drugs on cognition in normal volunteers. Psychiatry and clinical neurosciences, 1996, Volume: 50, Issue:2 Topics: Adult; Anticonvulsants; Carbamazepine; Cognition; Cross-Over Studies; Double-Blind Method; Humans; Isoxazoles; Phenytoin; Valproic Acid; Wechsler Scales; Zonisamide	1996
Lack of a clinically significant effect of zonisamide on phenytoin steady-state pharmacokinetics in patients with epilepsy. Journal of clinical pharmacology, 2004, Volume: 44, Issue:11 Topics: Adolescent; Adult; Anticonvulsants; Area Under Curve; Drug Interactions; Epilepsy; Female; Humans; Isoxazoles; Male; Metabolic Clearance Rate; Middle Aged; Phenytoin; Zonisamide	2004

Other Studies

44 other study(ies) available for phenytoin and zonisamide

Article	Year
Studies on 3-substituted 1,2-benzisoxazole derivatives. 6. Syntheses of 3-(sulfamoylmethyl)-1,2-benzisoxazole derivatives and their anticonvulsant activities. Journal of medicinal chemistry, 1979, Volume: 22, Issue:2 Topics: Animals; Anticonvulsants; Benzoxazoles; Electroshock; Male; Mice; Nervous System Diseases; Postural Balance; Structure-Activity Relationship	1979
Anticonvulsant O-alkyl sulfamates. 2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate and related compounds. Journal of medicinal chemistry, 1987, Volume: 30, Issue:5 Topics: Animals; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Electroshock; Fructose; Kinetics; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Phenytoin; Seizures; Structure-Activity Relationship; Topiramate	1987
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship	2003
Inhibition of aquaporin 4 by antiepileptic drugs. Bioorganic & medicinal chemistry, 2009, Jan-01, Volume: 17, Issue:1 Topics: Animals; Anticonvulsants; Aquaporin 4; Computer Simulation; Drug Evaluation, Preclinical; Humans; Oocytes; Protein Binding; Thermodynamics; Xenopus	2009
Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides. Bioorganic & medicinal chemistry, 2008, Aug-01, Volume: 16, Issue:15 Topics: Animals; Anticonvulsants; Aquaporin 4; Biological Transport, Active; Cell Line; Mice; Molecular Structure; Neuroglia; Permeability; Rats; Structure-Activity Relationship; Sulfonamides; Thyroid Gland; Water	2008
Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors. Bioorganic & medicinal chemistry letters, 2009, Dec-01, Volume: 19, Issue:23 Topics: Amidohydrolases; Carbamates; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Piperazines; Stereoisomerism; Structure-Activity Relationship	2009
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility	2010
Species independence in brain tissue binding using brain homogenates. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity	2011
Discovery of benzothiazine derivatives as novel, orally-active anti-epileptic drug candidates with broad anticonvulsant effect. Bioorganic & medicinal chemistry letters, 2015, Oct-15, Volume: 25, Issue:20 Topics: Administration, Oral; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Electroshock; Epilepsy; Injections, Subcutaneous; Kindling, Neurologic; Mice; Molecular Structure; Pentylenetetrazole; Rats; Seizures; Structure-Activity Relationship; Thiazines	2015
Pharmacokinetic interaction of zonisamide in rats. Effect of other antiepileptics on zonisamide. Journal of pharmacobio-dynamics, 1992, Volume: 15, Issue:11 Topics: Administration, Oral; Animals; Anticonvulsants; Blood Proteins; Diethylcarbamazine; Drug Interactions; Erythrocytes; Half-Life; Isoxazoles; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Valproic Acid; Zonisamide	1992
[Effect of anticonvulsants upon experimental limbic seizure status and regional cerebral blood flow in the hippocampus]. No to shinkei = Brain and nerve, 1992, Volume: 44, Issue:3 Topics: Animals; Anticonvulsants; Cats; Diazepam; Electroencephalography; Hippocampus; Isoxazoles; Phenobarbital; Phenytoin; Regional Blood Flow; Status Epilepticus; Valproic Acid; Zonisamide	1992
Reversal of MRI lesion with relapse and remission of partial motor seizures in epilepsia partialis continua. The Japanese journal of psychiatry and neurology, 1991, Volume: 45, Issue:2 Topics: Adolescent; Anticonvulsants; Cerebral Cortex; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Follow-Up Studies; Humans; Isoxazoles; Magnetic Resonance Imaging; Male; Phenytoin; Zonisamide	1991
Anticonvulsant effects of zonisamide and phenytoin on seizure activity of the feline visual cortex. Brain & development, 1990, Volume: 12, Issue:2 Topics: Animals; Anticonvulsants; Cats; Dose-Response Relationship, Drug; Epilepsy; Female; Isoxazoles; Kindling, Neurologic; Male; Oxazoles; Phenytoin; Visual Cortex; Zonisamide	1990
Comparative pharmacokinetics of zonisamide (CI-912) in epileptic patients on carbamazepine or phenytoin monotherapy. Therapeutic drug monitoring, 1986, Volume: 8, Issue:3 Topics: Adolescent; Adult; Anticonvulsants; Body Weight; Carbamazepine; Drug Therapy, Combination; Epilepsy; Erythrocytes; Female; Humans; Isoxazoles; Kinetics; Male; Oxazoles; Phenytoin; Zonisamide	1986
Therapeutic concentration of antiepileptic drugs and the severity of epileptogenesis. Electroencephalography and clinical neurophysiology. Supplement, 1982, Volume: 36 Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Isoxazoles; Phenytoin; Valproic Acid; Zonisamide	1982
Two epileptics showing antiepileptic drug-induced psychoses. The Japanese journal of psychiatry and neurology, 1993, Volume: 47, Issue:2 Topics: Adolescent; Anticonvulsants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Humans; Isoxazoles; Male; Phenytoin; Psychoses, Substance-Induced; Zonisamide	1993
Pharmacokinetic interaction of zonisamide in rats. Effect of zonisamide on other antiepileptics. Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:7 Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Drug Interactions; Erythrocytes; In Vitro Techniques; Isoxazoles; Male; Phenobarbital; Phenytoin; Protein Binding; Rats; Rats, Wistar; Valproic Acid; Zonisamide	1993
The necessity of adjusting the dosage of zonisamide when coadministered with other anti-epileptic drugs. Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:8 Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Valproic Acid; Zonisamide	1996
Micellar electrokinetic capillary chromatography for therapeutic drug monitoring of zonisamide. Journal of chromatography. B, Biomedical sciences and applications, 1997, Aug-01, Volume: 695, Issue:2 Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Electrophoresis, Capillary; Fluorescence Polarization Immunoassay; Humans; Isoxazoles; Phenobarbital; Phenytoin; Zonisamide	1997
Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats. European journal of pharmacology, 1998, Sep-25, Volume: 358, Issue:1 Topics: Acetates; Amines; Animals; Anticonvulsants; Biogenic Amines; Blood Platelets; Brain; Carbamazepine; Cyclohexanecarboxylic Acids; Dopamine; Dopamine Uptake Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium; Male; Norepinephrine; p-Chloroamphetamine; Phenytoin; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Syndrome; Synaptosomes; Tetrodotoxin; Triazines; Valproic Acid; Zonisamide	1998
Gynaecomastia in association with phenytoin and zonisamide in a patient having a CYP2C subfamily mutation. Journal of neurology, neurosurgery, and psychiatry, 1998, Volume: 65, Issue:5 Topics: Adult; Anticonvulsants; Epilepsies, Partial; Gynecomastia; Humans; Isoxazoles; Male; Metabolism, Inborn Errors; Phenytoin; Point Mutation; Zonisamide	1998
Running down phenomenon and acute interictal psychosis in medial temporal lobe epilepsy. Epilepsy research, 2000, Volume: 39, Issue:1 Topics: Adult; Age Factors; Anticonvulsants; Epilepsy, Temporal Lobe; Female; Humans; Isoxazoles; Male; Phenytoin; Psychoses, Substance-Induced; Recurrence; Sclerosis; Temporal Lobe; Zonisamide	2000
Effects of combined administration of zonisamide and valproic acid or phenytoin to nitric oxide production, monoamines and zonisamide concentrations in the brain of seizure-susceptible EL mice. Brain research bulletin, 2000, Sep-15, Volume: 53, Issue:2 Topics: Animals; Anticonvulsants; Biogenic Monoamines; Brain; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Epilepsy; Isoxazoles; Mice; Mice, Mutant Strains; Nitric Oxide; Phenytoin; Valproic Acid; Zonisamide	2000
Effects of valproate, phenytoin, and zonisamide on clonic and tonic seizures induced by acute and repeated exposure of mice to flurothyl. Physiology & behavior, 2003, Volume: 78, Issue:3 Topics: Animals; Anticonvulsants; Brain Stem; Convulsants; Epilepsy, Tonic-Clonic; Flurothyl; Isoxazoles; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Phenytoin; Prosencephalon; Seizures; Time Factors; Valproic Acid; Zonisamide	2003
Influence of coadministered antiepileptic drugs on serum zonisamide concentrations in epileptic patients: quantitative analysis based on suitable transforming factor. Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:12 Topics: Administration, Oral; Adolescent; Adult; Aging; Anticonvulsants; Biological Availability; Body Surface Area; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Isoxazoles; Male; Patient Selection; Phenytoin; Powders; Regression Analysis; Sex; Tablets; Zonisamide	2003
Influence of coadministered antiepileptic drugs on serum phenobarbital concentrations in epileptic patients: quantitative analysis based on a suitable transforming factor. Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:12 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Combinations; Epilepsy; Female; Humans; Infant; Isoxazoles; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Valproic Acid; Zonisamide	2004
Effects of the antiepileptics phenytoin and zonisamide on dentin formation and bone mineral density of the mandible in growing rats. Methods and findings in experimental and clinical pharmacology, 2004, Volume: 26, Issue:10 Topics: Animals; Bone Density; Calcium; Dentin; Drug Administration Schedule; Durapatite; Gingival Hyperplasia; Incisor; Injections, Subcutaneous; Isoxazoles; Male; Mandible; Microradiography; Phenytoin; Rats; Rats, Wistar; Zonisamide	2004
[An animal model of antiepileptic-induced osteoporosis in rats]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2006, Volume: 127, Issue:5 Topics: Animals; Anticonvulsants; Bone Density; Disease Models, Animal; Isoxazoles; Osteoporosis; Phenytoin; Rats; Zonisamide	2006
Population estimation of the effects of cytochrome P450 2C9 and 2C19 polymorphisms on phenobarbital clearance in Japanese. Therapeutic drug monitoring, 2007, Volume: 29, Issue:1 Topics: Adult; Algorithms; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Asian People; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Monitoring; Epilepsy; Female; Gene Frequency; Genetics, Population; Heterozygote; Homozygote; Humans; Immunoassay; Isoxazoles; Japan; Male; Metabolic Clearance Rate; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Polymorphism, Genetic; Regression Analysis; Valproic Acid; Zonisamide	2007
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Sep-15, Volume: 857, Issue:1 Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Drug Monitoring; Ethosuximide; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature; Triazines; Valproic Acid; Zonisamide	2007
Treatment emergent mania responding to valproate in a Chinese female adolescent population with eating disorders: a case series. European eating disorders review : the journal of the Eating Disorders Association, 2008, Volume: 16, Issue:6 Topics: Adolescent; Anorexia Nervosa; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Bulimia Nervosa; Feeding and Eating Disorders; Female; Humans; Isoxazoles; Male; Phenytoin; Risk Factors; Sex Characteristics; Singapore; Valproic Acid; Young Adult; Zonisamide	2008
Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin. Epilepsy research, 2009, Volume: 84, Issue:2-3 Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Extracellular Fluid; Fructose; Hippocampus; Isoxazoles; Male; Movement; Neurotransmitter Agents; Phenytoin; Rats; Rats, Sprague-Dawley; Topiramate; Zonisamide	2009
Impact of antiepileptic drugs on genesis of psychosis. Epilepsy & behavior : E&B, 2012, Volume: 23, Issue:4 Topics: Adolescent; Adult; Anticonvulsants; Epilepsy, Complex Partial; Female; Follow-Up Studies; Humans; International Classification of Diseases; Isoxazoles; Male; Middle Aged; Phenytoin; Psychotic Disorders; Retrospective Studies; Young Adult; Zonisamide	2012
Risk factors for hyperammonemia in pediatric patients with epilepsy. Epilepsia, 2013, Volume: 54, Issue:6 Topics: Acetazolamide; Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy; Female; Fructose; Humans; Hyperammonemia; Infant; Isoxazoles; Male; Phenobarbital; Phenytoin; Retrospective Studies; Risk Factors; Sex Factors; Topiramate; Valproic Acid; Zonisamide	2013
[Othello syndrome secondary to zonisamide]. Medicina clinica, 2014, Feb-04, Volume: 142, Issue:3 Topics: Adult; Anticonvulsants; Brain Diseases; Cysts; Delusions; Drug Substitution; Drug Therapy, Combination; Epilepsies, Partial; Humans; Isoxazoles; Jealousy; Male; Phenytoin; Syndrome; Zonisamide	2014
Feasibility of amlodipine besylate, chloroquine phosphate, dapsone, phenytoin, pyridoxine hydrochloride, sulfadiazine, sulfasalazine, tetracycline hydrochloride, trimethoprim and zonisamide in SyrSpend(®) SF PH4 oral suspensions. Journal of pharmaceutical and biomedical analysis, 2016, Jan-25, Volume: 118 Topics: Administration, Oral; Amlodipine; Chloroquine; Chromatography, High Pressure Liquid; Dapsone; Drug Stability; Drug Storage; Feasibility Studies; Hydrogen-Ion Concentration; Isoxazoles; Phenytoin; Pyridoxine; Sulfadiazine; Sulfasalazine; Suspensions; Tetracycline; Trimethoprim; Zonisamide	2016
The effects of co-medications on lamotrigine clearance in Japanese children with epilepsy. Brain & development, 2016, Volume: 38, Issue:8 Topics: Adolescent; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Infant, Newborn; Isoxazoles; Japan; Lamotrigine; Levetiracetam; Male; Phenobarbital; Phenytoin; Piracetam; Triazines; Valproic Acid; Young Adult; Zonisamide	2016
Long-term effect of antiepileptic drug switch on serum lipids and C-reactive protein. Epilepsy & behavior : E&B, 2016, Volume: 58 Topics: Anticonvulsants; Biomarkers; C-Reactive Protein; Carbamazepine; Drug Substitution; Drug Therapy, Combination; Epilepsies, Partial; Female; Fructose; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Lipids; Male; Middle Aged; Phenytoin; Piracetam; Time Factors; Topiramate; Treatment Outcome; Triazines; Zonisamide	2016
[Early onset epileptic encephalopathy in a patient with mutation in Revista de neurologia, 2017, Dec-16, Volume: 65, Issue:12 Topics: Age of Onset; Amino Acid Substitution; Anticonvulsants; Child, Preschool; Drug Resistant Epilepsy; Drug Substitution; Electroencephalography; Heterozygote; Humans; Intellectual Disability; Isoxazoles; Male; Mutation, Missense; NAV1.6 Voltage-Gated Sodium Channel; Phenytoin; Point Mutation; Zonisamide	2017
Pharmacotherapy and electroencephalographic evolution in SCN8A encephalopathy: A case report. Journal of the Formosan Medical Association = Taiwan yi zhi, 2019, Volume: 118, Issue:8 Topics: Anticonvulsants; Brain Diseases; Diagnosis, Differential; Electroencephalography; Epilepsy; Humans; Infant, Newborn; Male; Mutation; NAV1.6 Voltage-Gated Sodium Channel; Phenytoin; Treatment Outcome; Zonisamide	2019
Patterns of antiepileptic drug use among elderly patients with epilepsy: 2004-2015. Epilepsy research, 2020, Volume: 161 Topics: Aged; Aged, 80 and over; Aging; Anticonvulsants; Carbamazepine; Cross-Sectional Studies; Epilepsy; Female; Humans; Levetiracetam; Male; Middle Aged; Phenytoin; Seizures; Zonisamide	2020
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a paediatric patient taking zonisamide. European journal of hospital pharmacy : science and practice, 2022, Volume: 29, Issue:4 Topics: Child; Drug Hypersensitivity Syndrome; Eosinophilia; Exanthema; Humans; Male; Phenytoin; Zonisamide	2022
Incidence rates of severe cutaneous adverse reactions due to antiseizure medication: A nationwide study using health claims data in Korea. Epilepsia, 2021, Volume: 62, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Drug Hypersensitivity Syndrome; Female; Humans; Incidence; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenytoin; Republic of Korea; Severity of Illness Index; Stevens-Johnson Syndrome; Topiramate; Young Adult; Zonisamide	2021
Factors correlated with intracranial interictal epileptiform discharges in refractory epilepsy. Epilepsia, 2021, Volume: 62, Issue:2 Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Drug Resistant Epilepsy; Electrocorticography; Female; Humans; Lacosamide; Lamotrigine; Levetiracetam; Male; Mental Recall; Middle Aged; Phenytoin; Time Factors; Topiramate; Zonisamide	2021