phenytoin has been researched along with valproic acid in 1038 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 365 (35.16) | 18.7374 |
| 1990's | 272 (26.20) | 18.2507 |
| 2000's | 174 (16.76) | 29.6817 |
| 2010's | 172 (16.57) | 24.3611 |
| 2020's | 55 (5.30) | 2.80 |
| Authors | Studies |
|---|---|
| Brahce, L; Gregor, VE; Lobbestael, SJ; Mayhugh, DR; Nugiel, D; Pavia, MR; Schwarz, RD; Taylor, CP; Vartanian, MG | 1 |
| Chang, H; Edafiogho, IO; Hinko, CN; Moore, JA; Mulzac, D; Nicholson, JM; Scott, KR | 1 |
| Johnson, DN; Kilpatrick, BF; Kinnier, WB; Lo, YS; Moses, LM; Sutherland, DB; Taylor, CR; Tomczuk, BE | 1 |
| Kohn, H; Leander, JD; LeGall, P; Robertson, DW; Sawhney, KN | 1 |
| Edafiogho, IO; Farrar, VA; Moore, JA; Nicholson, JM; Scott, KR | 1 |
| Baron, BM; Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM; Staeger, MA | 1 |
| Conley, JD; Kohn, H; Leander, JD; LeGall, P; Robertson, DW; Sawhney, KN | 1 |
| Goehring, RR; Greenwood, TD; Nwokogu, GC; Pisipati, JS; Rogers, TG; Wolfe, JF | 1 |
| Baker, JK; Wall, GM | 1 |
| Chimirri, A; De Sarro, A; De Sarro, G; Grasso, S; Trimarchi, GR; Zappalà, M | 1 |
| Kadaba, PK | 1 |
| Clark, CR; Lin, CM; Sansom, RT | 1 |
| Conley, JD; Kohn, H | 1 |
| Clark, CR; Lin, CM; Norris, GN; Sansom, RT | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Diuguid, CA; Mehta, NB; Soroko, FE | 1 |
| Bardel, P; Bolanos, A; Kohn, H | 1 |
| Bardel, P; Kohn, H; Leander, JD; Robertson, DW; Sawhney, KN | 1 |
| Ciechanowicz-Rutkowska, M; Edafiogho, IO; el-Assadi, A; Farrar, VA; Filippini, G; Grochowski, J; Hinko, CN; Moore, JA; Pilati, T; Serda, P | 1 |
| Dalton, CR; Dudley, MW; Kane, JM; Kehne, JH; Ketteler, HJ; McCloskey, TC; Miller, FP; Ogden, AM; Senyah, Y; Staeger, MA | 1 |
| Choi, D; Kohn, H; Stables, JP | 1 |
| Flaherty, PT; Greenwood, TD; Manheim, AL; Wolfe, JF | 1 |
| Dimmock, JR; Hetherington, M; Lechler, T; Pugazhenthi, U; Puthucode, RN; Quail, JW; Smith, JM; Stables, JP | 1 |
| Almond, HR; Carmosin, RJ; Carson, JR; Pitis, PM; Stables, JP; Swinyard, EA; Vaught, JL; White, HS; Wolf, HH | 1 |
| Geurts, M; Lambert, DM; Poupaert, JH; Scriba, GK | 1 |
| Bonsignori, A; Colombo, M; Dostert, P; Fariello, RG; Heidempergher, F; McArthur, RA; Pevarello, P; Pinciroli, V; Post, C; Salvati, P; Varasi, M | 1 |
| Cacciaguerra, S; Delarge, J; Depovere, P; Isa, M; Masereel, B; Poupaert, JH; Spampinato, S; Stables, JP; Ucar, H; Van derpoorten, K | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Andurkar, SV; Béguin, C; Kohn, H; Stables, JP | 1 |
| Kohn, H; LeTiran, A; Stables, JP | 1 |
| Bräuner-Osborne, H; Bruno, G; Conti, P; De Amici, M; De Micheli, C; De Sarro, G; Joppolo Di Ventimiglia, S; Madsen, U; Russo, E; Stensbøl, TB | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Chai, KY; Kwak, KC; Piao, HR; Quan, ZS; Xie, ZF | 1 |
| Pavana, RK; Raghavendran, JV; Sriram, D; Stables, J; Sudhan, K; Thirumurugan, R; Yogeeswari, P | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Alam, M; Arshad, MF; Bhat, MA; Khan, SA; Pandeya, SN; Rana, A; Siddiqui, N; Stables, J | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Huber, VJ; Kwee, IL; Nakada, T; Tsujita, M | 1 |
| Alkskas, IA; Azam, F; Khokra, SL; Prakash, O | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Park, JY; Park, MS; Sharma, G | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Brenneman, D; Cuyckens, F; Finley, MF; Herb, M; Huang, Y; Iannucci, R; Klein, B; Leclercq, L; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Alkskas, IA; Azam, F; El-Gnidi, BA | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Kohn, H; Morieux, P; Park, KD; Salomé, C; Stables, JP | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| De Ryck, M; Dinsmore, J; Kaminski, R; King, AM; Kohn, H; Salomé, C; Salomé-Grosjean, E; Valade, A | 1 |
| Marona, H; Pękala, E; Szneler, E; Walczak, M; Waszkielewicz, AM | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| He, X; Hu, X; Wu, W; Wu, Z; Xiao, Y; Zhang, T; Zhong, M | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Dustrude, ET; Khanna, R; Kohn, H; Lee, H; Park, KD; Wilson, SM; Yang, XF | 1 |
| Chlebek, I; Kamiński, K; Obniska, J; Rzepka, S; Wiklik, B | 1 |
| Brenneman, DE; Finley, MF; Herb, M; Klein, BD; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS; Wilcox, KS | 1 |
| Kumari, S; Mishra, CB; Tiwari, M | 1 |
| Cummins, TR; Dustrude, ET; Khanna, R; Kohn, H; Torregrosa, R; Yang, XF | 1 |
| Filipek, B; Kamiński, K; Obniska, J; Pękala, E; Powroźnik, B; Rapacz, A; Rybka, S; Żmudzki, P | 1 |
| Edayadulla, N; Ramesh, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Góra, M; Kamiński, K; Obniska, J; Rapacz, A; Rybka, S; Sałat, K; Żmudzki, P | 1 |
| Budziszewska, B; Koczurkiewicz, P; Marona, H; Pańczyk, K; Pękala, E; Piska, K; Pytka, K; Rapacz, A; Starek-Świechowicz, B; Waszkielewicz, AM | 1 |
| Jamal Gilani, S; Kala, C; Prakash Dixit, S; Sarim Imam, S; Zaheen Hassan, M | 1 |
| Akhtar, MJ; Bhatia, R; Grover, G; Nath, R | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Bohlen, N; Hertl, M | 1 |
| Roger, J; Tassinari, CA | 1 |
| Richens, A | 2 |
| Lascelles, PT; Patsalos, PN | 5 |
| Buchthal, A | 1 |
| Egli, M | 1 |
| Dreifuss, FE | 2 |
| Flachs, H; Gram, L; Parnas, J | 2 |
| Bardy, A; Hari, R; Lehtovaara, R; Majuri, H | 2 |
| Fichsel, H; Knöpfle, G | 1 |
| Penin, H | 1 |
| Bruni, J; Wilder, BJ | 2 |
| Boenigk, HE; May, T; Rambeck, B | 1 |
| Bruni, J; Gallo, JM; Wilder, BJ | 1 |
| Cramer, JA; Mattson, RH | 1 |
| Hanna, GR; Johnson, RN; Nowack, WJ | 2 |
| Friel, PN; Leal, KW; Wilensky, AJ | 1 |
| Livingston, S; Pauli, LL; Pruce, I | 1 |
| Poser, S; Poser, W; Ritter, G | 1 |
| Sauer, W; Windorfer, A | 1 |
| Brett, E | 1 |
| Stünkel, S; Weinmann, HM; Windorfer, A | 1 |
| Trompetter-van Woerden, ML; van der Zwan, A | 1 |
| Flachs, H; Gram, L; Lohren, V; Rasmussen, KE; Sommerbeck, KW; Wulff, K; Würtz-Jorgensen, A | 1 |
| Johannessen, SI | 1 |
| Araki, Y; Ueki, S; Watanabe, S | 1 |
| Aucamp, AK; Joubert, PH; Potgieter, GM; Verster, F | 1 |
| Jeavons, PM | 1 |
| Klotz, U | 1 |
| Calzetti, S; Caravaggi, M; De Bernardi, M; Frigo, GM; Gatti, G; Lecchini, S; Visintini, D | 1 |
| Hori, M; Ito, T; Shimizu, M; Yoshida, K | 3 |
| Helenius, T; Liewendahl, K; Majuri, H | 1 |
| Cramer, JA; Mattson, RH; Novelly, RA; Williamson, PD | 1 |
| Fröscher, W; Gugler, R; Schulz, HU | 1 |
| Mimaya, H | 1 |
| Conomy, JP | 1 |
| Gourmel, B; Nataf, N; Rossignol, P | 1 |
| Boobis, S; Monks, A; Richens, A; Wadsworth, J | 1 |
| Göbel, W; Löscher, W | 1 |
| Levy, RH; Patel, IH | 1 |
| Bruni, J | 2 |
| Newmark, ME; Penry, JK | 1 |
| Johnson, RH; Lambie, DG; Nanda, RN; Shakir, RA | 1 |
| Addy, DP | 1 |
| Andersen, B; Flachs, H; Gram, L; Parnas, J; Würtz-Jørgensen, A | 1 |
| Barbour, B; Bruni, J; Wilder, BJ; Willmore, LJ | 1 |
| Reith, H; Schäfer, H | 1 |
| Calzetti, S; Cattaino, G; Frigo, GM; Gatti, G; Lecchini, S; Lombardi, M; Visintini, D | 1 |
| Rylance, G | 1 |
| Curless, RG | 1 |
| Crawford, RD; Davis, HL; Johnson, DD | 1 |
| Deisenhammer, E; Sommer, R | 1 |
| Borgå, O; Dahlqvist, R; Rane, A; Sjöqvist, F; Walsh, Z | 1 |
| Crema, A; Frigo, GM; Gatti, G; Lecchini, S; Perucca, E | 1 |
| Fierz, L; Karbowski, K; Robert, F | 1 |
| Wada, JA | 1 |
| Brachet, A; Henry, P; Loiseau, P | 1 |
| Boucharlat, PJ; Ledru, J; Maitre, A; Ratel, M | 1 |
| Gastaut, H; Osuntokun, BO | 1 |
| Dam, M; Hvidberg, EF | 1 |
| Hassan, MN; Laljee, HC; Parsonage, MJ | 1 |
| Bigler, ED; Fleming, DE; Shearer, DE | 1 |
| Coulthard, MG | 1 |
| Gädeke, R; Sauer, W; Windorfer, A | 1 |
| Ahmad, S; Richens, A | 1 |
| Fukuchi, H; Kimura, M; Kimura, Y; Kitaura, T; Miyake, K; Tanaka, N | 2 |
| Manford, M | 1 |
| Watanabe, M; Yagi, K | 1 |
| Koryntová, H; Mares, P; Pohl, M | 1 |
| Bigarella, MM; Bittencourt, PR; Dóro, MP; Ferreira, ZS; Gorz, AM; Mader, MJ; Marcourakis, TM | 1 |
| Akaike, N; Kameda, H; Kataoka, M; Takahashi, K; Ueno, S | 1 |
| Brodie, MJ; McKee, PJ; Percy-Robb, I | 1 |
| Peichev, L | 2 |
| De Sarro, A; De Sarro, GB; Nistico', G; Trimarchi, GR | 1 |
| Patsalos, PN; Zakrzewska, JM | 1 |
| Colombo, JP; Straver, JS; van der Vijver, JC; van Woerkom, TC; Verbiest, HB | 1 |
| Akpolat, T; Caglar, S; Sungur, A; Sungur, C; Turgan, C; Yasavul, U | 1 |
| Leppik, IE | 4 |
| Fujii, T; Ito, M; Mikawa, H; Nozaki, K; Okuno, T; Shirasaka, Y | 1 |
| Theodore, WH | 1 |
| Churchyard, A; Grainger, K; Khangure, M | 1 |
| Baruzzi, A; Di Sarro, R; Gallassi, R; Lugaresi, E; Marra, M; Morreale, A | 1 |
| Hönack, D; Löscher, W | 1 |
| Cavalheiro, EA; Dziki, M; Kleinrok, Z; Parada, J; Turski, W | 1 |
| Bonneton, J; Dravet, C; Genton, P; Mesdjian, E; Roger, J; Sennoune, S | 1 |
| Cheymol, G; Lebot, M; Poirier, JM | 1 |
| Morris, RG; Sallustio, BC | 1 |
| Rainey, JE; Schaumann, BA; Taylor, K; Tittle, TV | 1 |
| Friel, PN; McCormick, K; Yerby, MS | 1 |
| Dravet, C; Genton, P; Giraud, N; Guerrini, R; Julian, C; Legras, C; Magaudda, A; Mesdjian, E; Soulayrol, S; Trentin, G | 1 |
| Lindhout, D; Meijer, JW; Meinardi, H; Nau, H | 1 |
| Lenn, NJ; Robertson, M | 1 |
| Baba, A; Hori, T; Kawai, N; Koizumi, J; Moroji, T; Shiraishi, H; Suzuki, T; Tada, K | 1 |
| Schaumann, BA; Tittle, TV | 1 |
| Fujita, T; Takano, K; Tanaka, S; Tanaka, T; Yonemasu, Y | 1 |
| Billi, P; Broccoli, PL; Fontana, G; Melandri, R; Pezzilli, R | 1 |
| Ichikawa, Y; Nakano, M; Ohnishi, J; Tomita, S | 1 |
| Declerck, AC; Wauquier, A | 1 |
| Clarke, BM; Griffin, H; Hudoba, P; Upton, A | 1 |
| Wyllie, E; Wyllie, R | 1 |
| Burlina, A; Mould, GP; Müller, C; Stamp, RJ | 1 |
| Bermes, EW; Garbincius, J; Jandreski, MA; Shah, JC | 1 |
| Baruchello, M; Brignolio, F; Verzè, L | 1 |
| Bagri, A; Di Scala, G; Sandner, G | 1 |
| Abe, M; Endo, C; Kuroda, Y; Matsuda, Y; Neshige, R | 1 |
| Aragonés, P; De La Morena, LV; Martínez, R; Tendillo, F; Vaquero, J | 1 |
| Dickinson, SL; Jackson, HC; Nutt, DJ; Ripley, TL | 1 |
| Collins, MD; Resnick, E; Scott, WJ; Walling, KM | 1 |
| Agarwala, RK; Mehrotra, TN; Rastogi, P; Singh, VS | 1 |
| Fredow, G; Löscher, W | 1 |
| Foster, GR; Freeth, CJ; Goldin, RD; Nieman, E; Oliveira, DB | 1 |
| Berg, I; Butler, R; Forsythe, I; McGuire, R | 1 |
| Heller, AJ; Johnson, AL; Marshall, WJ; Reynolds, EH; Ring, HA | 1 |
| Huang, JD; Lai, ML; Wang, SL | 1 |
| Alonso, C; Camiña, MF; Gómez, M; Paz, JM; Rodriguez-Segade, S; Rozas, I | 1 |
| Alonso, C; Camiña, MF; Castro-Gago, M; Paz, JM; Rodriguez-Segade, S; Rozas, I | 1 |
| Ishikawa, S; Izumi, M; Okada, H; Takeda, A; Tanaka, H | 1 |
| Eadie, MJ | 2 |
| Bates, SR; Hug, G; Landrigan, EA; McGraw, CA | 1 |
| Giardina, M; Pacifici, R; Paris, L; Pichini, S; Sideri, G; Zuccaro, P | 1 |
| Higuchi, T; Kato, N; Minatogawa, Y; Nagaki, S | 1 |
| Massagli, TL | 1 |
| Holmes, GL | 1 |
| Mikati, M | 1 |
| Smith, DB | 1 |
| May, TW; Nothbaum, N; Rambeck, B | 1 |
| Albani, F; Baruzzi, A; Campostrini, R; Galli, G; Paganini, M; Riva, R; Zaccara, G | 1 |
| Bartels, H; Hebestreit, H; Mingers, AM; Pannenbecker, J | 1 |
| Fukushima, Y; Hirano, T; Kaneko, S; Kondo, T; Otani, K | 1 |
| Collins, MD; Fradkin, R; Scott, WJ | 1 |
| Altshuler, LL; Devinsky, O; Post, RM; Theodore, W | 1 |
| Cramer, JA; Hochholzer, JM; Mattson, RH; Scheyer, RD; Toftness, BR | 1 |
| May, T; Rambeck, B | 2 |
| Aguado-Vega, M; Arranz Peña, MI; Rubí Cervino, J; Seijas Martínez-Echevarría, MV | 1 |
| Modica, PA; Spitznagel, EL; Tempelhoff, R | 1 |
| Gorman, AM; Larsson, OM; Maguire, C; Martin, ML; Regan, CM; Schousboe, A; Williams, DC | 1 |
| Ferrendelli, JA; Miller, JW | 1 |
| Miura, H | 3 |
| Briggle, TV; Guterman, A; McManus, DQ; Perchalski, R; Ramsay, RE; Vazquez, D; Wong, P; Yost, RA | 1 |
| Chen, SS; Shen, MR | 1 |
| Matisová, E; Pham Thi, Ha; Volmut, J | 1 |
| Acheampong, A; Anderson, GD; Baillie, TA; Friel, PN; Guyot, M; Levy, RH; Loiseau, P; Rettenmeier, AW; Tor, J; Wilensky, AJ | 1 |
| Ikuta, T; Ishimoto, Y; Nagamine, I; Ogawa, Y; Okura, M; Otsuka, T | 1 |
| Foley, H | 1 |
| Hope, PL; Lindenbaum, RH; Squier, W | 1 |
| Cosgrove, M; Pople, S; Wallace, SJ | 1 |
| Kahn, D; Schneier, HA | 1 |
| Jongsma, MJ; Snijders, CJ | 1 |
| Armon, C; Brown, E; Carwile, S; Miller, P; Shin, C | 1 |
| Bausch, S; Blackwood, J; Gassmann, S; Grün, K; Inbar, S; Kreider, R; Löchel, B; Siebert, M; Walter, G | 1 |
| Bun, H; Cano, JP; Durand, A; Monjanel-Mouterde, S; Noel, F | 1 |
| Jürgens, U; May, T; Rambeck, B; Schnabel, R; Villagrán, R | 1 |
| Trimble, MR | 1 |
| Blennow, G; Heijbel, J; Sandstedt, P; Tonnby, B | 1 |
| Ruser, I | 1 |
| Brodie, MJ; Butler, E; Gillham, RA; Larkin, JG; Wiedmann, KD; Williams, N | 1 |
| Aoyama, T; Higuchi, S; Hirata, K; Ichikou, N; Ieiri, I; Yamada, H | 1 |
| Aoyama, T; Higuchi, S; Hirata, K; Ieiri, I; Yamada, H | 1 |
| Macdonald, RL; McLean, MJ; Skerritt, JH | 1 |
| Garzón, P; González-Cornejo, S; Navarro-Ruiz, A; Román-Maldonado, S | 1 |
| Amin, I; Cooper, IS; Garnett, S; Nahmias, C; Springman, M; Upton, AR | 1 |
| Schauf, CL | 1 |
| Carter, BS; Stewart, JM | 1 |
| Garcia de la Serrana, H; Mota, C; Puche, E; Saucedo, R | 1 |
| Haidukewych, D; Rodin, EA; Zielinski, JJ | 1 |
| Adamson, AR; Brodie, MJ; Goldberg, A; Herrick, AL; McColl, KE; Moore, MR | 1 |
| Schmidt, D | 5 |
| Hawker, CS; Saxon, AJ; Whittaker, S | 1 |
| Baty, C; Jambou, J; Leducq, B; Richard, L | 1 |
| de la Peña, CA; Del Río, R; Fernandez, MP; Paz, JM; Rodriguez-Segade, S; Rozas, I; Tutor, JC | 1 |
| Büchsel, R; Kohl, D; Kreiten, K; Matern, S; Wietholtz, H; Zysset, T | 1 |
| Beastall, GH; Brodie, MJ; Larkin, JG; Macphee, GJ | 1 |
| Hayakawa, T; Matsui, Y; Mogami, H; Okamoto, Y; Shimizu, K; Tamura, K; Yamada, M | 1 |
| Bury, RW; Fullinfaw, RO; Johnson, GJ; Kilpatrick, CJ; Moulds, RF | 1 |
| Hasegawa, T; Johno, I; Kitazawa, S; Ohshima, T | 1 |
| Morrow, JI; Routledge, PA | 1 |
| Horibe, Y; Ito, Y; Iwaki, M; Ogiso, T; Yoneda, I | 1 |
| Murthy, VS; Reynolds, NC | 1 |
| Garcia de la Serrana, H; Garcia Morillas, M; Mota, C; Puche, E | 1 |
| Cennamo, M; Piccione, E; Ticconi, C | 1 |
| Franceschetti, S; Hamon, B; Heinemann, U; Konnerth, A; Yaari, Y | 1 |
| Morselli, PL | 1 |
| Iri, H; Kano, S; Kikuchi, H; Matsumoto, K; Takahashi, H; Umino, M | 1 |
| Dow, KE; Riopelle, RJ | 1 |
| Kruse, HJ; Kuch, H | 1 |
| Reynolds, EH; Trimble, MR | 1 |
| Clayton, RM; Sedowofia, SK | 1 |
| Macdonald, RL; McLean, MJ | 2 |
| Eluma, FO; Hayes, TG; Sucheston, ME | 1 |
| Bobele, GB; Bodensteiner, JB; Grunow, JE; Hille, MR; Marks, WA; Morris, MP; Tuggle, D | 1 |
| Samanin, R; Tullii, M; Vezzani, A; Wu, HQ | 1 |
| Hartshorn, EA; Hartshorn, JC | 1 |
| Nosek, TM | 3 |
| Lloyd, KG | 1 |
| Fahn, S | 1 |
| Kishita, C | 1 |
| Duncan, J | 1 |
| Clark, R; Picker, M; Poling, A; Vande Polder, D | 1 |
| Gal, J; Molitoris, BA; Nakata, LM; Sedman, AJ | 1 |
| Buchanan, N | 1 |
| Ahmad, SN; Jaffery, NF; Jailkhani, BL | 1 |
| Hudson, JI; Pope, HG | 1 |
| Berry, DJ; Newbery, JE; Pettit, LI; Streete, JM | 1 |
| Callaghan, N; Casey, C; Goggin, T | 1 |
| Endsley, B; Leibold, L; Picker, M; Poling, A | 1 |
| Blakely, E; Picker, M; Poling, A; White, W | 1 |
| Baker, M; Bissessar, A; Callaghan, N; Crowley, M; Goggin, T; Gough, H | 2 |
| Baciewicz, AM | 1 |
| Vaĭntrub, MIa | 1 |
| Belknap, JK; Crabbe, JC; Kosobud, A; Laursen, SE; Tam, B; Young, ER | 1 |
| Lee, EK; Walters, JR; Waszczak, BL | 1 |
| Dam, M; Pedersen, B | 1 |
| Mondadori, C; Schmutz, M | 1 |
| de la Iglesia, FA; DiFonzo, CJ; Martin, RA; Sturgess, JM; Walker, RM | 1 |
| Karas, CA; Picker, M; Poling, A | 1 |
| Chadwick, D; Crawford, P | 1 |
| Freed, WJ; Schwarz, SS | 1 |
| Ala-Houhala, M; Koivikko, M; Koivula, T; Korpela, R; Koskinen, M; Koskinen, T | 1 |
| Shinnar, S | 1 |
| Haidukewych, D; John, G | 1 |
| Castaño, C; Durá, T; Juste, M; Moya, M; Muñoz, M | 1 |
| Bittencourt, PR; Gorz, AM; Silvado, CE | 1 |
| Bertollini, R; Källen, B; Mastroiacovo, P; Robert, E | 1 |
| Trimble, R | 1 |
| Ballinger, BR; Fenton, GW; Sheppard, LC | 1 |
| Deguchi, Y; Ichimura, F; Nakashima, E; Yokogawa, K | 1 |
| Dreifuss, FE; Langer, DH | 1 |
| Aguzzi, F; Attardo-Parrinello, G; Crema, F; Fratino, P; Gatti, G; Perucca, E | 1 |
| Belal, MS; Harvey, W; Robinson, PB | 1 |
| Callaghan, N; Garrett, A; Goggin, T | 1 |
| de Voogd-van der Straaten, I; Neef, C | 1 |
| Borsey, DQ; Browning, MC; Connacher, AA; Davidson, DL; Jung, RT | 1 |
| Bachmann, KA; Jahn, D; Schwartz, J; Yang, C | 1 |
| Mimaki, T; Onoe, S; Seino, Y; Yabuuchi, H; Yamaoka, K; Yamashita, G | 1 |
| Alexianu, M; Dan, A; Vasilescu, C | 1 |
| Baillie, TA; Boberg, M; Rettenmeier, AW; Rettie, AE | 1 |
| Campanella, G; Capone, D; De Marino, V; Del Rio, A; Pisanti, N | 1 |
| Krall, RL; Resor, SJ | 1 |
| Berlit, P; Krause, KH; Schellenberg, B; Schmidt-Gayk, H | 1 |
| Duncan, JS; Shorvon, SD; Trimble, MR | 1 |
| Lindhout, D; Reuss, A; Sachs, ES; Stewart, PA; van Swaay, E; Wladimiroff, JW | 1 |
| Bourgeois, BF | 3 |
| Hess, CW | 1 |
| Miles, MV; Snead, OC; Thorn, MD | 1 |
| Campos Junior, Sda S; Damasceno, BP; de Melo-Souza, SE; Martins, LF | 1 |
| Bury, RW; Fullinfaw, RO; Kilpatrick, CJ; Moulds, RF | 1 |
| Kuhnz, W; Löscher, W; Nau, H | 1 |
| Culshaw, MA; Evans, S; Lewis-Jones, MS | 1 |
| Piredda, SG; Swinyard, EA; Woodhead, JH | 1 |
| Chadwick, DW; Howel, D; Rawlins, MD; Turnbull, DM | 1 |
| Albani, F; Ambrosetto, G; Baruzzi, A; Contin, M; Gobbi, G; Perucca, E; Procaccianti, G; Riva, R; Santucci, M | 1 |
| Fromm, GH | 1 |
| Koch, C; Picker, M; Poling, A; Thomas, J | 1 |
| Depaulis, A; Marescaux, C; Micheletti, G; Reis, J; Rumbach, L; Vergnes, M; Warter, JM | 1 |
| Hackenberg, K; Rengeling, M; Rühl, G; Zäh, W | 1 |
| Levy, RH; Yerby, MS | 1 |
| Brandt, C; Chabrier, G; Imler, M; Marescaux, C; Micheletti, G; Rumbach, L; Warter, JM | 1 |
| Alvarez, N | 1 |
| Dailey, JW; Jobe, PC | 1 |
| Bittencourt, PR; Richens, A | 1 |
| Ishizaki, T; Kushida, K | 1 |
| Burke, JT; Thénot, JP | 1 |
| Seymour, RA; Smith, DG; Turnbull, DN | 1 |
| Greene, SH; Lisk, DR | 1 |
| Arnetoli, G; Bartelli, M; Campostrini, R; Messori, A; Moroni, F; Paganini, M; Valenza, T; Zaccara, G; Zappoli, R | 1 |
| Canevini, MP; Canger, R; Cornaggia, C; Giuccioli, D; Pinelli, P; Pruneri, C | 1 |
| Callaghan, N; Crowley, M; Goggin, T; Kenny, RA; O'Neill, B | 1 |
| Picker, M; Poling, A; White, W | 1 |
| Burgess, RJ; Drake, ME; Paulson, GW | 1 |
| Declerck, AC; Martens, WL; Wauquier, A | 1 |
| Haidukewych, D; John, G; Rodin, EA; Zielinski, JJ | 1 |
| Frey, HH; Löscher, W | 1 |
| Brodie, MJ | 2 |
| Freeman, JM; Vining, EP | 2 |
| Abbott, LC; Bennett, GD; Finnell, RH; Taylor, SM | 1 |
| Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y | 1 |
| Beran, RG; Lewis, JH; Nolte, JL; Westwood, AP | 1 |
| Carpenter, CL; Cooper, EC; Greenberg, DA | 1 |
| Tollefson, G | 1 |
| Alterthum, K; Bauer, P; Stünkel, S; Windorfer, A | 1 |
| Kosoĭ, MIu | 1 |
| Maheshwari, MC | 1 |
| Battistin, L; Bracco, F; Gabana, MA; Maggioni, F; Saladini, M; Zanchin, G | 1 |
| Pei, YQ | 1 |
| de Wolff, FA; Peters, AC; van Kempen, GM | 1 |
| Deisenhammer, E; Schwarzbach, H; Sommer, R | 1 |
| Ito, K; Murata, T; Nioka, M; Owada, E; Sato, J | 1 |
| Neuvonen, PJ; Tokola, RA | 1 |
| Hosokawa, K; Kugoh, T | 1 |
| Berkovic, SF; Bladin, PF; Jones, DB; Smallwood, RA; Vajda, FJ | 1 |
| Boréus, LO; Lundberg, B; Nergårdh, A | 1 |
| Monninger, P; Przuntek, H | 1 |
| Berlit, P; Krause, KH; Rascher, W | 1 |
| Mantegazza, P; Martini, A; Panerai, AE; Sacerdote, P | 1 |
| Hobusch, D; Külz, J | 1 |
| Kiul'ts, I; Klaĭf, F | 1 |
| Crosland, MB; Nosek, TM | 1 |
| Göpfert-Geyer, I; Hartmann, A; Helge, H; Huth, H; Jäger-Roman, E; Jakob, S; Koch, S; Rating, D | 1 |
| Friel, PN; Koch, KM; Levy, RH; Lockard, JS; Maris, DO | 1 |
| Baars, AM; van der Dries, A; van der Kleijn, E; Vree, TB | 1 |
| Bruckner, A; Henneberry, RC; Lee, YJ; O'Shea, KS | 1 |
| Crawford, KD; Crawford, RD; Johnson, DD | 1 |
| Rowan, AJ | 1 |
| Berry, DJ; Volans, GN; Wiseman, HM | 1 |
| Bruni, J; Somerville, ER | 1 |
| Crema, A; Perucca, E | 1 |
| Friis, ML | 1 |
| Sonawane, BR; Yaffe, SJ | 1 |
| Hammond, EJ; Karas, BJ; Marquardt, K; Murphy, JV; Ramsay, RE; Wilder, BJ | 1 |
| Cloyd, JC; Graves, NM; Welty, TE | 1 |
| Farrell, K; Godolphin, W; Trepanier, J | 1 |
| Buss, DC; Richens, A; Rimmer, EM; Routledge, PA | 1 |
| Bleck, TP | 1 |
| Asconapé, J; Penry, JK | 1 |
| Holtzman, D; Olson, JE; Scher, MS | 1 |
| Reynolds, EH | 1 |
| Post, RM; Uhde, TW | 1 |
| Blanco Fernández-Mayoralas, P; Galván Arrieta, R; González González, A; López Zanón, A | 1 |
| Callaghan, N; Keating, J; O'Dwyer, R | 1 |
| Albright, PS; Bruni, J | 2 |
| Perucca, E | 3 |
| Frey, HH; Löscher, W; Reiche, R; Schultz, D | 1 |
| Levy, RH; Moreland, TA | 1 |
| Bentsen, KD; Gram, L | 2 |
| Ramsay, RE | 1 |
| Duwe, K; Kuhnz, W; Nau, H; Wittfoht, W | 1 |
| Holtzman, JL | 1 |
| Koryntová, H; Mares, P; Maresová, D; Pohl, M; Seidl, J; Velísek, L | 1 |
| Alván, G; Palm, R; Silseth, C | 1 |
| Battistin, L; Berlese, G; Roman, G; Varotto, M | 1 |
| Helge, H; Jäger-Roman, E; Kuhnz, W; Nau, H; Rating, D | 1 |
| Classen, W; Mondadori, C | 1 |
| Dam, M | 2 |
| Allen, J; Perucca, E; Richens, A; Routledge, PA; Tsanaclis, LM | 1 |
| McLean, S; Millingen, KS; Peterson, GM | 1 |
| Kutt, H | 1 |
| Picker, M; Poling, A | 1 |
| Amano, K; Iseki, H; Kakinoki, Y; Kawabatake, H; Kawamura, H; Kitamura, K; Nagao, T; Notani, M; Shiwaku, T; Tanikawa, T | 1 |
| Felding, I; Rane, A | 1 |
| Berrettini, W; Kellner, C; Post, RM; Uhde, TW | 1 |
| Porter, RJ; Theodore, WH | 1 |
| Hedges, A; Makki, KA; Perucca, E; Richens, A; Ruprah, M; Wilson, JF | 1 |
| Alonso, RJ; Covington, TR; Mancall, EL | 1 |
| De Paiva, VJ; Subirana, A; Subirana, M | 1 |
| Breese, GR; Frye, GD; Greenwood, RS; McCown, TJ | 1 |
| Ashok, PP; Maheshwari, MC | 1 |
| Eluma, FO; Hayes, TG; Paulson, RB; Sucheston, ME | 1 |
| Butlin, AT; Cook, ML; Danta, G | 2 |
| Forsythe, WI; Sills, MA | 1 |
| Lajtha, A; Toth, E | 1 |
| Deisenhammer, E; Nitsche, V; Sommer, R | 1 |
| Tift, JP | 1 |
| Swerdlow, M | 1 |
| Franco-Morselli, R; Morselli, PL | 1 |
| Haidukewych, D; Rodin, EA | 3 |
| Kirkham, DB; Reynolds, NC | 1 |
| Kober, A; Olsson, Y; Sjöholm, I | 1 |
| Bruni, J; Gallo, JM; Lee, CS; Perchalski, RJ; Wilder, BJ | 1 |
| Beran, RC; Sansom, LN; Schapel, GJ | 1 |
| Crema, A; Frigo, GM; Gatti, G; Hebdige, S; Lecchini, S; Perucca, E | 1 |
| Kingsley, E; Tolman, KG; Tweedale, R | 1 |
| Rentz, R | 1 |
| Quednow, B; Walther, H | 1 |
| Fröscher, W | 1 |
| Paulson, GW; Paulson, RB | 1 |
| Koch, KM; Levy, RH; Ludwick, BT | 1 |
| Johnson, RH; Lambie, DG; Melville, ID; Nanda, RN; Shakir, RA | 1 |
| Chattha, AS; Fromm, GH; Glass, JD; Martinez, AJ | 1 |
| O'Leary, TD; Sansom, LN | 1 |
| Freeman, JM; Johnston, MV | 1 |
| Berchou, RC; DeSousa, G; Haidukewych, D; Lodhi, R; Rodin, EA | 1 |
| Di Perri, RG; Pisani, FD | 1 |
| Aminoff, MJ | 1 |
| Marumo, H; Ohmori, K; Shuto, K; Yamanami, S | 1 |
| Di Perri, R; Pisani, F | 2 |
| Perucca, E; Richens, A; Ruprah, M | 1 |
| Dreifuss, FE; Penry, JK; Sackellares, JC; Sato, S | 1 |
| Bustamante, L; Goldensohn, ES; Lueders, H; Pippenger, C | 1 |
| Kulik, FA; Wilbur, R | 1 |
| Scollo-Lavizzari, G | 1 |
| Fuller, TA; Olney, JW | 1 |
| Tollefson, GD | 1 |
| Hamshaw-Thomas, A; Knott, C; Reynolds, F | 1 |
| Majkowski, J; Pisarski, W; Tokarz, A; Woźniak, J | 1 |
| Laidlaw, J; Makki, K; Monks, A; Oxley, J; Richens, A | 1 |
| Cundill, JG; Swerdlow, M | 1 |
| Goodey, RJ | 1 |
| Dam, M; Philbert, A | 1 |
| Kulig, BM | 1 |
| Chadwick, DW; Rawlins, MD; Turnbull, DM; Weightman, D | 1 |
| Levy, RH; Ojemann, LM; Patel, IH; Venkataramanan, R; Viswanathan, CT | 1 |
| Coquillat, G; Kurtz, D; Marescaux, C; Micheletti, G; Rumbach, L; Warter, JM | 1 |
| Clifford, DB; Dodson, WE; Ferrendelli, JA; Lothman, EW | 1 |
| Butlin, AT; Danta, G; Wolfendale, L | 1 |
| Cohan, SL | 1 |
| Chiba, K; Ishizaki, T; Tabuchi, T; Wagatsuma, T; Yokochi, K | 1 |
| Patsalos, PN; Wiggins, RC | 1 |
| Cohn, DF; Homonnai, ZT; Paz, GF | 1 |
| Keys, PA | 1 |
| Asconapé, JJ; Penry, JK | 1 |
| Chiba, K; Ishizaki, T; Nakazawa, Y; Tabuchi, T; Wagatsuma, T | 1 |
| Koch, KM; Levy, RH | 1 |
| Höjer, B; Rane, A | 1 |
| Kakegawa, N; Seino, M | 1 |
| Congdon, WC; DuCharme, LL; Levy, RH; Lockard, JS | 1 |
| Kido, H | 1 |
| Harris, M; Harvey, W; Papadogeorgakis, N; Robinson, PB | 1 |
| Hitchcock, E; Teixeira, M | 1 |
| Monks, A; Richens, A | 1 |
| Bleck, TP; Chang, CW | 1 |
| Hjelm, M; Ratnaraj, N | 1 |
| Cloyd, J; Garnett, WR; Holmes, GL; Meyer, MC; Schiffer, JR | 1 |
| Hayashi, A; Ishii, K; Mizusawa, H; Shoji, S; Tamaoka, A; Usuki, S | 1 |
| Auchus, AP; Freeman, A; Green, RC | 1 |
| Carroll, D; Jadad, AR; McQuay, H; Moore, A; Wiffen, P | 1 |
| Qu, ZP | 1 |
| Arai, H; Itagaki, Y; Kodaka, R; Mano, T; Matsuoka, T; Nagai, T; Okada, S; Ono, J; Suzuki, Y | 1 |
| Parmeggiani, A; Posar, A; Riva, R; Rossi, PG | 1 |
| García-Teno, M; González-Darder, JM | 1 |
| Durkin, MW; Gallagher, BB; King, DW; Loring, DW; Meador, KJ; Moore, EE; Nichols, ME; Oberzan, RE; Thompson, WO | 1 |
| Amano, T; Fujita, Y; Hanaya, R; Matsubayashi, H; Sasa, M; Serikawa, T; Ujihara, H; Uozumi, T | 1 |
| Graves, NM; Kerrick, JM; Wolff, DL | 1 |
| Bayer, A; Paulus, W; Ried, S; Schmidt, D; Thiel, HJ; Zrenner, E | 1 |
| Castro-Lopes, JM; Evan, G; Schadrack, J; Tölle, TR; Zieglgänsberger, W | 1 |
| May, T; Wohlhüter, M; Wolf, P | 1 |
| Chadwick, D; Chesterman, P; Crawford, P; Elwes, RD; Heller, AJ; Johnson, AL; Reynolds, EH | 1 |
| Aldenkamp, AP; Alpherts, WC; Blennow, G; Elmqvist, D; Heijbel, J; Nilsson, HL; Sandstedt, P; Tonnby, B; Wåhlander, L; Wosse, E | 2 |
| Korinthenberg, R; Wehrle, L; Zimmerhackl, LB | 1 |
| Yerby, MS | 1 |
| Chetty, M | 1 |
| Buchanan, N; Sharpe, C | 1 |
| Becker, A; Grecksch, G; Ostner, C; Piönnigs, B | 1 |
| Couper, J | 1 |
| Callaghan, N; Majeed, T; O'Connell, A; Oliveira, DB | 1 |
| Cloyd, JC; Lackner, TE; Leppik, IE | 1 |
| Cai, Z; Liu, XM; Ruan, XZ; Zhu, SQ | 1 |
| Hekster, YA; Keyser, A; Lammers, MW; Meinardi, H; Renier, WO; van Lier, H; Wijsman, DJ | 1 |
| Bordiukov, MM; Nikushkin, EV | 1 |
| Furui, T; Murakami, A | 1 |
| Duncan, JS; Patsalos, PN; Reutens, DC | 1 |
| Blacklaw, J; Brodie, MJ; Connelly, D; Forrest, G; Gillham, RA; McKee, PJ; Walker, SM | 1 |
| Bourgeois, BF; Chez, MG; Knowles, WD; Pippenger, CE | 1 |
| Doucet, J; Fresel, J; Hue, G; Moore, N | 1 |
| Martin, PJ; Millac, PA | 1 |
| Acheampong, AA; Anderson, GD; Levy, RH | 1 |
| Chadwick, D | 2 |
| Borowicz, K; Czuczwar, SJ; Kleinrok, Z; Kozicka, M | 1 |
| Hönack, D; Löscher, W; Rundfeldt, C | 1 |
| Baba, H; Ono, K; Sugai, S | 1 |
| Clavería, LE; Coria, F; Duarte, J; Fernandez, E; Macias, S | 1 |
| Berg, I; Butler, A; Ellis, M; Foster, J | 1 |
| Bachmann, KA; Jauregui, L | 1 |
| Huang, JD; Lai, ML | 1 |
| Brodie, AF; Brodie, MJ; Larkin, JG; McKee, PJ; Percy-Robb, IW | 1 |
| Morrow, J; Sharpe, PC; Trimble, ER | 1 |
| Andersson, A; Berggren-Söderlund, M; Fex, G; Larsson, K | 1 |
| Botha, JH; Gray, AL; Miller, R | 1 |
| Darsot, S; Doheny, MH; Elyas, AA; O'Connell, MT; Patsalos, PN; Ratnaraj, N | 1 |
| de Silva, M; Hughes, E; Johnson, AL; MacArdle, B; McGowan, M; Neville, BG; Reynolds, EH; Stewart, J | 1 |
| Kubova, H; Lanstiakova, M; Mares, P; Mockova, M; Vorlicek, J | 1 |
| Binder, LM; Oken, BS; Salinsky, MC | 1 |
| DeCarli, C; Fazilat, S; Gaillard, WD; Theodore, WH; Zeffiro, T | 1 |
| Hirohashi, M; Kitano, Y; Nomura, M; Takasuna, K; Usui, C | 1 |
| Gargallo Fernandez, MA; Gonzalez, IG; Marcos Martinez, L; Martin Luquero, M | 1 |
| Bernácer Alpera, B; Ferrer Tuset, C; López Alemany, M | 1 |
| Myer, EC; Tam, DA | 1 |
| Aguglia, U; De Sarro, A; De Sarro, G; Nava, F | 1 |
| Kitagawa, Y; Niwa, K; Shinohara, Y; Yoshii, F | 1 |
| Marsden, CA; Martin, KF; Rowley, HL | 1 |
| Akaho, R | 1 |
| Kelly, KM; Macdonald, RL | 1 |
| Ashikari, Y; Chiba, S; Kodama, Y; Kuranari, M; Sakata, T; Takeyama, M | 1 |
| Helge, H; Jäger-Roman, E; Koch, S; Lösche, G; Nau, H; Rating, D | 1 |
| George, B; Kulkarni, SK | 1 |
| Akita, M; Hasegawa, M; Hasegawa, T; Nabeshima, T; Shinoda, M | 1 |
| Perucca, E; Pisani, F; Spina, E | 1 |
| Jürgens, U; May, TW; Rambeck, B | 1 |
| Henskens, YM; Nieuw Amerongen, AV; Strooker, H; van den Keijbus, PA; Veerman, EC | 1 |
| De Bruijn, EA; Highley, MS | 1 |
| Wilder, BJ | 1 |
| Murakami, K; Muro, H; Nishida, N; Sugimoto, T; Woo, M | 1 |
| Banu, K; Ratnam, RS; Thilothammal, N | 1 |
| Armand, V; Louvel, J; Pumain, R; Ronco, G; Villa, P | 1 |
| Diomedi, M; Gigli, GL; Masala, C; Placidi, F; Pomponi, MG; Scalise, A; Silvestri, G | 1 |
| Czuczwar, SJ; Gasior, M; Kleinrok, Z; Kozicka, M; Pietrasiewicz, T; Turski, WA | 1 |
| Cox, S; Dusci, LJ; Kelley, MT; Walson, PD | 1 |
| Crossey, MJ; Dasgupta, A | 1 |
| Scriba, GK | 1 |
| Chan, HL; Tan, KC | 1 |
| Brown-Croyts, LM; Ko, GY; Teyler, TJ | 1 |
| Martínez Bermejo, Z; Pascual-Castroviejo, I | 1 |
| Morton, LD; Pellock, JM; Rizkallah, E | 1 |
| Borowicz, KK; Czuczwar, SJ; Gasior, M; Kleinrok, Z | 1 |
| Bayer, AU; Dichgans, J; Kuehn, M; Paulus, W; Ried, S; Schmidt, D; Thiel, HJ; Zrenner, E | 1 |
| Chapman, DP; Giles, WH | 1 |
| Applegate, CD; Ozduman, K; Samoriski, GM | 1 |
| Borowicz, KK; Czuczwar, SJ; Kleinrok, Z | 1 |
| Bartsch, R; Engel, J; Rostock, A; Rundfeldt, C; Tober, C; Unverferth, K; White, HS; Wolf, HH | 1 |
| Stern, RS; Tennis, P | 1 |
| Coyle, TE; Hurteau, TE; Lehmann, DF; Newman, N | 1 |
| Banfield, CR; Glue, P; Levy, RH; Mather, GG; Perhach, JL; Racha, JK | 1 |
| Rantala, H; Tarkka, R; Uhari, M | 1 |
| Dasgupta, A; McLemore, JL | 1 |
| Bazil, CW; Pedley, TA | 1 |
| Dichgans, J; Ständer, M; Weller, M | 1 |
| Balakrishnan, S; Bhargava, VK; Pandhi, P | 1 |
| Luer, MS; Winkler, SR | 1 |
| Haller, JS; Kennedy, BT | 1 |
| Balakrishnan, S; Pandhi, P | 2 |
| Ericson, M; Ihrman, C; Lindblad, LE; Tomson, T | 1 |
| Boothe, DM | 1 |
| Fukazawa, T; Hata, Y; Kino, K; Naitoh, M; Sawabe, M; Takemura, T; Tanaka, Y; Tsuru, M; Watanabe, K | 1 |
| Albus, H; Williamson, R | 1 |
| Ansakorpi, H; Isojärvi, JI; Myllylä, VV; Repo, M; Suominen, K; Tolonen, U | 1 |
| Borowicz, KK; Czuczwar, SJ; Kleinrok, Z; Starownik, R | 1 |
| Bates, D; Privitera, M; Warner, A | 1 |
| Berlinghieri, MC; David, E; De Sarro, GB; Dominijanni, A; Elia, M; Gulletta, E; Musumeci, SA | 1 |
| Anderson, GD | 1 |
| Fiechtner, HB | 1 |
| Brodie, MJ; Paul, A; Read, CL; Sills, GJ; Stephen, LJ; Stolarek, IH | 1 |
| Czuczwar, SJ; Dziki, M; Kaminski, R; Kleinrok, Z; Kozicka, M; Parada-turska, J; Turski, WA | 1 |
| Jones, AL; Proudfoot, AT | 1 |
| Caldiroli, E; Cosentino, M; De Ponti, F; Fietta, AM; Frigo, GM; Lecchini, S; Marino, F; Mazzone, A; Zibetti, A | 1 |
| David, J; Joseph, S; Joseph, T | 1 |
| Chang, GY; Gilliam, F; Messenheimer, J; Nyberg, J; Risner, ME; Rudd, GD; Sackellares, JC; Vazquez, B | 1 |
| Knowles, SR; Oh, PI; Schlienger, RG; Shear, NH | 1 |
| Hagan, RM; Higgins, GA; Kirkby, D; Southam, E | 1 |
| Danhof, M; Della Paschoa, OE; Hamstra, R; Kruk, MR; Voskuyl, RA | 1 |
| Blankenhorn, V; Jürgens, U; Jürges, U; May, TW; Rambeck, B | 1 |
| Donnelly, A; Potter, JM | 1 |
| Cano, MD; Peña-Bernal, M; Pita-Calandre, E; Rodríguez-López, CM | 1 |
| Arroyo, S; Martínez, I; Ribalta, T; Rumiá, J | 1 |
| Danhof, M; Della Paschoa, OE; Voskuyl, RA | 1 |
| Fiehn, W; Kohl, B; Rieser, PA; Ringleb, P; Schwaninger, M; Walter-Sack, I; Winter, R | 1 |
| Afifi, AH; El Desoky, E; Kandil, MR; Mostafa, OA | 1 |
| Böttiger, Y; Ståhle, L; Svensson, JO | 1 |
| López, L; Rabinowicz, AL; Thomson, A | 1 |
| Hamer, HM; Morris, HH | 1 |
| Bernstein, P; Faught, RE; Holmes, GL; Magnus-Miller, L; McLean, MJ; Morrell, MJ; Privitera, MD; Rose-Legatt, A; Willmore, LJ | 1 |
| Fukuhara, N; Ishida, C | 1 |
| Chow, L; Dasgupta, A; Wells, A | 1 |
| Soldin, SJ | 1 |
| Adèr, HJ; Beenen, LF; Heimans, JJ; Kasteleijn-Nolst Trenité, DG; Lindeboom, J; Snoek, FJ; Touw, DJ; van Alphen, HA | 1 |
| Avanzini, G; Battino, D; Canevini, MP; Canger, R; Fumarola, C; Granata, T; Guidolin, L; Hassibi, P; Mamoli, D; Molteni, F; Palmieri, C; Pardi, G; Vignoli, A; Zamperini, P | 1 |
| Anderson, GD; Awan, A; Cohen, W; Dikmen, SS; Holmes, MD; Nelson, P; Newell, DW; Temkin, NR; Wilensky, AJ; Winn, HR | 1 |
| Deckert, J; Retz, W; Supprian, T | 1 |
| Loiseau, PJ | 1 |
| Czuczwar, SJ; Haberek, G; Kleinrok, Z; Matyska, J; Pilip, S; Tomczyk, T; Turski, WA; Urbanska, EM | 1 |
| Albani, F; Baruzzi, AA; Contin, M; Riva, R | 1 |
| Hadeishi, H; Hayashi, T; Kawamura, S; Nonoyama, Y; Suzuki, A; Yasui, N | 1 |
| Alkadhi, KA; Otoom, SA | 1 |
| Braddock, SR; Gigantelli, JW; Johnson, LN | 1 |
| Alves, ND; de Carvalho, AM; de Castro-Costa, CM; Santos, FJ; Silveira, DG | 1 |
| Goldin, AL; Mclean, TH; Pugsley, MK; Yu, EJ | 1 |
| Brückner, C; Heinemann, U | 1 |
| Carwile, ST; Husain, AM; Miller, PP; Radtke, RA | 1 |
| Apeland, T; Kristensen, O; Mansoor, MA; Strandjord, RE | 1 |
| Diagne, M; Farnarier, G; Gueye, L; Mesdjian, E; Ndiaye, IP; Sene, F; Sene, MC | 1 |
| Anderson, GD; Fischer, JH; Lin, Y; Temkin, NR; Winn, HR | 1 |
| Dean, JC; Glover, S; Lloyd, DJ; Montgomery, T; Moore, SJ; Quinn, A; Turnpenny, P | 1 |
| Andermann, F; Bastos, A; D'Agostino, MD; Dubeau, F; Fedi, M | 1 |
| Chan, AW; Lai, CK; Lau, KK | 1 |
| Besag, FM | 1 |
| Bishop, J; Takhar, J | 1 |
| Canal, ML; Carvajal, J; Hernández, ER; Pedrera, JD; Postigo, S; Rico, H; Villa, LF | 1 |
| Akasaki, Y; Hashiguchi, W; Nagatomo, I; Takigawa, M; Tominaga, M; Uchida, M | 1 |
| Harden, CL | 1 |
| Jagoda, A; Yoon, Y | 1 |
| Chen, C; Guo, YC; Kwan, SY; Liu, LT; Shih, YH; Yen, DJ; Yiu, CH; Yu, HY | 1 |
| Bachański, M; Jóźwiak, S; Karkowska, B; Kmieć, T; Kuczyński, D | 1 |
| Coull, BA; Harvey, EA; Hayes, AM; Holmes, LB; Huntington, KB; Khoshbin, S; Ryan, LM | 1 |
| De Smet, R; Dhondt, A; Duym, P; Lameire, N; Lesaffer, G; Liebich, H; Van Kaer, J; Vanholder, R; Verstraete, A | 1 |
| Kruger, M; Mieczkowski, T; Psillakis, T; Tsatsakis, AM | 1 |
| Bergman, U; Diwan, V; Farahmand, BY; Nilsson, L; Persson, PG; Tomson, T | 1 |
| Fiallos, MR; Hanhan, UA; Orlowski, JP | 1 |
| Temkin, NR | 1 |
| Langendorf, F | 1 |
| Jacoby, A; Porter, E; Richens, A; Roberts, C; Roland, M; Russell, I; Thapar, A; Wall, S | 1 |
| Marson, AG; Tudur Smith, C; Williamson, PR | 1 |
| Chappell, V; Collings, J; Crawford, P; Hall, W; Stewart, A | 1 |
| Bough, KJ; Eagles, DA | 1 |
| Autret-Leca, E; Jonville-Bera, AP; Ployet, JL | 1 |
| Belmaker, RH; Einat, H; Shaldubina, A; Shimon, H; Szechtman, H | 1 |
| Barter, P; Dean, JC; Glover, SJ; Hart, J; Moore, SJ; Quinn, AG; Turnpenny, PD | 1 |
| Laskowska, M; Leszczyńska-Gorzelak, B; Oleszczuk, J | 1 |
| Albani, F; Avoni, P; Baruzzi, A; Contin, M; Riva, R | 1 |
| Bouw, J; Steijns, LS; van der Weide, J | 1 |
| Covington, EC | 1 |
| Claassen, J; Hirsch, LJ | 1 |
| Annesley, TM; Frank, EL; Juenke, J; Roberts, WL; Schwarz, EL | 1 |
| Bellomo, R; Bordoni, V; D'Intini, V; Dall'Olio, G; Galloni, E; Reiter, K; Ricatti, MG; Ronco, C; Ruperti, S; Soffiati, G; Soli, M | 1 |
| Farber, NB; Heinkel, C; Jiang, XP; Nemmers, B | 1 |
| Holmes, LB | 1 |
| Wang, MF | 1 |
| Rekling, JC | 1 |
| Lerner, AJ; Maddux, BN; Sagar, SM; Suarez, JI; Ubogu, EE; Werz, MA | 1 |
| Al-Beshri, M; AL-Ghamdi, HA; EL Desoky, ES; Halaby, FH | 1 |
| Al Homrany, M; Hamdi, AA; Irshaid, YM | 1 |
| Araki, H; Futagami, K; Gomita, Y; Hashimoto, Y; Kawasaki, H | 1 |
| Balit, CR; Dawson, A; Isbister, GK; Whyte, IM | 1 |
| Manno, EM | 1 |
| Angehagen, M; Ben-Menachem, E; Hansson, E; Rönnbäck, L | 1 |
| Esiobu, N; Hoosein, N | 1 |
| Jones, NS; Majumdar, S; McKerrow, WS; Scadding, G | 1 |
| Martín, ED; Pozo, MA | 1 |
| Affolter, N; Krähenbühl, S; Schlienger, RG | 1 |
| Gau, CS; Lin, CJ; Liou, HH; Shyu, MK; Wu, SP | 1 |
| Kapoor, SK; Krishnan, A; Sahariah, SU | 1 |
| Fujiwara, T; Iinuma, K | 1 |
| Antonis, T; Christos, M; Chryssoula, N; Dimitrios, T; Irini, P; Konstantinos, P; Nikolaos, T; Stylianos, G | 1 |
| Meussen-Elholm, ET; Olsen, CM; Røste, LS; Taubøll, E | 1 |
| Bittigau, P; Dzietko, M; Glier, C; Ikonomidou, C; Jarosz, B; Korobowicz, E | 1 |
| Jiao, Z; Shi, XJ; Zhao, ZG; Zhong, MK | 1 |
| Hermida, J; Tutor, JC; Tutor-Crespo, MJ | 1 |
| De Sarro, G; Fischer, W; Kittner, H; Regenthal, R; Russo, E | 1 |
| Papp, Z; Török, L | 1 |
| Buchan, S; Kerr, MP; Morgan, CL | 1 |
| Borges, MA; Cendes, F; Guerreiro, CA; Marques, LH; Min, LL; Noronha, AL | 1 |
| Shorvon, SD | 1 |
| Borowicz, KK; Czuczwar, SJ; Drelewska, E; Rwiader, M | 1 |
| Driever, PH; Sander, JW; Singh, G | 1 |
| Fukuoka, N; Kimura, M; Morita, S; Tsukamoto, T; Uno, J | 1 |
| Mishchenko, AL; Morozov, GV; Semenova, NV; Slastenko, OA | 1 |
| Drazkowski, JF; Lyons, MK; Sirven, JI; Wingerchuk, DM; Zimmerman, RS | 1 |
| Bebin, EM; Burneo, JG; Miller, S; Prasad, A | 1 |
| Carney, EW; DeSesso, JM; Scialli, AR; Watson, RE | 1 |
| Doñe, S; Flaster, E; Holloway, L; Marcus, R; Morrell, MJ; Pack, AM; Randall, A; Seale, C; Shane, E | 1 |
| Adams, D; Conklin, SM; Greve, KW; Helfritz, LE; Houston, RJ; Stanford, MS; Villemarette-Pittman, NR | 1 |
| Guevara Serrano, J; Iglesias Iglesias, AA; Ortega García, MP | 1 |
| Peters, CN; Pohlmann-Eden, B | 1 |
| Messenheimer, J; Mockenhaupt, M; Schlingmann, J; Tennis, P | 1 |
| Botts, SR; Coffey, GL; de Leon, J | 1 |
| Glendenning, P; Seymour, HM | 1 |
| Aujard, Y; Livet, MO; Ponsot, G | 1 |
| Brody, SA; Geyer, MA; Large, CH; Ong, JC | 1 |
| Aoki, Y; Fujiwara, M; Okada, A; Shiomi, T | 1 |
| Alvey, CW; Bockbrader, HN; Brodie, MJ; Bron, NJ; Gibson, GL; Hounslow, NJ; Posvar, EL; Randinitis, EJ; Wesche, DL; Wilson, EA | 1 |
| Antkiewicz-Michaluk, L; Czuczwar, SJ; Luszczki, JJ | 1 |
| Gupta, RK; Tandon, VR | 1 |
| Hayashi, T; Ishii, N; Ohno, R; Yamada, T; Yoshida, S; Yoshinaga, A | 1 |
| Poon, WS; Wong, GK | 1 |
| Zenkov, LR | 1 |
| Czuczwar, SJ; Luszczki, JJ; Mohamed, M | 1 |
| Coker, I; Karaguzel, O; Ozdamar, O; Sener, U; Topbas, M; Zorlu, Y | 1 |
| Kupiec, T; Raj, V | 1 |
| Miyake, H; Nishihara, K; Tsuji, M; Tucker, A; Ukita, T | 1 |
| Bóné, B; Janszky, J | 1 |
| Kalita, J; Misra, UK; Patel, R | 1 |
| Dodson, B; McClain, CD; McManus, ML; Wolf, GK; Zurakowski, D | 1 |
| Baker, GA; Finnell, RH; Kalayjian, LA; Liporace, JD; Loring, DW; Mawer, G; Meador, KJ; Pennell, PB; Smith, JC; Wolff, MC | 1 |
| Beijnen, JH; Boogerd, W; Huitema, AD; Joerger, M; Schellens, JH; van der Sande, JJ | 1 |
| Nekrassov, V; Sitges, M | 1 |
| Bröcker, EB; Pfeuffer, P; Raith, P; Seitz, CS; Trautmann, A | 1 |
| Bidzan, L | 1 |
| Capovilla, G; Minicucci, F; Muscas, G; Perucca, E; Tinuper, P; Vigevano, F | 1 |
| Dahl, ML; Kimland, E; Tomson, T | 1 |
| Gilbert, TH; Teskey, GC | 1 |
| Kawasaki, A; Purvin, VA; Williams, PE | 1 |
| Goto, S; Ishitsu, T; Murata, T; Nakada, N; Nakagawa, K; Seo, T; Ueda, N | 1 |
| Rossetti, AO | 1 |
| Baumann, RJ; Cook, AM; Farzam, F; Kuhn, RJ; Lewis, DA; Taylor, LM | 1 |
| Bogo, MR; Bonan, CD; Bruno, AN; Cognato, Gde P; da Silva, RS; Sarkis, JJ | 1 |
| Birnbaum, AK | 1 |
| Andrade, JD; Janatova, J; Juenke, JM; McMillin, GA; Yang, X | 1 |
| Borowicz, KK; Czuczwar, SJ; Furmanek-Karwowska, K; Luszczki, JJ; Sawicka, K | 1 |
| Borowicz, KK; Czuczwar, SJ; Jaszczyk, B; Luszczki, JJ | 1 |
| Bratton, SL; Chestnut, RM; Ghajar, J; Harris, OA; Hartl, R; Manley, GT; McConnell Hammond, FF; Nemecek, A; Newell, DW; Rosenthal, G; Schouten, J; Shutter, L; Timmons, SD; Ullman, JS; Videtta, W; Wilberger, JE; Wright, DW | 1 |
| de Krom, MC; Nicolai, J | 1 |
| Anin, S; Bates, MD; Chadwick, D; Neilson, JP; Quenby, SM; Vince, GS | 1 |
| Borowicz, KK; Czuczwar, SJ; Luszczki, JJ; Malek, R; Patsalos, PN; Ratnaraj, N | 1 |
| Agarwal, P; Antony, AR; Chandra, R; Garg, N; Gupta, G; Kumar, N | 1 |
| Edelbroek, PM; Vermeij, TA | 1 |
| Gjerstad, L; Jemtland, R; Lekva, T; Melhus, G; Nissen-Meyer, LS; Reinholt, FP; Reppe, S; Solberg, LB; Svalheim, S; Taubøll, E | 1 |
| Grunze, H | 1 |
| Borowicz, KK; Czuczwar, SJ; Furmanek-Karwowska, K; Luszczki, JJ; Morawska, M | 1 |
| Banach, M; Borowicz, KK; Czuczwar, SJ; Lukasik, D; Luszczki, JJ; Zarczuk, R | 1 |
| Gazioğlu, S; Velioğlu, SK | 1 |
| Fontana, RJ; Jinjuvadia, K; Kwan, W | 1 |
| Takahashi, Y | 1 |
| Chen, LS; Courellis, SH; Gholmieh, GI | 1 |
| Farooq, MU; Gupta, R; Kassab, M; Majid, A; Reeves, M; Zemke, D | 1 |
| Liu, HY; Liu, X; Liu, XD; Liu, YC; Wang, GJ; Xie, L; Yang, HW; Zhang, DM | 1 |
| Franklin, MR; Kupferberg, HJ; Schmutz, M; Stables, JP; White, HS; Wolf, HH | 1 |
| Daugherty, J; Houry, D; Murphy, R | 1 |
| Bialer, M | 2 |
| Delima, SI; Golomb, MR; Walsh, LE | 1 |
| Liu, KT; Su, CS | 1 |
| Błaszczyk, B; Chrościńska-Krawczyk, M; Czuczwar, SJ; Jankiewicz, K | 1 |
| McMahon, DJ; Morrell, MJ; Pack, AM; Randall, A; Shane, E | 1 |
| Dardis, C; Doherty, C; Farid, S | 1 |
| Bottomley, SS; Bronze, MS; Dhaliwal, G; Jackson, R; Toubia, N | 1 |
| Lee, EL; Tor, PC | 1 |
| Kalita, J; Misra, UK; Nair, PP | 1 |
| Apeland, T; Frøyland, ES; Kristensen, O; Mansoor, MA; Strandjord, RE | 1 |
| Chiarelli, F; Manco, R; Scardapane, A; Verrotti, A | 1 |
| Churchwell, MD; Mueller, BA; Pasko, DA; Smoyer, WE | 1 |
| Dabby, R; Gilad, R; Izkovitz, N; Lampl, Y; Rapoport, A; Sadeh, M; Weller, B | 1 |
| Domínguez-Fuentes, B; García-Arjona, R; García-Gil, D; Navarro-Navarro, J; Romero-Palacios, A; Sánchez-Crespo, JM | 1 |
| Aggarwal, A; Dewan, P; Faridi, MM | 1 |
| Crooks, DP; Crozier, H; Doak, MW; Nixon, AC; Waring, WS | 1 |
| Komori, T; Mizoi, Y; Shimazu, K; Sumita, N; Tamura, N; Yamamoto, T | 1 |
| Mazoit, JX; Navarro, V | 1 |
| Baker, GA; Browning, N; Clayton-Smith, J; Cohen, M; Combs-Cantrell, DT; Kalayjian, LA; Kanner, A; Liporace, JD; Loring, DW; Meador, KJ; Pennell, PB; Privitera, M | 1 |
| Czuczwar, SJ; Kocharov, SL; Luszczki, JJ | 1 |
| Chen, X; He, L; Li, Q; Zhou, D | 1 |
| Faroongsarng, D; Kaewpibal, P; Ratanajamit, C; Setthawacharavanich, S | 1 |
| Trinka, E | 1 |
| Mula, M | 1 |
| Wang, X; Xi, Z; Yan, Y; Zeng, K | 1 |
| Baghel, R; Bala, K; Gourie-Devi, M; Grover, S; Gupta, M; Kaur, H; Kukreti, R; Sharma, S; Talwar, P | 1 |
| Abd El-Latif, HA; Abu Yossef, HA; Hassan, GS; Ragab, FA; Yahya, TA | 1 |
| Blau, N; Opladen, T; Ramaekers, VT | 1 |
| Kim, SE; Kim, SH; Kwon, OY; No, SK; Park, KM | 1 |
| Andres-Mach, M; Cioczek, JD; Kocharov, SL; Kominek, M; Luszczki, JJ; Zolkowska, D | 1 |
| Kwan, SY | 1 |
| Dahlin, MG; Ohman, I; Wide, K | 1 |
| Lang, SY; Shi, XB; Tian, HJ; Wang, RF; Wang, XQ; Yang, F | 1 |
| Gulati, S; Lodha, R; Raj, D | 1 |
| Czuczwar, SJ; Florek, M; Luszczki, JJ; Misiuta-Krzesinska, M; Tutka, P | 1 |
| Delfino, M; Elia, J; Imbrogno, N; Mazzilli, F | 1 |
| Maguire, M; Marson, AG; Ramaratnam, S | 2 |
| LaRoche, SM; Shivdat-Nanhoe, R | 1 |
| Alvarez, V; Burnand, B; Januel, JM; Rossetti, AO | 1 |
| Feuerstein, TJ; Freiman, TM; Kammerer, M; Rassner, MP | 1 |
| de Rijke, YB; van Toor, H; Visser, TJ; Visser, WE | 1 |
| Gupta, YK; Mehla, J; Pahuja, M; Reeta, KH | 1 |
| Curtis, B; Erickson, SC; Harada, AS; Le, L; Ramsey, SD; Solow, BK; Stockl, KM; Zakharyan, A | 1 |
| Li, YP; Zeng, LN; Zhang, LL | 1 |
| Kotov, AS; Rudakova, IG | 1 |
| Aggarwal, A; Mittal, H; Rai, A; Sharma, S | 1 |
| Parker, WB; Pette, GA; Siegel, MA | 1 |
| Czuczwar, SJ; Luszczki, JJ; Stepien, KM; Tomaszewski, M | 1 |
| Chan, SH; Chang, CC; Chang, WN; Chen, SD; Chuang, HY; Chuang, YC; Huang, CR; Lin, TK; Lu, CH; Tan, TY | 1 |
| Sasidaran, K; Singhi, P; Singhi, S | 1 |
| Ariyawardana, A; Pallegama, R; Ranasinghe, A; Sitheeque, M | 1 |
| Bongiovanni, LG; Brigo, F; Del Felice, A; Fiaschi, A; Storti, M | 1 |
| Chen, Z; Liu, X; Ma, M; Su, L; Wu, Y | 1 |
| Ashaye, A; Baker, EL; Baker, WL; Coleman, CI; Kluger, J; Phung, OP; Scholle, JM; Talati, R; White, CM | 1 |
| Yildiz, M | 1 |
| Birnbaum, AK; Conway, JM; Leppik, IE; Strege, MA | 1 |
| Geater, A; Limapichat, K; Phabphal, K; Sathirapanya, P; Setthawatcharawanich, S | 1 |
| Bergin, P; Jones, P; Rosemergy, I; Walker, E | 1 |
| Atli, O; Ilgin, S; Sirmagul, B | 1 |
| García-Ramos, R; Moreno Ramos, T; Porta Etessam, J; Villarejo Galende, A | 1 |
| Dhingra, K; Prakash, S | 1 |
| Akgün, H; Gökçil, Z; Odabaşi, Z; Oz, O; Yücel, M | 1 |
| Hsieh, CY; Lai, EC; Lin, SJ; Yang, YH | 1 |
| Alldredge, B; Bell, R; Bleck, TP; Brophy, GM; Claassen, J; Glauser, T; LaRoche, SM; Riviello, JJ; Shutter, L; Sperling, MR; Treiman, DM; Vespa, PM | 1 |
| Eljamel, S; Guthrie, GD | 1 |
| Bogo, MR; Bonan, CD; Nery, LR; Piato, AL; Schaefer, IC; Siebel, AM | 1 |
| Imai, K; Inoue, K; Inoue, Y; Itoh, K; Kagawa, Y; Mishima, N; Takahashi, Y; Yamamoto, Y; Yazawa, R | 1 |
| Marson, AG; Nolan, SJ; Pulman, J; Tudur Smith, C | 2 |
| Greenhalgh, J; Marson, AG; Pulman, J | 1 |
| Brizendine, CE; Naik, PJ | 1 |
| Alexander, JM; Wilson, KL | 1 |
| Berg, MJ; Braun, KP; Koudijs, SM; Malingré, MM; ter Heine, R; van der Westerlaken, MM; van Maarseveen, EM | 1 |
| Dalaklioglu, S | 1 |
| Tanaka, S; Tanaka, T | 1 |
| Broglio, KR; Connor, JT; Elm, JJ | 1 |
| Bleck, T; Chamberlain, J; Cloyd, J; Cock, H; Connor, J; Elm, J; Fountain, N; Jones, E; Kapur, J; Lowenstein, D; Shinnar, S; Silbergleit, R; Treiman, D; Trinka, E | 1 |
| Jabłoński, M; Majdan, M; Nowicka-Stążka, P; Parada-Turska, J; Rzeski, W; Turski, WA | 1 |
| Banno, Y; Funauchi, M; Kinoshita, K; Nozaki, Y; Sugiyama, M | 1 |
| Li, L; Li, WM; Wu, YH; You, Y; Zhong, ZD; Zou, P | 1 |
| Panomvana, D; Towanabut, S; Traiyawong, T | 1 |
| Chowdhury, AH; Chowdhury, RN; Ghose, SK; Habib, M; Haque, B; Hasan, AT; Hoque, A; Khan, SU; Mohammad, QD; Mondal, BA; Rahman, KM | 1 |
| Dambach, H; Faustmann, PM; Haase, CG; Hinkerohe, D; Hufnagel, A; Moinfar, Z; Prochnow, N; Stienen, MN | 1 |
| Carnevale, RC; Carvalho, IV; de Fátima Lopes Ambrósio, R; de Queiroz, RA; dos Reis, MC; Mazzola, PG; Moriel, P; Visacri, MB | 1 |
| Duncan, JS; Markoula, S; Patsalos, PN; Ratnaraj, N; Sander, JW; Teotonio, R | 1 |
| Chen, XY; He, L; Li, Q; Zhou, D | 1 |
| Kira, J; Oyagi, Y; Shigetou, H; Tateishi, T; Uehara, T; Une, H | 1 |
| Ibayashi, Y; Jotoku, H; Takahashi, M; Takasaki, M; Tanaka, H; Watanabe, K | 1 |
| Anwar, MJ; Radhakrishna, KV; Vohora, D | 1 |
| Cheuk, DK; Wong, V | 1 |
| Chiarelli, F; Cofini, M; Scaparrotta, A; Tiboni, GM; Verrotti, A | 1 |
| Anwar, MJ; Radhakrishna, KV; Sharma, A; Vohora, D | 1 |
| Hayashi, H; Imai, K; Inoue, K; Inoue, Y; Itoh, K; Miyakawa, K; Suzuki, E; Takahashi, T; Takahashi, Y; Tsuji, D; Yamamoto, Y; Yazawa, R | 1 |
| Alvariza, S; Fagiolino, P; Ibarra, M; Maldonado, C; Olano, I; Vazquez, M | 1 |
| Borowicz, KK; Borowicz, KM; Latalski, M; Zarczuk, R | 1 |
| Czuczwar, SJ; Świąder, MJ | 1 |
| Lubszky, S; Reinhart, WH; Schulzki, T; Thöny, S | 1 |
| Davis, K; Fabian, E; Greenhaw, J; Groeters, S; Herold, M; Kamp, H; Looser, R; Marxfeld, H; Mattes, W; Mellert, W; Moeller, N; Montoya-Parra, G; Prokoudine, A; Strauss, V; van Ravenzwaay, B; Walk, T | 1 |
| Deeb, S; Logan, BK; McKeown, DA; Scott, KS; Torrance, HJ; Wylie, FM | 1 |
| Hong, SB; Joo, EY; Kim, HJ; Kim, TE; Lee, SY; Seo, DW | 1 |
| Ho, PC; Kong, ST; Kumar, PK; Lee, WB; Lim, SH; Ng, YL; Wang, HY; Wong, PS | 1 |
| Gupta, YK; Katyal, J; Kumar, H | 1 |
| Bankstahl, M; Klein, S; Löscher, W | 1 |
| Buchsbaum, R; Chen, B; Choi, H; Detyniecki, K; Hirsch, LJ; Javed, A; Kato, K; Legge, A; Moeller, J | 1 |
| Chinvarun, Y; Sirisamut, T; Tantisira, MH | 1 |
| Goel, RK; Mishra, A | 1 |
| Andres-Mach, M; Baumann, MH; Luszczki, JJ; Prisinzano, TE; Zolkowska, D | 1 |
| Craner, M; Cranley, MR; McGilloway, E | 1 |
| Greenhalgh, J; Marson, AG; Weston, J | 1 |
| Afrikanova, T; Buenafe, OE; Crawford, AD; De Prins, A; de Witte, PA; Esguerra, CV; Kaminski, RM; Langlois, M; Leclercq, K; Rospo, CC; Smolders, I; Van Eeckhaut, A | 1 |
| Egusa, M; Higuchi, H; Ishii-Maruhama, M; Maeda, S; Miyawaki, T; Tomoyasu, Y | 1 |
| Babapour, V; Gavzan, H; Sardari, S; Sayyah, M | 1 |
| Florek-Luszczki, M; Glensk, M; Glowniak, K; Luszczki, JJ; Pyrka, D; Skalicka-Wozniak, K; Zagaja, M | 1 |
| Bindu, PS; Mundlamuri, RC; Nagappa, M; Prathyusha, PV; Satishchandra, P; Sinha, S; Subbakrishna, DK; Taly, AB; Umamaheswara Rao, GS | 1 |
| Chan, L; Chi, NF; Chien, LN; Chiou, HY; Hu, CJ; Huang, YH; Kuan, YC | 1 |
| Bamford, A; Clarke, A; Crowe, BH; Hacohen, Y; Lim, M; Lin, JP; Pullaperuma, SP; Sancho-Shimizu, V; Tudor-Williams, G; Vincent, A | 1 |
| Abel, H; Campbell, LA; Pohlmann-Eden, B; Thompson, K | 1 |
| Liu, DQ; Ma, HY; Sheng, YH; Wang, C; Wang, P; Yin, T; Zhou, BT | 1 |
| Kalita, J; Misra, UK | 1 |
| Hirai, K; Imai, K; Inoue, K; Inoue, Y; Itoh, K; Suzuki, E; Takahashi, T; Takahashi, Y; Tsuji, D; Yamamoto, Y | 1 |
| Belton, RJ; Lawrence, JE; Rovin, RA; Steele, CJ; Winn, RJ | 1 |
| Díaz, FV; Rasgado, LA; Reyes, GC | 1 |
| Banach, M; Borowicz-Reutt, KK; Piskorska, B | 2 |
| Bae, EK; Jang, IJ; Kim, TJ; Lee, J; Lee, KJ; Lee, SK; Moon, J; Shin, D; Shin, JW; Shin, YW | 1 |
| Barczyński, B; Czuczwar, SJ; Świąder, K; Świąder, MJ; Tomaszewski, M | 1 |
| Amaniti, E; Apostolidou, E; Karakoulas, K; Kouvelas, D; Pourzitaki, C; Tsaousi, G | 1 |
| Fagiolino, P; González, R; Guevara, N; Maldonado, C; Queijo, C; Vázquez, M | 1 |
| Fuller, HR; Garton, M; Wilson, EL | 1 |
| Abe, S; Azuma, Y; Ishihara, N; Ito, Y; Itomi, K; Kidokoro, H; Kojima, S; Kurahashi, H; Kurahashi, N; Maruyama, K; Natsume, J; Negoro, T; Okumura, A; Suzuki, M; Takeuchi, T; Tsuji, T; Watanabe, K; Yamada, K; Yamamoto, H | 1 |
| Bártfai, G; Devosa, I; Szok, D; Vanya, M | 1 |
| Marson, AG; Nolan, SJ; Tudur Smith, C; Weston, J | 1 |
| Cash, SS; Clark, SJ; Cohen, J; Cole, AJ; Deki, S; Lam, AD; Leung, EC; Lim, AS; Mantia, J; Mateen, FJ; McKenzie, ED; Nirola, DK; Patenaude, B; Thibert, R; Tshering, L; Zepeda, R | 1 |
| Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS | 1 |
| Hsieh, CY; Huang, CW; Lai, EC; Lin, SJ; Setoguchi, S; Su, CC; Yang, YK | 1 |
| Bragazzi, N; Brigo, F; Nardone, R; Trinka, E | 1 |
| Lai, EC; Shao, SC; Wu, WH; Yang, YK | 1 |
| Beydemir, Ş; Demir, Y | 1 |
| French, CR; O'Brien, TJ; Taing, KD; Williams, DA | 1 |
| Castagna, CE; Miller, AB; Poolos, NP; Story, TJ; Williams, S | 1 |
| Redecker, J; Rösche, J; Wittstock, M | 1 |
| Baldwin, R; Lumley, L; Niquet, J; Norman, K; Suchomelova, L; Wasterlain, CG | 1 |
| Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J | 2 |
| Brozmanova, H; Grundmann, M; Kacirova, I; Koristkova, B | 1 |
| Aguglia, U; Beccaria, F; Belcastro, V; Bianchi, A; Canafoglia, L; Fanella, M; Ferlazzo, E; Franceschetti, S; Gambardella, A; Granata, T; Magaudda, A; Michelucci, R; Panzica, F; Pasini, E; Riguzzi, P; Striano, P; Trentini, C | 1 |
| Bassolé, IHN; Gnankiné, O | 1 |
| Banach, M; Borowicz-Reutt, KK; Popławska, M | 1 |
| Garraghty, PE; Orczyk, JJ | 1 |
| Brown, H; Dionisio, S; Gillinder, L; Lehn, A | 1 |
| Battino, D; Bonizzoni, E; Craig, J; Lindhout, D; Perucca, E; Sabers, A; Thomas, SV; Tomson, T; Vajda, F | 1 |
| Amiri-Nikpour, MR; Bagheri, M; Dindarian, S; Eftekhari, P; Mohammadi, H; Mohammadi, S; Nazarbaghi, S | 1 |
| Dundar, Y; Greenhalgh, J; Marson, AG; Nevitt, SJ; Weston, J | 2 |
| de Baat, C; Vissink, A; Zweers, PGMA | 1 |
| Priano, J; Schiel, J; Servati, N; Vilar, J | 1 |
| Marson, AG; Nevitt, SJ; Tudur Smith, C; Weston, J | 1 |
| Franke, H; Illes, P; Khan, MT; Liu, J; Nerlich, J; Tang, Y | 1 |
| Chmielewski, J; Daniluk, J; Florek-Łuszczki, M; Karwan, S; Sawicka, KM; Wawryniuk, A; Łuszczki, JJ | 1 |
| Baker, GA; Bromley, RL; Clayton-Smith, J; Cohen, MJ; Conrad, T; Kalayjian, LA; Kanner, A; Liporace, JD; Loblein, H; Loring, DW; May, R; Meador, KJ; Pennell, PB; Privitera, M | 1 |
| Chen, CC; Chen, CT; Hsieh, PC; Lai, HY; Lee, CY; Liu, YT; Liu, ZH; Tu, PH; Wu, CT; Yeap, MC | 1 |
| Gut-Lepiech, A; Karwan, S; Kondrat-Wróbel, MW; Marzeda, P; Plech, T; Wróblewska-Łuczka, P; Łuszczki, JJ | 1 |
| Bala, K; Behgal, J; Kaushik, JS; Lather, T; Rana, R | 1 |
| Ahmed, SI; Laghari, AA; Qadeer, N; Shamim, MS | 1 |
| Faught, E; Fishman, J; Kalilani, L; Kim, H; Thurman, DJ | 1 |
| Gaínza-Lein, M; Lamb, N; Loddenkemper, T; Sánchez Fernández, I | 1 |
| Jand, A; Mousavi-Hasanzadeh, M; Palizvan, MR; Rezaeian-Varmaziar, H; Shafaat, O | 1 |
| Beran, RG; Kwok, A; Mamun, A; Sharobeam, A; Zandiehvakili, M | 1 |
| Alandas, N; Alqahtani, S; Alsultan, A | 1 |
| Agarwal, R; Kukal, S; Kukreti, R; Kushwaha, S; Rawat, C; Sharma, S; Srivastava, AK | 1 |
| Ouchi, K | 1 |
| Barsan, W; Chamberlain, JM; Cloyd, J; Cock, H; Connor, JT; Conwit, R; Elm, J; Fountain, N; Kapur, J; Lowenstein, D; Meinzer, C; Shinnar, S; Silbergleit, R | 1 |
| A S, R; Baishya, J; Jose, M; Keni, RR; Sankara Sarma, P; Thomas, SV | 1 |
| Goel, RK; Kaur, S; Sharma, NK | 1 |
| Barra, ME; Chung, DY; Phillips, KM; Rosenthal, ES | 1 |
| Kunju, PAM; Subir, HA | 1 |
| Mahadevan, S; Rameshkumar, R; Vignesh, V | 1 |
| Appleton, RE | 1 |
| Babcock, L; Barsan, W; Bleck, TP; Chamberlain, JM; Cloyd, J; Cock, H; Connor, JT; Conwit, R; Elm, J; Fountain, NB; Holsti, M; Kapur, J; Lowenstein, D; Meinzer, C; Rogers, A; Shinnar, S; Silbergleit, R; Underwood, E | 1 |
| Charlier, C; Dubois, N; Gilson, M; Sqalli, G | 1 |
| Bleck, TP; Chamberlain, JM; Cloyd, JC; Cock, HR; Coles, LD; Conwit, RA; Elm, JJ; Fountain, NB; Kapur, J; Lowenstein, DH; Sathe, AG; Shinnar, S; Silbergleit, R | 1 |
| Limotai, C; Limotai, N; Mokklaew, J; Pattanasilp, B; Phayaph, N | 1 |
| Babl, FE; Hirsch, LJ; Josephson, SA; Wu, K | 1 |
| Hayashi, T; Noguchi, Y; Tachi, T; Takaoka, M; Teramachi, H | 1 |
| Drabik, M; Florek-Łuszczki, M; Głuszak, M; Jankiewicz, M; Kozińska, J; Plech, T; Plewa, Z; Wróblewska-Łuczka, P; Łuszczki, JJ | 1 |
| Babcock, L; Brundage, RC; Chamberlain, JM; Cloyd, JC; Cock, HR; Coles, LD; Elm, JJ; Fountain, NB; Ivaturi, V; Kapur, J; Lowenstein, DH; Mishra, U; Sathe, AG; Shinnar, S; Silbergleit, R | 1 |
| Agarwal, A; Arora, R; Ganeshan N, S; Gupta, YK; Kaleekal, T; Kumar, R; Sarangi, SC | 1 |
| Banach, M; Borowicz-Reutt, KK | 1 |
| Demir, O; Kaplan, YC | 1 |
| Brundage, RC; Chamberlain, JM; Cloyd, JC; Coles, LD; Elm, JJ; Ivaturi, V; Kapur, J; Sathe, AG; Silbergleit, R | 1 |
| Alunday, RL; Fletcher, ML; Nash, J; Sarangarm, P; Seifert, SA; Smolinske, SC; Warrick, BJ | 1 |
| Hira, D; Kakumoto, M; Okano, T; Shimokawa, K; Ueshima, S | 1 |
| Lattanzi, S; Zaccara, G | 1 |
| Donovan, PJ; Lander, CM; Madan, A; Risetto, T; Trenerry, H | 1 |
| Linnér, L; Loikas, D; Sundström, A; von Euler, M; Wettermark, B | 1 |
| Asadi-Pooya, AA; Mirzaei Damabi, N; Rostaminejad, M; Zeraatpisheh, Z | 1 |
| Aggarwal, A; Garg, R; Malhotra, R; Narang, M; Sharma, S | 1 |
| Chamberlain, J; Elm, J; Hill, CE; Kwok, M; Silbergleit, R; Terman, SW; Wabl, R | 1 |
| Baker, A; Cho, SJ; Park, E; Reid, AY | 1 |
| Demirci, H; Emmez, H; Gülbahar, Ö; Kuzucu, P; Özişik, P; Seymen, CM | 1 |
| Fagiolino, P; Vázquez, M | 1 |
| Dahale, AB; Lhamu, T; Loganathan, S; Mohan, V; Sadh, K | 1 |
| Ayar, A; Kurt, A; Salihoglu, AK | 1 |
| Aguglia, U; Bilo, L; Cianci, V; Di Carlo, C; Ferlazzo, E; Gasparini, S; Iannone, LF; Neri, S; Pascarella, A; Quaresima, P; Roberti, R; Rocca, M; Russo, E | 1 |
| Guan, S; Liu, J; Qian, F; Wang, Y; Wu, H; Yang, J | 1 |
| Bishop, C; Bonkovsky, HL; Ma, CD; Van Horn, CG; Wan, M | 1 |
| Cai, M; Guo, X; Han, Y; Lin, W; Yang, J; Zhong, R | 1 |
| Chamberlain, JM; Coralic, Z; Kapur, J; Olson, KR; Overbeek, D; Silbergleit, R | 1 |
| Agrawal, M; Dhurandhar, Y; Panda, SP | 1 |
| Urushidani, S | 1 |
| Allegaert, K; Yalcin, N | 1 |
| Kumar, A; Sharma, A | 1 |
| Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T | 1 |
| Aneja, S; Arya, R; Cunningham, J; Jain, P; Sharma, S | 1 |
| García-Peñas, JJ; González-Alguacil, E; Soto-Insuga, V | 1 |
| Banach, M; Borowicz-Reutt, K | 1 |
| Chan, HH; Chan, HY; Ip, BY; Ko, H; Lau, AY; Lau, LH; Leng, X; Leung, H; Leung, TW; Mok, VC; Soo, YO; Wong, GL; Yip, TC | 1 |
| Chen, L; Duan, Y; He, Y; Kang, L; Li, M; Li, T; Wen, Z | 1 |
| Cates, AL; Greene, SC; Weiss, S; Wyatt, K | 1 |
| Bernat, P; Kołodziejczyk, P; Tutka, P; Zagaja, M; Łuszczki, JJ | 1 |
| Liu, X; Peng, X | 1 |
| Czabanka, M; Kieslich, M; Merker, M; Purwien, L; Ronellenfitsch, MW; Rosenow, F; Schubert-Bast, S; Strzelczyk, A; Willems, LM | 1 |
165 review(s) available for phenytoin and valproic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Synthetic and therapeutic perspectives of nitrogen containing heterocycles as anti-convulsants.
Topics: Animals; Anticonvulsants; Heterocyclic Compounds; Humans; Molecular Structure; Seizures; Structure-Activity Relationship | 2020 |
Interactions with antiepileptic drugs.
Topics: Acetaminophen; Acetazolamide; Anti-Anxiety Agents; Anticoagulants; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Furosemide; Gonadal Steroid Hormones; Griseofulvin; Humans; Phenobarbital; Phenytoin; Primidone; Thiazines; Urea; Valproic Acid; Vitamin D | 1977 |
[Pharmacotherapy of epilepsy. II].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines; Valproic Acid | 1978 |
Psychotropic effect of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Mental Processes; Personality Inventory; Phenobarbital; Phenytoin; Psychiatric Status Rating Scales; Psychotropic Drugs; Thiazines; Valproic Acid | 1979 |
[Long-term anticonvulsant therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Epilepsy; Ethosuximide; Humans; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
Valproic acid. Review of a new antiepileptic drug.
Topics: Adolescent; Adult; Animals; Brain Chemistry; Drug Interactions; Electric Stimulation; Electroencephalography; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; gamma-Aminobutyric Acid; Half-Life; Humans; Intestinal Absorption; Mice; Phenobarbital; Phenytoin; Seizures; Sleep Stages; Valproic Acid | 1979 |
The medical treatment of epilepsy: initiation of drug therapy.
Topics: Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Bromides; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
[Laboratory controls in long-term treatment with anticonvulsive drugs (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Intestinal Absorption; Male; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid | 1977 |
[Valproic acid in the treatment of epilepsy with special emphasis on serum level determination (author's transl)].
Topics: Blood Platelets; Drug Interactions; Electroencephalography; Epilepsy; Fatigue; Half-Life; Humans; Phenobarbital; Phenylbutazone; Phenytoin; Protein Binding; Salicylates; Sulfadimethoxine; Valerates; Valproic Acid | 1978 |
[Antiepileptics during pregnancy and lactation. Pharmacokinetic data].
Topics: Anticonvulsants; Bromides; Carbamazepine; Clonazepam; Diazepam; Ethosuximide; Female; Fetus; Humans; Kinetics; Lactation; Maternal-Fetal Exchange; Nitrazepam; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1979 |
Pharmacological and biochemical studies in epileptic fowl.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Brain; Chickens; Disease Models, Animal; Ethosuximide; Female; Humans; Male; Mutation; Phenobarbital; Phenytoin; Photic Stimulation; Primidone; Seizures; Valproic Acid | 1979 |
Pharmacological prophylaxis in the kindling model of epilepsy.
Topics: Amygdala; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Atropine; Aziridines; Carbamazepine; Catecholamines; Cats; Cerebral Cortex; Chlorpromazine; Clorazepate Dipotassium; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy; Haplorhini; Hydroxydopamines; Phenobarbital; Phenytoin; Rats; Reserpine; Seizures; Valproic Acid | 1977 |
Clinical pharmacokinetics of anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Interactions; Ethosuximide; Female; Humans; Hydantoins; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Kidney Diseases; Kinetics; Liver Diseases; Milk; Molecular Biology; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1976 |
[Neurotoxicity of antiepileptic drugs].
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Ethosuximide; Humans; Male; Nervous System; Nervous System Diseases; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1992 |
Drugs used in the management of trigeminal neuralgia.
Topics: Anticonvulsants; Baclofen; Carbamazepine; Clonazepam; Humans; Oxcarbazepine; Phenytoin; Trigeminal Neuralgia; Valproic Acid | 1992 |
Metabolism of antiepileptic medication: newborn to elderly.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Half-Life; Humans; Infant, Newborn; Male; Middle Aged; Phenytoin; Valproic Acid | 1992 |
Rational use of antiepileptic drug levels.
Topics: Carbamazepine; Half-Life; Humans; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1992 |
Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy.
Topics: Anemia, Aplastic; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Monitoring; Epilepsy; Ethosuximide; Humans; Leukopenia; Phenytoin; Thrombocytopenia; Valproic Acid | 1991 |
Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significance.
Topics: Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Humans; Mephenytoin; Mephobarbital; Oxcarbazepine; Phenytoin; Primidone; Valproic Acid | 1991 |
Neurobehavioral effects of phenytoin, carbamazepine, and valproic acid: implications for use in traumatic brain injury.
Topics: Barbiturates; Brain Injuries; Carbamazepine; Cognition; Contraindications; Humans; Phenytoin; Valproic Acid | 1991 |
The newer antiepileptic drugs: carbamazepine and valproic acid.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Humans; Infant; Infant, Newborn; Phenytoin; Valproic Acid | 1991 |
Cognitive effects of antiepileptic drugs.
Topics: Anticonvulsants; Brain Diseases; Carbamazepine; Cognition; Drug Tolerance; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
[Aspects of antiepileptic drug therapy in children].
Topics: Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Combinations; Humans; Phenytoin; Valproic Acid | 1990 |
Antiepileptic drugs, cognitive function, and behavior in children: evidence from recent studies.
Topics: Adult; Age Factors; Anticonvulsants; Carbamazepine; Child; Cognition; Cognition Disorders; Epilepsy; Humans; Phenobarbital; Phenytoin; Psychological Tests; Research Design; Valproic Acid | 1990 |
Valproic acid prenatal exposure. Association with lipomyelomeningocele.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anticonvulsants; Cleft Palate; Female; Humans; Infant, Newborn; Male; Meningomyelocele; Phenytoin; Pregnancy; Valproic Acid | 1989 |
Adverse effects of antiepileptic drugs in children. The relevance of drug interaction.
Topics: Anticonvulsants; Carbamazepine; Child; Drug Interactions; Humans; Phenytoin; Valproic Acid | 1989 |
Poisoning by anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1989 |
[Problems of neurological drug therapy in pregnancy].
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Antiparkinson Agents; Carbamazepine; Chelating Agents; Female; Fetus; Haloperidol; Humans; Nervous System Diseases; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Trimethadione; Valproic Acid | 1989 |
Adverse neuropsychiatric effects of anticonvulsant drugs.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biogenic Amines; Carbamazepine; Cerebellar Ataxia; Dystonia; Ethosuximide; Folic Acid Deficiency; Hormones; Humans; Mental Disorders; Nervous System Diseases; Peripheral Nervous System Diseases; Phenytoin; Rats; Tremor; Valproic Acid | 1985 |
Anticonvulsant drugs: mechanisms of action.
Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Biomechanical Phenomena; Carbamazepine; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Phenytoin; Primidone; Succinimides; Synapses; Synaptic Transmission; Valproic Acid | 1986 |
[GABAergic theory of epilepsy].
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Benzodiazepines; Bicuculline; Brain; Dogs; Epilepsy; gamma-Aminobutyric Acid; Humans; Mice; Nerve Endings; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Receptors, GABA-A; Synapses; Valproic Acid | 1986 |
Posthypoxic action myoclonus: literature review update.
Topics: Adult; Clonazepam; Coma; Electroencephalography; Female; Functional Laterality; Heart Arrest; Humans; Hypoxia; Male; Middle Aged; Myocardial Infarction; Myoclonus; Phenytoin; Respiratory Distress Syndrome; Valproic Acid | 1986 |
Therapeutic drug monitoring in childhood.
Topics: Aminoglycosides; Anti-Bacterial Agents; Carbamazepine; Child; Chloramphenicol; Digoxin; Drug Interactions; Half-Life; Humans; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Saliva; Theophylline; Valproic Acid | 1986 |
Antidepressant drug therapy for bulimia: current status.
Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Feeding and Eating Disorders; Fenfluramine; Humans; Hyperphagia; Lithium; Lithium Carbonate; Methamphetamine; Monoamine Oxidase Inhibitors; Nomifensine; Phenytoin; Placebos; Propiophenones; Valproic Acid | 1986 |
Status epilepticus.
Topics: Adult; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Humans; Infant, Newborn; Lidocaine; Paraldehyde; Phenytoin; Status Epilepticus; Terminology as Topic; Valproic Acid | 1986 |
Carbamazepine drug interactions.
Topics: Carbamazepine; Cimetidine; Dextropropoxyphene; Drug Interactions; Erythromycin; Humans; Isoniazid; Lithium; Phenobarbital; Phenytoin; Primidone; Protein Binding; Troleandomycin; Valproic Acid; Warfarin | 1986 |
Antiepileptic drugs in adolescents.
Topics: Adaptation, Psychological; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Sports; Valproic Acid | 1987 |
Hepatic considerations in the use of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Hypersensitivity; Humans; Liver; Phenytoin; Risk Factors; Time Factors; Valproic Acid | 1987 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1987 |
[Therapy of brain-related minor seizures].
Topics: Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy, Absence; Humans; Phenytoin; Seizures; Valproic Acid | 1988 |
Effects of different classes of antiepileptic drugs on brain-stem pathways.
Topics: Animals; Anticonvulsants; Baclofen; Brain Stem; Carbamazepine; Disease Models, Animal; Electroshock; Ethosuximide; Phenytoin; Reticular Formation; Valproic Acid | 1985 |
Determination of antiepileptic drugs.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Chromatography, Liquid; Clonazepam; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Mephenytoin; Monitoring, Physiologic; Phenytoin; Primidone; Succinimides; Valproic Acid | 1985 |
Pharmacokinetics of anti-epileptic drugs in the dog: a review.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Clonazepam; Diazepam; Dog Diseases; Dogs; Epilepsy; Ethosuximide; Kinetics; Phenobarbital; Phenytoin; Primidone; Species Specificity; Trimethadione; Valproic Acid | 1985 |
Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats.
Topics: Animals; Antipyrine; Barbiturates; Biological Availability; Chlorpromazine; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Pentazocine; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Propranolol; Quinidine; Rats; Species Specificity; Tissue Distribution; Tolbutamide; Valproic Acid; Warfarin | 1985 |
Psychopharmacological aspects of antiepileptic treatment.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Electroencephalography; Epilepsy; Ethosuximide; Humans; Phenytoin; Psychological Tests; Psychometrics; Psychotropic Drugs; Research Design; Sampling Studies; Thiazines; Valproic Acid | 1980 |
[Advance and clinic of antiepileptic drugs (author's transl)].
Topics: Animals; Anticonvulsants; Benzodiazepines; Brain; Carbamazepine; Epilepsy; Humans; Ion Channels; Mice; Neurotransmitter Agents; Phenobarbital; Phenytoin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Valproic Acid | 1981 |
[Anticonvulsants and their side effects. II. Side effects].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Humans; Phenytoin; Primidone; Succinimides; Valproic Acid | 1980 |
Diagnosis and treatment of epilepsy.
Topics: Automatism; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Ethosuximide; Humans; Muscle Tonus; Phenobarbital; Phenytoin; Primidone; Telemetry; Valproic Acid | 1983 |
Therapy for status epilepticus.
Topics: Acetazolamide; Anesthesia; Anticonvulsants; Barbiturates; Chlormethiazole; Clonazepam; Diazepam; Ethosuximide; Humans; Lidocaine; Lorazepam; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus; Valproic Acid | 1983 |
Mental effects of antiepileptic medication: a review.
Topics: Adolescent; Adult; Anticonvulsants; Attention; Barbiturates; Brain Chemistry; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Folic Acid Deficiency; Humans; Mental Disorders; Mental Processes; Phenytoin; Psychomotor Performance; Psychoses, Substance-Induced; Serotonin; Valproic Acid | 1983 |
Treatment of mood disorders with antiepileptic medications: clinical and theoretical implications.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Clonazepam; Depressive Disorder; Diazepam; Double-Blind Method; Humans; Phenytoin; Valproic Acid | 1983 |
The clinical pharmacology of antiepileptic drugs.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Half-Life; Humans; Intestinal Absorption; Kidney; Kidney Diseases; Kinetics; Liver Diseases; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Tissue Distribution; Trimethadione; Valproic Acid | 1984 |
Clinical pharmacokinetics of sodium valproate, carbamazepine and phenytoin. Level-dose ration and interactions.
Topics: Carbamazepine; Drug Interactions; Epilepsy; Humans; Intestinal Absorption; Kinetics; Phenytoin; Valproic Acid | 1984 |
Pharmacokinetic interactions of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Drug Interactions; Humans; In Vitro Techniques; Intestinal Absorption; Kidney; Kinetics; Phenytoin; Protein Binding; Rats; Succinimides; Valproic Acid | 1984 |
Interactions between anticonvulsants and other commonly prescribed drugs.
Topics: Analgesics; Anti-Infective Agents; Anticoagulants; Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Drug Interactions; Humans; Intestinal Absorption; Kinetics; Phenobarbital; Phenytoin; Primidone; Protein Binding; Psychotropic Drugs; Succinimides; Sulfonamides; Tissue Distribution; Valproic Acid | 1984 |
Clinical pharmacokinetics of antiepileptic drugs in adults.
Topics: Adult; Aging; Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Disease; Ethosuximide; Female; Humans; Kinetics; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva; Valproic Acid | 1980 |
Anticonvulsant drugs in alcohol withdrawal: use of phenytoin, primidone, carbamazepine, valproic acid, and the sedative anticonvulsants.
Topics: Alcoholism; Anticonvulsants; Carbamazepine; Humans; Hypnotics and Sedatives; Phenytoin; Primidone; Status Epilepticus; Substance Withdrawal Syndrome; Valproic Acid | 1981 |
Pharmacological principles in the long-term treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Kinetics; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Succinimides; Valproic Acid | 1981 |
The epileptic mother and her child.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Fetal Blood; Humans; Infant, Newborn; Maternal-Fetal Exchange; Milk, Human; Phenobarbital; Phenytoin; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Protein Binding; Status Epilepticus; Valproic Acid | 1982 |
Antiepileptic therapeutic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
Valproic acid: interactions with phenytoin and phenobarbital.
Topics: Binding, Competitive; Drug Interactions; Half-Life; Humans; Kinetics; Phenobarbital; Phenytoin; Protein Binding; Seizures; Valproic Acid | 1982 |
Use of antiepileptic drugs in the presence of liver and kidney diseases: a review.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Half-Life; Humans; Kidney Diseases; Kinetics; Liver Diseases; Phenobarbital; Phenytoin; Valproic Acid | 1982 |
Drug interactions with valproic acid.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Fatty Acids, Nonesterified; Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Salicylates; Valproic Acid | 1982 |
Status epilepticus.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Brain; Electroencephalography; Epilepsy; Female; Humans; Middle Aged; Phenytoin; Prognosis; Valproic Acid | 1995 |
Anticonvulsant drugs for management of pain: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diabetic Neuropathies; Humans; Pain; Phenytoin; Treatment Outcome; Trigeminal Neuralgia; Valproic Acid | 1995 |
Pregnancy, teratogenesis, and epilepsy.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Epilepsy; Female; Fetus; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 1994 |
Standard approach to antiepileptic drug treatment in the United Kingdom.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Prognosis; United Kingdom; Valproic Acid | 1994 |
Pharmacologic intervention and treatment of childhood seizure disorders: relative efficacy and safety of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Child; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Humans; Mice; Phenobarbital; Phenytoin; Treatment Outcome; Valproic Acid | 1994 |
Valproate-induced coma: case report and literature review.
Topics: Ammonia; Coma; Epilepsy, Complex Partial; Female; Humans; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1993 |
Drug interaction profile of topiramate.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Male; Phenytoin; Topiramate; Treatment Outcome; Valproic Acid | 1996 |
Antiepileptic drug mechanisms of action.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Calcium Channels; Carbamazepine; Central Nervous System; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Phenytoin; Rats; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium Channels; Triazines; Trimethadione; Valproic Acid; Vigabatrin | 1995 |
Clinically significant pharmacokinetic drug interactions with carbamazepine. An update.
Topics: Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Carbamazepine; Drug Interactions; Ethosuximide; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Valproic Acid | 1996 |
Erythrocytes and the transport of drugs and endogenous compounds.
Topics: Animals; Biological Transport; Blood Proteins; Erythrocytes; Humans; Hydrocortisone; Phenytoin; Valproic Acid; Water | 1996 |
Antiepileptic drugs--current use.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Phenytoin; Valproic Acid | 1996 |
[The diagnosis and treatment of partial epilepsy in childhood and adolescence].
Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Epilepsy, Frontal Lobe; Epilepsy, Temporal Lobe; Humans; Infant; Phenytoin; Sleep, REM; Valproic Acid | 1996 |
Established antiepileptic drugs.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Epilepsy; Humans; Phenytoin; Succinimides; Valproic Acid | 1996 |
New drug therapy for acute seizure management.
Topics: Acute Disease; Anticonvulsants; Child; Diazepam; Epilepsy; Humans; Phenytoin; Prodrugs; Seizures; Valproic Acid | 1997 |
Pharmacologic and dietary therapies in epilepsy: conventional treatments and recent advances.
Topics: Acetates; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketone Bodies; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin | 1997 |
Pharmacokinetic interactions with felbamate. In vitro-in vivo correlation.
Topics: Anticonvulsants; Area Under Curve; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Epilepsy; Felbamate; Humans; In Vitro Techniques; Isoenzymes; Neuroprotective Agents; Phenylcarbamates; Phenytoin; Propylene Glycols; Valproic Acid | 1997 |
A meta-analytic review of the preventive treatment of recurrences of febrile seizures.
Topics: Anticonvulsants; Chi-Square Distribution; Child; Diazepam; Drug Administration Schedule; Fever; Humans; Odds Ratio; Phenobarbital; Phenytoin; Pyridoxine; Randomized Controlled Trials as Topic; Recurrence; Risk Assessment; Seizures, Febrile; Valproic Acid | 1997 |
Advances in the medical treatment of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin | 1998 |
Antiepileptic drug review: part 1.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Drug Interactions; Half-Life; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1998 |
Anticonvulsant therapy in small animals.
Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid | 1998 |
Standards of laboratory practice: antiepileptic drug monitoring. National Academy of Clinical Biochemistry.
Topics: Anticonvulsants; Blood Specimen Collection; Carbamazepine; Drug Interactions; Drug Monitoring; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Valproic Acid | 1998 |
A mechanistic approach to antiepileptic drug interactions.
Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 1998 |
Features and management of poisoning with modern drugs used to treat epilepsy.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Phenytoin; Valproic Acid | 1998 |
[Neurotoxicity of anticonvulsants].
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenytoin; Primidone; Valproic Acid | 1999 |
Monostars: an aid to choosing an antiepileptic drug as monotherapy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Practice Patterns, Physicians'; Triazines; Valproic Acid; Vigabatrin | 1999 |
Is generic prescribing acceptable in epilepsy?
Topics: Anticonvulsants; Area Under Curve; Biological Availability; Carbamazepine; Chemistry, Pharmaceutical; Drugs, Generic; Epilepsy; Humans; Phenytoin; Therapeutic Equivalency; Valproic Acid | 2000 |
Therapeutic safety monitoring: what to look for and when to look for it.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2000 |
New antiepileptic drugs and preparations.
Topics: Acetates; Administration, Rectal; Age Factors; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diazepam; Drug Overdose; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines; Valproic Acid | 2000 |
Status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Midazolam; Phenobarbital; Phenytoin; Propofol; Status Epilepticus; Valproic Acid | 2001 |
Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials.
Topics: Anticonvulsants; Brain Diseases; Brain Injuries; Carbamazepine; Controlled Clinical Trials as Topic; Diazepam; Epilepsy; Humans; Lorazepam; Models, Statistical; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Risk; Seizures; Treatment Outcome; Valproic Acid | 2001 |
Treatment of epilepsy in 3 specialized populations.
Topics: Age Factors; Aged; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Epilepsy; Female; Humans; Outcome Assessment, Health Care; Phenytoin; Polypharmacy; Pregnancy; Teratogens; Valproic Acid | 2001 |
Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures.
Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy, Generalized; Humans; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Valproic Acid | 2001 |
Anticonvulsants for neuropathic pain and detoxification.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clonazepam; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Inactivation, Metabolic; Lamotrigine; Neuralgia; Phenytoin; Substance Withdrawal Syndrome; Triazines; Valproic Acid | 1998 |
The current state of treatment of status epilepticus.
Topics: Animals; Anticonvulsants; Benzodiazepines; Brain; Electroencephalography; Female; GABA Modulators; Humans; Midazolam; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Status Epilepticus; Treatment Outcome; Valproic Acid | 2002 |
Teratogen-induced limb defects.
Topics: Chorionic Villi Sampling; Female; Humans; Limb Deformities, Congenital; Male; Misoprostol; Phenytoin; Pregnancy; Pregnancy in Diabetics; Substance-Related Disorders; Teratogens; Thalidomide; Valproic Acid; Warfarin | 2002 |
New management strategies in the treatment of status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Emergency Medical Services; Humans; Phenobarbital; Phenytoin; Status Epilepticus; United States; Valproic Acid | 2003 |
The management of idiopathic olfactory hallucinations: a study of two patients.
Topics: Adult; Anticonvulsants; Female; Hallucinations; Humans; Middle Aged; Phenytoin; Retrospective Studies; Valproic Acid | 2003 |
[Clinical guidelines for treatment of epilepsy in children].
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Cosyntropin; Electroencephalography; Epilepsy; Frontal Lobe; Humans; Isoxazoles; Life Style; Magnetic Resonance Imaging; Phenytoin; Practice Guidelines as Topic; Temporal Lobe; Valproic Acid; Zonisamide | 2004 |
Cancer risk in people with epilepsy: the role of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Neoplasms; Phenobarbital; Phenytoin; Rats; Risk Factors; Valproic Acid | 2005 |
Seizure prophylaxis in patients with brain tumors: a meta-analysis.
Topics: Anticonvulsants; Brain Neoplasms; Comorbidity; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Incidence; Male; Odds Ratio; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Risk Assessment; Seizures; Treatment Failure; Valproic Acid | 2004 |
Mechanisms regulating toxicant disposition to the embryo during early pregnancy: an interspecies comparison.
Topics: Animals; Biological Transport; Carbamazepine; Embryonic Development; Female; Humans; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Placenta; Pregnancy; Rabbits; Rats; Salicylic Acid; Species Specificity; Teratogens; Toxicity Tests; Tretinoin; Valproic Acid; Yolk Sac | 2004 |
[Epilepsy and male sexual dysfunction: etiology, diagnosis and therapy].
Topics: Androgens; Anticonvulsants; Bromocriptine; Carbamazepine; Cognition; Enzyme Induction; Epilepsy; Gonadal Steroid Hormones; Humans; Lamotrigine; Liver; Male; Oxcarbazepine; Phenytoin; Sexual Dysfunctions, Psychological; Testosterone; Triazines; Valproic Acid | 2006 |
[Anticonvulsants treatment of psychiatric disorder in elderly patients].
Topics: Aged; Anticonvulsants; Anxiety Disorders; Bipolar Disorder; Carbamazepine; Epilepsy; Humans; Mental Disorders; Mood Disorders; Phenytoin; Psychotic Disorders; Valproic Acid | 2006 |
Therapeutic monitoring of antiepileptic drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 2007 |
Pharmacokinetics of antiepileptic drugs in elderly nursing home residents.
Topics: Aged; Anticonvulsants; Carbamazepine; Humans; Nursing Homes; Phenobarbital; Phenytoin; Valproic Acid | 2007 |
[Anticonvulsants in the treatment of bipolar disorder].
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Lamotrigine; Phenytoin; Treatment Outcome; Triazines; Valproic Acid | 2007 |
[Neuromuscular disorders caused by adverse effects of antiepileptics].
Topics: Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Neuromuscular Diseases; Phenobarbital; Phenytoin; Topiramate; Valproic Acid; Zonisamide | 2007 |
Antiepileptic drugs as human teratogens.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2008 |
Clinical pharmacology of parenteral use of antiepileptic drugs.
Topics: Anticonvulsants; Epilepsy; Humans; Infusions, Intravenous; Injections, Intravenous; Levetiracetam; Pharmaceutical Vehicles; Phenytoin; Piracetam; Solubility; Valproic Acid | 2007 |
[Caffeine and antiepileptic drugs: experimental and clinical data].
Topics: Animals; Anticonvulsants; Caffeine; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Humans; Lamotrigine; Mice; Nipecotic Acids; Phenobarbital; Phenytoin; Seizures; Tiagabine; Triazines; Valproic Acid | 2007 |
Antiepileptic drugs and thyroid function.
Topics: Anticonvulsants; Carbamazepine; Humans; Phenytoin; Thyroid Gland; Thyroid Hormones; Valproic Acid | 2008 |
[Drugs for status epilepticus treatment].
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Fructose; Humans; Hypnotics and Sedatives; Levetiracetam; Phenytoin; Piracetam; Propofol; Status Epilepticus; Topiramate; Valproic Acid | 2009 |
Traditional Chinese medicine for epilepsy.
Topics: Anticonvulsants; Drugs, Chinese Herbal; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Medicine, Chinese Traditional; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Valproic Acid | 2009 |
What is the relative value of the standard anticonvulsants: Phenytoin and fosphenytoin, phenobarbital, valproate, and levetiracetam?
Topics: Anticonvulsants; Benzodiazepines; Humans; Levetiracetam; Phenobarbital; Phenytoin; Piracetam; Prodrugs; Status Epilepticus; Treatment Outcome; Valproic Acid | 2009 |
New antiepileptic drugs: molecular targets.
Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Carbamazepine; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Monitoring; Electroshock; Epilepsy; Ethosuximide; gamma-Aminobutyric Acid; Humans; Molecular Structure; Neurotransmitter Transport Proteins; Phenytoin; Randomized Controlled Trials as Topic; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship; Synaptic Transmission; Treatment Outcome; Valproic Acid | 2009 |
Epilepsy (generalised).
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Epilepsy, Generalized; Humans; Incidence; Phenytoin; Remission Induction; Valproic Acid | 2010 |
Side effects of phenobarbital in epilepsy: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Child; Cognition Disorders; Cohort Studies; Cross-Over Studies; Data Collection; Data Interpretation, Statistical; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Randomized Controlled Trials as Topic; Research; Research Design; Treatment Outcome; Valproic Acid | 2011 |
Management of acute seizure and status epilepticus in pediatric emergency.
Topics: Anesthesia, Intravenous; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Combined Modality Therapy; Cross-Sectional Studies; Developing Countries; Dose-Response Relationship, Drug; Emergency Service, Hospital; Epilepsy; Humans; India; Infant; Infusions, Intravenous; Intensive Care Units, Pediatric; Levetiracetam; Lorazepam; Phenytoin; Piracetam; Seizures; Status Epilepticus; Thiopental; Valproic Acid | 2012 |
IV Valproate in generalized convulsive status epilepticus: a systematic review.
Topics: Administration, Intravenous; Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Female; Humans; Male; Middle Aged; Phenytoin; Randomized Controlled Trials as Topic; Status Epilepticus; Valproic Acid; Young Adult | 2012 |
A systematic review of randomized controlled trials on the theraputic effect of intravenous sodium valproate in status epilepticus.
Topics: Anticonvulsants; Diazepam; Humans; Injections, Intravenous; Levetiracetam; Phenytoin; Piracetam; Randomized Controlled Trials as Topic; Status Epilepticus; Valproic Acid | 2012 |
Epilepsy (generalised).
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Epilepsy, Generalized; Humans; Incidence; Phenytoin; Remission Induction; Valproic Acid | 2012 |
Efficacy and safety of innovator versus generic drugs in patients with epilepsy: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drugs, Generic; Endpoint Determination; Epilepsy; Hospitalization; Humans; Length of Stay; Meta-Analysis as Topic; Phenytoin; Randomized Controlled Trials as Topic; Treatment Outcome; Valproic Acid | 2012 |
Impact of particular antiepileptic drugs on the survival of patients with glioblastoma multiforme.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Brain Neoplasms; Carbamazepine; Cohort Studies; Female; Glioblastoma; Histone Deacetylase Inhibitors; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Phenytoin; Survival Rate; Treatment Outcome; Valproic Acid; Young Adult | 2013 |
Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalised onset tonic-clonic seizures.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; Induction Chemotherapy; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Recurrence; Seizures; Time Factors; Valproic Acid | 2013 |
Antiepileptic drugs as prophylaxis for post-craniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2013 |
Seizures and intracranial hemorrhage.
Topics: Anticonvulsants; Carbamazepine; Congenital Abnormalities; Eclampsia; Epilepsy; Female; Folic Acid; Heparin; Humans; Infant, Newborn; Intracranial Hemorrhages; Lamotrigine; Monitoring, Physiologic; North America; Phenobarbital; Phenytoin; Pregnancy; Risk Factors; Seizures; Subarachnoid Hemorrhage; Triazines; Valproic Acid; Vitamin K | 2013 |
Phenytoin versus valproate monotherapy for partial onset seizures and generalised onset tonic-clonic seizures.
Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Valproic Acid | 2013 |
Analysis of seizure risk factors after allogeneic hematopoietic stem cell transplantation: a 8 case report and literature review.
Topics: Adolescent; Adult; Anticonvulsants; Fatal Outcome; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Male; Phenytoin; Retrospective Studies; Seizures; Transplantation, Homologous; Treatment Outcome; Valproic Acid; Young Adult | 2013 |
WITHDRAWN: Traditional Chinese medicine for epilepsy.
Topics: Anticonvulsants; Drugs, Chinese Herbal; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Medicine, Chinese Traditional; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Valproic Acid | 2014 |
Acupuncture for epilepsy.
Topics: Acupuncture Therapy; Anticonvulsants; Child; Combined Modality Therapy; Drugs, Chinese Herbal; Epilepsy, Generalized; Humans; Phenytoin; Randomized Controlled Trials as Topic; Treatment Outcome; Valproic Acid | 2014 |
Developmental neurotoxicity and anticonvulsant drugs: a possible link.
Topics: Animals; Anticonvulsants; Breast Feeding; Carbamazepine; Cognition Disorders; Developmental Disabilities; Female; Humans; Lamotrigine; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Triazines; Valproic Acid | 2014 |
Antiepileptic drugs: Energy-consuming processes governing drug disposition.
Topics: Anticonvulsants; Biological Transport; Carbamazepine; Cardiac Output; Energy Metabolism; Humans; Intestinal Absorption; Kidney; Liver; Membrane Transport Modulators; Phenytoin; Valproic Acid | 2014 |
Antiepileptic drugs as prophylaxis for post-craniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2015 |
Pharmacological treatments for preventing epilepsy following traumatic head injury.
Topics: Adult; Anticonvulsants; Carbamazepine; Cause of Death; Child; Craniocerebral Trauma; Epilepsy; Humans; Levetiracetam; Magnesium Sulfate; Neuroprotective Agents; Phenytoin; Piracetam; Randomized Controlled Trials as Topic; Valproic Acid | 2015 |
Efficacy and safety of prophylactic levetiracetam in supratentorial brain tumour surgery: a systematic review and meta-analysis.
Topics: Anticonvulsants; Craniotomy; Humans; Levetiracetam; Perioperative Care; Phenytoin; Piracetam; Seizures; Supratentorial Neoplasms; Valproic Acid | 2016 |
[Preconceptional and perinatal challenges of pregnancy in women with epilepsy].
Topics: Adult; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Parturition; Perinatal Care; Phenobarbital; Phenytoin; Piracetam; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Teratogens; Triazines; Valproic Acid | 2016 |
Phenytoin versus valproate monotherapy for partial onset seizures and generalised onset tonic-clonic seizures: an individual participant data review.
Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Valproic Acid | 2016 |
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy.
Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide | 2016 |
Direct and indirect comparison meta-analysis of levetiracetam versus phenytoin or valproate for convulsive status epilepticus.
Topics: Anticonvulsants; Humans; Levetiracetam; Phenytoin; Piracetam; Status Epilepticus; Valproic Acid | 2016 |
Quetiapine-induced absence seizures in a dementia patient.
Topics: Aged; Anticonvulsants; Antipsychotic Agents; Dementia; Epilepsy, Absence; Female; Follow-Up Studies; Humans; Phenytoin; Quetiapine Fumarate; Rare Diseases; Risk Assessment; Severity of Illness Index; Treatment Outcome; Valproic Acid | 2016 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Essential Oils as an Alternative to Pyrethroids' Resistance against Anopheles Species Complex Giles (Diptera: Culicidae).
Topics: Animals; Anopheles; Caco-2 Cells; Carbamazepine; Diptera; Hep G2 Cells; Humans; Lamotrigine; Levetiracetam; Oils, Volatile; Phenytoin; Piracetam; Pyrethrins; Triazines; Valproic Acid | 2017 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Levetiracetam; Phenobarbital; Phenytoin; Piracetam; Postoperative Complications; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2018 |
[Medicaments and oral healthcare. Proliferation of the gingiva].
Topics: Anticonvulsants; Carbamazepine; Cell Proliferation; Ethosuximide; Gingiva; Humans; Netherlands; Oral Hygiene; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 2018 |
Sodium valproate versus phenytoin monotherapy for epilepsy: an individual participant data review.
Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy, Generalized; Humans; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Treatment Outcome; Valproic Acid | 2018 |
Choice of therapeutic anti-seizure medication in patients with brain tumour.
Topics: Anticonvulsants; Brain Neoplasms; Drug Therapy, Combination; Epilepsy; Gabapentin; Glioma; Humans; Lamotrigine; Levetiracetam; Neoplasm Grading; Phenytoin; Survival Rate; Topiramate; Valproic Acid; Zonisamide | 2019 |
Meta-analysis and cost-effectiveness of second-line antiepileptic drugs for status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Cost-Benefit Analysis; Decision Support Techniques; Humans; Lacosamide; Levetiracetam; Phenobarbital; Phenytoin; Status Epilepticus; Treatment Failure; Valproic Acid | 2019 |
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Levetiracetam; Phenobarbital; Phenytoin; Piracetam; Postoperative Complications; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2020 |
Use of Phenytoin, Phenobarbital Carbamazepine, Levetiracetam Lamotrigine and Valproate in Pregnancy and Breastfeeding: Risk of Major Malformations, Dose-dependency, Monotherapy vs Polytherapy, Pharmacokinetics and Clinical Implications.
Topics: Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2021 |
A systematic review of second line therapies in toxic seizures.
Topics: Anticonvulsants; Female; Humans; Male; Phenytoin; Seizures; Valproic Acid | 2021 |
A review of pharmacokinetic drug interactions between antimicrobial and antiseizure medications in children.
Topics: Anti-Bacterial Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Drug Interactions; Humans; Pharmaceutical Preparations; Phenytoin; Valproic Acid; Voriconazole | 2021 |
Cosmetic adverse effects of antiseizure medications; A systematic review.
Topics: Animals; Anticonvulsants; Epilepsy; Humans; Phenytoin; Quality of Life; Valproic Acid | 2021 |
The role of efflux transporters and metabolizing enzymes in brain and peripheral organs to explain drug-resistant epilepsy.
Topics: Brain; Drug Resistant Epilepsy; Humans; Membrane Transport Proteins; Phenytoin; Valproic Acid | 2022 |
Status epilepticus in pregnancy: a literature review and a protocol proposal.
Topics: Anticonvulsants; Female; Humans; Levetiracetam; Phenytoin; Pregnancy; Review Literature as Topic; Status Epilepticus; Valproic Acid | 2022 |
Side effects of long-term oral anti-seizure drugs on thyroid hormones in patients with epilepsy: a systematic review and network meta-analysis.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Topiramate; Valproic Acid | 2022 |
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches.
Topics: Anticonvulsants; Carbamazepine; Dementia; Epilepsy; Felbamate; Gabapentin; Humans; Inflammasomes; Lamotrigine; Mitophagy; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxcarbazepine; Parkinson Disease; Phenytoin; Seizures; Topiramate; Triazines; Ubiquitin-Protein Ligases; Valproic Acid | 2022 |
COVID-19 and antiepileptic drugs: an approach to guide practices when nirmatrelvir/ritonavir is co-prescribed.
Topics: Anticonvulsants; Carbamazepine; Clobazam; COVID-19 Drug Treatment; Cytochrome P-450 CYP3A Inducers; Drug Interactions; Humans; Oxcarbazepine; Pentobarbital; Phenobarbital; Phenytoin; Ritonavir; Valproic Acid | 2022 |
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide | 2022 |
Treatment of benzodiazepine-resistant status epilepticus: Systematic review and network meta-analyses.
Topics: Adult; Anticonvulsants; Benzodiazepines; Child; Drug Resistance; Humans; Levetiracetam; Network Meta-Analysis; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Status Epilepticus; Treatment Outcome; Valproic Acid | 2022 |
[Paediatric status epilepticus].
Topics: Adult; Anesthetics; Anticonvulsants; Benzodiazepines; Child; Epilepsy; Humans; Ketamine; Lacosamide; Levetiracetam; Lidocaine; Phenobarbital; Phenytoin; Propofol; Seizures; Status Epilepticus; Topiramate; Valproic Acid | 2022 |
83 trial(s) available for phenytoin and valproic acid
| Article | Year |
|---|---|
[Experiences with sodium 2-propyl valerate (Depakine) in the treatment of epilepsy].
Topics: Adolescent; Adult; Aged; Carbamazepine; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy; Female; Humans; Hydrocephalus; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Spasms, Infantile; Valerates; Valproic Acid | 1977 |
Valproate sodium: a controlled clinical trial including monitoring of drug levels.
Topics: Adult; Child; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Placebos; Valerates; Valproic Acid | 1977 |
Valproic acid in epilepsy: clinical and pharmacological effects.
Topics: Adult; Binding, Competitive; Biological Availability; Blood Proteins; Clinical Trials as Topic; Drug Interactions; Epilepsy; Female; Humans; Male; Phenytoin; Protein Binding; Valerates; Valproic Acid | 1978 |
Sodium valproate, serum level and clinical effect in epilepsy: a controlled study.
Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Dimethadione; Dose-Response Relationship, Drug; Drug Evaluation; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1979 |
Modification of phenytoin clearance by valproic acid in normal subjects.
Topics: Adult; Female; Half-Life; Humans; Injections, Intravenous; Kinetics; Male; Phenytoin; Time Factors; Valproic Acid | 1979 |
Controlled trial of sodium valproate in severe epilepsy.
Topics: Adult; Clinical Trials as Topic; Drug Evaluation; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Placebos; Valerates; Valproic Acid | 1975 |
Comparison of sodium valproate and phenytoin as single drug treatment in generalised and partial epilepsy.
Topics: Adolescent; Adult; Child; Epilepsies, Partial; Epilepsy, Generalized; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1991 |
Cognitive impairment in new cases of epilepsy randomly assigned to carbamazepine, phenytoin and sodium valproate.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cognition; Epilepsy; Humans; Intelligence Tests; Phenytoin; Random Allocation; Valproic Acid | 1991 |
Discontinuation of antiepileptic drugs in children who have outgrown epilepsy: effects on cognitive function.
Topics: Adolescent; Anticonvulsants; Attention; Carbamazepine; Child; Cognition; Epilepsy; Ethosuximide; Humans; Memory, Short-Term; Phenytoin; Psychomotor Performance; Reaction Time; Valproic Acid | 1990 |
[Clinical and experimental control of optimal therapy in epilepsy].
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Neurocognitive Disorders; Neuropsychological Tests; Phenytoin; Primidone; Substance-Related Disorders; Valproic Acid | 1990 |
Antidepressant drug therapy for bulimia: current status.
Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Feeding and Eating Disorders; Fenfluramine; Humans; Hyperphagia; Lithium; Lithium Carbonate; Methamphetamine; Monoamine Oxidase Inhibitors; Nomifensine; Phenytoin; Placebos; Propiophenones; Valproic Acid | 1986 |
Serum levels of sodium valproate, phenytoin and carbamazepine and seizure control in epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Prospective Studies; Valproic Acid | 1986 |
A comparative study of progabide, valproate, and placebo as add-on therapy in patients with refractory epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Patient Compliance; Phenytoin; Valproic Acid | 1986 |
Withdrawal of anticonvulsant drugs in patients free of seizures for two years. A prospective study.
Topics: Adult; Analysis of Variance; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Phenytoin; Prognosis; Prospective Studies; Random Allocation; Recurrence; Substance Withdrawal Syndrome; Time Factors; Valproic Acid | 1988 |
Valproic acid in Isaacs-Mertens syndrome.
Topics: Adolescent; Adult; Carbamazepine; Clinical Trials as Topic; Electromyography; Humans; Middle Aged; Muscles; Neuromuscular Diseases; Phenytoin; Sural Nerve; Syndrome; Valproic Acid | 1987 |
Withdrawal symptoms from phenytoin, carbamazepine and sodium valproate.
Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Prospective Studies; Substance Withdrawal Syndrome; Valproic Acid | 1988 |
Which drug for the adult epileptic patient: phenytoin or valproate?
Topics: Adolescent; Adult; Aged; Body Weight; Clinical Trials as Topic; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1985 |
[Efficient serum concentrations after single doses of antiepileptic drugs: concept of loading-dose].
Topics: Absorption; Administration, Oral; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsy; Humans; Kinetics; Male; Phenytoin; Valproic Acid | 1985 |
A prospective study between carbamazepine, phenytoin and sodium valproate as monotherapy in previously untreated and recently diagnosed patients with epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Evoked Potentials; Female; Humans; Kinetics; Male; Middle Aged; Phenytoin; Prospective Studies; Valproic Acid | 1985 |
Serum concentrations and enzyme induction in epileptic children treated with phenytoin and valproate.
Topics: Child; Enzyme Induction; Epilepsy; gamma-Glutamyltransferase; Humans; Phenytoin; Valproic Acid | 1982 |
[Anti-epileptic agents during pregnancy. A prospective study on the course of pregnancy, malformations and child development].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Akathisia, Drug-Induced; Anencephaly; Anticonvulsants; Craniofacial Dysostosis; Epilepsy; Female; Fetal Growth Retardation; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Primidone; Substance Withdrawal Syndrome; Uterine Cervical Incompetence; Valproic Acid | 1983 |
Comparison of valproic acid and phenytoin in newly diagnosed tonic-clonic seizures.
Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsies, Myoclonic; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1983 |
Treatment of mood disorders with antiepileptic medications: clinical and theoretical implications.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Clonazepam; Depressive Disorder; Diazepam; Double-Blind Method; Humans; Phenytoin; Valproic Acid | 1983 |
Controlled and comparative trials of valproate performed in Europe and Asia.
Topics: Adolescent; Adult; Asia; Carbamazepine; Child; Clinical Trials as Topic; Epilepsy; Europe; Humans; Phenobarbital; Phenytoin; Seizures, Febrile; Valproic Acid | 1984 |
Controlled and comparative trials with valproate: United States.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Middle Aged; Phenytoin; Spasms, Infantile; United States; Valproic Acid | 1984 |
A randomised trial of strategies to improve patient compliance with anticonvulsant therapy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Counseling; Drug Packaging; Epilepsy; Female; Humans; Male; Patient Compliance; Phenytoin; Random Allocation; Valproic Acid | 1984 |
Selective response to the anticonvulsant carbamazepine in manic-depressive illness: a case study.
Topics: Bipolar Disorder; Carbamazepine; Dose-Response Relationship, Drug; Female; Humans; Lithium; Middle Aged; Phenytoin; Valproic Acid | 1984 |
Role of combination of valproic acid with diphenylhydantoin and carbamazepine in the management of intractable seizures.
Topics: Adolescent; Adult; Carbamazepine; Clinical Trials as Topic; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1984 |
Comparison of sodium valproate and phenytoin as single drug treatment in epilepsy.
Topics: Adolescent; Adult; Aged; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Pregnancy; Time Factors; Valproic Acid | 1981 |
Intravenous valproate: effects on plasma and saliva phenytoin levels.
Topics: Adolescent; Adult; Blood Proteins; Drug Interactions; Female; Humans; Injections, Intravenous; Male; Phenytoin; Saliva; Valproic Acid | 1981 |
A comparison of phenytoin and valproate in previously untreated adult epileptic patients.
Topics: Adolescent; Adult; Age Factors; Aged; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Humans; Middle Aged; Patient Compliance; Phenytoin; Random Allocation; Valproic Acid | 1982 |
Anticonvulsant drugs for management of pain: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diabetic Neuropathies; Humans; Pain; Phenytoin; Treatment Outcome; Trigeminal Neuralgia; Valproic Acid | 1995 |
Interaction between valproate formulation and phenytoin concentrations.
Topics: Adolescent; Adult; Child; Circadian Rhythm; Delayed-Action Preparations; Drug Interactions; Female; Humans; Male; Phenytoin; Retrospective Studies; Valproic Acid | 1995 |
Comparative cognitive effects of phenobarbital, phenytoin, and valproate in healthy adults.
Topics: Adult; Cognition; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Phenobarbital; Phenytoin; Reference Values; Valproic Acid | 1995 |
Phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed adult epilepsy: a randomised comparative monotherapy trial.
Topics: Adolescent; Adult; Aged; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prospective Studies; Valproic Acid | 1995 |
Withdrawal of antiepileptic medication in children. Correlation of cognitive function and plasma concentration--the multicentre 'Holmfrid' study.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Cognition; Humans; Phenytoin; Substance Withdrawal Syndrome; Valproic Acid | 1994 |
Renal tubular dysfunction following treatment with anti-epileptic drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross-Sectional Studies; Epilepsy; Ethosuximide; Humans; Infant; Kidney Function Tests; Kidney Tubules; Phenytoin; Valproic Acid | 1994 |
A double-blind, placebo-controlled interaction study between oxcarbazepine and carbamazepine, sodium valproate and phenytoin in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Double-Blind Method; Drug Interactions; Epilepsy; Female; Half-Life; Humans; Male; Middle Aged; Oxcarbazepine; Phenytoin; Valproic Acid | 1994 |
Developmental and therapeutic pharmacology of antiepileptic drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electroencephalography; Epilepsy; Female; Half-Life; Humans; Infant; Isoxazoles; Male; Phenytoin; Prospective Studies; Valproic Acid; Zonisamide | 1993 |
Withdrawal of antiepileptic medication in children--effects on cognitive function: The Multicenter Holmfrid Study.
Topics: Adolescent; Carbamazepine; Child; Cognition; Cognition Disorders; Epilepsy; Female; Follow-Up Studies; Humans; Male; Memory Disorders; Neuropsychological Tests; Phenytoin; Valproic Acid | 1993 |
Psychiatric aspects of epilepsy in childhood treated with carbamazepine, phenytoin or sodium valproate: a random trial.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Follow-Up Studies; Humans; Male; Mental Disorders; Mothers; Phenytoin; Psychological Tests; Valproic Acid | 1993 |
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo.
Topics: Administration, Oral; Adult; Antipyrine; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Ethosuximide; Humans; Liver; Lorazepam; Male; Oxidoreductases, N-Demethylating; Phenobarbital; Phenytoin; Quinidine; Rifampin; Smoking; Theophylline; Valproic Acid | 1993 |
A comparison of the OPUS and TDx analysers for antiepileptic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Female; Fluorescence Polarization Immunoassay; Humans; Immunoassay; Male; Phenobarbital; Phenytoin; Regression Analysis; Reproducibility of Results; Valproic Acid | 1995 |
Randomised comparative monotherapy trial of phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed childhood epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Prospective Studies; Treatment Outcome; Valproic Acid | 1996 |
Assessment of drowsiness in epilepsy patients receiving chronic antiepileptic drug therapy.
Topics: Adult; Age Factors; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Psychiatric Status Rating Scales; Psychological Tests; Sleep Stages; Valproic Acid; Wakefulness | 1996 |
The effects of antiepileptic drugs on cognition in normal volunteers.
Topics: Adult; Anticonvulsants; Carbamazepine; Cognition; Cross-Over Studies; Double-Blind Method; Humans; Isoxazoles; Phenytoin; Valproic Acid; Wechsler Scales; Zonisamide | 1996 |
Antiepileptic drug treatment in pregnancy: drug side effects in the neonate and neurological outcome.
Topics: Anticonvulsants; Child; Drug Monitoring; Epilepsy; Female; Follow-Up Studies; Humans; Nervous System Diseases; Neurologic Examination; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Primidone; Valproic Acid | 1996 |
Serum concentrations of lamotrigine in epileptic patients: the influence of dose and comedication.
Topics: Adult; Age Factors; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Triazines; Valproic Acid | 1996 |
Comparison of phenobarbitone, phenytoin with sodium valproate: randomized, double-blind study.
Topics: Child; Child, Preschool; Epilepsy, Tonic-Clonic; Female; Humans; Phenobarbital; Phenytoin; Recurrence; Valproic Acid | 1996 |
Outcome evaluation of gabapentin as add-on therapy for partial seizures. "NEON" Study Investigators Group. Neurontin Evaluation of Outcomes in Neurological Practice.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurologic Examination; Phenobarbital; Phenytoin; Primidone; Quality of Life; Valproic Acid | 1998 |
Cognitive effects of anticonvulsant monotherapy in elderly patients: a placebo-controlled study.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Cognition Disorders; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Phenytoin; Valproic Acid | 1998 |
An active-control trial of lamotrigine monotherapy for partial seizures.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Double-Blind Method; Epilepsies, Partial; Exanthema; Female; Humans; Hydrogen Peroxide; Lamotrigine; Male; Middle Aged; Phenytoin; Triazines; Valproic Acid | 1998 |
Does withdrawal of different antiepileptic drugs have different effects on seizure recurrence? Further results from the MRC Antiepileptic Drug Withdrawal Study.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Combinations; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Proportional Hazards Models; Recurrence; Risk Assessment; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1999 |
Spotlight on the continual applicability of routine plasma monitoring antiepileptic drugs in the treatment of epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Retrospective Studies; Valproic Acid | 1999 |
Safety and tolerability of gabapentin as adjunctive therapy in a large, multicenter study.
Topics: Acetates; Adolescent; Adult; Ambulatory Care; Amines; Anticonvulsants; Asthenia; Carbamazepine; Cyclohexanecarboxylic Acids; Dizziness; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Male; Patient Dropouts; Phenytoin; Prospective Studies; Treatment Outcome; Valproic Acid | 1999 |
Comparative double blind clinical trial of phenytoin and sodium valproate as anticonvulsant prophylaxis after craniotomy: efficacy, tolerability, and cognitive effects.
Topics: Adult; Aged; Brain Diseases; Cognition; Craniotomy; Double-Blind Method; Epilepsy; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Phenytoin; Quality of Life; Time Factors; Valproic Acid | 1999 |
Valproate therapy for prevention of posttraumatic seizures: a randomized trial.
Topics: Adult; Anticonvulsants; Blood Coagulation Disorders; Brain Injuries; Chemical and Drug Induced Liver Injury; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenytoin; Seizures; Valproic Acid | 1999 |
Effect of felbamate on clobazam and its metabolite kinetics in patients with epilepsy.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Epilepsies, Partial; Felbamate; Female; Humans; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Prospective Studies; Triazines; Valproic Acid | 1999 |
Influence of vitamin D administration on bone ultrasound measurements in patients on anticonvulsant therapy.
Topics: 25-Hydroxyvitamin D 2; Adult; Aged; Anticonvulsants; Bone and Bones; Calcifediol; Carbamazepine; Epilepsy; Female; Fingers; Humans; Male; Middle Aged; Osteomalacia; Parathyroid Hormone; Phenytoin; Ultrasonography; Valproic Acid; Vitamin D | 2000 |
[Gabitril as an additive drug in therapy of intractable epileptic seizures in children].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Generalized; Felbamate; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Nipecotic Acids; Nitrazepam; Oxcarbazepine; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Triazines; Valproic Acid; Vigabatrin | 2000 |
[Evaluation of antiepileptic therapy during pregnancy].
Topics: Adult; Anticonvulsants; Apgar Score; Drug Therapy, Combination; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Primidone; Valproic Acid | 2002 |
Topiramate therapeutic monitoring in patients with epilepsy: effect of concomitant antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Phenobarbital; Phenytoin; Prospective Studies; Topiramate; Triazines; Valproic Acid | 2002 |
A comparison of anticonvulsants in the treatment of impulsive aggression.
Topics: Adult; Aggression; Anticonvulsants; Carbamazepine; Double-Blind Method; Female; Humans; Impulsive Behavior; Intelligence Tests; Male; Phenytoin; Psychiatric Status Rating Scales; Valproic Acid | 2005 |
Intravenous valproate as an innovative therapy in seizure emergency situations including status epilepticus--experience in 102 adult patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Benzodiazepines; Female; Humans; Injections, Intravenous; Male; Middle Aged; Phenytoin; Prospective Studies; Reaction Time; Retrospective Studies; Seizures; Status Epilepticus; Time Factors; Treatment Outcome; Valproic Acid | 2005 |
Sodium valproate vs phenytoin in status epilepticus: a pilot study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Female; Humans; India; Male; Middle Aged; Phenytoin; Pilot Projects; Status Epilepticus; Treatment Outcome; Valproic Acid | 2006 |
In utero antiepileptic drug exposure: fetal death and malformations.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Cognition; Female; Fetal Death; Humans; Lamotrigine; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Triazines; Uterus; Valproic Acid | 2006 |
Interactions of serum albumin, valproic acid and carbamazepine with the pharmacokinetics of phenytoin in cancer patients.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Algorithms; Analysis of Variance; Antineoplastic Agents, Hormonal; Carbamazepine; Creatinine; Dexamethasone; Female; Humans; Injections, Intravenous; Male; Middle Aged; Models, Biological; Neoplasms; Phenytoin; Retrospective Studies; Serum Albumin; Tissue Distribution; Valproic Acid | 2006 |
Randomized study of intravenous valproate and phenytoin in status epilepticus.
Topics: Adolescent; Adult; Anticonvulsants; Case-Control Studies; Child; Double-Blind Method; Female; Follow-Up Studies; Humans; Injections, Intravenous; Male; Phenytoin; Retrospective Studies; Status Epilepticus; Treatment Outcome; Valproic Acid | 2007 |
Treatment of status epilepticus and acute repetitive seizures with i.v. valproic acid vs phenytoin.
Topics: Acute Disease; Adult; Aged; Anticonvulsants; Brain; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Epilepsy; Female; Humans; Injections, Intravenous; Male; Metabolic Clearance Rate; Middle Aged; Phenytoin; Prospective Studies; Secondary Prevention; Status Epilepticus; Treatment Outcome; Valproic Acid | 2008 |
Comparative efficacy and safety of intravenous valproate and phenytoin in children.
Topics: Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Phenytoin; Pilot Projects; Seizures; Treatment Outcome; Valproic Acid | 2011 |
Bayesian adaptive trials offer advantages in comparative effectiveness trials: an example in status epilepticus.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Bayes Theorem; Child; Child, Preschool; Comparative Effectiveness Research; Early Termination of Clinical Trials; Emergency Service, Hospital; Humans; Intention to Treat Analysis; Levetiracetam; Middle Aged; Models, Statistical; Phenytoin; Piracetam; Randomized Controlled Trials as Topic; Research Design; Status Epilepticus; Treatment Outcome; Valproic Acid; Young Adult | 2013 |
The established status epilepticus trial 2013.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Child; Child, Preschool; Double-Blind Method; Humans; Levetiracetam; Middle Aged; Phenytoin; Piracetam; Research Design; Status Epilepticus; Treatment Outcome; Valproic Acid; Young Adult | 2013 |
Management of generalised convulsive status epilepticus (SE): A prospective randomised controlled study of combined treatment with intravenous lorazepam with either phenytoin, sodium valproate or levetiracetam--Pilot study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Drug Therapy, Combination; Electroencephalography; Epilepsy, Generalized; Female; Follow-Up Studies; Humans; Injections, Intravenous; Levetiracetam; Lorazepam; Male; Middle Aged; Phenytoin; Pilot Projects; Piracetam; Prognosis; Prospective Studies; Status Epilepticus; Treatment Outcome; Valproic Acid; Young Adult | 2015 |
A comparison of four antiepileptic drugs in status epilepticus: experience from India.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Female; Humans; India; Infant; Levetiracetam; Lorazepam; Male; Middle Aged; Outcome Assessment, Health Care; Phenytoin; Piracetam; Status Epilepticus; Valproic Acid; Young Adult | 2016 |
Carnitine and/or Acetylcarnitine Deficiency as a Cause of Higher Levels of Ammonia.
Topics: Acetylcarnitine; Adolescent; Adult; Aged; Aged, 80 and over; Ammonia; Bipolar Disorder; Carnitine; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 2016 |
Sodium valproate compared to phenytoin in treatment of status epilepticus.
Topics: Adult; Aged; Anticonvulsants; Benzodiazepines; Drug Resistance; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Phenytoin; Status Epilepticus; Treatment Outcome; Valproic Acid; Young Adult | 2018 |
Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Double-Blind Method; Drug Resistance; Female; Humans; Hypotension; Infusions, Intravenous; Injections, Intramuscular; Levetiracetam; Male; Middle Aged; Phenytoin; Status Epilepticus; Valproic Acid; Young Adult | 2019 |
Comparison of Phenytoin, Valproate and Levetiracetam in Pediatric Convulsive Status Epilepticus: A Randomized Double-blind Controlled Clinical Trial.
Topics: Anticonvulsants; Child; Child, Preschool; Double-Blind Method; Female; Humans; Infant; Intention to Treat Analysis; Levetiracetam; Male; Phenytoin; Status Epilepticus; Treatment Outcome; Valproic Acid | 2020 |
Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial.
Topics: Adolescent; Adult; Age Distribution; Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Infant; Levetiracetam; Male; Middle Aged; Phenytoin; Status Epilepticus; Valproic Acid; Young Adult | 2020 |
The association of patient weight and dose of fosphenytoin, levetiracetam, and valproic acid with treatment success in status epilepticus.
Topics: Adolescent; Adult; Anticonvulsants; Body Weight; Dose-Response Relationship, Drug; Female; Humans; Levetiracetam; Male; Phenytoin; Single-Blind Method; Status Epilepticus; Treatment Outcome; Valproic Acid; Young Adult | 2020 |
Early Exposure of Fosphenytoin, Levetiracetam, and Valproic Acid After High-Dose Intravenous Administration in Young Children With Benzodiazepine-Refractory Status Epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Levetiracetam; Male; Phenytoin; Protein Binding; Status Epilepticus; Valproic Acid | 2021 |
Efficacy of Home Anticonvulsant Administration for Second-Line Status Epilepticus Treatment.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Child; Comparative Effectiveness Research; Double-Blind Method; Drug Resistant Epilepsy; Drug Therapy, Combination; Female; Humans; Levetiracetam; Male; Middle Aged; Outcome Assessment, Health Care; Phenytoin; Self Administration; Status Epilepticus; Valproic Acid; Young Adult | 2021 |
Treatment of Toxin-Related Status Epilepticus With Levetiracetam, Fosphenytoin, or Valproate in Patients Enrolled in the Established Status Epilepticus Treatment Trial.
Topics: Adult; Alcoholism; Analgesics, Opioid; Anticonvulsants; Benzodiazepines; Child; Cocaine; Female; Humans; Levetiracetam; Male; Phenytoin; Prospective Studies; Seizures; Status Epilepticus; Substance Withdrawal Syndrome; Valproic Acid | 2022 |
793 other study(ies) available for phenytoin and valproic acid
| Article | Year |
|---|---|
Structure-activity studies on benzhydrol-containing nipecotic acid and guvacine derivatives as potent, orally-active inhibitors of GABA uptake.
Topics: Administration, Oral; Animals; Anticonvulsants; Benzhydryl Compounds; Blood-Brain Barrier; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Mice; Neurotransmitter Uptake Inhibitors; Nicotinic Acids; Nipecotic Acids; Proline; Rats; Structure-Activity Relationship | 1992 |
Synthesis and anticonvulsant activity of enaminones.
Topics: Amines; Animals; Anticonvulsants; Drug Evaluation, Preclinical; Electric Stimulation; Kindling, Neurologic; Male; Mice; Rats; Seizures; Structure-Activity Relationship | 1992 |
2-Phenyl-3H-imidazo[4,5-b]pyridine-3-acetamides as non-benzodiazepine anticonvulsants and anxiolytics.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Benzodiazepines; Binding, Competitive; Cerebral Cortex; gamma-Aminobutyric Acid; Imidazoles; Mice; Mice, Inbred ICR; Molecular Structure; Pyridines; Rats; Receptors, GABA-A; Seizures | 1991 |
Preparation and anticonvulsant activity of a series of functionalized alpha-heteroatom-substituted amino acids.
Topics: Acetamides; Amino Acids; Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Electroshock; Male; Mice; Molecular Structure; Nitrogen; Oxygen; Seizures; Structure-Activity Relationship; Sulfur | 1991 |
Synthesis and anticonvulsant activity of imidooxy derivatives.
Topics: Animals; Anticonvulsants; Chickens; Electroshock; Imides; Indicators and Reagents; Molecular Structure; Phthalimides; Reflex; Structure-Activity Relationship; Succinimides | 1991 |
2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Gerbillinae; Hippocampus; Hypoxia; Male; Mice; Neurons; Phencyclidine; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Triazoles | 1990 |
Preparation and anticonvulsant activity of a series of functionalized alpha-aromatic and alpha-heteroaromatic amino acids.
Topics: Amino Acids; Animals; Anticonvulsants; Male; Mice; Structure-Activity Relationship | 1990 |
Synthesis and anticonvulsant activity of 2-benzylglutarimides.
Topics: Animals; Anticonvulsants; Benzyl Compounds; Mice; Piperidines; Piperidones; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1990 |
Metabolism of 3-(p-chlorophenyl)pyrrolidine. Structural effects in conversion of a prototype gamma-aminobutyric acid prodrug to lactam and gamma-aminobutyric acid type metabolites.
Topics: Amino Acids; Animals; Baclofen; Brain; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; gamma-Aminobutyric Acid; Isoniazid; Lactams; Liver; Male; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Molecular Structure; Monoamine Oxidase; Oxidation-Reduction; Prodrugs; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1989 |
Synthesis and anticonvulsant properties of 2,3,3a,4-tetrahydro-1H-pyrrolo[1,2-a]benzimidazol-1-ones.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Benzimidazoles; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Electroshock; Female; Male; Mice; Mice, Inbred DBA; Pyrrolidinones; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1989 |
Triazolines. 14. 1,2,3-Triazolines and triazoles, a new class of anticonvulsants. Drug design and structure-activity relationships.
Topics: Animals; Anticonvulsants; Electroshock; Mice; Seizures; Structure-Activity Relationship; Triazoles | 1988 |
Anticonvulsant activity of 2- and 3-aminobenzanilides.
Topics: Anilides; Aniline Compounds; Animals; Anticonvulsants; Electroshock; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures | 1986 |
Functionalized DL-amino acid derivatives. Potent new agents for the treatment of epilepsy.
Topics: Amino Acids; Animals; Anticonvulsants; Epilepsy; Magnetic Resonance Spectroscopy; Male; Mice; Seizures; Stereoisomerism; Structure-Activity Relationship | 1987 |
Anticonvulsant activity of some 4-aminobenzanilides.
Topics: Anilides; Animals; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Electroshock; Male; Mice; Pentylenetetrazole; Seizures; Structure-Activity Relationship | 1985 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Potential anticonvulsants. 1. 5-Benzylhydantoins.
Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Hydantoins; Male; Mice; Rats; Seizures; Structure-Activity Relationship | 1981 |
Synthesis and anticonvulsant activities of alpha-acetamido-N-benzylacetamide derivatives containing an electron-deficient alpha-heteroaromatic substituent.
Topics: Acetamides; Animals; Anticonvulsants; Male; Mice; Structure-Activity Relationship | 1994 |
Synthesis and anticonvulsant activities of alpha-heterocyclic alpha-acetamido-N-benzylacetamide derivatives.
Topics: Acetamides; Animals; Anticonvulsants; Benzeneacetamides; Benzyl Compounds; Furans; Heterocyclic Compounds; Male; Mice; Mice, Inbred Strains; Seizures; Stereoisomerism; Structure-Activity Relationship | 1993 |
Synthesis and CLOGP correlation of imidooxy anticonvulsants.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Electroshock; Male; Mice; Models, Molecular; Molecular Structure; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Seizures; Spiro Compounds; Structure-Activity Relationship | 1993 |
5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents.
Topics: Animals; Anticonvulsants; Cerebellum; Cerebral Cortex; Chlorides; Electroshock; Flumazenil; Male; Mice; Molecular Structure; Muscle Spasticity; Paralysis; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship; Strychnine; Triazoles | 1994 |
Synthesis and anticonvulsant activities of N-Benzyl-2-acetamidopropionamide derivatives.
Topics: Acetamides; Animals; Anticonvulsants; Benzylamines; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1996 |
Synthesis and evaluation of N-(phenylacetyl)trifluoromethanesulfonamides as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Body Weight; Cytochrome P-450 Enzyme System; Epilepsy; Mesylates; Mice; NADPH-Ferrihemoprotein Reductase; Organ Size; Oxidoreductases, O-Demethylating; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides | 1996 |
(Aryloxy)aryl semicarbazones and related compounds: a novel class of anticonvulsant agents possessing high activity in the maximal electroshock screen.
Topics: Animals; Anticonvulsants; Binding Sites; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Hydrogen Bonding; Mice; Models, Molecular; Molecular Structure; Pentylenetetrazole; Rats; Seizures; Semicarbazones; Structure-Activity Relationship | 1996 |
Aroyl(aminoacyl)pyrroles, a new class of anticonvulsant agents.
Topics: Anesthesia; Animals; Anticonvulsants; Bicuculline; Calcium; Cerebellum; Electroshock; Mice; Models, Molecular; Molecular Structure; Pentylenetetrazole; Piperidines; Potassium; Pyrroles; Rats; Seizures; Structure-Activity Relationship; Veratridine | 1997 |
N-(benzyloxycarbonyl)glycine esters and amides as new anticonvulsants.
Topics: 3-Mercaptopropionic Acid; Amides; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Esters; Glycine; Male; Mice; Mice, Inbred Strains; Neurotoxins; Pentylenetetrazole; Radioligand Assay; Rats; Rats, Wistar; Receptors, Glycine; Seizures; Spinal Cord; Strychnine | 1998 |
Synthesis and anticonvulsant activity of a new class of 2-[(arylalky)amino]alkanamide derivatives.
Topics: Alanine; Animals; Anticonvulsants; Benzylamines; Bicuculline; Drug Design; Electroshock; Indicators and Reagents; Male; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Structure; Motor Activity; Picrotoxin; Postural Balance; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship; Strychnine | 1998 |
Synthesis and anticonvulsant activity of 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives.
Topics: Animals; Anticonvulsants; Electric Stimulation; Injections, Intraperitoneal; Male; Mice; Oxazoles; Rats; Seizures; Thiazoles | 1998 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Synthesis and structural studies of aza analogues of functionalized amino acids: new anticonvulsant agents.
Topics: Animals; Anticonvulsants; Aza Compounds; Crystallography, X-Ray; Electroshock; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Rats; Seizures; Semicarbazides; Structure-Activity Relationship | 2001 |
Design and evaluation of affinity labels of functionalized amino acid anticonvulsants.
Topics: Affinity Labels; Amino Acids; Animals; Anticonvulsants; Electroshock; Isothiocyanates; Mice; Radioligand Assay; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship | 2002 |
Synthesis and anticonvulsant activity of novel bicyclic acidic amino acids.
Topics: Amino Acids, Acidic; Amino Acids, Dicarboxylic; Animals; Anticonvulsants; Cerebral Cortex; CHO Cells; Cricetinae; Crystallography, X-Ray; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heterocyclic Compounds, 2-Ring; In Vitro Techniques; Isoxazoles; Male; Mice; Mice, Inbred DBA; Molecular Conformation; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 2003 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Synthesis and anticonvulsant activity of 7-alkoxyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolines.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Mice; Neurotoxicity Syndromes; Quinolines; Seizures; Structure-Activity Relationship | 2005 |
Discovery of N-(2,6-dimethylphenyl)-substituted semicarbazones as anticonvulsants: hybrid pharmacophore-based design.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Benzamides; Chemical and Drug Induced Liver Injury; Drug Design; Female; gamma-Aminobutyric Acid; Male; Mice; Models, Molecular; Motor Activity; Rats; Seizures; Semicarbazones; Structure-Activity Relationship | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Synthesis and anticonvulsant activity of sulfonamide derivatives-hydrophobic domain.
Topics: Animals; Anticonvulsants; Hydrophobic and Hydrophilic Interactions; Male; Mice; Mice, Inbred Strains; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfonamides | 2007 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Inhibition of aquaporin 4 by antiepileptic drugs.
Topics: Animals; Anticonvulsants; Aquaporin 4; Computer Simulation; Drug Evaluation, Preclinical; Humans; Oocytes; Protein Binding; Thermodynamics; Xenopus | 2009 |
Synthesis of some novel N4-(naphtha[1,2-d]thiazol-2-yl)semicarbazides as potential anticonvulsants.
Topics: Animals; Anticonvulsants; Brain Chemistry; Glutathione Peroxidase; Malondialdehyde; Mice; Motor Activity; Rats; Seizures; Semicarbazides; Structure-Activity Relationship; Superoxide Dismutase | 2009 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Design and synthesis of 6-amino-1,4-oxazepane-3,5-dione derivatives as novel broad spectrum anticonvulsants.
Topics: Animals; Anticonvulsants; Combinatorial Chemistry Techniques; Drug Design; Electroshock; Male; Mice; Molecular Structure; Oxazepines; Pentylenetetrazole; Seizures | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.
Topics: Amides; Animals; Anticonvulsants; Carbonic Anhydrase II; Cell Line; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Male; Mice; Rats; Sulfonamides; Thiophenes | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Combating oxidative stress in epilepsy: design, synthesis, quantum chemical studies and anticonvulsant evaluation of 1-(substituted benzylidene/ethylidene)-4-(naphthalen-1-yl)semicarbazides.
Topics: Animals; Anticonvulsants; Antioxidants; Benzylidene Compounds; Drug Design; Electrons; Epilepsy; Male; Mice; Oxidative Stress; Quantum Theory; Semicarbazides | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
The structure-activity relationship of the 3-oxy site in the anticonvulsant (R)-N-benzyl 2-acetamido-3-methoxypropionamide.
Topics: Acetamides; Animals; Anticonvulsants; Electroshock; Hydrophobic and Hydrophilic Interactions; Lacosamide; Male; Mice; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Primary amino acid derivatives: compounds with anticonvulsant and neuropathic pain protection activities.
Topics: Amino Acids; Analgesics; Animals; Anticonvulsants; Convulsants; Electroshock; Formaldehyde; Male; Mice; Neuralgia; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship | 2011 |
Synthesis and anticonvulsant activity of trans- and cis-2-(2,6-dimethylphenoxy)-N-(2- or 4-hydroxycyclohexyl)acetamides and their amine analogs.
Topics: Acetamides; Amines; Animals; Anticonvulsants; Mice; Rats; Seizures | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Synthesis and anticonvulsant activity of ethyl 1-(2-arylhydrazinecarboxamido)-2,2-dimethylcyclopropanecarboxylate derivatives.
Topics: Animals; Anticonvulsants; Chemistry Techniques, Synthetic; Hydrazines; Male; Mice; Motor Activity; Rotarod Performance Test; Seizures | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
(Biphenyl-4-yl)methylammonium chlorides: potent anticonvulsants that modulate Na+ currents.
Topics: Ammonium Compounds; Animals; Anticonvulsants; Biphenyl Compounds; Male; Methylamines; Mice; Rats; Rats, Sprague-Dawley; Sodium Channels | 2013 |
Design, synthesis and anticonvulsant properties of new N-Mannich bases derived from 3-phenylpyrrolidine-2,5-diones.
Topics: Administration, Oral; Animals; Anticonvulsants; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Disease Models, Animal; Drug Design; Electroshock; Humans; Male; Mannich Bases; Mice; Microsomes, Liver; Motor Activity; Pentylenetetrazole; Protein Binding; Pyrrolidines; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship | 2013 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).
Topics: Absorption; Amides; Animals; Anticonvulsants; Dioxanes; Dogs; Drug Evaluation, Preclinical; Drug Resistance; Epilepsy; Female; Humans; Male; Mice; Rats; Sulfonamides | 2013 |
Design, synthesis and pharmacological evaluation of N-[4-(4-(alkyl/aryl/heteroaryl)-piperazin-1-yl)-phenyl]-carbamic acid ethyl ester derivatives as novel anticonvulsant agents.
Topics: Animals; Anticonvulsants; Carbamates; Drug Design; Electroshock; Epilepsy; Mice; Pentylenetetrazole; Piperazine; Piperazines; Seizures | 2015 |
Chimeric derivatives of functionalized amino acids and α-aminoamides: compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels.
Topics: Acetamides; Administration, Oral; Amides; Amino Acids; Animals; Anticonvulsants; Cerebral Cortex; Electroshock; HEK293 Cells; Humans; Injections, Intraperitoneal; Male; Mice; Neurons; Patch-Clamp Techniques; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship; Voltage-Gated Sodium Channel Blockers; Voltage-Gated Sodium Channels | 2015 |
Design, synthesis and biological activity of new amides derived from 3-methyl-3-phenyl-2,5-dioxo-pyrrolidin-1-yl-acetic acid.
Topics: Acetates; Amides; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Electroshock; Injections, Intraperitoneal; Mice; Molecular Structure; Pyrrolidines; Seizures | 2015 |
Synthesis of 2,6-dicarbethoxy-3,5-diaryltetrahydro-1,4-thiazine-1,1-dioxide derivatives as potent anticonvulsant agents.
Topics: Animals; Anticonvulsants; Crystallography, X-Ray; Cyclic S-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Injections, Intraperitoneal; Mice; Models, Molecular; Molecular Structure; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Thiazines | 2015 |
Synthesis, and anticonvulsant activity of new amides derived from 3-methyl- or 3-ethyl-3-methyl-2,5-dioxo-pyrrolidin-1-yl-acetic acids.
Topics: Amides; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Molecular Structure; Pentylenetetrazole; Pyrrolidines; Seizures | 2016 |
Design, synthesis and anticonvulsant-analgesic activity of new
Topics: | 2017 |
Novel benzothiazole hydrazine carboxamide hybrid scaffolds as potential in vitro GABA AT enzyme inhibitors: Synthesis, molecular docking and antiepileptic evaluation.
Topics: Anticonvulsants; Hydrazines; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2019 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
[Adverse effects of anti-epileptic drugs].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Mephenytoin; Nitrazepam; Phenytoin; Primidone; Succinimides; Thiazines; Trimethadione; Valproic Acid | 1975 |
Prognosis and therapy of complex partial seizures with barbiturates, hydantoins, and other drugs.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Prognosis; Succinimides; Thiazines; Valproic Acid | 1975 |
Effect of sodium valproate on plasma protein binding of diphenylhydantoin.
Topics: Animals; Blood Proteins; Brain; Drug Interactions; Ethosuximide; In Vitro Techniques; Injections, Intraperitoneal; Male; Phenytoin; Protein Binding; Rats; Thiazines; Valerates; Valproic Acid | 1977 |
[Drug interactions in antiepileptic combination therapy].
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Thiazines; Time Factors; Urea; Valproic Acid | 1979 |
Use of anticonvulsant drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Valproate may lower serum-phenytoin.
Topics: Animals; Brain Chemistry; Drug Combinations; Humans; In Vitro Techniques; Injections, Intraperitoneal; Phenytoin; Rats; Time Factors; Valerates; Valproic Acid | 1977 |
Valproate may lower serum-phenytoin.
Topics: Drug Interactions; Epilepsy; Humans; Phenytoin; Valerates; Valproic Acid | 1976 |
Valproate may lower serum-phenytoin.
Topics: Humans; Phenytoin; Valerates; Valproic Acid | 1977 |
Effects of anticonvulsant drugs on thyroid hormones in epileptic children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Cholesterol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Primidone; Protein Binding; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine; Valproic Acid | 1978 |
[Pharmacological influence of valproate on phenobarbitone and phenytoin serum concentrations in epileptic patients (author's transl)].
Topics: Drug Interactions; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1979 |
Effect of phenytoin on protein binding of valproic acid.
Topics: Humans; Phenytoin; Protein Binding; Valproic Acid | 1979 |
Valproic acid: in vitro plasma protein binding and interaction with phenytoin.
Topics: Blood Proteins; Drug Interactions; Humans; In Vitro Techniques; Phenytoin; Protein Binding; Saliva; Serum Albumin; Valproic Acid | 1979 |
Febrile seizures and thalamocortical activity: a comparison of effects of valproate and phenytoin.
Topics: Animals; Cats; Cerebral Cortex; Neural Pathways; Phenytoin; Seizures; Seizures, Febrile; Thalamus; Valproic Acid | 1979 |
Valproic acid-phenytoin interaction.
Topics: Adult; Chromatography, Gas; Drug Interactions; Epilepsy; Humans; Monitoring, Physiologic; Phenytoin; Protein Binding; Valproic Acid | 1979 |
[Drug therapy of epilepsy].
Topics: Age Factors; Anticonvulsants; Barbiturates; Benzodiazepines; Bromides; Carbamazepine; Chlormethiazole; Contraceptives, Oral; Diabetes Mellitus; Enzyme Induction; Epilepsy; Female; Humans; Kidney Failure, Chronic; Lactation; Microsomes, Liver; Phenytoin; Postpartum Period; Pregnancy; Valproic Acid | 1977 |
Drug interactions during anticonvulsant therapy in childhood: diphenylhydantoin, primidone, phenobarbitone, clonazepam, nitrazepam, carbamazepin and dipropylacetate.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Nitrazepam; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1977 |
Management of childhood epilepsy.
Topics: Child; Epilepsy; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1977 |
Implications of measuring anticonvulsant blood levels in epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Epilepsy; Humans; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Valproic Acid | 1977 |
Preliminary observations on valproic acid kinetics in patients with epilepsy.
Topics: Adult; Child; Chromatography, Gas; Epilepsy; Humans; Phenobarbital; Phenytoin; Valerates; Valproic Acid | 1977 |
Changes in sensitivity of mice to anticonvulsant drugs following bilateral olfactory bulb ablations.
Topics: Acetazolamide; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Nitrazepam; Olfactory Bulb; Phenobarbital; Phenylacetates; Phenytoin; Trimethadione; Urea; Valproic Acid | 1977 |
Epilepsy and IgA deficiency--the effect of sodium valproate.
Topics: Adult; Agammaglobulinemia; Carbamazepine; Epilepsy; Female; Humans; Immunoglobulin A; Male; Phenobarbital; Phenytoin; Valerates; Valproic Acid | 1977 |
Choice of drug therapy in epilepsy.
Topics: Acetazolamide; Anticonvulsants; Benzodiazepines; Carbamazepine; Clonazepam; Epilepsy; Ethosuximide; Humans; Nitrazepam; Phenobarbital; Phenytoin; Valproic Acid | 1977 |
[Plasma levels of anticonvulsants. Experiences with routine plasma level determination of 6 different anticonvulsants].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
Serum protein binding of diphenylhydantoin in man. I. Interaction with sodium valproate.
Topics: Drug Interactions; Epilepsy; Humans; In Vitro Techniques; Phenytoin; Protein Binding; Valerates; Valproic Acid | 1978 |
Effect of anticonvulsants on thalamic afterdischarge in rats and cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Diazepam; Electrocardiography; Electroencephalography; Female; Male; Phenobarbital; Phenytoin; Rats; Thalamus; Trimethadione; Valproic Acid | 1977 |
Thyroid function tests in patients on long-term treatment with various anticonvulsant drugs.
Topics: Adolescent; Adult; Carbamazepine; Female; Humans; Male; Middle Aged; Phenytoin; Primidone; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine; Valproic Acid | 1978 |
[Ultrastructural changes of murine cerebellum after anticonvulsant administration. I. Acute intoxication (author's transl)].
Topics: Acute Disease; Animals; Anticonvulsants; Cerebellum; Mice; Phenytoin; Primidone; Valproic Acid | 1977 |
Long-term use of the major anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Time Factors; Valproic Acid | 1978 |
Pharmacological actions on hypoxic increase of rat brain cortex extracellular K+ ion.
Topics: Animals; Cerebral Cortex; Extracellular Space; Hypoxia; Male; Phenytoin; Potassium; Propranolol; Pyrithioxin; Rats; Stereoisomerism; Valproic Acid; Vincamine | 1978 |
Plasma protein binding interaction between phenytoin and valproic acid in vitro.
Topics: Binding Sites; Blood Proteins; Drug Interactions; Humans; In Vitro Techniques; Kinetics; Phenytoin; Protein Binding; Valproic Acid | 1978 |
Consecutive gas chromatographic determination of phenytoin, phenobarbital, primidone, phenylethylmalondiamide, carbamazepine, trimethadione, dimethadione, ethosuximide, and valproate from the same serum specimen.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Dimethadione; Ethosuximide; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Trimethadione; Valproic Acid | 1978 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Status Epilepticus; Valproic Acid | 1979 |
Effect of anticonvulsants on spiking activity induced by cortical freezing in cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Arousal; Carbamazepine; Cats; Diazepam; Electrocardiography; Electroencephalography; Female; Freezing; Gallamine Triethiodide; Immobilization; Male; Phenobarbital; Phenytoin; Taurine; Trimethadione; Valproic Acid; Visual Cortex | 1979 |
Valproic acid binding to human serum albumin and determination of free fraction in the presence of anticonvulsants and free fatty acids.
Topics: Anticonvulsants; Carbamazepine; Fatty Acids, Nonesterified; Humans; Linoleic Acids; Oleic Acids; Palmitic Acids; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Stearic Acids; Valproic Acid | 1979 |
Recent advances in drug therapy for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Drug Interactions; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
The use of antiepileptic drugs.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Comparative trial of valproate sodium and clonazepam in chronic epilepsy.
Topics: Adult; Ataxia; Benzodiazepinones; Chronic Disease; Clonazepam; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sleep Stages; Sleep Wake Disorders; Valproic Acid | 1979 |
The drug of choice for major seizures?
Topics: Carbamazepine; Decision Making; Humans; Phenytoin; Seizures; Valproic Acid | 1979 |
Valproic acid and plasma levels of phenytoin.
Topics: Drug Interactions; Drug Therapy, Combination; Humans; Phenytoin; Valproic Acid | 1979 |
Serum protein binding of diphenylhydantoin in man. II. Interaction with sodium valproate in epileptic patients.
Topics: Adult; Binding, Competitive; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Protein Binding; Valproic Acid | 1979 |
The therapeutic underpriviledged.
Topics: Carbamazepine; Child; Dosage Forms; Drug Administration Schedule; Humans; Phenytoin; Valproic Acid | 1979 |
Anticonvulsant therapy in childhood. Recent advances.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1979 |
[The serum concentration of anticonvulsants -- pharmacokinetic findings and practical therapeutic applications (author's transl)].
Topics: Antacids; Anticonvulsants; Biological Availability; Carbamazepine; Chromatography, Gas; Clonazepam; Dosage Forms; Ethosuximide; Half-Life; Humans; Immunoenzyme Techniques; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone; Seizures; Valproic Acid | 1979 |
Decreased plasma protein binding of phenytoin in patients on valproic acid.
Topics: Adolescent; Adult; Blood Proteins; Child; Creatinine; Depression, Chemical; Epilepsy; Humans; Phenytoin; Protein Binding; Serum Albumin; Urea; Valproic Acid | 1979 |
[Atypical petit mal status. Case contribution on diagnostic difficulties].
Topics: Adult; Cerebral Ventricle Neoplasms; Diagnostic Errors; Electroencephalography; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Male; Phenytoin; Tomography, X-Ray Computed; Valproic Acid | 1977 |
Effect of anticonvulsants on cortical focal seizure in cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Diazepam; Electrocardiography; Epilepsies, Partial; Female; Heart; Male; Phenobarbital; Phenytoin; Seizures; Trimethadione; Valproic Acid | 1977 |
[Measurement of the blood concentration of antiepileptic drugs. II Special cases].
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1975 |
[Reflections on temporal epilepsy in the child].
Topics: Adolescent; Anticonvulsants; Epilepsy, Temporal Lobe; Humans; Male; Phenobarbital; Phenytoin; Social Behavior Disorders; Valproic Acid | 1976 |
Proposals on antiepileptic pharmacotherapy for use in developing countries.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Developing Countries; Diazepam; Epilepsy; Ethosuximide; Humans; Infant; Phenobarbital; Phenytoin; Valproic Acid | 1976 |
Sodium valproate in the treatment of resistant epilepsy.
Topics: Adolescent; Adult; Alopecia; Anticonvulsants; Body Weight; Diarrhea; Drug Interactions; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Male; Nausea; Phenobarbital; Phenytoin; Valerates; Valproic Acid; Vomiting | 1976 |
The photically evoked afterdischarge: a model for the study of drugs useful in the treatment of petit mal epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy, Absence; Evoked Potentials; Female; Pentylenetetrazole; Phenytoin; Rats; Sodium Chloride; Trimethadione; Valproic Acid | 1976 |
Letter: Sodium valproate in the treatment of intractable childhood epilepsy.
Topics: Diazepam; Drug Therapy, Combination; Epilepsy; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Valerates; Valproic Acid | 1975 |
Elevation of diphenylhydantoin and primidone serum concentration by addition of dipropylacetate, a new anticonvulsant drug.
Topics: Child; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Primidone; Valerates; Valproic Acid | 1975 |
Pharmacokinetic interaction of zonisamide in rats. Effect of other antiepileptics on zonisamide.
Topics: Administration, Oral; Animals; Anticonvulsants; Blood Proteins; Diethylcarbamazine; Drug Interactions; Erythrocytes; Half-Life; Isoxazoles; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Valproic Acid; Zonisamide | 1992 |
Treatment of epilepsy.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Male; Phenytoin; Valproic Acid | 1992 |
Influence of phenytoin and valproate on thalamocortical evoked potentials and their paired-pulse potentiation.
Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials, Somatosensory; Injections, Intraperitoneal; Male; Phenytoin; Rats; Rats, Wistar; Thalamus; Time Factors; Valproic Acid | 1992 |
Cognitive functions, epileptic syndromes and antiepileptic drugs.
Topics: Adolescent; Adult; Carbamazepine; Child; Cognition; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Prospective Studies; Valproic Acid | 1992 |
Effects of Ca2+ antagonists and antiepileptics on tetrodotoxin-sensitive Ca(2+)-conducting channels in isolated rat hippocampal CA1 neurons.
Topics: Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Diltiazem; Dizocilpine Maleate; Dose-Response Relationship, Drug; Flunarizine; Hippocampus; Kinetics; Neurons; Nicardipine; Phenobarbital; Phenytoin; Pyramidal Tracts; Rats; Rats, Wistar; Sodium; Tetrodotoxin; Valproic Acid; Verapamil | 1992 |
What to do when the first anticonvulsant does not work.
Topics: Aminocaproates; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Lamotrigine; Phenytoin; Treatment Outcome; Triazines; Valproic Acid; Vigabatrin | 1992 |
Therapeutic drug monitoring improves seizure control and reduces anticonvulsant side-effects in patients with refractory epilepsy.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Monitoring; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Follow-Up Studies; Humans; Phenytoin; Retrospective Studies; Valproic Acid | 1992 |
Mechanisms of neurotransmission of valproate sodium in suppressing barbiturate and phenytoin withdrawal syndrome.
Topics: Animals; Barbiturates; Brain; Neurotransmitter Agents; Phenytoin; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Synaptic Transmission; Valproic Acid | 1992 |
Suppression of experimental barbiturate and phenytoin withdrawal syndrome using valproate sodium.
Topics: Animals; Barbiturates; Male; Phenytoin; Rats; Rats, Wistar; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1992 |
Effects of some calcium antagonists upon the activity of common antiepileptic compounds on sound-induced seizures in DBA/2 mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Body Temperature; Calcium Channel Blockers; Diltiazem; Drug Synergism; Flunarizine; Mice; Mice, Inbred DBA; Nimodipine; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Verapamil | 1992 |
Carbamyl phosphate synthetase-1 deficiency discovered after valproic acid-induced coma.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Ammonia; Atrophy; Carbamoyl-Phosphate Synthase (Ammonia); Coma; Corpus Callosum; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Generalized; Female; Glutamine; Humans; Phenytoin; Tomography, X-Ray Computed; Valproic Acid | 1992 |
Unresponsiveness to human recombinant erythropoietin in an epileptic dialysis patient secondary to valproic acid toxicity.
Topics: Adult; Electrocardiography; Epilepsy, Tonic-Clonic; Erythropoietin; Female; Humans; Kidney Failure, Chronic; Phenytoin; Recombinant Proteins; Renal Dialysis; Valproic Acid | 1992 |
Ring 14 chromosome with complex partial seizures: a case report.
Topics: Child; Chromosomes, Human, Pair 14; Electroencephalography; Epilepsy, Complex Partial; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Ring Chromosomes; Tomography, X-Ray Computed; Valproic Acid | 1992 |
Cerebral cavernous angioma: a potentially benign condition? Successful treatment in 16 cases.
Topics: Adolescent; Adult; Angiography; Brain Neoplasms; Carbamazepine; Cerebral Hemorrhage; Child; Epilepsy; Female; Hemangioma, Cavernous; Humans; Magnetic Resonance Imaging; Male; Phenobarbital; Phenytoin; Retrospective Studies; Seizures; Valproic Acid | 1992 |
Cognitive effects of antiepileptic drug discontinuation.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Epilepsy; Humans; Middle Aged; Neuropsychological Tests; Phenobarbital; Phenytoin; Psychomotor Performance; Valproic Acid | 1992 |
Intravenous valproate: onset and duration of anticonvulsant activity against a series of electroconvulsions in comparison with diazepam and phenytoin.
Topics: Animals; Anticonvulsants; Diazepam; Electric Stimulation; Electroshock; Epilepsy, Tonic-Clonic; Injections, Intravenous; Male; Mice; Phenytoin; Seizures; Valproic Acid | 1992 |
Age dependency of the susceptibility of rats to aminooxyacetic acid seizures.
Topics: Aging; Aminooxyacetic Acid; Animals; Anticonvulsants; Body Temperature; Brain; Carbamazepine; Clonazepam; Disease Susceptibility; Electroencephalography; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Organ Specificity; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Time Factors; Valproic Acid | 1992 |
Interactions between clobazam and standard antiepileptic drugs in patients with epilepsy.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Retrospective Studies; Valproic Acid | 1992 |
Rapid and sensitive liquid chromatographic assay of mefenamic acid in plasma.
Topics: Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Hydrogen-Ion Concentration; Indomethacin; Ketoprofen; Least-Squares Analysis; Mefenamic Acid; Phenobarbital; Phenytoin; Salicylates; Salicylic Acid; Sensitivity and Specificity; Valproic Acid | 1992 |
Unbound plasma phenytoin concentrations measured using enzyme immunoassay technique on the cobas MIRA analyser--in vivo effect of valproic acid.
Topics: Blood Proteins; Humans; Immunoenzyme Techniques; Phenytoin; Protein Binding; Valproic Acid | 1992 |
Segregation of the growth slowing effects of valproic acid from phenytoin and carbamazepine on lymphoid tumor cells.
Topics: Carbamazepine; Cell Division; Culture Techniques; Humans; Kinetics; Leukemia; Lymphoma; Phenytoin; Regression Analysis; Valproic Acid | 1992 |
Antiepileptic drug disposition during pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Valproic Acid | 1992 |
Epilepsy, antiepileptic drugs, and malformations in children of women with epilepsy: a French prospective cohort study.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Cohort Studies; Epilepsy; Female; Humans; Odds Ratio; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Prospective Studies; Valproic Acid | 1992 |
Antiepileptic drugs and teratogenesis in two consecutive cohorts: changes in prescription policy paralleled by changes in pattern of malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Drug Prescriptions; Epilepsy; Female; Humans; Infant; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 1992 |
Clinical utility of unbound antiepileptic drug blood levels in the management of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Valproic Acid | 1992 |
Effects of long-term anticonvulsant therapy on copper, zinc, and magnesium in hair and serum of epileptics.
Topics: Adult; Anticonvulsants; Carbamazepine; Copper; Drug Therapy, Combination; Epilepsy, Generalized; Female; Hair; Humans; Long-Term Care; Magnesium; Male; Middle Aged; Phenobarbital; Phenytoin; Schizophrenia; Valproic Acid; Zinc | 1992 |
A micro-enzyme-multiplied immunoassay technique plate assay for antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Female; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; NAD; Phenytoin; Valproic Acid | 1992 |
[Effect of anticonvulsants upon experimental limbic seizure status and regional cerebral blood flow in the hippocampus].
Topics: Animals; Anticonvulsants; Cats; Diazepam; Electroencephalography; Hippocampus; Isoxazoles; Phenobarbital; Phenytoin; Regional Blood Flow; Status Epilepticus; Valproic Acid; Zonisamide | 1992 |
Anticonvulsant-induced chronic pancreatitis. A case report.
Topics: Adult; Anticonvulsants; Carbamazepine; Chronic Disease; Cytochrome P-450 Enzyme System; Epilepsy; Free Radicals; Humans; Male; Pancreatitis; Phenytoin; Valproic Acid | 1992 |
The effects of anticonvulsant drugs on vitamin D3-activating cytochrome P-450-linked monooxygenase systems.
Topics: Animals; Biotransformation; Cholecalciferol; Cholestanetriol 26-Monooxygenase; Cytochrome P-450 Enzyme System; Ferredoxin-NADP Reductase; Ferredoxins; Isoenzymes; Kinetics; Male; Microsomes, Liver; Mitochondria, Liver; NADPH-Ferrihemoprotein Reductase; Phenytoin; Rabbits; Steroid Hydroxylases; Valproic Acid | 1991 |
Influence of antiepileptic drugs on sleep patterns.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Brain; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Long-Term Care; Male; Phenobarbital; Phenytoin; Retrospective Studies; Sleep Deprivation; Sleep Stages; Valproic Acid | 1991 |
Balance and cognitive impairment in two epileptic patients before and after vagal nerve stimulation.
Topics: Adult; Carbamazepine; Cognition; Electric Stimulation Therapy; Epilepsy, Temporal Lobe; Humans; Male; Parkinson Disease; Phenobarbital; Phenytoin; Postural Balance; Reaction Time; Time Factors; Vagus Nerve; Valproic Acid | 1991 |
Performance of fluorescence polarisation immunoassay reagents for carbamazepine, phenytoin, phenobarbitone, primidone, and valproic acid on a Cobas Fara II analyser.
Topics: Anticonvulsants; Carbamazepine; Evaluation Studies as Topic; Fluorescence Polarization Immunoassay; Humans; Phenobarbital; Phenytoin; Primidone; Reference Standards; Valproic Acid | 1991 |
Clinical evaluation of five therapeutic drugs using dry film multilayer technology on the OPUS immunoassay system.
Topics: Carbamazepine; Evaluation Studies as Topic; Humans; Immunoassay; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Reference Standards; Sensitivity and Specificity; Theophylline; Valproic Acid | 1991 |
[Evaluation of the effectiveness of monotherapy in the treatment of epilepsy].
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Drug Evaluation; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
Wild running and switch-off behavior elicited by electrical stimulation of the inferior colliculus: effect of anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Behavior, Animal; Conditioning, Operant; Diazepam; Electric Stimulation; Inferior Colliculi; Male; Motivation; Phenytoin; Rats; Rats, Inbred Strains; Running; Valproic Acid | 1991 |
[A case of upper brainstem infarction developing symptomatic narcolepsy after the administration of anti-convulsant drugs].
Topics: Brain Stem; Cerebral Infarction; Electroencephalography; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Narcolepsy; Phenytoin; Sleep, REM; Valproic Acid | 1991 |
Toxicology and kinetics of long-term intraventricular infusion of phenytoin and valproic acid in pigs: experimental study.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Injections, Intraventricular; Long-Term Care; Phenytoin; Swine; Valproic Acid | 1991 |
Anticonvulsant activity of the imidazoline 6,7-benzoidazoxan.
Topics: Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Dioxanes; Electroshock; Imidazoles; Male; Mice; Phenytoin; Postural Balance; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1991 |
The effect of administration time on malformations induced by three anticonvulsant agents in C57BL/6J mice with emphasis on forelimb ectrodactyly.
Topics: Abnormalities, Drug-Induced; Animals; Anophthalmos; Anticonvulsants; Dimethadione; Facial Bones; Female; Forelimb; Gestational Age; Kidney; Maternal Mortality; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Microphthalmos; Phenytoin; Pregnancy; Skull; Spine; Valproic Acid | 1991 |
Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.
Topics: Animals; Baclofen; Carbamazepine; Cricetinae; Diazepam; Disease Models, Animal; Dystonia; gamma-Aminobutyric Acid; Mesocricetus; Mutation; Pentylenetetrazole; Phenobarbital; Phenytoin; Synaptic Transmission; Valproic Acid | 1991 |
Liver damage in long-term anticonvulsant therapy: a serological and histological study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Humans; Isoantigens; Liver; Liver Diseases; Male; Middle Aged; Phenobarbital; Phenytoin; Retrospective Studies; Valproic Acid | 1991 |
Plasma uric acid in patients receiving anticonvulsant monotherapy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Phenobarbital; Phenytoin; Prospective Studies; Uric Acid; Valproic Acid | 1991 |
Increased microsomal irreversible binding of phenytoin by valproic acid.
Topics: Animals; Drug Interactions; Glutathione; Microsomes, Liver; Phenytoin; Protein Binding; Rats; Valproic Acid | 1991 |
Short-term effects of administration of anticonvulsant drugs on free carnitine and acylcarnitine in mouse serum and tissues.
Topics: Animals; Anticonvulsants; Carbamazepine; Carnitine; Heart; In Vitro Techniques; Male; Mice; Muscles; Myocardium; Phenobarbital; Phenytoin; Prohibitins; Valproic Acid | 1991 |
Alteration of renal carnitine metabolism by anticonvulsant treatment.
Topics: Ammonia; Animals; Anticonvulsants; Carbamazepine; Carnitine; Male; Mice; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
[Effects of antiepileptic drugs on delivery and early childhood--comparison among mono-therapies of valproic acid, phenytoin, carbamazepine and phenobarbital].
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Birth Weight; Carbamazepine; Embryonic and Fetal Development; Epilepsy; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Labor, Obstetric; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Spinal Dysraphism; Valproic Acid | 1991 |
Reduction of serum carnitine concentrations during anticonvulsant therapy with phenobarbital, valproic acid, phenytoin, and carbamazepine in children.
Topics: Analysis of Variance; Carbamazepine; Carnitine; Child; Drug Combinations; Fatty Acids; Fatty Acids, Volatile; Humans; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1991 |
Epileptic patients refractory to drug therapy.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Immunoglobulin G; Immunoglobulins; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
Effects of anticonvulsants and gamma-aminobutyric acid (GABA)-mimetic drugs on immunoreactive somatostatin and GABA contents in the rat brain.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Chromatography, Gel; Drug Interactions; Ethanolamines; gamma-Aminobutyric Acid; Male; Muscimol; Phenytoin; Rats; Rats, Inbred Strains; Somatostatin; Valproic Acid | 1990 |
Seizures: introduction and commentary.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
Nomogram for the prediction of unbound phenytoin concentrations in patients on a combined treatment of phenytoin and valproic acid.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Chromatography, Gas; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Epilepsy; Humans; Middle Aged; Phenytoin; Protein Binding; Regression Analysis; Valproic Acid | 1991 |
Effects of acute valproic acid administration on carnitine plasma concentrations in epileptic patients.
Topics: Adult; Ammonia; Carnitine; Epilepsy; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
[Pellagra in anticonvulsive therapy].
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Intellectual Disability; Pellagra; Phenytoin; Photosensitivity Disorders; Valproic Acid; Vitamins | 1990 |
The effects of phenytoin and carbamazepine on serum concentrations of mono-unsaturated metabolites of valproic acid.
Topics: Adult; Aged; Biotransformation; Carbamazepine; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1990 |
Induction of postaxial forelimb ectrodactyly with anticonvulsant agents in A/J mice.
Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Dimethadione; Female; Fetal Death; Fetal Resorption; Forelimb; Maternal Mortality; Mice; Mice, Inbred A; Oxazoles; Phenytoin; Pregnancy; Valproic Acid | 1990 |
Depression, anxiety, and temporal lobe epilepsy. Laterality of focus and symptoms.
Topics: Adult; Analysis of Variance; Anxiety; Carbamazepine; Depression; Epilepsy, Temporal Lobe; Female; Functional Laterality; Humans; Male; Phenytoin; Seizures; Sex Factors; Valproic Acid | 1990 |
In vivo determination of valproate binding constants during sole and multi-drug therapy.
Topics: Binding, Competitive; Carbamazepine; Drug Therapy, Combination; Food; Humans; Phenytoin; Seizures; Valproic Acid | 1990 |
Fluctuations of unbound and total phenytoin concentrations during the day in epileptic patients on valproic acid comedication.
Topics: Adolescent; Adult; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Middle Aged; Phenytoin; Protein Binding; Valproic Acid | 1990 |
[Clinical use of pharmacologic monitoring at a hospital community].
Topics: Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Utilization; Humans; Phenobarbital; Phenytoin; Product Surveillance, Postmarketing; Spain; Theophylline; Valproic Acid | 1990 |
Anticonvulsant therapy increases fentanyl requirements during anaesthesia for craniotomy.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Anticonvulsants; Carbamazepine; Craniotomy; Drug Interactions; Epilepsy; Fentanyl; Humans; Middle Aged; Phenytoin; Primidone; Valproic Acid | 1990 |
In vitro screening for anticonvulsant-induced teratogenesis in neural primary cultures and cell lines.
Topics: Animals; Anticonvulsants; Benzodiazepines; Cell Division; Cell Line; Cells, Cultured; Cerebral Cortex; Mice; Phenytoin; Teratogens; Valproic Acid | 1990 |
Eyelid twitching seizures and generalized tonic-clonic convulsions: a syndrome of idiopathic generalized epilepsy.
Topics: Acetazolamide; Adult; Epilepsy; Eyelid Diseases; Female; Humans; Phenytoin; Spasm; Valproic Acid | 1990 |
Carbamazepine metabolism in humans: effect of concurrent anticonvulsant therapy.
Topics: Administration, Oral; Adolescent; Adult; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Half-Life; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Valproic Acid | 1990 |
The inhibitory effect of anticonvulsants on human sperm motility: measured with a trans-membrane migration method.
Topics: Adult; Anticonvulsants; Carbamazepine; Cell Membrane; Depression, Chemical; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sperm Motility; Valproic Acid | 1990 |
Simultaneous determination of six antiepileptic drugs by capillary gas chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Hydroxides; Phenobarbital; Phenytoin; Potassium; Potassium Compounds; Primidone; Valproic Acid | 1990 |
Effects of polytherapy with phenytoin, carbamazepine, and stiripentol on formation of 4-ene-valproate, a hepatotoxic metabolite of valproic acid.
Topics: Adult; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dioxolanes; Dioxoles; Drug Interactions; Enzyme Activation; Fatty Acids, Monounsaturated; Female; Humans; Liver; Male; Phenytoin; Valproic Acid | 1990 |
Evoked potentials of self-interrupted Jacksonian epilepsy.
Topics: Aged; Electroencephalography; Epilepsies, Partial; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Evoked Potentials, Visual; Female; Humans; Mechanoreceptors; Neurologic Examination; Phenytoin; Physical Stimulation; Valproic Acid | 1990 |
Treatment of epilepsy in people with multiple handicap.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Disabled Persons; Epilepsy; Humans; Phenytoin; Valproic Acid | 1990 |
Neocerebellar hypoplasia in a neonate following intra-uterine exposure to anticonvulsants.
Topics: Abnormalities, Drug-Induced; Cerebellum; Drug Therapy, Combination; Epilepsy; Female; Humans; Nerve Degeneration; Neurons; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 1990 |
Rapid anti-epileptic drug assay.
Topics: Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Humans; Patient Compliance; Phenobarbital; Phenytoin; Valproic Acid | 1990 |
Selective response to carbamazepine in a case of organic mood disorder.
Topics: Aged; Carbamazepine; Depressive Disorder; Female; Humans; Neurocognitive Disorders; Phenobarbital; Phenytoin; Valproic Acid | 1990 |
[Valproic acid and stupor].
Topics: Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Male; Middle Aged; Phenytoin; Unconsciousness; Valproic Acid | 1990 |
Sensorineural hearing loss: a reversible effect of valproic acid.
Topics: Aged; Audiometry; Epilepsy, Temporal Lobe; Hearing Loss, Sensorineural; Humans; Male; Phenobarbital; Phenytoin; Remission, Spontaneous; Valproic Acid | 1990 |
Development of monoclonal antibodies for therapeutic drug monitoring.
Topics: Antibodies, Monoclonal; Anticonvulsants; Carbamazepine; Cross Reactions; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1990 |
Effects of age and antiepileptic drugs on plasma levels and kinetics of clobazam and N-desmethylclobazam.
Topics: Adolescent; Adult; Age Factors; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Child; Child, Preschool; Clobazam; Drug Therapy, Combination; Epilepsy; Humans; Infant; Phenobarbital; Phenytoin; Time Factors; Valproic Acid | 1990 |
Postmortem serum protein binding and brain concentrations of antiepileptic drugs in autoptic specimens from 45 epileptic patients.
Topics: Anticonvulsants; Blood Proteins; Brain; Carbamazepine; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Protein Binding; Valproic Acid | 1990 |
Cognitive function in adult epileptic patients established on anticonvulsant monotherapy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cognition; Epilepsy; Female; Humans; Intelligence; Male; Middle Aged; Osmolar Concentration; Phenytoin; Psychomotor Performance; Valproic Acid | 1990 |
Analysis of the factors influencing anti-epileptic drug concentrations--carbamazepine.
Topics: Aging; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Phenobarbital; Phenytoin; Regression Analysis; Retrospective Studies; Valproic Acid | 1990 |
Analysis of the factors influencing anti-epileptic drug concentrations--valproic acid.
Topics: Adolescent; Adult; Aging; Aspartate Aminotransferases; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Regression Analysis; Retrospective Studies; Sex Factors; Valproic Acid | 1990 |
Anticonvulsant drug mechanisms of action.
Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Clonazepam; Electroshock; gamma-Aminobutyric Acid; Humans; Ion Channels; Membrane Potentials; Mice; Neurons; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1985 |
Valproic acid and phenytoin effects on serum proteins and immunoglobulins of epileptic patients.
Topics: Adolescent; Adult; Aged; Alpha-Globulins; Beta-Globulins; Blood Proteins; Child; Child, Preschool; Epilepsy; Humans; Immunoglobulins; Infant; Middle Aged; Phenytoin; Serum Albumin; Valproic Acid | 1985 |
Evoked metabolic responses in the limbic-striate system produced by stimulation of anterior thalamic nucleus in man.
Topics: Adult; Brain; Carbamazepine; Electric Stimulation Therapy; Epilepsy, Temporal Lobe; Female; Glucose; Humans; Hydrocortisone; Limbic System; Male; Phenytoin; Radionuclide Imaging; Thalamic Nuclei; Valproic Acid | 1987 |
Anticonvulsants modify inactivation but not activation processes of sodium channels in Myxicola axons.
Topics: Animals; Anticonvulsants; Axons; Bepridil; Ion Channels; Phenytoin; Polychaeta; Pronase; Pyrrolidines; Sodium; Valproic Acid | 1987 |
Drugs for epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Epilepsy; Humans; Phenytoin; Valproic Acid | 1989 |
Serum aspirin-esterase activity in epileptic patients receiving treatment with phenobarbital, phenytoin, carbamazepine and valproic acid.
Topics: Adult; Anticonvulsants; Aspirin; Carbamazepine; Epilepsy; Esterases; Female; Humans; Male; Phenobarbital; Phenytoin; Valproic Acid | 1989 |
Derivation and evaluation of an equation for prediction of free phenytoin concentration in patients co-medicated with valproic acid.
Topics: Adult; Aged; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Mathematics; Middle Aged; Phenytoin; Retrospective Studies; Valproic Acid | 1989 |
Acute intermittent porphyria in two patients on anticonvulsant therapy and with normal erythrocyte porphobilinogen deaminase activity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Ammonia-Lyases; Anticonvulsants; Erythrocytes; Female; Humans; Hydroxymethylbilane Synthase; Male; Middle Aged; Phenytoin; Porphobilinogen; Porphyrias; Valproic Acid | 1989 |
Valproic acid, unlike other anticonvulsants, has no effect on methadone metabolism: two cases.
Topics: Adult; Drug Therapy, Combination; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Phenytoin; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1989 |
[Plasma determination of 7 common drugs by high performance liquid chromatography].
Topics: Anticonvulsants; Bronchodilator Agents; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Phenobarbital; Phenytoin; Theophylline; Valproic Acid | 1989 |
Carnitine deficiency associated with anticonvulsant therapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Carnitine; Cerebral Palsy; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1989 |
Effect of phenytoin, carbamazepine, and valproic acid on caffeine metabolism.
Topics: Adolescent; Adult; Aged; Antipyrine; Caffeine; Carbamazepine; Cytochrome P-450 Enzyme System; Enzyme Induction; Epilepsy; Female; Half-Life; Humans; Hydrocortisone; Male; Middle Aged; Phenytoin; Valproic Acid | 1989 |
Thyroid hormone concentrations in epileptic patients.
Topics: Anticonvulsants; Carbamazepine; Drug Combinations; Epilepsy; Humans; Phenytoin; Thyrotropin; Thyroxine; Triiodothyronine; Valproic Acid | 1989 |
[Effects of anticonvulsants on cellular immunity].
Topics: Animals; Anticonvulsants; Cell Division; Cytotoxicity, Immunologic; Female; Immunity, Cellular; Interleukin-2; Killer Cells, Natural; Lymphocyte Activation; Lymphocytes; Mice; Phenobarbital; Phenytoin; Recombinant Proteins; T-Lymphocytes, Cytotoxic; Valproic Acid | 1989 |
Unbound phenytoin plasma concentrations in patients comedicated with sodium valproate--the predictive value of plasma albumin concentration.
Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Phenytoin; Predictive Value of Tests; Protein Binding; Serum Albumin; Valproic Acid | 1989 |
Variations in protein binding of drugs in plasma and serum.
Topics: Anticonvulsants; Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Fluoroimmunoassay; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Protein Binding; Theophylline; Valproic Acid | 1989 |
Effects of anticonvulsants on plasma levels and entero-hepatic circulation of valproic acid and on hepatic drug metabolizing enzyme activities in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Enterohepatic Circulation; Liver; Male; Phenobarbital; Phenytoin; Protein Binding; Rats; Rats, Inbred Strains; Valproic Acid | 1989 |
Serum free levels and evaluation anticonvulsant drug interactions.
Topics: Adult; Anticonvulsants; Drug Interactions; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Valproic Acid | 1989 |
Probable pseudocholinesterase induction by valproic acid, carbamazepine and phenytoin leading to increased serum aspirin-esterase activity in epileptics.
Topics: Adolescent; Adult; Analysis of Variance; Carbamazepine; Carboxylic Ester Hydrolases; Cholinesterases; Enzyme Induction; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1989 |
Effects of anticonvulsants on spontaneous epileptiform activity which develops in the absence of chemical synaptic transmission in hippocampal slices.
Topics: Animals; Anticonvulsants; Benzodiazepines; Carbamazepine; Cell Membrane Permeability; Epilepsy; Hippocampus; In Vitro Techniques; Ion Channels; Midazolam; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1985 |
[Mechanism of action of antiepileptic drugs].
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; gamma-Aminobutyric Acid; Ion Exchange; Phenobarbital; Phenytoin; Receptors, Neurotransmitter; Synaptic Transmission; Valproic Acid | 1987 |
Automated determination of drugs in serum by liquid chromatography with column-switching. I. Separation of antiepileptic drugs and metabolites.
Topics: Acetonitriles; Anticonvulsants; Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Perchlorates; Phenobarbital; Phenytoin; Quality Control; Regression Analysis; Statistics as Topic; Trichloroacetic Acid; Valproic Acid | 1988 |
Differential effects of anticonvulsants on developing neurons in vitro.
Topics: Animals; Anticonvulsants; Binding, Competitive; Carbamazepine; Cells, Cultured; Chick Embryo; Immunohistochemistry; Neurons; Phenobarbital; Phenytoin; Receptors, Cell Surface; Receptors, Nerve Growth Factor; Valproic Acid | 1988 |
Etifoxine: evaluation of its anticonvulsant profile in mice in comparison with sodium valproate, phenytoin and clobazam.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Electroshock; Lethal Dose 50; Male; Mice; Oxazines; Phenytoin; Postural Balance; Seizures; Valproic Acid | 1985 |
Effects of anticonvulsant drugs on brain cultures from chick embryos: a comparison with cultures from embryos treated in ovo.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Brain; Carbonic Anhydrases; Cells, Cultured; Chick Embryo; Choline O-Acetyltransferase; gamma-Aminobutyric Acid; Kinetics; Neurons; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
Relationship between ossification and body weight of the CD-1 mouse fetus exposed in utero to anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Female; Fetus; Mice; Osteogenesis; Phenytoin; Pregnancy; Teratogens; Valproic Acid | 1986 |
Gastritis with valproate therapy.
Topics: Adolescent; Antacids; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Gastrins; Gastritis; Histamine H2 Antagonists; Humans; Male; Phenytoin; Valproic Acid | 1988 |
Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Chlorpromazine; Diazepam; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Male; Phenobarbital; Phenytoin; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1986 |
Nursing interventions for anticonvulsant drug interactions.
Topics: Anticonvulsants; Biotransformation; Carbamazepine; Drug Interactions; Humans; Nursing Care; Patient Education as Topic; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1986 |
The effects of valproate and phenytoin on the cAMP and cGMP levels in nervous tissue.
Topics: Action Potentials; Animals; Astacoidea; Brain; Brain Chemistry; Cyclic AMP; Cyclic GMP; Membrane Potentials; Nerve Tissue; Phenytoin; Spinal Cord; Valproic Acid | 1985 |
[The correlation between concentrations of anticonvulsive drugs in the brain and various parameters of maximal electroshock seizures in mice].
Topics: Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Drug Evaluation, Preclinical; Electroshock; Humans; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1986 |
Carbamazepine, phenytoin and sodium valproate monotherapy.
Topics: Carbamazepine; Epilepsy; Humans; Phenytoin; Valproic Acid | 1986 |
Chronic effects of ethosuximide, phenytoin, clonazepam, and valproic acid on the delayed-matching-to-sample performance of pigeons.
Topics: Animals; Anticonvulsants; Clonazepam; Columbidae; Ethosuximide; Phenytoin; Psychomotor Performance; Time Factors; Valproic Acid | 1986 |
Therapeutic drug monitoring in patients with chronic renal failure: evaluation of the Abbott TDx drug assay system.
Topics: Carbamazepine; Cross Reactions; Digoxin; Gentamicins; Humans; Immunoassay; Kidney Failure, Chronic; Lidocaine; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Valproic Acid; Vancomycin | 1986 |
Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture.
Topics: Action Potentials; Animals; Carbamazepine; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Ethosuximide; gamma-Aminobutyric Acid; Magnesium; Mice; Neurons; Phenytoin; Seizures; Sodium; Spinal Cord; Valproic Acid | 1986 |
Competition between valproate & phenytoin for plasma protein binding.
Topics: Binding, Competitive; Humans; Phenytoin; Serum Albumin; Valproic Acid | 1986 |
Phenylethylmalonamide serum levels in patients treated with primidone and the effects of other antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Malonates; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Valproic Acid | 1986 |
Modulation of the behavioral effects of anticonvulsant drugs by an external discriminative stimulus in the pigeon.
Topics: Animals; Anticonvulsants; Columbidae; Conditioning, Operant; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Phenobarbital; Phenytoin; Probability; Reinforcement Schedule; Valproic Acid | 1986 |
Chronic effects of clonazepam, phenytoin, ethosuximide, and valproic acid on learning in pigeons as assayed by a repeated acquisition procedure.
Topics: Animals; Benzodiazepinones; Clonazepam; Columbidae; Dose-Response Relationship, Drug; Drug Tolerance; Ethosuximide; Learning; Phenytoin; Valproic Acid | 1986 |
Drugs for epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Epilepsy; Humans; Phenytoin; Status Epilepticus; Valproic Acid | 1986 |
A comparative study of the relative influence of different anticonvulsant drugs, UV exposure and diet on vitamin D and calcium metabolism in out-patients with epilepsy.
Topics: Adult; Calcium; Carbamazepine; Diet; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Ultraviolet Rays; Valproic Acid; Vitamin D | 1986 |
[Various matters concerning the improvement of therapeutic tactics in epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Mental Disorders; Middle Aged; Phenytoin; Psychotropic Drugs; Valproic Acid | 1986 |
Genetic differences in anticonvulsant sensitivity in mouse lines selectively bred for ethanol withdrawal severity.
Topics: Alcohol Withdrawal Delirium; Alcohols; Animals; Anticonvulsants; Diazepam; Disease Susceptibility; Electroshock; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Psychoses, Alcoholic; Valproic Acid | 1986 |
Effects of anticonvulsant drugs on substantia nigra pars reticulata neurons.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Ethosuximide; Male; Neurons; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Substantia Nigra; Trimethadione; Valproic Acid | 1986 |
Memory disturbances in epileptic patients.
Topics: Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Memory Disorders; Phenytoin; Valproic Acid | 1986 |
Synergistic effects of oxiracetam and piracetam in combination with antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Drug Synergism; Drug Therapy, Combination; Epilepsy; Male; Phenobarbital; Phenytoin; Piracetam; Pyrrolidines; Pyrrolidinones; Rats; Valproic Acid | 1986 |
Lack of hepatotoxic interaction between the anticonvulsant drugs phenytoin, sodium valproate and phenobarbital in the rat.
Topics: Administration, Oral; Animals; Drug Interactions; Enzyme Induction; Liver; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Valproic Acid | 1986 |
Effects of phenobarbital in combination with phenytoin or valproic acid on the delayed-matching-to-sample performance of pigeons.
Topics: Animals; Columbidae; Drug Interactions; Memory, Short-Term; Phenobarbital; Phenytoin; Valproic Acid | 1986 |
Inhibition of quisqualate-induced seizures by glutamic acid diethyl ester and anti-epileptic drugs.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Carbamazepine; Diazepam; Female; Glutamates; Mice; Oxadiazoles; Phenobarbital; Phenytoin; Quisqualic Acid; Seizures; Valproic Acid | 1986 |
Long-term anticonvulsant therapy and vitamin D metabolism in ambulatory pubertal children.
Topics: Adolescent; Anticonvulsants; Calcifediol; Calcitriol; Calcium; Carbamazepine; Child; Drug Therapy, Combination; Female; Humans; Male; Phenytoin; Rickets; Seasons; Valproic Acid | 1986 |
Chronic valproic acid and coantiepileptic drug therapy and incidence of increases in serum liver enzymes.
Topics: Adolescent; Adult; Alanine Transaminase; Anticonvulsants; Aspartate Aminotransferases; Child; Child, Preschool; Drug Interactions; Female; Humans; Infant; Liver; Male; Phenobarbital; Phenytoin; Valproic Acid | 1986 |
[Combination of hydantoins and valproate. Evidence of its teratogenic effect in 4 consecutive gestations].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Child, Preschool; Drug Therapy, Combination; Female; Foot Deformities, Congenital; Humans; Infant; Male; Orofaciodigital Syndromes; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Valproic Acid | 1986 |
Barbiturate-refractory epilepsy: safe schedule for therapeutic substitution.
Topics: Adolescent; Adult; Anticonvulsants; Barbiturates; Carbamazepine; Drug Tolerance; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Prospective Studies; Valproic Acid | 1986 |
Anticonvulsant drugs in monotherapy. Effect on the fetus.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fetal Growth Retardation; France; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Italy; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Sweden; Valproic Acid | 1987 |
[Cognitive effects of antiepileptic drugs].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cognition Disorders; Epilepsy; Humans; Memory Disorders; Phenobarbital; Phenytoin; Temporal Lobe; Valproic Acid | 1987 |
Anticonvulsant medication in a mental handicap hospital: 1972-1982.
Topics: Anticonvulsants; Carbamazepine; Female; Hospitals, Psychiatric; Humans; Intellectual Disability; Male; Phenobarbital; Phenytoin; Valproic Acid | 1987 |
The effects of valproate on plasma concentration of phenytoin in normal and D-galactosamine-treated rats.
Topics: Animals; Galactosamine; In Vitro Techniques; Male; Phenytoin; Rats; Rats, Inbred Strains; Valproic Acid | 1987 |
Serum protein binding of phenytoin and valproic acid in insulin-dependent diabetes mellitus.
Topics: Adolescent; Adult; Blood Proteins; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glycosylation; Humans; Male; Middle Aged; Phenytoin; Serum Albumin; Valproic Acid | 1987 |
Inhibition of cartilage growth by the anticonvulsant drugs diphenylhydantoin and sodium valproate.
Topics: Animals; Cartilage, Articular; Cell Count; Male; Parathyroid Hormone; Phenytoin; Rats; Rats, Inbred Strains; Valproic Acid | 1988 |
An interaction between cytostatic and anticonvulsant drugs.
Topics: Adenocarcinoma, Papillary; Adult; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carbamazepine; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Interactions; Epilepsy; Female; Humans; Ovarian Neoplasms; Phenytoin; Valproic Acid | 1988 |
The effective evaluation of thyroid status in patients on phenytoin, carbamazepine or sodium valproate attending an epilepsy clinic.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Valproic Acid | 1987 |
The use of single sample clearance estimates to probe hepatic drug metabolism in rats. I.
Topics: Animals; Antipyrine; Liver; Male; Metabolic Clearance Rate; Mixed Function Oxygenases; Models, Biological; Pharmaceutical Preparations; Phenytoin; Rats; Rats, Inbred Strains; Theophylline; Valproic Acid; Warfarin | 1988 |
Delayed bone development in epileptic children assessed by microdensitometer.
Topics: Adolescent; Anticonvulsants; Bone Development; Calcifediol; Calcitriol; Child; Child, Preschool; Densitometry; Epilepsy; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Radiography; Valproic Acid | 1988 |
Cytochrome P-450-catalyzed desaturation of valproic acid in vitro. Species differences, induction effects, and mechanistic studies.
Topics: Animals; Carbamazepine; Cytochrome P-450 Enzyme System; Deuterium; Enzyme Induction; Fatty Acids, Monounsaturated; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Phenobarbital; Phenytoin; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Valproic Acid | 1988 |
A comparative study of the relative effects of anticonvulsant drugs and dietary folate on the red cell folate status of patients with epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Diet; Drug Therapy, Combination; Epilepsy; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Phenytoin; Valproic Acid | 1987 |
[Pharmacokinetic results of some antiepileptics].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1988 |
Antiepileptic drugs reduce serum uric acid.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Male; Phenytoin; Sex Factors; Uric Acid; Valproic Acid | 1987 |
The role of ultrasound in the early diagnosis of fetal structural defects following maternal anticonvulsant therapy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Diazepam; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Middle Aged; Phenobarbital; Phenytoin; Pregnancy; Prenatal Diagnosis; Prospective Studies; Ultrasonography; Valproic Acid | 1988 |
Pharmacologic interactions between valproate and other drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1988 |
Predictability of unbound antiepileptic drug concentrations in children treated with valproic acid and phenytoin.
Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Phenytoin; Protein Binding; Valproic Acid | 1988 |
Variability of phenytoin, carbamazepine and valproate concentrations in a clinic population.
Topics: Carbamazepine; Epilepsy; Female; Humans; Male; Minnesota; Outpatient Clinics, Hospital; Patient Compliance; Phenytoin; Valproic Acid | 1988 |
[Clinical treatment of resistant epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Resistance; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Patient Compliance; Phenytoin; Prognosis; Valproic Acid | 1988 |
Changes in clearance of sodium valproate with changes in dose.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1987 |
Effects of pregnancy on seizure threshold and the disposition and efficacy of antiepileptic drugs in the mouse.
Topics: Animals; Anticonvulsants; Carbamazepine; Electroshock; Female; Kinetics; Mice; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Seizures; Time Factors; Valproic Acid | 1985 |
Cutaneous manifestations of zinc deficiency during treatment with anticonvulsants.
Topics: Adult; Anticonvulsants; Female; Humans; Male; Phenytoin; Skin Diseases; Valproic Acid; Zinc | 1985 |
Effect of stimulus intensity on the profile of anticonvulsant activity of phenytoin, ethosuximide and valproate.
Topics: Animals; Anticonvulsants; Bicuculline; Electroshock; Ethosuximide; Male; Mice; Pentylenetetrazole; Phenytoin; Picrotoxin; Seizures; Valproic Acid | 1985 |
Time-dependent interaction between phenytoin and valproic acid.
Topics: Adolescent; Adult; Child; Child, Preschool; Circadian Rhythm; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1985 |
Effects of phenytoin, phenobarbital, and valproic acid, alone and in selected combinations, on schedule-controlled behavior of rats.
Topics: Animals; Conditioning, Operant; Drug Interactions; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Reinforcement Schedule; Time Factors; Valproic Acid | 1985 |
Antiepileptic drug evaluation in a new animal model: spontaneous petit mal epilepsy in the rat.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Ethosuximide; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Trimethadione; Valproic Acid | 1985 |
[Acute liver necrosis caused by valproate].
Topics: Adult; Creatine Kinase; Epilepsy; Female; Humans; Liver Cirrhosis; Phenytoin; Transaminases; Valproic Acid | 1985 |
Effects of pregnancy on antiepileptic drug utilization.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Epilepsy; Female; Humans; Kinetics; Metabolic Clearance Rate; Patient Compliance; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Valproic Acid | 1985 |
Adaptation of hepatic ammonia metabolism after chronic valproate administration in epileptics treated with phenytoin.
Topics: Adaptation, Physiological; Adult; Ammonia; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Kidney; Liver; Middle Aged; Phenytoin; Valproic Acid | 1985 |
Effect of different doses of valproic acid on the serum levels of total and free diphenylhydantoin.
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Phenytoin; Prospective Studies; Seizures; Valproic Acid | 1985 |
Anticonvulsant drugs and the genetically epilepsy-prone rat.
Topics: Acoustic Stimulation; Amitriptyline; Animals; Anticonvulsants; Carbamazepine; Desipramine; Disease Models, Animal; Epilepsy; Ethosuximide; Imipramine; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1985 |
Concurrent determination of valproic acid with other antiepileptic drugs by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1985 |
The effects of phenytoin and sodium valproate on the periodontal health of adult epileptic patients.
Topics: Adolescent; Adult; Aged; Alveolar Process; Bone Resorption; Cross-Sectional Studies; Dental Plaque Index; Epilepsy; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; Oral Hygiene; Periodontal Diseases; Periodontal Index; Phenytoin; Valproic Acid | 1985 |
Drug compliance and seizure control in epileptic children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Patient Compliance; Phenytoin; Valproic Acid | 1985 |
Effect of associated antiepileptic treatment on valproate-induced hyperammonemia.
Topics: Adolescent; Adult; Ammonia; Anticonvulsants; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Time Factors; Valproic Acid | 1985 |
Monotherapy and polytherapy for intractable epilepsies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1985 |
Effects of phenobarbital, clonazepam, valproic acid, ethosuximide, and phenytoin on the delayed matching-to-sample performance of pigeons.
Topics: Animals; Anticonvulsants; Clonazepam; Columbidae; Conditioning, Psychological; Dose-Response Relationship, Drug; Ethosuximide; Memory; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
Interictal EEG prediction of response to antiepileptic drug monotherapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prognosis; Sleep Deprivation; Valproic Acid | 1985 |
Evaluation of the effects of antiepileptic drugs on sleep-wakefulness patterns following 1 night total sleep deprivation in epileptic patients.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Humans; Middle Aged; Phenytoin; Sleep; Sleep Deprivation; Valproic Acid | 1985 |
American Academy of Pediatrics. Behavioral and cognitive effects of anticonvulsant therapy. Committee on Drugs.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Child; Child Behavior Disorders; Clonazepam; Cognition; Humans; Infant; Memory Disorders; Phenobarbital; Phenytoin; Psychological Tests; Valproic Acid | 1985 |
Chronic valproic acid therapy and incidence of increases in venous plasma ammonia.
Topics: Adolescent; Adult; Aged; Ammonia; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
The optimum use of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
Where, why, and what type of therapy.
Topics: Carbamazepine; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Recurrence; Risk; Succinimides; Valproic Acid | 1985 |
Monitoring: the most important role of the pediatrician.
Topics: Activities of Daily Living; Anticonvulsants; Carbamazepine; Child, Preschool; Environmental Monitoring; Epilepsy; Ethosuximide; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Referral and Consultation; Social Support; Valproic Acid | 1985 |
Serum concentrations of valproic acid: influence of dose and comedication.
Topics: Adolescent; Adult; Body Weight; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Valproic Acid | 1985 |
Seizure control following administration of anticonvulsant drugs in the quaking mouse.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Ethosuximide; Mice; Mice, Inbred C57BL; Mice, Quaking; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1985 |
Use of total and free anticonvulsant serum levels in clinical practice.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
Phenytoin interacts with calcium channels in brain membranes.
Topics: Animals; Brain; Calcium; Carbamazepine; Clonazepam; In Vitro Techniques; Ion Channels; Male; Nifedipine; Nitrendipine; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1984 |
Diphenylhydantoin substrate induced difference spectra: inhibition by other anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Ethosuximide; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Spectrophotometry; Thiazines; Valproic Acid | 1980 |
Psychiatric implications of anticonvulsant drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
[Effects of drug interaction in infancy (author's transl)].
Topics: Carbamazepine; Child; Chloramphenicol; Clonazepam; Dexamethasone; Drug Interactions; Humans; Isoniazid; Metronidazole; Phenobarbital; Phenytoin; Sulfonamides; Valproic Acid | 1980 |
Changes in regional brain levels of amino acid putative neurotransmitters after prolonged treatment with the anticonvulsant drugs diphenylhydantoin, phenobarbitone, sodium valproate, ethosuximide, and sulthiame in the rat.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Ethosuximide; gamma-Aminobutyric Acid; Glutamates; Male; Neurotransmitter Agents; Organ Specificity; Phenobarbital; Phenytoin; Rats; Taurine; Thiazines; Valproic Acid | 1981 |
[Anticonvulsant action of di-N-propylacetate combined with benzodiazepines, phenobarbital and phenytoin].
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Diazepam; Drug Therapy, Combination; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Semicarbazides; Valproic Acid | 1981 |
Choice of anticonvulsants in epilepsy.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Epilepsy; Ethosuximide; Follow-Up Studies; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
Effect of antiepileptic drugs on the cerebral amino acid uptake in vitro.
Topics: Absorption; Amino Acids; Animals; Anticonvulsants; Brain; Clonazepam; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Neurotransmitter Agents; Phenobarbital; Phenytoin; Valproic Acid | 1981 |
Mechanisms of action of antiepileptic drugs.
Topics: Acetazolamide; Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Chemical Phenomena; Chemistry; Humans; Paraldehyde; Phenytoin; Primidone; Seizures; Succinimides; Trimethadione; Valproic Acid | 1982 |
The influence of antiepileptic drugs on the electroencephalogram: a review of controlled clinical studies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
[Rise in gamma-GT during anticonvulsive therapy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
Effect of acetazolamide on the anticonvulsant potency of several antiepileptic drugs in mice.
Topics: Acetazolamide; Animals; Anticonvulsants; Barbital; Barbiturates; Brain; Drug Interactions; Male; Mephobarbital; Mice; Phenytoin; Time Factors; Trimethadione; Valproic Acid | 1983 |
Effect of hyperthermia on a thalamocortical system in the kitten and the cat: a preliminary study.
Topics: Animals; Cats; Cerebral Cortex; Fever; Phenytoin; Seizures, Febrile; Thalamus; Valproic Acid | 1983 |
Metabolic interactions of phenytoin in the rat: effect of coadministration with the anticonvulsant drugs sodium valproate, sulthiame, ethosuximide or phenobarbital.
Topics: Animals; Anticonvulsants; Brain; Drug Interactions; Ethosuximide; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Thiazines; Valproic Acid | 1984 |
Pharmacokinetics of antiepileptic drugs.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Ethosuximide; Female; Half-Life; Humans; Infant; Infant, Newborn; Intestinal Absorption; Kinetics; Male; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Valproic Acid | 1983 |
Pharmacodynamic factors in the occurrence of psychiatric symptoms among patients with epilepsy.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Epilepsy; Folic Acid; Humans; Kinetics; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid; Vitamin B 12 | 1983 |
Hepatotoxicity of sodium valproate.
Topics: Adolescent; Adult; Aged; Carbamazepine; Chemical and Drug Induced Liver Injury; Child; Fibrinogen; gamma-Glutamyltransferase; Humans; Middle Aged; Phenytoin; Prospective Studies; Retrospective Studies; Valproic Acid | 1983 |
Plasma concentrations of valproate during maintenance therapy in epileptic children.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Female; Half-Life; Humans; Male; Phenobarbital; Phenytoin; Valproic Acid | 1982 |
Therapeutic aspects of kinesiogenic paroxysmal choreoathetosis and familial paroxysmal choreoathetosis of the Mount and Reback type.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Athetosis; Carbamazepine; Child; Chorea; Female; Haloperidol; Humans; Male; Middle Aged; Motor Activity; Pedigree; Phenytoin; Primidone; Valproic Acid | 1983 |
Plasma arginine vasopressin concentrations in epileptics under monotherapy.
Topics: Adult; Anticonvulsants; Arginine Vasopressin; Carbamazepine; Epilepsy; Humans; Phenytoin; Primidone; Valproic Acid | 1983 |
Antiepileptic agents affect hypothalamic beta-endorphin concentrations.
Topics: Animals; Anticonvulsants; beta-Endorphin; Endorphins; Ethosuximide; Hypothalamus; Kinetics; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Somatostatin; Substance P; Valproic Acid | 1984 |
[Treatment of rapid nodding "salaam" spasms in childhood].
Topics: Adrenocorticotropic Hormone; Child, Preschool; Clonazepam; Electroencephalography; Female; Humans; Infant; Infant, Newborn; Male; Nitrazepam; Phenytoin; Primidone; Psychomotor Disorders; Spasms, Infantile; Valproic Acid | 1980 |
Calcium-dependent proteolysis in neural tissue is activated at physiologic intracellular Ca2+ levels and inhibited by some anticonvulsants.
Topics: Animals; Anticonvulsants; Astacoidea; Brain; Calcium; Calpain; Caprylates; Endopeptidases; Pentobarbital; Phenytoin; Protease Inhibitors; Spinal Cord; Valproic Acid | 1983 |
The treatable epilepsies.
Topics: Adrenocorticotropic Hormone; Child; Epilepsy; Humans; Phenytoin; Spasms, Infantile; Valproic Acid | 1983 |
A monkey model for status epilepticus: carbamazepine and valproate compared to three standard anticonvulsants.
Topics: Aluminum Hydroxide; Animals; Anticonvulsants; Carbamazepine; Diazepam; Macaca mulatta; Male; Phenobarbital; Phenytoin; Pyridoxine; Status Epilepticus; Valproic Acid | 1983 |
Clinical pharmacokinetics of drugs used in the treatment of status epilepticus.
Topics: Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Female; Humans; Kinetics; Models, Biological; Phenytoin; Pregnancy; Saimiri; Status Epilepticus; Valproic Acid | 1983 |
Teratogenic effects of valproic acid and diphenylhydantoin on mouse embryos in culture.
Topics: Animals; Culture Media; Embryo, Mammalian; Female; Mice; Mice, Inbred ICR; Organ Culture Techniques; Phenytoin; Pregnancy; Teratogens; Valproic Acid | 1983 |
Reduction of two-drug therapy in intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Clonazepam; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Prospective Studies; Valproic Acid | 1983 |
Febrile seizures in epileptic chicks: the effects of phenobarbital, phenytoin and valproate.
Topics: Animals; Chickens; Disease Models, Animal; Phenobarbital; Phenytoin; Reaction Time; Seizures, Febrile; Valproic Acid | 1983 |
A survey of non-barbiturate anticonvulsant drug overdose reported to the Poisons Information Service (UK).
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; Humans; Infant; Male; Phenytoin; Poison Control Centers; United Kingdom; Valproic Acid | 1983 |
Tonic status epilepticus presenting as confusional state.
Topics: Adolescent; Cognition Disorders; Confusion; Diazepam; Electroencephalography; Humans; Male; Methylphenidate; Phenobarbital; Phenytoin; Sleep; Status Epilepticus; Valproic Acid | 1983 |
Therapeutic monitoring of serum antiepileptic drug levels.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Laboratories; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid | 1983 |
Antiepileptic drugs and teratogenesis. How should patients, doctors and health authorities be counselled?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newborn; Oxazoles; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Risk; Trimethadione; Valproic Acid | 1983 |
Delayed effects of drug exposure during pregnancy: reproductive function.
Topics: Animals; Anticonvulsants; Estrus; Female; Fertility; Luteinizing Hormone; Male; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Reproduction; Sexual Maturation; Testosterone; Valproic Acid | 1983 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Humans; Phenobarbital; Phenytoin; Status Epilepticus; Valproic Acid | 1983 |
Treatment of the nonconvulsive epilepsies.
Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1983 |
Antiepileptic drug therapy. Fine tuning the dosage regimen.
Topics: Anticonvulsants; Carbamazepine; Drug Administration Schedule; Drug Interactions; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Valproic Acid | 1983 |
Serum and plasma for total and free anticonvulsant drug analyses: effects on EMIT assays and ultrafiltration devices.
Topics: Anticonvulsants; Carbamazepine; Humans; Immunoenzyme Techniques; Phenytoin; Plasma; Ultrafiltration; Valproic Acid | 1983 |
[Pharmacotherapy of epilepsy--current problems and controversies].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Seizures, Febrile; Status Epilepticus; Valproic Acid | 1983 |
Should we routinely measure free plasma phenytoin concentration?
Topics: Adolescent; Adult; Aged; Blood Proteins; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Protein Binding; Valproic Acid | 1984 |
Some clinical and EEG aspects of benign juvenile myoclonic epilepsy.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Drug Combinations; Electroencephalography; Epilepsies, Myoclonic; Ethosuximide; Female; Humans; Male; Phenytoin; Valproic Acid | 1984 |
Effects of anticonvulsants on hyperthermia-induced seizures in the rat pup.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Temperature; Differential Threshold; Disease Models, Animal; Electroencephalography; Phenobarbital; Phenytoin; Rats; Seizures, Febrile; Valproic Acid | 1984 |
[Determination of plasma levels of anticonvulsant drugs. Preliminary report of our experiences].
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Clonazepam; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1983 |
Unnecessary polypharmacy in patients with frequent seizures.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Free level monitoring of antiepileptic drugs. Clinical usefulness and case studies.
Topics: Adult; Anticonvulsants; Blood Proteins; Carbamazepine; Drug Interactions; Female; Humans; Male; Phenylbutazone; Phenytoin; Protein Binding; Serum Albumin; Valproic Acid | 1984 |
Anticonvulsant potency of common antiepileptic drugs in the gerbil.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Ethosuximide; Female; Gerbillinae; Male; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1983 |
Hepatic toxicity of antiepileptic drugs: a review.
Topics: Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Energy Metabolism; Epilepsy; Humans; Phenytoin; Valproic Acid | 1983 |
Microscale ultrafiltration technique for determining free drug in 50-microL serum samples.
Topics: Animals; Chloramphenicol; Diazepam; Furosemide; Humans; Indomethacin; Infant; Infant, Newborn; Microchemistry; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Ultrafiltration; Valproic Acid | 1984 |
Definition and implications of dose-dependent kinetics in clinical medicine.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Ethanol; Humans; Kinetics; Lidocaine; Pharmaceutical Preparations; Phenytoin; Valproic Acid | 1983 |
Effect of anticonvulsant drugs on thalamo-cortical and hippocampo-cortical self-sustained after-discharges in the rat.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Electric Stimulation; Electroencephalography; Epilepsy; Ethosuximide; Hippocampus; Kindling, Neurologic; Male; Phenytoin; Rats; Rats, Inbred Strains; Thalamus; Valproic Acid | 1984 |
Phenytoin intoxication as the first symptom of fatal liver damage induced by sodium valproate.
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Phenytoin; Protein Binding; Valproic Acid | 1984 |
Effects of some anticonvulsant drugs on brain GABA level and GAD and GABA-T activities.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Oxidoreductases; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
Enzyme induction in neonates after fetal exposure to antiepileptic drugs.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Anticonvulsants; Breath Tests; Carbamazepine; Carbon Radioisotopes; Enzyme Induction; Female; Humans; Infant, Newborn; Liver; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1983 |
The effects of various antiepileptic drugs on E-shock-induced amnesia in mice: dissociability of effects on convulsions and effects on memory.
Topics: Amnesia; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Electroshock; Ethosuximide; Humans; Male; Mice; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
Summing up of the success so far gained through choice of drugs or combinations of drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Cognition Disorders; Drug Therapy, Combination; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Psychotropic Drugs; Valproic Acid | 1984 |
Effect of valproate on free plasma phenytoin concentrations.
Topics: Adult; Binding, Competitive; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Protein Binding; Saliva; Serum Albumin; Valproic Acid | 1984 |
Effects of anticonvulsants on learning: performance of pigeons under a repeated acquisition procedure when exposed to phenobarbital, clonazepam, valproic acid, ethosuximide and phenytoin.
Topics: Animals; Anticonvulsants; Clonazepam; Columbidae; Dose-Response Relationship, Drug; Ethosuximide; Learning; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
[The incidence of postoperative epilepsy and prophylactic anticonvulsants in patients with intracranial aneurysm].
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Phenobarbital; Phenytoin; Postoperative Complications; Valproic Acid | 1984 |
Congenital liver damage after treatment of mother with valproic acid and phenytoin?
Topics: Adult; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Liver; Liver Diseases; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 1984 |
Nonsedative regimens in the treatment of epilepsy.
Topics: Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenytoin; Seizures; Valproic Acid | 1983 |
A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients.
Topics: Anticonvulsants; Antipyrine; Carbamazepine; Enzyme Induction; Epilepsy; Female; Glucaric Acid; Half-Life; Humans; Immunoenzyme Techniques; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Pharmacologic therapy of seizures in the elderly.
Topics: Aged; Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Status Epilepticus; Valproic Acid | 1984 |
[Plasma levels of antiepileptic agents in the treatment of epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Electrically elicited seizures from the inferior colliculus: a potential site for the genesis of epilepsy?
Topics: Animals; Chlordiazepoxide; Electric Stimulation; Electrophysiology; Epilepsy; Inferior Colliculi; Male; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1984 |
Teratogenic effects of dosage levels and time of administration of carbamazepine, sodium valproate, and diphenylhydantoin on craniofacial development in the CD-1 mouse fetus.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Face; Female; Gestational Age; Maternal-Fetal Exchange; Mice; Phenytoin; Pregnancy; Skull; Teratogens; Valproic Acid | 1984 |
Anticonvulsant effects on the memory performance of epileptics.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Intelligence; Memory; Memory Disorders; Middle Aged; Phenytoin; Valproic Acid | 1984 |
Anticonvulsants, folic acid and memory dysfunction in epileptics.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Erythrocytes; Folic Acid; Humans; Memory Disorders; Middle Aged; Phenytoin; Valproic Acid | 1984 |
One drug for childhood grand mal: medical audit for three-year remissions.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Glycine potentiates the action of some anticonvulsant drugs in some seizure models.
Topics: 3-Mercaptopropionic Acid; Acoustic Stimulation; Animals; Anticonvulsants; Disease Models, Animal; Drug Synergism; Glycine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1984 |
[Anticonvulsive combined therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
Valproic acid.
Topics: Adult; Drug Therapy, Combination; Humans; Male; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1980 |
The treatment of "shooting" pain.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Female; Humans; Male; Middle Aged; Pain; Phenytoin; Valproic Acid | 1980 |
Variable in vivo binding of valproic acid in epilepsy patients being medicated with other anticonvulsants.
Topics: Binding, Competitive; Epilepsy; Humans; Phenytoin; Serum Albumin; Valproic Acid | 1980 |
Therapeutic alternatives in phenytoin-induced gingival hyperplasia. A case report and discussion.
Topics: Adolescent; Epilepsy; Female; Gingival Hyperplasia; Humans; Phenytoin; Primidone; Valproic Acid | 1980 |
Binding of drugs to human serum albumin. XIV. The theoretical basis for the interaction between phenytoin and valproate.
Topics: Adolescent; Binding, Competitive; Blood Proteins; Child; Epilepsy; Humans; Phenytoin; Protein Binding; Serum Albumin; Valproic Acid | 1980 |
Interactions of valproic acid with phenytoin.
Topics: Adult; Drug Interactions; Half-Life; Humans; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Valproic Acid | 1980 |
Interaction between phenytoin and valproate.
Topics: Blood Proteins; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Protein Binding; Valproic Acid | 1980 |
Interaction between phenytoin and valproic acid: plasma protein binding and metabolic effects.
Topics: Adult; Blood Proteins; Drug Interactions; Humans; Kinetics; Male; Metabolic Clearance Rate; Phenytoin; Protein Binding; Saliva; Valproic Acid | 1980 |
Hepatotoxicity of sodium valproate and other anticonvulsants in rat hepatocyte cultures.
Topics: Animals; Anticonvulsants; Clonazepam; Culture Techniques; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Liver; Phenobarbital; Phenytoin; Primidone; Rats; Valproic Acid | 1980 |
[Coincidence of epilepsy and psychosis in a 16-year old female patient (author's transl)].
Topics: Adolescent; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Phenytoin; Valproic Acid | 1980 |
[Problems of therapeutic service in primidone therapy].
Topics: Adolescent; Drug Administration Schedule; Drug Interactions; Epilepsy, Tonic-Clonic; Female; Half-Life; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
[Termination of status epilepticus with sodium valproate].
Topics: Clonazepam; Diazepam; Humans; Infant; Phenytoin; Status Epilepticus; Valproic Acid | 1980 |
Pharmacokinetics of anticonvulsant drugs.
Topics: Anticonvulsants; Binding, Competitive; Brain; Carbamazepine; Drug Interactions; Drug Tolerance; Epilepsy; Folic Acid; Humans; Kinetics; Phenobarbital; Phenytoin; Protein Binding; Tissue Distribution; Valproic Acid | 1980 |
Drug interactions in epilepsy.
Topics: Anticonvulsants; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Humans; Isoniazid; Phenytoin; Valproic Acid | 1980 |
Teratogenic effects of anticonvulsants.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Cleft Palate; Eyelid Diseases; Female; Humans; Mice; Palate; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 1981 |
Phenytoin--valproic acid interaction in rhesus monkey.
Topics: Animals; Drug Interactions; In Vitro Techniques; Macaca mulatta; Male; Metabolic Clearance Rate; Phenytoin; Protein Binding; Valproic Acid | 1981 |
Effect of anticonvulsant drugs on inhibitory and excitatory pathways.
Topics: Animals; Carbamazepine; Cats; Electric Stimulation; Ethosuximide; Maxillary Nerve; Neural Pathways; Phenytoin; Time Factors; Valproic Acid | 1981 |
Interaction between phenytoin, 5-(p-hydroxyphenyl)-5-phenylhydantoin and valproate in the rat.
Topics: Animals; Blood Proteins; Drug Interactions; Kinetics; Metabolic Clearance Rate; Phenytoin; Protein Binding; Rats; Valproic Acid | 1981 |
Pharmacologic advances in seizure control.
Topics: Anticonvulsants; Carbamazepine; Child; Clonazepam; Humans; Kinetics; Phenytoin; Seizures; Status Epilepticus; Valproic Acid | 1981 |
Dissociation between free and bound phenytoin levels in presence of valproate sodium.
Topics: Adult; Drug Interactions; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Phenytoin; Saliva; Seizures; Valproic Acid | 1981 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1981 |
Effect of sodium dipropylacetate on conflict behavior in rats.
Topics: Animals; Conflict, Psychological; Diazepam; Male; Phenytoin; Punishment; Rats; Reward; Valproic Acid | 1980 |
[Daily fluctuations of plasma diphenylhydantoin in patients treated with diphenylhydantoin and sodium valproate].
Topics: Adult; Circadian Rhythm; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Valproic Acid | 1981 |
Altered drug binding to serum proteins in pregnant women: therapeutic relevance.
Topics: Adult; Blood Proteins; Diazepam; Female; Humans; In Vitro Techniques; Phenytoin; Pregnancy; Pregnancy Trimester, Third; Protein Binding; Valproic Acid | 1981 |
Reduction of steady-state valproate levels by other antiepileptic drugs.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Interactions; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1981 |
Quantitative evaluation of anticonvulsant effects on penicillin-induced spike foci in cats.
Topics: Animals; Anticonvulsants; Carbamazepine; Cats; Electroencephalography; Ethosuximide; Penicillins; Phenytoin; Seizures; Valproic Acid | 1981 |
[Daily plasma fluctuations of diphenylhydantoin in patients treated with diphenylhydantoin and sodium valproate].
Topics: Adult; Epilepsy; Humans; Phenytoin; Time Factors; Valproic Acid | 1981 |
Recent advances in the treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Valproic Acid | 1980 |
Only certain anticonvulsants protect against kainate neurotoxicity.
Topics: Animals; Anticonvulsants; Diazepam; Kainic Acid; Male; Nervous System Diseases; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1981 |
Delirium induced by the competitive interaction between phenytoin and dipropylacetate.
Topics: Adult; Binding, Competitive; Delirium; Drug Interactions; Humans; Male; Phenytoin; Seizures; Valproic Acid | 1981 |
Depression of axonal excitability by valproate is antagonized by phenytoin.
Topics: Action Potentials; Animals; Astacoidea; Axons; Dose-Response Relationship, Drug; In Vitro Techniques; Neural Conduction; Phenytoin; Valproic Acid | 1981 |
How valproate and phenytoin affect the ionic conductances and active transport characteristics of the crayfish giant axon.
Topics: Action Potentials; Animals; Astacoidea; Axons; Biological Transport, Active; Chlorides; In Vitro Techniques; Phenytoin; Potassium; Sodium; Valproic Acid | 1981 |
Phenytoin-valproate interaction: importance of saliva monitoring in epilepsy.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Protein Binding; Saliva; Valproic Acid | 1982 |
Daily fluctuations of dipropylacetate (DPA) serum level in epileptic patients.
Topics: Adolescent; Adult; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Primidone; Time Factors; Valproic Acid | 1980 |
Effects of sodium valproate on the serum protein binding of phenytoin, and on liver enzyme activity.
Topics: Antipyrine; Aspartate Aminotransferases; Blood Proteins; Glucaric Acid; Half-Life; Humans; Liver; Phenytoin; Protein Binding; Time Factors; Valproic Acid | 1980 |
Serial free and plasma valproic acid and phenytoin monitoring and drug interactions.
Topics: Adolescent; Adult; Circadian Rhythm; Drug Interactions; Epilepsy; Female; Humans; Male; Phenytoin; Valproic Acid | 1981 |
Anticonvulsant drugs used in the treatment of lancinating pain. A comparison.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Female; Humans; Male; Middle Aged; Pain; Phenytoin; Valproic Acid | 1981 |
Drugs in the treatment of tinnitus.
Topics: Amobarbital; Antidepressive Agents, Tricyclic; Carbamazepine; Ethanol; Humans; Lidocaine; Phenytoin; Primidone; Tinnitus; Valproic Acid | 1981 |
Plasma levels and pharmacokinetics of antipileptic drugs in children.
Topics: Adolescent; Age Factors; Anticonvulsants; Biological Availability; Biotransformation; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy; Humans; Kinetics; Metabolic Clearance Rate; Phenytoin; Valproic Acid | 1981 |
Some behavioral effects of antiepileptic drugs during acute and prolonged treatment in the rat.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Tolerance; Motor Skills; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1981 |
Diurnal oscillations in plasma protein binding of valproic acid.
Topics: Adolescent; Adult; Blood Proteins; Circadian Rhythm; Epilepsy; Fatty Acids, Nonesterified; Female; Humans; Male; Phenytoin; Protein Binding; Valproic Acid | 1982 |
Stuporous episodes during treatment with sodium valproate: report of seven cases.
Topics: Anticonvulsants; Cognition Disorders; Consciousness Disorders; Electroencephalography; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Valproic Acid | 1982 |
Effect of anticonvulsant drugs on kainic acid-induced epileptiform activity.
Topics: Animals; Anticonvulsants; Diazepam; Electroencephalography; Ethosuximide; Guinea Pigs; Hippocampus; Kainic Acid; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1982 |
Monitoring free valproic acid in epilepsy patients medicated with coanticonvulsants.
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenytoin; Valproic Acid | 1982 |
The effects of anticonvulsants on memory function in epileptic patients: preliminary findings.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Memory; Memory, Short-Term; Mental Recall; Phenytoin; Valproic Acid | 1981 |
Placental transfer of anticonvulsants (phenobarbital, phenytoin, valproic acid) and the elimination from neonates.
Topics: Anticonvulsants; Bilirubin; Female; Fetal Blood; Half-Life; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Valproic Acid | 1981 |
Brain maturation following administration of phenobarbital, phenytoin, and sodium valproate to developing rats or to their dams: effects on synthesis of brain myelin and other subcellular membrane proteins.
Topics: Animals; Anticonvulsants; Brain; Female; Intracellular Membranes; Membrane Proteins; Myelin Proteins; Organ Size; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Valproic Acid | 1982 |
The effect of anticonvulsant drugs on the development of male rats and their fertility.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Fertility; Genitalia, Male; Male; Phenytoin; Rats; Rats, Inbred Strains; Sperm Count; Sperm Motility; Valproic Acid | 1982 |
Antipyrine disposition in relation to lowered anticonvulsant plasma level during pregnancy.
Topics: Adult; Anticonvulsants; Antipyrine; Delivery, Obstetric; Dose-Response Relationship, Drug; Epilepsy; Female; Half-Life; Humans; Infant, Newborn; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Postpartum Period; Pregnancy; Pregnancy Complications; Time Factors; Valproic Acid | 1982 |
Fatal hepatic failure in a child treated with phenytoin and valproic acid.
Topics: Chemical and Drug Induced Liver Injury; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Female; Humans; Phenytoin; Valproic Acid | 1982 |
Therapeutic concentration of antiepileptic drugs and the severity of epileptogenesis.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Isoxazoles; Phenytoin; Valproic Acid; Zonisamide | 1982 |
EEG quantification of drug level effects in monkey model of partial epilepsy.
Topics: Animals; Anticonvulsants; Circadian Rhythm; Clonazepam; Disease Models, Animal; Electroencephalography; Kinetics; Macaca mulatta; Male; Phenobarbital; Phenytoin; Primidone; Seizures; Valproic Acid | 1982 |
Two antiepileptic drugs for intractable epilepsy with complex-partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
[A study on cerebrospinal fluid and saliva to serum concentration ratios of anticonvulsants--Phenytoin, Phenobarbital, Valproic Acid and Primidone in epileptic patients].
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Saliva; Valproic Acid | 1982 |
Reduced bone growth in rats treated with anticonvulsant drugs: a type II pseudohypoparathyroidism?
Topics: Animals; Anticonvulsants; Bone and Bones; Bone Development; Calcium; Female; Male; Parathyroid Glands; Parathyroid Hormone; Phenytoin; Pseudohypoparathyroidism; Rats; Rats, Inbred Strains; Thyroidectomy; Valproic Acid | 1982 |
Anticonvulsant activation of pain-suppressive systems.
Topics: Aldehyde Oxidoreductases; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Male; Neural Inhibition; Nociceptors; Periaqueductal Gray; Phenytoin; Rats; Rats, Inbred Strains; Succinate-Semialdehyde Dehydrogenase; Valproic Acid | 1982 |
Effect of single doses of sodium valproate on serum phenytoin levels and protein binding in epileptic patients.
Topics: Adult; Blood Proteins; Epilepsy; Humans; Kinetics; Male; Phenytoin; Protein Binding; Valproic Acid | 1980 |
Prediction of free levels of phenytoin and carbamazepine in patients comedicated with valproic acid.
Topics: Adult; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Humans; Phenytoin; Valproic Acid | 1995 |
Practical considerations in anticonvulsant therapy--Part 2.
Topics: Anticonvulsants; Benzodiazepines; Cost Control; Epilepsy; Ethosuximide; Humans; Monitoring, Physiologic; Patient Compliance; Patient Education as Topic; Pharmacists; Phenobarbital; Phenytoin; Primidone; Role; Valproic Acid | 1995 |
Case report: thyrotropin-releasing hormone-induced myoclonus and tremor in a patient with Hashimoto's encephalopathy.
Topics: Adult; Female; Humans; Menstrual Cycle; Myoclonus; Phenytoin; Prolactin; Thyroid Gland; Thyroiditis, Autoimmune; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Tremor; Valproic Acid | 1995 |
Agitated behavior relieved following treatment of cervical dystonia in dementia.
Topics: Alzheimer Disease; Botulinum Toxins; Chlorpromazine; Dystonia; Female; Humans; Isoxazoles; Middle Aged; Neck Muscles; Phenytoin; Piperidines; Risperidone; Valproic Acid | 1995 |
The clinical pharmacology of antiepileptic drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Humans; Phenobarbital; Phenytoin; Reference Values; Valproic Acid | 1995 |
Possible interaction between acyclovir and antiepileptic treatment.
Topics: Acyclovir; Biological Availability; Child; Drug Interactions; Humans; Male; Phenytoin; Valproic Acid | 1995 |
Anticonvulsant effect of intraventricular antiepileptic drugs. Experimental study.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Epilepsy; Injections, Intraventricular; Male; Midazolam; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Valproic Acid | 1995 |
Effect of antiepileptic drugs on absence-like seizures in the tremor rat.
Topics: Animals; Anticonvulsants; Data Interpretation, Statistical; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Injections, Intraperitoneal; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred WKY; Rats, Mutant Strains; Seizures; Time Factors; Trimethadione; Valproic Acid | 1995 |
Predicting unbound phenytoin concentrations in patients receiving valproic acid: a comparison of two prediction methods.
Topics: Adult; Bias; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Predictive Value of Tests; Retrospective Studies; Valproic Acid | 1995 |
Drugs for epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Valproic Acid | 1995 |
[Sensitive physiologic perceptual tests for ocular side effects of drugs exemplified by various anticonvulsants].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Color Perception; Contrast Sensitivity; Dark Adaptation; Epilepsy; Female; Flicker Fusion; Humans; Male; Phenytoin; Psychophysics; Retina; Sensory Thresholds; Valproic Acid; Visual Perception | 1995 |
Anticonvulsants suppress c-Fos protein expression in spinal cord neurons following noxious thermal stimulation.
Topics: Animals; Anticonvulsants; Carbamazepine; Hot Temperature; Male; Neurons; Phenytoin; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Valproic Acid | 1995 |
[Changes in drug therapy and in seizure frequency in an institution for epilepsy patients between 1971 and 1986].
Topics: Aged; Aged, 80 and over; Anticonvulsants; Barbiturates; Carbamazepine; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Female; Humans; Longitudinal Studies; Male; Middle Aged; Phenytoin; Retrospective Studies; Succinimides; Valproic Acid | 1994 |
The stability of anticonvulsant drugs in whole blood.
Topics: Anticonvulsants; Carbamazepine; Drug Stability; Drug Storage; Humans; Phenobarbital; Phenytoin; Temperature; Valproic Acid | 1994 |
Juvenile myoclonic epilepsy: diagnosis, management and outcome.
Topics: Adolescent; Adult; Alcohol Drinking; Anticonvulsants; Carbamazepine; Epilepsies, Myoclonic; Female; Humans; Lamotrigine; Life Style; Male; Middle Aged; Phenytoin; Prognosis; Sleep Deprivation; Stress, Physiological; Time Factors; Treatment Outcome; Triazines; Valproic Acid; Weight Gain | 1995 |
Effects of the peptide BCH-325 upon the efficacy of common antiepileptic drugs.
Topics: Amino Acid Sequence; Animals; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Peptide Fragments; Phenobarbital; Phenytoin; Seizures; Sodium Channels; Synaptic Transmission; Valproic Acid | 1994 |
Unilateral musical hallucinations and all that jazz.
Topics: Aged; Auditory Perceptual Disorders; Cerebrovascular Disorders; Dominance, Cerebral; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Hallucinations; Humans; Music; Neuropsychological Tests; Phenytoin; Presbycusis; Temporal Lobe; Valproic Acid | 1994 |
A comparative study of serum F protein and other liver function tests as an index of hepatocellular damage in epileptic patients.
Topics: Adult; Alkaline Phosphatase; Anticonvulsants; Aspartate Aminotransferases; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Female; gamma-Glutamyltransferase; Humans; Isoantigens; Liver Function Tests; Male; Middle Aged; Phenytoin; Valproic Acid | 1994 |
Antiepileptics in the elderly. Pharmacoepidemiology and pharmacokinetics.
Topics: Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Health Surveys; Homes for the Aged; Humans; Minnesota; Nursing Homes; Phenytoin; United States; Valproic Acid | 1994 |
Changes of thyroid hormone levels in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Phenytoin; Thyrotropin; Thyroxine; Triiodothyronine; Valproic Acid | 1994 |
Epilepsy treatment in The Netherlands. Comparison of matched groups of two medical centres.
Topics: Adolescent; Adult; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Female; gamma-Aminobutyric Acid; Humans; Male; Netherlands; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Statistics, Nonparametric; Treatment Outcome; Valproic Acid; Vigabatrin | 1994 |
[Antioxidative activity of drugs used in anticonvulsive therapy].
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Antioxidants; Benzodiazepines; Benzodiazepinones; In Vitro Techniques; Lipid Peroxidation; Models, Biological; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1993 |
Effects of the conventional anticonvulsants, phenytoin, carbamazepine, and valproic acid, on sodium-potassium-adenosine triphosphatase in acute ischemic brain.
Topics: Animals; Carbamazepine; Cerebral Cortex; Cerebral Infarction; Dose-Response Relationship, Drug; Male; Phenytoin; Premedication; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Valproic Acid | 1994 |
Disabling tremor after lamotrigine with sodium valproate.
Topics: Anticonvulsants; Drug Interactions; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Lamotrigine; Phenytoin; Tremor; Triazines; Valproic Acid | 1993 |
Pharmacodynamic interactions between phenytoin and valproate: individual and combined antiepileptic and neurotoxic actions in mice.
Topics: Animals; Brain; Brain Diseases; Drug Interactions; Drug Synergism; Electroshock; Epilepsy; Female; Mice; Phenytoin; Valproic Acid | 1994 |
Protein binding of digitoxin, valproate and phenytoin in sera from diabetics.
Topics: Adult; Blood Proteins; Diabetes Mellitus, Type 1; Digitoxin; Female; Humans; Male; Phenytoin; Protein Binding; Serum Albumin; Valproic Acid | 1993 |
Pregnancy, epilepsy, management and outcome: a 10-year perspective.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Birth Weight; Carbamazepine; Cohort Studies; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant, Newborn; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Risk Factors; Valproic Acid | 1993 |
Interaction between valproate and branched-chain amino acid metabolism.
Topics: Adult; Amino Acids, Branched-Chain; Carbamazepine; Drug Therapy, Combination; Female; Humans; Isoleucine; Male; Oxidation-Reduction; Phenytoin; Urine; Valproic Acid | 1994 |
Influence of aminophylline and 8-(p-sulfophenyl)theophylline on the anticonvulsive action of diphenylhydantoin, phenobarbital, and valproate against maximal electroshock-induced convulsions in mice.
Topics: Aminophylline; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Phenobarbital; Phenytoin; Seizures; Theophylline; Valproic Acid | 1993 |
Pharmacological characterization of phenytoin-resistant amygdala-kindled rats, a new model of drug-resistant partial epilepsy.
Topics: Amino Acids; Aminocaproates; Amygdala; Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Resistance; Electric Stimulation; Electrodes, Implanted; Epilepsies, Partial; Female; Kindling, Neurologic; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Valproic Acid; Vigabatrin | 1993 |
A new chronic model of spontaneous nonconvulsive generalized seizures.
Topics: 4-Butyrolactone; Animals; Cerebral Cortex; Corpus Callosum; Electroencephalography; Epilepsy, Absence; Epilepsy, Generalized; Ethosuximide; Evoked Potentials; Injections, Intraperitoneal; Male; Phenytoin; Rats; Rats, Wistar; Seizures; Sodium Oxybate; Valproic Acid | 1993 |
Pharmacokinetic interaction of zonisamide in rats. Effect of zonisamide on other antiepileptics.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Drug Interactions; Erythrocytes; In Vitro Techniques; Isoxazoles; Male; Phenobarbital; Phenytoin; Protein Binding; Rats; Rats, Wistar; Valproic Acid; Zonisamide | 1993 |
Dual effect of valproic acid on the pharmacokinetics of phenytoin.
Topics: Administration, Oral; Adult; Blood Proteins; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Humans; Male; Phenytoin; Valproic Acid | 1993 |
Five years of anticonvulsant monitoring on site at the epilepsy clinic.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; Outpatient Clinics, Hospital; Phenobarbital; Phenytoin; Prospective Studies; Scotland; Time Factors; Valproic Acid | 1993 |
An audit of therapeutic drug monitoring of anticonvulsants.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Drug Monitoring; Epilepsy; Humans; Medical Audit; Northern Ireland; Phenobarbital; Phenytoin; Valproic Acid | 1995 |
Low serum concentration of all-trans and 13-cis retinoic acids in patients treated with phenytoin, carbamazepine and valproate. Possible relation to teratogenicity.
Topics: Adult; Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Humans; Isotretinoin; Male; Middle Aged; Phenytoin; Teratogens; Tretinoin; Valproic Acid | 1995 |
A model for estimating individualized valproate clearance values in children.
Topics: Administration, Oral; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Male; Metabolic Clearance Rate; Models, Theoretical; Pharmacokinetics; Phenobarbital; Phenytoin; Valproic Acid | 1995 |
Pharmacology of cortical epileptic afterdischarges in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsies, Myoclonic; Epilepsy; Male; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Severity of Illness Index; Valproic Acid | 1996 |
Effect of valproate on cerebral metabolism and blood flow: an 18F-2-deoxyglucose and 15O water positron emission tomography study.
Topics: Adult; Brain; Carbamazepine; Cerebrovascular Circulation; Deoxyglucose; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Oxygen Radioisotopes; Phenobarbital; Phenytoin; Tomography, Emission-Computed; Valproic Acid; Water | 1996 |
Increasing-current electroshock seizure test: a new method for assessment of anti- and pro-convulsant activities of drugs in mice.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Carbamazepine; Convulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; Ear; Electrodes; Electroshock; Ethosuximide; Injections, Intravenous; Male; Mice; Morphine; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1996 |
[Study of the influence of anticonvulsant treatment on thyroid function].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Enzyme-Linked Immunosorbent Assay; Epilepsy; Female; Humans; Hypothyroidism; Male; Middle Aged; Phenobarbital; Phenytoin; Prospective Studies; Thyroid Gland; Thyroid Hormones; Thyrotropin; Valproic Acid | 1995 |
[Subependymal nodular heterotopia and epilepsy].
Topics: Age of Onset; Anticonvulsants; Brain; Choristoma; Epilepsy; Female; Humans; Middle Aged; Pedigree; Phenytoin; Sex Factors; Valproic Acid; X Chromosome | 1996 |
Vitamin K-dependent coagulopathy in a child receiving anticonvulsant therapy.
Topics: Adolescent; Anticonvulsants; Blood Coagulation; Drug Combinations; Factor X Deficiency; Female; Gingivectomy; Hemorrhage; Humans; Phenytoin; Prothrombin Time; Valproic Acid; Vitamin K | 1996 |
Lamotrigine potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Diazepam; Drug Synergism; Female; Lamotrigine; Male; Mice; Mice, Inbred DBA; Phenytoin; Seizures; Triazines; Valproic Acid | 1996 |
[Oligospermia improved by switching an anticonvulsant from phenytoin to valproate].
Topics: Adult; Anticonvulsants; Humans; Male; Oligospermia; Phenytoin; Valproic Acid | 1996 |
Differential effects of phenytoin and sodium valproate on seizure-induced changes in gamma-aminobutyric acid and glutamate release in vivo.
Topics: Animals; Anticonvulsants; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Phenytoin; Rats; Seizures; Valproic Acid | 1995 |
Clearance of phenytoin and valproic acid is affected by a small body weight reduction in an epileptic obese patient: a case study.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Half-Life; Humans; Metabolic Clearance Rate; Obesity; Phenobarbital; Phenytoin; Valproic Acid; Weight Loss | 1996 |
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid | 1996 |
The necessity of adjusting the dosage of zonisamide when coadministered with other anti-epileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Valproic Acid; Zonisamide | 1996 |
Salivary protein composition in epileptic patients on different medications.
Topics: Adult; Aged; Albumins; Amylases; Anticonvulsants; Carbamazepine; Cystatin C; Cystatins; Cysteine Proteinase Inhibitors; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Immunoglobulin A, Secretory; Male; Middle Aged; Phenytoin; Polypharmacy; Saliva; Salivary Cystatins; Salivary Proteins and Peptides; Secretory Rate; Valproic Acid | 1996 |
Valproate metabolites in high-dose valproate plus phenytoin therapy.
Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Humans; L-Lactate Dehydrogenase; Liver Diseases; Liver Function Tests; Oxidation-Reduction; Phenytoin; Valproic Acid | 1996 |
Effects of various valproic acid derivatives on low-calcium spontaneous epileptiform activity in hippocampal slices.
Topics: Animals; Anticonvulsants; Calcium; Carbohydrates; Electroshock; Epilepsy; Hippocampus; In Vitro Techniques; Male; Phenytoin; Pyramidal Cells; Rats; Rats, Wistar; Valproic Acid | 1995 |
Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 9; Diagnostic Errors; Electroencephalography; Epilepsy, Generalized; Ethosuximide; Female; Hodgkin Disease; Humans; Intellectual Disability; Lupus Erythematosus, Systemic; Magnetic Resonance Imaging; Myoclonus; Phenytoin; Pseudolymphoma; Trisomy; Valproic Acid | 1996 |
Influence of a potential anti-asthmatic drug, CR 2039, upon the anticonvulsive activity of conventional antiepileptics against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Asthma; Avoidance Learning; Benzamides; Bronchodilator Agents; Carbamazepine; Drug Interactions; Electroshock; Epilepsy, Tonic-Clonic; Male; Memory; Mice; Phenytoin; Psychomotor Performance; Tetrazoles; Valproic Acid | 1996 |
Population pharmacokinetics of felbamate in children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Drug Monitoring; Felbamate; Humans; Infant; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Seizures; Valproic Acid | 1997 |
Elevated free fatty acid concentrations in lipemic sera reduce protein binding of valproic acid significantly more than phenytoin.
Topics: Bilirubin; Blood Proteins; Charcoal; Creatinine; Fatty Acids, Nonesterified; Humans; Hyperlipidemias; Phenytoin; Protein Binding; Triglycerides; Urea; Valproic Acid | 1997 |
3-Hydroxymethylphenytoin valproic acid ester, a new prodrug combining two anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Convulsants; Electroshock; Mice; Pentylenetetrazole; Phenytoin; Prodrugs; Rats; Valproic Acid | 1996 |
Fixed drug eruption to three anticonvulsant drugs: an unusual case of polysensitivity.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Eruptions; Humans; Male; Phenytoin; Valproic Acid | 1997 |
The effects of anticonvulsant drugs on NMDA-EPSP, AMPA-EPSP, and GABA-IPSP in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; Male; N-Methylaspartate; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Valproic Acid | 1997 |
Influence of isradipine, niguldipine and dantrolene on the anticonvulsive action of conventional antiepileptics in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Carbamazepine; Dantrolene; Dihydropyridines; Disease Models, Animal; Drug Interactions; Electroshock; Epilepsy; Female; Isradipine; Lethal Dose 50; Mice; Motor Activity; Phenobarbital; Phenytoin; Random Allocation; Seizures; Valproic Acid | 1997 |
Color vision tests for early detection of antiepileptic drug toxicity.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Color Perception; Epilepsy; Humans; Osmolar Concentration; Phenytoin; Valproic Acid; Vision Disorders; Vision Tests | 1997 |
Topiramate for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Fructose; Humans; Phenytoin; Topiramate; Valproic Acid | 1997 |
Effects of valproate, phenytoin, and MK-801 in a novel model of epileptogenesis.
Topics: Animals; Anticonvulsants; Behavior, Animal; Brain Stem; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Epilepsy; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Flurothyl; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neural Pathways; Phenytoin; Valproic Acid | 1997 |
N6-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive activity of antiepileptic drugs.
Topics: Adenosine; Animals; Anticonvulsants; Body Temperature; Carbamazepine; Darkness; Drug Synergism; Electroshock; Female; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Purinergic P1 Receptor Agonists; Valproic Acid | 1997 |
AWD 140-190: a new anticonvulsant with a very good margin of safety.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Male; Mice; Morpholines; Phenytoin; Proline; Rats; Rats, Sprague-Dawley; Valproic Acid | 1997 |
Risk of serious cutaneous disorders after initiation of use of phenytoin, carbamazepine, or sodium valproate: a record linkage study.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Hypersensitivity; Female; Hospitalization; Humans; Male; Medical Records; Middle Aged; Phenytoin; Risk; Skin Diseases; Valproic Acid | 1997 |
Anticonvulsant usage is associated with an increased risk of procarbazine hypersensitivity reactions in patients with brain tumors.
Topics: Adult; Anticonvulsants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carbamazepine; Cohort Studies; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Procarbazine; Retrospective Studies; Valproic Acid | 1997 |
Elevated free phenytoin and free valproic acid concentrations in sera of patients infected with human immunodeficiency virus.
Topics: Anticonvulsants; Chemistry, Pharmaceutical; HIV Infections; Humans; Phenytoin; Polypharmacy; Seizures; Valproic Acid | 1998 |
Anticonvulsant drugs fail to modulate chemotherapy-induced cytotoxicity and growth inhibition of human malignant glioma cells.
Topics: Anticonvulsants; Antineoplastic Agents; Carbamazepine; Cell Division; Cell Survival; Glioma; Humans; Osmolar Concentration; Phenytoin; Tumor Cells, Cultured; Valproic Acid | 1998 |
Effect of nimodipine on the efficacy of commonly used antiepileptic drugs in rats.
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Drug Synergism; Electroshock; Female; Male; Nimodipine; Phenytoin; Rats; Seizures; Valproic Acid | 1998 |
Treatment of the epileptic patient in the dental office.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dental Care for Chronically Ill; Emergencies; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Humans; Liability, Legal; Male; Medical History Taking; Middle Aged; Patient Care Planning; Phenobarbital; Phenytoin; Valproic Acid | 1998 |
Effect of nimodipine on the cognitive dysfunction induced by phenytoin and valproate in rats.
Topics: Animals; Avoidance Learning; Female; Male; Memory Disorders; Nimodipine; Phenytoin; Rats; Retention, Psychology; Valproic Acid | 1997 |
Heart rate variability in patients with epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsies, Myoclonic; Epilepsy, Temporal Lobe; Female; Heart Rate; Humans; Male; Middle Aged; Phenytoin; Reference Values; Valproic Acid | 1998 |
[A case of anticonvulsive drug-induced liver injury accompanied by a transient appearance of antimitochondrial antibody, M2].
Topics: Aged; Anticonvulsants; Autoantibodies; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Diseases, Alcoholic; Mitochondria, Liver; Phenytoin; Valproic Acid | 1998 |
Electrophysiologic analysis of the actions of valproate on pyramidal neurons in the rat hippocampal slice.
Topics: Action Potentials; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Hippocampus; Neural Conduction; Phenytoin; Potassium; Pyramidal Cells; Rats; Rats, Wistar; Refractory Period, Electrophysiological; Sodium Channels; Temperature; Valproic Acid | 1998 |
Interictal cardiovascular autonomic responses in patients with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Autonomic Nervous System; Blood Pressure; Epilepsy; Female; Heart Rate; Humans; Male; Phenytoin; Reflex; Valproic Acid | 1998 |
The influence of L-NG-nitroarginine methyl ester, an inhibitor of nitric oxide synthase, upon the anticonvulsive activity of conventional antiepileptic drugs against maximal electroshock in mice.
Topics: Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Drug Antagonism; Electroshock; Enzyme Inhibitors; Female; Memory; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1998 |
Does antiepileptic therapy affect immune response?
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cytokines; Drug Therapy, Combination; Epilepsy; Felbamate; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Receptors, Interleukin-2; Triazines; Valproic Acid | 1998 |
New dosage forms for old anticonvulsants.
Topics: Anticonvulsants; Diazepam; Dosage Forms; Humans; Phenytoin; Valproic Acid | 1998 |
Effect of non-steroidal anti-inflammatory drugs on the anticonvulsive activity of valproate and diphenylhydantoin against maximal electroshock-induced seizures in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Drug Synergism; Electroshock; Male; Mice; Motor Activity; Phenytoin; Seizures; Valproic Acid | 1998 |
Peripheral benzodiazepine receptor expression on leukocytes and neutrophil function during anticonvulsant monotherapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Leukocytes; Lymphocytes; Male; Middle Aged; Neutrophils; Phenytoin; Receptors, GABA-A; Valproic Acid | 1998 |
Additive anticonvulsant effect of flunarizine and sodium valproate on electroshock and chemoshock induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Electroshock; Ethosuximide; Flunarizine; Male; Mice; Motor Activity; Pentylenetetrazole; Phenytoin; Seizures; Valproic Acid | 1998 |
Quantifying the costs of serious adverse drug reactions to antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Direct Service Costs; Drug Costs; Drug Hypersensitivity; Epilepsy; Female; Hospital Costs; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Ontario; Phenytoin; Retrospective Studies; Seizures; Valproic Acid | 1998 |
Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Biogenic Amines; Blood Platelets; Brain; Carbamazepine; Cyclohexanecarboxylic Acids; Dopamine; Dopamine Uptake Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium; Male; Norepinephrine; p-Chloroamphetamine; Phenytoin; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Syndrome; Synaptosomes; Tetrodotoxin; Triazines; Valproic Acid; Zonisamide | 1998 |
Pharmacodynamic interaction between phenytoin and sodium valproate changes seizure thresholds and pattern.
Topics: Analysis of Variance; Animals; Anticonvulsants; Drug Interactions; Male; Phenytoin; Rats; Rats, Wistar; Seizures; Valproic Acid | 1998 |
Comparison of total and free phenytoin serum concentrations measured by high-performance liquid chromatography and standard TDx assay: implications for the prediction of free phenytoin serum concentrations.
Topics: Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Fluorescence Polarization; Humans; In Vitro Techniques; Models, Theoretical; Phenytoin; Protein Binding; Valproic Acid | 1998 |
Carbamazepine-10,11-epoxide in therapeutic drug monitoring.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Drug Monitoring; Female; Fluorescence Polarization Immunoassay; Humans; Lamotrigine; Phenytoin; Sodium Channels; Triazines; Valproic Acid | 1998 |
[Serum lipids. lipoproteins, and apolipoproteins in adult epileptics treated with carbamazepine, valproic acid, or phenytoin].
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Apolipoproteins; Carbamazepine; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Enzyme Activation; Epilepsy; Female; Humans; Hyperlipidemias; Lipids; Lipoproteins; Male; Middle Aged; Phenytoin; Sex Characteristics; Triglycerides; Valproic Acid | 1998 |
[Drug-resistant epilepsy].
Topics: Adult; Anticonvulsants; Brain Neoplasms; Calcinosis; Carbamazepine; Diagnosis, Differential; Drug Resistance; Drug Therapy, Combination; Electroencephalography; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Glioma; Humans; Magnetic Resonance Imaging; Neoplasms, Germ Cell and Embryonal; Neoplasms, Neuroepithelial; Phenytoin; Temporal Lobe; Tomography, Emission-Computed, Single-Photon; Valproic Acid; Vigabatrin | 1998 |
Modelling of the pharmacodynamic interaction between phenytoin and sodium valproate.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Male; Phenytoin; Rats; Rats, Wistar; Valproic Acid | 1998 |
Elevated plasma concentrations of homocysteine in antiepileptic drug treatment.
Topics: Age Factors; Ambulatory Care; Anticonvulsants; Carbamazepine; Convulsants; Depression, Chemical; Epilepsy; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Pyridoxine; Risk Factors; Sex Factors; Valproic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 1999 |
Lamotrigine drug interactions in a TDM material.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Triazines; Valproic Acid | 1999 |
Assessment of colour vision in epileptic patients exposed to single-drug therapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Color Perception; Color Vision Defects; Diplopia; Epilepsy, Complex Partial; Female; Humans; Male; Middle Aged; Phenytoin; Severity of Illness Index; Single-Blind Method; Valproic Acid | 1999 |
Successful treatment with gabapentin in the presence of hypersensitivity syndrome to phenytoin and carbamazepine: a report of three cases.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Hypersensitivity; Drug Interactions; Epilepsy, Complex Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1999 |
Effect of heating human sera at a temperature necessary to deactivate human immunodeficiency virus on measurement of free phenytoin, free valproic acid, and free carbamazepine concentrations.
Topics: Anticonvulsants; Blood; Carbamazepine; Hemofiltration; HIV; Hot Temperature; Humans; Phenytoin; Valproic Acid; Virus Activation | 1999 |
Free drug measurements. When and why? An overview.
Topics: Biological Availability; Carbamazepine; Digoxin; Pharmaceutical Preparations; Pharmacokinetics; Phenytoin; Protein Binding; Temperature; Valproic Acid | 1999 |
Malformations in offspring of women with epilepsy: a prospective study.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Comorbidity; Congenital Abnormalities; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Gestational Age; Humans; Incidence; Infant, Newborn; Italy; Male; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Pregnancy Complications; Prospective Studies; Risk Factors; Valproic Acid | 1999 |
Clozapine-induced stuttering: epileptic brain activity?
Topics: Anticonvulsants; Antipsychotic Agents; Brain; Clozapine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Generalized; Female; Humans; Middle Aged; Phenytoin; Schizophrenia, Paranoid; Stuttering; Valproic Acid | 1999 |
Clinical experience with new antiepileptic drugs: antiepileptic drugs in Europe.
Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cross-Cultural Comparison; Drug Approval; Drug Monitoring; Drug Prescriptions; Epilepsy; Europe; History, 20th Century; Humans; Phenobarbital; Phenytoin; Polypharmacy; Valproic Acid | 1999 |
NMDA- but not kainate-mediated events reduce efficacy of some antiepileptic drugs against generalized tonic-clonic seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Epilepsy, Tonic-Clonic; Kainic Acid; Male; Mice; N-Methylaspartate; Phenobarbital; Phenytoin; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1999 |
Postoperative anticonvulsant prophylaxis for patients treated for cerebral aneurysms.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Craniotomy; Drug Administration Schedule; Epilepsy; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Male; Middle Aged; Phenytoin; Postoperative Complications; Valproic Acid | 1999 |
Epileptiform activity of veratridine model in rat brain slices: effects of antiepileptic drugs.
Topics: Action Potentials; Animals; Anticonvulsants; Convulsants; Ethosuximide; Hippocampus; Ion Channel Gating; Ion Transport; Phenytoin; Pyramidal Cells; Rats; Sodium; Sodium Channels; Valproic Acid; Veratridine | 2000 |
Blepharoptosis and central nervous system abnormalities in combined valproate and hydantoin embryopathy.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Blepharoptosis; Brain; Drug Therapy, Combination; Eyelids; Female; Humans; Infant; Magnetic Resonance Imaging; Male; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Valproic Acid | 2000 |
Possible analgesic effect of vigabatrin in animal experimental chronic neuropathic pain.
Topics: Analgesics; Animals; Anticonvulsants; Carbamazepine; Chronic Disease; Neuralgia; Phenytoin; Rats; Rats, Wistar; Valproic Acid; Vigabatrin | 1999 |
Blockade of neuronal sodium channels by the antiepileptic drugs phenytoin, carbamazepine and sodium valproate.
Topics: Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Membrane Potentials; Neurons; Oocytes; Patch-Clamp Techniques; Phenytoin; Sodium Channel Blockers; Sodium Channels; Valproic Acid; Xenopus laevis | 1999 |
Effects of standard anticonvulsant drugs on different patterns of epileptiform discharges induced by 4-aminopyridine in combined entorhinal cortex-hippocampal slices.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamazepine; Entorhinal Cortex; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Male; Pentobarbital; Phenobarbital; Phenytoin; Prohibitins; Rats; Rats, Wistar; Valproic Acid | 2000 |
Improved sexual function in three men taking lamotrigine for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Erectile Dysfunction; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sexual Dysfunctions, Psychological; Triazines; Valproic Acid | 2000 |
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenobarbital; Phenytoin; Primidone; Treatment Outcome; Valproic Acid; Vitamin B 12 | 2000 |
Cognitive dysfunction induced by phenytoin and valproate in rats: effect of nitric oxide.
Topics: Animals; Anticonvulsants; Arginine; Cognition Disorders; Enzyme Inhibitors; Female; Male; Memory; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Phenytoin; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1999 |
[Drug resistant epilepsy in Senegal: therapeutic, clinical and socioeconomic factors].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Resistance; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Senegal; Socioeconomic Factors; Valproic Acid | 1999 |
Incidence of intravenous site reactions in neurotrauma patients receiving valproate or phenytoin.
Topics: Adult; Aged; Anticonvulsants; Brain Injuries; Chi-Square Distribution; Double-Blind Method; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Pain; Phenytoin; Randomized Controlled Trials as Topic; Retrospective Studies; Valproic Acid | 2000 |
A clinical study of 57 children with fetal anticonvulsant syndromes.
Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Fetal Diseases; Humans; Infant; Male; Phenotype; Phenytoin; Pregnancy; Syndrome; Valproic Acid | 2000 |
Exceptionally long absence status: multifactorial etiology, drug interactions and complications.
Topics: Aged; Anticonvulsants; Brain Ischemia; Dementia, Vascular; Drug Interactions; Epilepsy, Generalized; Hernia, Inguinal; Humans; Male; Phenytoin; Postoperative Complications; Status Epilepticus; Valproic Acid | 1999 |
Phenytoin poisoning after using Chinese proprietary medicines.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Combinations; Drug Contamination; Drugs, Chinese Herbal; Female; Humans; Phenytoin; Valproic Acid | 2000 |
Influence of chronic barbiturate administration on sleep apnea after hypersomnia presentation: case study.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Disorders of Excessive Somnolence; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Humans; Phenytoin; Positive-Pressure Respiration; Seizures; Sleep Apnea, Obstructive; Valproic Acid | 2000 |
Effects of combined administration of zonisamide and valproic acid or phenytoin to nitric oxide production, monoamines and zonisamide concentrations in the brain of seizure-susceptible EL mice.
Topics: Animals; Anticonvulsants; Biogenic Monoamines; Brain; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Epilepsy; Isoxazoles; Mice; Mice, Mutant Strains; Nitric Oxide; Phenytoin; Valproic Acid; Zonisamide | 2000 |
Antiepileptic drug withdrawal in patients with temporal lobe epilepsy undergoing presurgical video-EEG monitoring.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Female; Hospital Units; Humans; Length of Stay; Male; Middle Aged; Monitoring, Physiologic; Phenytoin; Substance Withdrawal Syndrome; Valproic Acid; Videotape Recording | 2001 |
The teratogenicity of anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Case-Control Studies; Congenital Abnormalities; Epilepsy; Face; Female; Fetal Growth Retardation; Fingers; Humans; Infant, Newborn; Logistic Models; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2001 |
Heparin-induced release of protein-bound solutes during hemodialysis is an in vitro artifact.
Topics: Aged; Anticoagulants; Artifacts; Blood Proteins; Blood Specimen Collection; Chromatography, Gas; Chromatography, High Pressure Liquid; Citric Acid; Cresols; Enzyme Inhibitors; Fatty Acids, Nonesterified; Female; Hematologic Tests; Hemofiltration; Heparin; Humans; In Vitro Techniques; Lactones; Lipase; Male; Middle Aged; Orlistat; Palmitic Acid; Phenytoin; Protein Binding; Renal Dialysis; Valproic Acid | 2001 |
The concentration of three anti-seizure medications in hair: the effects of hair color, controlling for dose and age.
Topics: Age Factors; Anticonvulsants; Carbamazepine; Hair; Hair Color; Humans; Phenytoin; Valproic Acid | 2001 |
Antiepileptic drug therapy and its management in sudden unexpected death in epilepsy: a case-control study.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cohort Studies; Death, Sudden; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Registries; Regression Analysis; Risk; Risk Factors; Sweden; Valproic Acid | 2001 |
Epilepsy.
Topics: Anticonvulsants; Automobile Driving; Epilepsy; Female; Guidelines as Topic; Humans; Phenytoin; Valproic Acid | 2001 |
Are serum anticonvulsant levels in people with epilepsy appropriately monitored?
Topics: Anticonvulsants; Drug Monitoring; Epilepsy; Humans; Logistic Models; Phenytoin; Valproic Acid | 2001 |
[Analogs of generic preparations for the treatment of epilepsy: is their use safe?].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drugs, Generic; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Phenytoin; Therapeutic Equivalency; Valproic Acid | 2001 |
Comparison of the anticonvulsant efficacies and neurotoxic effects of valproic acid, phenytoin, and the ketogenic diet.
Topics: 3-Hydroxybutyric Acid; Animals; Anticonvulsants; Dietary Fats; Electroencephalography; Energy Intake; Male; Pentylenetetrazole; Phenytoin; Rats; Rats, Sprague-Dawley; Seizures; Treatment Outcome; Valproic Acid | 2001 |
[Treatment of febrile convulsions].
Topics: Age Factors; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Child, Preschool; Diazepam; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Seizures, Febrile; Time Factors; Valproic Acid | 2002 |
Preliminary evaluation of oral anticonvulsant treatment in the quinpirole model of bipolar disorder.
Topics: Administration, Oral; Animals; Anticonvulsants; Bipolar Disorder; Brain; Carbamazepine; Disease Models, Animal; Dopamine Agonists; Drug Administration Schedule; Fructose; Hyperkinesis; Motor Activity; Neurons; Phenytoin; Quinpirole; Rats; Receptors, Dopamine; Topiramate; Valproic Acid | 2002 |
Ophthalmic findings in fetal anticonvulsant syndrome(s).
Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Eye Abnormalities; Female; Fetal Diseases; Humans; Infant; Male; Phenytoin; Prevalence; Refractive Errors; Retrospective Studies; Strabismus; Syndrome; Valproic Acid; Visual Acuity | 2002 |
Evaluation of fluorescence polarization assays for measuring valproic acid, phenytoin, carbamazepine and phenobarbital in serum.
Topics: Anticonvulsants; Automation; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Fluorescence Polarization; Humans; Phenobarbital; Phenytoin; Reproducibility of Results; Valproic Acid | 2002 |
Performance characteristics of four immunoassays for antiepileptic drugs on the IMMULITE 2000 automated analyzer.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Cross Reactions; Drug Monitoring; Humans; Immunoassay; Phenobarbital; Phenytoin; Reproducibility of Results; Sensitivity and Specificity; Uremia; Valproic Acid | 2002 |
In vitro removal of therapeutic drugs with a novel adsorbent system.
Topics: Adsorption; Anti-Bacterial Agents; Biocompatible Materials; Carbamazepine; Digoxin; Glycopeptides; Hemoperfusion; Humans; Models, Biological; Phenobarbital; Phenytoin; Sorption Detoxification; Theophylline; Uremia; Valproic Acid | 2002 |
Antiepileptic drugs and agents that inhibit voltage-gated sodium channels prevent NMDA antagonist neurotoxicity.
Topics: Animals; Anticonvulsants; Carbamazepine; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Ion Channel Gating; Lamotrigine; Neurotransmitter Agents; Phenytoin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Triazines; Valproic Acid | 2002 |
Effect of seizures and antiepileptic drugs on prolactin secretions.
Topics: Adolescent; Adult; Anticonvulsants; Drug Therapy, Combination; Female; Humans; Male; Phenytoin; Prolactin; Seizures; Valproic Acid | 2002 |
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid | 2003 |
Ketamine for refractory status epilepticus: a case of possible ketamine-induced neurotoxicity.
Topics: Adult; Anticonvulsants; Atrophy; Brain; Electroencephalography; Excitatory Amino Acid Antagonists; Humans; Ketamine; Lorazepam; Magnetic Resonance Imaging; Male; Neurotoxicity Syndromes; Phenytoin; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Status Epilepticus; Valproic Acid | 2003 |
Therapeutic monitoring of digoxin and antiepileptic drugs in Egypt and Saudi Arabia.
Topics: Anticonvulsants; Carbamazepine; Cardiotonic Agents; Developing Countries; Digoxin; Drug Monitoring; Egypt; Humans; Phenytoin; Retrospective Studies; Saudi Arabia; Valproic Acid | 2003 |
Evaluation of therapeutic drug monitoring of antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Hospitals, Teaching; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Polypharmacy; Valproic Acid | 2003 |
Effects of valproate, phenytoin, and zonisamide on clonic and tonic seizures induced by acute and repeated exposure of mice to flurothyl.
Topics: Animals; Anticonvulsants; Brain Stem; Convulsants; Epilepsy, Tonic-Clonic; Flurothyl; Isoxazoles; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Phenytoin; Prosencephalon; Seizures; Time Factors; Valproic Acid; Zonisamide | 2003 |
Valproate overdose: a comparative cohort study of self poisonings.
Topics: Adult; Analysis of Variance; Anticonvulsants; Carbamazepine; Cohort Studies; Critical Care; Drug Overdose; Drug Prescriptions; Female; Humans; Male; New South Wales; Phenytoin; Prospective Studies; Valproic Acid | 2003 |
Topiramate protects against glutamate- and kainate-induced neurotoxicity in primary neuronal-astroglial cultures.
Topics: Animals; Animals, Newborn; Anticonvulsants; Astrocytes; Calcium; Calcium Signaling; Cell Membrane; Cell Survival; Cells, Cultured; Fructose; Glutamic Acid; Immunohistochemistry; Kainic Acid; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Phenytoin; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Topiramate; Valproic Acid | 2003 |
An assessment of the in vitro antimicrobial effects of two antiepileptic drugs--sodium valproate and phenytoin.
Topics: Anti-Bacterial Agents; Anticonvulsants; Bacteria; Culture Media; Microbial Sensitivity Tests; Microscopy, Fluorescence; Phenytoin; Valproic Acid; Yeasts | 2003 |
Valproate suppresses status epilepticus induced by 4-aminopyridine in CA1 hippocampus region.
Topics: 4-Aminopyridine; Animals; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Hippocampus; Injections; Male; Phenytoin; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid | 2003 |
Appropriateness of serum level determinations of antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Drug Monitoring; Female; Humans; Male; Middle Aged; Phenytoin; Retrospective Studies; Seizures; Valproic Acid | 2003 |
Interaction between anticonvulsants and human placental carnitine transporter.
Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techniques; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Models, Biological; Nipecotic Acids; Organic Cation Transport Proteins; Phenytoin; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Proteins; Solute Carrier Family 22 Member 5; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2004 |
Cost of epilepsy in patients attending a secondary-level hospital in India.
Topics: Anticonvulsants; Carbamazepine; Efficiency, Organizational; Epilepsy; Hospital Costs; Hospitalization; Humans; India; Phenobarbital; Phenytoin; Valproic Acid | 2004 |
The effect of long-term antiepileptic treatment on serum cholesterol (TC, HDL, LDL) and triglyceride levels in adult epileptic patients on monotherapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Triglycerides; Valproic Acid | 2004 |
Antiepileptic drugs inhibit cell growth in the human breast cancer cell line MCF7.
Topics: Anticonvulsants; Breast Neoplasms; Cell Division; Cell Line, Tumor; Drug Screening Assays, Antitumor; Estrogens; Female; Humans; Lamotrigine; Phenobarbital; Phenytoin; Protein Binding; Receptors, Estrogen; Triazines; Valproic Acid | 2004 |
Therapeutic doses of topiramate are not toxic to the developing rat brain.
Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Apoptosis; Brain; Dose-Response Relationship, Drug; Fructose; Neurons; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Topiramate; Valproic Acid | 2004 |
Population pharmacokinetic modeling of steady state clearance of carbamazepine and its epoxide metabolite from sparse routine clinical data.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Asian People; Body Weight; Carbamazepine; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Metabolic Clearance Rate; Methods; Models, Biological; Pharmacokinetics; Phenobarbital; Phenytoin; Regression Analysis; Valproic Acid | 2004 |
Activation of serum aminotransferases by pyridoxal-5' -phosphate in epileptic patients treated with anticonvulsant drugs.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Pyridoxal Phosphate; Sensitivity and Specificity; Transaminases; Valproic Acid | 2004 |
Effects of piracetam alone and in combination with antiepileptic drugs in rodent seizure models.
Topics: Action Potentials; Animals; Anticonvulsants; Brain; Cobalt; Disease Models, Animal; Drug Combinations; Drug Synergism; Electroshock; Epilepsy; Epilepsy, Absence; Hippocampus; Male; Mice; Mice, Inbred DBA; Neuroprotective Agents; Phenobarbital; Phenytoin; Piracetam; Valproic Acid | 2004 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Hypersensitivity; Ethosuximide; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lymphatic Diseases; Phenobarbital; Phenytoin; Syndrome; Triazines; Valproic Acid | 2004 |
The outcome of initiation of antiepileptic drug monotherapy in primary care: a UK database survey.
Topics: Aged; Anticonvulsants; Carbamazepine; Child, Preschool; Clinical Competence; Epilepsy; Family Practice; Female; Humans; Lamotrigine; Male; Phenytoin; Treatment Outcome; Triazines; Valproic Acid | 2004 |
Assessment of the epilepsy treatment gap in two cities of south-east of Brazil.
Topics: Adult; Anticonvulsants; Brazil; Carbamazepine; Epilepsy; Health Services Accessibility; Health Services Needs and Demand; Humans; Phenobarbital; Phenytoin; Prevalence; Valproic Acid | 2004 |
Longer term outcome of children born to mothers with epilepsy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intelligence; Multivariate Analysis; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Valproic Acid | 2004 |
Interactions between riluzole and conventional antiepileptic drugs -- a comparison of results obtained in the subthreshold method and isobolographic analysis.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Riluzole; Seizures; Valproic Acid | 2004 |
Influence of coadministered antiepileptic drugs on serum phenobarbital concentrations in epileptic patients: quantitative analysis based on a suitable transforming factor.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Combinations; Epilepsy; Female; Humans; Infant; Isoxazoles; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Valproic Acid; Zonisamide | 2004 |
[Influence of psychotropic drugs on thrombocytes aggregation in patients with epilepsy].
Topics: Adolescent; Adult; Barbiturates; Carbamazepine; Epilepsy; Humans; In Vitro Techniques; Lamotrigine; Middle Aged; Phenobarbital; Phenytoin; Platelet Aggregation; Psychotropic Drugs; Thrombocytopenia; Triazines; Valproic Acid | 2004 |
Video-EEG study in an adult and a child with eyelid myoclonia with absences.
Topics: Adult; Anticonvulsants; Child; Dominance, Cerebral; Drug Therapy, Combination; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Absence; Epilepsy, Reflex; Evoked Potentials; Female; Frontal Lobe; Humans; Lamotrigine; Male; Myoclonus; Phenytoin; Photic Stimulation; Sunlight; Triazines; Valproic Acid; Video Recording | 2004 |
Bone mass and turnover in women with epilepsy on antiepileptic drug monotherapy.
Topics: Adolescent; Adult; Anticonvulsants; Bone and Bones; Bone Remodeling; Carbamazepine; Epilepsy; Female; Humans; Minerals; Phenytoin; Premenopause; Valproic Acid | 2005 |
[Diminished antiepileptic drug serum levels during acyclovir treatment].
Topics: Acyclovir; Anticonvulsants; Child, Preschool; Drug Interactions; Encephalitis, Herpes Simplex; Humans; Male; Phenytoin; Valproic Acid | 2005 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics.
Topics: Anticonvulsants; Carbamazepine; Causality; Epilepsy; Germany; Humans; Incidence; Inpatients; Lamotrigine; Phenobarbital; Phenytoin; Prohibitins; Registries; Reproducibility of Results; Risk Assessment; Risk Factors; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2005 |
High vulnerability to acute dystonic reactions: a case of antipsychotic exposure and uncontrolled seizure activity.
Topics: Anticonvulsants; Antipsychotic Agents; Chronic Disease; Cytochrome P-450 CYP2D6; Dibenzothiazepines; Dystonia; Genotype; Humans; Male; Middle Aged; Phenytoin; Psychotic Disorders; Quetiapine Fumarate; Seizures; Valproic Acid | 2005 |
Fit for a fracture.
Topics: Anticonvulsants; Epilepsy; Ergocalciferols; Female; Femoral Neck Fractures; Follow-Up Studies; Fractures, Spontaneous; Humans; Mental Disorders; Middle Aged; Osteoporosis; Phenobarbital; Phenytoin; Treatment Outcome; Valproic Acid; Vitamin D; Vitamin D Deficiency | 2005 |
[Rickets. A rare complication of anti-epileptic treatments. Report of two cases in children].
Topics: Anticonvulsants; Black People; Calcifediol; Child; Contraindications; Drug Monitoring; Electroencephalography; Epilepsies, Myoclonic; Ergocalciferols; Ethosuximide; Humans; Male; Phenobarbital; Phenytoin; Radiography; Rare Diseases; Rickets; Valproic Acid | 1976 |
An investigation of the efficacy of mood stabilizers in rodent models of prepulse inhibition.
Topics: Amphetamine; Anesthetics, Dissociative; Animals; Antimanic Agents; Carbamazepine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Ketamine; Lithium; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phenytoin; Reflex, Startle; Valproic Acid | 2005 |
Phenytoin stimulates chondrogenic differentiation in mouse clonal chondrogenic EC cells, ATDC5.
Topics: 3T3 Cells; Aggrecans; Animals; Anticonvulsants; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Calcification, Physiologic; Cartilage; Cell Differentiation; Cell Line, Tumor; Chondrocytes; Chondrogenesis; Chondroitin Sulfate Proteoglycans; Clone Cells; Collagen Type II; Dose-Response Relationship, Drug; Extracellular Matrix Proteins; Gene Expression; Hedgehog Proteins; Lectins, C-Type; Mice; Parathyroid Hormone-Related Protein; Patched Receptors; Patched-1 Receptor; Phenobarbital; Phenytoin; Proteins; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Trans-Activators; Valproic Acid | 2005 |
Pregabalin drug interaction studies: lack of effect on the pharmacokinetics of carbamazepine, phenytoin, lamotrigine, and valproate in patients with partial epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Pregabalin; Triazines; Valproic Acid | 2005 |
1-Methyl-1,2,3,4-tetrahydroisoquinoline enhances the anticonvulsant action of carbamazepine and valproate in the mouse maximal electroshock seizure model.
Topics: Animals; Anticonvulsants; Carbamazepine; Dopamine Antagonists; Dyskinesia, Drug-Induced; Electroshock; Male; Mice; Neurotoxicity Syndromes; Phenytoin; Tetrahydroisoquinolines; Valproic Acid | 2006 |
An experimental evaluation of anticonvulsant activity of Vitex-negundo.
Topics: Animals; Anticonvulsants; Drug Combinations; Drug Evaluation, Preclinical; Drug Interactions; Electroshock; Male; Pentylenetetrazole; Phenytoin; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats; Rats, Wistar; Reference Standards; Seizures; Valproic Acid; Vitex | 2005 |
Improvement of oligoasthenozoospermia in epileptic patients on switching anti-epilepsy medication from sodium valproate to phenytoin.
Topics: Adult; Anticonvulsants; Epilepsy; Follow-Up Studies; Humans; Male; Oligospermia; Phenytoin; Sperm Count; Sperm Motility; Valproic Acid | 2005 |
Use of phenytoin and other anticonvulsant prophylaxis in patients with aneurysmal subarachnoid hemorrhage.
Topics: Cognition Disorders; Drug Interactions; Humans; Intracranial Aneurysm; Nimodipine; Phenytoin; Seizures; Subarachnoid Hemorrhage; Valproic Acid | 2005 |
[Anticonvulsive pharmacotherapy may aggravate epilepsy course].
Topics: Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Fructose; Humans; Magnetic Resonance Imaging; Phenobarbital; Phenytoin; Topiramate; Valproic Acid | 2005 |
2-phosphonomethyl-pentanedioic acid (glutamate carboxypeptidase II inhibitor) increases threshold for electroconvulsions and enhances the antiseizure action of valproate against maximal electroshock-induced seizures in mice.
Topics: Analysis of Variance; Animals; Anticonvulsants; Brain; Carbamazepine; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Glutamate Carboxypeptidase II; Male; Mice; Organophosphorus Compounds; Phenobarbital; Phenytoin; Psychomotor Performance; Seizures; Valproic Acid | 2006 |
Effects of common anti-epileptic drug monotherapy on serum levels of homocysteine, vitamin B12, folic acid and vitamin B6.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Phenytoin; Pyridoxal Phosphate; Reference Values; Valproic Acid; Vitamin B 12 | 2006 |
Fatal seizures due to potential herb-drug interactions with Ginkgo biloba.
Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Enzyme Induction; Fatal Outcome; Ginkgo biloba; Herb-Drug Interactions; Humans; Male; Middle Aged; Mixed Function Oxygenases; Phenytoin; Seizures; Valproic Acid | 2005 |
Transient occipitotemporal subcortical diffusion-weighted magnetic resonance imaging abnormalities associated with status epilepticus. Case report.
Topics: Adult; Carbamazepine; Diazepam; Diffusion Magnetic Resonance Imaging; Drug Administration Schedule; Electroencephalography; Humans; Injections, Intramuscular; Male; Occipital Lobe; Phenytoin; Severity of Illness Index; Status Epilepticus; Temporal Lobe; Time Factors; Valproic Acid | 2006 |
Total phenytoin concentrations do not accurately predict free phenytoin concentrations in critically ill children.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anticonvulsants; Blood Chemical Analysis; Cefazolin; Child; Child, Preschool; Critical Illness; Humans; Hypoalbuminemia; Infant; Infant, Newborn; Intensive Care Units, Pediatric; Phenytoin; Protein Binding; Retrospective Studies; Seizures; Sensitivity and Specificity; Valproic Acid | 2006 |
Acute and chronic effects of carbamazepine, phenytoin, valproate and vinpocetine on BAEP parameters and threshold in the guinea pig.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Auditory Pathways; Auditory Perception; Auditory Threshold; Brain Stem; Carbamazepine; Electrophysiology; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Male; Neural Conduction; Phenytoin; Reaction Time; Valproic Acid; Vinca Alkaloids | 2007 |
Anticonvulsant hypersensitivity syndrome: cross-reactivity with tricyclic antidepressant agents.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Benzodiazepines; Carbamazepine; Cross Reactions; Cyclohexanecarboxylic Acids; Doxepin; Drug Hypersensitivity; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Molecular Structure; Phenytoin; Skin Tests; Syndrome; Valproic Acid | 2006 |
Treatment of status epilepticus in adults: guidelines of the Italian League against Epilepsy.
Topics: Adult; Age Factors; Anesthesia, General; Anticonvulsants; Benzodiazepines; Humans; International Agencies; Italy; Lorazepam; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Propofol; Secondary Prevention; Status Epilepticus; Thiopental; Valproic Acid | 2006 |
Conventional anticonvulsant drugs in the guinea-pig kindling model of partial seizures: effects of repeated administration.
Topics: Action Potentials; Amygdala; Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Electric Stimulation; Epilepsies, Partial; Ethosuximide; Female; Guinea Pigs; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Predictive Value of Tests; Reproducibility of Results; Species Specificity; Treatment Outcome; Valproic Acid | 2007 |
Superior oblique myokymia: efficacy of medical treatment.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Diplopia; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Optical Illusions; Phenytoin; Propranolol; Retrospective Studies; Treatment Outcome; Trochlear Nerve Diseases; Valproic Acid | 2007 |
Population estimation of the effects of cytochrome P450 2C9 and 2C19 polymorphisms on phenobarbital clearance in Japanese.
Topics: Adult; Algorithms; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Asian People; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Monitoring; Epilepsy; Female; Gene Frequency; Genetics, Population; Heterozygote; Homozygote; Humans; Immunoassay; Isoxazoles; Japan; Male; Metabolic Clearance Rate; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Polymorphism, Genetic; Regression Analysis; Valproic Acid; Zonisamide | 2007 |
Sodium valproate vs phenytoin in status epilepticus: a pilot study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Female; Humans; India; Male; Middle Aged; Phenytoin; Pilot Projects; Status Epilepticus; Treatment Outcome; Valproic Acid | 2007 |
Clinical utility of a continuous intravenous infusion of valproic acid in pediatric patients.
Topics: Administration, Oral; Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Drug Utilization Review; Female; Fructose; Hallucinations; Humans; Hyperammonemia; Infusions, Intravenous; Male; Medical Records; Metabolic Clearance Rate; Migraine Disorders; Phenobarbital; Phenytoin; Retrospective Studies; Seizures; Topiramate; Treatment Outcome; Valproic Acid | 2007 |
Antiepileptic drugs prevent changes induced by pilocarpine model of epilepsy in brain ecto-nucleotidases.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Anticonvulsants; Brain; Carbamazepine; Cerebral Cortex; Epilepsy; Hippocampus; Male; Muscarinic Agonists; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Synaptosomes; Valproic Acid | 2007 |
An ImmunoChip prototype for simultaneous detection of antiepileptic drugs using an enhanced one-step homogeneous immunoassay.
Topics: Anticonvulsants; Carbamazepine; Humans; Immunoassay; Phenytoin; Reagent Kits, Diagnostic; Sensitivity and Specificity; Valproic Acid | 2007 |
Chronically administered fluoxetine enhances the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Interactions; Drug Synergism; Electroshock; Fluoxetine; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Selective Serotonin Reuptake Inhibitors; Valproic Acid | 2007 |
Interactions between two enantiomers of losigamone and conventional antiepileptic drugs in the mouse maximal electroshock model--an isobolographic analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Interactions; Electroshock; Furans; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Stereoisomerism; Valproic Acid | 2007 |
Guidelines for the management of severe traumatic brain injury. XIII. Antiseizure prophylaxis.
Topics: Anticonvulsants; Brain Injuries; Humans; Phenytoin; Seizures; Time Factors; Valproic Acid | 2007 |
[[Severe phenytoin intoxication in patients with hypoalbuminaemia].
Topics: Anticonvulsants; Drug Interactions; Humans; Phenytoin; Valproic Acid | 2007 |
Phenytoin but not valproate directly affected in vitro trophoblast differentiation.
Topics: Anticonvulsants; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Phenytoin; Pregnancy; Pregnancy Complications; Trophoblasts; Valproic Acid | 2008 |
Isobolographic analysis of interactions between remacemide and conventional antiepileptic drugs in the mouse model of maximal electroshock.
Topics: Acetamides; Algorithms; Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Interactions; Electroshock; Epilepsy; Epilepsy, Tonic-Clonic; Male; Memory; Mice; Motor Skills; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2007 |
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Drug Monitoring; Ethosuximide; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature; Triazines; Valproic Acid; Zonisamide | 2007 |
Levetiracetam, phenytoin, and valproate act differently on rat bone mass, structure, and metabolism.
Topics: Animals; Anticonvulsants; Biomarkers; Biomechanical Phenomena; Bone and Bones; Bone Density; Compressive Strength; Dose-Response Relationship, Drug; Female; Femur Neck; Levetiracetam; Models, Animal; Osteogenesis; Phenytoin; Piracetam; Rats; Rats, Wistar; Valproic Acid | 2007 |
Cholecalciferol enhances the anticonvulsant effect of conventional antiepileptic drugs in the mouse model of maximal electroshock.
Topics: Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Cholecalciferol; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Injections, Intraperitoneal; Male; Mental Recall; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Vitamins | 2007 |
Acute and chronic treatment with mianserin differentially affects the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model.
Topics: Analysis of Variance; Animals; Anticonvulsants; Antidepressive Agents, Second-Generation; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Electroshock; Fluorescent Antibody Technique; Male; Memory; Mianserin; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2007 |
Non-convulsive status epilepticus secondary to valproic acid-induced hyperammonemic encephalopathy.
Topics: Adult; Ammonia; Anticonvulsants; Brain; Electroencephalography; Hepatic Encephalopathy; Humans; Hyperammonemia; Liver; Male; Midazolam; Phenytoin; Status Epilepticus; Valproic Acid | 2007 |
Searching for a needle in a haystack: use of ICD-9-CM codes in drug-induced liver injury.
Topics: Adolescent; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Infant; International Classification of Diseases; Isoniazid; Liver Diseases; Male; Medical Records Systems, Computerized; Michigan; Middle Aged; Phenytoin; Population Surveillance; Sensitivity and Specificity; United States; Valproic Acid | 2007 |
Screening for the effects of antiepileptic drugs on short term plasticity using a time efficient bioassay.
Topics: Animals; Anticonvulsants; Biological Assay; Carbamazepine; Electrophysiology; Equipment Design; Hippocampus; Male; Models, Statistical; Neuronal Plasticity; Phenytoin; Poisson Distribution; Rats; Time Factors; Valproic Acid | 2007 |
The effect of anticonvulsant drugs on the fibrinolytic activity of tissue plasminogen activator.
Topics: Adult; Anticonvulsants; Blood Coagulation; Drug Interactions; Erythropoietin; Female; Fibrinolytic Agents; Humans; In Vitro Techniques; Levetiracetam; Male; Phenobarbital; Phenytoin; Piracetam; Recombinant Proteins; Tissue Plasminogen Activator; Valproic Acid | 2008 |
Increased P-glycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbamazepine; Cells, Cultured; Cerebral Arteries; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelial Cells; Immunosuppressive Agents; Indicators and Reagents; Microcirculation; Phenobarbital; Phenytoin; Rats; Rhodamine 123; Sodium Channel Blockers; Time; Up-Regulation; Valproic Acid; Verapamil | 2008 |
The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models.
Topics: Administration, Oral; Animals; Anticonvulsants; Disease Models, Animal; Injections, Intraperitoneal; Mice; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Seizures; Severity of Illness Index; Triazoles; Valproic Acid | 2008 |
Contraindications to phenytoin in emergency department patients with seizures.
Topics: Anticonvulsants; Contraindications; Emergency Service, Hospital; Epilepsy; Female; Humans; Levetiracetam; Male; Middle Aged; Phenytoin; Piracetam; Pregnancy; Retrospective Studies; Valproic Acid | 2009 |
Simultaneous toxicities in a child on multiple anticonvulsants.
Topics: Anticonvulsants; Bone Marrow; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Child, Preschool; Drug Synergism; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Liver; Liver Diseases; Lorazepam; Parainfluenza Virus 3, Human; Paramyxoviridae Infections; Phenytoin; Status Epilepticus; Triazines; Valproic Acid | 2008 |
Postictal transient hyperammonemia.
Topics: Adult; Anticonvulsants; Epilepsy, Tonic-Clonic; Humans; Hyperammonemia; Liver Function Tests; Male; Middle Aged; Phenytoin; Tomography, X-Ray Computed; Valproic Acid | 2008 |
Bone health in young women with epilepsy after one year of antiepileptic drug monotherapy.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Biomarkers; Bone Density; Bone Diseases, Metabolic; Bone Remodeling; Calcium, Dietary; Carbamazepine; Collagen Type I; Epilepsy; Female; Femur; Humans; Lamotrigine; Life Style; Lumbar Vertebrae; Minerals; Parathyroid Hormone; Peptides; Phenytoin; Surveys and Questionnaires; Triazines; Valproic Acid; Vitamin D | 2008 |
Re: New lessons: classic treatments in convulsive status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Diazepam; Humans; Lorazepam; Phenytoin; Status Epilepticus; Valproic Acid | 2008 |
A confusing case of confusion. Acute porphyrias.
Topics: Acidosis, Lactic; Acute Disease; Anticonvulsants; Brain; Confusion; Diagnosis, Differential; Diet, Reducing; Drug Combinations; Electroencephalography; Epilepsy, Tonic-Clonic; Estrogens, Conjugated (USP); Fatal Outcome; Female; Headache; Hormone Replacement Therapy; Humans; Magnetic Resonance Imaging; Medroxyprogesterone Acetate; Middle Aged; Phenobarbital; Phenytoin; Porphyrias; Spinal Puncture; Tomography, X-Ray Computed; Valproic Acid; Vomiting; Weight Loss | 2008 |
Treatment emergent mania responding to valproate in a Chinese female adolescent population with eating disorders: a case series.
Topics: Adolescent; Anorexia Nervosa; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Bulimia Nervosa; Feeding and Eating Disorders; Female; Humans; Isoxazoles; Male; Phenytoin; Risk Factors; Sex Characteristics; Singapore; Valproic Acid; Young Adult; Zonisamide | 2008 |
Status epilepticus in central nervous system infections: an experience from a developing country.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Central Nervous System Infections; Developing Countries; Diazepam; Drug Resistance; Electroencephalography; Female; Hospitals, Teaching; Humans; India; Lorazepam; Magnetic Resonance Imaging; Male; Midazolam; Middle Aged; Phenytoin; Prospective Studies; Status Epilepticus; Valproic Acid | 2008 |
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cysteine; Dipeptides; Drug Evaluation; Epilepsy; Female; Folic Acid; Humans; Hyperhomocysteinemia; Liver; Male; Methionine; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Riboflavin; Valproic Acid; Vitamin B Deficiency | 2008 |
Enhanced clearance of highly protein-bound drugs by albumin-supplemented dialysate during modeled continuous hemodialysis.
Topics: Albumins; Animals; Carbamazepine; Cattle; Drug-Related Side Effects and Adverse Reactions; Hemodialysis Solutions; Humans; In Vitro Techniques; Models, Biological; Phenytoin; Poisoning; Protein Binding; Renal Dialysis; Valproic Acid | 2009 |
[Posterior reversible leukoencephalopathy in a patient with postpartum eclampsia].
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Brain; Brain Edema; Cesarean Section; Diazepam; Drug Therapy, Combination; Eclampsia; Female; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Midazolam; Phenytoin; Posterior Leukoencephalopathy Syndrome; Postoperative Complications; Pregnancy; Puerperal Disorders; Seizures; Valproic Acid | 2008 |
Effect of phenytoin and valproic acid therapy on serum lipid levels and liver function tests.
Topics: Anticonvulsants; Case-Control Studies; Child; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Epilepsy; Female; Humans; Liver Function Tests; Male; Phenytoin; Triglycerides; Valproic Acid | 2008 |
Patterns of antiepileptic drug overdose differ between men and women: admissions to the Edinburgh Poisons Unit, 2000-2007.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Overdose; Female; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Psychotic Disorders; Retrospective Studies; Sex Distribution; Suicide, Attempted; Triazines; Valproic Acid; Young Adult | 2009 |
[Case of juvenile myoclonic epilepsy misdiagnosed as simple partial seizure for more than 60 years].
Topics: Aged; Cerebellar Ataxia; Diagnostic Errors; Electroencephalography; Electromyography; Epilepsies, Partial; Female; Humans; Magnetic Resonance Imaging; Myoclonic Epilepsy, Juvenile; Phenytoin; Treatment Outcome; Valproic Acid | 2009 |
Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child, Preschool; Cognition; Developmental Disabilities; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Intelligence; Intelligence Tests; Lamotrigine; Neuropsychological Tests; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prospective Studies; Regression Analysis; Triazines; Valproic Acid | 2009 |
N-(anilinomethyl)-p-isopropoxyphenylsuccinimide potentiates the anticonvulsant action of phenobarbital and valproate in the mouse maximal electroshock-induced seizure model.
Topics: Aniline Compounds; Animals; Anticonvulsants; Brain; Carbamazepine; Dose-Response Relationship, Drug; Drug Synergism; Male; Memory; Mice; Models, Animal; Motor Activity; Muscle Strength; Phenobarbital; Phenytoin; Seizures; Succinimides; Valproic Acid | 2009 |
Effect of pharmacist participation in the health care team on therapeutic drug monitoring utilization for antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Drug Monitoring; Epilepsy; Female; Humans; Male; Middle Aged; Patient Care Team; Pharmacists; Phenytoin; Valproic Acid | 2009 |
Valproic acid: long-term effects on children exposed in utero.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Contraindications; Dose-Response Relationship, Drug; Epilepsy; Female; Fructose; Humans; Intelligence; Lamotrigine; Language Development Disorders; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Psychomotor Disorders; Topiramate; Triazines; Valproic Acid | 2009 |
Adverse effects of carbamazepine, phenytoin, valproate and lamotrigine monotherapy in epileptic adult Chinese patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; China; Drug Eruptions; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Patient Acceptance of Health Care; Phenytoin; Survival Analysis; Treatment Failure; Triazines; Valproic Acid; Young Adult | 2010 |
Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients.
Topics: Adolescent; Adult; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbamazepine; Epilepsy; Female; Genotype; Humans; Male; Pharmacogenetics; Phenobarbital; Phenytoin; Valproic Acid; Young Adult | 2010 |
Synthesis and anticonvulsant activity of 4-oxo and 4-thioxo-8-bromobenzopyran derivatives.
Topics: Animals; Anticonvulsants; Benzopyrans; Electroshock; Indicators and Reagents; Lethal Dose 50; Male; Mice; Nervous System Diseases; Pentylenetetrazole; Phenytoin; Seizures; Stereoisomerism; Structure-Activity Relationship; Valproic Acid | 2010 |
Effect of antiepileptic drugs and reactive oxygen species on folate receptor 1 (FOLR1)-dependent 5-methyltetrahydrofolate transport.
Topics: Anticonvulsants; Carbamazepine; Folate Receptor 1; Humans; Phenytoin; Reactive Oxygen Species; RNA, Small Interfering; Tetrahydrofolates; Valproic Acid | 2010 |
Presence of epileptiform discharges on initial EEGs are associated with failure of retention on first antiepileptic drug in newly diagnosed cryptogenic partial epilepsy: a 2-year observational study.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Carbamazepine; Electroencephalography; Epilepsy, Complex Partial; Female; Fructose; Humans; Kaplan-Meier Estimate; Lamotrigine; Male; Middle Aged; Phenytoin; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2010 |
Effects of three N-(carboxyanilinomethyl) derivatives of p-isopropoxyphenylsuccinimide on the anticonvulsant action of carbamazepine, phenobarbital, phenytoin and valproate in the mouse maximal electroshock-induced seizure model.
Topics: Aniline Compounds; Animals; Anticonvulsants; Behavior, Animal; Brain; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Male; Memory; Mice; Motor Activity; Muscle Strength; Muscle, Skeletal; Phenobarbital; Phenytoin; Seizures; Succinimides; Valproic Acid | 2010 |
The role of intravenous valproate in convulsive status epilepticus in the future.
Topics: Anticonvulsants; Humans; Injections, Intravenous; Liver; Pancreatitis; Phenytoin; Practice Guidelines as Topic; Status Epilepticus; Valproic Acid | 2010 |
Age and comedications influence levetiracetam pharmacokinetics in children.
Topics: Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Metabolic Clearance Rate; Oxcarbazepine; Phenytoin; Piracetam; Retrospective Studies; Triazines; Valproic Acid | 2010 |
Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Child; China; Clonazepam; Cyclohexanecarboxylic Acids; Exanthema; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Medicine, Chinese Traditional; Middle Aged; Phenobarbital; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Triazines; Valproic Acid; Young Adult | 2010 |
Status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Child; Clinical Protocols; Fructose; GABA Modulators; Humans; Ketamine; Levetiracetam; Midazolam; Pentobarbital; Phenobarbital; Phenytoin; Piracetam; Propofol; Status Epilepticus; Thiopental; Topiramate; Valproic Acid | 2011 |
Synthetic cannabinoid WIN 55,212-2 mesylate enhances the protective action of four classical antiepileptic drugs against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzoxazines; Cannabinoid Receptor Agonists; Carbamazepine; Drug Synergism; Electroshock; Male; Memory, Long-Term; Mice; Morpholines; Muscle Strength; Naphthalenes; Phenobarbital; Phenytoin; Psychomotor Performance; Seizures; Valproic Acid | 2011 |
Retrograde ejaculation and abnormal hormonal profile in a subject under treatment with valproate and phenytoin.
Topics: Anticonvulsants; Ejaculation; Hormones; Humans; Male; Middle Aged; Phenytoin; Sexual Dysfunction, Physiological; Valproic Acid | 2010 |
Subacute encephalopathy and seizures in alcoholics (SESA) presenting with non-convulsive status epilepticus.
Topics: Acetamides; Alcohol Withdrawal Seizures; Alcoholism; Anticonvulsants; Brain Diseases; Confusion; Diffusion Magnetic Resonance Imaging; Electroencephalography; Female; Humans; Lacosamide; Lorazepam; Middle Aged; Neurologic Examination; Paresis; Patient Compliance; Phenytoin; Seizures; Status Epilepticus; Tomography, X-Ray Computed; Valproic Acid | 2011 |
Second-line status epilepticus treatment: comparison of phenytoin, valproate, and levetiracetam.
Topics: Aged; Analysis of Variance; Anticonvulsants; Chi-Square Distribution; Female; Humans; Levetiracetam; Logistic Models; Male; Middle Aged; Multivariate Analysis; Phenytoin; Piracetam; Retrospective Studies; Status Epilepticus; Treatment Failure; Valproic Acid | 2011 |
Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes.
Topics: Adolescent; Adult; Aged; Amines; Animals; Anticonvulsants; Calcium; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Neocortex; Nipecotic Acids; Oximes; Phenytoin; Piracetam; Potassium; Pregabalin; Rats; Rats, Wistar; Synaptosomes; Tetanus Toxin; Tetrodotoxin; Triazines; Valproic Acid; Veratridine; Young Adult | 2011 |
Thyroid status in a large cohort of patients with mental retardation: the TOP-R (Thyroid Origin of Psychomotor Retardation) study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Cohort Studies; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Hypothyroidism; Intellectual Disability; Lamotrigine; Linear Models; Male; Middle Aged; Netherlands; Phenobarbital; Phenytoin; Prevalence; Thyroid Gland; Thyrotropin; Thyroxine; Triazines; Triiodothyronine; Valproic Acid | 2011 |
Pharmacokinetic and pharmacodynamic interactions of valproate, phenytoin, phenobarbitone and carbamazepine with curcumin in experimental models of epilepsy in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Curcumin; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Epilepsy; Male; Maze Learning; Phenobarbital; Phenytoin; Random Allocation; Rats; Rats, Wistar; Valproic Acid | 2011 |
Clinical and pharmacy utilization outcomes with brand to generic antiepileptic switches in patients with epilepsy.
Topics: Anticonvulsants; Drug Substitution; Drugs, Generic; Emergency Service, Hospital; Epilepsy; Female; Hospitalization; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Proportional Hazards Models; Regression Analysis; Retrospective Studies; Treatment Outcome; Triazines; Valproic Acid | 2011 |
[Epilepsy in elderly].
Topics: Aged; Aged, 80 and over; Aging; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Female; Fructose; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Topiramate; Triazines; Valproic Acid | 2011 |
Gingival enlargement.
Topics: Adult; Anticonvulsants; Collagen; Dental Scaling; Female; Gingival Overgrowth; Gingivectomy; Guided Tissue Regeneration, Periodontal; Humans; Phenytoin; Root Planing; Subgingival Curettage; Surgical Flaps; Valproic Acid | 2011 |
The interactions of atorvastatin and fluvastatin with carbamazepine, phenytoin and valproate in the mouse maximal electroshock seizure model.
Topics: Animals; Anticonvulsants; Atorvastatin; Brain; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Indoles; Male; Memory; Mice; Motor Activity; Phenytoin; Pyrroles; Seizures; Valproic Acid | 2012 |
Effects of long-term antiepileptic drug monotherapy on vascular risk factors and atherosclerosis.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Atherosclerosis; Blood Glucose; Carbamazepine; Carotid Artery, Common; Cross-Sectional Studies; Epilepsy; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Phenytoin; Risk Factors; Time Factors; Uric Acid; Valproic Acid; Young Adult | 2012 |
Use of single- and multi-drug regimens in the management of classic (idiopathic) trigeminal neuralgia: an 11-year experience at a single Sri Lankan institution.
Topics: Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Pain Measurement; Phenytoin; Retrospective Studies; Sri Lanka; Treatment Outcome; Trigeminal Neuralgia; Valproic Acid | 2012 |
Thyroid hormones may contribute to vascular risk factors and atherosclerosis.
Topics: Anticonvulsants; Atherosclerosis; Carbamazepine; Carotid Artery, Common; Epilepsy; Female; Humans; Male; Phenytoin; Valproic Acid | 2012 |
Variability of carbamazepine and valproate concentrations in elderly nursing home residents.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Data Interpretation, Statistical; Databases, Factual; Female; Humans; Male; Nursing Homes; Patients; Phenytoin; Seizures; Valproic Acid | 2012 |
Characterization of glucose homeostasis and lipid profile in adult, seizure-free, epileptic patients in Asian population.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Asian People; Blood Glucose; Cholesterol, LDL; Cross-Sectional Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Glucose Tolerance Test; Humans; Insulin Resistance; Lipid Metabolism; Male; Middle Aged; Phenytoin; Thailand; Triglycerides; Valproic Acid | 2012 |
Seizure management at Auckland City Hospital Emergency Department between July and December 2009: time for a change?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Disease Management; Emergency Medical Services; Emergency Service, Hospital; Epilepsy; Female; Hospitals, Urban; Humans; Male; Middle Aged; New Zealand; Patient Care Team; Phenytoin; Retrospective Studies; Seasons; Seizures; Status Epilepticus; Tertiary Care Centers; Valproic Acid; Young Adult | 2012 |
The effect of combination therapy on the plasma concentrations of traditional antiepileptics: a retrospective study.
Topics: Adolescent; Adult; Age Factors; Aged; Analysis of Variance; Anticonvulsants; Carbamazepine; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Retrospective Studies; Risk Assessment; Risk Factors; Sex Factors; Valproic Acid; Young Adult | 2012 |
Phenytoin-induced acute orofacial dyskinesia.
Topics: Aged, 80 and over; Anticonvulsants; Epilepsy, Tonic-Clonic; Hematoma, Subdural; Humans; Male; Movement Disorders; Phenytoin; Postoperative Complications; Tomography, X-Ray Computed; Valproic Acid | 2013 |
Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report.
Topics: Anticonvulsants; Denture, Complete; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Gingiva; Gingival Hyperplasia; Gingival Overgrowth; Gingivectomy; Humans; Jaw, Edentulous, Partially; Middle Aged; Phenobarbital; Phenytoin; Tooth Extraction; Tooth Mobility; Valproic Acid | 2012 |
Asymmetric dimethylarginine may contribute to vascular risk factors in patients receiving antiepileptic drug treatment.
Topics: Anticonvulsants; Atherosclerosis; Carbamazepine; Carotid Artery, Common; Epilepsy; Female; Humans; Male; Phenytoin; Valproic Acid | 2012 |
Comparative stroke risk of antiepileptic drugs in patients with epilepsy.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Propensity Score; Proportional Hazards Models; Retrospective Studies; Risk Factors; Stroke; Valproic Acid; Young Adult | 2013 |
Treatment of status epilepticus: an international survey of experts.
Topics: Administration, Intravenous; Adult; Anticonvulsants; Child; Consensus; Expert Testimony; Humans; Hypnotics and Sedatives; Levetiracetam; Lorazepam; Midazolam; Pentobarbital; Phenytoin; Piracetam; Propofol; Societies, Medical; Status Epilepticus; Surveys and Questionnaires; Valproic Acid | 2013 |
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)?
Topics: Anticonvulsants; Carbamazepine; Drug Discovery; Epilepsy; Ethosuximide; History, 20th Century; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Structure-Activity Relationship; Succinimides; Valproic Acid | 2012 |
Antiepileptic drugs prevent changes in adenosine deamination during acute seizure episodes in adult zebrafish.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Male; Pentylenetetrazole; Phenytoin; Seizures; Valproic Acid; Zebrafish | 2013 |
Risk factors for hyperammonemia in pediatric patients with epilepsy.
Topics: Acetazolamide; Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy; Female; Fructose; Humans; Hyperammonemia; Infant; Isoxazoles; Male; Phenobarbital; Phenytoin; Retrospective Studies; Risk Factors; Sex Factors; Topiramate; Valproic Acid; Zonisamide | 2013 |
Drug rash with eosinophilia and systemic symptoms syndrome associated with use of phenytoin, divalproex sodium, and phenobarbital.
Topics: Adult; Drug Eruptions; Drug Substitution; Eosinophilia; Female; Humans; Phenobarbital; Phenytoin; Valproic Acid | 2013 |
The quantitative effect of serum albumin, serum urea, and valproic acid on unbound phenytoin concentrations in children.
Topics: Adolescent; Anticonvulsants; Bilirubin; Carbamazepine; Child; Child, Preschool; Databases, Factual; Female; Humans; Infant; Infant, Newborn; Male; Netherlands; Nonlinear Dynamics; Phenytoin; Protein Binding; Retrospective Studies; Serum Albumin; Urea; Valproic Acid | 2014 |
Evaluating appropriateness of digoxin, carbamazepine, valproic acid, and phenytoin usage by therapeutic drug monitoring.
Topics: Animals; Carbamazepine; Digoxin; Humans; Monitoring, Physiologic; Phenytoin; Valproic Acid | 2013 |
Levetiracetam add-on therapy in Japanese patients with refractory partial epilepsy.
Topics: Adult; Anticonvulsants; Benzodiazepines; Clobazam; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Complex Partial; Female; Fructose; Humans; Japan; Lamotrigine; Levetiracetam; Male; Middle Aged; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2013 |
Anti-epileptic drugs inhibit viability of synoviocytes in vitro.
Topics: Animals; Anticonvulsants; Arthritis, Rheumatoid; Carbamazepine; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Histone Deacetylase Inhibitors; Humans; Phenobarbital; Phenytoin; Rabbits; Synovial Membrane; Valproic Acid | 2013 |
A case of selective immunoglobulin A deficiency with anti-neutrophil cytoplasmic antibody-associated glomerulonephritis.
Topics: Antibodies, Antineutrophil Cytoplasmic; Antibodies, Antinuclear; Anticonvulsants; Epilepsy; Female; Glomerulonephritis; Humans; IgA Deficiency; Middle Aged; Phenytoin; Valproic Acid | 2014 |
Effect of CYP3A5 genotypes on the pharmacokinetics of carbamazepine when used as monotherapy or co-administered with phenytoin, phenobarbital or valproic acid in Thai patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Asian People; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Female; Genotype; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid; Young Adult | 2013 |
Antiepileptic drug utilization in Bangladesh: experience from Dhaka Medical College Hospital.
Topics: Adolescent; Adult; Anticonvulsants; Bangladesh; Carbamazepine; Child; Drug Combinations; Epilepsies, Partial; Epilepsy, Generalized; Female; Follow-Up Studies; Fructose; Hospitals, Teaching; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prohibitins; Retrospective Studies; Seizures; Topiramate; Treatment Outcome; Valproic Acid | 2013 |
Glia and epilepsy: experimental investigation of antiepileptic drugs in an astroglia/microglia co-culture model of inflammation.
Topics: Amines; Animals; Anticonvulsants; Astrocytes; Blotting, Western; Carbamazepine; Cells, Cultured; Coculture Techniques; Connexin 43; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Gap Junctions; Inflammation; Microglia; Neuroglia; Phenytoin; Rats; Rats, Wistar; Transforming Growth Factor beta1; Valproic Acid | 2014 |
Drug interaction between phenytoin and valproic acid in a child with refractory epilepsy: a case report.
Topics: Anticonvulsants; Child; Drug Interactions; Epilepsy; Female; Humans; Phenytoin; Valproic Acid | 2014 |
Lacosamide serum concentrations in adult patients with epilepsy: the influence of gender, age, dose, and concomitant antiepileptic drugs.
Topics: Acetamides; Adult; Aged; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Female; Humans; Lacosamide; Male; Middle Aged; Phenytoin; Retrospective Studies; Seizures; Valproic Acid | 2014 |
[Case of non-convulsive status epilepticus after influenza virus B infection].
Topics: Adult; Anticonvulsants; Electroencephalography; Female; Humans; Influenza B virus; Influenza, Human; Methylprednisolone; Phenytoin; Prednisolone; Pulse Therapy, Drug; Status Epilepticus; Treatment Outcome; Valproic Acid; Young Adult | 2014 |
[Effect of capecitabine therapy on the blood levels of antiepileptic drugs - report of two cases].
Topics: Anticonvulsants; Antimetabolites, Antineoplastic; Brain Neoplasms; Breast Neoplasms; Capecitabine; Deoxycytidine; Drug Interactions; Female; Fluorouracil; Humans; Middle Aged; Phenytoin; Seizures; Valproic Acid | 2014 |
Phenytoin and sodium valproate but not levetiracetam induce bone alterations in female mice.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Anticonvulsants; Biomarkers; Bone Density; Calcium; Female; Hydroxyproline; Isoenzymes; Levetiracetam; Lumbar Vertebrae; Mice; Phenytoin; Piracetam; Tartrate-Resistant Acid Phosphatase; Valproic Acid | 2014 |
Raloxifene preserves phenytoin and sodium valproate induced bone loss by modulating serum estradiol and TGF-β3 content in bone of female mice.
Topics: Animals; Anticonvulsants; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Diseases; Estradiol; Female; Mice; Phenytoin; Raloxifene Hydrochloride; Seizures; Selective Estrogen Receptor Modulators; Transforming Growth Factor beta3; Valproic Acid | 2014 |
4217C>A polymorphism in carbamoyl-phosphate synthase 1 gene may not associate with hyperammonemia development during valproic acid-based therapy.
Topics: Alleles; Amino-Acid N-Acetyltransferase; Ammonia; Anticonvulsants; Asian People; Biomarkers, Pharmacological; Carbamoyl-Phosphate Synthase (Ammonia); Child; Epilepsy; Female; Genetic Predisposition to Disease; Humans; Hyperammonemia; Japan; Male; Phenytoin; Polymorphism, Single Nucleotide; Risk Factors; Valproic Acid | 2014 |
Reboxetine and its influence on the action of classical antiepileptic drugs in the mouse maximal electroshock model.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Epilepsy; Male; Memory, Long-Term; Mice; Morpholines; Motor Activity; Phenobarbital; Phenytoin; Reboxetine; Valproic Acid | 2014 |
Interaction of famotidine, an H2 histamine receptor antagonist, with conventional antiepileptic drugs in mice.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Drug Interactions; Electroshock; Famotidine; Histamine H2 Antagonists; Male; Memory, Long-Term; Mice; Phenobarbital; Phenytoin; Psychomotor Performance; Valproic Acid | 2014 |
Interaction of injectable neurotropic drugs with the red cell membrane.
Topics: Central Nervous System Agents; Chlorpromazine; Citalopram; Clomipramine; Clonazepam; Diazepam; Erythrocytes; Humans; Injections; Levetiracetam; Microscopy, Electron, Scanning; Neurotransmitter Agents; Phenobarbital; Phenytoin; Piracetam; Valproic Acid | 2014 |
Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma.
Topics: Animals; Atropine; Captopril; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Flutamide; Lamivudine; Liver; Male; Mannitol; Metabolomics; Methotrexate; Neomycin; Oxidative Stress; Phenytoin; Piperazines; Propylthiouracil; Rats; Rats, Wistar; Streptomycin; Triazoles; Valproic Acid; Vancomycin; Zidovudine | 2014 |
Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases.
Topics: Amines; Anticonvulsants; Carbamazepine; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Limit of Detection; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tiagabine; Topiramate; Triazines; Valproic Acid | 2014 |
Effect of comedication on lamotrigine clearance in Korean epilepsy patients.
Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Half-Life; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Triazines; Valproic Acid | 2015 |
Clinical validation and implications of dried blood spot sampling of carbamazepine, valproic acid and phenytoin in patients with epilepsy.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Dried Blood Spot Testing; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Treatment Outcome; Valproic Acid; Young Adult | 2014 |
Low dose zinc supplementation beneficially affects seizure development in experimental seizure models in rats.
Topics: Animals; Anticonvulsants; Dietary Supplements; Disease Models, Animal; Male; Phenytoin; Rats; Rats, Wistar; Seizures; Valproic Acid; Zinc | 2015 |
Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Resistance; Electrodes, Implanted; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hippocampus; Kainic Acid; Levetiracetam; Mice; Phenobarbital; Phenytoin; Piracetam; Seizures; Valproic Acid | 2015 |
Cosmetic side effects of antiepileptic drugs in adults with epilepsy.
Topics: Acne Vulgaris; Adult; Alopecia; Anticonvulsants; Epilepsy; Female; gamma-Aminobutyric Acid; Gingival Diseases; Hirsutism; Humans; Levetiracetam; Male; Middle Aged; Phenytoin; Piracetam; Pregabalin; Risk Factors; Sex Factors; Valproic Acid; Weight Gain | 2015 |
Effects of phenytoin and valproic acid on cognitive functions of Thai epileptic patients: a pilot study.
Topics: Adolescent; Adult; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Cognition; Epilepsy; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Phenytoin; Pilot Projects; Thailand; Treatment Outcome; Valproic Acid | 2014 |
Comparative behavioral and neurochemical analysis of phenytoin and valproate treatment on epilepsy induced learning and memory deficit: Search for add on therapy.
Topics: Acetylcholinesterase; Animals; Anticonvulsants; Cerebral Cortex; Drug Therapy, Combination; Epilepsy; Learning; Male; Memory Disorders; Mice; Phenytoin; Treatment Outcome; Valproic Acid | 2015 |
Modafinil and its metabolites enhance the anticonvulsant action of classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzhydryl Compounds; Brain; Carbamazepine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Electroshock; Hand Strength; Male; Mice; Modafinil; Phenobarbital; Phenytoin; Psychomotor Performance; Seizures; Sulfones; Valproic Acid | 2015 |
Antiepileptic prophylaxis following severe traumatic brain injury within a military cohort.
Topics: Adult; Anticonvulsants; Brain Injuries; Carbamazepine; Case-Control Studies; Chemoprevention; Cohort Studies; Humans; Levetiracetam; Military Personnel; Phenytoin; Piracetam; Retrospective Studies; Seizures; Trauma Severity Indices; Valproic Acid | 2016 |
Cross-species pharmacological characterization of the allylglycine seizure model in mice and larval zebrafish.
Topics: Allylglycine; Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Fructose; Levetiracetam; Male; Mice; Phenytoin; Piracetam; Seizures; Topiramate; Treatment Outcome; Valproic Acid; Zebrafish | 2015 |
Independent predictors of delay in emergence from general anesthesia.
Topics: Adult; Ambulatory Care; Anesthesia, Dental; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Anticonvulsants; Benzodiazepines; Clobazam; Clonazepam; Cohort Studies; Delayed Emergence from Anesthesia; Dental Care for Disabled; Female; Follow-Up Studies; Humans; Intellectual Disability; Male; Methyl Ethers; Phenobarbital; Phenytoin; Piperidines; Propofol; Remifentanil; Retrospective Studies; Risk Factors; Sevoflurane; Valproic Acid | 2015 |
Synergistic effect of docosahexaenoic acid on anticonvulsant activity of valproic acid and lamotrigine in animal seizure models.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Electroshock; Epilepsy; Kindling, Neurologic; Lamotrigine; Male; Mice; Pentylenetetrazole; Phenytoin; Rats; Rats, Wistar; Seizures; Triazines; Valproic Acid | 2015 |
Effect of xanthotoxin (8-methoxypsoralen) on the anticonvulsant activity of classical antiepileptic drugs against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Male; Methoxsalen; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2015 |
Efficacy of phenytoin, valproic acid, carbamazepine and new antiepileptic drugs on control of late-onset post-stroke epilepsy in Taiwan.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Cohort Studies; Female; Humans; Male; Middle Aged; National Health Programs; Outcome Assessment, Health Care; Phenytoin; Seizures; Stroke; Taiwan; Valproic Acid | 2015 |
Pediatric Herpes Simplex Virus Encephalitis Complicated by N-Methyl-D-aspartate Receptor Antibody Encephalitis.
Topics: Acyclovir; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Antiviral Agents; Autoantibodies; Clonidine; Diazepam; Encephalitis, Herpes Simplex; Encephalomalacia; Female; Fever; Humans; Immunocompromised Host; Immunosuppression Therapy; Infant; Leukoencephalopathies; Movement Disorders; Neurological Rehabilitation; Pakistan; Paresis; Phenobarbital; Phenytoin; Plasmapheresis; Receptors, N-Methyl-D-Aspartate; Seizures; Trihexyphenidyl; United Kingdom; Valproic Acid | 2015 |
Effects of CYP3A4/5 and ABCB1 genetic polymorphisms on carbamazepine metabolism and transport in Chinese patients with epilepsy treated with carbamazepine in monotherapy and bitherapy.
Topics: Adolescent; Adult; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; Carbamazepine; Child; China; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Epilepsy; Female; Genotype; Humans; Male; Middle Aged; Pharmacogenetics; Phenobarbital; Phenytoin; Polymorphism, Single Nucleotide; Valproic Acid; Young Adult | 2015 |
Influence of glutamine synthetase gene polymorphisms on the development of hyperammonemia during valproic acid-based therapy.
Topics: Adolescent; Ammonia; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Genotype; Glutamate-Ammonia Ligase; Humans; Hyperammonemia; Infant; Infant, Newborn; Logistic Models; Male; Phenytoin; Polymorphism, Genetic; Sex Factors; Valproic Acid | 2015 |
Dexamethasone alone and in combination with desipramine, phenytoin, valproic acid or levetiracetam interferes with 5-ALA-mediated PpIX production and cellular retention in glioblastoma cells.
Topics: Aminolevulinic Acid; Anti-Inflammatory Agents; Anticonvulsants; Desipramine; Dexamethasone; Drug Therapy, Combination; Enzyme Inhibitors; Fluorescence; Glioblastoma; Humans; Levetiracetam; Phenytoin; Photosensitizing Agents; Piracetam; Protoporphyrins; Valproic Acid | 2016 |
Modulation of brain glutamate dehydrogenase as a tool for controlling seizures.
Topics: Animals; Anticonvulsants; Brain; Deamination; Diazepam; Disease Models, Animal; Enzyme Inhibitors; Glutamate Dehydrogenase; Glutamic Acid; Ketoglutaric Acids; Male; Mice; Oxidation-Reduction; Oxygen Consumption; Pentylenetetrazole; Phenytoin; Seizures; Time Factors; Valproic Acid | 2015 |
Mexiletine and its Interactions with Classical Antiepileptic Drugs: An Isobolographic Analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Interactions; Electroshock; Male; Memory, Long-Term; Mexiletine; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Tissue Distribution; Valproic Acid | 2016 |
Propafenone enhances the anticonvulsant action of classical antiepileptic drugs in the mouse maximal electroshock model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Male; Mice; Phenobarbital; Phenytoin; Propafenone; Valproic Acid | 2016 |
Factors influencing topiramate clearance in adult patients with epilepsy: A population pharmacokinetic analysis.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fructose; Humans; Male; Middle Aged; Models, Biological; Oxcarbazepine; Phenobarbital; Phenytoin; Topiramate; Valproic Acid; Young Adult | 2016 |
The effects of cimetidine chronic treatment on conventional antiepileptic drugs in mice.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Cimetidine; Drug Interactions; Electroshock; Male; Memory, Long-Term; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2016 |
Anti-epileptic drugs and bone loss: Phenytoin reduces pro-collagen I and alters the electrophoretic mobility of osteonectin in cultured bone cells.
Topics: Animals; Anticonvulsants; Blotting, Western; Bone and Bones; Carbamazepine; Cell Line; Collagen Type I; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Fructose; Gene Expression Profiling; Lamotrigine; Levetiracetam; Microscopy, Confocal; Osteoblasts; Osteonectin; Phenytoin; Piracetam; Procollagen; Real-Time Polymerase Chain Reaction; Topiramate; Triazines; Valproic Acid | 2016 |
The effects of co-medications on lamotrigine clearance in Japanese children with epilepsy.
Topics: Adolescent; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Infant, Newborn; Isoxazoles; Japan; Lamotrigine; Levetiracetam; Male; Phenobarbital; Phenytoin; Piracetam; Triazines; Valproic Acid; Young Adult; Zonisamide | 2016 |
Medication prescribing and patient-reported outcome measures in people with epilepsy in Bhutan.
Topics: Adult; Aged; Anticonvulsants; Bhutan; Carbamazepine; Drug Prescriptions; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Patient Reported Outcome Measures; Phenytoin; Quality of Life; Surveys and Questionnaires; Valproic Acid | 2016 |
Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Lamotrigine; Male; Medication Adherence; Middle Aged; Oxcarbazepine; Phenytoin; Proportional Hazards Models; Retrospective Studies; Risk Factors; Taiwan; Topiramate; Triazines; Valproic Acid; Young Adult | 2016 |
Antiepileptic drugs: Impacts on human serum paraoxonase-1.
Topics: Amines; Anticonvulsants; Aryldialkylphosphatase; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Kinetics; Levetiracetam; Phenytoin; Piracetam; Primidone; Turkey; Valproic Acid | 2017 |
Anti-Epileptic Drug Combination Efficacy in an In Vitro Seizure Model - Phenytoin and Valproate, Lamotrigine and Valproate.
Topics: Animals; Anticonvulsants; Drug Combinations; Drug Interactions; Female; Hippocampus; In Vitro Techniques; Lamotrigine; Male; Models, Theoretical; Phenytoin; Rats; Rats, Wistar; Seizures; Treatment Outcome; Triazines; Valproic Acid | 2017 |
Association between antiepileptic drug dose and long-term response in patients with refractory epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistant Epilepsy; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lamotrigine; Longitudinal Studies; Male; Middle Aged; Phenytoin; Retrospective Studies; Time Factors; Treatment Outcome; Triazines; Valproic Acid | 2017 |
The efficacy of different kinds of intravenously applied antiepileptic drugs in the treatment of status epilepticus. How can it be determined?
Topics: Acetamides; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Anticonvulsants; Female; Health Behavior; Humans; Lacosamide; Levetiracetam; Male; Middle Aged; Phenytoin; Piracetam; Retrospective Studies; Status Epilepticus; Treatment Outcome; Valproic Acid | 2017 |
Simultaneous triple therapy for the treatment of status epilepticus.
Topics: Animals; Anticonvulsants; Brain Waves; Combined Modality Therapy; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Male; Maze Learning; Midazolam; Neurons; Phenytoin; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Treatment Outcome; Valproic Acid | 2017 |
Lamotrigine Drug Interactions in Combination Therapy and the Influence of Therapeutic Drug Monitoring on Clinical Outcomes of Adult Patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Clonazepam; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Fructose; Humans; Lamotrigine; Levetiracetam; Male; Phenytoin; Piracetam; Seizures; Topiramate; Triazines; Valproic Acid | 2017 |
Variable course of Unverricht-Lundborg disease: Early prognostic factors.
Topics: Adolescent; Adult; Age of Onset; Analysis of Variance; Anticonvulsants; Cathepsin B; Electroencephalography; Evoked Potentials, Somatosensory; Female; Humans; Italy; Male; Middle Aged; Phenytoin; Prognosis; Retrospective Studies; Unverricht-Lundborg Syndrome; Valproic Acid; Young Adult | 2017 |
Sotalol enhances the anticonvulsant action of valproate and diphenylhydantoin in the mouse maximal electroshock model.
Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Avoidance Learning; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Electroshock; Epilepsy; Female; Fluorescence Polarization Immunoassay; Mice; Phenytoin; Seizures; Sotalol; Tissue Distribution; Valproic Acid | 2017 |
The effects of felbamate on appetitive and aversive instrumental learning in adult rats.
Topics: Animals; Anticonvulsants; Appetitive Behavior; Avoidance Learning; Carbamazepine; Cognition; Conditioning, Operant; Felbamate; Female; Phenylcarbamates; Phenytoin; Propylene Glycols; Rats; Rats, Sprague-Dawley; Valproic Acid | 2018 |
Treatment outcomes after the introduction of a new seizure management protocol.
Topics: Adult; Anticonvulsants; Clinical Protocols; Drug-Related Side Effects and Adverse Reactions; Emergency Service, Hospital; Female; Humans; Levetiracetam; Male; Middle Aged; Phenobarbital; Phenytoin; Piracetam; Retrospective Studies; Status Epilepticus; Treatment Outcome; Valproic Acid | 2018 |
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Logistic Models; Male; Oxcarbazepine; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Topiramate; Valproic Acid; Young Adult | 2018 |
A cool side effect of valproic acid administration: Single dose-induced hypothermia.
Topics: Adult; Anticonvulsants; Humans; Hypothermia; Levetiracetam; Male; Phenytoin; Seizures; Valproic Acid | 2018 |
Regulation of P2X7 receptor function of neural progenitor cells in the hippocampal subgranular zone by neuronal activity in the dentate gyrus.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dentate Gyrus; Female; Gabapentin; Male; Mice; Muscimol; N-Methylaspartate; Neural Stem Cells; Neurons; Phenytoin; Receptors, Purinergic P2X7; Tetrodotoxin; Valproic Acid | 2018 |
Influence of dronedarone (a class III antiarrhythmic drug) on the anticonvulsant potency of four classical antiepileptic drugs in the tonic-clonic seizure model in mice.
Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Behavior, Animal; Brain; Carbamazepine; Disease Models, Animal; Dronedarone; Drug Interactions; Male; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2019 |
Fetal antiepileptic drug exposure and learning and memory functioning at 6 years of age: The NEAD prospective observational study.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Humans; Lamotrigine; Learning; Memory; Memory Disorders; Mothers; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prospective Studies; Valproic Acid | 2019 |
A Novel Protocol to Reduce Early Seizures After Cranioplasty: A Single-Center Experience.
Topics: Adult; Anticonvulsants; Clinical Protocols; Decompressive Craniectomy; Drug Administration Schedule; Drug Therapy, Combination; Female; Hospitalization; Humans; Levetiracetam; Male; Phenytoin; Postoperative Complications; Recurrence; Retrospective Studies; Seizures; Skull; Treatment Outcome; Valproic Acid | 2019 |
New derivative of 1,2,4-triazole-3-thione (TP427) potentiates the anticonvulsant action of valproate, but not that of carbamazepine, phenytoin or phenobarbital in the mouse tonic-clonic seizure model.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Male; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2019 |
Effects of Sodium Valproate, Levetiracetam and Phenytoin Therapy on Evoked Potentials in Children with Epilepsy.
Topics: Adolescent; Child; Child, Preschool; Cross-Sectional Studies; Epilepsy; Evoked Potentials; Humans; Levetiracetam; Phenytoin; Valproic Acid | 2019 |
Antiepileptic Drug Treatment Patterns in Women of Childbearing Age With Epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Anxiety Disorders; Comorbidity; Dissociative Disorders; Epilepsies, Partial; Epilepsy, Generalized; Female; Headache Disorders; Humans; Lamotrigine; Levetiracetam; Mental Disorders; Migraine Disorders; Mood Disorders; Oxcarbazepine; Phenytoin; Retrospective Studies; Risk; Teratogens; Topiramate; Valproic Acid; Young Adult | 2019 |
The effect of co-administration of pentylenetetrazole with pilocarpine: New modified PTZ models of kindling and seizure.
Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Drug Resistance; Epilepsy; Kindling, Neurologic; Male; Miotics; Pentylenetetrazole; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Seizures; Valproic Acid | 2019 |
Management and attitudes toward patients with epilepsy in general practice: How far have we come in three decades?
Topics: Adult; Anticonvulsants; Attitude of Health Personnel; Australia; Carbamazepine; Clinical Competence; Electroencephalography; Epilepsy; Female; Follow-Up Studies; General Practitioners; Humans; Lamotrigine; Levetiracetam; Magnetic Resonance Imaging; Male; Middle Aged; Neurology; Phenytoin; Referral and Consultation; Surveys and Questionnaires; Valproic Acid | 2019 |
Estimation of apparent clearance of valproic acid in adult Saudi patients.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Phenytoin; Retrospective Studies; Saudi Arabia; Topiramate; Valproic Acid; Young Adult | 2019 |
Elevated serum alkaline phosphatase in epilepsy: effect of age and treatment.
Topics: Adolescent; Adult; Age Factors; Alkaline Phosphatase; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cohort Studies; Cross-Sectional Studies; Epilepsy; Female; Humans; India; Male; Phenytoin; Seizures; Valproic Acid; Young Adult | 2020 |
The number and kind of antiepileptics affect propofol dose requirement for anesthesia: observational study.
Topics: Anticonvulsants; Humans; Phenobarbital; Phenytoin; Propofol; Valproic Acid | 2020 |
Anti-epileptic drug and folic acid usage during pregnancy, seizure and malformation outcomes: Changes over two decades in the Kerala Registry of Epilepsy and Pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Folic Acid; Humans; India; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenytoin; Pregnancy; Pregnancy Complications; Registries; Seizures; Topiramate; Valproic Acid | 2020 |
Exploring the ameliorative role of α7 neuronal nicotinic acetylcholine receptor modulation in epilepsy and associated comorbidities in post-PTZ-kindled mice.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anticonvulsants; Corticosterone; Depression; Dose-Response Relationship, Drug; Epilepsy; Kindling, Neurologic; Male; Memory Disorders; Mice; Pentylenetetrazole; Phenytoin; Valproic Acid | 2020 |
A Novel Correction Equation Avoids High-Magnitude Errors in Interpreting Therapeutic Drug Monitoring of Phenytoin Among Critically Ill Patients.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Critical Care; Critical Illness; Drug Monitoring; Female; Humans; Hypoalbuminemia; Intensive Care Units; Male; Middle Aged; Phenytoin; Retrospective Studies; Valproic Acid; Young Adult | 2020 |
Pediatric Convulsive Status Epilepticus: Act Fast, No matter With What!
Topics: Child; Double-Blind Method; Humans; Levetiracetam; Phenytoin; Status Epilepticus; Valproic Acid | 2020 |
Second-line anticonvulsants for paediatric convulsive status epilepticus.
Topics: Anticonvulsants; Child; Double-Blind Method; Humans; Levetiracetam; Phenytoin; Status Epilepticus; Valproic Acid | 2020 |
Analytical validation of a quantitative method for therapeutic drug monitoring on the Alinity
Topics: Amikacin; Automation, Laboratory; Colorimetry; Drug Monitoring; Gentamicins; Humans; Immunoassay; Nephelometry and Turbidimetry; Phenobarbital; Phenytoin; Reproducibility of Results; Theophylline; Valproic Acid; Vancomycin | 2020 |
Effects of antiepileptic drugs on electroencephalography (EEG): Insights and applicability.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid; Young Adult | 2020 |
Choosing Anticonvulsant Medications to Manage Status Epilepticus.
Topics: Adult; Anticonvulsants; Disease Management; Drug Therapy, Combination; Epilepsy, Generalized; Female; Humans; Levetiracetam; Midazolam; Phenytoin; Status Epilepticus; Valproic Acid | 2020 |
Antiepileptic combination therapy with Stevens-Johnson syndrome and toxic epidermal necrolysis: Analysis of a Japanese pharmacovigilance database.
Topics: Anticonvulsants; Carbamazepine; Clobazam; Clonazepam; Databases, Factual; Drug Therapy, Combination; Epilepsy; Gabapentin; Humans; Japan; Lacosamide; Lamotrigine; Levetiracetam; Lorazepam; Pharmacovigilance; Phenytoin; Stevens-Johnson Syndrome; Valproic Acid | 2020 |
Anticonvulsant Effectiveness and Neurotoxicity Profile of 4-butyl-5-[(4-chloro-2-methylphenoxy)methyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione (TPL-16) in Mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Male; Mice; Muscle Strength; Phenobarbital; Phenytoin; Rotarod Performance Test; Seizures; Thiones; Triazoles; Valproic Acid | 2021 |
Pharmacodynamic and pharmacokinetic interactions of hydroalcoholic leaf extract of Centella asiatica with valproate and phenytoin in experimental models of epilepsy in rats.
Topics: Adjuvants, Pharmaceutic; Animals; Anticonvulsants; Behavior, Animal; Centella; Cognitive Dysfunction; Cytochrome P-450 Enzyme Inhibitors; Disease Models, Animal; Electroshock; Epilepsy; Glutathione; Herb-Drug Interactions; Malondialdehyde; Medicine, Ayurvedic; Methanol; Oxidative Stress; Pentylenetetrazole; Phenytoin; Plant Extracts; Plant Leaves; Rats, Wistar; Seizures; Valproic Acid | 2021 |
Acute and chronic treatment with moclobemide, a reversible MAO-inhibitor, potentiates the antielectroshock activity of conventional antiepileptic drugs in mice.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Epilepsy; Female; Male; Memory, Long-Term; Mice; Moclobemide; Monoamine Oxidase Inhibitors; Motor Activity; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2021 |
A pharmacokinetic simulation study to assess the performance of a sparse blood sampling approach to quantify early drug exposure.
Topics: Adolescent; Adult; Area Under Curve; Biological Variation, Population; Blood Specimen Collection; Child; Child, Preschool; Computer Simulation; Drug Monitoring; Emergency Treatment; Female; Healthy Volunteers; Humans; Levetiracetam; Male; Middle Aged; Models, Biological; Phenytoin; Valproic Acid; Young Adult | 2021 |
Effects of antiepileptic drugs' administration during pregnancy on the nerve cell proliferation and axonal outgrowth of human neuroblastoma SH-SY5Y nerve cells.
Topics: Anticonvulsants; Carbamazepine; Cell Line, Tumor; Cell Proliferation; Child; Epilepsy; Female; Humans; Lamotrigine; NAV1.1 Voltage-Gated Sodium Channel; Neuroblastoma; Neuronal Outgrowth; Neurons; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Valproic Acid | 2021 |
Monitoring for valproate and phenytoin toxicity in hypoalbuminaemia: A retrospective cohort study.
Topics: Cohort Studies; Humans; Hypoalbuminemia; Phenytoin; Retrospective Studies; Valproic Acid | 2021 |
Post-stroke epilepsy and antiepileptic drug use in men and women.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Medication Adherence; Middle Aged; Phenytoin; Stroke; Sweden; Valproic Acid | 2021 |
Antiseizure Drug Levels in Children Aged 2-12 Years Presenting With Breakthrough Seizures: A Single Center Cross-sectional Study.
Topics: Anticonvulsants; Child; Cross-Sectional Studies; Humans; Pharmaceutical Preparations; Phenytoin; Seizures; Valproic Acid | 2021 |
Post-Traumatic Epilepsy in Zebrafish Is Drug-Resistant and Impairs Cognitive Function.
Topics: Animals; Anticonvulsants; Carbamazepine; Cognitive Dysfunction; Disease Models, Animal; Drug Resistant Epilepsy; Epilepsy, Post-Traumatic; Female; Male; Phenytoin; Valproic Acid; Zebrafish | 2021 |
The effect of antiepileptic drugs on re-myelinization of axons: Phenytoin, levetiracetam, carbamazepine, and valproic acid, used following traumatic brain injury.
Topics: Animals; Anticonvulsants; Axons; Brain Injuries, Traumatic; Carbamazepine; Levetiracetam; Phenytoin; Rats; Rats, Long-Evans; Remyelination; Treatment Outcome; Valproic Acid | 2021 |
Valproate-Induced Pancytopenia and Phenytoin Toxicity in a Young Adult With Intellectual Disability and Mesial Temporal Lobe Sclerosis.
Topics: Humans; Intellectual Disability; Pancytopenia; Phenytoin; Sclerosis; Temporal Lobe; Valproic Acid; Young Adult | 2021 |
An in vitro Study on the Contractility of Epileptic Myometrium and Effects of Antiepileptic Agents on Oxytocin-Induced Contractions of Myometrium Isolated from Absence Epileptic WAG/Rij Rats.
Topics: Animals; Anticonvulsants; Antifibrotic Agents; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Levetiracetam; Myometrium; Oxytocin; Phenytoin; Pregnancy; Rats; Rats, Wistar; Uterine Contraction; Valproic Acid | 2022 |
Clinical Evaluation of Levetiracetam in the Treatment of Epilepsy.
Topics: Anticonvulsants; Epilepsy; Humans; Levetiracetam; Phenytoin; Valproic Acid | 2022 |
Assessment of porphyrogenicity of drugs and chemicals in selected hepatic cell culture models through a fluorescence-based screening assay.
Topics: Cell Culture Techniques; Heme; Hepatocytes; Humans; Liver; Norgestrel; Phenobarbital; Phenytoin; Porphobilinogen Synthase; Porphyrias, Hepatic; Valproic Acid | 2022 |
A Phenytoin-Induced Ataxia Mimicking a Stroke.
Topics: Ataxia; Carbamazepine; Female; Humans; Middle Aged; Phenytoin; Stroke; Valproic Acid | 2022 |
Identification of novel signal of clobazam-associated drug reaction with eosinophilia and systemic symptoms syndrome: A disproportionality analysis.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Clobazam; Drug Hypersensitivity Syndrome; Eosinophilia; Female; Humans; Levetiracetam; Male; Middle Aged; Phenytoin; Valproic Acid; Young Adult | 2022 |
Trimetazidine, an Anti-Ischemic Drug, Reduces the Antielectroshock Effects of Certain First-Generation Antiepileptic Drugs.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Electroshock; Epilepsy; Mice; Phenobarbital; Phenytoin; Trimetazidine; Valproic Acid | 2022 |
Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis.
Topics: Anticoagulants; Humans; Ischemic Stroke; Levetiracetam; Phenytoin; Retrospective Studies; Valproic Acid; Venous Thromboembolism | 2022 |
A pilot study on identifying gene signatures as markers for predicting patient response to antiseizure medications.
Topics: Anticonvulsants; Butyrate Response Factor 1; Carbamazepine; Humans; Peptide Elongation Factors; Phenytoin; Pilot Projects; Poly(A)-Binding Protein I; Protein Serine-Threonine Kinases; Research Design; Transcription Factors; Valproic Acid | 2023 |
Anticonvulsant fatalities reported to the American Association of Poison Control Centers 2000 - 2019.
Topics: Aged; Anticonvulsants; Benzodiazepines; Carbamazepine; Humans; Phenytoin; Poison Control Centers; Retrospective Studies; Suicide; United States; Valproic Acid | 2023 |
Interaction of Varenicline with Classic Antiseizure Medications in the Mouse Maximal Electroshock-Induced Seizure Model.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Humans; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Varenicline | 2023 |
Valproate-related hyperammonemic encephalopathy with generalized suppression EEG: a case report.
Topics: Adult; Anticonvulsants; Brain Diseases; Electroencephalography; Epilepsy; Female; Humans; Hyperammonemia; Neurotoxicity Syndromes; Phenytoin; Valproic Acid | 2023 |
Trends and Differences in Status Epilepticus Treatment of Children and Adults Over 10 Years: A Comparative Study of Medical Records (2012-2021) from a University Hospital in Germany.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Benzodiazepines; Child; Female; Hospitals, University; Humans; Lacosamide; Levetiracetam; Male; Medical Records; Midazolam; Middle Aged; Phenobarbital; Phenytoin; Propofol; Status Epilepticus; Valproic Acid | 2023 |