Compounds > phenytoin

phenytoin and troleandomycin

phenytoin has been researched along with troleandomycin in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Baciewicz, AM1
Andrews, F; Brenner, M; Ellis, EF; Jusko, WJ; Rose, JQ; Spector, SL; Szefler, SJ; Yurchak, AM1
Hanssen, BR; Lindstrom, TD; Wrighton, SA1
Ariyama, J; Furuno, H; Hirai, K; Koyama, J; Shimada, H; Simamura, E1
Marks, B; Raucy, J; Trubetskoy, O; Yueh, MF; Zielinski, T1

Reviews

1 review(s) available for phenytoin and troleandomycin

ArticleYear
Carbamazepine drug interactions.
    Therapeutic drug monitoring, 1986, Volume: 8, Issue:3

    Topics: Carbamazepine; Cimetidine; Dextropropoxyphene; Drug Interactions; Erythromycin; Humans; Isoniazid; Lithium; Phenobarbital; Phenytoin; Primidone; Protein Binding; Troleandomycin; Valproic Acid; Warfarin

1986

Other Studies

8 other study(ies) available for phenytoin and troleandomycin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Steroid-specific and anticonvulsant interaction aspects of troleandomycin-steroid therapy.
    The Journal of allergy and clinical immunology, 1982, Volume: 69, Issue:5

    Topics: Asthma; Dose-Response Relationship, Drug; Drug Interactions; Humans; Methylprednisolone; Phenobarbital; Phenytoin; Prednisolone; Troleandomycin

1982
Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Cytochrome P-450 Enzyme System; Dexamethasone; Erythromycin; Humans; In Vitro Techniques; Macrolides; Male; Microsomes, Liver; NADP; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Troleandomycin

1993
Paraquat detoxicative system in the mouse liver postmitochondrial fraction.
    Archives of biochemistry and biophysics, 2002, Jun-01, Volume: 402, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cobalt; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred ICR; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Paraquat; Phenobarbital; Phenytoin; Proadifen; Rabbits; Rifampin; Troleandomycin; Vitamin E

2002
A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.
    The AAPS journal, 2005, Mar-04, Volume: 7, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Chromans; Clotrimazole; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enhancer Elements, Genetic; Enzyme Induction; Genes, Reporter; Genes, Synthetic; Humans; Ketoconazole; Liver Neoplasms; Lovastatin; Luciferases; Mifepristone; Neoplasm Proteins; Nifedipine; Omeprazole; Paclitaxel; Phenytoin; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Thiazolidinediones; Transcription, Genetic; Troglitazone; Troleandomycin

2005