phenytoin and triiodothyronine

phenytoin has been researched along with triiodothyronine in 86 studies

Research

Studies (86)

Timeframe	Studies, this research(%)	All Research%
pre-1990	67 (77.91)	18.7374
1990's	11 (12.79)	18.2507
2000's	1 (1.16)	29.6817
2010's	7 (8.14)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Fichsel, H; Knöpfle, G	1
Aizawa, T; Kawabe, T; Tsukui, T; Yamada, T	1
Ganes, T; Johannessen, SI; Rootwelt, K	1
Hamada, S; Nishimoto, M	1
Liewendahl, K; Majuri, H	1
Helenius, T; Liewendahl, K; Majuri, H	1
Cavalieri, RR; Cruse, K; Gavin, LA; Hammond, ME; Wallace, A	1
Lamberg, BA; Liewendahl, K; Rosengård, S	1
Bates, D; Evered, DC; Heath, A; Howe, JG; Ratcliffe, WA; Schardt, CW; Yeo, PP	1
Pain, RW; Phillips, PJ	1
Heyma, P; Larkins, RG; Perry-Keene, D; Peter, CT; Ross, D; Sloman, JG	1
Hüfner, M; Knöpfle, M	1
Lenz, PH; Toth, JM; Wien, GH	1
Alsever, RN; Rudolph, MC; Stjernholm, MR	1
Boado, RJ; Cageao, LF; Ceppi, JA; Zaninovich, AA	1
Boddaert, A; Chevrier, M; Cordier, A; De Sandro, V; Melcion, C; Richert, L	1
Benson, DM; Goussis, OS; Pappolla, MA; Theodoropoulos, TJ; Zolman, JC	1
Schröder-van der Elst, JP; van der Heide, D	1
Marshall, LF; Morrissey, EC; Ziegler, MG	1
Beastall, GH; Brodie, MJ; Larkin, JG; Macphee, GJ	1
Barlow, JW; Kolliniatis, E; Lim, CF; Stockigt, JR; Topliss, DJ	1
Braverman, LE; Moring, AF; Rajatanavin, R; Young, RA	1
Weissel, M	1
Biezunski, DR; Shapiro, LE; Surks, MI; Zemel, LR	1
Bai, Y; Barlow, JW; Lim, CF; Stockigt, JR; Topliss, DJ	1
Ceppi, JA; Zaninovich, AA	1
Barańska, H; Frank-Piskorska, A; Konieczna, M	1
Davis, JR; Docherty, K; Franklyn, JA; Lynam, TC; Sheppard, MC	1
Davis, JR; Franklyn, JA; Ramsden, DB; Sheppard, MC	1
Tuttlebee, JW	1
György, I; Ilyés, I; Kirilina, S; Tornai, A	1
Gingrich, SA; Shapiro, LE; Smith, PJ; Surks, MI	1
Faber, J; Friis, T; Jørgensen, PH; Kirkegaard, C; Lumholtz, IB; Poulsen, S; Siersbaek-Nielsen, K	1
Helenius, T; Liewendahl, K; Majuri, H; Tikanoja, S	1
Davis, PJ; Gregerman, RI; Handwerger, BS	1
Besser, GM; Chan, V; Landon, J	1
Gharib, H; Munoz, JM	1
Chan, V	1
Hesch, RD; Hüfner, M	1
Oppenheimer, JH	1
Elliott, WJ; Hagen, GA	1
Hansen, JM; Kirkegaard, C; Lauridsen, UB; Siersbaek-Nielsen, K; Skovsted, L	1
Friis, T; Hansen, MJ; Kolendorf, K; Siersbaek-Nielsen, K	1
Pedersen, KO	1
Nicoloff, JT	1
Gharib, H; Mayberry, WE; Ryan, RJ	1
Selye, H	1
Demura, H; Sakurada, T; Tayama, S; Yamaguchi, T; Yamamoto, M	1
Esteban, A; Giménez-Roldán, S	1
Davis, PJ; Handwerger, BS	1
Demura, R; Saito, S; Sakurada, T; Yamaguchi, T; Yamamoto, M	1
Ezrin, C; Farach, H; Volpé, R; Zaninovich, AA	1
Bayley, TA; Higgins, HP; James, W; Row, VV; Vidal, R	1
Ezrin, C; Volpe, R; Zaninovich, AA	1
Hao, YL; Tabachnick, M	1
Degrossi, O; Pecorini, V; Zaninovich, AA	1
Smith, PJ; Surks, MI	2
Wenzel, KW	1
Braverman, LE; Rajatanavin, R; Young, RA	1
Mann, DN; Surks, MI	1
Kumara-Siri, MH; Mann, DN; Surks, MI	1
Kumara-Siri, MH; Mann, DN; Ordene, KW; Surks, MI	1
Hiraiwa, M; Miyasaka, M; Mori, K; Shimoda, S; Suzuki, H; Suzuki, Y; Yamazaki, N	1
Breitbart, R; Kaplan, MM	1
Blackshear, JL; Napier, JS; Schultz, AL; Stuart, DD	1
Aanderud, S; Aarbakke, J; Sundsfjord, J	1
Azizi, F; Braverman, LE; Fang, SL; Ingbar, SH; Theodoropoulos, T; Vagenakis, AG	1
Kennedy, JA; Lim, CF; Loidl, NM; Stokigt, JR; Topliss, DJ	1
Cai, Z; Liu, XM; Ruan, XZ; Zhu, SQ	1
DeFesi, CR; Surks, MI	1
DiStefano, JJ; Kaptein, E; Schröder-van der Elst, JP; van der Bent, C; van der Heide, D; Visser, TJ	2
Kennedy, JA; Lim, CF; Loidl, NM; Stockigt, JR; Topliss, DJ	1
Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA	1
GARTSIDE, JM; GOOLDEN, AW; JACKSON, DJ; OSORIO, C	1
MURPHY, BE; PATTEE, CJ	1
LEVY, RP; MARSHALL, JS	1
CRISPELL, KR; HARRAH, JD; OLICHNEY, MJ	1
de Rijke, YB; van Toor, H; Visser, TJ; Visser, WE	1

Reviews

6 review(s) available for phenytoin and triiodothyronine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Modification of peripheral thyroid hormone metabolism by drugs]. Acta medica Austriaca, 1988, Volume: 15 Suppl 1 Topics: Amiodarone; Antipyrine; Dexamethasone; Heparin; Humans; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Rifampin; Thiouracil; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1988
Interaction of drugs with thyroid hormone binding sites. Annals of the New York Academy of Sciences, 1973, Nov-26, Volume: 226 Topics: Binding Sites; Blood Proteins; Cell Nucleus; Drug Interactions; Endoplasmic Reticulum; Graves Disease; Humans; Kinetics; Liver; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Thyroid Hormones; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1973
Triiodothyronine (T3) radioimmunoassay. A critical evaluation. Mayo Clinic proceedings, 1972, Volume: 47, Issue:12 Topics: Benzoates; Binding Sites; Cross Reactions; Diet; Ethylmercury Compounds; Evaluation Studies as Topic; Geography; Humans; Hyperthyroidism; Hypothyroidism; Immune Sera; Iodine; North America; Phenytoin; Radioimmunoassay; Sulfides; Thyronines; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1972
Multiple effects of 5,5'-diphenylhydantoin on the thyroid hormone system. Endocrine reviews, 1984,Fall, Volume: 5, Issue:4 Topics: Animals; Enzyme Induction; Humans; Liver; Malate Dehydrogenase; Phenytoin; Pituitary Gland, Anterior; Prospective Studies; Receptors, Cell Surface; Receptors, Thyroid Hormone; Thyroid Hormones; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine	1984
Pharmacological interference with in vitro tests of thyroid function. Metabolism: clinical and experimental, 1981, Volume: 30, Issue:7 Topics: Alpha-Globulins; Diagnostic Errors; Dopamine; Dopamine Antagonists; Estrogens; Female; Glucocorticoids; Histamine Antagonists; Humans; Iodine; Male; Pharmacology; Phenytoin; Protein Binding; Serotonin Antagonists; Somatostatin; Thyroid Diseases; Thyroid Function Tests; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1981

Trials

1 trial(s) available for phenytoin and triiodothyronine

Article	Year
Thyroid hormone levels and protein binding in patients on long-term diphenylhydantoin treatment. Clinical endocrinology, 1977, Volume: 6, Issue:5 Topics: Adult; Aged; Arrhythmias, Cardiac; Depression, Chemical; Female; Humans; Male; Middle Aged; Phenytoin; Protein Binding; Thyrotropin; Thyroxine; Triiodothyronine	1977

Other Studies

79 other study(ies) available for phenytoin and triiodothyronine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Effects of anticonvulsant drugs on thyroid hormones in epileptic children. Epilepsia, 1978, Volume: 19, Issue:4 Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Cholesterol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Primidone; Protein Binding; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine; Valproic Acid	1978
Studies on the mechanism of goitrogenic action of diphenylthiohydantoin. Endocrinology, 1978, Volume: 102, Issue:6 Topics: Animals; Antithyroid Agents; Iodine; Male; Methimazole; Organ Size; Phenytoin; Propylthiouracil; Rats; Thyroid Gland; Thyroxine; Triiodothyronine	1978
Effect of carbamazepine, phenytoin and phenobarbitone on serum levels of thyroid hormones and thyrotropin in humans. Scandinavian journal of clinical and laboratory investigation, 1978, Volume: 38, Issue:8 Topics: Adult; Carbamazepine; Epilepsy; Humans; Phenobarbital; Phenytoin; Radioimmunoassay; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine; Triiodothyronine, Reverse	1978
Inhibitory effect of certain drugs on thyroid hormone binding by human liver cytosol. Acta endocrinologica, 1979, Volume: 92, Issue:2 Topics: Adult; Aged; Blood Proteins; Cytosol; Dinitrophenols; Female; Heparin; Humans; Liver; Male; Phenytoin; Protein Binding; Salicylates; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1979
Thyroxine, triiodothyronine, and thyrotropin in serum during long-term diphenylhydantoin therapy. Scandinavian journal of clinical and laboratory investigation, 1976, Volume: 36, Issue:2 Topics: Adolescent; Adult; Aged; Feedback; Female; Humans; Long-Term Care; Male; Middle Aged; Phenytoin; Pituitary Gland; Pituitary Hormone-Releasing Hormones; Receptors, Cell Surface; Thyroid Function Tests; Thyrotropin; Thyroxine; Triiodothyronine	1976
Thyroid function tests in patients on long-term treatment with various anticonvulsant drugs. Clinical endocrinology, 1978, Volume: 8, Issue:3 Topics: Adolescent; Adult; Carbamazepine; Female; Humans; Male; Middle Aged; Phenytoin; Primidone; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine; Valproic Acid	1978
Serum thyroxine, free T4, triiodothyronine, and reverse-T3 in diphenylhydantoin-treated patients. Metabolism: clinical and experimental, 1979, Volume: 28, Issue:11 Topics: Adult; Humans; Male; Phenytoin; Radioimmunoassay; Radioligand Assay; Thyrotropin; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse	1979
Nuclear binding of triiodothyronine and thyroxine in lymphocytes from subjects with hyperthyroidism, hypothyroidism and resistance to thyroid hormones. Clinica chimica acta; international journal of clinical chemistry, 1978, Feb-01, Volume: 83, Issue:1-2 Topics: Adult; Binding, Competitive; Cell Nucleus; Cells, Cultured; Female; Humans; Hyperthyroidism; Hypothyroidism; Lymphocytes; Male; Phenytoin; Salicylates; Thyroxine; Triiodothyronine	1978
Anticonvulsants and thyroid function. British medical journal, 1978, Jun-17, Volume: 1, Issue:6127 Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine	1978
Letter: Thyroid-function tests in diphenylhydantoin-treated patients. Clinical chemistry, 1976, Volume: 22, Issue:4 Topics: Erythrocytes; Humans; Phenytoin; Thyroid Function Tests; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1976
Pharmacological influences on T4 to T3 conversion in rat liver. Clinica chimica acta; international journal of clinical chemistry, 1976, Nov-01, Volume: 72, Issue:3 Topics: Animals; Dexamethasone; Kinetics; Liver; Phenobarbital; Phenytoin; Rats; Thyroxine; Triiodothyronine	1976
Standardization of incubation time and temperature for eight radioimmunoassays. Clinical chemistry, 1975, Volume: 21, Issue:8 Topics: Aldosterone; Digitoxin; Digoxin; Estradiol; Hormones; Humans; Iodine Radioisotopes; Phenytoin; Radioimmunoassay; Temperature; Testosterone; Thyroxine; Time Factors; Triiodothyronine; Tritium	1975
Thyroid-function tests in diphenylhydantoin-treated patients. Clinical chemistry, 1975, Volume: 21, Issue:10 Topics: Adult; Binding, Competitive; Female; Humans; Male; Phenytoin; Pregnancy; Protein Binding; Seizures; Thyroid Function Tests; Thyrotropin; Thyroxine; Triiodothyronine	1975
Diphenylhydantoin stimulates the intrapituitary conversion of thyroxine to triiodothyronine in the rat. Neuroendocrinology, 1992, Volume: 56, Issue:4 Topics: Animals; Feedback; Male; Phenytoin; Pituitary Gland; Radioimmunoassay; Rats; Rats, Wistar; Thyroxine; Triiodothyronine	1992
Comparison of the effects of propylthiouracil, amiodarone, diphenylhydantoin, phenobarbital, and 3-methylcholanthrene on hepatic and renal T4 metabolism and thyroid gland function in rats. Toxicology and applied pharmacology, 1991, Volume: 111, Issue:2 Topics: Amiodarone; Animals; Body Weight; Cytochrome P-450 Enzyme System; Cytochromes b5; Glucuronosyltransferase; Kidney; Liver; Male; Methylcholanthrene; Microsomes, Liver; Organ Size; Oxygenases; Phenobarbital; Phenytoin; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	1991
Permanent alterations in the hypothalamic-pituitary-thyroid axis in the rat following phenytoin exposure in utero. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1990, Volume: 22, Issue:10 Topics: Animals; Body Weight; Female; Hypothalamo-Hypophyseal System; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	1990
Effects of 5,5'-diphenylhydantoin on thyroxine and 3,5,3'-triiodothyronine concentrations in several tissues of the rat. Endocrinology, 1990, Volume: 126, Issue:1 Topics: Animals; Iodine Radioisotopes; Male; Osmolar Concentration; Phenytoin; Rats; Rats, Inbred Strains; Reference Values; Thyroxine; Tissue Distribution; Triiodothyronine	1990
Catecholamine and thyroid hormones in traumatic injury. Critical care medicine, 1990, Volume: 18, Issue:3 Topics: Adolescent; Adult; Brain Injuries; Burns; Catecholamines; Craniocerebral Trauma; Female; Humans; Male; Middle Aged; Norepinephrine; Phenytoin; Thyroid Hormones; Triiodothyronine; Wounds and Injuries	1990
Thyroid hormone concentrations in epileptic patients. European journal of clinical pharmacology, 1989, Volume: 36, Issue:3 Topics: Anticonvulsants; Carbamazepine; Drug Combinations; Epilepsy; Humans; Phenytoin; Thyrotropin; Thyroxine; Triiodothyronine; Valproic Acid	1989
Uptake of 3,5,3'-triiodothyronine by cultured rat hepatoma cells is inhibitable by nonbile acid cholephils, diphenylhydantoin, and nonsteroidal antiinflammatory drugs. Endocrinology, 1989, Volume: 124, Issue:2 Topics: Aminoisobutyric Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Indocyanine Green; Iopanoic Acid; Kinetics; Liver Neoplasms, Experimental; Oleic Acid; Oleic Acids; Phenytoin; Rats; Sulfobromophthalein; Taurocholic Acid; Triiodothyronine	1989
Fasting induces the generation of serum thyronine-binding globulin in Zucker rats. Endocrinology, 1985, Volume: 116, Issue:4 Topics: Animals; Body Weight; Fasting; Iodine Radioisotopes; Male; Obesity; Phenytoin; Rats; Rats, Mutant Strains; Rats, Zucker; Receptors, Cell Surface; Receptors, Thyroid Hormone; Sodium Salicylate; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1985
5,5'-Diphenylhydantoin decreases the entry of 3,5,3'-triiodo-L-thyronine but not L-thyroxine in cultured GH-producing cells. Acta endocrinologica, 1988, Volume: 117, Issue:3 Topics: Animals; Cell Line; Growth Hormone; Kinetics; Phenytoin; Thyroxine; Triiodothyronine	1988
Drug and fatty acid effects on serum thyroid hormone binding. The Journal of clinical endocrinology and metabolism, 1988, Volume: 67, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Contrast Media; Diuretics; Fatty Acids, Nonesterified; Humans; Oleic Acid; Oleic Acids; Phenytoin; Receptors, Thyroid Hormone; Thyroxine; Triiodothyronine	1988
[Effects of diphenylhydantoin on intrapituitary conversion of T4 to T3 in rats]. Medicina, 1986, Volume: 46, Issue:4 Topics: Animals; Female; Phenytoin; Pituitary Gland; Rats; Rats, Inbred Strains; Thyrotropin; Thyroxine; Triiodothyronine	1986
[Effect of short-term administration of phenytoin on blood serum levels of thyroid hormones]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1987, Feb-23, Volume: 42, Issue:8 Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Humans; Male; Middle Aged; Phenytoin; Thyroxine; Triiodothyronine	1987
Tri-iodothyronine and phenytoin reduce prolactin messenger RNA levels in cultured rat pituitary cells. The Journal of endocrinology, 1986, Volume: 109, Issue:3 Topics: Animals; Cells, Cultured; Cytoplasm; Female; In Vitro Techniques; Phenytoin; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; RNA, Messenger; Transcription, Genetic; Triiodothyronine	1986
Phenytoin and thyroid hormone action. The Journal of endocrinology, 1985, Volume: 104, Issue:2 Topics: Animals; Cell Nucleus; Cells, Cultured; Male; Phenytoin; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone; Triiodothyronine	1985
Free triiodothyronine in serum in relation to thyroid function. Medical laboratory sciences, 1985, Volume: 42, Issue:3 Topics: Adult; Female; Humans; Male; Middle Aged; Neoplasms; Phenytoin; Pregnancy; Radioimmunoassay; Thyroid Diseases; Thyroxine-Binding Proteins; Triiodothyronine	1985
Influence of anticonvulsant drugs on thyroid hormones in epileptic children. Acta paediatrica Hungarica, 1985, Volume: 26, Issue:4 Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Humans; Mephenytoin; Phenytoin; Primidone; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1985
5,5'-Diphenylhydantoin (phenytoin) attenuates the action of 3,5,3'-triiodo-L-thyronine in cultured GC cells. Endocrinology, 1985, Volume: 116, Issue:6 Topics: Animals; Cell Division; Cells, Cultured; Growth Hormone; Malate Dehydrogenase; Phenytoin; Pituitary Neoplasms; Rats; Triiodothyronine	1985
The effects of phenytoin (diphenylhydantoin) on the extrathyroidal turnover of thyroxine, 3,5,3'-triiodothyronine, 3,3',5'-triiodothyronine, and 3',5'-diiodothyronine in man. The Journal of clinical endocrinology and metabolism, 1985, Volume: 61, Issue:6 Topics: Aged; Animals; Biotransformation; Diiodothyronines; Female; Humans; Hypothyroidism; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Middle Aged; Phenytoin; Rats; Rats, Inbred Strains; Thyronines; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse	1985
Free thyroxin and free triiodothyronine as measured by equilibrium dialysis and analog radioimmunoassay in serum of patients taking phenytoin and carbamazepine. Clinical chemistry, 1985, Volume: 31, Issue:12 Topics: Adolescent; Adult; Carbamazepine; Dialysis; Female; Humans; Male; Middle Aged; Phenytoin; Radioimmunoassay; Thyrotropin; Thyroxine; Triiodothyronine	1985
Thyroid hormone binding by human serum prealbumin (TBPA). Electrophoretic studies of triiodothyronine-TBPA interaction. The Journal of clinical investigation, 1972, Volume: 51, Issue:3 Topics: Acetamides; Autoradiography; Blood Protein Electrophoresis; Electrophoresis, Disc; Fluorine; Glycolates; Humans; Hydrogen-Ion Concentration; Iodine Isotopes; Male; Phenytoin; Protein Binding; Salicylates; Serum Albumin; Thyroid Function Tests; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1972
Effects of oestrogen on urinary thyrosine excretion. British medical journal, 1972, Dec-23, Volume: 4, Issue:5842 Topics: Adult; Contraceptives, Oral; Estrogens; Ethinyl Estradiol; Female; Humans; Male; Menstruation; Phenytoin; Thyroid Function Tests; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1972
Endocrine manifestations of diphenylhydantoin therapy. Metabolism: clinical and experimental, 1974, Volume: 23, Issue:6 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Alkaline Phosphatase; Blood Glucose; Endocrine System Diseases; Humans; Hydrocortisone; Hydroxylation; Hyperglycemia; Hypocalcemia; Hypothalamus; Kinetics; Metabolic Diseases; Parathyroid Hormone; Phenytoin; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Triiodothyronine	1974
The assay of urinary thyroid hormones for assessing thyroid function. Annals of clinical biochemistry, 1974, Volume: 11, Issue:4 Topics: Adult; Circadian Rhythm; Diagnosis, Differential; Estrogens; Female; Humans; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Male; Phenytoin; Pregnancy; Radioimmunoassay; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1974
A comparison of different compounds for TBG-blocking used in radioimmunoassay for tri-iodothyronine. Clinica chimica acta; international journal of clinical chemistry, 1973, Feb-28, Volume: 44, Issue:1 Topics: Aniline Compounds; Animals; Antigen-Antibody Reactions; Blood Proteins; Buffers; Charcoal; Cross Reactions; Humans; Iodine Isotopes; Phenytoin; Protein Binding; Rabbits; Radioimmunoassay; Salicylates; Serum Albumin; Thyroxine-Binding Proteins; Triiodothyronine	1973
Transport of thyroid hormones in serum and cerebrospinal fluid. The Journal of clinical endocrinology and metabolism, 1973, Volume: 37, Issue:3 Topics: Autoradiography; Chemical Precipitation; Dialysis; Dinitrophenols; Electrophoresis, Polyacrylamide Gel; Humans; Iodine Isotopes; Phenytoin; Sodium Salicylate; Thyroglobulin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1973
The effect of diphenylhydantoin on thyroid function. The Journal of clinical endocrinology and metabolism, 1974, Volume: 39, Issue:4 Topics: Adolescent; Adult; Aged; Female; Humans; Hyperthyroidism; Iodine; Male; Middle Aged; Phenytoin; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine	1974
Evaluation of thyroid status with "effective thyroxine ratio" (E.T.R.). Acta endocrinologica, 1974, Volume: 77, Issue:2 Topics: Adolescent; Adult; Aged; Aspirin; Depression, Chemical; Estrogens; Evaluation Studies as Topic; Female; Humans; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Male; Menopause; Middle Aged; Phenylbutazone; Phenytoin; Pregnancy; Stimulation, Chemical; Sulfadiazine; Sulfathiazoles; Thyroid Function Tests; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1974
A systematic study of variables affecting protein binding of thyroxine and triiodothyronine in serum. Scandinavian journal of clinical and laboratory investigation, 1974, Volume: 34, Issue:3 Topics: Anions; Barbiturates; Buffers; Caffeine; Depression, Chemical; Dialysis; Humans; Hydrogen-Ion Concentration; Iodine Radioisotopes; Methimazole; Osmolar Concentration; Phenytoin; Protein Binding; Salicylates; Temperature; Theophylline; Thyroxine; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine; Ultrafiltration	1974
A new method for the measurement of acute alterations in thyroxine deiodination rate in man. The Journal of clinical investigation, 1970, Volume: 49, Issue:2 Topics: Adrenocorticotropic Hormone; Epinephrine; Humans; Hydrocortisone; Iodine; Iodine Radioisotopes; Methimazole; Methods; Oxytocin; Phenytoin; Potassium Iodide; Prednisolone; Propylthiouracil; Thyrotropin; Thyroxine; Triiodothyronine	1970
Prevention by catatoxic steroids of lithocholic acid-induced biliary concrements in the rat. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 141, Issue:2 Topics: Animals; Bile Acids and Salts; Body Weight; Common Bile Duct; Female; Gallstones; Jaundice; Lithocholic Acid; Liver; Nitriles; Phenobarbital; Phenytoin; Prednisolone; Propionates; Rats; Steroids; Thyroxine; Triamcinolone; Triiodothyronine	1972
[Radioimmunoassay of triiodothyronine]. Nihon Naibunpi Gakkai zasshi, 1972, Nov-20, Volume: 48, Issue:8 Topics: Congenital Hypothyroidism; Dinitrophenols; Humans; Hyperthyroidism; Hypothyroidism; Iodine Isotopes; Methanol; Phenytoin; Radioimmunoassay; Serum Albumin, Bovine; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thyrotropin; Triiodothyronine	1972
Orbicularis oculi "myotonia" in hypothyroid myopathy. European neurology, 1973, Volume: 9, Issue:1 Topics: Cold Temperature; Diazepam; Electromyography; Humans; Hypothyroidism; Male; Middle Aged; Muscle Contraction; Neuromuscular Diseases; Oculomotor Muscles; Phenytoin; Quinine; Triiodothyronine	1973
Thyroid hormone binding in dog plasma. Endocrinology, 1973, Volume: 93, Issue:6 Topics: Binding, Competitive; Blood Proteins; Electrophoresis, Polyacrylamide Gel; Halofenate; Hydrogen-Ion Concentration; Iodine Radioisotopes; Phenytoin; Protein Binding; Serum Albumin; Thyroxine; Triiodothyronine	1973
Radioimmunoassay of triiodothyronine. The Tohoku journal of experimental medicine, 1973, Volume: 110, Issue:4 Topics: Animals; Cross Reactions; Dinitrophenols; Humans; Hyperthyroidism; Hypothyroidism; Imidazoles; Immune Sera; Methanol; Phenytoin; Rabbits; Radioimmunoassay; Serum Albumin, Bovine; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thyroid Hormones; Thyrotropin; Triiodothyronine	1973
Lack of significant binding of L-triiodothyronine by thyroxine-binding globulin in vivo as demonstrated by acute disappearance of 131-I-labeled triiodothyronine. The Journal of clinical investigation, 1966, Volume: 45, Issue:8 Topics: Adolescent; Adult; Aged; Epilepsy; Estrogens; Female; Hepatitis; Humans; Hyperthyroidism; Hypothyroidism; Iodine Isotopes; Liver Cirrhosis; Male; Middle Aged; Myxedema; Phenytoin; Prostatic Neoplasms; Thyroxine-Binding Proteins; Triiodothyronine	1966
The metabolic significance of thyroxine-binding globulin. Studies in a family with decreased thyroxine-binding globulin. Acta endocrinologica, 1969, Volume: 61, Issue:1 Topics: Adolescent; Adult; Aged; Basal Metabolism; Blood Protein Disorders; Child; Epilepsy; Female; Humans; Iodine Radioisotopes; Kinetics; Male; Pedigree; Phenytoin; Sex Chromosomes; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1969
Effects of variations of thyroxine-binding globulin capacity on the disappearance of triiodothyronine from the plasma. The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:12 Topics: Adolescent; Adult; Aged; Anabolic Agents; Binding Sites; Blood Protein Electrophoresis; Blood Proteins; Chromatography, Ion Exchange; Estrogens; Female; Humans; Iodine Radioisotopes; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Phenols; Phenytoin; Protein Binding; Testosterone; Thyroxine; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine	1969
Thyroxine-protein interactions. VII. Effect of thyroxine analogs on the binding of 125-I-thyroxine to highly purified human thyroxine-binding globulin. Endocrinology, 1971, Volume: 88, Issue:1 Topics: Acetates; Butyrates; Chromatography, Ion Exchange; Dialysis; Electrophoresis; Humans; Iodine Isotopes; Phenytoin; Propionates; Protein Binding; Starch; Thyroid Hormones; Thyronines; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1971
Changes in triiodothyronine kinetics produced by variations of serum thyroxine-binding globulin capacity in subjects without thyroxine. The Journal of clinical endocrinology and metabolism, 1971, Volume: 32, Issue:4 Topics: Aged; Female; Humans; Iodine Radioisotopes; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Phenytoin; Protein Binding; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine	1971
Low protein-high carbohydrate diet induces alterations in the serum thyronine-binding proteins in the rat. Endocrinology, 1982, Volume: 110, Issue:5 Topics: Animals; Body Weight; Dietary Carbohydrates; Male; Phenytoin; Protein-Energy Malnutrition; Rats; Rats, Zucker; Receptors, Cell Surface; Receptors, Thyroid Hormone; Thyroxine; Triiodothyronine	1982
5,5'-Diphenylhydantoin decreases specific 3,5,3'-triiodothyronine (T3) binding by rat hepatic nuclear T3 receptors. Endocrinology, 1983, Volume: 112, Issue:5 Topics: Animals; Cell Nucleus; Kinetics; Liver; Male; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Thyroid Hormone; Thyroid Gland; Thyroidectomy; Triiodothyronine	1983
Effect of 5,5'-diphenylhydantoin on the activities of hepatic cytosol malic enzyme and mitochondrial alpha-glycerophosphate dehydrogenase in athyreotic rats. Endocrinology, 1983, Volume: 112, Issue:5 Topics: Animals; Cytosol; Glycerolphosphate Dehydrogenase; Kinetics; Liver; Malate Dehydrogenase; Male; Mitochondria, Liver; Phenytoin; Rats; Rats, Inbred Strains; Thyroidectomy; Triiodothyronine	1983
Diphenylhydantoin inhibits the thyrotropin response to thyrotropin-releasing hormone in man and rat. The Journal of clinical endocrinology and metabolism, 1983, Volume: 56, Issue:5 Topics: Aged; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Female; Humans; Male; Phenytoin; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine	1983
Lowering effect of diphenylhydantoin on serum free thyroxine and thyroxine binding globulin (TBG). Acta endocrinologica, 1984, Volume: 105, Issue:4 Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Male; Phenytoin; Thyroid Function Tests; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1984
Conversion of thyroxine to triiodothyronine in the anterior pituitary gland and the influence of this process on thyroid status. Hormone and metabolic research. Supplement series, 1984, Volume: 14 Topics: Animals; Cerebral Cortex; Iodide Peroxidase; Iodine Radioisotopes; Iopanoic Acid; Liver; Organ Specificity; Peroxidases; Phenytoin; Pituitary Gland, Anterior; Rats; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	1984
Thyroxine replacement requirements in hypothyroid patients receiving phenytoin. Annals of internal medicine, 1983, Volume: 99, Issue:3 Topics: Adult; Drug Administration Schedule; Female; Humans; Hypothyroidism; Phenytoin; Recurrence; Thyrotropin; Thyroxine; Triiodothyronine	1983
Metabolism of thyroid hormones in isolated rat hepatocytes: studies on the influences of carbamazepine and phenytoin. Acta endocrinologica, 1983, Volume: 104, Issue:4 Topics: Animals; Carbamazepine; Cells, Cultured; Liver; Male; Phenytoin; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine	1983
5,5'-Diphenylhydantoin (dilantin) decreases cytosol and specific nuclear 3,5,3'-triiodothyronine binding in rat anterior pituitary in vivo and in cultured GC cells. Endocrinology, 1984, Volume: 115, Issue:1 Topics: Animals; Binding, Competitive; Cell Nucleus; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Kinetics; Male; Phenytoin; Pituitary Gland, Anterior; Pituitary Neoplasms; Rats; Rats, Inbred Strains; Triiodothyronine	1984
Effect of diphenylhydantoin on hypothalamic-pituitary-thyroid function in the rat. The American journal of physiology, 1980, Volume: 239, Issue:6 Topics: Animals; Hypothalamo-Hypophyseal System; Male; Phenytoin; Rats; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine	1980
Effect of loop diuretics and nonsteroidal antiinflammatory drugs on thyrotropin release by rat anterior pituitary cells in vitro. Metabolism: clinical and experimental, 1995, Volume: 44, Issue:8 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Diuretics; Dose-Response Relationship, Drug; Furosemide; Male; Meclofenamic Acid; Phenylacetates; Phenytoin; Pituitary Gland, Anterior; Rats; Rats, Wistar; Thyrotropin; Thyrotropin-Releasing Hormone; Triiodothyronine	1995
Changes of thyroid hormone levels in epileptic patients. Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1994, Volume: 14, Issue:2 Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Phenytoin; Thyrotropin; Thyroxine; Triiodothyronine; Valproic Acid	1994
Normal serum free thyroid hormone concentrations in patients treated with phenytoin or carbamazepine. A paradox resolved. JAMA, 1996, May-15, Volume: 275, Issue:19 Topics: Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Carrier Proteins; Humans; Phenytoin; Seizures; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	1996
Effects of 5, 5'-diphenylhydantoin on the thyroid status in rats. European journal of endocrinology, 1996, Volume: 134, Issue:2 Topics: Animals; Anticonvulsants; Growth Hormone; Liver; Male; Oxygen Consumption; Phenytoin; Pituitary Gland; Rats; Rats, Wistar; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	1996
Drug effects on triiodothyronine uptake by rat anterior pituitary cells in vitro. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 1996, Volume: 104, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cells, Cultured; Diuretics; Enzyme Inhibitors; Flavonoids; Iodide Peroxidase; Iodine Radioisotopes; Male; Phenytoin; Pituitary Gland, Anterior; Rats; Rats, Wistar; Serum Albumin, Bovine; Thyroxine; Triiodothyronine	1996
Effects of 5,5'-diphenylhydantoin on the metabolic pathway of thyroid hormone in rats. European journal of endocrinology, 1997, Volume: 136, Issue:3 Topics: Animals; Feces; Intestinal Mucosa; Kinetics; Male; Phenytoin; Rats; Rats, Wistar; Thyroxine; Triiodothyronine	1997
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR. The Journal of endocrinology, 2000, Volume: 167, Issue:3 Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenase Inhibitors; Diazepam; Female; GABA Modulators; Humans; Iodine Radioisotopes; Leucine; Meclofenamic Acid; Mefenamic Acid; Nifedipine; Nitrendipine; Phenylalanine; Phenytoin; Thyroxine; Triiodothyronine; Tryptophan; Tumor Cells, Cultured; Uterine Neoplasms; Verapamil	2000
Effect of carbon dioxide and diphenylhydantoin on the partition of triiodothy e abelled with iodine-131 between the red cells and the plasma proteins. Nature, 1962, Oct-20, Volume: 196 Topics: Blood Proteins; Carbon Dioxide; Erythrocytes; Humans; Iodine; Phenytoin; Radioisotopes; Serum Globulins; Triiodothyronine	1962
DETERMINATION OF THYROXINE UTILIZING THE PROPERTY OF PROTEIN-BINDING. The Journal of clinical endocrinology and metabolism, 1964, Volume: 24 Topics: Aspirin; Bilirubin; Blood Chemical Analysis; Blood Proteins; Cholesterol; Glucose; Heparin; Hyperthyroidism; Hypothyroidism; Iodides; Iodine; Iodine Isotopes; Mercury; Oxalates; Phenytoin; Potassium; Research; Thyroid Function Tests; Thyroid Hormones; Thyroxine; Triiodothyronine	1964
SHORT-TERM DRUG EFFECTS ON THYROID FUNCTION TESTS. Archives of internal medicine, 1964, Volume: 114 Topics: Iodides; Iodine Isotopes; Pharmacology; Phenytoin; Placebos; Potassium; Propylthiouracil; Thyroid Function Tests; Triiodothyronine	1964
OBSERVATIONS OF THE EFFECT OF ORGANIC DYES AND DIPHENYLHYDANTOIN ON THE IN VITRO BINDING OF RADIOACTIVE 131-I LABELED L-THYROXINE, L-TRIIODOTHYRONINE AND TETRAIODOTHYROACETIC ACID BY HUMAN ERYTHROCYTES AND SERUM PROTEINS. Acta endocrinologica, 1965, Volume: 48 Topics: Blood Protein Electrophoresis; Blood Proteins; Coloring Agents; Electrophoresis; Erythrocytes; Humans; In Vitro Techniques; Iodine; Iodine Isotopes; Metabolism; Pharmacology; Phenytoin; Thyroxine; Triiodothyronine; Trypan Blue	1965
Thyroid status in a large cohort of patients with mental retardation: the TOP-R (Thyroid Origin of Psychomotor Retardation) study. Clinical endocrinology, 2011, Volume: 75, Issue:3 Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Cohort Studies; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Hypothyroidism; Intellectual Disability; Lamotrigine; Linear Models; Male; Middle Aged; Netherlands; Phenobarbital; Phenytoin; Prevalence; Thyroid Gland; Thyrotropin; Thyroxine; Triazines; Triiodothyronine; Valproic Acid	2011