phenytoin and trifluoperazine

phenytoin has been researched along with trifluoperazine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199017 (60.71)18.7374
1990's1 (3.57)18.2507
2000's3 (10.71)29.6817
2010's6 (21.43)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Duffy, EM; Jorgensen, WL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Abraham, MH; Acree, WE; Ibrahim, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Monroe, RR1
Besser, GM; Grossman, A; Rees, LH; Tsagarakis, S1
Cooper, CW; Seitz, PK; Yi, SJ1
Cooper, CW; Seitz, PK1
Drouva, SV; Kordon, C; Laplante, E1
Arnold, K; Gerber, N1
Grinberg, KN; Shapiro, IuL; Vaĭntrub, MIa; Zhurkov, VS1
Bick, M; Fishbein, L1
Trautmann, A1
Frisch, EP; Jones, D; Madden, JS1
Zlotlow, M1
Goulding, R; Kramer, MD; Monroe, RR; Wise, S1
Snyder, S1
Drouva, SV; Epelbaum, J; Kordon, C; Laplante, E1
Erlichman, J; Fleckman, A; Fleischer, N; Schubart, UK1
Chernokhvostov, VV; Freydin, AA; Kosarsky, LS; Lazarev, AV; Saxon, ME1
BARSA, JA; SAUNDERS, JC1

Reviews

3 review(s) available for phenytoin and trifluoperazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Teratogenic and mutagenic effects of anticonvulsive and psychotropic drugs (review of the literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:6

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Antidepressive Agents; Arm; Barbiturates; Chlorpromazine; Chromosome Aberrations; Chromosome Disorders; Cricetinae; Drosophila; Female; Heart Defects, Congenital; Humans; Imipramine; Infant, Newborn; Jaundice, Neonatal; Mutagens; Perphenazine; Phenothiazines; Phenytoin; Pregnancy; Primidone; Rabbits; Thalidomide; Tranquilizing Agents; Trifluoperazine

1972
The interaction of psychopharmacology and psychoanalysis in the borderline patient.
    The Psychiatric quarterly, 1980,Winter, Volume: 52, Issue:4

    Topics: Affect; Anger; Antipsychotic Agents; Borderline Personality Disorder; Chlorpromazine; Clinical Trials as Topic; Depression; Double-Blind Method; Ego; Female; Humans; Imipramine; Lithium; Male; Methods; Personality Disorders; Phenytoin; Procyclidine; Psychoanalytic Interpretation; Tranylcypromine; Trifluoperazine

1980

Trials

2 trial(s) available for phenytoin and trifluoperazine

ArticleYear
Anticonvulsants in the treatment of aggression.
    The Journal of nervous and mental disease, 1975, Volume: 160, Issue:2-1

    Topics: Adult; Aggression; Anticonvulsants; Chlordiazepoxide; Chlorpromazine; Drug Therapy, Combination; Epilepsy; Humans; Impulsive Behavior; Male; Mental Disorders; Neurocognitive Disorders; Phenytoin; Primidone; Schizophrenia; Trifluoperazine; Violence

1975
The interaction of psychopharmacology and psychoanalysis in the borderline patient.
    The Psychiatric quarterly, 1980,Winter, Volume: 52, Issue:4

    Topics: Affect; Anger; Antipsychotic Agents; Borderline Personality Disorder; Chlorpromazine; Clinical Trials as Topic; Depression; Double-Blind Method; Ego; Female; Humans; Imipramine; Lithium; Male; Methods; Personality Disorders; Phenytoin; Procyclidine; Psychoanalytic Interpretation; Tranylcypromine; Trifluoperazine

1980

Other Studies

24 other study(ies) available for phenytoin and trifluoperazine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Involvement of calmodulin in depolarization-induced release of corticotrophin-releasing hormone-41 from the rat hypothalamus in vitro.
    Journal of molecular endocrinology, 1991, Volume: 7, Issue:1

    Topics: Animals; Calcimycin; Calcium; Calmodulin; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Hypothalamus; In Vitro Techniques; Membrane Potentials; Phenytoin; Potassium Chloride; Radioimmunoassay; Rats; Trifluoperazine; Verapamil; Veratridine

1991
Inhibition by phenytoin of in vitro secretion of calcitonin from rat thyroid glands and cultured rat C cells.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1988, Volume: 3, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcitonin; Calcium; Cells, Cultured; In Vitro Techniques; Nitrendipine; Phenytoin; Rats; Reference Values; Thyroid Gland; Thyroid Neoplasms; Trifluoperazine

1988
Cosecretion of calcitonin and calcitonin gene-related peptide from cultured rat medullary thyroid C cells.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1989, Volume: 4, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcitonin; Calcitonin Gene-Related Peptide; Neuropeptides; Nitrendipine; Phenytoin; Phorbol Esters; Rats; Thyroid Neoplasms; Trifluoperazine; Tumor Cells, Cultured; Vasodilator Agents

1989
Progesterone-induced LHRH release in vitro is an estrogen--as well as Ca++- and calmodulin-dependent secretory process.
    Neuroendocrinology, 1985, Volume: 40, Issue:4

    Topics: Animals; Calcium; Calmodulin; Castration; Culture Techniques; Estradiol; Female; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Ion Channels; Phenytoin; Progesterone; Rats; Rats, Inbred Strains; Tetrodotoxin; Trifluoperazine

1985
The effect of diphenyl-piperazine compounds and other agents on diphenylhydantoin, zoxazolamine and hexobarbital metabolism.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 164, Issue:1

    Topics: Animals; Benzopyrenes; Cyclizine; DDT; Diphenhydramine; Endoplasmic Reticulum; Hexobarbital; Humans; Hydroxyzine; Liver; Male; Meclizine; Methylcholanthrene; Mice; Microscopy, Electron; Phenethylamines; Phenobarbital; Phenytoin; Piperazines; Trifluoperazine; Zoxazolamine

1968
Effect of certain drugs and environmental agents on microsomal enzyme systems.
    The Science of the total environment, 1972, Volume: 1, Issue:2

    Topics: Aminopyrine N-Demethylase; Animals; Anisoles; Aspirin; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Intestine, Small; Kidney; Lung; Male; Microsomes; Microsomes, Liver; Morphinans; Nitro Compounds; Oxidoreductases, N-Demethylating; Phenacetin; Phenanthrenes; Phenobarbital; Phenytoin; Rats; Transferases; Trifluoperazine

1972
[Dialysis of drugs and poisons. 2].
    Medizinische Klinik, 1972, Nov-03, Volume: 67, Issue:44

    Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine

1972
Chlormethiazole and trifluoperazine in alcohol withdrawal.
    The British journal of psychiatry : the journal of mental science, 1969, Volume: 115, Issue:527

    Topics: Alcoholism; Chlormethiazole; Coma; Depression; Feeding and Eating Disorders; Female; Headache; Humans; Liver Function Tests; Male; Methaqualone; Nausea; Phenytoin; Sleep; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Trifluoperazine

1969
Temporal lobe "spike focus" associated with confusion, complete amnesia and fugues in a paranoid schizophrenic.
    The Psychiatric quarterly, 1968, Volume: 42, Issue:4

    Topics: Adult; Amnesia; Chlorpromazine; Cognition Disorders; Dissociative Disorders; Electroencephalography; Epilepsy, Temporal Lobe; Humans; Male; Paranoid Disorders; Phenobarbital; Phenytoin; Schizophrenia; Time Factors; Trifluoperazine

1968
EFG activation of patients receiving phenothiazines and chlordiazepoxide.
    The Journal of nervous and mental disease, 1965, Volume: 141, Issue:1

    Topics: Adult; Anxiety; Cerebral Cortex; Chloralose; Chlordiazepoxide; Chlorpromazine; Depression; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Phenothiazines; Phenytoin; Schizophrenia; Trifluoperazine

1965
Calmodulin involvement on the Ca++-dependent release of LHRH and SRIF in vitro.
    Neuroendocrinology, 1984, Volume: 38, Issue:3

    Topics: Animals; Calcimycin; Calcium; Calmodulin; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; In Vitro Techniques; Male; Phenytoin; Potassium; Rats; Rats, Inbred Strains; Somatostatin; Trifluoperazine; Veratridine

1984
Effect of trifluoperazine, D600, and phenytoin on depolarization- and thyrotropin-releasing hormone-induced thyrotropin release from rat pituitary tissue.
    Endocrinology, 1981, Volume: 108, Issue:6

    Topics: Animals; Calcium; Gallopamil; Ion Channels; Male; Membrane Potentials; Phenytoin; Pituitary Gland, Anterior; Potassium; Rats; Sodium; Thyrotropin; Thyrotropin-Releasing Hormone; Trifluoperazine; Verapamil; Veratridine

1981
Calmodulin-dependent regulation of calcium-activated outward current in frog atrial membrane.
    Advances in myocardiology, 1982, Volume: 3

    Topics: Animals; Calcium; Calcium-Binding Proteins; Calmodulin; Electrocardiography; Heart Atria; Ion Channels; Myocardial Contraction; Phenytoin; Potassium; Rana ridibunda; Trifluoperazine

1982
BENZQUINAMIDE IN THE TREATMENT OF PSYCHOTIC PATIENTS.
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Chlorpromazine; Chlorprothixene; Drug Therapy; Humans; Mental Disorders; Phenytoin; Psychotic Disorders; Quinolizines; Thioridazine; Tranquilizing Agents; Trifluoperazine; Trimeprazine

1964