phenytoin has been researched along with triazoles in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 10 (47.62) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Holland, JT; Mitchell, AS | 1 |
| Horiuchi, M; Ibii, N; Yamamoto, K | 1 |
| Hammett, JL; Langenbacher, KM; Marino, MR; Nichola, P; Uderman, HD | 1 |
| Kou, JH; Saha, P | 1 |
| Holopainen, IE; Kivelä, R; Korpi, ER | 1 |
| Eve, MD; Fielding, A; Ghahramani, P; Love, ER; Purkins, L; Wood, N | 1 |
| Curigliano, G; de Braud, F; De Pas, T; Fazio, N; Formica, V; Goldhirsch, A; Pietri, E; Spitaleri, G | 1 |
| Kantesaria, B; Krishna, G; Sansone-Parsons, A | 1 |
| Franklin, MR; Kupferberg, HJ; Schmutz, M; Stables, JP; White, HS; Wolf, HH | 1 |
| Alffenaar, JW; Daenen, SM; Kosterink, JG; Uges, DR; van der Elst, KC | 1 |
| de Hoon, J; Meersseman, P; Meersseman, W; Spriet, I; Willems, L | 1 |
| Deng, XQ; Li, FN; Quan, ZS; Song, MX; Wei, CX | 1 |
| Kleinjans, JC; Pennings, JL; Piersma, AH; Robinson, JF; Theunissen, PT; van Herwijnen, MH | 1 |
| Chen, SC; Dolton, MJ; McLachlan, AJ; Ng, K; Pont, LG; Ray, JE | 1 |
| Chen, SC; Dolton, MJ; McLachlan, AJ; Ng, K; Pont, L; Ray, JE | 1 |
| He, L; Lee, J; Mendell-Harary, J; Tao, B; Walker, J; Wickremasingha, P; Wight, D | 1 |
| DeOrazio, RJ; Fitzpatrick, K; Guo, C; Guzzo, PR; Hu, M; Khmelnitsky, Y; Kitchen, DB; Liu, S; Luche, M; Maeng, JH; Mhyre, AJ; Tom, S; Usyatinsky, A; Zhang, Z | 1 |
| Davis, K; Fabian, E; Greenhaw, J; Groeters, S; Herold, M; Kamp, H; Looser, R; Marxfeld, H; Mattes, W; Mellert, W; Moeller, N; Montoya-Parra, G; Prokoudine, A; Strauss, V; van Ravenzwaay, B; Walk, T | 1 |
| Brüggemann, RJ; Burger, DM; Dolton, MJ; McLachlan, AJ | 1 |
| Baker, EM; George, AL; Hawkins, NA; Kearney, JA; Meisler, MH; Patel, MK; Thompson, CH; Wagnon, JL; Wengert, ER | 1 |
| Drabik, M; Florek-Łuszczki, M; Głuszak, M; Jankiewicz, M; Kozińska, J; Plech, T; Plewa, Z; Wróblewska-Łuczka, P; Łuszczki, JJ | 1 |
2 trial(s) available for phenytoin and triazoles
| Article | Year |
|---|---|
Coadministration of voriconazole and phenytoin: pharmacokinetic interaction, safety, and toleration.
Topics: Adult; Anticonvulsants; Antifungal Agents; Drug Combinations; Drug Interactions; Humans; Male; Phenytoin; Pyrimidines; Triazoles; Voriconazole | 2003 |
Drug interaction assessment following concomitant administration of posaconazole and phenytoin in healthy men.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Antifungal Agents; Drug Administration Schedule; Drug Interactions; Humans; Male; Middle Aged; Phenytoin; Polypharmacy; Time Factors; Triazoles | 2007 |
19 other study(ies) available for phenytoin and triazoles
| Article | Year |
|---|---|
Fluconazole and phenytoin: a predictable interaction.
Topics: Antifungal Agents; Drug Interactions; Fluconazole; Humans; Middle Aged; Phenytoin; Triazoles | 1989 |
[Pharmacology of a 1H-1, 2, 4-triazolyl benzophenone derivative (450191-S), a new sleep-inducer (III). Behavioral study on interactions of 450191-S and other drugs in mice].
Topics: Aminopyrine; Animals; Anti-Anxiety Agents; Apomorphine; Behavior, Animal; Benzodiazepines; Central Nervous System; Central Nervous System Agents; Haloperidol; Hypnotics and Sedatives; Imipramine; Male; Mice; Pentylenetetrazole; Phenytoin; Reserpine; Triazoles | 1984 |
The effect of nefazodone on the single-dose pharmacokinetics of phenytoin in healthy male subjects.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Humans; Male; Metabolic Clearance Rate; Phenytoin; Piperazines; Triazoles | 1997 |
Effect of solubilizing excipients on permeation of poorly water-soluble compounds across Caco-2 cell monolayers.
Topics: Alkaloids; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Cimetidine; Diltiazem; Excipients; Furans; Humans; Hydrogen-Ion Concentration; Imidazoles; Intestinal Absorption; Naphthalenes; Phenytoin; Piperidines; Poloxamer; Polyethylene Glycols; Povidone; Propranolol; Solubility; Triazoles | 2000 |
Do antiepileptics phenytoin, carbamazepine, and loreclezole show GABA(A) receptor subtype selectivity in rat brain sections?
Topics: Animals; Anticonvulsants; Autoradiography; Brain; Bridged Bicyclo Compounds, Heterocyclic; Carbamazepine; In Vitro Techniques; Male; Phenytoin; Protein Isoforms; Rats; Rats, Wistar; Receptors, GABA-A; Triazoles | 2001 |
Life-threatening toxic epidermal necrolysis during voriconazole therapy for invasive aspergillosis after chemotherapy.
Topics: Adult; Anticonvulsants; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Breast Neoplasms; Drug Interactions; Humans; Lung Diseases, Fungal; Male; Phenytoin; Pyrimidines; Stevens-Johnson Syndrome; Triazoles; Voriconazole | 2006 |
The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models.
Topics: Administration, Oral; Animals; Anticonvulsants; Disease Models, Animal; Injections, Intraperitoneal; Mice; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Seizures; Severity of Illness Index; Triazoles; Valproic Acid | 2008 |
Phenytoin-induced reduction of voriconazole serum concentration is not compensated by doubling the dosage.
Topics: Anticonvulsants; Antifungal Agents; Area Under Curve; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Phenytoin; Pulmonary Aspergillosis; Pyrimidines; Triazoles; Voriconazole | 2009 |
Increasing the dose of voriconazole compensates for enzyme induction by phenytoin.
Topics: Administration, Oral; Adult; Anticonvulsants; Antifungal Agents; Aspergillosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Interactions; Female; Humans; Phenytoin; Pyrimidines; Triazoles; Voriconazole | 2010 |
Synthesis and anticonvulsant activity of 7-alkoxy-triazolo-[3, 4-b]benzo[d]thiazoles.
Topics: Animals; Anticonvulsants; Benzothiazoles; Carbamazepine; Drug Evaluation, Preclinical; Electroshock; Mice; Motor Activity; Phenytoin; Seizures; Structure-Activity Relationship; Triazoles | 2010 |
Compound-specific effects of diverse neurodevelopmental toxicants on global gene expression in the neural embryonic stem cell test (ESTn).
Topics: Acetaldehyde; Animals; Carbamazepine; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Embryonic Stem Cells; Gene Expression Profiling; Gene Expression Regulation; In Vitro Techniques; Mice; Neural Stem Cells; Neurites; Penicillin G; Phenytoin; Silanes; Toxicity Tests; Triazoles | 2012 |
Multicenter study of voriconazole pharmacokinetics and therapeutic drug monitoring.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antifungal Agents; Australia; Drug Interactions; Drug Monitoring; Female; Glucocorticoids; Humans; Male; Middle Aged; Mitosporic Fungi; Mycoses; Nucleic Acid Synthesis Inhibitors; Phenytoin; Pyrimidines; Retrospective Studies; Rifampin; Treatment Outcome; Triazoles; Voltage-Gated Sodium Channel Blockers; Voriconazole | 2012 |
Multicenter study of posaconazole therapeutic drug monitoring: exposure-response relationship and factors affecting concentration.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Australia; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Female; Fungi; Humans; Logistic Models; Male; Metoclopramide; Middle Aged; Mycoses; Phenytoin; Ranitidine; Retrospective Studies; Rifampin; Triazoles | 2012 |
Lack of effect of colesevelam HCl on the single-dose pharmacokinetics of aspirin, atenolol, enalapril, phenytoin, rosiglitazone, and sitagliptin.
Topics: Adolescent; Adult; Allylamine; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Anticonvulsants; Antihypertensive Agents; Area Under Curve; Aspirin; Atenolol; Colesevelam Hydrochloride; Dose-Response Relationship, Drug; Drug Interactions; Enalapril; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Phenytoin; Pyrazines; Rosiglitazone; Sitagliptin Phosphate; Thiazolidinediones; Tissue Distribution; Triazoles; Young Adult | 2014 |
The design and synthesis of novel SGLT2 inhibitors: C-glycosides with benzyltriazolopyridinone and phenylhydantoin as the aglycone moieties.
Topics: Dose-Response Relationship, Drug; Drug Design; Glycosides; Humans; Molecular Structure; Phenytoin; Pyridones; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Structure-Activity Relationship; Triazoles | 2014 |
Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma.
Topics: Animals; Atropine; Captopril; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Flutamide; Lamivudine; Liver; Male; Mannitol; Metabolomics; Methotrexate; Neomycin; Oxidative Stress; Phenytoin; Piperazines; Propylthiouracil; Rats; Rats, Wistar; Streptomycin; Triazoles; Valproic Acid; Vancomycin; Zidovudine | 2014 |
Understanding variability in posaconazole exposure using an integrated population pharmacokinetic analysis.
Topics: Adult; Anti-HIV Agents; Anticonvulsants; Antiemetics; Antifungal Agents; Biological Availability; Carbamates; Drug Interactions; Drug Therapy, Combination; Furans; Healthy Volunteers; Humans; Metoclopramide; Nucleic Acid Synthesis Inhibitors; Organophosphates; Phenytoin; Proton Pump Inhibitors; Rifampin; Sulfonamides; Triazoles | 2014 |
The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy.
Topics: Action Potentials; Animals; Anticonvulsants; Brain Diseases; Disease Models, Animal; Drug Administration Schedule; Electroshock; Epilepsy; Female; Hippocampus; Humans; Male; Mice; Mice, Transgenic; Mutation; NAV1.6 Voltage-Gated Sodium Channel; Neurons; Off-Label Use; Phenytoin; Pyridines; Triazoles | 2018 |
Anticonvulsant Effectiveness and Neurotoxicity Profile of 4-butyl-5-[(4-chloro-2-methylphenoxy)methyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione (TPL-16) in Mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Male; Mice; Muscle Strength; Phenobarbital; Phenytoin; Rotarod Performance Test; Seizures; Thiones; Triazoles; Valproic Acid | 2021 |