phenytoin has been researched along with topiramate in 97 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.03) | 18.7374 |
| 1990's | 11 (11.34) | 18.2507 |
| 2000's | 34 (35.05) | 29.6817 |
| 2010's | 41 (42.27) | 24.3611 |
| 2020's | 10 (10.31) | 2.80 |
| Authors | Studies |
|---|---|
| Dodgson, SP; Gardocki, JF; Maryanoff, BE; Nortey, SO; Shank, RP | 1 |
| Costanzo, MJ; Greco, MN; Maryanoff, BE; Nortey, SO; Ortegon, MP; Schupsky, JJ; Shank, RP; Vaught, JL | 1 |
| Anger, T; Madge, DJ; Mulla, M; Riddall, D | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Cheikh, KE; Dogné, JM; Masereel, B; Montero, JL; Scozzafava, A; Supuran, CT; Thiry, A; Vullo, D; Winum, JY | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Huber, VJ; Kwee, IL; Nakada, T; Tsujita, M | 1 |
| Dogné, JM; Frankart, A; Masereel, B; Rolin, S; Scozzafava, A; Supuran, CT; Thiry, A; Vullo, D; Wouters, J | 1 |
| Verkman, AS; Yang, B; Zhang, H | 1 |
| Brenneman, D; Cuyckens, F; Finley, MF; Herb, M; Huang, Y; Iannucci, R; Klein, B; Leclercq, L; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Brenneman, DE; Finley, MF; Herb, M; Klein, BD; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS; Wilcox, KS | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Bourgeois, BF | 1 |
| Fincham, R; Karim, R; Kramer, L; Penry, J; Pledger, G; Privitera, M; Reife, R | 1 |
| Edmonds, HL; Jiang, YD; Shank, RP; Zhang, PY | 1 |
| Vossler, DG; Wyler, AR | 1 |
| Curry, WJ; Kulling, DL | 1 |
| Bazil, CW; Pedley, TA | 1 |
| Luer, MS; Winkler, SR | 1 |
| Anderson, GD | 1 |
| Ebert, U; Löscher, W; Reissmüller, E | 1 |
| Bukhari, AA; McLean, MJ; Wamil, AW | 1 |
| Coulter, DA; DeLorenzo, RJ; Sombati, S | 1 |
| Brodie, MJ; Sills, GJ; Stephen, LJ | 1 |
| Harden, CL | 1 |
| Janowsky, DS | 1 |
| Jagoda, A; Yoon, Y | 1 |
| Belmaker, RH; Einat, H; Shaldubina, A; Shimon, H; Szechtman, H | 1 |
| Albani, F; Avoni, P; Baruzzi, A; Contin, M; Riva, R | 1 |
| Bialer, M; Bishop, FE; Curtin, CR; Doose, DR; Gisclon, LG; Kunze, KL; Levy, RH; Mather, GG; Roskos, LK; Sachdeo, RC; Sachdeo, SK; Shen, DD; Streeter, AJ; Thummel, KE; Trager, WF | 1 |
| Bergin, AM; Connolly, M | 1 |
| Angehagen, M; Ben-Menachem, E; Hansson, E; Rönnbäck, L | 1 |
| Annovazzi, PO; Colombo, B; Comi, G | 1 |
| Gau, CS; Lin, CJ; Liou, HH; Shyu, MK; Wu, SP | 1 |
| Bittigau, P; Dzietko, M; Glier, C; Ikonomidou, C; Jarosz, B; Korobowicz, E | 1 |
| Yatham, LN | 1 |
| Andreula, C; Anna, P; Buttiglione, M; Cosma, A; Lucia, M; Margari, L; Maura, B; Patrizia, V; Perniola, T; Presicci, A; Tommaso, P; Ventura, P | 1 |
| Zenkov, LR | 1 |
| Baumann, RJ; Cook, AM; Farzam, F; Kuhn, RJ; Lewis, DA; Taylor, LM | 1 |
| Crofoot, K; Filtz, TM; Rodriguez-Proteau, R; von Borstel Smith, M | 1 |
| Ago, J; Ishikawa, T; Kamei, C; Matsumoto, N; Murakami, A; Takechi, K | 1 |
| Takahashi, Y | 1 |
| Mazoit, JX; Navarro, V | 1 |
| Hamaguchi, T; Kanehara, S; Matsumoto, T; Motomura, E; Nakagawa, M; Ohoyama, K; Okada, M; Shiroyama, T; Sugiura, Y; Suzuki, D; Tanii, H; Yamamura, S | 1 |
| Bourin, M; Chenu, F; Hascoët, M | 1 |
| Arif, H; Bazil, CW; Buchsbaum, R; Hirsch, LJ; Pierro, J; Resor, SR; Sims, J; Whalen, M | 1 |
| Akiyama, T; Otsubo, H | 1 |
| Faught, E; Hulihan, J; Krumholz, A; Mao, L; Naritoku, D; Privitera, M; Ramsay, E; Schwarzman, L; Wiegand, F | 1 |
| Kim, SE; Kim, SH; Kwon, OY; No, SK; Park, KM | 1 |
| Lang, SY; Shi, XB; Tian, HJ; Wang, RF; Wang, XQ; Yang, F | 1 |
| Gulati, S; Lodha, R; Raj, D | 1 |
| Aldana, BI; Chiu, LM; Guarneros, A; Sanchez-Tafolla, BM; Sitges, M | 1 |
| Phinney, KW; Tai, SS; Yeh, CY | 1 |
| Kotov, AS; Rudakova, IG | 1 |
| Capuzzi, DM; Chervoneva, I; Mintzer, S; Pequinot, E; Rankin, SJ; Skidmore, CT; Sperling, MR | 1 |
| Aichner, HF; Casillas-Villamor, A; Esteban-Fernández, J; Fernández-de Orueta, L; Rodríguez-Álvarez, S | 1 |
| Imai, K; Inoue, K; Inoue, Y; Itoh, K; Kagawa, Y; Mishima, N; Takahashi, Y; Yamamoto, Y; Yazawa, R | 1 |
| Tanaka, S; Tanaka, T | 1 |
| Florek-Luszczki, M; Luszczki, JJ; Wlaz, A | 1 |
| Chowdhury, AH; Chowdhury, RN; Ghose, SK; Habib, M; Haque, B; Hasan, AT; Hoque, A; Khan, SU; Mohammad, QD; Mondal, BA; Rahman, KM | 1 |
| Deeb, S; Logan, BK; McKeown, DA; Scott, KS; Torrance, HJ; Wylie, FM | 1 |
| Afrikanova, T; Buenafe, OE; Crawford, AD; De Prins, A; de Witte, PA; Esguerra, CV; Kaminski, RM; Langlois, M; Leclercq, K; Rospo, CC; Smolders, I; Van Eeckhaut, A | 1 |
| Kagiava, A; Karlovasitou, A; Kimiskidis, VK; Kosmidis, EK; Krikonis, K; Spilioti, M; Zafeiridou, G | 1 |
| Babu, KM; Broach, J; Gleeson, TP; Griswold, MK | 1 |
| Bae, EK; Jang, IJ; Kim, TJ; Lee, J; Lee, KJ; Lee, SK; Moon, J; Shin, D; Shin, JW; Shin, YW | 1 |
| Fuller, HR; Garton, M; Wilson, EL | 1 |
| Chervoneva, I; Miller, R; Mintzer, S; Nei, M; Shah, K; Skidmore, C; Sperling, MR | 1 |
| Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS | 1 |
| Hsieh, CY; Huang, CW; Lai, EC; Lin, SJ; Setoguchi, S; Su, CC; Yang, YK | 1 |
| Ikeda, A; Ito, S; Matsubara, K; Sugimoto, M; Takeuchi, M; Yamamoto, S; Yano, I; Yonezawa, A | 1 |
| Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J | 2 |
| Agier, MS; Beau-Salinas, F; Bejan-Angoulvant, T; Bouquet, E; Jonville-Béra, AP; Simon, C; Vrignaud, L | 1 |
| Brozmanova, H; Grundmann, M; Kacirova, I; Koristkova, B | 1 |
| Battaglia, A; Carey, JC; Ho, KS; Lortz, A; Markham, LM; Newcomb, T; Olson, LM; Sheng, X; Twede, H; Wassman, ER; Weng, C | 1 |
| Bermejo, PE; Gibbs, AA; Huberfeld, G; Kälviäinen, R; Shorvon, SD | 1 |
| Battino, D; Bonizzoni, E; Craig, J; Lindhout, D; Perucca, E; Sabers, A; Thomas, SV; Tomson, T; Vajda, F | 1 |
| Ahmed, SI; Laghari, AA; Qadeer, N; Shamim, MS | 1 |
| Faught, E; Fishman, J; Kalilani, L; Kim, H; Thurman, DJ | 1 |
| Alandas, N; Alqahtani, S; Alsultan, A | 1 |
| A S, R; Baishya, J; Jose, M; Keni, RR; Sankara Sarma, P; Thomas, SV | 1 |
| Bridgewater, B; Feng, S; McIntire, G; Strickland, EC | 1 |
| Ahn, KM; Chung, SJ; Oh, JH; Park, HW; Shim, JS | 1 |
| Adamovich-Zeitlin, RH; Camp, EJ; Gross, RE; Jobst, BC; Kahana, MJ; Lega, BC; MacKenzie, TA; Meisenhelter, S; Quon, RJ; Song, Y; Sperling, MR; Steimel, SA; Testorf, ME | 1 |
| Cai, M; Guo, X; Han, Y; Lin, W; Yang, J; Zhong, R | 1 |
| Agrawal, M; Dhurandhar, Y; Panda, SP | 1 |
| Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T | 1 |
| García-Peñas, JJ; González-Alguacil, E; Soto-Insuga, V | 1 |
| Adab, N; Bluett-Duncan, M; Bromley, R; Christensen, J; Clayton-Smith, J; Edwards, K; Greenhalgh, J; Hill, RA; Jackson, CF; Khanom, S; Marson, AG; McGinty, RN; Pulman, J; Tudur Smith, C | 1 |
27 review(s) available for phenytoin and topiramate
| Article | Year |
|---|---|
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Sodium Channel Blockers; Sodium Channels; Stroke | 2001 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug interaction profile of topiramate.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Male; Phenytoin; Topiramate; Treatment Outcome; Valproic Acid | 1996 |
Recent advancements in epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Neurosurgery; Phenylcarbamates; Phenytoin; Pia Mater; Propylene Glycols; Temporal Lobe; Topiramate; Triazines; Vigabatrin | 1997 |
Newer antiepileptic drugs: gabapentin, lamotrigine, felbamate, topiramate and fosphenytoin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines | 1998 |
Advances in the medical treatment of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin | 1998 |
Antiepileptic drug review: part 2.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Drug Interactions; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines | 1998 |
A mechanistic approach to antiepileptic drug interactions.
Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 1998 |
Therapeutic safety monitoring: what to look for and when to look for it.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2000 |
New treatments of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Olanzapine; Phenytoin; Pirenzepine; Topiramate; Treatment Outcome; Triazines | 1999 |
New antiepileptic drugs and preparations.
Topics: Acetates; Administration, Rectal; Age Factors; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diazepam; Drug Overdose; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines; Valproic Acid | 2000 |
New antiepileptic drug therapies.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Phenytoin; Piracetam; Propylene Glycols; Thiazines; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2002 |
Neuropathic cranial pain.
Topics: Acetates; Amines; Analgesics; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Fructose; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Lamotrigine; Nervous System Diseases; Phenytoin; Topiramate; Triazines | 2003 |
Newer anticonvulsants in the treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Depressive Disorder; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2004 |
[Neuromuscular disorders caused by adverse effects of antiepileptics].
Topics: Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Neuromuscular Diseases; Phenobarbital; Phenytoin; Topiramate; Valproic Acid; Zonisamide | 2007 |
[Drugs for status epilepticus treatment].
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Fructose; Humans; Hypnotics and Sedatives; Levetiracetam; Phenytoin; Piracetam; Propofol; Status Epilepticus; Topiramate; Valproic Acid | 2009 |
[Antiepileptic drugs in North America].
Topics: Anticonvulsants; Carbamazepine; Drug Approval; Fructose; Humans; Japan; Lamotrigine; Levetiracetam; Lorazepam; North America; Phenytoin; Piracetam; Topiramate; Triazines | 2010 |
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy.
Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide | 2016 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Antiepileptic drug treatment of generalized tonic-clonic seizures: An evaluation of regulatory data and five criteria for drug selection.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Drug and Narcotic Control; Drug-Related Side Effects and Adverse Reactions; Humans; Lamotrigine; Levetiracetam; Nitriles; Phenytoin; Pyridones; Seizures; Topiramate; Treatment Outcome | 2018 |
Choice of therapeutic anti-seizure medication in patients with brain tumour.
Topics: Anticonvulsants; Brain Neoplasms; Drug Therapy, Combination; Epilepsy; Gabapentin; Glioma; Humans; Lamotrigine; Levetiracetam; Neoplasm Grading; Phenytoin; Survival Rate; Topiramate; Valproic Acid; Zonisamide | 2019 |
Side effects of long-term oral anti-seizure drugs on thyroid hormones in patients with epilepsy: a systematic review and network meta-analysis.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Topiramate; Valproic Acid | 2022 |
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches.
Topics: Anticonvulsants; Carbamazepine; Dementia; Epilepsy; Felbamate; Gabapentin; Humans; Inflammasomes; Lamotrigine; Mitophagy; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxcarbazepine; Parkinson Disease; Phenytoin; Seizures; Topiramate; Triazines; Ubiquitin-Protein Ligases; Valproic Acid | 2022 |
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide | 2022 |
[Paediatric status epilepticus].
Topics: Adult; Anesthetics; Anticonvulsants; Benzodiazepines; Child; Epilepsy; Humans; Ketamine; Lacosamide; Levetiracetam; Lidocaine; Phenobarbital; Phenytoin; Propofol; Seizures; Status Epilepticus; Topiramate; Valproic Acid | 2022 |
Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child.
Topics: Child; Cohort Studies; Epilepsy; Female; Humans; Lamotrigine; Male; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Topiramate | 2023 |
4 trial(s) available for phenytoin and topiramate
| Article | Year |
|---|---|
Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 600-, 800-, and 1,000-mg daily dosages. Topiramate YE Study Group.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carboplatin; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Fructose; Headache; Humans; Male; Middle Aged; Nervous System Diseases; Phenytoin; Safety; Topiramate; Treatment Outcome | 1996 |
Topiramate in refractory epilepsy: a prospective observational study.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Anticonvulsants; Carbamazepine; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Prospective Studies; Topiramate; Treatment Outcome; Triazines | 2000 |
Topiramate therapeutic monitoring in patients with epilepsy: effect of concomitant antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Phenobarbital; Phenytoin; Prospective Studies; Topiramate; Triazines; Valproic Acid | 2002 |
Efficacy, tolerability, and safety of rapid initiation of topiramate versus phenytoin in patients with new-onset epilepsy: a randomized double-blind clinical trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anticonvulsants; Child; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Emergency Medical Services; Epilepsy; Female; Fructose; Humans; Male; Middle Aged; Phenytoin; Recurrence; Risk Factors; Topiramate; Treatment Outcome | 2010 |
66 other study(ies) available for phenytoin and topiramate
| Article | Year |
|---|---|
Anticonvulsant O-alkyl sulfamates. 2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate and related compounds.
Topics: Animals; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Electroshock; Fructose; Kinetics; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Phenytoin; Seizures; Structure-Activity Relationship; Topiramate | 1987 |
Structure-activity studies on anticonvulsant sugar sulfamates related to topiramate. Enhanced potency with cyclic sulfate derivatives.
Topics: Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Electroshock; Fructose; Mice; Molecular Conformation; Rats; Seizures; Stereoisomerism; Structure-Activity Relationship; Sulfonic Acids; Topiramate | 1998 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose-thioureido tails.
Topics: Acetazolamide; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Sulfonamides | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Inhibition of aquaporin 4 by antiepileptic drugs.
Topics: Animals; Anticonvulsants; Aquaporin 4; Computer Simulation; Drug Evaluation, Preclinical; Humans; Oocytes; Protein Binding; Thermodynamics; Xenopus | 2009 |
Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation.
Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Central Nervous System; Computer Simulation; Electroshock; Humans; Isoenzymes; Male; Mice; Mice, Inbred Strains; Models, Animal; Models, Chemical; Molecular Structure; Recombinant Proteins; Reproducibility of Results; Seizures; Stereoisomerism; Structure-Activity Relationship | 2008 |
Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides.
Topics: Animals; Anticonvulsants; Aquaporin 4; Biological Transport, Active; Cell Line; Mice; Molecular Structure; Neuroglia; Permeability; Rats; Structure-Activity Relationship; Sulfonamides; Thyroid Gland; Water | 2008 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.
Topics: Amides; Animals; Anticonvulsants; Carbonic Anhydrase II; Cell Line; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Male; Mice; Rats; Sulfonamides; Thiophenes | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).
Topics: Absorption; Amides; Animals; Anticonvulsants; Dioxanes; Dogs; Drug Evaluation, Preclinical; Drug Resistance; Epilepsy; Female; Humans; Male; Mice; Rats; Sulfonamides | 2013 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Anticonvulsant activity of topiramate and phenytoin in a rat model of ischemia-induced epilepsy.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Brain Ischemia; Epilepsy; Fructose; Male; Phenytoin; Rats; Topiramate | 1996 |
Topiramate for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Fructose; Humans; Phenytoin; Topiramate; Valproic Acid | 1997 |
Anticonvulsant efficacy of topiramate in phenytoin-resistant kindled rats.
Topics: Amygdala; Animals; Anticonvulsants; Disease Models, Animal; Drug Resistance; Electric Stimulation; Epilepsy; Female; Fructose; Kindling, Neurologic; Phenytoin; Prodrugs; Rats; Rats, Wistar; Topiramate | 2000 |
Effects of topiramate on sodium-dependent action-potential firing by mouse spinal cord neurons in cell culture.
Topics: Action Potentials; Animals; Anticonvulsants; Cells, Cultured; Dose-Response Relationship, Drug; Electric Stimulation; Fructose; Lamotrigine; Membrane Potentials; Mice; Neurons; Phenytoin; Sodium Channels; Spinal Cord; Topiramate; Triazines | 2000 |
Effects of topiramate on sustained repetitive firing and spontaneous recurrent seizure discharges in cultured hippocampal neurons.
Topics: Action Potentials; Animals; Anticonvulsants; Calcium Channels; Cells, Cultured; Dose-Response Relationship, Drug; Epilepsy; Fructose; Hippocampus; Models, Neurological; Patch-Clamp Techniques; Phenytoin; Pyramidal Cells; Rats; Sodium Channels; Synaptic Transmission; Topiramate | 2000 |
Preliminary evaluation of oral anticonvulsant treatment in the quinpirole model of bipolar disorder.
Topics: Administration, Oral; Animals; Anticonvulsants; Bipolar Disorder; Brain; Carbamazepine; Disease Models, Animal; Dopamine Agonists; Drug Administration Schedule; Fructose; Hyperkinesis; Motor Activity; Neurons; Phenytoin; Quinpirole; Rats; Receptors, Dopamine; Topiramate; Valproic Acid | 2002 |
Topiramate and phenytoin pharmacokinetics during repetitive monotherapy and combination therapy to epileptic patients.
Topics: Adolescent; Adult; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Male; Middle Aged; Mixed Function Oxygenases; Phenytoin; Topiramate | 2002 |
Topiramate protects against glutamate- and kainate-induced neurotoxicity in primary neuronal-astroglial cultures.
Topics: Animals; Animals, Newborn; Anticonvulsants; Astrocytes; Calcium; Calcium Signaling; Cell Membrane; Cell Survival; Cells, Cultured; Fructose; Glutamic Acid; Immunohistochemistry; Kainic Acid; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Phenytoin; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Topiramate; Valproic Acid | 2003 |
Interaction between anticonvulsants and human placental carnitine transporter.
Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techniques; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Models, Biological; Nipecotic Acids; Organic Cation Transport Proteins; Phenytoin; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Proteins; Solute Carrier Family 22 Member 5; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2004 |
Therapeutic doses of topiramate are not toxic to the developing rat brain.
Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Apoptosis; Brain; Dose-Response Relationship, Drug; Fructose; Neurons; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Topiramate; Valproic Acid | 2004 |
Congenital bilateral perisylvian syndrome with partial epilepsy. Case report with long-term follow-up.
Topics: Adolescent; Cerebral Cortex; Electroencephalography; Epilepsies, Partial; Female; Follow-Up Studies; Fructose; Globus Pallidus; Humans; Intellectual Disability; Magnetic Resonance Imaging; Nervous System Malformations; Phenytoin; Pseudobulbar Palsy; Quadriplegia; Syndrome; Topiramate; Treatment Outcome | 2005 |
[Anticonvulsive pharmacotherapy may aggravate epilepsy course].
Topics: Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Fructose; Humans; Magnetic Resonance Imaging; Phenobarbital; Phenytoin; Topiramate; Valproic Acid | 2005 |
Clinical utility of a continuous intravenous infusion of valproic acid in pediatric patients.
Topics: Administration, Oral; Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Drug Utilization Review; Female; Fructose; Hallucinations; Humans; Hyperammonemia; Infusions, Intravenous; Male; Medical Records; Metabolic Clearance Rate; Migraine Disorders; Phenobarbital; Phenytoin; Retrospective Studies; Seizures; Topiramate; Treatment Outcome; Valproic Acid | 2007 |
Effects of phenytoin and carbamazepine on calcium transport in Caco-2 cells.
Topics: Amines; Anticonvulsants; Biological Transport, Active; Bone Diseases; Caco-2 Cells; Calcium; Carbamazepine; Cell Membrane Permeability; Cyclohexanecarboxylic Acids; Epithelial Cells; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenytoin; Topiramate; Vitamin D | 2007 |
Effects of certain antiepileptics on behavioral and electromyographic seizure patterns induced by maximal electroshock in mice.
Topics: Administration, Oral; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electromyography; Electroshock; Ethosuximide; Fructose; Male; Mice; Phenobarbital; Phenytoin; Seizures; Time Factors; Topiramate | 2007 |
Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Extracellular Fluid; Fructose; Hippocampus; Isoxazoles; Male; Movement; Neurotransmitter Agents; Phenytoin; Rats; Rats, Sprague-Dawley; Topiramate; Zonisamide | 2009 |
Topiramate and phenytoin anti-immobility effect in the mice forced swimming test is reversed by veratrine: Implication for bipolar depression treatment.
Topics: Animals; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Fructose; Locomotion; Male; Membrane Transport Modulators; Mice; Neuropsychological Tests; Phenytoin; Random Allocation; Sodium Channel Agonists; Sodium Channels; Swimming; Time Factors; Topiramate; Veratrine | 2009 |
Valproic acid: long-term effects on children exposed in utero.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Contraindications; Dose-Response Relationship, Drug; Epilepsy; Female; Fructose; Humans; Intelligence; Lamotrigine; Language Development Disorders; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Psychomotor Disorders; Topiramate; Triazines; Valproic Acid | 2009 |
Comparative effectiveness of 10 antiepileptic drugs in older adults with epilepsy.
Topics: Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Resistance; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Treatment Outcome; Triazines | 2010 |
Presence of epileptiform discharges on initial EEGs are associated with failure of retention on first antiepileptic drug in newly diagnosed cryptogenic partial epilepsy: a 2-year observational study.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Carbamazepine; Electroencephalography; Epilepsy, Complex Partial; Female; Fructose; Humans; Kaplan-Meier Estimate; Lamotrigine; Male; Middle Aged; Phenytoin; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2010 |
Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Child; China; Clonazepam; Cyclohexanecarboxylic Acids; Exanthema; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Medicine, Chinese Traditional; Middle Aged; Phenobarbital; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Triazines; Valproic Acid; Young Adult | 2010 |
Status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Child; Clinical Protocols; Fructose; GABA Modulators; Humans; Ketamine; Levetiracetam; Midazolam; Pentobarbital; Phenobarbital; Phenytoin; Piracetam; Propofol; Status Epilepticus; Thiopental; Topiramate; Valproic Acid | 2011 |
Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Calcium; Carbamazepine; Drug Interactions; Epilepsy; Fructose; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Lamotrigine; Male; Nerve Endings; Oxcarbazepine; Phenytoin; Potassium Channel Blockers; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Tetrodotoxin; Topiramate; Triazines; Tritium; Vinca Alkaloids | 2011 |
Development and validation of a reference measurement procedure for certification of phenytoin, phenobarbital, lamotrigine, and topiramate in human serum using isotope-dilution liquid chromatography/tandem mass spectrometry.
Topics: Anticonvulsants; Chromatography, Reverse-Phase; Fructose; Humans; Indicator Dilution Techniques; Lamotrigine; Phenobarbital; Phenytoin; Prohibitins; Reference Standards; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Topiramate; Triazines | 2011 |
[Epilepsy in elderly].
Topics: Aged; Aged, 80 and over; Aging; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Female; Fructose; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Topiramate; Triazines; Valproic Acid | 2011 |
Conversion from enzyme-inducing antiepileptic drugs to topiramate: effects on lipids and C-reactive protein.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; C-Reactive Protein; Carbamazepine; Epilepsy; Female; Fructose; Humans; Lipids; Lipoproteins, LDL; Male; Middle Aged; Phenytoin; Topiramate | 2012 |
Topiramate-induced metabolic acidosis: a case study.
Topics: Acidosis; Acidosis, Renal Tubular; Aged; Anticonvulsants; Cerebral Hemorrhage, Traumatic; Comorbidity; Drug Substitution; Epilepsies, Partial; Fructose; Humans; Male; Phenytoin; Polypharmacy; Schizophrenia, Paranoid; Topiramate | 2012 |
Risk factors for hyperammonemia in pediatric patients with epilepsy.
Topics: Acetazolamide; Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy; Female; Fructose; Humans; Hyperammonemia; Infant; Isoxazoles; Male; Phenobarbital; Phenytoin; Retrospective Studies; Risk Factors; Sex Factors; Topiramate; Valproic Acid; Zonisamide | 2013 |
Levetiracetam add-on therapy in Japanese patients with refractory partial epilepsy.
Topics: Adult; Anticonvulsants; Benzodiazepines; Clobazam; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Complex Partial; Female; Fructose; Humans; Japan; Lamotrigine; Levetiracetam; Male; Middle Aged; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2013 |
Interactions of levetiracetam with carbamazepine, phenytoin, topiramate and vigabatrin in the mouse 6Hz psychomotor seizure model - a type II isobolographic analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Disease Models, Animal; Drug Combinations; Drug Interactions; Fructose; Hand Strength; Levetiracetam; Male; Mice; Phenytoin; Piracetam; Psychomotor Performance; Seizures; Topiramate; Vigabatrin | 2014 |
Antiepileptic drug utilization in Bangladesh: experience from Dhaka Medical College Hospital.
Topics: Adolescent; Adult; Anticonvulsants; Bangladesh; Carbamazepine; Child; Drug Combinations; Epilepsies, Partial; Epilepsy, Generalized; Female; Follow-Up Studies; Fructose; Hospitals, Teaching; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prohibitins; Retrospective Studies; Seizures; Topiramate; Treatment Outcome; Valproic Acid | 2013 |
Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases.
Topics: Amines; Anticonvulsants; Carbamazepine; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Limit of Detection; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tiagabine; Topiramate; Triazines; Valproic Acid | 2014 |
Cross-species pharmacological characterization of the allylglycine seizure model in mice and larval zebrafish.
Topics: Allylglycine; Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Fructose; Levetiracetam; Male; Mice; Phenytoin; Piracetam; Seizures; Topiramate; Treatment Outcome; Valproic Acid; Zebrafish | 2015 |
Differential effects of lacosamide, phenytoin and topiramate on peripheral nerve excitability: An ex vivo electrophysiological study.
Topics: Acetamides; Action Potentials; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; Fructose; In Vitro Techniques; Lacosamide; Male; Phenytoin; Rats; Sciatic Nerve; Topiramate | 2016 |
What is This Rash?
Topics: Adrenal Cortex Hormones; Adult; Anticonvulsants; Drug Hypersensitivity Syndrome; Drug Substitution; Epilepsy; Exanthema; Fructose; Humans; Male; Phenytoin; Remission Induction; Risk Factors; Time Factors; Topiramate; Treatment Outcome | 2016 |
Factors influencing topiramate clearance in adult patients with epilepsy: A population pharmacokinetic analysis.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fructose; Humans; Male; Middle Aged; Models, Biological; Oxcarbazepine; Phenobarbital; Phenytoin; Topiramate; Valproic Acid; Young Adult | 2016 |
Anti-epileptic drugs and bone loss: Phenytoin reduces pro-collagen I and alters the electrophoretic mobility of osteonectin in cultured bone cells.
Topics: Animals; Anticonvulsants; Blotting, Western; Bone and Bones; Carbamazepine; Cell Line; Collagen Type I; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Fructose; Gene Expression Profiling; Lamotrigine; Levetiracetam; Microscopy, Confocal; Osteoblasts; Osteonectin; Phenytoin; Piracetam; Procollagen; Real-Time Polymerase Chain Reaction; Topiramate; Triazines; Valproic Acid | 2016 |
Long-term effect of antiepileptic drug switch on serum lipids and C-reactive protein.
Topics: Anticonvulsants; Biomarkers; C-Reactive Protein; Carbamazepine; Drug Substitution; Drug Therapy, Combination; Epilepsies, Partial; Female; Fructose; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Lipids; Male; Middle Aged; Phenytoin; Piracetam; Time Factors; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2016 |
Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Lamotrigine; Male; Medication Adherence; Middle Aged; Oxcarbazepine; Phenytoin; Proportional Hazards Models; Retrospective Studies; Risk Factors; Taiwan; Topiramate; Triazines; Valproic Acid; Young Adult | 2016 |
Population Pharmacokinetics of Topiramate in Japanese Pediatric and Adult Patients With Epilepsy Using Routinely Monitored Data.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Asian People; Body Weight; Carbamazepine; Child; Child, Preschool; Drug Monitoring; Epilepsy; Female; Fructose; Humans; Male; Middle Aged; Models, Biological; Monitoring, Physiologic; Phenytoin; Seizures; Topiramate; Young Adult | 2017 |
[Drugs news].
Topics: Adolescent; Adult; Age Factors; Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Child; Drug Industry; Duodenal Ulcer; Female; France; Gastroesophageal Reflux; Humans; Male; Migraine Disorders; Pharmacovigilance; Phenytoin; Plasma Substitutes; Polygeline; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors; Stomach Ulcer; Topiramate | 2017 |
Lamotrigine Drug Interactions in Combination Therapy and the Influence of Therapeutic Drug Monitoring on Clinical Outcomes of Adult Patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Clonazepam; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Fructose; Humans; Lamotrigine; Levetiracetam; Male; Phenytoin; Piracetam; Seizures; Topiramate; Triazines; Valproic Acid | 2017 |
A survey of antiepileptic drug responses identifies drugs with potential efficacy for seizure control in Wolf-Hirschhorn syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clobazam; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Quality of Life; Seizures; Topiramate; Wolf-Hirschhorn Syndrome; Young Adult | 2018 |
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Logistic Models; Male; Oxcarbazepine; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Topiramate; Valproic Acid; Young Adult | 2018 |
Antiepileptic Drug Treatment Patterns in Women of Childbearing Age With Epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Anxiety Disorders; Comorbidity; Dissociative Disorders; Epilepsies, Partial; Epilepsy, Generalized; Female; Headache Disorders; Humans; Lamotrigine; Levetiracetam; Mental Disorders; Migraine Disorders; Mood Disorders; Oxcarbazepine; Phenytoin; Retrospective Studies; Risk; Teratogens; Topiramate; Valproic Acid; Young Adult | 2019 |
Estimation of apparent clearance of valproic acid in adult Saudi patients.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Phenytoin; Retrospective Studies; Saudi Arabia; Topiramate; Valproic Acid; Young Adult | 2019 |
Anti-epileptic drug and folic acid usage during pregnancy, seizure and malformation outcomes: Changes over two decades in the Kerala Registry of Epilepsy and Pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Folic Acid; Humans; India; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenytoin; Pregnancy; Pregnancy Complications; Registries; Seizures; Topiramate; Valproic Acid | 2020 |
A Rapid LC-MS-MS Method for the Quantitation of Antiepileptic Drugs in Urine.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Drug Monitoring; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenytoin; Tandem Mass Spectrometry; Topiramate | 2020 |
Incidence rates of severe cutaneous adverse reactions due to antiseizure medication: A nationwide study using health claims data in Korea.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Drug Hypersensitivity Syndrome; Female; Humans; Incidence; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenytoin; Republic of Korea; Severity of Illness Index; Stevens-Johnson Syndrome; Topiramate; Young Adult; Zonisamide | 2021 |
Factors correlated with intracranial interictal epileptiform discharges in refractory epilepsy.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Drug Resistant Epilepsy; Electrocorticography; Female; Humans; Lacosamide; Lamotrigine; Levetiracetam; Male; Mental Recall; Middle Aged; Phenytoin; Time Factors; Topiramate; Zonisamide | 2021 |