phenytoin and thyroxine

phenytoin has been researched along with thyroxine in 126 studies

Research

Studies (126)

Timeframe	Studies, this research(%)	All Research%
pre-1990	100 (79.37)	18.7374
1990's	17 (13.49)	18.2507
2000's	3 (2.38)	29.6817
2010's	6 (4.76)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Selye, H; Taché, J; Taché, Y	1
Fichsel, H; Knöpfle, G	3
Aizawa, T; Kawabe, T; Tsukui, T; Yamada, T	1
Ganes, T; Johannessen, SI; Rootwelt, K	1
Hamada, S; Nishimoto, M	1
Liewendahl, K; Majuri, H	1
Helenius, T; Liewendahl, K; Majuri, H	1
Ramsay, RE; Spellacy, WN; Strauss, RG; Wilder, BJ; Willmore, LJ	1
Cavalieri, RR; Cruse, K; Gavin, LA; Hammond, ME; Wallace, A	1
Kampmann, JP; Lumholtz, BI; Mølholm Hansen, J; Siersbaek-Nielsen, K; Skovsted, L	1
Lamberg, BA; Liewendahl, K; Rosengård, S	1
Bates, D; Evered, DC; Heath, A; Howe, JG; Ratcliffe, WA; Schardt, CW; Yeo, PP	1
Finucane, J	1
Pain, RW; Phillips, PJ	1
Heyma, P; Larkins, RG; Perry-Keene, D; Peter, CT; Ross, D; Sloman, JG	1
Jiang, NS; Tue, KA	1
Hall, RA; Liebling, LI; Nicholson, G	1
Hüfner, M; Knöpfle, M	1
Lenz, PH; Toth, JM; Wien, GH	1
Alsever, RN; Rudolph, MC; Stjernholm, MR	1
Watson, AD	1
Boado, RJ; Cageao, LF; Ceppi, JA; Zaninovich, AA	1
Fujitake, J; Horii, K; Ishikawa, K; Shimbo, S; Tatsuoka, Y	1
Boddaert, A; Chevrier, M; Cordier, A; De Sandro, V; Melcion, C; Richert, L	1
Benson, DM; Goussis, OS; Pappolla, MA; Theodoropoulos, TJ; Zolman, JC	1
Schröder-van der Elst, JP; van der Heide, D	1
Goussis, OS; Theodoropoulos, TJ	1
Mehlman, MA; Schaffer, WT; Tobin, RB; Veech, R	1
Beastall, GH; Brodie, MJ; Larkin, JG; Macphee, GJ	1
Braverman, LE; Moring, AF; Rajatanavin, R; Young, RA	1
Borsey, DQ; Browning, MC; Connacher, AA; Davidson, DL; Jung, RT	1
Weissel, M	1
Biezunski, DR; Shapiro, LE; Surks, MI; Zemel, LR	1
Bai, Y; Barlow, JW; Lim, CF; Stockigt, JR; Topliss, DJ	1
Ceppi, JA; Zaninovich, AA	1
Barańska, H; Frank-Piskorska, A; Konieczna, M	1
György, I; Ilyés, I; Kirilina, S; Tornai, A	1
Bechar, M; Gadoth, N; Kushnir, M; Landau, B; Shavit, G; Weinstein, R	1
Faber, J; Friis, T; Jørgensen, PH; Kirkegaard, C; Lumholtz, IB; Poulsen, S; Siersbaek-Nielsen, K	1
Helenius, T; Liewendahl, K; Majuri, H; Tikanoja, S	1
Coutsoftides, T; Gordon, A	1
Horiguchi, T	1
Davis, PJ; Gregerman, RI; Handwerger, BS	1
Besser, GM; Chan, V; Landon, J	1
Mécs, I; Selye, H; Szabo, S	1
Chan, V	1
Gold, A; Murphy, BE; Pattee, CJ	1
Flock, EV; Mendoza, DM; Owen, CA; Paris, J	1
Brock, RE; Head, WF	1
Crandall, BF; Lippe, BM	1
Oppenheimer, JH	1
Elliott, WJ; Hagen, GA	1
Hansen, JM; Kirkegaard, C; Lauridsen, UB; Siersbaek-Nielsen, K; Skovsted, L	1
Friis, T; Hansen, MJ; Kolendorf, K; Siersbaek-Nielsen, K	1
Pedersen, KO	1
Nicoloff, JT	1
Marx, JV; Richert, DA; Ruegamer, WR; Westerfeld, WW	1
Colton, DG; Mehlman, MA; Ruegamer, WR	1
Madappally, MW; Mehlman, MA; Ruegamer, WR; Tobin, RB	1
Kourounakis, P; Selye, H; Szabo, S	2
Eipe, J	1
Zaninovich, AA	1
Hao, YL; Korcek, L; Tabachnick, M	1
Gharib, H; Mayberry, WE; Ryan, RJ	1
Selye, H	1
Brookeman, VA	1
Davis, PJ; Handwerger, BS	1
Kucera, L; Phillips, G; Sparagana, M	1
Christensen, LK	1
Lipsett, MB	1
Chin, W; Schussler, GC	1
Ito, S	1
Bayley, TA; Higgins, HP; James, W; Row, VV; Vidal, R	1
Johnson, E; Keane, PM; Pegg, PJ	1
Ezrin, C; Volpe, R; Zaninovich, AA	1
Jubiz, W; Meikle, AW; Tyler, FH; West, CD	1
Atkinson, AJ; Goldsmith, RE; Larsen, PR; Wellman, HN	1
Davis, PJ; Gregerman, RI; Spaulding, SW	1
Hao, YL; Tabachnick, M	1
Docter, R; Dolman, A; Hennemann, G	1
Bigler, AH; Jubiz, W; Kumagai, LF; West, CD	1
Kramer, RL; Richens, A	1
Colton, DG; Elfont, EA; Mehlman, MA; Tobin, RB	1
Smith, PJ; Surks, MI	1
Wenzel, KW	1
Braverman, LE; Rajatanavin, R; Young, RA	1
Postellon, DC	1
Kumara-Siri, MH; Mann, DN; Ordene, KW; Surks, MI	1
Oberkotter, LV; Pasquariello, PS; Tenore, A; Zavod, W	1
Gilbert, SS; Shuler, SE; Witherspoon, LR	1
Hiraiwa, M; Miyasaka, M; Mori, K; Shimoda, S; Suzuki, H; Suzuki, Y; Yamazaki, N	1
Breitbart, R; Kaplan, MM	1
Blackshear, JL; Napier, JS; Schultz, AL; Stuart, DD	1
Aanderud, S; Aarbakke, J; Sundsfjord, J	1
Börner, W; Hoffmann, R; Moll, E; Reiners, C	1
Haeckel, R; Haindl, H; Oellerich, M	1
Azizi, F; Braverman, LE; Fang, SL; Ingbar, SH; Theodoropoulos, T; Vagenakis, AG	1
Wilke, TJ	1
Bellamy, G; Green, WL; Nakamura, Y	1
Hayashi, A; Ishii, K; Mizusawa, H; Shoji, S; Tamaoka, A; Usuki, S	1
Liewendahl, K; Ojala, M; Tiihonen, M; Välimäki, M; Waltimo, O	1
Cai, Z; Liu, XM; Ruan, XZ; Zhu, SQ	1
DeFesi, CR; Surks, MI	1
DiStefano, JJ; Kaptein, E; Schröder-van der Elst, JP; van der Bent, C; van der Heide, D; Visser, TJ	2
Kennedy, JA; Lim, CF; Loidl, NM; Stockigt, JR; Topliss, DJ	1
Sarich, TC; Wright, JM	1
Amberson, J; Drinka, PJ	1
Adamczyk, M; Fishpaugh, JR; Mattingly, PG	1
Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA	1
OPPENHEIMER, JH; TAVERNETTI, RR	2
MURPHY, BE; PATTEE, CJ	1
CRISPELL, KR; HARRAH, JD; OLICHNEY, MJ	1
Betteridge, T; Fink, J	1
de Rijke, YB; van Toor, H; Visser, TJ; Visser, WE	1
Fujiwara, R; Hirashima, R; Itoh, T; Kobayashi, Y; Michimae, H; Sasaki, A; Takemoto, H; Tukey, RH	1
Ishii, K; Miyake, Z; Tamaoka, A	1

Reviews

11 review(s) available for phenytoin and thyroxine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Bioavailability and bioinequivalence of drug formulations in small animals. Journal of veterinary pharmacology and therapeutics, 1992, Volume: 15, Issue:2 Topics: Animals; Aspirin; Biological Availability; Cats; Chloramphenicol; Digoxin; Dogs; Fenbendazole; Mitotane; Oxytetracycline; Penicillins; Phenytoin; Theophylline; Therapeutic Equivalency; Thyroxine	1992
[Modification of peripheral thyroid hormone metabolism by drugs]. Acta medica Austriaca, 1988, Volume: 15 Suppl 1 Topics: Amiodarone; Antipyrine; Dexamethasone; Heparin; Humans; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Rifampin; Thiouracil; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1988
Interaction of drugs with thyroid hormone binding sites. Annals of the New York Academy of Sciences, 1973, Nov-26, Volume: 226 Topics: Binding Sites; Blood Proteins; Cell Nucleus; Drug Interactions; Endoplasmic Reticulum; Graves Disease; Humans; Kinetics; Liver; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Thyroid Hormones; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1973
Drugs affecting therapy with anticoagulants. The Medical clinics of North America, 1972, Volume: 56, Issue:1 Topics: Anticoagulants; Chloramphenicol; Clofibrate; Contraceptives, Oral; Coumarins; Diuretics; Drug Interactions; Drug Synergism; Drug-Related Side Effects and Adverse Reactions; Estrogens; Ethanol; Heparin; Humans; Hypnotics and Sedatives; Phenylbutazone; Phenytoin; Salicylates; Thyroxine; Tolbutamide; Vitamin K	1972
Triiodothyronine (T3) radioimmunoassay. A critical evaluation. Mayo Clinic proceedings, 1972, Volume: 47, Issue:12 Topics: Benzoates; Binding Sites; Cross Reactions; Diet; Ethylmercury Compounds; Evaluation Studies as Topic; Geography; Humans; Hyperthyroidism; Hypothyroidism; Immune Sera; Iodine; North America; Phenytoin; Radioimmunoassay; Sulfides; Thyronines; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1972
Factors influencng the rate of metabolism of steroid hormones in man. Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179 Topics: Aldosterone; Androgens; Barbiturates; DDT; Dichlorodiphenyldichloroethane; Estradiol; Estrogens; Hormones; Humans; Hydrocortisone; Metabolism; Microsomes, Liver; Phenobarbital; Phenytoin; Progesterone; Protein Binding; Steroids; Testosterone; Thyroxine	1971
[Recent data on thyroxine-binding protein]. Saishin igaku. Modern medicine, 1967, Volume: 22, Issue:7 Topics: Androgens; Animals; Anticoagulants; Barbiturates; Bilirubin; Carbon Dioxide; Chemical Phenomena; Chemistry, Physical; Diuretics; Estrogens; Glucocorticoids; Humans; Novobiocin; Penicillins; Phenylbutazone; Phenytoin; Salicylates; Thyroid Diseases; Thyroxine; Thyroxine-Binding Proteins; Tolbutamide	1967
Multiple effects of 5,5'-diphenylhydantoin on the thyroid hormone system. Endocrine reviews, 1984,Fall, Volume: 5, Issue:4 Topics: Animals; Enzyme Induction; Humans; Liver; Malate Dehydrogenase; Phenytoin; Pituitary Gland, Anterior; Prospective Studies; Receptors, Cell Surface; Receptors, Thyroid Hormone; Thyroid Hormones; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine	1984
Pharmacological interference with in vitro tests of thyroid function. Metabolism: clinical and experimental, 1981, Volume: 30, Issue:7 Topics: Alpha-Globulins; Diagnostic Errors; Dopamine; Dopamine Antagonists; Estrogens; Female; Glucocorticoids; Histamine Antagonists; Humans; Iodine; Male; Pharmacology; Phenytoin; Protein Binding; Serotonin Antagonists; Somatostatin; Thyroid Diseases; Thyroid Function Tests; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1981
Diagnosis and treatment of congenital hypothyroidism. Comprehensive therapy, 1983, Volume: 9, Issue:2 Topics: Cholestyramine Resin; Congenital Hypothyroidism; Drug Interactions; Female; Humans; Hypothyroidism; Infant, Newborn; Intellectual Disability; Male; Mass Screening; Phenytoin; Thyroid Function Tests; Thyroid Hormones; Thyroxine	1983

Trials

5 trial(s) available for phenytoin and thyroxine

Article	Year
Thyroid hormone levels and protein binding in patients on long-term diphenylhydantoin treatment. Clinical endocrinology, 1977, Volume: 6, Issue:5 Topics: Adult; Aged; Arrhythmias, Cardiac; Depression, Chemical; Female; Humans; Male; Middle Aged; Phenytoin; Protein Binding; Thyrotropin; Thyroxine; Triiodothyronine	1977
Effects of oestrogens on thyroxine turnover in hyperthyroidism. Acta endocrinologica, 1972, Volume: 71, Issue:3 Topics: Adult; Estrogens; Female; Graves Disease; Humans; Hyperthyroidism; Injections, Intravenous; Iodine Isotopes; Male; Methimazole; Middle Aged; Phenols; Phenytoin; Placebos; Thyroid Gland; Thyroxine; Thyroxine-Binding Proteins	1972
Serum thyroxine by competitive protein binding analysis: clinical, statistical and comparative evaluation. The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:2 Topics: Blood Chemical Analysis; Blood Proteins; Chemistry, Clinical; Chromatography, Ion Exchange; Clinical Trials as Topic; Diatrizoate; Humans; Hyperthyroidism; Hypothyroidism; Iopanoic Acid; Methods; Phenytoin; Protein Binding; Salicylates; Thyroxine	1969
[Clinical pharmacology (13): therapy control. Discussion introduction]. Lakartidningen, 1970, Apr-29, Volume: 67, Issue:18 Topics: Clinical Trials as Topic; Drug Therapy; Epilepsy; Humans; Phenytoin; Thyroxine	1970
Thyroid status of patients receiving long-term anticonvulsant therapy assessed by peripheral parameters: a placebo-controlled thyroxine therapy trial. Epilepsia, 1995, Volume: 36, Issue:11 Topics: Adult; Age Distribution; Anticonvulsants; Carbamazepine; Comorbidity; Cross-Over Studies; Double-Blind Method; Epilepsy; Female; Humans; Hypothyroidism; Male; Phenytoin; Placebos; Sex Distribution; Thyroid Function Tests; Thyroid Hormones; Thyroxine	1995

Other Studies

110 other study(ies) available for phenytoin and thyroxine

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Inhibition of the effects of alfathesin and other steroid anesthetics by catatoxic steroids in rats. Arzneimittel-Forschung, 1975, Volume: 25, Issue:10 Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Female; Ketosteroids; Phenobarbital; Phenytoin; Prednisolone; Pregnanediones; Pregnanes; Pregnenes; Pregnenolone Carbonitrile; Rats; Spironolactone; Steroids; Thyroxine; Time Factors	1975
Effects of anticonvulsant drugs on thyroid hormones in epileptic children. Epilepsia, 1978, Volume: 19, Issue:4 Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Cholesterol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Primidone; Protein Binding; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine; Valproic Acid	1978
Studies on the mechanism of goitrogenic action of diphenylthiohydantoin. Endocrinology, 1978, Volume: 102, Issue:6 Topics: Animals; Antithyroid Agents; Iodine; Male; Methimazole; Organ Size; Phenytoin; Propylthiouracil; Rats; Thyroid Gland; Thyroxine; Triiodothyronine	1978
Effect of carbamazepine, phenytoin and phenobarbitone on serum levels of thyroid hormones and thyrotropin in humans. Scandinavian journal of clinical and laboratory investigation, 1978, Volume: 38, Issue:8 Topics: Adult; Carbamazepine; Epilepsy; Humans; Phenobarbital; Phenytoin; Radioimmunoassay; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine; Triiodothyronine, Reverse	1978
Inhibitory effect of certain drugs on thyroid hormone binding by human liver cytosol. Acta endocrinologica, 1979, Volume: 92, Issue:2 Topics: Adult; Aged; Blood Proteins; Cytosol; Dinitrophenols; Female; Heparin; Humans; Liver; Male; Phenytoin; Protein Binding; Salicylates; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1979
Thyroxine, triiodothyronine, and thyrotropin in serum during long-term diphenylhydantoin therapy. Scandinavian journal of clinical and laboratory investigation, 1976, Volume: 36, Issue:2 Topics: Adolescent; Adult; Aged; Feedback; Female; Humans; Long-Term Care; Male; Middle Aged; Phenytoin; Pituitary Gland; Pituitary Hormone-Releasing Hormones; Receptors, Cell Surface; Thyroid Function Tests; Thyrotropin; Thyroxine; Triiodothyronine	1976
Thyroid function tests in patients on long-term treatment with various anticonvulsant drugs. Clinical endocrinology, 1978, Volume: 8, Issue:3 Topics: Adolescent; Adult; Carbamazepine; Female; Humans; Male; Middle Aged; Phenytoin; Primidone; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine; Valproic Acid	1978
[Changes in the thyroid hormone system with combined anticonvulsion treatment of epileptic children and adolescents (author's transl)]. Klinische Padiatrie, 1977, Volume: 189, Issue:2 Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Cholesterol; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Humans; Iodine; Liver; Phenytoin; Primidone; Protein Binding; Thyroid Gland; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins	1977
Epilepsy and pregnancy. Serum thyroxine levels during phenytoin therapy. Obstetrics and gynecology, 1979, Volume: 53, Issue:3 Topics: Abnormalities, Drug-Induced; Administration, Oral; Epilepsy; Female; Fetus; Humans; Infant, Newborn; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Pregnancy Complications; Thyroxine	1979
Serum thyroxine, free T4, triiodothyronine, and reverse-T3 in diphenylhydantoin-treated patients. Metabolism: clinical and experimental, 1979, Volume: 28, Issue:11 Topics: Adult; Humans; Male; Phenytoin; Radioimmunoassay; Radioligand Assay; Thyrotropin; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse	1979
Unaltered metabolism of phenytoin in thyroid disorders. Acta pharmacologica et toxicologica, 1978, Volume: 42, Issue:5 Topics: Adult; Aged; Antipyrine; Female; Half-Life; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Phenytoin; Thyroid Function Tests; Thyroxine	1978
Nuclear binding of triiodothyronine and thyroxine in lymphocytes from subjects with hyperthyroidism, hypothyroidism and resistance to thyroid hormones. Clinica chimica acta; international journal of clinical chemistry, 1978, Feb-01, Volume: 83, Issue:1-2 Topics: Adult; Binding, Competitive; Cell Nucleus; Cells, Cultured; Female; Humans; Hyperthyroidism; Hypothyroidism; Lymphocytes; Male; Phenytoin; Salicylates; Thyroxine; Triiodothyronine	1978
Anticonvulsants and thyroid function. British medical journal, 1978, Jun-17, Volume: 1, Issue:6127 Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine	1978
Anticonvulsants and thyroid function. British medical journal, 1978, Jul-29, Volume: 2, Issue:6133 Topics: Humans; Phenytoin; Thyroxine	1978
Letter: Thyroid-function tests in diphenylhydantoin-treated patients. Clinical chemistry, 1976, Volume: 22, Issue:4 Topics: Erythrocytes; Humans; Phenytoin; Thyroid Function Tests; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1976
Determination of free thyroxine in serum by radioimmunoassay. Clinical chemistry, 1977, Volume: 23, Issue:9 Topics: Cross Reactions; Humans; Hyperthyroidism; Hypothyroidism; Microchemistry; Phenytoin; Radioimmunoassay; Reference Values; Thyroxine	1977
Thyroid dysfunction in female psychiatric patients. The British journal of psychiatry : the journal of mental science, 1976, Volume: 129 Topics: Adult; Age Factors; Aged; Aspirin; Female; Humans; Hypothyroidism; Lithium; Mental Disorders; Middle Aged; Phenytoin; Thyroid Gland; Thyroxine	1976
Pharmacological influences on T4 to T3 conversion in rat liver. Clinica chimica acta; international journal of clinical chemistry, 1976, Nov-01, Volume: 72, Issue:3 Topics: Animals; Dexamethasone; Kinetics; Liver; Phenobarbital; Phenytoin; Rats; Thyroxine; Triiodothyronine	1976
[Influencing of the thyroid hormone system by long-term treatment with 5-5 diphenylhydantion in children and adolescens (author's transl)]. Klinische Padiatrie, 1976, Volume: 188, Issue:5 Topics: Adolescent; Child; Epilepsy; Female; Humans; Hypothalamus; Iodine; Liver; Male; Phenytoin; Protein Binding; Thyroid Gland; Thyroxine; Time Factors	1976
Standardization of incubation time and temperature for eight radioimmunoassays. Clinical chemistry, 1975, Volume: 21, Issue:8 Topics: Aldosterone; Digitoxin; Digoxin; Estradiol; Hormones; Humans; Iodine Radioisotopes; Phenytoin; Radioimmunoassay; Temperature; Testosterone; Thyroxine; Time Factors; Triiodothyronine; Tritium	1975
Thyroid-function tests in diphenylhydantoin-treated patients. Clinical chemistry, 1975, Volume: 21, Issue:10 Topics: Adult; Binding, Competitive; Female; Humans; Male; Phenytoin; Pregnancy; Protein Binding; Seizures; Thyroid Function Tests; Thyrotropin; Thyroxine; Triiodothyronine	1975
Diphenylhydantoin stimulates the intrapituitary conversion of thyroxine to triiodothyronine in the rat. Neuroendocrinology, 1992, Volume: 56, Issue:4 Topics: Animals; Feedback; Male; Phenytoin; Pituitary Gland; Radioimmunoassay; Rats; Rats, Wistar; Thyroxine; Triiodothyronine	1992
[A case of phenytoin intoxication induced by hypothyroidism]. Rinsho shinkeigaku = Clinical neurology, 1991, Volume: 31, Issue:5 Topics: Acute Disease; Adult; Cerebellar Ataxia; Female; Humans; Hypothyroidism; Phenytoin; Thyroid Gland; Thyroxine	1991
Comparison of the effects of propylthiouracil, amiodarone, diphenylhydantoin, phenobarbital, and 3-methylcholanthrene on hepatic and renal T4 metabolism and thyroid gland function in rats. Toxicology and applied pharmacology, 1991, Volume: 111, Issue:2 Topics: Amiodarone; Animals; Body Weight; Cytochrome P-450 Enzyme System; Cytochromes b5; Glucuronosyltransferase; Kidney; Liver; Male; Methylcholanthrene; Microsomes, Liver; Organ Size; Oxygenases; Phenobarbital; Phenytoin; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	1991
Permanent alterations in the hypothalamic-pituitary-thyroid axis in the rat following phenytoin exposure in utero. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1990, Volume: 22, Issue:10 Topics: Animals; Body Weight; Female; Hypothalamo-Hypophyseal System; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	1990
Effects of 5,5'-diphenylhydantoin on thyroxine and 3,5,3'-triiodothyronine concentrations in several tissues of the rat. Endocrinology, 1990, Volume: 126, Issue:1 Topics: Animals; Iodine Radioisotopes; Male; Osmolar Concentration; Phenytoin; Rats; Rats, Inbred Strains; Reference Values; Thyroxine; Tissue Distribution; Triiodothyronine	1990
Dilantin and salicylate effects on hepatic thyroxine bio-availability and dialyzable thyroxine. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1990, Volume: 22, Issue:6 Topics: Adult; Biological Availability; Humans; Liver; Male; Phenytoin; Salicylates; Thyroxine	1990
Inhibition of the effects of thyroid hormone on rat liver by 5,5'-diphenylthiohydantoin. Toxicology and industrial health, 1985, Volume: 1, Issue:1 Topics: Adenine Nucleotides; Animals; Antithyroid Agents; Citric Acid Cycle; Glycolysis; Ketone Bodies; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Phenytoin; Rats; Rats, Inbred Strains; Thyroid Hormones; Thyroxine	1985
Thyroid hormone concentrations in epileptic patients. European journal of clinical pharmacology, 1989, Volume: 36, Issue:3 Topics: Anticonvulsants; Carbamazepine; Drug Combinations; Epilepsy; Humans; Phenytoin; Thyrotropin; Thyroxine; Triiodothyronine; Valproic Acid	1989
Fasting induces the generation of serum thyronine-binding globulin in Zucker rats. Endocrinology, 1985, Volume: 116, Issue:4 Topics: Animals; Body Weight; Fasting; Iodine Radioisotopes; Male; Obesity; Phenytoin; Rats; Rats, Mutant Strains; Rats, Zucker; Receptors, Cell Surface; Receptors, Thyroid Hormone; Sodium Salicylate; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1985
The effective evaluation of thyroid status in patients on phenytoin, carbamazepine or sodium valproate attending an epilepsy clinic. Postgraduate medical journal, 1987, Volume: 63, Issue:744 Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Valproic Acid	1987
5,5'-Diphenylhydantoin decreases the entry of 3,5,3'-triiodo-L-thyronine but not L-thyroxine in cultured GH-producing cells. Acta endocrinologica, 1988, Volume: 117, Issue:3 Topics: Animals; Cell Line; Growth Hormone; Kinetics; Phenytoin; Thyroxine; Triiodothyronine	1988
Drug and fatty acid effects on serum thyroid hormone binding. The Journal of clinical endocrinology and metabolism, 1988, Volume: 67, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Contrast Media; Diuretics; Fatty Acids, Nonesterified; Humans; Oleic Acid; Oleic Acids; Phenytoin; Receptors, Thyroid Hormone; Thyroxine; Triiodothyronine	1988
[Effects of diphenylhydantoin on intrapituitary conversion of T4 to T3 in rats]. Medicina, 1986, Volume: 46, Issue:4 Topics: Animals; Female; Phenytoin; Pituitary Gland; Rats; Rats, Inbred Strains; Thyrotropin; Thyroxine; Triiodothyronine	1986
[Effect of short-term administration of phenytoin on blood serum levels of thyroid hormones]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1987, Feb-23, Volume: 42, Issue:8 Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Humans; Male; Middle Aged; Phenytoin; Thyroxine; Triiodothyronine	1987
Influence of anticonvulsant drugs on thyroid hormones in epileptic children. Acta paediatrica Hungarica, 1985, Volume: 26, Issue:4 Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Humans; Mephenytoin; Phenytoin; Primidone; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1985
Hypothyroidism and phenytoin intoxication. Annals of internal medicine, 1985, Volume: 102, Issue:3 Topics: Aged; Epilepsy; Female; Humans; Hypothyroidism; Phenytoin; Thyrotropin; Thyroxine	1985
The effects of phenytoin (diphenylhydantoin) on the extrathyroidal turnover of thyroxine, 3,5,3'-triiodothyronine, 3,3',5'-triiodothyronine, and 3',5'-diiodothyronine in man. The Journal of clinical endocrinology and metabolism, 1985, Volume: 61, Issue:6 Topics: Aged; Animals; Biotransformation; Diiodothyronines; Female; Humans; Hypothyroidism; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Middle Aged; Phenytoin; Rats; Rats, Inbred Strains; Thyronines; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse	1985
Free thyroxin and free triiodothyronine as measured by equilibrium dialysis and analog radioimmunoassay in serum of patients taking phenytoin and carbamazepine. Clinical chemistry, 1985, Volume: 31, Issue:12 Topics: Adolescent; Adult; Carbamazepine; Dialysis; Female; Humans; Male; Middle Aged; Phenytoin; Radioimmunoassay; Thyrotropin; Thyroxine; Triiodothyronine	1985
Effect of pH on the binding of thyroxine to serum proteins. Acta endocrinologica, 1970, Volume: 65, Issue:3 Topics: Alpha-Globulins; Animals; Dinitrophenols; Female; Humans; Hydrogen-Ion Concentration; Iodine Isotopes; Male; Mice; Phenytoin; Protein Binding; Rats; Serum Albumin; Thyroid Function Tests; Thyroxine; Thyroxine-Binding Proteins	1970
[Clinical study on determination of blood thyroid hormone levels using the protein binding test--free thyroxine index in young children]. Nihon Shonika Gakkai zasshi. Acta paediatrica Japonica, 1971, Volume: 75, Issue:9 Topics: Age Factors; Androgens; Antithyroid Agents; Child; Child, Preschool; Down Syndrome; Dwarfism, Pituitary; Estrogens; Female; Goiter; Humans; Hyperthyroidism; Hypothyroidism; Infant; Iodine; Male; Nephrotic Syndrome; Obesity; Penicillins; Phenobarbital; Phenytoin; Thyroid Function Tests; Thyroiditis; Thyroxine; Umbilical Arteries	1971
Thyroid hormone binding by human serum prealbumin (TBPA). Electrophoretic studies of triiodothyronine-TBPA interaction. The Journal of clinical investigation, 1972, Volume: 51, Issue:3 Topics: Acetamides; Autoradiography; Blood Protein Electrophoresis; Electrophoresis, Disc; Fluorine; Glycolates; Humans; Hydrogen-Ion Concentration; Iodine Isotopes; Male; Phenytoin; Protein Binding; Salicylates; Serum Albumin; Thyroid Function Tests; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1972
Effects of oestrogen on urinary thyrosine excretion. British medical journal, 1972, Dec-23, Volume: 4, Issue:5842 Topics: Adult; Contraceptives, Oral; Estrogens; Ethinyl Estradiol; Female; Humans; Male; Menstruation; Phenytoin; Thyroid Function Tests; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1972
Protection by catatoxic steroids against the paralysis caused by combined treatment with thyroxine and methylphenidate. Neuropharmacology, 1972, Volume: 11, Issue:5 Topics: Androstenols; Animals; Drug Synergism; Estradiol; Ethylestrenol; Female; Humans; Hydroxysteroids; Hyperkinesis; Ketosteroids; Methylphenidate; Norpregnanes; Paralysis; Phenobarbital; Phenytoin; Prednisolone; Pregnenolone Carbonitrile; Progesterone; Propionates; Rats; Rats, Inbred Strains; Spironolactone; Steroids; Thyroxine	1972
The assay of urinary thyroid hormones for assessing thyroid function. Annals of clinical biochemistry, 1974, Volume: 11, Issue:4 Topics: Adult; Circadian Rhythm; Diagnosis, Differential; Estrogens; Female; Humans; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Male; Phenytoin; Pregnancy; Radioimmunoassay; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1974
Clinical evaluation of a new method for the determination of serum thyroxine. The Journal of clinical endocrinology and metabolism, 1966, Volume: 26, Issue:3 Topics: Adult; Blood; Cholesterol; Estrogens; Female; Humans; Hyperthyroidism; Hypoproteinemia; Hypothyroidism; Male; Middle Aged; Phenytoin; Pregnancy; Thyroid Function Tests; Thyroiditis; Thyroxine	1966
Effect of 5,5'-diphenylhydantoin on the metabolism of L-thyroxine-131-I in the rat. Endocrinology, 1966, Volume: 79, Issue:1 Topics: Animals; Bile; Biliary Fistula; In Vitro Techniques; Iodine Isotopes; Liver; Perfusion; Phenytoin; Rats; Thyroid Function Tests; Thyroxine	1966
Mechanisms of antithyroidal activity of methimazole. Journal of pharmaceutical sciences, 1966, Volume: 55, Issue:8 Topics: Animals; Antithyroid Agents; Dogs; Histamine; Hydrogen Peroxide; Iodides; Male; Phenytoin; Protein Binding; Rats; Spectrophotometry; Thyroid Gland; Thyroxine; Tyrosine; Ultraviolet Rays	1966
Turner syndrome with partial deletion of the X chromosome long arm. American journal of diseases of children (1960), 1973, Volume: 126, Issue:2 Topics: Adolescent; Amenorrhea; Dermatoglyphics; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Follicle Stimulating Hormone; Growth Disorders; Humans; Intelligence Tests; Karyotyping; Luteinizing Hormone; Nephrotic Syndrome; Nevus, Pigmented; Phenotype; Phenytoin; Sex Chromatin; Thymidine; Thyroxine; Trimethadione; Tritium; Turner Syndrome	1973
Transport of thyroid hormones in serum and cerebrospinal fluid. The Journal of clinical endocrinology and metabolism, 1973, Volume: 37, Issue:3 Topics: Autoradiography; Chemical Precipitation; Dialysis; Dinitrophenols; Electrophoresis, Polyacrylamide Gel; Humans; Iodine Isotopes; Phenytoin; Sodium Salicylate; Thyroglobulin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1973
The effect of diphenylhydantoin on thyroid function. The Journal of clinical endocrinology and metabolism, 1974, Volume: 39, Issue:4 Topics: Adolescent; Adult; Aged; Female; Humans; Hyperthyroidism; Iodine; Male; Middle Aged; Phenytoin; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine	1974
Evaluation of thyroid status with "effective thyroxine ratio" (E.T.R.). Acta endocrinologica, 1974, Volume: 77, Issue:2 Topics: Adolescent; Adult; Aged; Aspirin; Depression, Chemical; Estrogens; Evaluation Studies as Topic; Female; Humans; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Male; Menopause; Middle Aged; Phenylbutazone; Phenytoin; Pregnancy; Stimulation, Chemical; Sulfadiazine; Sulfathiazoles; Thyroid Function Tests; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1974
A systematic study of variables affecting protein binding of thyroxine and triiodothyronine in serum. Scandinavian journal of clinical and laboratory investigation, 1974, Volume: 34, Issue:3 Topics: Anions; Barbiturates; Buffers; Caffeine; Depression, Chemical; Dialysis; Humans; Hydrogen-Ion Concentration; Iodine Radioisotopes; Methimazole; Osmolar Concentration; Phenytoin; Protein Binding; Salicylates; Temperature; Theophylline; Thyroxine; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine; Ultrafiltration	1974
A new method for the measurement of acute alterations in thyroxine deiodination rate in man. The Journal of clinical investigation, 1970, Volume: 49, Issue:2 Topics: Adrenocorticotropic Hormone; Epinephrine; Humans; Hydrocortisone; Iodine; Iodine Radioisotopes; Methimazole; Methods; Oxytocin; Phenytoin; Potassium Iodide; Prednisolone; Propylthiouracil; Thyrotropin; Thyroxine; Triiodothyronine	1970
Inhibition of the effects of thyroxine by 5,5-diphenyl-2-thiohydantoin. Biochemical pharmacology, 1971, Volume: 20, Issue:11 Topics: Animals; Enzyme Induction; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Heart; Kidney; Leucine; Liver; Male; Mitochondria, Liver; Myocardium; Orotic Acid; Phenytoin; Protein Binding; Rats; Succinate Dehydrogenase; Sulfhydryl Compounds; Thyroxine	1971
Effect of thyroxine and 5,5-diphenyl-2-thiohydantoin on enzyme activities of rat liver and kidney. Endocrinology, 1972, Volume: 90, Issue:6 Topics: Animals; Carboxy-Lyases; Fructose-Bisphosphatase; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glycerolphosphate Dehydrogenase; Isocitrate Dehydrogenase; Kidney; Ligases; Liver; Malate Dehydrogenase; Male; Phenytoin; Phosphogluconate Dehydrogenase; Rats; Stimulation, Chemical; Thyroxine; Time Factors	1972
Mode of action of 5,5'-diphenylthiohydantoin-sites of action of 5,5'-diphenylthiohydantoin in mitochondria in relationship to thyroxine-stimulated responses. Biochemical pharmacology, 1972, Aug-01, Volume: 21, Issue:15 Topics: Animals; Binding Sites; Carbon Isotopes; Carboxy-Lyases; Carnitine; Diet; Dinitrophenols; Drug Interactions; Fructose-Bisphosphatase; Gluconeogenesis; Glucose-6-Phosphatase; Glycerophosphates; In Vitro Techniques; Ligases; Liver; Methimazole; Mitochondria, Liver; Oxygen Consumption; Phenytoin; Pyruvates; Rats; Succinates; Sulfides; Thyroxine	1972
Protection against the neurolathyrism produced by arsanilic acid in the rat. Experimental neurology, 1972, Volume: 35, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Arsenic Poisoning; Biotransformation; Desoxycorticosterone; Female; Hormones; Movement Disorders; Phenobarbital; Phenytoin; Pregnenolone; Rats; Serotonin; Steroids; Thyroxine; Triamcinolone	1972
Effect of oleate, diphenylhydantoin and heparin on the binding of 125 I-thyroxine to purified thyroxine-binding globulin. The Journal of clinical endocrinology and metabolism, 1973, Volume: 36, Issue:2 Topics: Electrophoresis, Starch Gel; Heparin; Humans; In Vitro Techniques; Iodine Isotopes; Oleic Acids; Phenytoin; Protein Binding; Serum Globulins; Thyroxine; Thyroxine-Binding Proteins	1973
Prevention by catatoxic steroids of lithocholic acid-induced biliary concrements in the rat. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 141, Issue:2 Topics: Animals; Bile Acids and Salts; Body Weight; Common Bile Duct; Female; Gallstones; Jaundice; Lithocholic Acid; Liver; Nitriles; Phenobarbital; Phenytoin; Prednisolone; Propionates; Rats; Steroids; Thyroxine; Triamcinolone; Triiodothyronine	1972
Non-Gaussian distribution of serum thyroxine levels for euthyroid population. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1973, Volume: 14, Issue:9 Topics: Adolescent; Adult; Aged; Androgens; Binding, Competitive; Child; Child, Preschool; Estrogens; Female; Humans; Hyperthyroidism; Hypothyroidism; Infant; Infant, Newborn; Male; Middle Aged; Nephrosis; Phenytoin; Pregnancy; Thyroxine	1973
Thyroid hormone binding in dog plasma. Endocrinology, 1973, Volume: 93, Issue:6 Topics: Binding, Competitive; Blood Proteins; Electrophoresis, Polyacrylamide Gel; Halofenate; Hydrogen-Ion Concentration; Iodine Radioisotopes; Phenytoin; Protein Binding; Serum Albumin; Thyroxine; Triiodothyronine	1973
Decreased serum free thyroxine concentration in patients treated with diphenylhydantoin. The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:2 Topics: Adult; Blood Protein Electrophoresis; Humans; Iodine; Iodine Radioisotopes; Middle Aged; Phenytoin; Protein Binding; Thyroxine; Thyroxine-Binding Proteins	1968
The metabolic significance of thyroxine-binding globulin. Studies in a family with decreased thyroxine-binding globulin. Acta endocrinologica, 1969, Volume: 61, Issue:1 Topics: Adolescent; Adult; Aged; Basal Metabolism; Blood Protein Disorders; Child; Epilepsy; Female; Humans; Iodine Radioisotopes; Kinetics; Male; Pedigree; Phenytoin; Sex Chromosomes; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1969
Estimation of thyroxine binding protein capacities using a non-electrophoretic technique. The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:8 Topics: Barbiturates; Blood Protein Electrophoresis; Buffers; Cholestasis; Female; Humans; Multiple Myeloma; Phenytoin; Pregnancy; Protein Binding; Thyroxine; Thyroxine-Binding Proteins	1969
Effects of variations of thyroxine-binding globulin capacity on the disappearance of triiodothyronine from the plasma. The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:12 Topics: Adolescent; Adult; Aged; Anabolic Agents; Binding Sites; Blood Protein Electrophoresis; Blood Proteins; Chromatography, Ion Exchange; Estrogens; Female; Humans; Iodine Radioisotopes; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Phenols; Phenytoin; Protein Binding; Testosterone; Thyroxine; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine	1969
Serum thyroxine specific activity (T4SA) in the diagnosis of thyroid dysfunction. The American journal of medicine, 1969, Volume: 47, Issue:5 Topics: Blood Protein Disorders; Chromatography, Paper; Estrogens; Humans; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Methods; Phenytoin; Salicylates; Serum Albumin; Thyroid Function Tests; Thyroxine; Thyroxine-Binding Proteins	1969
The effect of diphenylhydantoin on thyroxine metabolism in man. The Journal of clinical investigation, 1970, Volume: 49, Issue:6 Topics: Adult; Electrophoresis; Feces; Humans; Iodine Radioisotopes; Kinetics; Male; Middle Aged; Phenytoin; Thyroid Gland; Thyroxine; Thyroxine-Binding Proteins	1970
The three thyroxine-binding proteins in rat serum: binding capacities and effects of binding inhibitors. Endocrinology, 1970, Volume: 87, Issue:5 Topics: Animals; Blood Protein Electrophoresis; Electrophoresis, Disc; Female; Iodine Isotopes; Male; Phenytoin; Rats; Salicylates; Serum Albumin; Thyroxine; Thyroxine-Binding Proteins	1970
Thyroxine-protein interactions. VII. Effect of thyroxine analogs on the binding of 125-I-thyroxine to highly purified human thyroxine-binding globulin. Endocrinology, 1971, Volume: 88, Issue:1 Topics: Acetates; Butyrates; Chromatography, Ion Exchange; Dialysis; Electrophoresis; Humans; Iodine Isotopes; Phenytoin; Propionates; Protein Binding; Starch; Thyroid Hormones; Thyronines; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1971
Relationship between total thyroxine and absolute free thyroxine and the influence of absolute free thyroxine on thyroxine disposal in humans. The Journal of clinical endocrinology and metabolism, 1971, Volume: 33, Issue:1 Topics: Adult; Child; Female; Humans; Immunologic Deficiency Syndromes; Iodine Isotopes; Male; Pedigree; Phenytoin; Sex Chromosomes; Thyroxine; Thyroxine-Binding Proteins	1971
Estimation of thyroxine production rates in non-steady states. The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:6 Topics: Contraceptives, Oral; Female; Humans; Hyperthyroidism; Hypothyroidism; Injections, Intravenous; Iodine Isotopes; Male; Mathematics; Methods; Phenytoin; Salicylates; Sex Factors; Thyroxine; Time Factors	1972
Effect of various steroids and nonsteroidal microsomal enzyme inducers upon propoxyphene intoxication. Neuroendocrinology, 1972, Volume: 9, Issue:5 Topics: Animals; Dextropropoxyphene; Enzyme Induction; Estradiol; Female; Phenobarbital; Phenytoin; Poisoning; Prednisolone; Rats; Thyroxine; Triamcinolone	1972
Two dimensional immunoelectrophoresis of human serum proteins for the investigation of protein drugs. British journal of pharmacology, 1972, Volume: 45, Issue:1 Topics: Aspirin; Blood Proteins; Carbon Isotopes; Humans; Immunoelectrophoresis; Iodine Isotopes; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Thyroxine	1972
Ultrastructural and biochemical alterations of livers from rats treated with 5,5-diphenyl-2-thiohydantoin (DPTH) and thyroxine. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 141, Issue:1 Topics: Acetoacetates; Animals; Caprylates; Carnitine; DNA; Endoplasmic Reticulum; Fatty Acids; Hydroxybutyrates; Lipid Metabolism; Liver; Liver Glycogen; Male; Microscopy, Electron; Mitochondria, Liver; Organ Size; Phenytoin; Proteins; Rats; RNA; Sulfides; Thyroxine	1972
Low protein-high carbohydrate diet induces alterations in the serum thyronine-binding proteins in the rat. Endocrinology, 1982, Volume: 110, Issue:5 Topics: Animals; Body Weight; Dietary Carbohydrates; Male; Phenytoin; Protein-Energy Malnutrition; Rats; Rats, Zucker; Receptors, Cell Surface; Receptors, Thyroid Hormone; Thyroxine; Triiodothyronine	1982
Diphenylhydantoin inhibits the thyrotropin response to thyrotropin-releasing hormone in man and rat. The Journal of clinical endocrinology and metabolism, 1983, Volume: 56, Issue:5 Topics: Aged; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Female; Humans; Male; Phenytoin; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine	1983
A thyroxine-binding protein in human breast milk similar to serum thyroxine-binding globulin. The Journal of clinical endocrinology and metabolism, 1983, Volume: 57, Issue:6 Topics: Albumins; Anilino Naphthalenesulfonates; Blood Proteins; Female; Humans; Lactose; Milk, Human; Phenytoin; Postpartum Period; Pregnancy; Protein Binding; Thyroxine; Thyroxine-Binding Proteins	1983
Estimation of free thyroxin with a new thyroxin analog and a porous-glass solid phase. Clinical chemistry, 1984, Volume: 30, Issue:5 Topics: Female; Glass; Heparin; Humans; Hyperthyroidism; Hypothyroidism; Male; Methods; Phenytoin; Pregnancy; Reagent Kits, Diagnostic; Salicylates; Thyroxine; Thyroxine-Binding Proteins	1984
Lowering effect of diphenylhydantoin on serum free thyroxine and thyroxine binding globulin (TBG). Acta endocrinologica, 1984, Volume: 105, Issue:4 Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Male; Phenytoin; Thyroid Function Tests; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1984
Conversion of thyroxine to triiodothyronine in the anterior pituitary gland and the influence of this process on thyroid status. Hormone and metabolic research. Supplement series, 1984, Volume: 14 Topics: Animals; Cerebral Cortex; Iodide Peroxidase; Iodine Radioisotopes; Iopanoic Acid; Liver; Organ Specificity; Peroxidases; Phenytoin; Pituitary Gland, Anterior; Rats; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	1984
Thyroxine replacement requirements in hypothyroid patients receiving phenytoin. Annals of internal medicine, 1983, Volume: 99, Issue:3 Topics: Adult; Drug Administration Schedule; Female; Humans; Hypothyroidism; Phenytoin; Recurrence; Thyrotropin; Thyroxine; Triiodothyronine	1983
Metabolism of thyroid hormones in isolated rat hepatocytes: studies on the influences of carbamazepine and phenytoin. Acta endocrinologica, 1983, Volume: 104, Issue:4 Topics: Animals; Carbamazepine; Cells, Cultured; Liver; Male; Phenytoin; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine	1983
[Direct and indirect parameters of free thyroxine. I. Method, quality control and in vitro experiments on storage of samples and effect of drugs]. Nuklearmedizin. Nuclear medicine, 1983, Volume: 22, Issue:6 Topics: Aspirin; Blood Preservation; Drug Interactions; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Radioimmunoassay; Thyroxine	1983
Evaluation of EMIT adapted to the (Cobas) Bio centrifugal analyzer. Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1982, Volume: 20, Issue:10 Topics: Centrifugation; Digoxin; Disopyramide; Humans; Immunoenzyme Techniques; Methotrexate; Phenytoin; Radioimmunoassay; Thyroxine	1982
Effect of diphenylhydantoin on hypothalamic-pituitary-thyroid function in the rat. The American journal of physiology, 1980, Volume: 239, Issue:6 Topics: Animals; Hypothalamo-Hypophyseal System; Male; Phenytoin; Rats; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine	1980
Five kits for estimating free thyroxin concentration in serum evaluated, and correlated with other indices to thyroid status. Clinical chemistry, 1982, Volume: 28, Issue:10 Topics: Adolescent; Adult; Aged; Contraceptives, Oral; Female; Humans; Male; Middle Aged; Phenytoin; Pregnancy; Protein Binding; Radioimmunoassay; Reagent Kits, Diagnostic; Thyroid Diseases; Thyroxine; Thyroxine-Binding Proteins	1982
Effects of an inhibitor of hepatic drug metabolism, 2-diethylaminoethyl-2,2-diphenylvalerate HCl (SKF 525-A), on thyroxine metabolism in the rat. Endocrinology, 1981, Volume: 108, Issue:4 Topics: Anaerobiosis; Animals; In Vitro Techniques; Kinetics; Liver; Male; Phenytoin; Proadifen; Rats; Structure-Activity Relationship; Thyroidectomy; Thyrotropin; Thyroxine	1981
Case report: thyrotropin-releasing hormone-induced myoclonus and tremor in a patient with Hashimoto's encephalopathy. The American journal of the medical sciences, 1995, Volume: 310, Issue:5 Topics: Adult; Female; Humans; Menstrual Cycle; Myoclonus; Phenytoin; Prolactin; Thyroid Gland; Thyroiditis, Autoimmune; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Tremor; Valproic Acid	1995
Changes of thyroid hormone levels in epileptic patients. Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1994, Volume: 14, Issue:2 Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Phenytoin; Thyrotropin; Thyroxine; Triiodothyronine; Valproic Acid	1994
Normal serum free thyroid hormone concentrations in patients treated with phenytoin or carbamazepine. A paradox resolved. JAMA, 1996, May-15, Volume: 275, Issue:19 Topics: Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Carrier Proteins; Humans; Phenytoin; Seizures; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	1996
Effects of 5, 5'-diphenylhydantoin on the thyroid status in rats. European journal of endocrinology, 1996, Volume: 134, Issue:2 Topics: Animals; Anticonvulsants; Growth Hormone; Liver; Male; Oxygen Consumption; Phenytoin; Pituitary Gland; Rats; Rats, Wistar; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	1996
Drug effects on triiodothyronine uptake by rat anterior pituitary cells in vitro. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 1996, Volume: 104, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cells, Cultured; Diuretics; Enzyme Inhibitors; Flavonoids; Iodide Peroxidase; Iodine Radioisotopes; Male; Phenytoin; Pituitary Gland, Anterior; Rats; Rats, Wistar; Serum Albumin, Bovine; Thyroxine; Triiodothyronine	1996
Hypothyroxinemia and phenytoin toxicity: a vicious circle. Drug metabolism and drug interactions, 1996, Volume: 13, Issue:2 Topics: Anticonvulsants; Enzyme Induction; Female; Humans; Hypothyroidism; Liver; Middle Aged; Phenytoin; Thyroxine	1996
Effects of 5,5'-diphenylhydantoin on the metabolic pathway of thyroid hormone in rats. European journal of endocrinology, 1997, Volume: 136, Issue:3 Topics: Animals; Feces; Intestinal Mucosa; Kinetics; Male; Phenytoin; Rats; Rats, Wistar; Thyroxine; Triiodothyronine	1997
Medication and low serum thyroxine values in nursing home residents. Southern medical journal, 1998, Volume: 91, Issue:5 Topics: Aged; Aged, 80 and over; Carbamazepine; Euthyroid Sick Syndromes; Female; Frail Elderly; Homes for the Aged; Humans; Male; Nursing Homes; Phenytoin; Prednisone; Salicylates; Serum Albumin; Thyroid Function Tests; Thyrotropin; Thyroxine	1998
Resin-supported labeling reagents. Bioorganic & medicinal chemistry letters, 1999, Jan-18, Volume: 9, Issue:2 Topics: Acridines; Biotin; Chromatography, High Pressure Liquid; Coumarins; Esters; Estriol; Fluorescein; Haptens; Phenytoin; Resins, Plant; Thyroxine	1999
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR. The Journal of endocrinology, 2000, Volume: 167, Issue:3 Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenase Inhibitors; Diazepam; Female; GABA Modulators; Humans; Iodine Radioisotopes; Leucine; Meclofenamic Acid; Mefenamic Acid; Nifedipine; Nitrendipine; Phenylalanine; Phenytoin; Thyroxine; Triiodothyronine; Tryptophan; Tumor Cells, Cultured; Uterine Neoplasms; Verapamil	2000
Displacement of thyroxine from human thyroxine-binding globulin by analogues of hydantoin. Steric aspects of the thyroxinebinding site. The Journal of clinical investigation, 1962, Volume: 41 Topics: Anticonvulsants; Humans; Hydantoins; Imidazoles; Phenytoin; Serum Globulins; Thyroxine; Thyroxine-Binding Globulin	1962
DETERMINATION OF THYROXINE UTILIZING THE PROPERTY OF PROTEIN-BINDING. The Journal of clinical endocrinology and metabolism, 1964, Volume: 24 Topics: Aspirin; Bilirubin; Blood Chemical Analysis; Blood Proteins; Cholesterol; Glucose; Heparin; Hyperthyroidism; Hypothyroidism; Iodides; Iodine; Iodine Isotopes; Mercury; Oxalates; Phenytoin; Potassium; Research; Thyroid Function Tests; Thyroid Hormones; Thyroxine; Triiodothyronine	1964
OBSERVATIONS OF THE EFFECT OF ORGANIC DYES AND DIPHENYLHYDANTOIN ON THE IN VITRO BINDING OF RADIOACTIVE 131-I LABELED L-THYROXINE, L-TRIIODOTHYRONINE AND TETRAIODOTHYROACETIC ACID BY HUMAN ERYTHROCYTES AND SERUM PROTEINS. Acta endocrinologica, 1965, Volume: 48 Topics: Blood Protein Electrophoresis; Blood Proteins; Coloring Agents; Electrophoresis; Erythrocytes; Humans; In Vitro Techniques; Iodine; Iodine Isotopes; Metabolism; Pharmacology; Phenytoin; Thyroxine; Triiodothyronine; Trypan Blue	1965
Studies on the thyroxine-diphenylhydantoin interaction: effect of 5,5'-diphenylhydantoin on the displacement of L-thyroxine from thyroxine-binding globulin (TBG). Endocrinology, 1962, Volume: 71 Topics: Humans; Hydantoins; Phenytoin; Serum Globulins; Thyroid Hormones; Thyroxine; Thyroxine-Binding Globulin	1962
Phenytoin toxicity and thyroid dysfunction. The New Zealand medical journal, 2009, Sep-25, Volume: 122, Issue:1303 Topics: Anticonvulsants; Epilepsy; Female; Follow-Up Studies; Humans; Hypothyroidism; Middle Aged; Phenytoin; Thyroxine	2009
Thyroid status in a large cohort of patients with mental retardation: the TOP-R (Thyroid Origin of Psychomotor Retardation) study. Clinical endocrinology, 2011, Volume: 75, Issue:3 Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Cohort Studies; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Hypothyroidism; Intellectual Disability; Lamotrigine; Linear Models; Male; Middle Aged; Netherlands; Phenobarbital; Phenytoin; Prevalence; Thyroid Gland; Thyrotropin; Thyroxine; Triazines; Triiodothyronine; Valproic Acid	2011
Induction of the UDP-Glucuronosyltransferase 1A1 during the Perinatal Period Can Cause Neurodevelopmental Toxicity. Molecular pharmacology, 2016, Volume: 90, Issue:3 Topics: Animals; Animals, Newborn; Brain; Carbamazepine; Cell Movement; Enzyme Induction; Female; Gene Expression Regulation, Developmental; Genes, Developmental; Glucuronosyltransferase; Humans; Mice, Inbred C57BL; Mice, Transgenic; Milk, Human; Neurodevelopmental Disorders; Phenytoin; Pregnancy; Pregnenolone Carbonitrile; Prenatal Exposure Delayed Effects; RNA, Messenger; Rotarod Performance Test; Thyroxine	2016
Hypothyroidism induced by phenytoin and gabapentin: A Case Report. Medicine, 2018, Volume: 97, Issue:43 Topics: Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypothyroidism; Male; Phenytoin; Thyroxine	2018