phenytoin and tetracycline

phenytoin has been researched along with tetracycline in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199027 (61.36)18.7374
1990's1 (2.27)18.2507
2000's6 (13.64)29.6817
2010's10 (22.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Shepard, TH1
Colburn, WA; Gibaldi, M1
Rane, A; Wilson, JT1
Gross, MA; Yunis, AA1
Moult, PJ; Sherlock, S1
Koide, H1
Harvey, W; Robinson, PB1
Weismann, K1
Albertucci, M; Bailey, RT; Bonavina, L; DeMeester, TR; McChesney, L; Schwizer, W1
Bal, V; Bhide, MB; Rath, S1
Bornuz, F; Hadnagy, C; Macavei, I; Marinca, E; Sass, G1
Burge, SM; Dawber, RP1
Levine, RR; Walsh, CT1
Hahn, I; Krieglstein, G; Krieglstein, J; Tschentscher, K1
Adir, J; Barr, WH1
Johnsgård, M; Pedersen, AO1
Epstein, JH; Sams, WM1
Shklar, G; Sklans, S; Taylor, RG1
Miani, C; Picarelli, A; Sacchi, A1
Harinasula, U; Zimmerman, HJ1
Brown, H1
Beckman, DA; Brent, RL1
Chan, HL1
Zenk, KE1
Melsen, F; Mosekilde, L1
JACOBZINER, H; RAYBIN, HW1
ANDERSON, B; BAILEY, G; ROSENBAUM, JM1
Brandão, MAF; Ferreira, AO; Patrício, FB; Polonini, HC; Raposo, NRB; Silva, SL1

Reviews

4 review(s) available for phenytoin and tetracycline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Evaluation of the clinical inequivalency of drug products of varying bioavailability.
    Annals of clinical research, 1974, Volume: 6, Issue:0

    Topics: Aluminum Hydroxide; Arrhythmias, Cardiac; Biopharmaceutics; Digoxin; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Folic Acid; Half-Life; Humans; Intestinal Absorption; Phenytoin; Research Design; Tetracycline; Therapeutic Equivalency; Time Factors

1974
Mechanisms of teratogenesis.
    Annual review of pharmacology and toxicology, 1984, Volume: 24

    Topics: Aminopterin; Androgens; Animals; Antithyroid Agents; Chromosome Aberrations; Coumarins; Diethylstilbestrol; Embryo, Mammalian; Ethanol; Female; Fetus; Humans; Methotrexate; Methylmercury Compounds; Mutagens; Nucleic Acids; Oxazoles; Phenytoin; Polychlorinated Biphenyls; Pregnancy; Progestins; Teratogens; Tetracycline; Thalidomide; Thyroid Hormones

1984
An overview of perinatal clinical pharmacology.
    Clinics in laboratory medicine, 1981, Volume: 1, Issue:2

    Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digoxin; Female; Fetus; Furosemide; Gentamicins; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Penicillins; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Tetracycline; Theophylline

1981

Other Studies

40 other study(ies) available for phenytoin and tetracycline

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Teratogenicity of therapeutic agents.
    Current problems in pediatrics, 1979, Volume: 10, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Abortion, Induced; Anesthetics; Animals; Anticoagulants; Antineoplastic Agents; Aspirin; Congenital Abnormalities; Drug Evaluation; Drug Evaluation, Preclinical; Female; Hormones; Humans; Male; Methylmercury Compounds; Phenytoin; Pregnancy; Teratogens; Tetracycline; Thalidomide; Tranquilizing Agents; Trimethadione

1979
Pharmacokinetic analysis of drug concentration data obtained during repetitive drug administration.
    Journal of pharmaceutical sciences, 1977, Volume: 66, Issue:4

    Topics: Computers; Humans; Intestinal Absorption; Kinetics; Models, Biological; Pharmaceutical Preparations; Phenytoin; Tetracycline; Time Factors

1977
Clinical pharmacokinetics in infants and children.
    Clinical pharmacokinetics, 1976, Volume: 1, Issue:1

    Topics: Aging; Body Water; Carbamazepine; Child; Child, Preschool; Clindamycin; Dextropropoxyphene; Diazoxide; Dicloxacillin; Digoxin; Ethosuximide; Humans; Infant; Infant, Newborn; Kidney; Kinetics; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Sulfonamides; Tetracycline; Theophylline

1976
Drug-induced inhibition of myeloid colony growth: protective effect of colony-stimulating factor.
    The Journal of laboratory and clinical medicine, 1975, Volume: 86, Issue:3

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Chloramphenicol; Chlorpromazine; Clone Cells; Dose-Response Relationship, Drug; In Vitro Techniques; Leukopenia; Mice; Phenylbutazone; Phenytoin; Tetracycline; Thiamphenicol

1975
Halothane-related hepatitis. A clinical study of twenty-six cases.
    The Quarterly journal of medicine, 1975, Volume: 44, Issue:173

    Topics: Adult; Aged; Anesthesia, General; Bilirubin; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Female; Glucose; Halothane; Humans; Jaundice; Male; Middle Aged; Neomycin; Penicillins; Phenothiazines; Phenytoin; Postoperative Complications; Sulfonamides; Tetracycline; Trimethoprim

1975
[Adverse effect of various drugs on electrolyte metabolism].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1991, Feb-10, Volume: 80, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Deamino Arginine Vasopressin; Diuretics; Humans; Isoniazid; Lithium; Methoxyflurane; Phenytoin; Succinylcholine; Tetracycline; Water-Electrolyte Imbalance

1991
Tooth root resorption induced in rats by diphenylhydantoin and parathyroidectomy.
    British journal of experimental pathology, 1989, Volume: 70, Issue:1

    Topics: Animals; Calcium; Calcium, Dietary; Male; Parathyroid Glands; Parathyroid Hormone; Phenytoin; Phosphates; Rats; Rats, Inbred Strains; Tetracycline; Tooth Resorption; Tooth Root

1989
Chelating drugs and zinc.
    Danish medical bulletin, 1986, Volume: 33, Issue:4

    Topics: Animals; Chelating Agents; Disulfiram; Ethambutol; Humans; Organometallic Compounds; Oxyquinoline; Penicillamine; Phenytoin; Pyridines; Rats; Tetracycline; Zinc

1986
Drug-induced esophageal strictures.
    Annals of surgery, 1987, Volume: 206, Issue:2

    Topics: Adolescent; Adult; Aged; Ascorbic Acid; Aspirin; Esophageal Stenosis; Female; Humans; Male; Manometry; Middle Aged; Phenytoin; Potassium Chloride; Prospective Studies; Quinidine; Radiography; Tetracycline

1987
Mineralisation in experimental fracture repair estimated by tetracycline deposition.
    The Indian journal of medical research, 1986, Volume: 83

    Topics: Animals; Bony Callus; Calcium; Fractures, Bone; Male; Phenytoin; Rats; Tetracycline; Wound Healing

1986
[Bone marrow-damaging effect of various drugs].
    Zeitschrift fur arztliche Fortbildung, 1985, Volume: 79, Issue:9

    Topics: Antitubercular Agents; Bone Marrow; Chloramphenicol; Drug Hypersensitivity; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Hematopoiesis; Humans; Neutropenia; Nitrofurantoin; Pancytopenia; Penicillins; Phenylbutazone; Phenytoin; Red-Cell Aplasia, Pure; Tetracycline; Thrombocytopenia

1985
Stevens-Johnson syndrome and toxic epidermal necrolysis in a patient with systemic lupus erythematosus.
    Journal of the American Academy of Dermatology, 1985, Volume: 13, Issue:4

    Topics: Aged; Female; Humans; Lupus Erythematosus, Systemic; Phenytoin; Stevens-Johnson Syndrome; Tetracycline

1985
Drug absorption in rats pretreated with antibiotics.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 188, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Benzilates; Chlorpromazine; Ileum; Intestinal Absorption; Intestines; Lincomycin; Male; Neomycin; Parasympatholytics; Penicillin V; Phenytoin; Quaternary Ammonium Compounds; Rats; Tetracycline; Time Factors

1974
Distribution of chlorpromazine in a simplified blood influenced by various drugs.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 278, Issue:1

    Topics: Acetazolamide; Animals; Antidepressive Agents; Benzoates; Binding Sites; Binding, Competitive; Cattle; Chlorothiazide; Chlorpromazine; Coumarins; Deoxycholic Acid; Erythrocytes; Fatty Acids; Indomethacin; Phenylbutazone; Phenytoin; Probenecid; Protein Binding; Quinine; Salicylates; Serum Albumin, Bovine; Solubility; Sulfonamides; Suramin; Tetracycline; Thiopental

1973
[The consequence of the preparation factors for the effect of the drug].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Apr-10, Volume: 93, Issue:10

    Topics: Absorption; Administration, Oral; Biopharmaceutics; Capsules; Chemistry, Pharmaceutical; Chloramphenicol; Digoxin; Humans; Nitrofurantoin; Pharmaceutical Preparations; Pharmaceutical Vehicles; Phenytoin; Structure-Activity Relationship; Suppositories; Tablets; Tablets, Enteric-Coated; Tetracycline; Time Factors; Tolbutamide

1973
The experimental production of drug phototoxicity in guinea pigs. I. Using sunlight.
    The Journal of investigative dermatology, 1967, Volume: 48, Issue:1

    Topics: Animals; Chlorothiazide; Chlorpromazine; Demeclocycline; Diphenhydramine; Guinea Pigs; Phenytoin; Photosensitivity Disorders; Plastics; Skin; Sunlight; Tetracycline

1967
Non-equivalent preparations of the same drug.
    Drug and therapeutics bulletin, 1971, Aug-13, Volume: 9, Issue:17

    Topics: Chloramphenicol; Dosage Forms; Humans; Nitrofurantoin; Oxytetracycline; Pharmaceutical Preparations; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Tetracycline; Therapeutic Equivalency; Tolbutamide; Warfarin

1971
Effect of diphenylhydantoin sodium on healing of experimentally produced fractures in rabbit mandibles.
    Journal of oral surgery (American Dental Association : 1965), 1967, Volume: 25, Issue:4

    Topics: Animals; Bone Regeneration; Fracture Fixation; Mandibular Fractures; Microscopy; Phenytoin; Rabbits; Tetracycline; Wound Healing

1967
[Experimental research on the sue of Ca(OH)2 and sodium diphenylhydantoin as biological activators of dentinogenesis].
    Rivista italiana di stomatologia, 1968, Volume: 23, Issue:10

    Topics: Animals; Calcium Hydroxide; Dental Pulp Capping; Dentin; Dentin, Secondary; Dentinogenesis; Dogs; Microscopy, Fluorescence; Phenytoin; Tetracycline

1968
Diphenylhydantoin sodium hepatitis.
    JAMA, 1968, Mar-18, Volume: 203, Issue:12

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Humans; L-Lactate Dehydrogenase; Liver; Male; Meningioma; Middle Aged; Phenytoin; Tetracycline

1968
Tetanus.
    JAMA, 1968, May-13, Volume: 204, Issue:7

    Topics: Adult; Aged; Amobarbital; Child; Chloramphenicol; Humans; Middle Aged; Neostigmine; Oxytetracycline; Phenytoin; Tetanus; Tetanus Antitoxin; Tetanus Toxoid; Tetracycline; Wound Infection; Wounds and Injuries

1968
Observations on drug-induced toxic epidermal necrolysis in Singapore.
    Journal of the American Academy of Dermatology, 1984, Volume: 10, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antipyrine; Barbiturates; Burns; Child; Diagnosis, Differential; Drug Eruptions; Female; Humans; Male; Middle Aged; Necrosis; Penicillamine; Phenytoin; Syndrome; Tetracycline

1984
Trabecular bone mineralization lag time determined by tetracycline double-labeling in normal and certain pathological conditions.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1980, Volume: 88, Issue:2

    Topics: Adult; Aged; Biopsy; Bone and Bones; Bone Diseases; Female; Humans; Hyperparathyroidism; Hyperthyroidism; Hypothyroidism; Ileum; Ilium; Male; Middle Aged; Minerals; Obesity; Osteoblasts; Osteomalacia; Phenytoin; Postoperative Complications; Tetracycline; Time Factors

1980
ISONIAZID INTOXICATIONS.
    New York state journal of medicine, 1964, Mar-01, Volume: 64

    Topics: Amobarbital; Anti-Bacterial Agents; Caffeine; Child; Ions; Isoniazid; New York; Phenylephrine; Phenytoin; Protein Synthesis Inhibitors; Pyridoxine; Sodium; Sodium, Dietary; Tetracycline; Toxicology

1964
TOXIC EPIDERMAL NECROLYSIS.
    JAMA, 1965, Mar-22, Volume: 191

    Topics: Alcoholism; Anti-Bacterial Agents; Chloramphenicol; Chlorpromazine; Drug Eruptions; Drug Therapy; Humans; Hydrocortisone; Mannitol; Methicillin; Paraldehyde; Pathology; Phenytoin; Stevens-Johnson Syndrome; Tetracycline; Thiamine; Toxicology

1965
Feasibility of amlodipine besylate, chloroquine phosphate, dapsone, phenytoin, pyridoxine hydrochloride, sulfadiazine, sulfasalazine, tetracycline hydrochloride, trimethoprim and zonisamide in SyrSpend(®) SF PH4 oral suspensions.
    Journal of pharmaceutical and biomedical analysis, 2016, Jan-25, Volume: 118

    Topics: Administration, Oral; Amlodipine; Chloroquine; Chromatography, High Pressure Liquid; Dapsone; Drug Stability; Drug Storage; Feasibility Studies; Hydrogen-Ion Concentration; Isoxazoles; Phenytoin; Pyridoxine; Sulfadiazine; Sulfasalazine; Suspensions; Tetracycline; Trimethoprim; Zonisamide

2016