phenytoin has been researched along with spironolactone in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (25.00) | 29.6817 |
| 2010's | 7 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Selye, H; Taché, J; Taché, Y | 1 |
| Araki, Y; Miyazaki, T | 1 |
| Mertin, J; Schmiedek, P; Simon, O | 1 |
| Bittar, EE; Tallitsch, RB | 1 |
| Mécs, I; Selye, H; Szabo, S | 1 |
| Kourounakis, P; Selye, H; Szabo, S | 1 |
| Nuss, GW; Risley, EA; Van Arman, CG | 1 |
| Beaulieu, T; Jago, MV; Kovacs, K; Tuchweber, B | 1 |
| Bolch, OH; Warren, JC | 1 |
| Elias, AN; Gwinup, G | 1 |
| Slosberg, PS | 1 |
| Epping, J; Fuchshofen, M; Richter, E | 1 |
| Aron, DC; Findling, JW; Fitzgerald, PA; Forsham, PH; Tyrrell, JB | 1 |
| Lloveres, J; Pérez Fontán, J; Tato, F | 1 |
| Borowicz, KK; Czuczwar, SJ | 1 |
3 review(s) available for phenytoin and spironolactone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Abnormal steroid hormone metabolism during administration of various drugs].
Topics: Alcohol Drinking; Animals; Barbiturates; Estradiol; Humans; Hydrocortisone; Hypertension; Male; Metabolic Clearance Rate; Phenytoin; Prednisone; Rats; Spironolactone; Testosterone | 1979 |
Effects of some clinically encountered drugs on steroid synthesis and degradation.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Drug Interactions; Ethanol; Fetus; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Hydrocortisone; Hydroxycholecalciferols; Liver; Metyrapone; Mitotane; Phenobarbital; Phenytoin; Rifampin; Spironolactone; Steroids | 1980 |
25 other study(ies) available for phenytoin and spironolactone
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Inhibition of the effects of alfathesin and other steroid anesthetics by catatoxic steroids in rats.
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Female; Ketosteroids; Phenobarbital; Phenytoin; Prednisolone; Pregnanediones; Pregnanes; Pregnenes; Pregnenolone Carbonitrile; Rats; Spironolactone; Steroids; Thyroxine; Time Factors | 1975 |
The influence of aldosterone and anticonvulsant drugs on electroencephalographic and clinical disturbances induced by the spirolactone derivative, potassium canrenoate.
Topics: Aldosterone; Animals; Anticonvulsants; Brain; Diazepam; Disease Models, Animal; Dogs; Electroencephalography; Epilepsy; Female; Male; Phenytoin; Spironolactone | 1975 |
Mode of stimulation by aldosterone of the sodium efflux in barnacle muscle fibres: effects of ouabain, ethacrynic acid, diphenylhydantoin, (ATPMg)(2-), adenine translocase inhibitors, pyruvate and oxythiamine.
Topics: Adenosine Triphosphate; Aldosterone; Animals; Atractyloside; Biological Transport, Active; Bongkrekic Acid; Dactinomycin; Ethacrynic Acid; In Vitro Techniques; Muscles; Ouabain; Oxythiamine; Phenytoin; Phosphatidylserines; Pyruvates; Sodium; Spironolactone; Stimulation, Chemical | 1976 |
Protection by catatoxic steroids against the paralysis caused by combined treatment with thyroxine and methylphenidate.
Topics: Androstenols; Animals; Drug Synergism; Estradiol; Ethylestrenol; Female; Humans; Hydroxysteroids; Hyperkinesis; Ketosteroids; Methylphenidate; Norpregnanes; Paralysis; Phenobarbital; Phenytoin; Prednisolone; Pregnenolone Carbonitrile; Progesterone; Propionates; Rats; Rats, Inbred Strains; Spironolactone; Steroids; Thyroxine | 1972 |
Protection by catatoxic steroids, phenobarbital and diphenylhydantoin against methaqualone intoxication.
Topics: Androstenes; Animals; Enzyme Induction; Ethylestrenol; Female; Hydroxysteroids; Ketosteroids; Methaqualone; Movement Disorders; Nitriles; Norsteroids; Oxandrolone; Phenobarbital; Phenytoin; Pregnenolone; Propionates; Rats; Spironolactone; Steroids | 1972 |
Interactions of aspirin, indomethacin and other drugs in adjuvant-induced arthritis in the rat.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Body Weight; Chlorpromazine; Cyclophosphamide; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Hydrocortisone; Indomethacin; Male; Mycobacterium; Phenytoin; Prednisolone; Rats; Salicylates; Spironolactone; Time Factors | 1973 |
Effect of steroidal and nonsteroidal microsomal enzyme inducers on the hepatotoxicity of pyrrolizidine alkaloids in rats.
Topics: Animals; Enzyme Induction; Ethylestrenol; Female; Hepatectomy; Kidney; Liver; Lung; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Pregnenolone Carbonitrile; Prodigiosin; Pyrroles; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Spironolactone | 1974 |
Induction of premature menstruation with catatoxic steroids.
Topics: Abortion, Therapeutic; Adult; Biotransformation; Body Temperature; Contraceptives, Oral; Endometrium; Female; Humans; Menstruation; Nandrolone; Ovulation; Oxymetholone; Phenytoin; Pregnancy; Progesterone; Rape; Spironolactone; Steroids; Stimulation, Chemical; Time Factors | 1971 |
Symptomatic unruptured giant aneurysms: medical treatment.
Topics: Aged; Antihypertensive Agents; Female; Humans; Hydrochlorothiazide; Intracranial Aneurysm; Middle Aged; Phenytoin; Radiography; Spironolactone | 1982 |
[Enterohepatic circulation in liver diseases].
Topics: Animals; Barbiturates; Bile Acids and Salts; Biotransformation; Bisacodyl; Chloramphenicol; Cholestasis; Digitoxin; Enterohepatic Circulation; Humans; Liver Cirrhosis; Liver Diseases; Neomycin; Phenytoin; Rats; Spironolactone | 1980 |
Cushing's syndrome: problems in diagnosis.
Topics: ACTH Syndrome, Ectopic; Adenoma; Adrenal Cortex Function Tests; Adrenocortical Hyperfunction; Adult; Alcoholism; Bipolar Disorder; Cushing Syndrome; Dexamethasone; Diagnosis, Differential; Estrogens; Female; Humans; Hydrocortisone; Male; Middle Aged; Obesity; Phenytoin; Pituitary Neoplasms; Spironolactone | 1981 |
[The effects of diphenylhydantoin and spironolactone on the digoxin pharmacokinetics in the rabbit (author's transl)].
Topics: Animals; Digoxin; Kinetics; Phenytoin; Rabbits; Radioimmunoassay; Spironolactone; Time Factors | 1980 |
Influence of aminoglutethimide and spironolactone on the efficacy of carbamazepine and diphenylhydantoin against amygdala-kindled seizures in rats.
Topics: Aminoglutethimide; Amygdala; Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Therapy, Combination; Female; Hydrocortisone; Kindling, Neurologic; Male; Motor Activity; Phenytoin; Rats; Rats, Wistar; Rotarod Performance Test; Seizures; Spironolactone | 2005 |