phenytoin has been researched along with riluzole in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 10 (50.00) | 29.6817 |
| 2010's | 8 (40.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Anger, T; Madge, DJ; Mulla, M; Riddall, D | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bernardi, G; Spadoni, F; Stefani, A | 1 |
| Borowicz, KK; Czuczwar, SJ; Drelewska, E; Rwiader, M | 1 |
| Donnelly, DF; Faustino, EV | 1 |
| Golomb, D; Yaari, Y; Yue, C | 1 |
| Castro-Alamancos, MA; Rigas, P; Tawara-Hirata, Y | 1 |
| Ates, O; Cakir, CO; Cayli, SR; Gurses, I; Kocak, A; Tarim, O; Turkoz, Y | 1 |
| Diao, L; Hellier, JL; Staley, KJ; Uskert-Newsom, J; Williams, PA; Yee, AS | 1 |
| Clement, EM; Garcia-Rill, E; Greenfield, LJ; Kang, YJ; Lee, SH; Park, IH; Santaniello, S; Smith, BN; Sumsky, SL; Xiang, Y | 1 |
2 review(s) available for phenytoin and riluzole
| Article | Year |
|---|---|
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Sodium Channel Blockers; Sodium Channels; Stroke | 2001 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
18 other study(ies) available for phenytoin and riluzole
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Species independence in brain tissue binding using brain homogenates.
Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity | 2011 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Differential inhibition by riluzole, lamotrigine, and phenytoin of sodium and calcium currents in cortical neurons: implications for neuroprotective strategies.
Topics: Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Cerebral Cortex; Electric Conductivity; Excitatory Amino Acid Antagonists; Lamotrigine; Male; Neurons; Neuroprotective Agents; Phenytoin; Rats; Rats, Wistar; Riluzole; Sodium; Thiazoles; Triazines | 1997 |
Interactions between riluzole and conventional antiepileptic drugs -- a comparison of results obtained in the subthreshold method and isobolographic analysis.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Riluzole; Seizures; Valproic Acid | 2004 |
An important functional role of persistent Na+ current in carotid body hypoxia transduction.
Topics: Action Potentials; Animals; Carotid Body; Catecholamines; Chemoreceptor Cells; Dose-Response Relationship, Drug; Female; Hypoxia; In Vitro Techniques; Male; Nodose Ganglion; Patch-Clamp Techniques; Phenytoin; Plethysmography, Whole Body; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Riluzole; Signal Transduction; Sodium Channel Blockers; Sodium Channels | 2006 |
Contribution of persistent Na+ current and M-type K+ current to somatic bursting in CA1 pyramidal cells: combined experimental and modeling study.
Topics: Action Potentials; Animals; Anthracenes; Calcium; Electrophysiology; Indoles; Male; Models, Neurological; Models, Theoretical; Neurons; Phenytoin; Potassium Channel Blockers; Potassium Channels; Pyramidal Cells; Pyridines; Rats; Rats, Inbred Strains; Riluzole; Sodium Channel Blockers; Sodium Channels | 2006 |
Resonance (approximately 10 Hz) of excitatory networks in motor cortex: effects of voltage-dependent ion channel blockers.
Topics: Anesthetics, Local; Animals; Calcium Channel Blockers; Electrophysiology; Ethosuximide; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ion Channels; Magnesium; Mibefradil; Mice; Motor Cortex; Neocortex; Phenytoin; Potassium Channel Blockers; Potassium Channels; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Riluzole; Sodium Channel Blockers; Tetrodotoxin | 2007 |
Comparative neuroprotective effect of sodium channel blockers after experimental spinal cord injury.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Lipid Peroxidation; Locomotion; Male; Mexiletine; Motor Activity; Phenytoin; Psychomotor Performance; Rats; Rats, Wistar; Riluzole; Sodium Channel Blockers; Spinal Cord Injuries; Statistics, Nonparametric; Time Factors; Water | 2007 |
Diphenytoin, riluzole and lidocaine: three sodium channel blockers, with different mechanisms of action, decrease hippocampal epileptiform activity.
Topics: Action Potentials; Animals; CA3 Region, Hippocampal; Electric Stimulation; Evoked Potentials; Lidocaine; Male; Phenytoin; Rats; Riluzole; Voltage-Gated Sodium Channel Blockers | 2013 |
The critical role of persistent sodium current in hippocampal gamma oscillations.
Topics: Animals; CA1 Region, Hippocampal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABAergic Neurons; Gamma Rhythm; Hippocampus; Inhibitory Postsynaptic Potentials; Interneurons; Mice; Optogenetics; Parvalbumins; Patch-Clamp Techniques; Phenytoin; Pyramidal Cells; Riluzole; Sodium; Voltage-Gated Sodium Channel Blockers | 2020 |