phenytoin has been researched along with quinine in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (53.66) | 18.7374 |
| 1990's | 3 (7.32) | 18.2507 |
| 2000's | 9 (21.95) | 29.6817 |
| 2010's | 7 (17.07) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Andersson, K; Borg, P; Frostell-Karlsson, A; Hämäläinen, M; Karlsson, R; Remaeus, A; Roos, H | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Caron, G; Ermondi, G | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Aster, RH; Cimo, PL; Desai, RG; Pino, JL; Pisciotta, AV | 1 |
| Anderson, DC; Davis, RJ; Dove, JT; Griggs, RC | 1 |
| Amabeoku, GJ; Chikuni, O | 1 |
| Røed, A | 1 |
| Herchuelz, A; Lebrun, P; Plasman, PO | 1 |
| Larsen, LS; Marcus, SM; Sterrett, JR; Whitehead, B | 1 |
| Cadden, JJ; Feigelson, EB | 1 |
| Hahn, I; Krieglstein, G; Krieglstein, J; Tschentscher, K | 1 |
| Uono, M | 1 |
| Falk, M; Fürst, W | 1 |
| McBay, AJ | 1 |
| Esteban, A; Giménez-Roldán, S | 1 |
| Bastos, ML; Jukofsky, D; Mulé, SJ | 1 |
| Megahed, MS; Smith, BH; Weintraub, MI | 1 |
| Jacobsen, CD | 1 |
| Balwani, JH; Kulkarni, SD; Phansalkar, AG | 1 |
| Mulé, SJ | 1 |
| Satoyoshi, E | 1 |
| Beyer, KH; Frisius, H | 1 |
| Guillory, JK; Hwang, SC; Lach, JL | 1 |
| Desbordes, JM; Hamard, H | 1 |
| Brooke, OG; Evans, AN; West, RJ | 1 |
| Akino, C; Amabeoku, GJ; Chikuni, O; Mutetwa, S | 1 |
| ALEXANDER, B; PECHET, L; WEINTRAUB, RM | 1 |
| Criddle, J; Fabre, C; Klein, JL; Nolder, D | 1 |
| Brown, HS; Chadwick, A; Houston, JB | 1 |
| Laurin, LP; Lévesque, R; Roy, L | 1 |
4 review(s) available for phenytoin and quinine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Treatment of myotonic dystrophy].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Chlordiazepoxide; Chlormezanone; Diazepam; Female; Humans; Ion Exchange Resins; Male; Mephenesin; Methocarbamol; Myotonia; Phenytoin; Procainamide; Quinine; Thyroid Hormones; Zoxazolamine | 1970 |
Toxicological findings in fatal poisonings.
Topics: 1-Propanol; Alcoholic Intoxication; Amphetamine; Carbon Monoxide Poisoning; Chloral Hydrate; Chlordiazepoxide; Dextropropoxyphene; Diazepam; Ethchlorvynol; Glutethimide; Heroin; Humans; Meprobamate; Methadone; Methanol; Morphine; Orphenadrine; Paraldehyde; Pentazocine; Phenothiazines; Phenytoin; Poisoning; Quinine; Salicylates; Toxicology; Tranquilizing Agents | 1973 |
[Iatrogenic pathology of the optic nerve].
Topics: Adrenal Cortex Hormones; Antiprotozoal Agents; Chloramphenicol; Contraceptives, Oral; Ethambutol; Female; Humans; Iatrogenic Disease; Isoniazid; Monoamine Oxidase Inhibitors; Optic Nerve Diseases; Phenytoin; Quinine; Radiotherapy; Surgical Procedures, Operative; Vitamins | 1982 |
1 trial(s) available for phenytoin and quinine
| Article | Year |
|---|---|
Pharmacokinetic interaction of single doses of quinine and carbamazepine, phenobarbitone and phenytoin in healthy volunteers.
Topics: Administration, Oral; Adult; Carbamazepine; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Quinine | 1993 |
36 other study(ies) available for phenytoin and quinine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Biosensor analysis of the interaction between immobilized human serum albumin and drug compounds for prediction of human serum albumin binding levels.
Topics: Binding Sites; Biosensing Techniques; Digitoxin; Drug Stability; Humans; Molecular Weight; Naproxen; Orosomucoid; Pharmaceutical Preparations; Protein Binding; Quinine; Rifampin; Ritonavir; Serum Albumin; Solvents; Warfarin | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Detection of drug-dependent antibodies by the 51Cr platelet lysis test: documentation of immune thrombocytopenia induced by diphenylhydantoin, diazepam, and sulfisoxazole.
Topics: Adolescent; Antibodies; Antibody Specificity; Blood Platelets; Chromium Radioisotopes; Diazepam; Female; Humans; Male; Middle Aged; Phenytoin; Quinidine; Quinine; Sulfisoxazole; Thrombocytopenia | 1977 |
Cardiac conduction in myotonic dystrophy.
Topics: Adolescent; Adult; Electrocardiography; Heart; Humans; Middle Aged; Myotonic Dystrophy; Phenytoin; Procainamide; Quinine; Time Factors | 1975 |
Effects of some GABAergic agents on quinine-induced seizures in mice.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Diazepam; Male; Mice; Mice, Inbred Strains; Muscimol; Phenobarbital; Phenytoin; Quinine; Receptors, GABA-A; Seizures | 1992 |
Selective potentiation of subtetanic and tetanic contractions by the calcium-channel antagonist nifedipine in the rat diaphragm preparation.
Topics: Animals; Caffeine; Calcium; Diaphragm; Electric Stimulation; Female; In Vitro Techniques; Male; Membranes; Muscle Contraction; Nifedipine; Phenytoin; Potassium; Quinine; Rats; Rats, Inbred Strains; Respiratory Muscles | 1991 |
Effect of extracellular sodium removal upon 86Rb outflow from pancreatic islet cells.
Topics: Ammonium Chloride; Animals; Calcium; Extracellular Space; Glucose; Islets of Langerhans; Kinetics; Ouabain; Phenytoin; Quinine; Rats; Rubidium Radioisotopes; Sodium; Tetraethylammonium; Tetraethylammonium Compounds | 1989 |
Adjunctive therapy of phenytoin overdose--a case report using plasmaphoresis.
Topics: Adult; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Microsomes, Liver; Mushroom Poisoning; Paraquat; Parathion; Phenytoin; Plasmapheresis; Quinine; Suicide, Attempted | 1986 |
Changing patterns of drug abuse in New York City.
Topics: Adolescent; Adult; Amitriptyline; Amphetamines; Antipsychotic Agents; Barbiturates; Codeine; Dextropropoxyphene; Female; Glutethimide; Heroin Dependence; Humans; Male; Methadone; Morphine; New York City; Phenothiazines; Phenytoin; Quinine; Substance-Related Disorders | 1974 |
Distribution of chlorpromazine in a simplified blood influenced by various drugs.
Topics: Acetazolamide; Animals; Antidepressive Agents; Benzoates; Binding Sites; Binding, Competitive; Cattle; Chlorothiazide; Chlorpromazine; Coumarins; Deoxycholic Acid; Erythrocytes; Fatty Acids; Indomethacin; Phenylbutazone; Phenytoin; Probenecid; Protein Binding; Quinine; Salicylates; Serum Albumin, Bovine; Solubility; Sulfonamides; Suramin; Tetracycline; Thiopental | 1973 |
[Drug permeation through synthetic lipid membranes. Permeability of lecithin-collodium membranes for drugs and metabolites].
Topics: Buffers; Caffeine; Diffusion; Hexobarbital; Hydrogen-Ion Concentration; Kinetics; Membranes, Artificial; Models, Chemical; Papaverine; Phenobarbital; Phenytoin; Phosphatidylcholines; Quinine; Salicylates; Solutions; Time Factors | 1974 |
Orbicularis oculi "myotonia" in hypothyroid myopathy.
Topics: Cold Temperature; Diazepam; Electromyography; Humans; Hypothyroidism; Male; Middle Aged; Muscle Contraction; Neuromuscular Diseases; Oculomotor Muscles; Phenytoin; Quinine; Triiodothyronine | 1973 |
Routine identification of drugs of abuse in human urine. 3. Differential elution of the XAD-2 resin.
Topics: Amitriptyline; Amphetamine; Barbiturates; Chromatography, Thin Layer; Dextropropoxyphene; Humans; Hydrogen-Ion Concentration; Methods; Pharmaceutical Preparations; Phenobarbital; Phenylpropanolamine; Phenytoin; Quinine; Resins, Plant; Solvents; Substance-Related Disorders | 1973 |
Myotonic-like syndrome in multiple sclerosis.
Topics: Adult; Female; Humans; Male; Multiple Sclerosis; Muscle Cramp; Myotonia; Phenytoin; Quinine; Spasm | 1970 |
[Drug-induced anemias].
Topics: Adrenal Cortex Hormones; Anemia; Barbiturates; Bone Marrow; Chloramphenicol; Chlorpromazine; Dihydroxyphenylalanine; Gastrointestinal Hemorrhage; Gold; Humans; Hypoglycemic Agents; Indomethacin; Isoniazid; Nitrofurantoin; Phenacetin; Phenylbutazone; Phenytoin; Quinidine; Quinine; Salicylates; Sulfonamides | 1970 |
Influence of some antiarrhythmic agents on electrically induced convulsive seizures in rats.
Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Chloroquine; Electroshock; Female; Lidocaine; Male; Phenytoin; Procainamide; Procaine; Quinidine; Quinine; Rats; Seizures; Time Factors; Water | 1970 |
Routine identification of drugs of abuse in human urine. I. Application of fluorometry, thin-layer and gas-liquid chromatography.
Topics: Amphetamine; Analgesics; Barbiturates; Chromatography, Gas; Chromatography, Thin Layer; Fluorometry; Glutethimide; Humans; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Indicators and Reagents; Morphinans; Morphine; Phenothiazines; Phenytoin; Psychopharmacology; Quinine; Substance-Related Disorders; Tranquilizing Agents | 1971 |
Recurrent muscle spasms of central origin.
Topics: Bone Diseases, Developmental; Brain Diseases; Carbohydrate Metabolism, Inborn Errors; Child; Diarrhea; Electromyography; Endocrine System Diseases; Female; Gluconates; Humans; Male; Muscle Cramp; Phenytoin; Procainamide; Quinine | 1967 |
[A severe quinine poisoning: clinic, toxicology and therapy].
Topics: Adult; Diuresis; Electrocardiography; Eye Manifestations; Female; Forensic Medicine; Gastric Juice; Heart Arrest; Humans; Muscles; Phenytoin; Poisoning; Pupil; Quinine; Spectrophotometry; Suicide; Tolazoline; Tromethamine | 1969 |
Interactions between pharmaceutical compounds by thermal methods.
Topics: Acetaminophen; Aspirin; Atropine; Bile Acids and Salts; Caffeine; Drug Compounding; Drug Incompatibility; Drug Stability; Methods; Phenacetin; Phenobarbital; Phenytoin; Quinine; Temperature; Theophylline; Thermodynamics; Time Factors; Vitamin K | 1969 |
The ingestion by pregnant women of substances toxic to the foetus.
Topics: Abnormalities, Drug-Induced; Barbiturates; Clitoris; Diazepam; Disorders of Sex Development; Doxylamine; Female; Fetal Alcohol Spectrum Disorders; Humans; Hydroxyprogesterones; Infant, Newborn; Infant, Newborn, Diseases; Male; Phenytoin; Pregnancy; Progesterone Congeners; Quinine; Substance Withdrawal Syndrome | 1980 |
Rapid diagnosis of drug-induced thrombocytopenic purpura. Report of three cases due to quinine, quinidine, and Dilantin.
Topics: Humans; Hydantoins; Phenytoin; Purpura; Purpura, Thrombocytopenic; Quinidine; Quinine; Thrombocytopenia | 1962 |
Recrudescence of imported falciparum malaria after quinine therapy: potential drug interaction with phenytoin.
Topics: Anticonvulsants; Antimalarials; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Cerebral; Malaria, Falciparum; Phenytoin; Quinine; Recurrence | 2005 |
Use of isolated hepatocyte preparations for cytochrome P450 inhibition studies: comparison with microsomes for Ki determination.
Topics: Animals; Catalysis; Cells, Cultured; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Enzyme Inhibitors; Fluconazole; Fluoxetine; Fluvoxamine; Hepatocytes; Ketoconazole; Kinetics; Male; Miconazole; Microsomes, Liver; Midazolam; Phenytoin; Quinine; Rats; Rats, Sprague-Dawley; Tolbutamide | 2007 |
Hemodiafiltration does not improve drug protein binding compared to conventional hemodialysis: an in vitro study.
Topics: Anticonvulsants; Antimalarials; Hemodiafiltration; Humans; Kidney Failure, Chronic; Phenytoin; Protein Binding; Quinine; Renal Dialysis | 2012 |