phenytoin has been researched along with progabide in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, JK; Wall, GM | 1 |
| Bartholini, G; Desarmenien, M; Feltz, P; Headley, PM; Kaplan, JP; Lloyd, KG; Raizon, BM; Worms, P | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Lloyd, KG | 1 |
| Graves, NM; Holmes, GB; Leppik, IE | 1 |
| Chadwick, D; Crawford, P | 1 |
| Bowman, T; Cloyd, J; Crosby, C; Dreifuss, FE; Graves, N; Jacobs, M; Leppik, IE; Porter, R; Santilli, N; Stackman, J | 1 |
| Brundage, RC; Cloyd, JC; Graves, NM; Leppik, IE; Welty, TE | 1 |
| Schmidt, D; Utech, K | 1 |
| Chweh, AY; Swinyard, EA; Wolf, HH | 1 |
| Burke, JT; Thénot, JP | 1 |
| Fariello, RG; Golden, GT | 1 |
2 review(s) available for phenytoin and progabide
| Article | Year |
|---|---|
[GABAergic theory of epilepsy].
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Benzodiazepines; Bicuculline; Brain; Dogs; Epilepsy; gamma-Aminobutyric Acid; Humans; Mice; Nerve Endings; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Receptors, GABA-A; Synapses; Valproic Acid | 1986 |
Determination of antiepileptic drugs.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Chromatography, Liquid; Clonazepam; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Mephenytoin; Monitoring, Physiologic; Phenytoin; Primidone; Succinimides; Valproic Acid | 1985 |
5 trial(s) available for phenytoin and progabide
| Article | Year |
|---|---|
Compliant populations: variability in serum concentrations.
Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Felbamate; Female; gamma-Aminobutyric Acid; Humans; Male; Patient Compliance; Phenylcarbamates; Phenytoin; Propylene Glycols; Random Allocation | 1988 |
A comparative study of progabide, valproate, and placebo as add-on therapy in patients with refractory epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Patient Compliance; Phenytoin; Valproic Acid | 1986 |
A controlled study of progabide in partial seizures: methodology and results.
Topics: Adolescent; Adult; Carbamazepine; Clinical Trials as Topic; Female; gamma-Aminobutyric Acid; Humans; Male; Phenytoin; Seizures | 1987 |
Effect of progabide on serum phenytoin and carbamazepine concentrations.
Topics: Adult; Carbamazepine; Convulsants; Double-Blind Method; Drug Evaluation; Female; gamma-Aminobutyric Acid; Humans; Male; Phenytoin; Random Allocation; Seizures | 1987 |
Progabide for refractory partial epilepsy: a controlled add-on trial.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Random Allocation | 1986 |
6 other study(ies) available for phenytoin and progabide
| Article | Year |
|---|---|
Metabolism of 3-(p-chlorophenyl)pyrrolidine. Structural effects in conversion of a prototype gamma-aminobutyric acid prodrug to lactam and gamma-aminobutyric acid type metabolites.
Topics: Amino Acids; Animals; Baclofen; Brain; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; gamma-Aminobutyric Acid; Isoniazid; Lactams; Liver; Male; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Molecular Structure; Monoamine Oxidase; Oxidation-Reduction; Prodrugs; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1989 |
New anticonvulsants: Schiff bases of gamma-aminobutyric acid and gamma-aminobutyramide.
Topics: Animals; Anticonvulsants; Bicuculline; Brain; Cerebellum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ganglia, Spinal; Humans; In Vitro Techniques; Lethal Dose 50; Male; Mice; Rats; Schiff Bases | 1980 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Involvement of a GABAergic mechanism in the pharmacologic action of phenytoin.
Topics: Animals; Anticonvulsants; Baclofen; Electroshock; gamma-Aminobutyric Acid; Male; Mice; Phenytoin; Postural Balance; Seizures | 1986 |
Penicillin spikes in rats. Limitations of a simple model for the study of anticonvulsants.
Topics: Action Potentials; Animals; Anticonvulsants; Dimethyl Sulfoxide; Disease Models, Animal; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Isoxazoles; Male; Penicillins; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Taurine; Time Factors | 1984 |