phenytoin has been researched along with proadifen in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (88.89) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Karasawa, T; Masuda, Y; Shimizu, M; Shiraishi, Y; Utsui, Y; Yoshida, K | 1 |
| Franklin, MR; James, RC | 1 |
| Belpaire, FM; Bogaert, MG; Chindavijak, B | 1 |
| Cucinell, SA; Dayton, PG; Perel, JM; Weiss, M | 1 |
| Blackham, A; Spencer, PS | 1 |
| Kutt, H; Verebely, K | 1 |
| Conard, GJ; Finger, KF; Haavik, CO | 1 |
| Sotaniemi, EA | 1 |
| Becker, BA; Harbison, RD | 2 |
| Calhoun, FJ; Schrogie, JJ; Tolson, WW | 1 |
| Arnold, K; Gerber, N | 1 |
| Glasson, B | 1 |
| Johansen, T; Jørgensen, L | 1 |
| Bellamy, G; Green, WL; Nakamura, Y | 1 |
| Ariyama, J; Furuno, H; Hirai, K; Koyama, J; Shimada, H; Simamura, E | 1 |
| Benz, FW; Nerland, DE | 1 |
18 other study(ies) available for phenytoin and proadifen
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Pharmacokinetic and pharmacodynamic tolerance of a new anticonvulsant agent (3-sulfamoylmethyl-1,2-benzisoxazole) compared to phenobarbital, diphenylhydantoin and carbamazepine in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Hexobarbital; Isoxazoles; Kinetics; Male; Oxazoles; Phenobarbital; Phenytoin; Proadifen; Rats; Sleep; Time Factors | 1979 |
The triphasic amphetamine lethal dose curve in mice and its possible relationship to drug metabolism.
Topics: Aging; Amphetamine; Animals; Anticonvulsants; Dextroamphetamine; Hexobarbital; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Microsomes, Liver; Phenytoin; Piperonyl Butoxide; Proadifen; Sleep | 1978 |
SKF 525A displaces drugs from serum alpha 1-acid glycoprotein binding sites.
Topics: Aminopyrine N-Demethylase; Animals; Dogs; Humans; Liver; Orosomucoid; Oxprenolol; Phenytoin; Proadifen; Propranolol; Protein Binding; Rats; Serum Albumin | 1987 |
Dose-dependence of drug plasma level decline in dogs.
Topics: Acetates; Animals; Barbiturates; Blood Proteins; Chlorine; Chromatography, Thin Layer; Dicumarol; Dogs; Kinetics; Liver; Muscles; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Probenecid; Receptors, Drug; Vitamin K | 1967 |
Response of female mice to anticonvulsants after pretreatment with sex steroids.
Topics: Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Drug Synergism; Female; Lynestrenol; Mestranol; Mice; Phenobarbital; Phenytoin; Proadifen | 1970 |
Metabolism of diphenylhydantoin by rat liver microsomes. I. characteristics of the reaction.
Topics: Adenosine Triphosphate; Animals; Azides; Biotransformation; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Diethylstilbestrol; Dimenhydrinate; Disulfiram; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isoniazid; Kinetics; Male; Methylene Blue; Microsomes, Liver; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Proadifen; Prochlorperazine; Rats; Sodium; Temperature | 1970 |
The relationship of 5,5-diphenylhydantoin metabolism to the species-specific induction of gingival hyperplasia in the rat.
Topics: Animals; Chromatography, Gas; Colorimetry; Female; Gingiva; Gingival Hyperplasia; Half-Life; Male; Metabolism; Phenytoin; Proadifen; Rats; Species Specificity | 1972 |
Effects of drug pretreatment on antipyrine levels in blood and tissues: an example of multiple drug interactions.
Topics: Animals; Antipyrine; Brain; Brain Chemistry; Drug Interactions; Enzyme Induction; Half-Life; Kinetics; Liver; Male; Phenobarbital; Phenytoin; Proadifen; Rats; Time Factors | 1973 |
Effects of phenobarbital or SKF 525A pretreatment on diphenylhydantoin disposition in pregnant mice.
Topics: Abnormalities, Drug-Induced; Adipose Tissue; Amniotic Fluid; Animals; Brain Chemistry; Carbon Isotopes; Chromatography, Thin Layer; Feces; Female; Fetus; Injections, Intraperitoneal; Liver; Mice; Mice, Inbred Strains; Muscles; Phenobarbital; Phenytoin; Placenta; Pregnancy; Pregnancy, Animal; Proadifen; Time Factors | 1971 |
Effect of phenobarbital and SKF 525A pretreatment on diphenylhydantoin teratogenicity in mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Depression, Chemical; Drug Synergism; Female; Fetal Diseases; Fetus; Mice; Phenobarbital; Phenytoin; Pregnancy; Pregnancy, Animal; Proadifen; Stimulation, Chemical | 1970 |
Effects of various drugs on the uterotropic response to mestranol and norethynodrel in the rat.
Topics: Aminosalicylic Acids; Animals; Chlorpromazine; Drug Synergism; Female; Imipramine; Mestranol; Norethynodrel; Organ Size; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Rats; Scopolamine; Tolbutamide; Uterus | 1971 |
Studies on the metabolism of diphenylhydantoin in mice.
Topics: Animals; Cycloheximide; Cytochromes; Hexobarbital; Hydroxyzine; Kinetics; Liver; Male; Mice; Microsomes; Organ Size; Paralysis; Phenytoin; Proadifen; Sleep; Zoxazolamine | 1969 |
[Services and perspectives of metabolic research on certain exogenous substances endowed with pharmacological activity].
Topics: Animals; Carbon Tetrachloride Poisoning; Humans; Microsomes; Pentobarbital; Pharmacology; Phenobarbital; Phenytoin; Proadifen; Rats; Substance-Related Disorders | 1965 |
Affinity of drugs for cytochrome P-450 determined by inhibition of p-nitrophenetole O-deethylation by rat liver microsomes.
Topics: Animals; Biotransformation; Carbon Monoxide; Chloramphenicol; Cytochrome P-450 Enzyme System; Disulfiram; Drug Interactions; Isoniazid; Kinetics; Male; Microsomes, Liver; Nitrobenzenes; Nitrophenols; Oxidation-Reduction; Phenytoin; Proadifen; Rats; Rats, Inbred Strains | 1983 |
Effects of an inhibitor of hepatic drug metabolism, 2-diethylaminoethyl-2,2-diphenylvalerate HCl (SKF 525-A), on thyroxine metabolism in the rat.
Topics: Anaerobiosis; Animals; In Vitro Techniques; Kinetics; Liver; Male; Phenytoin; Proadifen; Rats; Structure-Activity Relationship; Thyroidectomy; Thyrotropin; Thyroxine | 1981 |
Paraquat detoxicative system in the mouse liver postmitochondrial fraction.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cobalt; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred ICR; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Paraquat; Phenobarbital; Phenytoin; Proadifen; Rabbits; Rifampin; Troleandomycin; Vitamin E | 2002 |
Effect of cytochrome P450 inhibitors and anticonvulsants on the acute toxicity of acrylonitrile.
Topics: Acrylonitrile; Animals; Anticonvulsants; Carcinogens; Central Nervous System Depressants; Cyanides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Ethanol; Imidazoles; Male; Phenobarbital; Phenytoin; Proadifen; Rats; Rats, Sprague-Dawley; Seizures; Time Factors | 2005 |