phenytoin has been researched along with primidone in 620 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 559 (90.16) | 18.7374 |
| 1990's | 31 (5.00) | 18.2507 |
| 2000's | 18 (2.90) | 29.6817 |
| 2010's | 12 (1.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bohlen, N; Hertl, M | 1 |
| Eadie, MJ; Lander, CM; Tyrer, JH | 1 |
| Roger, J; Tassinari, CA | 1 |
| Fayle, SA; Leppik, IE; McAuliffe, JJ; Pippenger, CE; Sherwin, AL | 1 |
| Richens, A | 2 |
| Kabra, PM; Marton, LJ; Stafford, BE | 1 |
| Smith, RF | 1 |
| Callaghan, N; Duggan, PF; Feely, M; O'Callaghan, M | 1 |
| Driessen, OM; Goedhart, DM; Meijer, JW | 1 |
| Buchthal, A | 1 |
| Lawrence, RC; Lovering, EG; Watson, JR | 1 |
| Dittrich, P; Müller, E; Wutke, K | 1 |
| Eickhoff, K; Heipertz, R; Poser, W | 1 |
| Brechbühler, T; Schweizer, K; Wick, H | 1 |
| Egli, M | 1 |
| Dreifuss, FE | 2 |
| Mohrbacher, RJ; Riendeau, CJ; Werner, M | 1 |
| Chadwick, D; Jenner, P; Reynolds, EH | 1 |
| Cameron, JD; Hedley, DW | 1 |
| Ludwig, BI; Marsan, CA | 1 |
| Kutt, H | 4 |
| Schmidt, D | 6 |
| Chadwick, D; Galbraith, AW; Reynolds, EH | 1 |
| Hopkins, A; Scambler, G | 1 |
| Johnson, RH; Lambie, DG; Nanda, RN; Shakir, RA | 1 |
| Abarbanel, J; Eylath, U; Herishanu, Y; Rosenberg, P | 1 |
| Laundy, M; Reynolds, EH | 1 |
| Fichsel, H; Knöpfle, G | 2 |
| Brune, GG; Matz, DR; Rolf, LH | 1 |
| Howland, C; McLean, AE; White, SJ | 1 |
| Penin, H | 1 |
| Oettinger, B; Richter, K | 2 |
| Deisenhammer, E; Sommer, R | 2 |
| Rambeck, B | 1 |
| Aucamp, AK | 1 |
| French, JH; McGregor, PA; Pippenger, CE; Rowan, AJ | 1 |
| Feldman, RG | 1 |
| Lison, MP; Speciali, GG | 1 |
| Livingston, S; Pauli, LL; Pruce, I | 2 |
| Albani, M; Gauchel, FD; Toseland, PA | 1 |
| Plaa, GL | 1 |
| Horton, RW; Meldrum, BS; Toseland, PA | 1 |
| Glazko, AJ | 1 |
| Ahmad, S; Houghton, GW; Laidlaw, J; Richens, A | 1 |
| Müller-Oerlinghausen, B | 1 |
| Stores, G | 1 |
| McClean, SW; Rodbard, D | 1 |
| McClean, SW; Yonekawa, W; Young, DS | 1 |
| Brown, L; Horning, MG; Kellaway, P; Lertratanangkoon, K; Nowlin, J; Zion, TE | 1 |
| Adams, RF | 1 |
| Sauer, W; Windorfer, A | 1 |
| Hammond, KB | 1 |
| Stünkel, S; Weinmann, HM; Windorfer, A | 1 |
| Gascon Barré, M | 1 |
| Turri, JJ | 1 |
| Haeckel, R; Heyer, R; Külpmann, WR; Oellerich, M | 1 |
| Klotz, U | 1 |
| Helenius, T; Liewendahl, K; Majuri, H | 1 |
| Karbowski, K | 2 |
| Mimaya, H | 1 |
| Conomy, JP | 1 |
| Miyamura, S; Yamada, M | 1 |
| Göbel, W; Löscher, W | 1 |
| Bruni, J | 2 |
| Campbell, DJ; Godolphin, W; Urquhart, N | 1 |
| Newmark, ME; Penry, JK | 1 |
| Reith, H; Schäfer, H | 1 |
| Crawford, RD; Davis, HL; Johnson, DD | 1 |
| Berchou, RC; Lodi, RA; Sherman, JA | 1 |
| Fretthold, DW; Kumar, S; Pesh-Imam, M; Sunshine, I; Terrentine, S; Willis, CE | 1 |
| Livingston, S | 2 |
| Friis, ML | 2 |
| Stünkel, S; Windorfer, A | 1 |
| Freeman, DJ; Rawal, N | 1 |
| Dymling, JF; Lidgren, L; Wallöe, A | 1 |
| Burk, PG; Nathanson, G; Pollack, MA | 1 |
| Franks, RD; Richter, AJ | 1 |
| Anglim, MA; Dolar, E; Least, CJ; St Onge, LM | 1 |
| Fröscher, W | 1 |
| Takamatsu, N | 1 |
| Rylance, GW | 1 |
| Wilkinson, HA | 1 |
| Abraham, CV; Gresham, D | 1 |
| Varma, R | 2 |
| Kaneko, S | 2 |
| Castro, A; Jatlow, PI; Malkus, H | 1 |
| Plenge, KL | 1 |
| Hadden, DR; Maclay, E; McIlrath, EM; Nesbitt, GS | 1 |
| Rosenmund, H; Wad, N | 1 |
| Burke, DG; Halpern, B; Korth, J; Summons, R; Truscott, RJ | 1 |
| Hewitt, TE; Kessler, G; Sievers, DL | 1 |
| Guelen, P; Knop, H; Schobten, F; van der Kleijn, E; Vree, T; Westenberg, H | 1 |
| Flanagan, RJ; Rutherford, DM | 1 |
| Christiansen, J; Friis, ML; Hvidberg, EF | 1 |
| Alpert, JN | 1 |
| Gebhart, E | 1 |
| Perucca, E; Richens, A | 1 |
| Müller-Oerlinghausen, B; Riedel, E | 1 |
| Brachet, A; Henry, P; Loiseau, P | 1 |
| Wilson, JT | 2 |
| Dam, M; Hvidberg, EF | 1 |
| Bowers, MB; Cohen, DJ; Shaywitz, BA | 1 |
| Ferry, D; Ferry, DG; McQueen, EG | 1 |
| Freeman, JM; Singer, HS | 1 |
| Kupferberg, HJ; Sutton, G | 1 |
| Dekaban, AS; Lehman, EJ | 1 |
| Bolin, RH; Bruya, MA | 1 |
| Goodman, RM; Hertz, M; Katznelson, D; Katznelson, MB; Rotem, Y | 1 |
| Knotts, GR; Thomas, JA | 1 |
| Andersen, P; Moseklide, L | 1 |
| Bruce, AM; Smith, H | 2 |
| Johnson, GF; Least, CJ; Solomon, HM | 2 |
| Ayers, GJ; Burnett, D; Goudie, JH; Reed, K | 1 |
| Hill, RE; Latham, AN | 1 |
| Bill, P; Buchanan, N; Eyberg, C; Fernandes Costa, F; Moodley, GP; Strickwold, B | 1 |
| Ashworth, B; Horn, DB | 1 |
| Eickhoff, K; Heipertz, R; Pilz, H | 1 |
| Bius, DL; Boyles, LW; Dudley, KH; Kraus, BL | 1 |
| Bartels, H; Kruse, K; Oldigs, HD | 1 |
| McElhatton, PR; Sullivan, FM | 2 |
| Callaghan, N; Duggan, F; Feely, M; O'Callaghan, M; Seldrup, J | 1 |
| Brachet-Liermain, A; Centraud, B; Loiseau, P | 1 |
| Cameron, JD; Chambers, RE | 1 |
| Iwai, H; Kubo, S; Kuyama, C; Watanabe, S; Yokoyama, S | 1 |
| Florey, JB; Goller, VL; Klein, GL; Larese, RJ; Van Meter, QL | 1 |
| Abraham, CV | 1 |
| Adams, RF; Vandemark, FL | 2 |
| Johnson, GF; Least, CJ; Serum, JW; Solomon, HM; Solow, EB | 1 |
| Ionasescu, V; Waziri, M; Zellweger, H | 1 |
| Chadwick, D; Fairhurst, E; Reynolds, EH; Ridge, BD | 1 |
| Boldyrev, AI; Vaĭntrub, MIa | 1 |
| Latham, AN; Varlow, G | 1 |
| Karmen, A; Lehrer, M | 1 |
| Cramers, CA; Hulsman, JA; Meijers, CA; van Kuik, LG; Vermeer, EA | 1 |
| Kitamura, M; Nishina, T; Okoshi, K | 1 |
| Abraham, CV; Joslin, HD | 2 |
| Chadwick, D; Marsden, CD; Reynolds, EH | 1 |
| Oettinger, B | 1 |
| Bailey, DG; Davis, HL; Johnson, GE; Wilson, TW | 1 |
| Coulthard, MG | 1 |
| Gädeke, R; Sauer, W; Windorfer, A | 1 |
| Monroe, RR | 1 |
| Ajmone-Marsan, C; Mutsuga, N; Sadowsky, D; Van Buren, JM | 1 |
| Friel, P; Troupin, AS | 2 |
| Gädeke, R; Sauer, M; Windorfer, A | 2 |
| Fenton, G; Fenwick, P; Johnson, AL; Laundy, M; Reynolds, EH | 1 |
| Baars, I; Guelen, PJ; Kleijn, E; Vree, TB | 1 |
| Bailey, DG; Davis, HL; Falk, KJ | 1 |
| Bishun, NP; Smith, NS; Williams, DC | 1 |
| Bosl, R; Buselmeier, TJ; Kjellstrand, CM; Meyer, RM; Shideman, JR; von Hartitzsch, B | 1 |
| Joern, WA | 1 |
| Blaskovics, ME; Podosin, RL; Roe, TF | 1 |
| Harley, JP; Matthews, CG | 1 |
| Aderet, NB; Biale, Y; Lewenthal, H | 1 |
| DuCharme, LL; Farquhar, JA; Huntsman, BJ; Lockard, JS; Uhlir, V | 1 |
| Wehrhahn, L; Wiegrebe, W | 1 |
| Schlunegger, UP; Wehrhahn, L; Wiegrebe, W | 1 |
| Bachelard, HS; Polkey, CE; Thompson, MF | 1 |
| Chadwick, D; Chanarin, I; Jenner, P; Reynolds, EH | 1 |
| Booker, HE | 1 |
| Annegers, JF; Elveback, LR; Hauser, WA; Kurland, LT | 2 |
| Cate JC, IV; Tenser, R | 1 |
| Kupferberg, J; Schmidt, D | 1 |
| Davidson, S; Houghton, GW; Richens, A; Toseland, PA | 1 |
| Borst, SI; Lockwood, CH | 1 |
| Legaz, M; Raisys, VA | 1 |
| Buddington, R; Daly, DD; Penry, JK; Pippenger, CE; White, BG | 1 |
| Gotelli, G; Kabra, PM; Marton, LJ; Stanfill, R | 1 |
| Hill, JG; Soldin, SJ | 1 |
| Dorrity, F; Linnoila, M | 1 |
| Goto, T; Ito, K; Kobayashi, Y; Owada, E; Sakuta, N; Sato, J; Sekizawa, Y; Yoshida, A; Yoshihara, M | 1 |
| Watanabe, M; Yagi, K | 1 |
| Burlina, A; Mould, GP; Müller, C; Stamp, RJ | 1 |
| Eadie, MJ | 1 |
| Modica, PA; Spitznagel, EL; Tempelhoff, R | 1 |
| Matisová, E; Pham Thi, Ha; Volmut, J | 1 |
| Haginaka, J; Kimura, Y; Wakai, J; Yasuda, H | 1 |
| Bausch, S; Blackwood, J; Gassmann, S; Grün, K; Inbar, S; Kreider, R; Löchel, B; Siebert, M; Walter, G | 1 |
| Ruser, I | 1 |
| Cramer, JA; Mattson, RH; McCutchen, CB | 1 |
| Knott, C; Reynolds, F | 2 |
| Lishman, WA; Ramana, R; Silverstone, PH | 1 |
| Baldwin, BH; Bunch, SE; Castleman, WL; Hornbuckle, WE; Tennant, BC | 1 |
| Macdonald, RL; McLean, MJ | 1 |
| Higashi, A; Inotsume, N; Kinoshita, E; Matsuoka, T; Nakano, M | 1 |
| Braide, SA; Davies, TJ | 1 |
| Hartshorn, EA; Hartshorn, JC | 1 |
| Canevini, MP; Canger, R; Cornaggia, CM; Giuccioli, D; Pruneri, C | 1 |
| Berry, DJ; Newbery, JE; Pettit, LI; Streete, JM | 1 |
| Baciewicz, AM | 1 |
| Shinnar, S | 1 |
| Bourgeois, BF | 1 |
| Collins, JF; Cramer, JA; Mattson, RH | 1 |
| Reininghaus, R; Schmidt, D; Winkel, R | 1 |
| Collins, JF; Craft, B; Cramer, JA; Mattson, RH; Novelly, RA; Smith, DB | 1 |
| Borromei, A; Caramelli, R; Cipriani, G; Giancola, LC; Guerra, L; Lozito, A | 1 |
| Frankel, RJ; Henry, JA; Minton, NA | 1 |
| Spina, E; Tomson, T; Wedlund, JE | 1 |
| Baldwin, BH; Bunch, SE; Castleman, WL; Center, SA; Conway, MB; Hornbuckle, WE; Tennant, BC | 1 |
| Caron, G; Sheehan, M | 1 |
| Stefan, H | 1 |
| Levy, RH; Yerby, MS | 1 |
| Browne, TR; Collins, JF; Cramer, JA; Delgado-Escueta, AV; Mattson, RH; McCutchen, CB; McNamara, JO; Smith, DB; Treiman, DM; Williamson, PD | 1 |
| Ishizaki, T; Kushida, K | 1 |
| Burke, JT; Thénot, JP | 1 |
| Canevini, MP; Canger, R; Cornaggia, C; Giuccioli, D; Pinelli, P; Pruneri, C | 1 |
| Frey, HH; Löscher, W | 1 |
| György, I; Ilyés, I; Kirilina, S; Tornai, A | 1 |
| Richter, K; Schmidt, D | 1 |
| Hirayama, Y; Koide, Y; Moroka, K; Oka, S; Suzuki, H | 1 |
| Bonin, P; Casara, GL; Furlanut, M; Montanari, G | 1 |
| Diem, E; Granditsch, G; Muhar, U | 1 |
| DiMarzio, JM; Fisher, SJ; George, H; Horton, CM; Kurtz, SR | 1 |
| Baylis, EM; Crowley, JM; Marks, V; Preece, JM; Sylvester, PE | 1 |
| Lowe, CR | 1 |
| Reynolds, EH | 5 |
| Davidson, S; Falconer, MA | 1 |
| Clemmesen, J; Fuglsang-Frederiksen, V; Plum, CM | 1 |
| Kutt, H; Penry, JK | 1 |
| Bochentin, W; Koeppe, P; Kraft, D; Opitz, A; Schaefer, K; von Herrath, D | 1 |
| Fischer, HU; Schütze, I | 1 |
| Kyogoku, Y; Yu, NT | 1 |
| Laitinen, L; Toivakka, E | 1 |
| Sibley, WA | 1 |
| McLellan, DL; Swash, M | 1 |
| Davies, TJ; Kupersmitt, E; Orme, M; Petrie, A; Silver, J; Vajda, F | 1 |
| Davidson, DC; Ford, JA; McIntosh, WB | 1 |
| Parsonage, M | 1 |
| Matthews, DM; Reynolds, EH | 1 |
| Chanarin, I; Matthews, DM; Reynolds, EH | 1 |
| Afifi, AK; Van Allen, MW | 1 |
| Discombe, C; Evans, AR; Forrester, RM | 1 |
| Dano, P | 1 |
| Salomon, B; Schütze, I; Thal, W | 1 |
| Fehling, C; Jägerstad, M; Lindstrand, K; Westesson, AK | 1 |
| Meyer, JG | 2 |
| Brill, PW; Leonidas, JC; Waldman, N | 1 |
| Billinghurst, JR; German, GA; Orley, JH | 1 |
| Leary, PM | 1 |
| Brock, JT; Cereghino, JJ; Ellenberg, J; Fisher, P; Penry, JK; Smith, LD; Van Meter, JC | 1 |
| Gold, AP | 1 |
| Christiansen, C; Rodbro, P; Sjö, O | 1 |
| Mitterstieler, G; Schwingshackl, A; Waltl, H | 1 |
| Hensley, WJ; Huang, CY; McLeod, JG; Sampson, D | 2 |
| Forman, PM | 1 |
| Lossing, JH; Saper, JR | 1 |
| Janz, D | 1 |
| Lehtovaara, R | 2 |
| Taguchi, H | 1 |
| Millichap, JG | 3 |
| Delling, G; Lücking, T | 1 |
| Eisen, AA; Sherwin, AL; Woods, JF | 1 |
| Freeman, JM; Lietman, PS | 1 |
| Hooshmand, H | 1 |
| Liu, MC | 1 |
| Sayers, A; Stille, G | 1 |
| Rümke, CL | 1 |
| Gibberd, FB | 1 |
| Wilson, J | 1 |
| Rowan, AJ; Scott, D | 1 |
| Mandel, HG; Riis, M | 1 |
| Gardner-Thorpe, C; Parsonage, MJ; Toothill, C | 1 |
| Ente, G; Pochedly, C | 1 |
| Kutt, H; Louis, S | 1 |
| Spector, RG | 1 |
| Röttger, HJ; Windorfer, A | 1 |
| Ballinger, BR; Simpson, E; Stewart, MJ | 1 |
| Livingston, S; Pauli, LL | 1 |
| Bowden, AN; Livingston, S; Pauli, LL | 1 |
| Fenton, GM; Laundy, M; Reynolds, EH; Slavin, BN | 1 |
| Bredesen, JE; Johannessen, SI | 1 |
| Beam, RE | 1 |
| Cavazzuti, GB | 1 |
| Windorfer, A | 1 |
| Hilgartner, MW; Kutt, H; Solomon, GE | 1 |
| Bock, GW; Loynd, JS; Sherwin, AL; Sokolowski, CD | 1 |
| Neville, BG | 1 |
| Garrettson, LK | 1 |
| Grinberg, KN; Shapiro, IuL; Vaĭntrub, MIa; Zhurkov, VS | 1 |
| Gallagher, BB; Glass, D; Mattson, RH; Reynolds, EH | 1 |
| Birket-Smith, E; Holm, P; Lund, M; Mikkelsen, B; Olsen, PZ; Vestermark, S | 1 |
| Zellweger, H | 1 |
| Gregoriades, AD | 1 |
| Gallagher, BB; Reynolds, EH; Travers, RD | 1 |
| Dvilansky, A; Lehman, E | 1 |
| Clothier, B; Rundle, AT; Sudell, B | 1 |
| Horne, PD | 1 |
| Flury, W | 1 |
| Gallagher, BB; Mattson, RH; Reynolds, EH | 1 |
| Green, JB; Solow, EB | 1 |
| Amin, I; Cooper, IS; Crighel, E | 1 |
| Burnett, D; Goudie, JH | 1 |
| Haerer, AF; Hull, RP | 1 |
| Rundle, AT; Sudell, B | 1 |
| Rodgers, G; Roger, JC; Soo, A | 1 |
| Perchalski, RJ; Wilder, BJ | 2 |
| Berardi, AC; Izquierdo, I; Orsingher, OA | 1 |
| Wilkinson, GR; Wilson, JT | 2 |
| Panther, W | 1 |
| Slomic, A; Szöts, F | 1 |
| Lifshitz, F; Maclaren, NK | 1 |
| Latham, AN; Richens, A | 1 |
| Baumel, IP; Gallagher, BB; Mattson, RH; Woodbury, SG | 1 |
| Brock, JT; Cereghino, JJ; Meter, JC; Penry, JK; Smith, LD; White, BG | 1 |
| Fincham, RW; Schottelius, DD | 1 |
| Butler, C; Harvey, DJ; Hill, RM; Horning, MG; Zion, TE | 1 |
| Schlack, HG; Vogt, HJ | 1 |
| Henriksen, O; Loyning, Y | 1 |
| Hammer, RH; Perchalski, RJ; Scott, KN; Wilder, BJ | 1 |
| Cremers, HM; Verheesen, PE | 1 |
| Christiansen, C; Lund, M; Rodbro, P | 1 |
| Jamison, DL | 1 |
| Skrotskiĭ, IuA | 1 |
| Heischkeil, R | 1 |
| Fincham, RW; Sahs, AL; Schottelius, DD | 2 |
| Baylis, EM; Fry, DE; Marks, V; Papadopoulos, AS | 1 |
| Medlinsky, HL | 1 |
| Hill, RM; Horning, MG; McCulley, LB; Morgan, NF; Verniaud, WM | 1 |
| Metaxas, JM; Solow, EB; Summers, TR | 1 |
| Arakawa, T; Karahashi, M; Takagi, T; Tanabu, M; Yoshida, T | 2 |
| Reynolds, EH; Travers, RD | 1 |
| Breckenridge, A; Davidson, S; Falconer, MA; Vajda, F; Williams, FM | 1 |
| Kurata, D; Wilkinson, GR | 1 |
| Jensen, ON; Olesen, OV | 2 |
| Ristić, J | 1 |
| Aymat, F; Milichap, JG | 1 |
| Borkowska, Z; Mazurkowa, K; Wojakowski, A | 1 |
| el-Masry, AM; Saad, SF; Scott, PM | 1 |
| Bower, BD | 1 |
| Haining, RG; Labbé, RF; Lefebvre, EB | 1 |
| Berry, DJ; Grove, J; Toseland, PA | 1 |
| Naess, K | 1 |
| De Luca, K; Masotti, RE; Partington, MW | 1 |
| Borgstedt, AD; Bryson, MF; Forbes, GB; Young, LW | 1 |
| Gardner-Thorpe, C; Parsonage, MJ; Smethurst, PF; Toothill, C | 1 |
| Majkowski, J | 2 |
| Genuth, SM; King, KC; Klein, L; Rabinovich, S | 1 |
| Kupferberg, HJ | 2 |
| Harms, D | 1 |
| Dennis, NR | 1 |
| Cendrowski, W; Majkowski, J | 1 |
| Trautmann, A | 1 |
| Caratzali, A; Roman, IC | 1 |
| Fuglsang-Fredriksen, V; Linde, J; Molholm Hansen, J; Siersbaek-Nielsen, K | 1 |
| Gallagher, BB; Glaser, GH; Travers, RD | 1 |
| Marques-Assis, L | 1 |
| Chanarin, I; Matthews, DM; Milner, G; Reynolds, EH | 1 |
| Huisman, JW; van Heycop ten Ham, MW; van Zijl, CH | 1 |
| Booker, HE; Burdette, RD; Darcey, B; Hosokowa, K | 1 |
| Golden, GS | 1 |
| Hommes, OR; Houben, PF; Knaven, PJ | 1 |
| Dent, CE; Richens, A; Rowe, DJ; Stamp, TC | 1 |
| Norton, J; Plott, D; White, PT | 1 |
| Viukari, NM | 1 |
| Matti, N; Tammisto, P; Viukari, A | 1 |
| Tammisto, P; Viukari, NM | 1 |
| Darcey, B; Evenson, MA; Jones, P | 1 |
| Buckmaster, HS; Shelley, LL; Van Meter, JC | 1 |
| Blumer, D; Holscher, E; Niedermeyer, E; Walker, BA | 1 |
| Richens, A; Rowe, DJ | 1 |
| Laurance, BM | 1 |
| Kocen, RS; Lascelles, PT; Reynolds, EH | 1 |
| Heyndrickx, A; Okkerse, E; Van Hoof, F | 1 |
| Brown, GL; Wilson, WP | 1 |
| Fletcher, BD; Lussier-Lazaroff, J | 1 |
| Elshove, J; van Eck, JH | 1 |
| Harasymiv, I; Hensley, WJ; Sampson, D | 1 |
| Meinardi, H | 1 |
| Endröczi, E; Fekete, T | 1 |
| McGregor, JG; Schreiber, MM | 1 |
| Gordon, N | 1 |
| Elsborg, L | 1 |
| Blair, AA; Hallpike, JF; Lascelles, PT; Wingate, DL | 1 |
| Breuer, U; Lempp, R | 1 |
| Jenny, E; Solberg, R | 1 |
| Lou, HO | 1 |
| Gillen, HW; Pippenger, CE; Scott, JE | 1 |
| Spilker, B; Yeager, CL | 1 |
| Peters, BH; Samaan, NA | 1 |
| Gillen, HW; Pippenger, CE | 1 |
| Dayton, PG; Garrettson, LK; Perel, JM | 1 |
| Collins, AJ; Horlington, M | 1 |
| Huisman, JW | 1 |
| Ahuja, GK; Schumacher, GA | 1 |
| Olesen, OV | 2 |
| Tollefson, G | 1 |
| Maheshwari, MC | 1 |
| Bruni, J; Wilder, BJ | 1 |
| Deisenhammer, E; Schwarzbach, H; Sommer, R | 1 |
| Neuvonen, PJ; Tokola, RA | 1 |
| Hosokawa, K; Kugoh, T | 1 |
| Brune, GG; Nautsch, JP; Rolf, LH | 1 |
| Monninger, P; Przuntek, H | 1 |
| Berlit, P; Krause, KH; Rascher, W | 1 |
| Hobusch, D; Külz, J | 1 |
| Kiul'ts, I; Klaĭf, F | 1 |
| Crout, BO; Gross, JA; Swift, TR; Ward, LC | 1 |
| Reynolds, EH; Shorvon, SD | 2 |
| Dietzler, DN; Hoelting, CR; Leckie, MP; Porter, SE; Smith, CH; Tieber, VL | 1 |
| Cramer, JA; Delgado Escueta, AV; Mattson, RH; Smith, DB | 1 |
| Aicardi, J; Vajda, FJ | 1 |
| Haven, GT; Kiser, EJ; Studts, D | 1 |
| Ou, CN; Rognerud, CL | 1 |
| Janz, D; Schmidt, D; Tsai, JJ | 1 |
| Göpfert-Geyer, I; Hartmann, A; Helge, H; Huth, H; Jäger-Roman, E; Jakob, S; Koch, S; Rating, D | 1 |
| Rowan, AJ | 1 |
| Crema, A; Perucca, E | 1 |
| Callaghan, N; Keating, J; O'Dwyer, R | 1 |
| Albright, PS; Bruni, J | 1 |
| Helge, H; Jäger-Roman, E; Kuhnz, W; Nau, H; Rating, D | 1 |
| Hedges, A; Makki, KA; Perucca, E; Richens, A; Ruprah, M; Wilson, JF | 1 |
| Alonso, RJ; Covington, TR; Mancall, EL | 1 |
| De Paiva, VJ; Subirana, A; Subirana, M | 1 |
| Forsythe, WI; Sills, MA | 1 |
| Gathman, G; Herrick, MK; Mallow, DW | 1 |
| Painter, MJ; Pippenger, CE; Powell, C | 1 |
| Andriolo, A; Germek, OA; Pereira, AB | 1 |
| Berlit, P; Bonjour, JP; Kochen, W; Krause, KH | 1 |
| Holmes, LB; Keith, DA; Krauss, CM; VanLang, Q | 1 |
| Friis, ML; Hvidberg, E | 1 |
| Chan, K; Lok, S; Teoh, R | 1 |
| Obe, G; Riedel, L | 1 |
| Trimble, MR | 1 |
| Brandt, T; Esser, J | 1 |
| Bennett, HS; Dunlop, T; Ziring, P | 1 |
| Börner, W; Hoffmann, R; Moll, E; Reiners, C | 1 |
| Collins, JF; Cramer, JA; Delgado Escueta, AV; Mattson, RH; Smith, DB | 1 |
| Bell, F; Chan, S; Gerson, B | 1 |
| Baldwin, BH; Bunch, SE; Hornbuckle, WE; Tennant, BC | 1 |
| Farnbach, GC | 1 |
| Deisenhammer, E; Nitsche, V; Sommer, R | 1 |
| Franco-Morselli, R; Morselli, PL | 1 |
| Kirkham, DB; Reynolds, NC | 1 |
| Kingsley, E; Tolman, KG; Tweedale, R | 1 |
| Quednow, B; Walther, H | 1 |
| Bittencourt, PR; Richens, A | 1 |
| Aminoff, MJ | 1 |
| Kulik, FA; Wilbur, R | 1 |
| Scollo-Lavizzari, G | 1 |
| Majkowski, J; Pisarski, W; Tokarz, A; Woźniak, J | 1 |
| Goodey, RJ | 1 |
| Cohan, SL | 1 |
| Koch, KM; Levy, RH | 1 |
| Richter, K; Scherber, A | 1 |
| Congdon, WC; DuCharme, LL; Levy, RH; Lockard, JS | 1 |
| Kido, H | 1 |
| Kabra, PM; Marton, LJ; Nelson, MA | 1 |
| Bartels, H; Günther, E; Wallis, S | 1 |
| Chiba, K; Ishizaki, T; Kushida, K | 1 |
| Johnson, RH; Lambie, DG | 2 |
| Neels, HM; Scharpé, SL; Totté, JA; Verkerk, RM; Vlietinck, AJ | 1 |
| Browne, TR; Szabo, GK | 1 |
| Meijer, JW; Rambeck, B; Riedmann, M | 1 |
| Schulman, J | 1 |
| Emmett, JR; Shea, JJ | 1 |
| Bannister, SJ; Dolan, JW; Snyder, LR; van der Wal, S | 1 |
| Külpmann, WR | 1 |
| Dietzler, DN; Hoelting, CR; Leckie, MP; Smith, CH; Tieber, VL | 1 |
| Holliday, TA | 1 |
| Lacher, DA; Savory, J; Sinn, JA; Wills, MR | 1 |
| Knight, D | 1 |
| Igari, J; Kanazawa, T; Takahashi, K | 1 |
| Külpmann, WR; Oellerich, M | 1 |
| Kupferberg, HJ; Newmark, ME; Porro, MG; Porter, RJ; Theodore, WH | 1 |
| Bunch, SE; Castleman, WL; Hornbuckle, WE; Tennant, BC | 1 |
| Assael, BM; Avanzini, G; Battino, D; Bossi, L; Caccamo, ML; Canger, R; Como, ML; de Giambattista, M; Franceschetti, S; Marini, A; Pardi, G; Pifarotti, G; Porro, MG; Rovei, V; Sanjuan, M; Soffientini, ME; Spina, S; Spreafico, R | 1 |
| Aguilera, L; Galdames, D; Ortiz, M; Saavedra, I | 1 |
| Arranz Peña, MI | 1 |
| Mattson, RH; Spencer, DD; Spencer, SS; Williamson, PD | 1 |
| Esser, KJ; Habedank, M; Kotlarek, F; Mühler, E; Mühler, U | 1 |
| Davis, CM; Fenimore, DC | 1 |
| Brügmann, G | 1 |
| Ahlfors, UG; Ebeling, P; Helenius, T; Liewendahl, K; Majuri, H | 1 |
| Maheshwari, MC; Padmini, R | 1 |
| Ahmad, SN; Jaffery, NF; Jailkhani, BL | 1 |
| Gross, AJ; Morton, WA; Saunders, S; Wannamaker, BB | 1 |
| Christofides, JA; Fry, DE | 1 |
| Cabrini, G; Marossero, F; Porro, MG; Ravagnati, L; Sironi, VA | 1 |
| Kumps, A; Mardens, Y | 1 |
| Soldin, SJ | 1 |
| Haidukewych, D; Rodin, EA | 1 |
| Bartels, H; Dreller, E; Kracht, U; Kruse, K | 1 |
| Hawkins, DB | 1 |
| Arko, K; Barbarić, V; Hajnsek, F | 1 |
| Sterman, MB | 1 |
| Mastropaolo, C; Monaco, F; Mutani, R; Piredda, S; Tondi, M | 1 |
| Cloyd, J; Garnett, WR; Holmes, GL; Meyer, MC; Schiffer, JR | 1 |
| Besse, CP; Handfield-Jones, SE; Jenkins, RE; McGibbon, DH; Whittaker, SJ | 1 |
| Gross-Selbeck, G | 1 |
| Branford, D; Collacott, RA | 1 |
| Buckoke, C; Davidson, C; Gutteridge, C; Laurenson, IF | 1 |
| Hekster, YA; Keyser, A; Lammers, MW; Meinardi, H; Renier, WO; van Lier, H; Wijsman, DJ | 1 |
| Schmutz, A; Thormann, W | 1 |
| Kucharczyk, N; Romanyshyn, LA; Shumaker, RC; Sofia, RD; Ward, D; Wichmann, JK | 1 |
| Haris, A; Radó, JP | 1 |
| Delgado, M; Eggers, CM; Forman, LJ; Liu, H; Montoya, JL | 1 |
| Ebner, A; Hermanns, G; Holthausen, H; Noachtar, S; Tuxhorn, I; Wolf, P | 1 |
| Helge, H; Jäger-Roman, E; Koch, S; Lösche, G; Nau, H; Rating, D | 1 |
| Perucca, E; Pisani, F; Spina, E | 1 |
| Luer, MS; Winkler, SR | 1 |
| Boothe, DM | 1 |
| Bourgeois, BF; Hasegawa, H; Hutson, P; Kanner, AM | 1 |
| Bates, D; Privitera, M; Warner, A | 1 |
| Schlienger, RG; Shear, NH | 1 |
| Chadwick, D | 1 |
| Chen, C; Cox, E; Fiedler-Kelly, J; Grasela, TH; Risner, ME; Womble, GP | 1 |
| Fukuhara, N; Ishida, C | 1 |
| Apeland, T; Kristensen, O; Mansoor, MA; Strandjord, RE | 1 |
| Bettendorf, U; Boenigk, HE; Borusiak, P; Karenfort, M; Korn-Merker, E | 1 |
| Jira, T; Menyes, U; Roth, U; Sokoliess, T | 1 |
| Laskowska, M; Leszczyńska-Gorzelak, B; Oleszczuk, J | 1 |
| Carvalho, D; Lanças, FM; Queiroz, ME; Silva, SM | 1 |
| GYDELL, K | 1 |
| BENIANS, RC; HUNTER, RA | 1 |
| POECK, K | 1 |
| BAER, RL; GOLDSTEIN, N; LEIDER, M | 1 |
| CHIESARA, E; KATO, R; VASSANELLI, P | 1 |
| BAILEY, AA | 1 |
| BOND, WH; CHILDRESS, RH; LONG, MT | 1 |
| CHALMERS, JN; HORSFIELD, GI | 1 |
| BOSE, BC; SAIFI, AQ; SHARMA, SK | 1 |
| HABOVICK, JA; MCCABE, WS | 1 |
| HENSON, RA | 1 |
| KLIPSTEIN, FA | 1 |
| ARIMA, M; FUKUYAMA, Y; NAGAHATA, M; OKADA, R | 1 |
| GIBBS, EL; GIBBS, FA; RICH, CL | 1 |
| KIORBOE, E | 1 |
| FITZGIBBON, JP; LISHMAN, WA; WHITTY, CW | 1 |
| DEVOTO, RA; PODESTA, LD; PRECERUTTI, AS | 1 |
| JONGMANS, JW | 1 |
| GRANT, WM; PECZON, JD | 1 |
| MEYER, HJ; MEYER-BURG, J | 1 |
| CHAREST, MP; DAVIS, MA; GAUDRY, R; HERR, F; THOMAS, RA; WINTHROP, SO | 1 |
| ANAND, MP | 1 |
| DAVIDSON, DS; MALLORY, GK; RODGERS, JB | 1 |
| CRAIG, WS; MACKINNON, JM | 1 |
| ZAKHARIIA, EA; ZAPADNIUK, VI | 1 |
| DEVERDIER, CH; HAMFELT, A; KILLANDER, A; MALERS, E | 1 |
| KOKENGE, R; KUTT, H; MCDOWELL, F | 1 |
| BALIER, C; MARCHAND, L; TEULIE, G | 1 |
| Blanco, CC; Carretero, AS; Casas, MN; Gutiérrez, AF | 1 |
| Gotti, R; Ronsisvalle, G; Santagati, NA | 1 |
| Li, JH; Rui, JZ; Xiang, BR; Zhao, Y | 1 |
| Ikuta, T; Itomi, S; Negoro, T; Okumura, A; Watanabe, K | 1 |
| Dahl, ML; Kimland, E; Tomson, T | 1 |
| Edelbroek, PM; Vermeij, TA | 1 |
| Apeland, T; Frøyland, ES; Kristensen, O; Mansoor, MA; Strandjord, RE | 1 |
| Malik, AK; Rani, S; Singh, B | 1 |
| Bialer, M | 1 |
| Dong, MM; Rosario-Ortiz, FL; Trenholm, R | 1 |
| Beydemir, Ş; Demir, Y | 1 |
| de Baat, C; Vissink, A; Zweers, PGMA | 1 |
| Acar, T; Alkan, G; Çaksen, H; Cander, B; Ergin, M; Ertekin, B; Koçak, S | 1 |
64 review(s) available for phenytoin and primidone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Interactions with antiepileptic drugs.
Topics: Acetaminophen; Acetazolamide; Anti-Anxiety Agents; Anticoagulants; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Furosemide; Gonadal Steroid Hormones; Griseofulvin; Humans; Phenobarbital; Phenytoin; Primidone; Thiazines; Urea; Valproic Acid; Vitamin D | 1977 |
[Pharmacotherapy of epilepsy. II].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines; Valproic Acid | 1978 |
[Long-term anticonvulsant therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Epilepsy; Ethosuximide; Humans; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Primidone; Spasms, Infantile; Status Epilepticus; Thyroid Gland | 1979 |
The medical treatment of epilepsy: initiation of drug therapy.
Topics: Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Bromides; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Acute toxicity of antiepileptic drugs.
Topics: Acute Disease; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Dogs; Humans; Phenobarbital; Phenytoin; Poisoning; Primidone; Thiazines | 1975 |
Behavioural effects of anti-epileptic drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Confusion; Disorders of Excessive Somnolence; Epilepsy; Ethosuximide; Humans; Hyperkinesis; Learning Disabilities; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Psychoses, Substance-Induced; Psychotropic Drugs; Thiazines | 1975 |
The determination of anticonvulsants in biological samples by use of high-pressure liquid chromatography.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Mathematics; Phenacetin; Phenobarbital; Phenytoin; Primidone; Spectrophotometry, Ultraviolet; Succinimides; Temperature | 1977 |
Drugs and children: methods for therapeutic monitoring.
Topics: Carbamazepine; Child; Child, Preschool; Chloramphenicol; Chromatography, Gas; Colorimetry; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Gentamicins; Humans; Immunoassay; Infant; Infant, Newborn; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Quality Control; Spectrophotometry; Sulfonamides; Theophylline | 1977 |
[Laboratory controls in long-term treatment with anticonvulsive drugs (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Intestinal Absorption; Male; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid | 1977 |
[Vitamin D: influence of anticonvulsant drugs on its metabolism].
Topics: Animals; Anticonvulsants; Dihydroxycholecalciferols; Humans; Hydroxycholecalciferols; Hydroxylation; Kidney; Liver; Phenobarbital; Phenytoin; Primidone; Vitamin D; Vitamin D Deficiency | 1977 |
[The psycho-motor epilepsy (author's transl)].
Topics: Adolescent; Adult; Brain Injuries; Carbamazepine; Child; Diagnosis, Differential; Diseases in Twins; Electroencephalography; Epilepsy, Temporal Lobe; Humans; Limbic System; Phenytoin; Primidone; Prognosis; Syncope | 1978 |
[Antiepileptics during pregnancy and lactation. Pharmacokinetic data].
Topics: Anticonvulsants; Bromides; Carbamazepine; Clonazepam; Diazepam; Ethosuximide; Female; Fetus; Humans; Kinetics; Lactation; Maternal-Fetal Exchange; Nitrazepam; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1979 |
The medical treatment of epilepsy: maintenance of drug therapy.
Topics: Adolescent; Adult; Anticonvulsants; Biological Availability; Bromides; Carbamazepine; Child; Dextroamphetamine; Drug Administration Schedule; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Menstruation; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1979 |
Pharmacological and biochemical studies in epileptic fowl.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Brain; Chickens; Disease Models, Animal; Ethosuximide; Female; Humans; Male; Mutation; Phenobarbital; Phenytoin; Photic Stimulation; Primidone; Seizures; Valproic Acid | 1979 |
Special problems for drugs used in children.
Topics: Aspirin; Child; Diazepam; Drug Therapy; Female; Humans; Infant; Pediatrics; Phenytoin; Primidone | 1976 |
Clinical pharmacokinetics of anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Interactions; Ethosuximide; Female; Humans; Hydantoins; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Kidney Diseases; Kinetics; Liver Diseases; Milk; Molecular Biology; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1976 |
[Neurotoxicity of antiepileptic drugs].
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Ethosuximide; Humans; Male; Nervous System; Nervous System Diseases; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1992 |
Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significance.
Topics: Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Humans; Mephenytoin; Mephobarbital; Oxcarbazepine; Phenytoin; Primidone; Valproic Acid | 1991 |
Anticonvulsant drugs: mechanisms of action.
Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Biomechanical Phenomena; Carbamazepine; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Phenytoin; Primidone; Succinimides; Synapses; Synaptic Transmission; Valproic Acid | 1986 |
Carbamazepine drug interactions.
Topics: Carbamazepine; Cimetidine; Dextropropoxyphene; Drug Interactions; Erythromycin; Humans; Isoniazid; Lithium; Phenobarbital; Phenytoin; Primidone; Protein Binding; Troleandomycin; Valproic Acid; Warfarin | 1986 |
Antiepileptic drugs in adolescents.
Topics: Adaptation, Psychological; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Sports; Valproic Acid | 1987 |
[Neurotraumatology and post-traumatic epilepsy. Prevention, treatment and long-term follow-up. Barbexaclone + phenobarbital (maliasin) versus diphenylhydantoin, phenobarbital, primidone, carbamazepine].
Topics: Adolescent; Adult; Anticonvulsants; Brain Injuries; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1987 |
Determination of antiepileptic drugs.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Chromatography, Liquid; Clonazepam; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Mephenytoin; Monitoring, Physiologic; Phenytoin; Primidone; Succinimides; Valproic Acid | 1985 |
Pharmacokinetics of anti-epileptic drugs in the dog: a review.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Clonazepam; Diazepam; Dog Diseases; Dogs; Epilepsy; Ethosuximide; Kinetics; Phenobarbital; Phenytoin; Primidone; Species Specificity; Trimethadione; Valproic Acid | 1985 |
Anticonvulsants, folic acid, and epilepsy.
Topics: Anemia, Macrocytic; Animals; Anticonvulsants; Blood-Brain Barrier; Chemical Phenomena; Chemistry; Epilepsies, Partial; Epilepsy; Folic Acid; Humans; Leucovorin; Mice; Phenobarbital; Phenytoin; Primidone; Rabbits; Rats; Seizures | 1973 |
Usefulness of blood levels of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines | 1974 |
Diagnosis and treatment of epilepsy: overview and general principles.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Histamine H1 Antagonists; Humans; Hydantoins; Hypnotics and Sedatives; Infant, Newborn; Myoclonus; Phenobarbital; Phenytoin; Primidone; Sleep | 1974 |
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Electroshock; Epilepsy; Ethosuximide; Humans; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Seizures; Trimethadione; Urea | 1969 |
A basic approach to the understanding of seizures and the mechanism of action and metabolism of anticonvulsants.
Topics: Acetylcholine; Aminobutyrates; Anticonvulsants; Calcium; Cell Membrane Permeability; Depression, Chemical; Diazepam; Epilepsy; Ethosuximide; Humans; Membrane Potentials; Mephobarbital; Neural Inhibition; Neurons; Phenobarbital; Phenytoin; Primidone; Seizures; Stimulation, Chemical; Synapses; Synaptic Transmission | 1973 |
Toxic effects of anticonvulsants: general principles.
Topics: Adrenocorticotropic Hormone; Adult; Anticonvulsants; Benzodiazepinones; Body Surface Area; Body Weight; Carbamazepine; Child; Chlorobenzenes; Diagnosis, Differential; Diazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Half-Life; Humans; Nitro Compounds; Phenobarbital; Phenytoin; Primidone; Succinimides; Tranquilizing Agents; Trimethadione | 1974 |
The management of children with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsy; Ethosuximide; Humans; Infant; Infant, Newborn; Phenobarbital; Phenytoin; Primidone; Thiazines | 1970 |
Adverse hematologic effects of drugs.
Topics: Anemia, Hemolytic; Anemia, Macrocytic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Aspirin; Blood Platelet Disorders; Drug-Related Side Effects and Adverse Reactions; Female; Glucosephosphate Dehydrogenase Deficiency; Hematologic Diseases; Hematopoiesis; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Infant, Newborn; Infant, Newborn, Diseases; Phenobarbital; Phenytoin; Pregnancy; Primidone; Serum Sickness; Splenomegaly; Thrombocytopenia; Tranquilizing Agents | 1972 |
Pharmacology of anticonvulsants.
Topics: Animals; Anticonvulsants; Child; Drug Interactions; Electroencephalography; Ethosuximide; Half-Life; Humans; Liver; Mephobarbital; Phenobarbital; Phenytoin; Primidone | 1972 |
[Teratogenic and mutagenic effects of anticonvulsive and psychotropic drugs (review of the literature)].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Antidepressive Agents; Arm; Barbiturates; Chlorpromazine; Chromosome Aberrations; Chromosome Disorders; Cricetinae; Drosophila; Female; Heart Defects, Congenital; Humans; Imipramine; Infant, Newborn; Jaundice, Neonatal; Mutagens; Perphenazine; Phenothiazines; Phenytoin; Pregnancy; Primidone; Rabbits; Thalidomide; Tranquilizing Agents; Trifluoperazine | 1972 |
Cerebrospinal folate levels in epileptics and their response to folate therapy.
Topics: Anticonvulsants; Blood-Brain Barrier; Clinical Trials as Topic; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Tetrahydrofolates; Vitamin B 12 | 1974 |
Anticonvulsants during pregnancy: a danger to the developing fetus?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Barbiturates; Blood Coagulation Disorders; Chromosome Aberrations; Chromosome Disorders; Female; Fetus; Folic Acid; Humans; Infant, Newborn; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Succinimides; Trimethadione; Vitamin K; Vitamin K Deficiency Bleeding | 1974 |
The use of blood levels of antiepileptic drugs in clinical practice.
Topics: Administration, Oral; Adult; Anticonvulsants; Biopharmaceutics; Carbamazepine; Child; Drug Tolerance; Epilepsy; Ethosuximide; Humans; Injections, Intramuscular; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Sleep; Time Factors | 1974 |
Pharmacodynamic and pharmacokinetic measurements of antiepileptic drugs.
Topics: Anticonvulsants; Chromatography, Gas; Dose-Response Relationship, Drug; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1974 |
Osteomalacia and anticonvulsant drugs.
Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Epilepsy; Folic Acid; Humans; Liver; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Vitamin D | 1971 |
[General review of the present therapy of epilepsy].
Topics: Anticonvulsants; Barbiturates; Chlordiazepoxide; Diazepam; Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Succinimides | 1971 |
[Anticonvulsants and their side effects. II. Side effects].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Humans; Phenytoin; Primidone; Succinimides; Valproic Acid | 1980 |
Reassessment of the concept of a therapeutic range of anticonvulsant plasma levels.
Topics: Anticonvulsants; Binding Sites; Brain Chemistry; Carbamazepine; Drug Therapy, Combination; Genetic Variation; Half-Life; Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Time Factors | 1983 |
Diagnosis and treatment of epilepsy.
Topics: Automatism; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Ethosuximide; Humans; Muscle Tonus; Phenobarbital; Phenytoin; Primidone; Telemetry; Valproic Acid | 1983 |
The clinical pharmacology of antiepileptic drugs.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Half-Life; Humans; Intestinal Absorption; Kidney; Kidney Diseases; Kinetics; Liver Diseases; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Tissue Distribution; Trimethadione; Valproic Acid | 1984 |
Interactions between anticonvulsants and other commonly prescribed drugs.
Topics: Analgesics; Anti-Infective Agents; Anticoagulants; Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Drug Interactions; Humans; Intestinal Absorption; Kinetics; Phenobarbital; Phenytoin; Primidone; Protein Binding; Psychotropic Drugs; Succinimides; Sulfonamides; Tissue Distribution; Valproic Acid | 1984 |
Clinical pharmacokinetics of antiepileptic drugs in adults.
Topics: Adult; Aging; Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Disease; Ethosuximide; Female; Humans; Kinetics; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva; Valproic Acid | 1980 |
Anticonvulsant drugs in alcohol withdrawal: use of phenytoin, primidone, carbamazepine, valproic acid, and the sedative anticonvulsants.
Topics: Alcoholism; Anticonvulsants; Carbamazepine; Humans; Hypnotics and Sedatives; Phenytoin; Primidone; Status Epilepticus; Substance Withdrawal Syndrome; Valproic Acid | 1981 |
Pharmacological principles in the long-term treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Kinetics; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Succinimides; Valproic Acid | 1981 |
[The post-traumatic epilepsy (author's transl)].
Topics: Brain Concussion; Brain Injuries; Brain Neoplasms; Carbamazepine; Diagnostic Errors; Electroencephalography; Ependymoma; Epilepsy, Post-Traumatic; Humans; Phenobarbital; Phenytoin; Primidone; Skull | 1981 |
Antiepileptic therapeutic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
Drug interactions with valproic acid.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Fatty Acids, Nonesterified; Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Salicylates; Valproic Acid | 1982 |
Seizure disorders.
Topics: Animals; Cat Diseases; Cats; Diagnosis, Differential; Diazepam; Dog Diseases; Dogs; Epilepsy; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Recurrence; Seizures; Succinimides | 1980 |
Clinically significant pharmacokinetic drug interactions with carbamazepine. An update.
Topics: Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Carbamazepine; Drug Interactions; Ethosuximide; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Valproic Acid | 1996 |
Antiepileptic drug review: part 1.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Drug Interactions; Half-Life; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1998 |
Anticonvulsant therapy in small animals.
Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid | 1998 |
Standards of laboratory practice: antiepileptic drug monitoring. National Academy of Clinical Biochemistry.
Topics: Anticonvulsants; Blood Specimen Collection; Carbamazepine; Drug Interactions; Drug Monitoring; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Valproic Acid | 1998 |
Antiepileptic drug hypersensitivity syndrome.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross Reactions; Diagnosis, Differential; Drug Hypersensitivity; Epilepsy; Exanthema; Humans; Incidence; Male; Phenobarbital; Phenytoin; Primidone; Syndrome | 1998 |
Population pharmacokinetics of lamotrigine adjunctive therapy in adults with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Phenytoin; Primidone; Randomized Controlled Trials as Topic; Retrospective Studies; Triazines | 1999 |
[Neurotoxicity of anticonvulsants].
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenytoin; Primidone; Valproic Acid | 1999 |
SEDATIVES, STIMULANTS, AND INTRAOCULAR PRESSURE IN GLAUCOMA.
Topics: Anticonvulsants; Barbiturates; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Glaucoma; Hydantoins; Hypnotics and Sedatives; Intraocular Pressure; Meperidine; Mephenesin; Meprobamate; Methamphetamine; Methylphenidate; Paraldehyde; Pentobarbital; Pharmacology; Phenytoin; Primidone; Promethazine; Reserpine; Tonometry, Ocular; Tranquilizing Agents | 1964 |
Therapeutic monitoring of antiepileptic drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 2007 |
[Medicaments and oral healthcare. Proliferation of the gingiva].
Topics: Anticonvulsants; Carbamazepine; Cell Proliferation; Ethosuximide; Gingiva; Humans; Netherlands; Oral Hygiene; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 2018 |
27 trial(s) available for phenytoin and primidone
| Article | Year |
|---|---|
One drug (phenytoin) in the treatment of epilepsy.
Topics: Adolescent; Adult; Aged; Drug Evaluation; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Placebos; Primidone; Time Factors | 1976 |
Paracetamol disposition in normal subjects and in patients treated with antiepileptic drugs.
Topics: Acetaminophen; Administration, Oral; Adult; Anticonvulsants; Biological Availability; Carbamazepine; Female; Humans; Injections, Intravenous; Male; Phenobarbital; Phenytoin; Primidone | 1979 |
Anticonvulsants in the treatment of aggression.
Topics: Adult; Aggression; Anticonvulsants; Chlordiazepoxide; Chlorpromazine; Drug Therapy, Combination; Epilepsy; Humans; Impulsive Behavior; Male; Mental Disorders; Neurocognitive Disorders; Phenytoin; Primidone; Schizophrenia; Trifluoperazine; Violence | 1975 |
Interaction of phenytoin and primidone.
Topics: Adolescent; Adult; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1975 |
[Clinical and experimental control of optimal therapy in epilepsy].
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Neurocognitive Disorders; Neuropsychological Tests; Phenytoin; Primidone; Substance-Related Disorders; Valproic Acid | 1990 |
Aspects of compliance: taking drugs and keeping clinic appointments.
Topics: Adolescent; Adult; Anticonvulsants; Appointments and Schedules; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Outpatient Clinics, Hospital; Patient Compliance; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1988 |
Results of a nationwide Veterans Administration Cooperative Study comparing the efficacy and toxicity of carbamazepine, phenobarbital, phenytoin, and primidone.
Topics: Adult; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1987 |
Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures.
Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsies, Partial; Epilepsy; Erectile Dysfunction; Female; Follow-Up Studies; Humans; Leukocyte Count; Lupus Vulgaris; Lymphoma; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Psychoses, Substance-Induced | 1985 |
Influence of folic acid on blood-phenytoin levels.
Topics: Adult; Anticonvulsants; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1971 |
Evaluation of albutoin as an antiepileptic drug.
Topics: Adolescent; Adult; Allyl Compounds; Analysis of Variance; Anticonvulsants; Appetite; Biopharmaceutics; Chromatography, Thin Layer; Clinical Trials as Topic; Drug Evaluation; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Female; Humans; Hydantoins; Male; Middle Aged; Nausea; Phenobarbital; Phenytoin; Placebos; Primidone; Spectrophotometry; Statistics as Topic; Thiohydantoins; Time Factors; Vomiting | 1974 |
"Anticonvulsant action" of vitamin D in epileptic patients? A controlled pilot study.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Calcium; Child; Clinical Trials as Topic; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Magnesium; Male; Phenobarbital; Phenytoin; Placebos; Primidone; Vitamin D | 1974 |
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Electroshock; Epilepsy; Ethosuximide; Humans; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Seizures; Trimethadione; Urea | 1969 |
Folate therapy in epilepsy. A controlled study.
Topics: Clinical Trials as Topic; Cognition; Epilepsy; Evaluation Studies as Topic; Folic Acid; Humans; Leucovorin; Personality; Phenobarbital; Phenytoin; Primidone; Psychological Tests | 1973 |
A controlled trial on Ro 5-4023 (clonazepam) in the treatment of psychomotor epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Carbamazepine; Child; Chlorobenzenes; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Fatigue; Female; Humans; Male; Middle Aged; Nitro Compounds; Phenobarbital; Phenytoin; Placebos; Primidone; Time Factors | 1973 |
Cerebrospinal folate levels in epileptics and their response to folate therapy.
Topics: Anticonvulsants; Blood-Brain Barrier; Clinical Trials as Topic; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Tetrahydrofolates; Vitamin B 12 | 1974 |
Incidence of anticonvulsant osteomalacia and effect of vitamin D: controlled therapeutic trial.
Topics: Adult; Aged; Alkaline Phosphatase; Anticonvulsants; Bone and Bones; Calcium; Creatinine; Epilepsy; Female; Humans; Male; Mathematics; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Placebos; Primidone; Radiometry; Vitamin D | 1973 |
Subnormal serum folate due to anticonvulsive therapy. A double-blind study of the effect of folic acid treatment in patients with drug-induced subnormal serum folates.
Topics: Adult; Anticonvulsants; Clinical Trials as Topic; Epilepsy; Erythrocyte Count; Female; Folic Acid; Hematocrit; Hemoglobinometry; Humans; Male; Phenobarbital; Phenytoin; Placebos; Primidone | 1970 |
Relative anticonvulsant potency of primidone; a double blind comparison.
Topics: Clinical Trials as Topic; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1966 |
Oxazepam in the treatment of psychomotor epilepsy.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Male; Oxazepam; Phenytoin; Primidone; Seizures | 1968 |
Single drug therapy for intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Epilepsy, Temporal Lobe; Humans; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1983 |
Historical perspective on the choice of antiepileptic drugs for the treatment of seizures in adults.
Topics: Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Epilepsy; History, 20th Century; Humans; Phenobarbital; Phenytoin; Primidone; Seizures | 1983 |
[Anti-epileptic agents during pregnancy. A prospective study on the course of pregnancy, malformations and child development].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Akathisia, Drug-Induced; Anencephaly; Anticonvulsants; Craniofacial Dysostosis; Epilepsy; Female; Fetal Growth Retardation; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Primidone; Substance Withdrawal Syndrome; Uterine Cervical Incompetence; Valproic Acid | 1983 |
Systematic testing of medical intractability for carbamazepine, phenytoin, and phenobarbital or primidone in monotherapy for patients considered for epilepsy surgery.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Epilepsy; Follow-Up Studies; Humans; Infant; Middle Aged; Patient Selection; Phenobarbital; Phenytoin; Primidone; Quality of Life; Treatment Failure; Treatment Outcome | 1996 |
Antiepileptic drug treatment in pregnancy: drug side effects in the neonate and neurological outcome.
Topics: Anticonvulsants; Child; Drug Monitoring; Epilepsy; Female; Follow-Up Studies; Humans; Nervous System Diseases; Neurologic Examination; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Primidone; Valproic Acid | 1996 |
Outcome evaluation of gabapentin as add-on therapy for partial seizures. "NEON" Study Investigators Group. Neurontin Evaluation of Outcomes in Neurological Practice.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurologic Examination; Phenobarbital; Phenytoin; Primidone; Quality of Life; Valproic Acid | 1998 |
Does withdrawal of different antiepileptic drugs have different effects on seizure recurrence? Further results from the MRC Antiepileptic Drug Withdrawal Study.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Combinations; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Proportional Hazards Models; Recurrence; Risk Assessment; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1999 |
[Evaluation of antiepileptic therapy during pregnancy].
Topics: Adult; Anticonvulsants; Apgar Score; Drug Therapy, Combination; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Primidone; Valproic Acid | 2002 |
531 other study(ies) available for phenytoin and primidone
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
[Adverse effects of anti-epileptic drugs].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Mephenytoin; Nitrazepam; Phenytoin; Primidone; Succinimides; Thiazines; Trimethadione; Valproic Acid | 1975 |
Interactions between anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Humans; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Thiazines | 1975 |
Prognosis and therapy of complex partial seizures with barbiturates, hydantoins, and other drugs.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Prognosis; Succinimides; Thiazines; Valproic Acid | 1975 |
Salivary levels of anticonvulsants: a practical approach to drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Saliva | 1977 |
Simultaneous measurement of phenobarbital, phenytoin, primidone, ethosuximide, and carbamazepine in serum by high-pressure liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Hot Temperature; Humans; Hydrogen-Ion Concentration; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Relative effectiveness of primidone (Mysoline) and diphenylhydantoin (Dilantin) in the management of sedative withdrawal seizures.
Topics: Antipsychotic Agents; Chlordiazepoxide; Drug Evaluation; Humans; Phenothiazines; Phenytoin; Primidone; Seizures; Substance Withdrawal Syndrome | 1976 |
Measurement of anti-epileptic drugs in plasma by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Phenobarbital; Phenytoin; Primidone; Quality Control; Thiazines | 1977 |
The extraction of antiepileptic drugs. Model study on partition coefficients.
Topics: Anticonvulsants; Carbamazepine; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Solvents; Spectrum Analysis | 1978 |
Simple GLC analysis of anticonvulsant drugs in commercial dosage forms.
Topics: Anticonvulsants; Chromatography, Gas; Glutethimide; Hydantoins; Mephenytoin; Phenytoin; Primidone; Succinimides | 1978 |
[The coincidence of visceral lupus erythematosus and epilepsy].
Topics: Adolescent; Carbamazepine; Epilepsy, Tonic-Clonic; Humans; Lupus Erythematosus, Systemic; Male; Phenytoin; Prednisolone; Primidone; Thiazines | 1978 |
Anticonvulsant therapy and serum gamma-glutamyl-transferase.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Kinetics; Male; Middle Aged; Phenytoin; Primidone; Sex Factors; Time Factors | 1978 |
An improved method for preparation of samples for the simultaneous assay of some antiepileptic drugs by gas-liquid chromatography.
Topics: Barbiturates; Body Fluids; Chromatography, Gas; Female; Humans; Milk, Human; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva | 1978 |
[Drug interactions in antiepileptic combination therapy].
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Thiazines; Time Factors; Urea; Valproic Acid | 1979 |
Use of anticonvulsant drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Gas-liquid chromatography of undervatized drugs after chromatographic extraction from blood.
Topics: Amobarbital; Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Chromatography, Gas; Gastric Juice; Glutethimide; Humans; Hypnotics and Sedatives; Methaqualone; Phenobarbital; Phenytoin; Piperidones; Primidone; Secobarbital | 1979 |
Amines, anticonvulsants, and epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Chromatography, Gas; Drug Therapy, Combination; Epilepsy; Fluorometry; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Middle Aged; Phenobarbital; Phenylacetates; Phenytoin; Primidone | 1975 |
Letter: Bioavailability of drugs after intramuscular injection.
Topics: Absorption; Administration, Oral; Adult; Biological Availability; Biotransformation; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Injections, Intramuscular; Male; Phenobarbital; Phenytoin; Primidone | 1975 |
EEG changes after withdrawal of medication in epileptic patients.
Topics: Adult; Anticonvulsants; Brain; Electroencephalography; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome | 1975 |
Interactions of antiepileptic drugs.
Topics: Anti-Infective Agents; Anticonvulsants; Benzodiazepines; Biotransformation; Blood Proteins; Carbamazepine; Dextropropoxyphene; Dicumarol; Disulfiram; Drug Interactions; Ethosuximide; Humans; Intestinal Absorption; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Protein Binding; Thiazines | 1975 |
The effect of phenytoin and ethosuximide on primidone metabolism in patients with epilepsy.
Topics: Drug Interactions; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
How doctors deal with epilepsy.
Topics: Adolescent; Adult; Aged; Automobile Driving; Diazepam; Drug Therapy, Combination; Electroencephalography; Epilepsy; Evaluation Studies as Topic; Follow-Up Studies; Humans; London; Middle Aged; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Referral and Consultation | 1977 |
Therapeutic and pharmacokinetic effects of increasing phenytoin in chronic epileptics on multiple drug therapy.
Topics: Adult; Biological Availability; Chronic Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1976 |
In vivo interaction of anticonvulsant drugs. The mathematical correlation of plasma levels of anticonvulsant drugs in epileptic patients.
Topics: Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone | 1978 |
Haematological effects of anticonvulsant treatment.
Topics: Drug Therapy, Combination; Epilepsy; Erythrocyte Volume; Erythrocytes, Abnormal; Humans; Phenytoin; Primidone | 1978 |
Effects of anticonvulsant drugs on thyroid hormones in epileptic children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Cholesterol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Primidone; Protein Binding; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine; Valproic Acid | 1978 |
Serotonin metabolism with idiopathic grand mal seizures.
Topics: Blood Platelets; Calcium; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Humans; Phenytoin; Primidone; Serotonin | 1978 |
Anticonvulsant drugs and cancer. A cohort study in patients with severe epilepsy.
Topics: Adolescent; Adult; Brain Neoplasms; Child; England; Epilepsy; Female; Follow-Up Studies; Humans; Male; Neoplasms; Phenobarbital; Phenytoin; Primidone; Risk; Sex Ratio; Spinal Cord Neoplasms; Time Factors; Wales | 1979 |
[Clinical significance of serum phenytoin level].
Topics: Adult; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Male; Phenytoin; Primidone | 1978 |
[Blood level of antiepileptic drugs and therapeutic effect in mono- and polytherapy (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1978 |
Pharmacological interactions of mesuximide with phenobarbital and phenytoin in hospitalized epileptic patients.
Topics: Adolescent; Adult; Child; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy, Absence; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Succinimides | 1979 |
Seizure activity and anticonvulsant drug concentration.
Topics: Anticonvulsants; Child; Circadian Rhythm; Diazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroencephalography; Epilepsy; Female; Half-Life; Humans; Male; Phenobarbital; Phenytoin; Primidone; Sleep Stages; Sleep, REM; Telemetry | 1975 |
Patients with epilepsy.
Topics: Affective Symptoms; Age Factors; Alcoholism; Barbiturates; Child; Child, Preschool; Craniocerebral Trauma; Endocrine System Diseases; Epilepsy; Fever; Humans; Hyperventilation; Infant; Patient Compliance; Phenytoin; Photic Stimulation; Primidone; Sleep; Sleep, REM; Succinimides; Water-Electrolyte Imbalance | 1975 |
[Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, Preschool; Clonazepam; Diazepam; Electroencephalography; Epilepsy; Female; Humans; Infant; Male; Nitrazepam; Phenobarbital; Phenytoin; Primidone; Seizures; Spasms, Infantile; Syndrome | 1977 |
Organic nitrogen-selective detector used in gas-chromatographic determination of some anticonvulsant and barbiturate drugs in plasma and tissues.
Topics: Animals; Anticonvulsants; Barbiturates; Brain Chemistry; Carbamazepine; Chromatography, Gas; Horses; Humans; Hydantoins; Methods; Nitrogen; Phenobarbital; Phenytoin; Primidone; Time Factors | 1975 |
A primate model for testing anticonvulsant drugs.
Topics: Allyl Compounds; Animals; Anticonvulsants; Carbamazepine; Chromatography, Gas; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Evaluation, Preclinical; Electroencephalography; Ethosuximide; Female; Glycine; Male; Myoclonus; Papio; Phenobarbital; Phenytoin; Photic Stimulation; Primidone; Seizures; Thiazines | 1975 |
Antiepileptic drugs: biotransformation, metabolism, and serum half-life.
Topics: Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biotransformation; Carbamazepine; Half-Life; Humans; Hydantoins; Oxazoles; Phenylurea Compounds; Phenytoin; Primidone; Succinimides; Sulfonamides | 1975 |
Involuntary movements caused by phenytoin intoxication in epileptic patients.
Topics: Adult; Chlorpheniramine; Diazepam; Drug Interactions; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Movement Disorders; Phenobarbital; Phenytoin; Primidone; Thiazines | 1975 |
[Effects of combination of anti-epileptic drugs].
Topics: Adrenergic beta-Antagonists; Anticonvulsants; Benzodiazepines; Carbamazepine; Digitoxin; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Lithium; Phenobarbital; Phenytoin; Primidone; Thiazines; Tolbutamide; Tranquilizing Agents | 1975 |
Automated computer analysis for enzyme-multiplied immunological techniques.
Topics: Computers; Dose-Response Relationship, Immunologic; Evaluation Studies as Topic; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1977 |
Anticonvulsants in serum, determined with a fully mechanized enzyme analyzer.
Topics: Evaluation Studies as Topic; Glucosephosphate Dehydrogenase; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1977 |
Use of saliva in therapeutic drug monitoring.
Topics: Antipyrine; Caffeine; Ethosuximide; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Saliva; Theophylline | 1977 |
Drug interactions during anticonvulsant therapy in childhood: diphenylhydantoin, primidone, phenobarbitone, clonazepam, nitrazepam, carbamazepin and dipropylacetate.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Nitrazepam; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1977 |
Enzyme immunoassay of phenobarbital phenytoin, and primidone with the ABA-100 bichromatic analyzer.
Topics: Autoanalysis; Humans; Immunoenzyme Techniques; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Determination of phenobarbital and phenytoin in serum by a mechanized enzyme immunoassay (EMIT) in comparison with a gas-liquid chromatographic method.
Topics: Child; Chromatography, Gas; Chromatography, Liquid; Female; Humans; Immunoenzyme Techniques; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
[Plasma levels of anticonvulsants. Experiences with routine plasma level determination of 6 different anticonvulsants].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
Thyroid function tests in patients on long-term treatment with various anticonvulsant drugs.
Topics: Adolescent; Adult; Carbamazepine; Female; Humans; Male; Middle Aged; Phenytoin; Primidone; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine; Valproic Acid | 1978 |
[Ultrastructural changes of murine cerebellum after anticonvulsant administration. I. Acute intoxication (author's transl)].
Topics: Acute Disease; Animals; Anticonvulsants; Cerebellum; Mice; Phenytoin; Primidone; Valproic Acid | 1977 |
Long-term use of the major anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Time Factors; Valproic Acid | 1978 |
[The studies on the antiepileptic drug estimation by means of EMIT-AED (author's transl)].
Topics: Enzyme-Linked Immunosorbent Assay; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Reagent Kits, Diagnostic | 1978 |
Consecutive gas chromatographic determination of phenytoin, phenobarbital, primidone, phenylethylmalondiamide, carbamazepine, trimethadione, dimethadione, ethosuximide, and valproate from the same serum specimen.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Dimethadione; Ethosuximide; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Trimethadione; Valproic Acid | 1978 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Status Epilepticus; Valproic Acid | 1979 |
Recent advances in drug therapy for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Drug Interactions; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Evaluation of automated enzyme immunoassays for five anticonvulsants and theophylline adapted to a centrifugal analyzer.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1979 |
The use of antiepileptic drugs.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
[The serum concentration of anticonvulsants -- pharmacokinetic findings and practical therapeutic applications (author's transl)].
Topics: Antacids; Anticonvulsants; Biological Availability; Carbamazepine; Chromatography, Gas; Clonazepam; Dosage Forms; Ethosuximide; Half-Life; Humans; Immunoenzyme Techniques; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone; Seizures; Valproic Acid | 1979 |
Accuracy of serum anticonvulsant measurements. A comparison of enzyme multiplied immunoassay technique and gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1979 |
High pressure liquid chromatography for simultaneous analysis of anticonvulsants: comparison with EMIT system.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Immunoenzyme Techniques; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Reference Standards | 1979 |
[Changes in the thyroid hormone system with combined anticonvulsion treatment of epileptic children and adolescents (author's transl)].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Cholesterol; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Humans; Iodine; Liver; Phenytoin; Primidone; Protein Binding; Thyroid Gland; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins | 1977 |
Medical treatment of epilepsy: Part II.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Calcium; Child; Drug Interactions; Epilepsy; Epilepsy, Tonic-Clonic; Female; Gingival Hyperplasia; Humans; Hyperkinesis; Phenobarbital; Phenytoin; Pregnancy; Primidone; Status Epilepticus | 1978 |
Epilepsy among parents of children with facial clefts.
Topics: Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Humans; Male; Parents; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone | 1979 |
[Significance of pharmacogenic liver reactions for metabolism of endogenous and exogenous substances].
Topics: Carbamazepine; Diazepam; Drug-Related Side Effects and Adverse Reactions; Female; Fenoterol; Humans; Liver; Phenobarbital; Phenytoin; Pregnancy; Primidone | 1979 |
Serum anticonvulsant monitoring by liquid chromatography with a methanolic mobile phase.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1979 |
Biochemical variables related to calcium metabolism in epileptics.
Topics: Aged; Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Phosphates; Primidone | 1979 |
Mucocutaneous eruptions due to antiepileptic drug therapy in children.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Erythema Multiforme; Female; Humans; Male; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Stevens-Johnson Syndrome | 1979 |
Schizophrenia-like psychosis associated with anticonvulsant toxicity.
Topics: Adult; Anticonvulsants; Athetosis; Carbamazepine; Chorea; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Primidone; Psychoses, Substance-Induced; Schizophrenia | 1979 |
Improved determination of phenobarbital, primidone, and phenytoin by use of a preparative instrument for extraction, followed by gas chromatography.
Topics: Autoanalysis; Chromatography, Gas; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin; Primidone | 1979 |
[Drug therapy of epilepsy with control of the serum level of anti-epileptic agents].
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1979 |
[Difference of serum diphenylhydantoin levels between cases taking diphenylhydantoin alone and cases taking multiple anti-convulsants in various age groups (author's transl)].
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Drug Interactions; Humans; Infant; Phenytoin; Primidone; Regression Analysis | 1979 |
Monitoring saliva anticonvulsant levels in children.
Topics: Anticonvulsants; Carbamazepine; Child; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Saliva | 1979 |
Flashing pain syndrome.
Topics: Animals; Carbamazepine; Pain; Phenytoin; Primidone; Rats; Syndrome | 1977 |
Simultaneous gas chromatographic analysis for the seven commonly used antiepileptic drugs in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1977 |
Therapeutic monitoring of anticonvulsant drugs in psychiatric patients: rapid, simultaneous gas-chromatographic determination of six commonly used anticonvulsants without interference from other drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1978 |
[A study on anticonvulsant level in body fluid. Ist report: serum level and drug interaction (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1977 |
A practical routine gas chromatographic determination of phenobarbital, primidone and diphenylhydantoin.
Topics: Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Spectrophotometry, Ultraviolet | 1978 |
The toxicity of the major anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1978 |
Hypocalcaemia and secondary hyperparathyroidism in institutionalised mentally-retarded patients receiving anticonvulsant drugs: a survey of 292 patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Female; Humans; Hydroxycholecalciferols; Hyperparathyroidism, Secondary; Hypocalcemia; Intellectual Disability; Male; Middle Aged; Osteomalacia; Osteoporosis; Parathyroid Hormone; Phenobarbital; Phenytoin; Primidone; Radiography | 1978 |
[A study on anticonvulsant level in body fluids. 2nd report: Dialyzed serum (free form), CSF and saliva level (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Saliva | 1978 |
Rapid quantitative method for the simultaneous determination of carbamazepine, carbamazepine-10,11-epoxide, diphenylhydantion, mephenytoin, phenobarbital and primidone in serum by thin-layer chromatography.
Topics: Carbamazepine; Chromatography, Thin Layer; Drug Combinations; Epoxy Compounds; Humans; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone | 1978 |
Simultaneous gas chromatographic determination of diphenylhydantoin, carbamazepin (Tegretol), phenobarbital and primidone in presence of Kemadrin (procyclidine) and Prolixin (fluphenazine) in plasma of psychiatric patients.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Fluphenazine; Humans; Mental Disorders; Methods; Phenobarbital; Phenytoin; Primidone; Procyclidine; Pyrrolidines | 1978 |
Simultaneous determination of diphenylhydantoin, mephobarbital, carbamazepine, phenobarbital and primidone in serum using direct chemical ionization mass spectrometry.
Topics: Anticonvulsants; Carbamazepine; Computers; Evaluation Studies as Topic; Humans; Mass Spectrometry; Mephobarbital; Methods; Palmitic Acids; Phenobarbital; Phenytoin; Primidone | 1978 |
Improved gas-chromatographic analysis for anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Reference Standards | 1978 |
Kinetics of drug interactions in the treatment of epilepsy.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethanol; Female; Humans; Kinetics; Male; Phenobarbital; Phenytoin; Pregnancy; Primidone; Salicylates | 1978 |
Rapid micro-method for the measurement of phenobarbitone, primidone and phenytoin in blood plasma or serum by gas-liquid chromatography.
Topics: Animals; Cattle; Chromatography, Gas; Chromatography, Liquid; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone; Time Factors | 1978 |
Brain concentrations of carbamazepine and carbamazepine-10,11-epoxide in epileptic patients.
Topics: Adolescent; Brain; Carbamazepine; Child; Epilepsy; Epoxy Compounds; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1978 |
Downbeat nystagmus due to anticonvulsant toxicity.
Topics: Adult; Anticonvulsants; Carbamazepine; Eye Movements; Female; Humans; Nystagmus, Pathologic; Phenytoin; Primidone | 1978 |
[Problems of mutagenic side effects of psychotropic substances. 1. Psychotropic drugs, narcotics, anticonvulsants].
Topics: Animals; Anticonvulsants; Barbiturates; Chromosome Aberrations; Humans; Hypnotics and Sedatives; Lymphocytes; Mutagens; Phenothiazines; Phenytoin; Primidone; Psychotropic Drugs | 1979 |
[Simultaneous determination of antiepileptic drugs in clinical laboratories: Problems of quality control and standardization (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Evaluation Studies as Topic; Humans; Methods; Phenobarbital; Phenytoin; Primidone; Quality Control | 1979 |
[Measurement of the blood concentration of antiepileptic drugs. II Special cases].
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1975 |
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Male; Phenobarbital; Phenylacetates; Phenytoin; Primidone; Probenecid | 1975 |
Blood level estimation in phenytoin treatment of epilepsy.
Topics: Adult; Child; Chromatography, Gas; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
Seizures in adolescents.
Topics: Adolescent; Anticonvulsants; Automobile Driving; Benzodiazepines; Carbamazepine; Diagnosis, Differential; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Female; Humans; Hysteria; Male; Phenobarbital; Phenytoin; Physical Exertion; Pregnancy; Primidone; Psychology, Adolescent | 1975 |
Isoniazid as an inhibitor of primidone metabolism.
Topics: Depression, Chemical; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Isoniazid; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Pyridoxine; Tuberculosis, Miliary | 1975 |
Sensible prescribing. XI.--Juvenile and adult epilepsy.
Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Clonazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
Effects of different dosages of anticonvulsant drugs on mental performance in patients with chronic epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Child; Chronic Disease; Dose-Response Relationship, Drug; Epilepsies, Partial; Epilepsy; Humans; Intelligence Tests; Memory; Middle Aged; Phenobarbital; Phenytoin; Primidone; Reaction Time | 1975 |
Epilepsy: a controllable disease. Part 2. Drug therapy and nursing care.
Topics: Acute Disease; Adolescent; Anticonvulsants; Child; Epilepsy; Ethosuximide; Gingival Hyperplasia; Humans; Long-Term Care; Phenobarbital; Phenytoin; Primidone | 1976 |
Congenital malformations in four siblings of a mother taking anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anticonvulsants; Child; Child, Preschool; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Pregnancy; Primidone; Trimethadione | 1976 |
Epilepsy and other seizure disorders in children: drug management.
Topics: Acetazolamide; Anticonvulsants; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides; Trimethadione | 1976 |
Immunoglobulin levels and autoantibodies in epileptics on long-term anticonvulsant therapy.
Topics: Adolescent; Adult; Anticonvulsants; Autoantibodies; Epilepsy; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Liver Function Tests; Male; Middle Aged; Muscle, Smooth; Phenytoin; Primidone; Time Factors | 1977 |
Simultaneous determination of phenobarbitone, primidone and phenytoin in small samples of blood by gas-liquid chromatography.
Topics: Chromatography, Gas; Chromatography, Liquid; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Micro-scale anticonvulsant assay with use of nitrogen/phosphorus detector and on-column methylation compared with a macro-scale procedure involving flame-ionization detection.
Topics: Anticonvulsants; Chromatography, Gas; Flame Ionization; Humans; Methylation; Phenobarbital; Phenytoin; Primidone | 1977 |
Quality control in the simultaneous assay of anticonvulsants using an automated gas chromatographic system with a nitrogen detector.
Topics: Anticonvulsants; Chromatography, Gas; Humans; Methylation; Nitrogen; Phenobarbital; Phenytoin; Primidone; Quality Control | 1977 |
Simultaneous determination of anticonvulsant drugs by gas-liquid chromatography.
Topics: Anticonvulsants; Chromatography, Gas; Ethosuximide; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Serum levels of anticonvulsants and haematological sequelae in black epileptics.
Topics: Adolescent; Adult; Aged; Black People; Child; Child, Preschool; Drug Combinations; Epilepsy; Erythrocytes; Female; Folic Acid; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1977 |
Evidence of osteomalacia in an outpatient group of adult epileptics.
Topics: Adult; Aged; Diet; Epilepsy; Female; Humans; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Time Factors | 1977 |
Evaluation of a rapid gas-chromatographic method for the simultaneous quantitative determination of ethosuximide, phenyletheylmalonediamide, carbamazepine, phenobarbital, primidone and diphenylhydantoin in human serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Evaluation Studies as Topic; Humans; Methods; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1977 |
Gas chromatographic on-column methylation technique for the simulataneous determination of antiepileptic drugs in blood.
Topics: Anticonvulsants; Chromatography, Gas; Ethosuximide; Methylation; Phenobarbital; Phenytoin; Primidone | 1977 |
[Determination of the blood levels of phenobarbital, primidone and diphenylhydantoin].
Topics: Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Primidone; Radioimmunoassay | 1977 |
A comparison of the teratogenic activity of the antiepileptic drugs carbamazepine, clonazepam, ethosuximide, phenobarbital, phenytoin, and primidone in mice.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Female; Fetus; Lethal Dose 50; Maternal-Fetal Exchange; Mice; Phenobarbital; Phenytoin; Pregnancy; Primidone; Teratogens | 1977 |
The effect of anticonvulsant drugs which induce liver microsomal enzymes on derived and ingested phenobarbitone levels.
Topics: Adolescent; Adult; Biotransformation; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1977 |
The investigation of phenobarbitone, phenytoin and primidone in the death of epileptics.
Topics: Epilepsy; Forensic Medicine; Humans; Phenobarbital; Phenytoin; Primidone | 1977 |
[The anti-epileptic drugs].
Topics: Age Factors; Anticonvulsants; Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1977 |
N-Acetyltryptophan ethyl ester: a new internal standard for the gas chromatographic determination of plasma anticonvulsant levels.
Topics: Anticonvulsants; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Tryptophan | 1977 |
Distribution of plasma phenobarbital, diphenylhydantoin and primidone levels in epileptic patients.
Topics: Adult; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1977 |
Multiple vitamin deficiencies in association with chronic anticonvulsant therapy.
Topics: Anticonvulsants; Ascorbic Acid Deficiency; Avitaminosis; Beriberi; Child, Preschool; Female; Heart Diseases; Humans; Phenobarbital; Phenytoin; Primidone; Rickets | 1977 |
Comparison of six procedures for the simultaneous determination of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1977 |
Simultaneous high-pressure liquid-chromatographic determination of some anticonvulsants in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1976 |
Monitoring drug concentrations in a case of combined overdosage with primidone and methsuximide.
Topics: Adult; Computers; Female; Gas Chromatography-Mass Spectrometry; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone; Succinimides | 1976 |
Teratogenic effect of anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acetazolamide; Anticonvulsants; Child; Child, Preschool; Diazepam; Female; Humans; Infant; Male; Pedigree; Phenobarbital; Phenytoin; Pregnancy; Primidone | 1976 |
Ascorbic acid concentrations in human plasma and cerebrospinal fluid [proceedings].
Topics: Ascorbic Acid; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1976 |
[Clinical characteristics of psychopathologic changes induced by medicinal anti-epileptic therapy].
Topics: Adolescent; Adult; Anticonvulsants; Barbiturates; Benzodiazepines; Consciousness Disorders; Drug Therapy, Combination; Female; Humans; Male; Mental Disorders; Middle Aged; Movement Disorders; Phenytoin; Primidone; Sleep Wake Disorders | 1976 |
Simultaneous quantitative gas-chromatographic analysis of ethosuximide, phenobarbitone, primidone and diphenylhydantoin.
Topics: Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1976 |
Chemical ionization mass spectrometry for rapid assay of drugs in serum.
Topics: Anticonvulsants; Barbiturates; Caffeine; Carbamazepine; Electrochemistry; Mass Spectrometry; Nicotine; Phenytoin; Primidone; Temperature; Time Factors | 1976 |
Quantitative determination of underivatized anti-convulsant drugs by high resolution gas chromatography with support-coated open tubular columns.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1976 |
Improved method for measurement of serum levels of phenobarbital, carbamazepine, primidone and diphenylhydantoin by gas-liquid chromatography.
Topics: Analysis of Variance; Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Temperature | 1976 |
Simultaneous gas chromatographic analysis for the four commonly used antiepileptic drugs in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ion Exchange Resins; Phenobarbital; Phenytoin; Primidone; Temperature | 1976 |
Anticonvulsant-induced dyskinesias: a comparison with dyskinesias induced by neuroleptics.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cerebellar Diseases; Chorea; Dyskinesia, Drug-Induced; Extremities; Facial Muscles; Female; Humans; Male; Middle Aged; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Syndrome; Tranquilizing Agents; Tremor | 1976 |
[Psychotropic drugs for behavior disorder treatment in oligophrenic epileptics].
Topics: Adult; Epilepsy; Humans; Intellectual Disability; Methotrimeprazine; Phenytoin; Primidone; Promazine; Social Behavior Disorders | 1976 |
The necessity of drug level monitoring in anticonvulsant drug therapy.
Topics: Body Weight; Dose-Response Relationship, Drug; Epilepsy; Humans; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1976 |
Teratogenic activity of the antiepileptic drugs phenobarbital, phenytoin, and primidone in mice.
Topics: Animals; Cleft Palate; Drug Interactions; Female; Gestational Age; Leucovorin; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Pregnancy; Primidone; Teratogens | 1975 |
Letter: Sodium valproate in the treatment of intractable childhood epilepsy.
Topics: Diazepam; Drug Therapy, Combination; Epilepsy; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Valerates; Valproic Acid | 1975 |
Elevation of diphenylhydantoin and primidone serum concentration by addition of dipropylacetate, a new anticonvulsant drug.
Topics: Child; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Primidone; Valerates; Valproic Acid | 1975 |
Surgery of temporal lobe epilepsy.
Topics: Adolescent; Adult; Astrocytes; Brain Neoplasms; Cerebral Cortex; Child; Child, Preschool; Electroencephalography; Epilepsy, Temporal Lobe; Follow-Up Studies; Glioma; Hemiplegia; Humans; Infant; Intellectual Disability; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Socioeconomic Factors; Temporal Lobe | 1975 |
Flash-heater ethylation of some antiepileptic drugs.
Topics: Alkylation; Anticonvulsants; Evaluation Studies as Topic; Hot Temperature; Humans; Mephenytoin; Mephobarbital; Methylation; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
[Investigations of serum levels of drugs in children receiving anticonvulsant medication. I. General evaluation of serum concentrations of diphenylhydantoin, primidone and phenobarbitone (author's transl)].
Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Chromatography, Gas; Drug Therapy, Combination; Humans; Infant; Phenobarbital; Phenytoin; Primidone | 1975 |
[Investigations of serum levels of drugs in children receiving anticonvulsant medication. II. Clinical observations (author's transl)].
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Diazepam; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1975 |
Proceedings: Clinical pharmacokinetics of antiepileptic drugs. Quantitative variables of drug clearance used for the individual assessment of dosage regimens.
Topics: Anticonvulsants; Drug Interactions; Ethosuximide; Humans; Hydroxybutyrates; Phenobarbital; Phenytoin; Primidone | 1974 |
Improved method for the simultaneous determination of phenobarbital, primidone and diphenylhydantoin in patient's serum by gas-liquid chromatography.
Topics: Anticonvulsants; Chromatography, Gas; Drug Stability; Humans; Methods; Methylation; Phenobarbital; Phenytoin; Primidone | 1975 |
Chromosomes and anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cells, Cultured; Chromatids; Chromosome Aberrations; Chromosomes; Ethosuximide; Female; Humans; In Vitro Techniques; Phenytoin; Polyploidy; Pregnancy; Primidone | 1975 |
Anticonvulsant level in saliva, serum, and cerebrospinal fluid.
Topics: Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
Effects and complications of high efficiency dialysis.
Topics: Barbiturates; Blood Urea Nitrogen; Body Weight; Calcium; Creatinine; Edema; Headache; Humans; Hypotension; Kidneys, Artificial; Nausea; Phenobarbital; Phenytoin; Poisoning; Primidone; Renal Dialysis; Salicylates; Substance-Related Disorders; Ultrafiltration; Uremia; Uric Acid | 1975 |
Letter: Gas-chromatography of anticonvulsant drugs, with no solvent evaporation.
Topics: Anticonvulsants; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
Therapeutic monitoring of anticonvulsant drugs: gas-chromatographic simultaneous determination of primidone, phenylethylmalonamide, carbamazepine, and diphenylhydantoin.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Malonates; Microchemistry; Phenylethylmalonamide; Phenytoin; Primidone | 1975 |
Drug interaction: diazoxide and diphenylhydantoin.
Topics: Administration, Oral; Adolescent; Child, Preschool; Chromatography, Gas; Diazoxide; Drug Therapy, Combination; Ethosuximide; Humans; Hyperinsulinism; Hypoglycemia; Infant; Injections, Intramuscular; Male; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Radioligand Assay; Seizures | 1975 |
Cognitive and motor-sensory performances in toxic and nontoxic epileptic subjects.
Topics: Adult; Attention; Cognition; Epilepsy; Female; Humans; Intelligence Tests; Male; Motor Skills; Phenobarbital; Phenytoin; Primidone; Psychological Tests; Sensation | 1975 |
Congenital malformations due to anticonvulsive drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anencephaly; Anticonvulsants; Birth Order; Cleft Lip; Cleft Palate; Epilepsy; Female; Fetal Death; Folic Acid; Folic Acid Antagonists; Hemorrhage; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Trimethadione | 1975 |
Efficacy of standard anticonvulsants in monkey model with spontaneous motor seizures.
Topics: Aluminum; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Feeding Behavior; Humans; Macaca; Male; Motor Cortex; Phenobarbital; Phenytoin; Primidone; Reaction Time; Seizures; Substance Withdrawal Syndrome | 1975 |
[Polarographic determination of some phenylsubstituted anticonvulsants].
Topics: Anticonvulsants; Chromatography, Thin Layer; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Polarography; Primidone | 1975 |
[Nitration products of some phenyl-substituted anticonvulsants].
Topics: Anticonvulsants; Mephenytoin; Nitrogen; Phenobarbital; Phenytoin; Primidone | 1975 |
Kinetic properties of hexokinase in resected temporal lobes of patients with drug-resistant epilepsy.
Topics: Age Factors; Cytoplasm; Epilepsy, Temporal Lobe; Female; Hexokinase; Humans; Kinetics; Male; Phenytoin; Premedication; Primidone; Temporal Lobe | 1975 |
Folate and monoamine metabolism in epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Biogenic Amines; Epilepsy; Erythrocytes; Folic Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Middle Aged; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1975 |
Management of the difficult patient with complex partial seizures.
Topics: Adult; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Female; Humans; Male; Medical Records; Phenytoin; Primidone; Seizures; Social Environment; Substance-Related Disorders | 1975 |
Epilepsy anticonvulsants and malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Heart Defects, Congenital; Humans; Mephobarbital; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Teratogens | 1975 |
Acute primidone overdosage with massive crystalluria.
Topics: Child; Chromatography, Gas; Crystallization; Epilepsy, Temporal Lobe; Female; Humans; Phenobarbital; Phenytoin; Primidone; Time Factors | 1975 |
Diphenylhydantoin, phenobarbital, and primidone in saliva, plasma, and cerebrospinal fluid.
Topics: Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
Brain concentrations of phenytoin, phenobarbitone and primidone in epileptic patients.
Topics: Adolescent; Adult; Brain Chemistry; Child; Child, Preschool; Chromatography, Gas; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
Plasma level studies on different brands of sodium diphenylhydantoin (DPH) and primidone.
Topics: Biological Availability; Capsules; Epilepsy; Female; Humans; Kinetics; Male; Phenobarbital; Phenytoin; Primidone; Solubility; Tablets; Therapeutic Equivalency | 1975 |
Correlation of the "EMIT" antiepileptic drug assay with a gas liquid chromatographic method.
Topics: Autoanalysis; Chromatography, Gas; Humans; Immunoassay; Phenobarbital; Phenytoin; Primidone | 1976 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1976 |
Interlaboratory variability in determination of plasma antiepileptic drug concentrations.
Topics: Anticonvulsants; Epilepsy; Ethosuximide; Humans; Laboratories; Phenobarbital; Phenytoin; Primidone; Quality Control; United States | 1976 |
Simultaneous gas-chromatographic analysis for phenobarbital, diphenylhydantoin, carbamazepine, and primidone in serum.
Topics: Carbamazepine; Chromatography, Gas; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone; Time Factors | 1976 |
Simultaneous measurement of phenobarbital, diphenylhydantoin, and primidone in blood by high-pressure liquid chromatography.
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin; Primidone | 1976 |
Rapid micromethod for measuring anticonvulsant drugs in serum by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Evaluation Studies as Topic; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1976 |
Rapid gas-chromatographic measurement of anticonvulsant drugs in serum.
Topics: Anticonvulsants; Chromatography, Gas; Evaluation Studies as Topic; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone; Time Factors | 1976 |
Ultramicro gas-chromatographic analysis for anticonvulsants, with use of a nitrogen-selective detector.
Topics: Chromatography, Gas; Humans; Microchemistry; Nitrogen; Phenobarbital; Phenytoin; Primidone | 1976 |
Single-dose kinetics of primidone in human subjects: effect of phenytoin on formation and elimination of active metabolites of primidone, phenobarbital and phenylethylmalonamide.
Topics: Adult; Biotransformation; Half-Life; Humans; Male; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1992 |
Performance of fluorescence polarisation immunoassay reagents for carbamazepine, phenytoin, phenobarbitone, primidone, and valproic acid on a Cobas Fara II analyser.
Topics: Anticonvulsants; Carbamazepine; Evaluation Studies as Topic; Fluorescence Polarization Immunoassay; Humans; Phenobarbital; Phenytoin; Primidone; Reference Standards; Valproic Acid | 1991 |
Anticonvulsant therapy increases fentanyl requirements during anaesthesia for craniotomy.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Anticonvulsants; Carbamazepine; Craniotomy; Drug Interactions; Epilepsy; Fentanyl; Humans; Middle Aged; Phenytoin; Primidone; Valproic Acid | 1990 |
Simultaneous determination of six antiepileptic drugs by capillary gas chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Hydroxides; Phenobarbital; Phenytoin; Potassium; Potassium Compounds; Primidone; Valproic Acid | 1990 |
Determination of anticonvulsant drugs and methyl xanthine derivatives in serum by liquid chromatography with direct injection: column-switching method using a new internal-surface reversed-phase silica support as a precolumn.
Topics: Anticonvulsants; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Phenobarbital; Phenytoin; Primidone; Silicon Dioxide; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Xanthines | 1990 |
Development of monoclonal antibodies for therapeutic drug monitoring.
Topics: Antibodies, Monoclonal; Anticonvulsants; Carbamazepine; Cross Reactions; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1990 |
Barbiturate-related connective tissue disorders.
Topics: Adult; Aged; Anticonvulsants; Barbiturates; Carbamazepine; Connective Tissue Diseases; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1989 |
Saliva monitoring of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Saliva | 1989 |
Value of saliva anticonvulsant monitoring in pregnancy and the newborn.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Infant, Newborn; Monitoring, Physiologic; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva | 1989 |
The toxic effects of anticonvulsant drugs in long-term treatment of epilepsy.
Topics: Anticonvulsants; Epilepsy, Temporal Lobe; Female; Humans; Middle Aged; Phenytoin; Primidone | 1989 |
Effects of long-term primidone and phenytoin administration on canine hepatic function and morphology.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Cholesterol; Dogs; Drug Combinations; Female; gamma-Glutamyltransferase; Liver; Microscopy, Electron; Phenytoin; Primidone; Serum Albumin; Time Factors | 1985 |
Rapid and sensitive determination of ethotoin as well as carbamazepine, phenobarbital, phenytoin and primidone in human serum.
Topics: Carbamazepine; Gas Chromatography-Mass Spectrometry; Humans; Hydantoins; Kinetics; Phenobarbital; Phenytoin; Powders; Primidone; Tablets | 1986 |
Factors that affect the induction of gamma glutamyltransferase in epileptic patients receiving anti-convulsant drugs.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Sex Factors | 1987 |
Nursing interventions for anticonvulsant drug interactions.
Topics: Anticonvulsants; Biotransformation; Carbamazepine; Drug Interactions; Humans; Nursing Care; Patient Education as Topic; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1986 |
Carbamazepine, phenytoin and phenobarbital in drug-resistant partial epilepsies.
Topics: Adolescent; Adult; Carbamazepine; Drug Evaluation; Drug Resistance; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1986 |
Phenylethylmalonamide serum levels in patients treated with primidone and the effects of other antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Malonates; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Valproic Acid | 1986 |
Pharmacologic interactions between valproate and other drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1988 |
Relevance of poor compliance for seizure control.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Middle Aged; Patient Compliance; Phenytoin; Primidone; Recurrence; Sleep Deprivation | 1988 |
Fatal paracetamol poisoning in an epileptic.
Topics: Acetaminophen; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Clobazam; Cytochrome P-450 Enzyme System; Drug Interactions; Epilepsy; Humans; Liver; Male; Phenytoin; Primidone | 1988 |
Minor additive inducing effects of phenobarbital on carbamazepine clearance in patients on combined carbamazepine-phenytoin therapy.
Topics: Aged; Carbamazepine; Drug Interactions; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1987 |
Toxic hepatopathy and intrahepatic cholestasis associated with phenytoin administration in combination with other anticonvulsant drugs in three dogs.
Topics: Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Dog Diseases; Dogs; Liver Diseases; Male; Phenobarbital; Phenytoin; Primidone; Seizures | 1987 |
Evaluation of an automated system (Optimate) for substrate-labeled fluorescent immunoassays.
Topics: Anti-Bacterial Agents; Carbamazepine; Evaluation Studies as Topic; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Indicators and Reagents; Methods; Phenobarbital; Phenytoin; Primidone; Quinidine; Theophylline | 1985 |
[Side effects of anticonvulsants on the peripheral nervous system and vestibulo-ocular functions].
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Eye Movements; Female; Humans; Neural Conduction; Peripheral Nerves; Phenytoin; Primidone; Reflex, Stretch; Sensation; Vestibular Nuclei | 1985 |
Effects of pregnancy on antiepileptic drug utilization.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Epilepsy; Female; Humans; Kinetics; Metabolic Clearance Rate; Patient Compliance; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Valproic Acid | 1985 |
Concurrent determination of valproic acid with other antiepileptic drugs by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1985 |
Monotherapy and polytherapy for intractable epilepsies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1985 |
Influence of anticonvulsant drugs on thyroid hormones in epileptic children.
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Humans; Mephenytoin; Phenytoin; Primidone; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1985 |
Alternative single anticonvulsant drug therapy for refractory epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Chronic Disease; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1986 |
[Bioavailabilities of three different phenytoin powders sold in Japan].
Topics: Adolescent; Biological Availability; Carbamazepine; Child; Child, Preschool; Humans; Japan; Phenytoin; Powders; Primidone | 1985 |
Carbamazepine and carbamazepine-10,11-epoxide serum concentrations in epileptic children.
Topics: Adolescent; Age Factors; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Kinetics; Male; Phenobarbital; Phenytoin; Primidone; Sex Factors | 1985 |
Toxic epidermal necrolysis due to antiepileptic therapy in an 8-year-old boy.
Topics: Adult; Anticonvulsants; Child; Diagnosis, Differential; Humans; Infant; Male; Phenytoin; Primidone; Skin; Stevens-Johnson Syndrome | 1985 |
Comparative evaluation of the Optimate and TDX analyzers using NCCLS guidelines.
Topics: Autoanalysis; Carbamazepine; Humans; Phenytoin; Primidone; Specimen Handling; Theophylline; Tobramycin | 1985 |
Congenital malformations among infants born to epileptic women.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Congenital Abnormalities; England; Epilepsy; Female; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone | 1973 |
Coarse features in epilepsy as a consequence of anticonvulsant therapy. Report of cases in two pairs of identical twins.
Topics: Acromegaly; Adult; Anticonvulsants; Carbamazepine; Child; Diazepam; Diseases in Twins; Epilepsy; Epilepsy, Tonic-Clonic; Ethosuximide; Face; Female; Haloperidol; Humans; Hydantoins; Male; Phenobarbital; Phenytoin; Primidone; Thiazines | 1973 |
Are anticonvulsants oncogenic?
Topics: Anticonvulsants; Denmark; Epilepsy; Female; Humans; Male; Neoplasms; Phenobarbital; Phenytoin; Primidone; Sex Factors; Time Factors | 1974 |
[Calcium metabolism during antiepileptic therapy].
Topics: Adult; Alkaline Phosphatase; Anticonvulsants; Antipsychotic Agents; Calcium; Calcium Isotopes; Creatinine; Diazepam; Drug Combinations; Epilepsy; Ethosuximide; Female; Humans; Long-Term Care; Male; Phenobarbital; Phenothiazines; Phenytoin; Piperazines; Primidone; Time Factors | 1973 |
[Frequency of rickets-like bone lesions during anticonvulsive therapy].
Topics: Adolescent; Anticonvulsants; Barbiturates; Bone Development; Carpal Bones; Child; Child, Preschool; Enzyme Induction; Epilepsy; Female; Humans; Male; Osteogenesis; Phenytoin; Primidone; Radiography; Rickets; Thiazines; Time Factors; Vitamin D | 1973 |
Specific H-bonding of glutarimides and hydantoins to derivatives of RNA bases in chloroform solution.
Topics: Bemegride; Chemical Phenomena; Chemistry; Chloroform; Cycloheximide; Ethosuximide; Glutethimide; Hydantoins; Pemoline; Phenobarbital; Phenytoin; Piperidines; Piperidones; Primidone; RNA; Spectrophotometry, Infrared; Thalidomide | 1973 |
Clonazepam (Ro 5-4023) in the treatment of myoclonus epilepsy. Four case reports.
Topics: Adult; Anticonvulsants; Benzodiazepinones; Chlorobenzenes; Diazepam; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Epilepsy; Fatigue; Female; Genetic Diseases, Inborn; Humans; Myoclonus; Nitro Compounds; Phenytoin; Primidone; Thiazines | 1973 |
Choreo-athetosis and encephalopathy induced by phenytoin.
Topics: Adolescent; Adult; Ataxia; Athetosis; Carbamazepine; Chorea; Diplopia; Electroencephalography; Epilepsy; Humans; Intelligence; Male; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Thiazines | 1974 |
Prevalence and treatment of vitamin D deficiency in children on anticonvulsant drugs.
Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Calcium; Cholecalciferol; Diet; Enzyme Induction; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Leucyl Aminopeptidase; Liver; Male; Nucleotidases; Phenobarbital; Phenytoin; Phosphates; Primidone; Radiography; Vitamin D Deficiency; Wrist | 1974 |
Assessment of plasma glutamyl transpeptidase activity and urinary D-glucaric acid excretion as indices of enzyme induction.
Topics: Adipates; Anticonvulsants; Child; Child, Preschool; Enzyme Induction; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Kinetics; Liver Function Tests; Male; Phenobarbital; Phenytoin; Primidone; Sugar Acids | 1974 |
Epilepsy.
Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant, Newborn; Liver; Nitrazepam; Phenobarbital; Phenytoin; Prednisolone; Primidone; Spasm; Syndrome; Thiazines | 1974 |
Gastrointestinal function in anticonvulsant megaloblastic anaemia.
Topics: Adult; Anemia, Macrocytic; Epilepsy; Female; Folic Acid; Humans; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1966 |
Effects of folic acid on the mental state and fit-frequency of drug-treated epileptic patients.
Topics: Adolescent; Adult; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Humans; Male; Mental Health; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1967 |
Neuropsychiatric aspects of anticonvulsant megaloblastic anaemia.
Topics: Acetazolamide; Adult; Anemia, Macrocytic; Epilepsy; Female; Folic Acid; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Psychophysiologic Disorders; Thiazines; Vitamin B 12 | 1968 |
Cerebellar atrophy in epilepsy. Pneumographic and histological documentation of a case with psychosis.
Topics: Adult; Brain; Cerebellar Ataxia; Cerebral Ventriculography; Chlorpromazine; Diplopia; Electroconvulsive Therapy; Electroencephalography; Epilepsy, Tonic-Clonic; Facial Muscles; Female; Gait; Humans; Hydantoins; Intellectual Disability; Neurocognitive Disorders; Nystagmus, Pathologic; Phenytoin; Primidone; Psychological Tests; Purkinje Cells; Schizophrenia; Staining and Labeling | 1968 |
Neonatal haemorrhage following maternal anticonvulsant therapy.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Vitamin K; Vitamin K Deficiency Bleeding | 1970 |
Connective tissue disease following anti-epileptic therapy.
Topics: Adult; Anticonvulsants; Child; Collagen Diseases; Electroencephalography; Epilepsy, Absence; Epilepsy, Temporal Lobe; Female; Humans; Latex Fixation Tests; Neutrophils; Oxazepam; Phenytoin; Prednisolone; Primidone | 1969 |
[Distinct rickets during anticonvulsant long-term therapy].
Topics: Child, Preschool; Enzyme Induction; Epilepsy, Tonic-Clonic; Female; Humans; Phenobarbital; Phenytoin; Primidone; Radiography; Rickets; Vitamin D | 1973 |
The effect of anticonvulsant therapy upon the absorption of folates.
Topics: Adult; Aged; Anticonvulsants; Biological Assay; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Absorption; Lacticaseibacillus casei; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1973 |
[Inheritance of spike-wave complexes and febrile seizures in three generations].
Topics: Adult; Child; Child, Preschool; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Fever; Genes, Dominant; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Time Factors | 1973 |
Antiepileptic therapy and rickets in children.
Topics: Adolescent; Anticonvulsants; Barbiturates; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Male; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Rickets | 1973 |
The pattern of epilepsy in Uganda.
Topics: Adolescent; Adult; Age Factors; Black People; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Folklore; Humans; Male; Phenobarbital; Phenytoin; Primidone; Sex Factors; Socioeconomic Factors; Time Factors; Uganda | 1973 |
Folate studies in underprivileged children with epilepsy.
Topics: Anticonvulsants; Biological Assay; Child; Child, Preschool; Epilepsy; Euglena; Folic Acid; Hematocrit; Hemoglobins; Humans; Lacticaseibacillus casei; Leukocyte Count; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1973 |
Psychomotor epilepsy in childhood.
Topics: Bromides; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Infant; Phenobarbital; Phenytoin; Primidone; Radiography; Recurrence; Skull; Time Factors | 1974 |
[Haemorrhagic diathesis in a newborn child of a mother on anti-epileptic medication (author's transl)].
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Female; Hemostatics; Humans; Infant, Newborn; Maternal-Fetal Exchange; Mephobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Shock, Hemorrhagic; Vitamin K Deficiency Bleeding | 1974 |
Clonazepam in the treatment of epilepsy.
Topics: Adult; Anticonvulsants; Benzodiazepinones; Chlorobenzenes; Chromatography, Gas; Drug Interactions; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Myoclonus; Nitro Compounds; Phenytoin; Primidone | 1974 |
Therapy of seizures in children.
Topics: Child; Diazepam; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Injections, Intramuscular; Injections, Intravenous; Paraldehyde; Phenobarbital; Phenytoin; Primidone; Rectum; Seizures | 1974 |
Prolonged trance-like stupor in epilepsy. Petit mal status-wave stupor, spaced-out status.
Topics: Adult; Behavior; Diagnosis, Differential; Diazepam; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Humans; Intelligence; Male; Middle Aged; Phenytoin; Primidone; Trimethadione; Unconsciousness | 1974 |
[Letter: Ovulation inhibitors during anticonvulsive therapy?].
Topics: Adult; Anticonvulsants; Contraceptives, Oral; Drug Interactions; Epilepsy; Female; Humans; Long-Term Care; Phenytoin; Primidone | 1974 |
[Therapy in traumatic epilepsy].
Topics: Adult; Barbiturates; Bromides; Carbamazepine; Coma; Disabled Persons; Drug Resistance; Epilepsy, Post-Traumatic; Female; Follow-Up Studies; Humans; Male; Phenytoin; Primidone | 1971 |
Clinical and experimental studies on folic acid deficiency due to anticonvulsants. 2. Investigations on patients receiving anticonvulsants and experimental study on the effect of diphenylhydantoin on the absorption of folic acid in rats.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Cell Nucleus; Depression, Chemical; Epithelial Cells; Female; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Absorption; Intestine, Small; Iron; Kidney; Leukocyte Count; Liver; Male; Middle Aged; Mouth Mucosa; Neutrophils; Phenobarbital; Phenytoin; Primidone; Rats; Tritium; Vitamin B 12 | 1971 |
Drug treatment of convulsive disorders.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Adult; Anticonvulsants; Barbiturates; Child; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Myoclonus; Oxazoles; Phenobarbital; Phenytoin; Primidone; Pyrrolidinones; Seizures; Trimethadione | 1972 |
[Severe rachitic osteopathy during long-term anticonvulsant treatment].
Topics: Administration, Oral; Alkaline Phosphatase; Anticonvulsants; Biopsy; Calcium; Carbamazepine; Child; Cholecalciferol; Epilepsy, Tonic-Clonic; Humans; Ilium; Iron; Long-Term Care; Male; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone; Rickets | 1973 |
Peripheral nerve function in long-term therapy with diphenylhydantoin. A clinical and electrophysiologic correlation.
Topics: Adult; Aged; Carbamazepine; Electric Stimulation; Electromyography; Epilepsy; Ethosuximide; Evoked Potentials; Female; Folic Acid; Humans; Male; Median Nerve; Middle Aged; Neural Conduction; Peripheral Nerves; Peripheral Nervous System Diseases; Peroneal Nerve; Phenobarbital; Phenytoin; Primidone; Reaction Time; Reflex, Monosynaptic; Sural Nerve; Time Factors; Vitamin B 12 | 1974 |
Clinical experience with sulthiame (Ospolot).
Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Epilepsy, Temporal Lobe; Female; Humans; Intellectual Disability; Male; Mental Disorders; Middle Aged; Phenobarbital; Phenytoin; Primidone; Thiazines | 1966 |
Motor convulsions and EEG during maximal electroshock in the rat.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Cornea; Electric Stimulation; Electroencephalography; Electroshock; Muscles; Phenobarbital; Phenytoin; Primidone; Rats; Seizures; Stress, Physiological; Succinimides; Thiazines; Trimethadione | 1967 |
Increased susceptibility of mice to seizures after some anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Bemegride; Central Nervous System Stimulants; Drug Synergism; Electroshock; Ethionine; Female; Hydantoins; Male; Methods; Mice; Oxazines; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Rats; Seizures; Trimethadione | 1967 |
Drugs in management of hyperkinetic and perceptually handicapped children.
Topics: Anticonvulsants; Central Nervous System Stimulants; Child; Child, Preschool; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Epilepsy; Humans; Hyperkinesis; Methylphenidate; Perceptual Disorders; Phenytoin; Primidone; Psychological Tests; Seizures; Tranquilizing Agents | 1968 |
Epilepsy.
Topics: Adult; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Folic Acid Deficiency; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Primidone; Psychoses, Substance-Induced; Thiazines | 1969 |
Drug treatment of epilepsy in childhood.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Paraldehyde; Phenobarbital; Phenytoin; Primidone; Thiazines | 1969 |
Interference of barbiturates with pyrimidine incorporation. II. Structural specificity of the inhibition of orotate uptake in Bacillus cereus.
Topics: Amobarbital; Bacillus cereus; Barbiturates; Bemegride; Biological Transport; Carbon Isotopes; Carboxylic Acids; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Chlorpromazine; Glutethimide; Hexobarbital; Hydantoins; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Orotic Acid; Pentobarbital; Phenobarbital; Phenytoin; Primidone; Solubility; Succinimides; Thiopental; Thymine; Trimethadione; Tromethamine; Uracil; Urea | 1970 |
Anticonvulsant drugs in idiopathic epilepsy.
Topics: Acetazolamide; Anticonvulsants; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Hydantoins; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome; Succinimides; Urea | 1970 |
A comprehensive scheme for the evaluation of anticonvulsant concentrations in blood using thin-layer chromatography.
Topics: Acetazolamide; Anticonvulsants; Benzazepines; Carbamazepine; Chlordiazepoxide; Chromatography, Thin Layer; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Nitro Compounds; Oxazepam; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines | 1971 |
Anticonvulsant drugs. I. Patho-physiological and pharmacological aspects.
Topics: Acetates; Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Dibenzazepines; Electroencephalography; Epilepsies, Partial; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Succinimides; Thiazines; Trimethadione | 1972 |
The influence of anticonvulsant drugs on formyl tetrahydrofolic acid stimulation of rat brain respiration in vitro.
Topics: Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; In Vitro Techniques; Leucovorin; Male; Microsomes; Norepinephrine; Oxygen Consumption; Phenobarbital; Phenytoin; Primidone; Rats; Scopolamine; Synaptosomes; Thiazines | 1972 |
[Micro-method for the quantitative determination of sedatives and antipyretics (aminophenazone, diphenylhydantoin, paracetamol, phenobarbital, primidone) using thermo-gas chromatography].
Topics: Acetaminophen; Aminopyrine; Analgesics; Chromatography, Gas; Hypnotics and Sedatives; Methods; Microchemistry; Phenobarbital; Phenytoin; Primidone; Temperature | 1974 |
An evaluation of a drug administration system in a psychiatric hospital.
Topics: Acetaminophen; Antidepressive Agents; Benzodiazepinones; Hospitals, Psychiatric; Humans; Medication Errors; Medication Systems, Hospital; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Salicylates; Scotland | 1974 |
Letter: Sleep epilepsy.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Delayed-Action Preparations; Dextroamphetamine; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Sleep Wake Disorders | 1974 |
Letter: Anticonvulsants and vitamin D metabolism.
Topics: Child; Drug Therapy, Combination; Epilepsy; Humans; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Rickets | 1974 |
Serum immunoglobulins in epilepsy.
Topics: Adult; Drug Therapy, Combination; Epilepsy; Erythrocytes; Female; Folic Acid; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Male; Phenobarbital; Phenytoin; Primidone | 1974 |
Simultaneous determination of some antiepileptic drugs by gas-liquid chromatography.
Topics: Analysis of Variance; Carbamazepine; Chromatography, Gas; Colorimetry; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin; Primidone; Spectrophotometry | 1974 |
Do anticonvulsants have a teratogenic effect?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Child, Preschool; Cleft Lip; Cleft Palate; Congenital Abnormalities; Epilepsy; Female; Heart Defects, Congenital; Humans; Infant; Infant Mortality; Infant, Newborn; Intellectual Disability; Male; Mephobarbital; Minnesota; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Primidone; Teratogens | 1974 |
Broad-spectrum simultaneous GLC assay of nonderivatized antiepileptic drugs.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Trimethadione | 1974 |
[Considerations and research on febrile convulsions].
Topics: Anticonvulsants; Brain Diseases; Child, Preschool; Diagnosis, Differential; Diazepam; Electroencephalography; Epilepsy; Female; Fever; Humans; Infant; Male; Mannitol; Phenobarbital; Phenytoin; Primidone; Seizures | 1974 |
[Special viewpoints in the treatment with anticonvulsants in childhood. Value of determination of serum level of anticonvulsants in the treatment of seizures].
Topics: Adolescent; Anticonvulsants; Child, Preschool; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1974 |
Iatrogenic nutritional effects of anticonvulsants.
Topics: Adolescent; Adult; Anticonvulsants; Blood Coagulation Disorders; Bone Diseases; Child; Child, Preschool; Connective Tissue; Endocrine Glands; Enzyme Induction; Epilepsy; Female; Folic Acid Deficiency; Humans; Iatrogenic Disease; Infant; Infant, Newborn; Liver; Nutrition Disorders; Phenobarbital; Phenytoin; Pregnancy; Primidone; Pyridoxine; Vitamin D Deficiency | 1974 |
Phenobarbital-induced coagulation defects in cats.
Topics: Alanine Transaminase; Animals; Animals, Newborn; Blood Coagulation; Blood Coagulation Disorders; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Factor V Deficiency; Factor VII; Factor VII Deficiency; Female; Folic Acid; Hemophilia A; Hypoprothrombinemias; Liver; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Primidone; Rats; Vitamin K | 1974 |
Effects of age, sex, obesity, and pregnancy on plasma diphenylhydantoin levels.
Topics: Adolescent; Adult; Age Factors; Analysis of Variance; Chromatography, Gas; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Kinetics; Male; Middle Aged; Obesity; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Regression Analysis; Sex Factors; Spectrophotometry | 1974 |
A clinical trial with clonazepam (Ro 5-4023).
Topics: Adolescent; Adult; Anticonvulsants; Barbiturates; Benzodiazepinones; Carbamazepine; Child; Chlorobenzenes; Drug Evaluation; Drug Therapy, Combination; Epilepsy; Fatigue; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitro Compounds; Phenytoin; Primidone; Time Factors; Vertigo | 1973 |
The origin of infantile spasms: evidence from a case of hydranencephaly.
Topics: Anencephaly; Cerebral Ventriculography; Electroencephalography; Electromyography; Female; Humans; Hydranencephaly; Infant; Infant, Newborn; Infant, Newborn, Diseases; Muscle Spasticity; Phenytoin; Primidone | 1972 |
A medical and social survey of 231 children with seizures.
Topics: Adolescent; Attitude to Health; Child; Child Behavior Disorders; Child, Preschool; Electroencephalography; Employment; Encephalitis; Epilepsy; Epilepsy, Absence; Ethosuximide; Female; Greece; Humans; Infant; Intelligence; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Seizures; Socioeconomic Factors | 1972 |
Variation in response to anticonvulsants in a group of epileptic patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Chromatography, Gas; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Sex Factors | 1972 |
Megaloblastic anemia after anticonvulsive therapy.
Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Epilepsies, Partial; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1972 |
Haptoglobin phenotype frequencies in mentally retarded persons.
Topics: Acid Phosphatase; Adenine Nucleotides; Adenosine; Alanine Transaminase; Aminohydrolases; Blood Protein Electrophoresis; Blood Proteins; Electrophoresis, Starch Gel; Female; Haptoglobins; Humans; Immunodiffusion; Intellectual Disability; Isoenzymes; L-Lactate Dehydrogenase; Liver Function Tests; Male; Phenotype; Phenytoin; Phosphoglucomutase; Phosphogluconate Dehydrogenase; Phosphotransferases; Primidone | 1972 |
Long term anticonvulsant therapy and cerebellar atrophy.
Topics: Adult; Avitaminosis; Cerebellar Diseases; Cranial Fossa, Posterior; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Humans; Phenobarbital; Phenytoin; Pneumoencephalography; Primidone | 1973 |
[Osteomalacia due to a long-term antiepileptic treatment].
Topics: Anticonvulsants; Calcium; Female; Humans; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Time Factors; Vitamin D | 1972 |
Clinical conference: megaloblastic anemia associated with anticonvulsant drugs.
Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Female; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone | 1972 |
Relationships between serum and cerebrospinal fluid anticonvulsant drug and folic acid concentrations in epileptic patients.
Topics: Adult; Chromatography, Gas; Epilepsy; Female; Folic Acid; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1972 |
The simultaneous determination of multiple anticonvulsant drug levels by gas-liquid chromatography. Method and clinical application.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Chromatography, Gas; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Methods; Methylphenidate; Phenobarbital; Phenytoin; Primidone | 1972 |
Clinical and physiological effects of stimulation of the paleocerebellum in humans.
Topics: Adult; Cerebellum; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Humans; Male; Muscle Tonus; Muscular Diseases; Phenytoin; Primidone; Seizures | 1973 |
A gas-chromatographic method for the simultaneous determination of phenobarbitone, primidone and phenytoin in serum using a nitrogen detector.
Topics: Chromatography, Gas; Electrodes; Humans; Indicators and Reagents; Methods; Methylation; Nitrogen; Phenobarbital; Phenytoin; Primidone | 1973 |
Follow-up of epileptic outpatients.
Topics: Adolescent; Adult; Aged; Educational Status; Employment; Epilepsy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Rehabilitation, Vocational; Surveys and Questionnaires | 1973 |
Leucine aminopeptidase isoenzyme changes after treatment with anticonvulsant drugs.
Topics: Blood Protein Electrophoresis; Blood Proteins; Epilepsy; Humans; Isoenzymes; Jaundice; Leucyl Aminopeptidase; Phenobarbital; Phenytoin; Primidone | 1973 |
Simultaneous determination of carbamazapine ("Tegretol") and other anticonvulsants in human plasma by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Computers; Dibenzazepines; Humans; Hydantoins; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Quaternary Ammonium Compounds | 1973 |
GC assay of phenobarbital.
Topics: Amides; Benzene Derivatives; Chromatography, Gas; Humans; Malonates; Phenobarbital; Phenytoin; Primidone; Quaternary Ammonium Compounds | 1973 |
Effect of cannabidiol and of other cannabis sativa compounds on hippocampal seizure discharges.
Topics: Animals; Cannabis; Electric Stimulation; Electrodes, Implanted; Hippocampus; Injections, Intraperitoneal; Phenytoin; Phytotherapy; Potassium; Primidone; Rats; Seizures | 1973 |
Chronic and severe phenobarbital intoxication in a child treated with primidone and diphenylhydantoin.
Topics: Anticonvulsants; Biotransformation; Chromatography, Gas; Drug Interactions; Female; Humans; Infant; Infant, Newborn; Phenobarbital; Phenytoin; Primidone; Seizures | 1973 |
[Ambulatory extended care for the child with seizures].
Topics: Adolescent; Age Factors; Ambulatory Care; Child; Child, Preschool; Diazepam; Epilepsy; Ethosuximide; Humans; Infant; Phenytoin; Primidone; Skilled Nursing Facilities | 1973 |
[Severe osteomalacic rickets induced by antiepileptic drugs. Literature review apropos of a case].
Topics: Child; Child, Preschool; Humans; Male; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Rickets; Vitamin D | 1973 |
Vitamin D-dependent rickets in institutionalized, mentally retarded children receiving long-term anticonvulsant therapy. I. A survey of 288 patients.
Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Calcium; Child; Child, Preschool; Female; Humans; Infant; Intellectual Disability; Magnesium; Male; Mephobarbital; Mesoridazine; Phenobarbital; Phenytoin; Phosphorus; Potassium; Primidone; Rickets; Seizures; Sodium; Succinimides; Vitamin D | 1973 |
Pheneturide, a more potent liver enzyme inducer in man than phenobarbitone?
Topics: Adipates; Anticonvulsants; Enzyme Induction; Epilepsy; Female; Humans; Liver; Male; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Sugar Acids; Urea | 1973 |
Primidone, diphenylhydantoin and phenobarbital. Aspects of acute and chronic toxicity.
Topics: Ataxia; Chromatography, Gas; Drug Tolerance; Epilepsy; Humans; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone | 1973 |
Preliminary observations of serum carbamazepine concentration in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1973 |
The role of antiepileptic blood levels in the treatment of patients with epilepsy.
Topics: Adult; Drug Therapy, Combination; Epilepsy; Female; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1973 |
Metabolism of N,2-dimethyl-2-phenylsuccinimide (methsuximide) by the epoxide-diol pathway in rat, guinea pig and human.
Topics: Animals; Anticonvulsants; Child, Preschool; Chromatography, Gas; Ethers, Cyclic; Glucuronates; Guinea Pigs; Humans; Hydroxylation; Male; Mass Spectrometry; Methylation; Phenytoin; Primidone; Rats; Species Specificity; Succinimides | 1973 |
[Development inhibition in brain-damaged children due to anticonvulsants].
Topics: Anticonvulsants; Carbamazepine; Child; Child Development; Electroencephalography; Humans; Intellectual Disability; Intelligence Tests; Phenytoin; Primidone | 1973 |
[Editorial: Antiepileptic agents--folic acid].
Topics: Anemia, Macrocytic; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1973 |
Rapid, simultaneous GLC determination of phenobarbital, primidone, and diphenylhydantoin.
Topics: Chromatography, Gas; Methods; Phenobarbital; Phenytoin; Primidone; Time Factors | 1973 |
A rapid method for the estimation of anti-epileptic drugs in blood serum by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Epilepsy; Ethosuximide; Evaluation Studies as Topic; Humans; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Succinimides; Temperature; Time Factors; Trimethadione | 1973 |
The teratological effects of anticonvulsants and the effects on pregnancy and birth.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cleft Lip; Cleft Palate; Cyclohexanes; Epilepsy; Ethosuximide; Female; Humans; Hydantoins; Male; Mutation; Obstetric Labor Complications; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Propylamines | 1973 |
Minor epileptic status with contractures.
Topics: Child; Contracture; Electroencephalography; Epilepsy; Female; Humans; Intelligence; Phenytoin; Prednisone; Primidone | 1973 |
[Complications of medical therapy for epilepsy in children and adolescents].
Topics: Anticonvulsants; Child; Diplopia; Drug Hypersensitivity; Drug Therapy, Combination; Epilepsy; Headache; Humans; Mental Disorders; Movement Disorders; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Speech Disorders; Vertigo | 1973 |
[Antimetabolites of folic acid metabolism with chemotherapeutic activity against rodent malaria (Plasmodium vinckei)].
Topics: Aminopterin; Animals; Cycloheximide; Female; Folic Acid; Folic Acid Antagonists; Hydantoins; Malaria; Male; Methotrexate; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Plasmodium; Primidone; Pyrimethamine; Thalidomide; Triamterene | 1973 |
The influence of diphenylhydantoin on primidone metabolism.
Topics: Drug Interactions; Enzyme Induction; Female; Humans; Liver; Male; Phenobarbital; Phenytoin; Primidone | 1973 |
Clonazepam in the treatment of epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Chlorobenzenes; Chromatography, Gas; Drug Interactions; Epilepsy; Female; Follow-Up Studies; Humans; Male; Myoclonus; Nitro Compounds; Phenytoin; Primidone | 1973 |
A rapid micro-method for determining four anti-convulsant drugs by gas-liquid chromatography.
Topics: Animals; Anticonvulsants; Carbon Radioisotopes; Chromatography, Gas; Evaluation Studies as Topic; Horses; Methods; Microchemistry; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Time Factors; Urea | 1973 |
Rickets associated with anticonvulsant medication.
Topics: Alkaline Phosphatase; Calcium; Child, Preschool; Female; Humans; Phenobarbital; Phenytoin; Phosphorus; Primidone; Rickets; Seizures; Vitamin D | 1974 |
The influence of diphenylhydantoin on primidone metabolism.
Topics: Adult; Biotransformation; Chromatography, Gas; Drug Interactions; Enzyme Induction; Epilepsy; Female; Humans; Hydroxylation; Liver; Male; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Regression Analysis | 1974 |
Folate metabolism and anticonvulsant therapy.
Topics: Anticonvulsants; Blood-Brain Barrier; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1974 |
Infants exposed in utero to antiepileptic drugs. A prospective study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amitriptyline; Amniotic Fluid; Anticonvulsants; Chromatography, Gas; Diazepam; Epilepsy; Ethosuximide; Female; Fetus; Growth Disorders; Humans; Hydantoins; Infant, Newborn; Mass Spectrometry; Mephobarbital; Meprobamate; Milk, Human; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Prochlorperazine; Prospective Studies; Substance Withdrawal Syndrome; Succinimides; Time Factors | 1974 |
Letter: GLC microdetermination of plasma anticonvulsant levels.
Topics: Anticonvulsants; Chromatography, Gas; Ethosuximide; Humans; Methods; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1974 |
Pharmacology for the pediatrician. Noncompliance contributing to apparent drug failure in status epilepticus.
Topics: Anticonvulsants; Benzodiazepinones; Child; Chlorobenzenes; Diazepam; Epilepsy; Ethosuximide; Female; Humans; Medical Records; Medication Errors; Nitro Compounds; Phenobarbital; Phenytoin; Primidone | 1974 |
Antiepileptic drugs: a current assessment of simultaneous determination of multiple drug therapy by gas liquid chromatography-on column methylation.
Topics: Adult; Anticonvulsants; Autoanalysis; Barbiturates; Buffers; Child; Chromatography, Gas; Humans; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Solvents; Temperature | 1974 |
Decrease in serum diphenylhydantoin levels after withdrawal of phenobarbital in epileptics treated with both drugs.
Topics: Child; Child, Preschool; Chromatography, Gas; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1974 |
Serum levels of diphenylhydantoin and phenobarbital in epileptic children receiving diphenylhydantoin, phenobarbital and-or mysoline.
Topics: Adolescent; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Primidone | 1974 |
Serum anticonvulsant concentrations in epileptic patients with mental symptoms. A preliminary report.
Topics: Adolescent; Adult; Aged; Epilepsy; Female; Humans; Intelligence; Male; Mental Disorders; Middle Aged; Personality Disorders; Phenobarbital; Phenytoin; Primidone; Psychomotor Disorders | 1974 |
Human brain, cerebrospinal fluid, and plasma concentrations of diphenylhydantoin and phenobarbital.
Topics: Adolescent; Adult; Brain Chemistry; Child, Preschool; Chromatography, Gas; Epilepsy, Temporal Lobe; Female; Humans; Male; Nerve Tissue Proteins; Phenobarbital; Phenytoin; Primidone; Protein Binding; Temporal Lobe; Ultrafiltration | 1974 |
Erythrocyte uptake and plasma binding of diphenylhydantoin.
Topics: Carbon Radioisotopes; Dialysis; Erythrocytes; Ethosuximide; Female; Hematocrit; Humans; Hydroxylation; Liver Cirrhosis; Male; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Protein Binding; Sulfamethoxypyridazine; Time Factors; Uremia | 1974 |
Delivery of anticonvulsant drug therapy in epileptic patients assessed by plasma level analyses.
Topics: Adolescent; Adult; Child; Chromatography, Gas; Drug Therapy; Electroencephalography; Epilepsy; Humans; Institutional Practice; Middle Aged; Phenobarbital; Phenytoin; Primidone; Recurrence; Time Factors | 1974 |
Controlled evaluation of primidone and diphenyllhydantoin sodium. Comparative anticonvulsant efficacy and toxicity in children.
Topics: Adolescent; Child; Child, Preschool; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Infant; Phenytoin; Primidone | 1968 |
[Results of treatment of epilepsy in children up to 14 years of age].
Topics: Adolescent; Age Factors; Barbiturates; Child; Child, Preschool; Diazepam; Drug Synergism; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Infant; Phenobarbital; Phenytoin; Primidone | 1971 |
Influence of certain anticonvulsants on the concentration of -aminobutyric acid in the cerebral hemispheres of mice.
Topics: Aminobutyrates; Animals; Anticonvulsants; Barbiturates; Brain Chemistry; Drug Antagonism; Drug Interactions; Hydantoins; Isoniazid; Male; Mice; Phenobarbital; Phenytoin; Primidone; Stimulation, Chemical | 1972 |
Minor epileptic status.
Topics: Brain Diseases; Child; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Phenytoin; Primidone | 1972 |
Coarse facies, calvarial thickening and hyperphosphatasia associated with long-term anticonvulsant therapy.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Child; Diazepam; Ethosuximide; Facial Expression; Gingival Hyperplasia; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Skull; Time Factors | 1972 |
An isothermal GLC determination of the plasma levels of carbamazepine, diphenylhydantoin, phenobarbitone and primidone.
Topics: Benzyl Compounds; Carbamazepine; Chloroform; Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Phthalic Acids; Primidone; Solubility; Spectrophotometry; Ultraviolet Rays | 1972 |
[Vitamins and medicines. New and complicated relations].
Topics: Arthritis, Rheumatoid; Aspirin; Drug Combinations; Drug Interactions; Epilepsy; Humans; Phenytoin; Primidone; Vitamins | 1972 |
Altered calcium metabolism due to anticonvulsant drugs.
Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Arthrography; Calcium; Calcium Metabolism Disorders; Child; Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Phosphates; Primidone; Succinimides; Vitamin D | 1972 |
Long-term administration of antiepileptic drugs and the development of rickets.
Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Diazepam; Ethosuximide; Female; Gluconates; Humans; Infant; Mephobarbital; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone; Radiography; Rickets; Seizures; Time Factors; Trimethadione; Vitamin D | 1972 |
Antiepileptic drug concentrations in plasma. Clinical evaluation of 321 estimations in 237 unselected patients.
Topics: Carbamazepine; Chromatography, Gas; Chromatography, Thin Layer; Epilepsy; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1972 |
Treatment of epilepsy in the light of determinations of the blood levels of anticonvulsants.
Topics: Adult; Child; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1972 |
Osteomalacia accompanying chronic anticonvulsant therapy.
Topics: Adolescent; Alkaline Phosphatase; Biopsy; Bone and Bones; Calcium; Epilepsy; Humans; Hydroxyproline; Male; Osteomalacia; Parathyroid Hormone; Phenytoin; Primidone; Radiography; Vitamin D Deficiency | 1972 |
GLC determination of carbamazepine in plasma.
Topics: Benzocycloheptenes; Carbamates; Carbamazepine; Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1972 |
[Speech disorders in children with cerebral convulsions].
Topics: Adolescent; Barbiturates; Carbamazepine; Drug Hypersensitivity; Electroencephalography; Epilepsy; Ethosuximide; Humans; Male; Phenobarbital; Phenytoin; Primidone; Speech Disorders; Speech Therapy; Verbal Behavior | 1972 |
Rickets following anticonvulsant therapy.
Topics: Child, Preschool; Humans; Infant; Male; Phenobarbital; Phenytoin; Primidone; Rickets; Vitamin D | 1972 |
Epilepsy in multiple sclerosis.
Topics: Adolescent; Adult; Barbiturates; Basal Ganglia; Carbamazepine; Cerebral Cortex; Demyelinating Diseases; Diazepam; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Male; Multiple Sclerosis; Phenytoin; Primidone | 1972 |
[Dialysis of drugs and poisons. 2].
Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine | 1972 |
Effects of anticonvulsant drugs on chromosomes.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Embryo, Mammalian; Female; Fertility; Mice; Mitosis; Phenytoin; Pregnancy; Primidone | 1971 |
[Treatment of epilepsy in the light of the determination of the anticonvulsant blood level].
Topics: Administration, Oral; Age Factors; Anticonvulsants; Drug Synergism; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Sex Factors; Time Factors | 1971 |
Bone density in patients receiving long-term anticonvulsant therapy.
Topics: Absorptiometry, Photon; Adult; Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Epilepsy; Female; Forearm; Heel; Humans; Iodine Radioisotopes; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone | 1971 |
Variation in response to anticonvulsants in a group of epileptic patients.
Topics: Epilepsy, Temporal Lobe; Female; Humans; Male; Mental Disorders; Phenobarbital; Phenytoin; Primidone | 1971 |
[Considerations apropos of drug treatment of 1,217 epileptic patients. 3: Study in relation to the drugs used].
Topics: Barbiturates; Drug Evaluation; Drug Synergism; Epilepsy; Humans; Phenytoin; Primidone | 1971 |
Anticonvulsant therapy, folic acid and vitamin B12 metabolism and mental symptoms.
Topics: Adult; Anemia, Macrocytic; Female; Folic Acid Deficiency; Humans; Male; Mental Disorders; Middle Aged; Phenobarbital; Phenytoin; Primidone; Seizures; Vitamin B 12 Deficiency | 1966 |
Influence of ethylphenacemide on serum levels of other anti-epileptic drugs.
Topics: Adolescent; Adult; Benzazepines; Butyrates; Chromatography, Thin Layer; Colorimetry; Drug Synergism; Humans; Male; Phenobarbital; Phenytoin; Primidone; Urea | 1970 |
A clinical study of serum primidone levels.
Topics: Administration, Oral; Adolescent; Adult; Biotransformation; Child; Child, Preschool; Chromatography, Gas; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1970 |
Management of hemiplegic child. Role of neurologist.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Hemiplegia; Humans; Infant; Infant, Newborn; Phenobarbital; Phenytoin; Primidone | 1971 |
Anticonvulsant drugs and folic acid in young mentally retarded epileptic patients. A study of serum folate, fit frequency and I.Q.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Folic Acid; Humans; Intellectual Disability; Intelligence Tests; Male; Phenobarbital; Phenytoin; Primidone; Prognosis | 1971 |
Osteomalacia with long-term anticonvulsant therapy in epilepsy.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Biopsy; Calcium; Enzyme Induction; Epilepsy; Ergocalciferols; Female; Humans; Male; Middle Aged; Osteomalacia; Phenytoin; Phosphorus; Primidone; Vitamin D | 1970 |
Intolerance to diphenylhydantoin in five cases of Vogt-Spielmeyer disease.
Topics: Ataxia; Brain; Humans; L-Lactate Dehydrogenase; Lipidoses; Phenobarbital; Phenytoin; Primidone; Seizures | 1969 |
Central effects of diphenylhydantoin (dilantin) in epileptic oligophrenics during phenobarbital-primidone withdrawal, sodium bicarbonate, and ammonium chloride administration.
Topics: Adolescent; Adult; Ammonium Chloride; Bicarbonates; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Intellectual Disability; Lipidoses; Male; Phenobarbital; Phenytoin; Primidone; Sodium | 1969 |
Central effect of diphenylhydantoin (Dilantin) in epileptic oligophrenics during phenobarbital-primidone withdrawal, sodium bicarbonate, and ammonium chloride administration.
Topics: Adolescent; Adult; Ammonium Chloride; Bicarbonates; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Intellectual Disability; Lipidoses; Male; Phenobarbital; Phenytoin; Primidone; Sodium | 1969 |
Simultaneous measurement of diphenylhydantoin and primidone in serum by gas-liquid chromatography.
Topics: Barbiturates; Blood Chemical Analysis; Chromatography, Gas; Glutethimide; Humans; Methods; Phenytoin; Primidone; Time Factors | 1970 |
Concurrent assay of phenobarbital and diphenylhydantoin in plasma by vapor-phase chromatography.
Topics: Chloroform; Chromatography, Gas; Humans; Hydrogen-Ion Concentration; Methods; Phenobarbital; Phenytoin; Primidone; Solubility; Time Factors | 1970 |
Classical hysterical seizures facilitated by anticonvulsant toxicity.
Topics: Achondroplasia; Adolescent; Adult; Electroencephalography; Epilepsy; Female; Humans; Hysteria; Male; Phenytoin; Primidone | 1970 |
Disturbance of calcium metabolism by anticonvulsant drugs.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Anticonvulsants; Calcium Metabolism Disorders; Enzyme Induction; Epilepsy; Female; Humans; Hypocalcemia; Isoenzymes; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Phosphorus; Primidone; Vitamin D; Vitamin D Deficiency | 1970 |
'Idiopathic epilepsy'.
Topics: Epilepsy; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Phenytoin; Primidone; Prognosis | 1970 |
Quantitative estimation of diphenylhydantoin, primidone and phenobarbital in plasma by gas-liquid chromatography.
Topics: Aniline Compounds; Chromatography, Gas; Hot Temperature; Humans; Methods; Methylation; Phenobarbital; Phenytoin; Primidone | 1970 |
The distribution of plasma phenytoin levels in epileptic patients.
Topics: Adult; Drug Tolerance; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1970 |
The importance of gastric lavage in the treatment of poisoning.
Topics: Amobarbital; Barbiturates; Chloroform; Chromatography, Thin Layer; Forensic Medicine; Gastric Lavage; Humans; Phenobarbital; Phenytoin; Poisoning; Primidone; Secobarbital | 1970 |
Salicylate intoxication and the CNS with special reference to EEG findings.
Topics: Adult; Central Nervous System Diseases; Electroencephalography; Humans; Male; Phenytoin; Poisoning; Primidone; Salicylates | 1971 |
Rickets and anticonvulsant therapy in children: a roentgenologic investigation.
Topics: Adolescent; Anticonvulsants; Benzazepines; Child; Dextroamphetamine; Diazepam; Ethosuximide; Female; Hand; Humans; Knee; Male; Methylphenidate; Phenobarbital; Phenytoin; Primidone; Radiography; Rickets; Thioridazine; Time Factors | 1971 |
[Congenital abnormalities, cleft lip and cleft palate in particular, in children of epileptic mothers].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Cleft Lip; Cleft Palate; Epilepsy; Female; Humans; Infant, Newborn; Parity; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone | 1971 |
Gas chromatographic assay of underivatized 5,5-diphenylhydantoin (dilantin) in plasma extracts.
Topics: Carbamazepine; Chloroform; Chromatography, Gas; Coma; Epilepsy; Humans; Hydrogen-Ion Concentration; Methods; Phenobarbital; Phenytoin; Primidone | 1971 |
[Correlation between the prescribed dose of anti-epileptic agents and the blood levels measured].
Topics: Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone | 1971 |
Amino acid composition of the Ammon's horn and the effect of anticonvulsant drugs.
Topics: Amino Acids; Animals; Anticonvulsants; Body Weight; Brain Chemistry; Chromatography, Paper; DNA; Hippocampus; Injections, Intraperitoneal; Male; Phenytoin; Primidone; Rats; Trimethadione | 1967 |
Pseudolymphoma syndrome. A sensitivity to anticonvulsant drugs.
Topics: Biopsy; Blood Cell Count; Blood Chemical Analysis; Chlordiazepoxide; Drug Hypersensitivity; Female; Humans; Hydantoins; Hydrochlorothiazide; Lymphoma; Middle Aged; Phenobarbital; Phenytoin; Primidone; Seizures | 1968 |
Folic acid deficiency from anticonvulsant therapy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant; Male; Mental Processes; Phenobarbital; Phenytoin; Primidone; Protein Biosynthesis | 1968 |
Gastrointestinal dysfunction in anticonvulsant megaloblastic anaemia.
Topics: Adult; Anemia, Macrocytic; Female; Folic Acid Deficiency; Gastrointestinal Diseases; Humans; Phenytoin; Primidone | 1968 |
Acute diphenylhydantoin and primidone poisoning treated by peritoneal dialysis.
Topics: Adult; Humans; Male; Peritoneal Dialysis; Phenytoin; Primidone; Suicide | 1968 |
[The necessary dosis of antiepileptic drugs in epileptic children during their growth period].
Topics: Adolescent; Adult; Anticonvulsants; Barbiturates; Body Weight; Child; Child Development; Child, Preschool; Epilepsy; Ethosuximide; Female; Growth; Humans; Infant; Male; Oxyphenbutazone; Phenytoin; Primidone | 1968 |
[Pharmacologic properties of partially purified glutamic acid decarboxylase (L-glutamate-1-carboxylyase, E.C. 4.1.1.15) from calf cerebral cortex].
Topics: Animals; Antidepressive Agents; Barbiturates; Carboxy-Lyases; Cattle; Cerebral Cortex; Chemical Phenomena; Chemistry; Chlorpromazine; Codeine; Glutamates; Hydantoins; Imipramine; Lysergic Acid Diethylamide; Phenethylamines; Phenytoin; Primidone; Psilocybin; Pyrrolidines; Spectrophotometry | 1968 |
Mental effects of anticonvulsants, and folic acid metabolism.
Topics: Age Factors; Anemia, Macrocytic; Anticonvulsants; Brain; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Intellectual Disability; Male; Mental Disorders; Peripheral Nerves; Phenobarbital; Phenytoin; Primidone; Psychotic Disorders; Sex Factors; Spinal Cord; Vitamin B 12 | 1968 |
Thin-layer chromatography of anticonvulsant drugs.
Topics: Anticonvulsants; Chromatography, Thin Layer; Epilepsy; Humans; Hydantoins; Methods; Phenobarbital; Phenytoin; Primidone; Solvents; Time Factors | 1969 |
Ten years EEG studies in epileptic children (two cases).
Topics: Adolescent; Child; Child, Preschool; Electroencephalography; Emotions; Epilepsy; Humans; Mephobarbital; Phenytoin; Primidone; Trimethadione | 1969 |
Hyperglycemia with relative hypoinsulinemia in diphenylhydantoin toxicity.
Topics: Adolescent; Arginine; Blood Glucose; Female; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Phenobarbital; Phenytoin; Primidone | 1969 |
Gas chromatographic analysis for anticonvulsant drugs in biologic fluids.
Topics: Anticonvulsants; Chromatography, Gas; Equipment and Supplies; Humans; Hydantoins; Methods; Phenobarbital; Phenytoin; Primidone; Time Factors | 1969 |
Folic acid and anticonvulsive drugs.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsy; Erythrocyte Count; Female; FIGLU Test; Folic Acid; Folic Acid Deficiency; Hematocrit; Humans; Male; Middle Aged; Neutrophils; Phenobarbital; Phenytoin; Primidone; Psychotic Disorders; Vitamin B 12 | 1969 |
Methylphenidate interaction with both anticonvulsants and ethyl biscoumacetate.
Topics: Adult; Anticonvulsants; Ataxia; Brain Diseases; Child, Preschool; Depression, Chemical; Ethyl Biscoumacetate; Humans; In Vitro Techniques; Infant; Liver; Male; Methylphenidate; Phenobarbital; Phenytoin; Primidone | 1969 |
A sequential screning test based on the running component of audiogenic seizures in mice, including reference compound PD50 values.
Topics: Acetazolamide; Animals; Anticonvulsants; Atropine; Chloral Hydrate; Chlordiazepoxide; Ethosuximide; Haloperidol; Hydroxybutyrates; Hypnotics and Sedatives; Meprobamate; Methods; Mice; Motor Activity; Orphenadrine; Phenobarbital; Phenytoin; Primidone; Sound | 1969 |
The estimation of some important anticonvulsant drugs in serum.
Topics: Anticonvulsants; Blood Chemical Analysis; Chemistry, Clinical; Chromatography, Thin Layer; Colorimetry; Humans; In Vitro Techniques; Phenobarbital; Phenytoin; Primidone | 1966 |
Drug-induced systemic lupus erythematosus. Primidone as a possible cause.
Topics: Electroencephalography; Epilepsy; Female; Humans; Hydralazine; Hydroxychloroquine; Lupus Erythematosus, Systemic; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1966 |
Disulfiramum (antabuse) as inhibitor of phenytoin metabolism.
Topics: Adult; Disulfiram; Drug Antagonism; Humans; Male; Phenobarbital; Phenytoin; Primidone; Spectrophotometry | 1966 |
The influence of disulfiram and calcium carbimide on the serum diphenylhydantoin. Excretion of HPPH in the urine.
Topics: Acetazolamide; Adult; Aged; Alcoholism; Amitriptyline; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Cyanates; Disulfiram; Drug Synergism; Epilepsy; Humans; Hydroflumethiazide; Imipramine; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1967 |
Psychiatric implications of anticonvulsant drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
Choice of anticonvulsants in epilepsy.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Epilepsy; Ethosuximide; Follow-Up Studies; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
Mechanisms of action of antiepileptic drugs.
Topics: Acetazolamide; Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Chemical Phenomena; Chemistry; Humans; Paraldehyde; Phenytoin; Primidone; Seizures; Succinimides; Trimethadione; Valproic Acid | 1982 |
The influence of antiepileptic drugs on the electroencephalogram: a review of controlled clinical studies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
[Rise in gamma-GT during anticonvulsive therapy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
Pharmacokinetics of antiepileptic drugs.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Ethosuximide; Female; Half-Life; Humans; Infant; Infant, Newborn; Intestinal Absorption; Kinetics; Male; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Valproic Acid | 1983 |
Pharmacodynamic factors in the occurrence of psychiatric symptoms among patients with epilepsy.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Epilepsy; Folic Acid; Humans; Kinetics; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid; Vitamin B 12 | 1983 |
A rapid gas liquid chromatography method for simultaneous determination of various anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Therapeutic aspects of kinesiogenic paroxysmal choreoathetosis and familial paroxysmal choreoathetosis of the Mount and Reback type.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Athetosis; Carbamazepine; Child; Chorea; Female; Haloperidol; Humans; Male; Middle Aged; Motor Activity; Pedigree; Phenytoin; Primidone; Valproic Acid | 1983 |
Plasma arginine vasopressin concentrations in epileptics under monotherapy.
Topics: Adult; Anticonvulsants; Arginine Vasopressin; Carbamazepine; Epilepsy; Humans; Phenytoin; Primidone; Valproic Acid | 1983 |
[Treatment of rapid nodding "salaam" spasms in childhood].
Topics: Adrenocorticotropic Hormone; Child, Preschool; Clonazepam; Electroencephalography; Female; Humans; Infant; Infant, Newborn; Male; Nitrazepam; Phenytoin; Primidone; Psychomotor Disorders; Spasms, Infantile; Valproic Acid | 1980 |
Peripheral neuropathy in epileptic patients.
Topics: Epilepsy; H-Reflex; Humans; Neural Conduction; Peripheral Nervous System Diseases; Peroneal Nerve; Phenobarbital; Phenytoin; Primidone; Sural Nerve | 1981 |
Anticonvulsant peripheral neuropathy: a clinical and electrophysiological study of patients on single drug treatment with phenytoin, carbamazepine or barbiturates.
Topics: Adolescent; Adult; Aged; Barbiturates; Carbamazepine; Evoked Potentials, Somatosensory; Humans; Median Nerve; Middle Aged; Neural Conduction; Peripheral Nervous System Diseases; Phenobarbital; Phenytoin; Primidone; Sural Nerve | 1982 |
Logit-log calibration curves for EMIT assays.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Glucose-6-Phosphate; Glucosephosphates; Humans; Immunoenzyme Techniques; Kinetics; Mathematics; NAD; Phenobarbital; Phenytoin; Primidone; Spectrophotometry | 1983 |
Adaptation of microvolume EMIT assays for theophylline, phenobarbital, phenytoin, carbamazepine, primidone, ethosuximide, and gentamicin to a CentrifiChem chemistry analyzer.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Centrifugation; Ethosuximide; Gentamicins; Humans; Immunoenzyme Techniques; Microchemistry; Phenobarbital; Phenytoin; Primidone; Theophylline | 1983 |
Simultaneous measurement of ethosuximide, primidone, phenobarbital, phenytoin, carbamazepine, and their bioactive metabolites by liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1984 |
Generalized tonic-clonic seizures in patients with complex-partial seizures: natural history and prognostic relevance.
Topics: Carbamazepine; Epilepsies, Myoclonic; Epilepsy, Temporal Lobe; Humans; Phenytoin; Primidone; Prognosis | 1983 |
Therapeutic monitoring of serum antiepileptic drug levels.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Laboratories; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid | 1983 |
Antiepileptic drugs and teratogenesis. How should patients, doctors and health authorities be counselled?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newborn; Oxazoles; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Risk; Trimethadione; Valproic Acid | 1983 |
Treatment of the nonconvulsive epilepsies.
Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1983 |
[Pharmacotherapy of epilepsy--current problems and controversies].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Seizures, Febrile; Status Epilepticus; Valproic Acid | 1983 |
Unnecessary polypharmacy in patients with frequent seizures.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Enzyme induction in neonates after fetal exposure to antiepileptic drugs.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Anticonvulsants; Breath Tests; Carbamazepine; Carbon Radioisotopes; Enzyme Induction; Female; Humans; Infant, Newborn; Liver; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1983 |
A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients.
Topics: Anticonvulsants; Antipyrine; Carbamazepine; Enzyme Induction; Epilepsy; Female; Glucaric Acid; Half-Life; Humans; Immunoenzyme Techniques; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Pharmacologic therapy of seizures in the elderly.
Topics: Aged; Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Status Epilepticus; Valproic Acid | 1984 |
[Plasma levels of antiepileptic agents in the treatment of epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
One drug for childhood grand mal: medical audit for three-year remissions.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Fetal exposure to anticonvulsant drugs. Detailed pathological study of a case.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Adult; Anticonvulsants; Brain; Cardiomegaly; Epilepsy; Ethosuximide; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Microscopy, Electron; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Purkinje Cells | 1980 |
Primidone therapy in refractory neonatal seizures.
Topics: Drug Therapy, Combination; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Primidone; Seizures | 1984 |
[Simultaneous determination of 4 anticonvulsant drugs by high pressure liquid chromatography (HPLC)].
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone | 1984 |
Excretion of organic acids associated with biotin deficiency in chronic anticonvulsant therapy.
Topics: Adult; Anticonvulsants; Biotin; Carbamazepine; Carboxy-Lyases; Carboxylic Acids; Epilepsy; Female; Humans; Male; Methylmalonyl-CoA Decarboxylase; Phenobarbital; Phenytoin; Primidone | 1984 |
Four siblings with similar malformations after exposure to phenytoin and primidone.
Topics: Abnormalities, Drug-Induced; Child; Child Development; Child, Preschool; Embryonic and Fetal Development; Eyelids; Face; Female; Fingers; Humans; Infant; Male; Nails, Malformed; Phenotype; Phenytoin; Primidone | 1984 |
[Monitoring of antiepileptic therapy. A basis for the clinical use of plasma levels in the treatment of epilepsy].
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Ethosuximide; Humans; Phenytoin; Primidone | 1984 |
Prognosis of chronic epilepsy with complex partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; Humans; Phenobarbital; Phenytoin; Primidone; Prognosis | 1984 |
The simultaneous determination of five anti-epileptic drugs in plasma by high performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1984 |
Mutagenicity of antiepileptic drugs. II. Phenytoin, primidone and phenobarbital.
Topics: Animals; Biotransformation; Cells, Cultured; Chromosome Aberrations; Cricetinae; Female; Mutation; Ovary; Phenobarbital; Phenytoin; Primidone; Sister Chromatid Exchange | 1984 |
Dementia in epilepsy.
Topics: Adult; Anticonvulsants; Brain Injuries; Dementia; Epilepsy; Epilepsy, Temporal Lobe; Humans; Middle Aged; Phenytoin; Primidone | 1984 |
[Pharmacologically-caused eye movement disorders--differential diagnosis and mechanisms of action].
Topics: Alcoholism; Barbiturates; Cerebellar Diseases; Diagnosis, Differential; Eye Movements; Fixation, Ocular; Humans; Labyrinth Diseases; Motion Perception; Nystagmus, Pathologic; Nystagmus, Physiologic; Ophthalmoplegia; Phenytoin; Primidone; Psychotropic Drugs; Saccades; Vestibule, Labyrinth | 1983 |
Reduction of polypharmacy for epilepsy in an institution for the retarded.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Intellectual Disability; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1983 |
[Direct and indirect parameters of free thyroxine. I. Method, quality control and in vitro experiments on storage of samples and effect of drugs].
Topics: Aspirin; Blood Preservation; Drug Interactions; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Radioimmunoassay; Thyroxine | 1983 |
A design for the prospective evaluation of the efficacy and toxicity of antiepileptic drugs in adults.
Topics: Adult; Aged; Anticonvulsants; Behavior; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Electroencephalography; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Random Allocation; Seizures | 1983 |
Antiepileptic agents--primidone, phenobarbital, phenytoin, and carbamazepine by reversed-phase liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone; Statistics as Topic | 1984 |
Compromised hepatic function in dogs treated with anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Combination; Liver; Liver Cirrhosis; Phenytoin; Primidone; Prospective Studies; Seizures | 1984 |
Serum concentrations and efficacy of phenytoin, phenobarbital, and primidone in canine epilepsy.
Topics: Animals; Dog Diseases; Dogs; Drug Therapy, Combination; Epilepsy; Phenobarbital; Phenytoin; Primidone | 1984 |
[Anticonvulsive combined therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
Therapeutic alternatives in phenytoin-induced gingival hyperplasia. A case report and discussion.
Topics: Adolescent; Epilepsy; Female; Gingival Hyperplasia; Humans; Phenytoin; Primidone; Valproic Acid | 1980 |
Hepatotoxicity of sodium valproate and other anticonvulsants in rat hepatocyte cultures.
Topics: Animals; Anticonvulsants; Clonazepam; Culture Techniques; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Liver; Phenobarbital; Phenytoin; Primidone; Rats; Valproic Acid | 1980 |
[Problems of therapeutic service in primidone therapy].
Topics: Adolescent; Drug Administration Schedule; Drug Interactions; Epilepsy, Tonic-Clonic; Female; Half-Life; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
Monotherapy or polytherapy for epilepsy?
Topics: Adolescent; Adult; Carbamazepine; Clonazepam; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1981 |
Anticonvulsant-induced status epilepticus in Lennox-Gastaut syndrome.
Topics: Adolescent; Adult; Benzodiazepinones; Carbamazepine; Child; Child, Preschool; Chlormethiazole; Clonazepam; Diazepam; Drug Combinations; Electroencephalography; Epilepsy, Absence; Female; Humans; Phenytoin; Primidone; Status Epilepticus | 1981 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1981 |
Daily fluctuations of dipropylacetate (DPA) serum level in epileptic patients.
Topics: Adolescent; Adult; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Primidone; Time Factors; Valproic Acid | 1980 |
Drugs in the treatment of tinnitus.
Topics: Amobarbital; Antidepressive Agents, Tricyclic; Carbamazepine; Ethanol; Humans; Lidocaine; Phenytoin; Primidone; Tinnitus; Valproic Acid | 1981 |
[The distribution of drugs between plasma, brain and cerebrospinal fluid in the human].
Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Carbamazepine; Diazepam; Humans; Lithium; Nordazepam; Phenobarbital; Phenytoin; Primidone; Protein Binding; Psychotropic Drugs; Serum Albumin; Sulfamerazine | 1982 |
EEG quantification of drug level effects in monkey model of partial epilepsy.
Topics: Animals; Anticonvulsants; Circadian Rhythm; Clonazepam; Disease Models, Animal; Electroencephalography; Kinetics; Macaca mulatta; Male; Phenobarbital; Phenytoin; Primidone; Seizures; Valproic Acid | 1982 |
Two antiepileptic drugs for intractable epilepsy with complex-partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
[A study on cerebrospinal fluid and saliva to serum concentration ratios of anticonvulsants--Phenytoin, Phenobarbital, Valproic Acid and Primidone in epileptic patients].
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Saliva; Valproic Acid | 1982 |
Simultaneous very fast liquid-chromatographic analysis of ethosuximide, primidone, phenobarbital, phenytoin, and carbamazepine in serum.
Topics: Carbamazepine; Chromatography, Liquid; Economics; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1983 |
[Monitoring therapy by analysis of the drug concentration of saliva].
Topics: Anticonvulsants; Carbamazepine; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Saliva | 1983 |
Simultaneous liquid chromatographic determination of chloramphenicol and antiepileptic drugs (phenobarbital, phenytoin, carbamazepine, and primidone) in plasma.
Topics: Adult; Anticonvulsants; Carbamazepine; Chloramphenicol; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1983 |
Serum concentration of clonazepam and the therapeutic effect of the drug.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Clonazepam; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1983 |
Simultaneous high performance liquid-chromatographic determination of carbamazepine, carbamazepine-10,11-epoxide, ethosuximide, phenobarbital, phenytoin, primidone and phenylethylmalonamide in plasma.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1983 |
Improved isocratic liquid-chromatographic simultaneous measurement of phenytoin, phenobarbital, primidone, carbamazepine, ethosuximide, and N-desmethylmethsuximide in serum.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Reference Values; Succinimides | 1982 |
Quantitative simultaneous determination of eight common antiepileptic drugs and metabolites by liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Succinimides | 1981 |
Epileptic seizures controlled with paramethadione/primidone.
Topics: Animals; Dog Diseases; Dogs; Drug Therapy, Combination; Epilepsy; Male; Oxazoles; Phenytoin; Primidone | 1981 |
The medical treatment of tinnitus.
Topics: Adult; Carbamazepine; Diethylcarbamazine; Female; Humans; Lidocaine; Myoclonus; Phenytoin; Primidone; Tinnitus | 1981 |
On-line liquid-chromatographic analysis for drugs in serum with the Technicon "FAST-LC" system: performance data for theophylline and for four commonly used anticonvulsants and their metabolites.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1980 |
[A gas-chromatographic method for the determination of carbamazepine, phenobarbital, phenytoin and primidone in the same extract of serum (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Temperature | 1980 |
Emit assays for five major anticonvulsant drugs. An evaluation of adaptations to two discrete kinetic analyzers.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Cross Reactions; Ethosuximide; Evaluation Studies as Topic; Humans; Immunoenzyme Techniques; Indicators and Reagents; Phenobarbital; Phenytoin; Primidone | 1980 |
Rapid centrifugal analyzer enzyme immunoassays for phenytoin, phenobarbital, and primidone.
Topics: Computers; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Reagent Kits, Diagnostic | 1980 |
Enzyme immunoassay of phenobarbital, phenytoin, primidone, carbamazepine and theophylline with the Abbott VP Bichromatic Analyzer.
Topics: Carbamazepine; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1981 |
[The determination of anticonvulsant drug levels in blood by enzyme immunoassay: method and clinical application (author's transl)].
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Immunoenzyme Techniques; Male; Phenobarbital; Phenytoin; Primidone | 1980 |
Monitoring of therapeutic serum concentrations of antiepileptic drugs by a newly developed gas chromatographic procedure and enzyme immunoassay (EMIT): a comparative study.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Quality Control | 1981 |
Phenytoin: an inhibitor and inducer of primidone metabolism in an epileptic patient.
Topics: Adult; Drug Interactions; Epilepsy; Female; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1982 |
Hepatic cirrhosis associated with long-term anticonvulsant drug therapy in dogs.
Topics: Animals; Anticonvulsants; Dog Diseases; Dogs; Female; Liver; Liver Cirrhosis; Male; Microscopy, Electron; Phenobarbital; Phenytoin; Primidone | 1982 |
Plasma levels and clinical effects of antiepileptic drugs in pregnant epileptic patients and their newborns.
Topics: Adult; Anticonvulsants; Clonazepam; Epilepsy; Female; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone | 1980 |
The effects of phenytoin on phenobarbitone and primidone metabolism.
Topics: Adult; Aged; Anticonvulsants; Drug Therapy, Combination; Humans; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1981 |
[Phenobarbital intoxication in a patient with primidone and diphenylhydantoin (author's transl)].
Topics: Adult; Drug Interactions; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1980 |
Rapid determination of anticonvulsant drugs by isothermal gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1981 |
Ictal effects of anticonvulsant medication withdrawal in epileptic patients.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome | 1981 |
Chromosomal investigations in epileptic children during long-term therapy with phenytoin or primidone.
Topics: Adolescent; Cells, Cultured; Child; Child, Preschool; Chromosome Aberrations; Chromosomes, Human; Epilepsy; Humans; Lymphocytes; Phenytoin; Primidone | 1981 |
Rapid microanalysis of anticonvulsants by high-performance thin-layer chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Thin Layer; Humans; Phenobarbital; Phenytoin; Primidone; Reference Values | 1981 |
[Gas chromatographic determination of phenytoin, phenobarbital and primidone: flash-methylation after direct addition of trimethyl-phenyl-ammonium hydroxide to the ethyl acetate extract (author's transl)].
Topics: Aniline Compounds; Chromatography, Gas; Humans; Methylation; Phenobarbital; Phenytoin; Primidone; Quaternary Ammonium Compounds | 1981 |
Effect of anticonvulsant and antidepressant drugs on iodothyronines in serum.
Topics: Adult; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Dose-Response Relationship, Drug; Female; Humans; Male; Mianserin; Phenobarbital; Phenytoin; Primidone; Thyroid Hormones | 1980 |
Antiepileptic drug levels and side effects in man.
Topics: Anticonvulsants; Electroencephalography; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Role of carbamazepine in reducing polypharmacy in epilepsy.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1981 |
Spectrophotometric determination of phenytoin in the presence of other anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Diazepam; Humans; Phenobarbital; Phenytoin; Primidone; Spectrophotometry, Ultraviolet | 1981 |
Improvement in antiepileptic drug levels following reduction of intervals between clinic visits.
Topics: Adolescent; Adult; Anticonvulsants; Appointments and Schedules; Carbamazepine; Epilepsy; Ethosuximide; Female; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1980 |
Measurement of anticonvulsants in serum by reversed-phase ion-pair liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Urea | 1980 |
Antiepileptic drug distribution in cerebral cortex, ammon's horn, and amygdala in man.
Topics: Adolescent; Adult; Amygdala; Anticonvulsants; Carbamazepine; Cerebral Cortex; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1980 |
Improved gas--liquid chromatographic method for the simultaneous determination of phenobarbital, phenytoin, carbamazepine and primidone in biological fluids.
Topics: Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
High performance liquid chromatographic analysis of anti-convulsant drugs using radial compression columns.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Monitoring 2-ethyl-2-phenylmalonamide in serum by gas-liquid chromatography: application to retrospective study in epilepsy patients dosed with primidone.
Topics: Adult; Carbamazepine; Chromatography, Gas; Drug Interactions; Epilepsy; Humans; Malonates; Middle Aged; Phenylethylmalonamide; Phenytoin; Primidone | 1980 |
[Rational control of calcium metabolism in children treated with anticonvulsants].
Topics: Adolescent; Anticonvulsants; Calcium; Child; Child, Preschool; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
The effect of medication on interaural time and intensity discrimination in a hemispherectomee.
Topics: Adult; Brain; Brain Diseases; Female; Humans; Loudness Perception; Phenytoin; Primidone | 1980 |
[Biotransformation of some antiepileptic drugs (author's transl)].
Topics: Anticonvulsants; Biotransformation; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Power spectral analysis of EEG characteristics during sleep in epileptics.
Topics: Adolescent; Adult; Carbamazepine; Circadian Rhythm; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Sleep, REM | 1981 |
Diphenylhydantoin and primidone in tears.
Topics: Adult; Child; Epilepsy; Female; Humans; Male; Phenytoin; Primidone; Saliva; Tears | 1981 |
Practical considerations in anticonvulsant therapy--Part 2.
Topics: Anticonvulsants; Benzodiazepines; Cost Control; Epilepsy; Ethosuximide; Humans; Monitoring, Physiologic; Patient Compliance; Patient Education as Topic; Pharmacists; Phenobarbital; Phenytoin; Primidone; Role; Valproic Acid | 1995 |
The anticonvulsant hypersensitivity syndrome.
Topics: Adult; Anticonvulsants; Bronchial Diseases; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Facial Dermatoses; Female; Humans; Male; Middle Aged; Pharyngitis; Phenytoin; Primidone; Stevens-Johnson Syndrome; Urticaria | 1993 |
Treatment of "benign" partial epilepsies of childhood, including atypical forms.
Topics: Adrenocorticotropic Hormone; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Brain; Carbamazepine; Child; Child, Preschool; Clobazam; Electroencephalography; Epilepsies, Partial; Humans; Phenytoin; Primidone; Sleep, REM; Thiazines; Treatment Outcome | 1995 |
Comparison of community and institutional prescription of antiepileptic drugs for individuals with learning disabilities.
Topics: Adult; Ambulatory Care; Anticonvulsants; Cognition Disorders; Day Care, Medical; Drug Therapy, Combination; Drug Utilization; England; Epilepsy; Female; Humans; Institutionalization; Intellectual Disability; Intelligence; Male; Phenobarbital; Phenytoin; Primidone; Social Behavior; State Medicine | 1994 |
Delayed fatal agranulocytosis in an epileptic taking primidone and phenytoin.
Topics: Adult; Agranulocytosis; Drug Therapy, Combination; Epilepsy; Fatal Outcome; Humans; Male; Phenytoin; Primidone | 1994 |
Epilepsy treatment in The Netherlands. Comparison of matched groups of two medical centres.
Topics: Adolescent; Adult; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Female; gamma-Aminobutyric Acid; Humans; Male; Netherlands; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Statistics, Nonparametric; Treatment Outcome; Valproic Acid; Vigabatrin | 1994 |
Factors affecting the determination of drugs and endogenous low molecular mass compounds in human serum by micellar electrokinetic capillary chromatography with direct sample injection.
Topics: Anticonvulsants; Blood Chemical Analysis; Buffers; Capillary Action; Chromatography; Ethosuximide; Humans; Kinetics; Micelles; Molecular Weight; Naproxen; Osmolar Concentration; Phenobarbital; Phenytoin; Primidone | 1994 |
Simultaneous determination of felbamate, primidone, phenobarbital, carbamazepine, two carbamazepine metabolites, phenytoin, and one phenytoin metabolite in human plasma by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Quality Control; Regression Analysis; Spectrophotometry, Ultraviolet | 1994 |
Metabolic bone disease (anticonvulsant osteomalacia) and renal tubular acidosis in tuberous sclerosis.
Topics: Acidosis, Renal Tubular; Adult; Back Pain; Bicarbonates; Bone and Bones; Calcitriol; Calcium; Calcium Carbonate; Drug Therapy, Combination; Epilepsy; Female; Humans; Intestinal Absorption; Neural Conduction; Osteomalacia; Phenytoin; Primidone; Tuberous Sclerosis | 1993 |
Simultaneous determination of carbamazepine, phenytoin, phenobarbital, primidone and their principal metabolites by high-performance liquid chromatography with photodiode-array detection.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Saliva; Spectrophotometry, Ultraviolet | 1993 |
Rapid switchover to carbamazepine using pharmacokinetic parameters.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsies, Partial; Female; Humans; Male; Phenytoin; Pilot Projects; Primidone; Therapeutic Equivalency | 1998 |
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenobarbital; Phenytoin; Primidone; Treatment Outcome; Valproic Acid; Vitamin B 12 | 2000 |
Seizure-inducing paradoxical reaction to antiepileptic drugs.
Topics: Anticonvulsants; Clonazepam; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Humans; Infant; Phenytoin; Primidone | 2000 |
New calixarene-bonded stationary phases in high-performance liquid chromatography: comparative studies on the retention behavior and on influences of the eluent.
Topics: Calixarenes; Chromatography, High Pressure Liquid; Macromolecular Substances; Phenytoin; Polycyclic Compounds; Primidone | 2000 |
Determination of lamotrigine simultaneously with carbamazepine, carbamazepine epoxide, phenytoin, phenobarbital, and primidone in human plasma by SPME-GC-TSD.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Lamotrigine; Phenobarbital; Phenytoin; Primidone; Triazines | 2002 |
Megaloblastic anaemia in patients treated with diphenylhydantoin and primidone.
Topics: Anemia; Anemia, Megaloblastic; Anticonvulsants; Humans; Hydantoins; Phenytoin; Primidone | 1957 |
Megaloblastic anaemia occurring during treatment of epilepsy with phenytoin sodium, primidone and phenobarbitone.
Topics: Anemia; Anemia, Megaloblastic; Anticonvulsants; Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone | 1957 |
[Now and then: development of drug treatment of epilepsy since A. Hauptmann].
Topics: Anticonvulsants; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Pyrrolidinones | 1962 |
Drug eruptions from anticonvulsant drugs. Observations on drug-induced lesions that were fixed and lupus-erythematosus-like, and on cross-reactivity between several drugs involved.
Topics: Anticonvulsants; Barbiturates; Drug Eruptions; Drug Hypersensitivity; Humans; Phenytoin; Primidone | 1963 |
Increased activity of microsomal strychnine-metabolizing enzyme induced by phenobarbital and other drugs.
Topics: Glutethimide; Meprobamate; Nikethamide; Phenobarbital; Phenytoin; Primidone; Strychnine; Thiopental; Urethane | 1962 |
Treatment of epilepsy.
Topics: Acetazolamide; Anticonvulsants; Automatism; Child; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Seizures | 1963 |
ANTIEPILEPTIC DRUGS.
Topics: Acetazolamide; Amphetamine; Amphetamines; Anticonvulsants; Barbiturates; Bromides; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Meprobamate; Phenobarbital; Phenytoin; Primidone; Succinimides; Toxicology | 1963 |
MEGALOBLASTIC ANEMIA ASSOCIATED WITH THE USE OF ANTICONVULSANT DRUGS. REPORT OF A CASE AND REVIEW OF THE LITERATURE.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Toxicology | 1963 |
MEGALOBLASTIC ANAEMIA ASSOCIATED WITH ANTICONVULSANT THERAPY.
Topics: Amobarbital; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Barbiturates; Epilepsy; Folic Acid; Humans; Metabolism; Phenobarbital; Phenytoin; Primidone; Toxicology; Vitamin B 12 | 1963 |
STUDIES ON ANTICONVULSANT AND ANTIFIBRILLATORY DRUGS.
Topics: Acetylcholine; Anticonvulsants; Atrial Fibrillation; Brain; Dogs; Metabolism; Pharmacology; Phenytoin; Primidone; Proguanil; Promethazine; Quinidine; Rats; Research | 1963 |
THORAZINE AS AN EPILEPTOGENIC AGENT.
Topics: Chlorpromazine; Epilepsy; Humans; Pharmacology; Phenytoin; Primidone; Schizophrenia | 1963 |
ANTICONVULSANT DRUGS.
Topics: Anticonvulsants; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1964 |
SUBNORMAL SERUM FOLATE AND MACROCYTOSIS ASSOCIATED WITH ANTICONVULSANT DRUG THERAPY.
Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Biological Assay; Blood Chemical Analysis; Enterococcus faecalis; Epilepsy; Folic Acid; Folic Acid Antagonists; Humans; Lactobacillus; Phenobarbital; Phenytoin; Primidone; Toxicology; Vitamin B 12 | 1964 |
MEDICAL TREATMENT OF EPILEPSIES IN CHILDHOOD. A LONG-TERM SURVEY OF 801 PATIENTS.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Child; Electroencephalography; Epilepsy; Humans; Infant; Phenobarbital; Phenytoin; Primidone; Statistics as Topic | 1963 |
PSYCHOMOTOR VARIANT TYPE OF SEIZURE DISCHARGE.
Topics: Adolescent; Anticonvulsants; Child; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Temporal Lobe | 1963 |
[TREATMENT OF EPILEPSY IN ADULTS. A BRIEF SURVEY OF THE CLINICAL PROBLEMS].
Topics: Acetazolamide; Anticonvulsants; Blood Chemical Analysis; Chloral Hydrate; Data Collection; Electroencephalography; Epilepsy; Heterocyclic Compounds; Neurosurgery; Neurosurgical Procedures; Phenobarbital; Phenytoin; Primidone; Psychology, Clinical; Social Medicine | 1964 |
SEIZURES INDUCED BY MOVEMENT: A FORM OF REFLEX EPILEPSY.
Topics: Adolescent; Athetosis; Cerebral Angiography; Diagnosis, Differential; Electroencephalography; Epilepsy; Epilepsy, Reflex; Epilepsy, Tonic-Clonic; Humans; Neurologic Examination; Phenobarbital; Phenytoin; Primidone; Reflex; Reflex, Abnormal; Seizures; Spasm | 1964 |
[MEGALOBLASTIC ANEMIA PRODUCED BY ANTICONVULSANTS].
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Argentina; Barbiturates; Blood Cell Count; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Mephobarbital; Phenytoin; Primidone; Splenomegaly; Toxicology | 1963 |
REPORT ON THE ANTI-EPILEPTIC ACTION OF TEGRETOL.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Biomedical Research; Carbamazepine; Child; Chlordiazepoxide; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Seizures; Temporal Lobe; Toxicology | 1964 |
[INHIBITION OF ELECTROCONVULSION BY THE KAVA-PYRONES DIHYDROMETHYSTICIN AND DIHYDROKAVAIN].
Topics: Anticonvulsants; Chlorpromazine; Kava; Mice; Pharmacology; Phenobarbital; Phenytoin; Primidone; Pyrones; Rats; Research; Seizures | 1964 |
ANTICONVULSANTS. I. DIBENZO(A,D)CYCLOHEPTADIENE-5-CARBOXAMIDE AND RELATED COMPOUNDS.
Topics: Amides; Anticonvulsants; Ataxia; Chemistry, Pharmaceutical; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Phenytoin; Primidone; Research; Seizures; Toxicology | 1964 |
IATROGENIC MEGALOBLASTIC ANAEMIA WITH NEUROLOGICAL COMPLICATIONS.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Brain Diseases; Cysticercosis; Drug Therapy; Epilepsy; Folic Acid; Humans; Iatrogenic Disease; Phenobarbital; Phenytoin; Primidone; Spinal Cord; Toxicology; Vitamin B 12 | 1964 |
MASSIVE LIVER CELL NECROSIS; A RETROSPECTIVE STUDY.
Topics: Anesthetics; Chemical and Drug Induced Liver Injury; Halothane; Hepatitis; Hepatitis A; Isoniazid; Massive Hepatic Necrosis; Pathology; Phenytoin; Postoperative Complications; Primidone; Retrospective Studies; Statistics as Topic; Sulfisoxazole; Toxicology | 1964 |
CHILD CARE IN GENERAL PRACTICE. CONVULSIONS IN INFANCY AND CHILDHOOD. II.
Topics: Acetazolamide; Anticonvulsants; Bromides; Child; Child Care; Chloral Hydrate; Diagnosis; Drug Therapy; Electroencephalography; Epilepsy; Ethosuximide; Family Practice; General Practice; Hospitalization; Humans; Infant; Oxyphenbutazone; Paraldehyde; Phenobarbital; Phenytoin; Primidone; Prognosis; Radiography; Seizures; Toxicology | 1965 |
[THE REPRODUCTION OF AUDIOGENIC CONVULSIONS AFTER THE PRELIMINARY ADMINISTRATION OF PYRAMIDONE TO ANIMALS].
Topics: Acetazolamide; Aminopyrine; Anticonvulsants; Antipyrine; Epilepsy, Reflex; Mice; Pharmacology; Phenobarbital; Phenytoin; Primidone; Rats; Research; Seizures; Sound; Toxicology | 1964 |
MEGALOBLASTIC ANAEMIA ASSOCIATED WITH ANTICONVULSANT DRUGS: STUDIES ON A CASE WITH FOUR RELAPSES.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Drug Therapy; Electrophoresis; Epilepsy; FIGLU Test; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Recurrence; Toxicology; Urine | 1965 |
NEUROLOGICAL SEQUELAE FOLLOWING DILANTIN OVERDOSE IN A PATIENT AND IN EXPERIMENTAL ANIMALS.
Topics: Adolescent; Ataxia; Biomedical Research; Cats; Chlordiazepoxide; Drug Therapy; Epilepsy; Humans; Neurologic Manifestations; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Poisoning; Primidone; Rats; Toxicology | 1965 |
[Leukemia in an epileptic treated with gardenal and dihydan; recovery; fatal mysoline poisoning with fatty degeneration of the liver and acute epithelial nephritis].
Topics: Anticonvulsants; Barbiturates; Epilepsy; Humans; Hydantoins; Leukemia; Leukocytosis; Liver Diseases; Nephritis; Phenobarbital; Phenytoin; Poisoning; Primidone | 1955 |
Simple and rapid micellar electrokinetic capillary chromatographic method for simultaneous determination of four antiepileptics in human serum.
Topics: Anticonvulsants; Buffers; Carbamazepine; Chromatography, Micellar Electrokinetic Capillary; Ethosuximide; Humans; Hydrogen-Ion Concentration; Osmolar Concentration; Phenytoin; Primidone; Quality Control; Sensitivity and Specificity; Sodium Dodecyl Sulfate | 2004 |
Simultaneous determination of phenytoin and dextromethorphan in urine by solid-phase extraction and HPLC-DAD.
Topics: Anticonvulsants; Antitussive Agents; Chromatography, High Pressure Liquid; Dextromethorphan; Humans; Phenytoin; Primidone; Sensitivity and Specificity; Time Factors | 2005 |
[Rapid analysis of antiepileptic drugs in human plasma by micellar electrokinetic capillary chromatography].
Topics: Anticonvulsants; Buffers; Carbamazepine; Chromatography, Micellar Electrokinetic Capillary; Clonazepam; Epilepsy; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Sensitivity and Specificity; Sodium Dodecyl Sulfate | 2006 |
Phenytoin desensitization in a child with symptomatic localization-related epilepsy.
Topics: Anticonvulsants; Child; Drug Therapy, Combination; Epilepsies, Partial; Humans; Male; Phenytoin; Primidone | 2007 |
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Drug Monitoring; Ethosuximide; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature; Triazines; Valproic Acid; Zonisamide | 2007 |
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cysteine; Dipeptides; Drug Evaluation; Epilepsy; Female; Folic Acid; Humans; Hyperhomocysteinemia; Liver; Male; Methionine; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Riboflavin; Valproic Acid; Vitamin B Deficiency | 2008 |
Novel micro-extraction by packed sorbent procedure for the liquid chromatographic analysis of antiepileptic drugs in human plasma and urine.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Humans; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Prohibitins; Sensitivity and Specificity; Solid Phase Extraction; Spectrophotometry, Ultraviolet | 2012 |
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)?
Topics: Anticonvulsants; Carbamazepine; Drug Discovery; Epilepsy; Ethosuximide; History, 20th Century; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Structure-Activity Relationship; Succinimides; Valproic Acid | 2012 |
Photochemical degradation of atenolol, carbamazepine, meprobamate, phenytoin and primidone in wastewater effluents.
Topics: Atenolol; Carbamazepine; Hydroxyl Radical; Meprobamate; Oxidants; Phenytoin; Photolysis; Primidone; Singlet Oxygen; Sunlight; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2015 |
Antiepileptic drugs: Impacts on human serum paraoxonase-1.
Topics: Amines; Anticonvulsants; Aryldialkylphosphatase; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Kinetics; Levetiracetam; Phenytoin; Piracetam; Primidone; Turkey; Valproic Acid | 2017 |
Phenytoin induced dystonia.
Topics: Anticonvulsants; Child, Preschool; Dystonia; Epilepsy; Humans; Male; Phenytoin; Primidone | 2018 |