Compounds > phenytoin

phenytoin and pregnenolone carbonitrile

phenytoin has been researched along with pregnenolone carbonitrile in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Selye, H; Taché, J; Taché, Y1
Garg, BD; Salas, M; Tuchweber, B1
Mécs, I; Selye, H; Szabo, S1
Beaulieu, T; Jago, MV; Kovacs, K; Tuchweber, B1
Ferguson, SS; Goldstein, JA; Jackson, JP; Negishi, M1
Fujiwara, R; Hirashima, R; Itoh, T; Kobayashi, Y; Michimae, H; Sasaki, A; Takemoto, H; Tukey, RH1

Other Studies

8 other study(ies) available for phenytoin and pregnenolone carbonitrile

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Inhibition of the effects of alfathesin and other steroid anesthetics by catatoxic steroids in rats.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:10

    Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Female; Ketosteroids; Phenobarbital; Phenytoin; Prednisolone; Pregnanediones; Pregnanes; Pregnenes; Pregnenolone Carbonitrile; Rats; Spironolactone; Steroids; Thyroxine; Time Factors

1975
Microsomal enzyme inducers and hypervitaminosis A in rats.
    Archives of pathology & laboratory medicine, 1976, Volume: 100, Issue:2

    Topics: Animals; Bone Diseases; Enzyme Induction; Female; Liver; Microsomes, Liver; Paralysis; Phenobarbital; Phenytoin; Pregnenolone Carbonitrile; Rats; Vitamin A; Zoxazolamine

1976
Protection by catatoxic steroids against the paralysis caused by combined treatment with thyroxine and methylphenidate.
    Neuropharmacology, 1972, Volume: 11, Issue:5

    Topics: Androstenols; Animals; Drug Synergism; Estradiol; Ethylestrenol; Female; Humans; Hydroxysteroids; Hyperkinesis; Ketosteroids; Methylphenidate; Norpregnanes; Paralysis; Phenobarbital; Phenytoin; Prednisolone; Pregnenolone Carbonitrile; Progesterone; Propionates; Rats; Rats, Inbred Strains; Spironolactone; Steroids; Thyroxine

1972
Effect of steroidal and nonsteroidal microsomal enzyme inducers on the hepatotoxicity of pyrrolizidine alkaloids in rats.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:2

    Topics: Animals; Enzyme Induction; Ethylestrenol; Female; Hepatectomy; Kidney; Liver; Lung; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Pregnenolone Carbonitrile; Prodigiosin; Pyrroles; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Spironolactone

1974
Phenytoin induction of the cyp2c37 gene is mediated by the constitutive androstane receptor.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:12

    Topics: Animals; Constitutive Androstane Receptor; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Liver; Male; Mice; Mice, Inbred C3H; Mice, Knockout; Phenobarbital; Phenytoin; Pregnane X Receptor; Pregnenolone Carbonitrile; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Transcription Factors

2006
Induction of the UDP-Glucuronosyltransferase 1A1 during the Perinatal Period Can Cause Neurodevelopmental Toxicity.
    Molecular pharmacology, 2016, Volume: 90, Issue:3

    Topics: Animals; Animals, Newborn; Brain; Carbamazepine; Cell Movement; Enzyme Induction; Female; Gene Expression Regulation, Developmental; Genes, Developmental; Glucuronosyltransferase; Humans; Mice, Inbred C57BL; Mice, Transgenic; Milk, Human; Neurodevelopmental Disorders; Phenytoin; Pregnancy; Pregnenolone Carbonitrile; Prenatal Exposure Delayed Effects; RNA, Messenger; Rotarod Performance Test; Thyroxine

2016