phenytoin has been researched along with pilocarpine in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (25.81) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 8 (25.81) | 29.6817 |
| 2010's | 12 (38.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Corcia, RM; Gay, PE; Lamon, S; Leaf, RC; Wnek, DJ | 1 |
| Andrews, JS; Bortolotto, ZA; Bressler, K; Calderazzo-Filho, LS; Cavalheiro, EA; Löschmann, PA; Turski, L | 1 |
| Krip, G; Vazquez, AJ | 1 |
| Podos, SM | 1 |
| Hatch, RC | 1 |
| Cross, EG; De Young, G | 1 |
| George, B; Kulkarni, SK | 1 |
| DeLorenzo, RJ; Jafari, N; Morris, TA; Rice, AC; Vasconcelos, O | 1 |
| Esmaeil, N; Jones, DM; Macdonald, RL; Maren, S | 1 |
| ZABLOCKA, B | 1 |
| SANDBERG, F | 1 |
| Anderson, NJ; Slough, S; Watson, WP | 1 |
| Bogo, MR; Bonan, CD; Bruno, AN; Cognato, Gde P; da Silva, RS; Sarkis, JJ | 1 |
| Beck, H; Schaub, C; Uebachs, M | 1 |
| Bankstahl, JP; Löscher, W | 1 |
| Cunha, AO; dos Santos, WF; Liberato, JL; Mortari, MR | 1 |
| Alcantara-Gonzalez, D; Cuellar-Herrera, M; Neri-Bazan, L; Peña, F; Rocha, L | 1 |
| Tawfik, MK | 1 |
| Kaminski, RM; Leclercq, K | 1 |
| Chen, B; Chen, S; Chen, Z; Fang, Z; Li, Z; Ni, G; Ning, Y; Qin, J; Wu, C; Zhou, J; Zhou, L | 1 |
| Baldwin, R; Lumley, L; Niquet, J; Norman, K; Suchomelova, L; Wasterlain, CG | 1 |
| Fu, J; Gao, F; Gao, Y; Li, Y; Meng, F; Yang, C | 1 |
| Beck, RCR; Cardoso, AM; Coradini, K; de Oliveira, CV; de Oliveira, EG; Guterres, SS; Oliveira, MS; Paese, K; Pohlmann, AR | 1 |
| Jand, A; Mousavi-Hasanzadeh, M; Palizvan, MR; Rezaeian-Varmaziar, H; Shafaat, O | 1 |
2 review(s) available for phenytoin and pilocarpine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Glaucoma.
Topics: Acid-Base Equilibrium; Animals; Contact Lenses, Hydrophilic; Delayed-Action Preparations; Glaucoma; Humans; Hydrogen-Ion Concentration; Hydroxydopamines; Intraocular Pressure; Optic Nerve; Optic Neuritis; Phenytoin; Pilocarpine; Rabbits; Sodium | 1973 |
29 other study(ies) available for phenytoin and pilocarpine
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Chlordiazepoxide and diazepam induced mouse killing by rats.
Topics: Aggression; Amphetamine; Animals; Behavior, Animal; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Humans; Male; Mice; Parasympatholytics; Pentobarbital; Phenytoin; Pilocarpine; Predatory Behavior; Rats | 1975 |
Substantia nigra regulates action of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroencephalography; Ethosuximide; Male; Microinjections; Midazolam; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra; Trimethadione | 1990 |
Effects of diphenylhydantoin and cholinergic agents on the neuronally isolated cerebral cortex.
Topics: Animals; Atropine; Cats; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Parasympathomimetics; Phenytoin; Physostigmine; Pilocarpine; Scopolamine; Seizures; Synaptic Transmission; Trimethadione | 1971 |
Effect of drugs on catnip (Nepeta cataria)-induced pleasure behavior in cats.
Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Cats; Chlorpheniramine; Chlorpromazine; Drug Synergism; Female; Hexamethonium Compounds; Histidine; Lactones; Magnoliopsida; Male; Mecamylamine; Methysergide; Morphine; Neostigmine; Phenytoin; Physostigmine; Pilocarpine; Plant Extracts; Propranolol; Pyrans; Salivation; Serotonin; Sexual Behavior, Animal | 1972 |
Stramonium psychodelia.
Topics: Adolescent; Adult; Datura stramonium; Diazepam; Hallucinogens; Humans; Male; Phenytoin; Pilocarpine; Plants, Medicinal; Plants, Toxic; Poisoning; Substance-Related Disorders | 1969 |
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid | 1996 |
Persistent increased DNA-binding and expression of serum response factor occur with epilepsy-associated long-term plasticity changes.
Topics: Animals; Brain; Cell Nucleus; Cerebellum; Cerebral Cortex; Dizocilpine Maleate; DNA-Binding Proteins; Electroshock; Gene Expression Regulation; Hippocampus; Humans; Male; Neuronal Plasticity; Nuclear Proteins; Oligodeoxyribonucleotides; Organ Specificity; Phenytoin; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Serum Response Factor; Status Epilepticus; Transcription Factors | 1999 |
Characterization of pharmacoresistance to benzodiazepines in the rat Li-pilocarpine model of status epilepticus.
Topics: Animals; Anticonvulsants; Benzodiazepines; Chi-Square Distribution; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; Electroencephalography; Lithium Chloride; Male; Muscarinic Agonists; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Time Factors | 2002 |
Effects of autonomic agents, alone and in combination with antiepileptic drugs, on electroshock seizures in rats.
Topics: Animals; Anticonvulsants; Atropine; Autonomic Agents; Electroshock; Methacholine Compounds; Neostigmine; Phenobarbital; Phenytoin; Physostigmine; Pilocarpine; Rats; Seizures | 1963 |
A comparative study of the anticonvulsant effect of the N-substituted 5,5-diallylbarbiturates and 5,5-diphenylhydantoins.
Topics: Anticonvulsants; Barbiturates; Humans; Hydantoins; Phenytoin; Pilocarpine; Seizures | 1951 |
In vivo characterisation of the small-conductance KCa (SK) channel activator 1-ethyl-2-benzimidazolinone (1-EBIO) as a potential anticonvulsant.
Topics: Animals; Anticonvulsants; Benzimidazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Levetiracetam; Male; Mice; Motor Activity; Pentylenetetrazole; Phenytoin; Pilocarpine; Piracetam; Seizures; Sensory Thresholds; Small-Conductance Calcium-Activated Potassium Channels | 2006 |
Antiepileptic drugs prevent changes induced by pilocarpine model of epilepsy in brain ecto-nucleotidases.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Anticonvulsants; Brain; Carbamazepine; Cerebral Cortex; Epilepsy; Hippocampus; Male; Muscarinic Agonists; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Synaptosomes; Valproic Acid | 2007 |
Diminished response of CA1 neurons to antiepileptic drugs in chronic epilepsy.
Topics: Action Potentials; Animals; Anticonvulsants; Carbamazepine; Chronic Disease; Dentate Gyrus; Disease Models, Animal; Drug Resistance; Epilepsy; Hippocampus; Humans; Neurons; Patch-Clamp Techniques; Phenytoin; Pilocarpine; Pyramidal Cells; Rats; Sodium Channels; Synaptic Transmission | 2007 |
Resistance to antiepileptic drugs and expression of P-glycoprotein in two rat models of status epilepticus.
Topics: Amygdala; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; Diazepam; Disease Models, Animal; Drug Resistance; Electric Stimulation; Endothelium, Vascular; Female; Gene Expression Regulation; Genes, MDR; Hippocampus; Phenobarbital; Phenytoin; Pilocarpine; Quinolines; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2008 |
Neuroprotective effects of diazepam, carbamazepine, phenytoin and ketamine after pilocarpine-induced status epilepticus.
Topics: Animals; Anticonvulsants; Carbamazepine; Dentate Gyrus; Diazepam; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Hippocampus; Ketamine; Male; Maze Learning; Neuroprotective Agents; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2009 |
Antiepileptic drugs combined with high-frequency electrical stimulation in the ventral hippocampus modify pilocarpine-induced status epilepticus in rats.
Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Lithium Chloride; Male; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Synaptic Transmission | 2010 |
Coenzyme Q10 enhances the anticonvulsant effect of phenytoin in pilocarpine-induced seizures in rats and ameliorates phenytoin-induced cognitive impairment and oxidative stress.
Topics: Analysis of Variance; Animals; Anticonvulsants; Avoidance Learning; Catalase; Cognition Disorders; Disease Models, Animal; Drug Synergism; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Phenytoin; Pilocarpine; Psychomotor Performance; Rats; Rats, Wistar; Reaction Time; Severity of Illness Index; Status Epilepticus; Superoxide Dismutase; Ubiquinone | 2011 |
Status epilepticus induction has prolonged effects on the efficacy of antiepileptic drugs in the 6-Hz seizure model.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Levetiracetam; Male; Mice; Phenytoin; Pilocarpine; Piracetam; Seizures; Status Epilepticus; Treatment Outcome | 2015 |
Pluronic P85-coated poly(butylcyanoacrylate) nanoparticles overcome phenytoin resistance in P-glycoprotein overexpressing rats with lithium-pilocarpine-induced chronic temporal lobe epilepsy.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chronic Disease; Disease Models, Animal; Drug Resistance; Enbucrilate; Epilepsy, Temporal Lobe; Female; Hippocampus; Lithium; Nanoparticles; Phenytoin; Pilocarpine; Poloxalene; Rats, Sprague-Dawley; Reproducibility of Results; Seizures; Tissue Distribution | 2016 |
Simultaneous triple therapy for the treatment of status epilepticus.
Topics: Animals; Anticonvulsants; Brain Waves; Combined Modality Therapy; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Male; Maze Learning; Midazolam; Neurons; Phenytoin; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Treatment Outcome; Valproic Acid | 2017 |
The Sphingosine 1-Phosphate Analogue FTY720 Alleviates Seizure-induced Overexpression of P-Glycoprotein in Rat Hippocampus.
Topics: Anilides; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclooxygenase 2; Disease Models, Animal; Drug Resistant Epilepsy; Fingolimod Hydrochloride; Hippocampus; Humans; Immunosuppressive Agents; Injections, Intraperitoneal; Lysophospholipids; Male; Organophosphonates; Phenytoin; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sphingosine; Sphingosine-1-Phosphate Receptors; Up-Regulation | 2018 |
Reconstituted spray-dried phenytoin-loaded nanocapsules improve the in vivo phenytoin anticonvulsant effect and the survival time in mice.
Topics: Animals; Anticonvulsants; Chitosan; Desiccation; Drug Compounding; Drug Liberation; Female; Male; Mice, Inbred C57BL; Nanocapsules; Phenytoin; Pilocarpine; Polysaccharides; Powders; Seizures | 2018 |
The effect of co-administration of pentylenetetrazole with pilocarpine: New modified PTZ models of kindling and seizure.
Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Drug Resistance; Epilepsy; Kindling, Neurologic; Male; Miotics; Pentylenetetrazole; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Seizures; Valproic Acid | 2019 |