Compounds > phenytoin

phenytoin and phenylpiperazine

phenytoin has been researched along with phenylpiperazine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Filipek, B; Handzlik, J; Kieć-Kononowicz, K; Kubacka, M; Maciag, D; Mogilski, S; Stadnicka, K1
Görnemann, T; Handzlik, J; Jähnichen, S; Kieć-Kononowicz, K; Pertz, HH1
Kamiński, K; Obniska, J; Rzepka, S1
Bajda, M; Bednarski, M; Dybała, M; Filipek, B; Handzlik, J; Kieć-Kononowicz, K; Maciąg, D; Malawska, B; Zygmunt, M1

Other Studies

4 other study(ies) available for phenytoin and phenylpiperazine

ArticleYear
Synthesis, alpha 1-adrenoceptor antagonist activity, and SAR study of novel arylpiperazine derivatives of phenytoin.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Phenytoin; Piperazines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship

2008
Search for influence of spatial properties on affinity at α1-adrenoceptor subtypes for phenylpiperazine derivatives of phenytoin.
    Bioorganic & medicinal chemistry letters, 2010, Oct-15, Volume: 20, Issue:20

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Guinea Pigs; Models, Molecular; Phenytoin; Piperazines; Rats; Receptors, Adrenergic, alpha-1

2010
Synthesis and anticonvulsant activity of new 1-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyrrolidine-2,5-diones.
    Bioorganic & medicinal chemistry letters, 2011, Oct-01, Volume: 21, Issue:19

    Topics: Administration, Oral; Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Electroshock; Ethosuximide; Injections, Intraperitoneal; Mice; Molecular Structure; Motor Activity; Pentylenetetrazole; Phenytoin; Piperazines; Rats; Seizures; Structure-Activity Relationship; Succinimides; Time Factors

2011
Antiarrhythmic properties of phenylpiperazine derivatives of phenytoin with α₁-adrenoceptor affinities.
    Bioorganic & medicinal chemistry, 2012, Apr-01, Volume: 20, Issue:7

    Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Heart Rate; Imidazolidines; Male; Phenytoin; Piperazines; Protein Binding; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Structure-Activity Relationship

2012