phenytoin and phenylbutazone

phenytoin has been researched along with phenylbutazone in 95 studies

Research

Studies (95)

TimeframeStudies, this research(%)All Research%
pre-199079 (83.16)18.7374
1990's2 (2.11)18.2507
2000's5 (5.26)29.6817
2010's9 (9.47)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Afzelius, L; Andersson, TB; Baroni, M; Cruciani, G; Karlén, A; Masimirembwa, CM; Mecucci, S; Zamora, I1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Bolt, DJ; Cooper, BS; Hawk, HW1
Harner, RS; McDowell, AE; Pardue, HL1
Cooper, BS; Hawk, HW1
Fröscher, W; Gugler, R; Schulz, HU1
Christensen, LK; Hansen, JM1
d'Athis, P; Lecomte, M; Tillement, JP; Zini, R1
Belpaire, FM; Bogaert, MG; van Peer, AP4
Belpaire, F; Bogaert, M; Van Peer, A1
Hausmann, K; Sachtleben, P; Skrandies, G2
Gross, MA; Yunis, AA1
Bircher, J; Preisig, R1
Azarnoff, DL; Shoeman, DW1
Olive, G1
Davies, RO; Gagnon, MA; McLean, WM; Ruedy, J; Thompson, WG; Vitti, TG; Wilson, TW1
Kubow, S; Wells, PG1
Bornuz, F; Hadnagy, C; Macavei, I; Marinca, E; Sass, G1
Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y1
Bixler, TJ; Del Rio, AE; Rudman, D1
Dayton, PG; Perel, JM1
Passananti, GT; Vessell, ES1
Jatlow, P1
Kutt, H; Penry, JK1
McQueen, EG1
Cucinell, SA; Dayton, PG; Perel, JM; Weiss, M1
Hansen, JM; Hansen, OE; Kristensen, M; Lund, V1
Lucas, BG1
Vesell, ES2
Evans, DA1
Friis, T; Hansen, MJ; Kolendorf, K; Siersbaek-Nielsen, K1
Hahn, I; Krieglstein, G; Krieglstein, J; Tschentscher, K1
Greengard, P; Quinn, GP; Reid, MB1
Cockrill, BL; Platt, DS1
Garattini, S; Szalay, KS; Szeberenyi, S1
Creger, WP; Potolsky, A1
Eipe, J1
Schulz, KH1
Fishbein, L; Flamm, WG1
Breckenridge, A1
Gajewska, M1
Andersen, SA; Andreasen, PB; Froland, A; Hauge, M; Skovsted, L1
Andreasen, F1
Kurata, D; Wilkinson, GR1
Ganzoni, AM; Muller, C1
Fanuele, G; Rossi, U1
Altland, K; Goedee, HW1
Ito, S1
Aly, FW1
Jähnchen, E; Levy, G1
Bianchi, C; Bonardi, G1
Abrams, WB; Reich, S; Solomon, HM; Spirt, N1
Bhalla, TN; Bhargava, KP; Kohli, RP; Sinha, JN1
Jacobsen, CD1
Lunde, KM1
Flessa, HC; Sigell, LT1
Kadokawa, T; Nakamura, H; Nakamura, K; Nakatsuji, K1
Calhoun, FJ; Schrogie, JJ; Tolson, WW1
Burba, JV1
Dayton, PG; Sanders, JE1
Perucca, E1
Wollina, U1
Goldberg, DM1
Greim, H1
Belpaire, FM; Bogaert, MG; Rosseel, MT; Van Peer, AP1
Chou, D; Holtzman, JL; Leppik, IE; Polnaszek, CF; Yost, Y1
Knipping, W1
Coker, ST; Davidson, PP; Grissette, DE; Stewart, SE; Williams, BB1
Horbach, GJ; Witkamp, RF; Zweers-Zeilmaker, WM1
Gibson, GG; Goldfarb, PS; Gray, TJ; Ogg, MS; Tarbit, M; Williams, JM1
Asakawa, N; Ishihama, Y; Miwa, T1
BURNS, JJ; CONNEY, AH; CUCINELL, SA; KOSTER, R1
HARVEY, P1
DOAN, CA1
BURNS, JJ1

Reviews

19 review(s) available for phenytoin and phenylbutazone

ArticleYear
[Valproic acid in the treatment of epilepsy with special emphasis on serum level determination (author's transl)].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1978, Volume: 46, Issue:6

    Topics: Blood Platelets; Drug Interactions; Electroencephalography; Epilepsy; Fatigue; Half-Life; Humans; Phenobarbital; Phenylbutazone; Phenytoin; Protein Binding; Salicylates; Sulfadimethoxine; Valerates; Valproic Acid

1978
Drug interactions with oral sulphonylurea hypoglycaemic drugs.
    Drugs, 1977, Volume: 13, Issue:1

    Topics: Allopurinol; Analgesics; Anticoagulants; Chloramphenicol; Chlorpropamide; Disulfiram; Drug Interactions; Ethanol; Glyburide; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Kinetics; Monoamine Oxidase Inhibitors; Novobiocin; Phenylbutazone; Phenytoin; Probenecid; Propranolol; Rifampin; Sulfonamides; Sulfonylurea Compounds; Tolbutamide

1977
Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats.
    Journal of pharmacokinetics and biopharmaceutics, 1985, Volume: 13, Issue:5

    Topics: Animals; Antipyrine; Barbiturates; Biological Availability; Chlorpromazine; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Pentazocine; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Propranolol; Quinidine; Rats; Species Specificity; Tissue Distribution; Tolbutamide; Valproic Acid; Warfarin

1985
Physiological and physicochemical bases of drug interactions in man.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chemistry, Physical; Chromatography, Thin Layer; Deuterium; Dextrans; Dicumarol; Dogs; Drug Antagonism; Drug Synergism; Humans; Kinetics; Male; Metabolism; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Probenecid; Protein Binding; Receptors, Drug; Salicylates; Stereoisomerism; Sulfinpyrazone; Sulfoxides; Thiopental

1971
Utility of clinical chemical determinations of drug concentrations in biological fluids.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Adult; Allopurinol; Antipyrine; Ataxia; Chemistry, Clinical; Chromatography, Gas; Coffee; Desipramine; Dicumarol; Drug Antagonism; Drug Synergism; Ethanol; Female; Fluorometry; Half-Life; Humans; Iatrogenic Disease; Male; Mental Disorders; Metabolism; Methods; Middle Aged; Morphine; Nortriptyline; Nystagmus, Pathologic; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Smoking; Spectrophotometry; Twins; Ultraviolet Rays

1971
Usefulness of blood levels of antiepileptic drugs.
    Archives of neurology, 1974, Volume: 31, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines

1974
Recent progress in pharmacogenetics.
    Advances in pharmacology, 1969, Volume: 7

    Topics: Adult; Aged; Alcohol Oxidoreductases; Antipyrine; Asian People; Child, Preschool; Cholinesterases; Cyanides; Dicumarol; Diseases in Twins; Drug Hypersensitivity; Erythrocytes; Favism; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Isoniazid; Liver; Male; Metabolism, Inborn Errors; Middle Aged; Pharmacogenetics; Phenylbutazone; Phenylthiourea; Phenytoin; Pregnancy; Primaquine; Twins; Warfarin

1969
Recent progress in pharmacogenetics.
    Advances in pharmacology and chemotherapy, 1969, Volume: 7

    Topics: Adult; Antipyrine; Cyanides; Dicumarol; Erythrocytes; Ethnicity; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Isoniazid; Male; Middle Aged; Mutation; Pharmacogenetics; Phenylbutazone; Phenylthiourea; Phenytoin; Pregnancy; Racial Groups; Taste; Twins

1969
Drugs affecting therapy with anticoagulants.
    The Medical clinics of North America, 1972, Volume: 56, Issue:1

    Topics: Anticoagulants; Chloramphenicol; Clofibrate; Contraceptives, Oral; Coumarins; Diuretics; Drug Interactions; Drug Synergism; Drug-Related Side Effects and Adverse Reactions; Estrogens; Ethanol; Heparin; Humans; Hypnotics and Sedatives; Phenylbutazone; Phenytoin; Salicylates; Thyroxine; Tolbutamide; Vitamin K

1972
Potential environmental chemical hazards. I. Drugs.
    The Science of the total environment, 1972, Volume: 1, Issue:1

    Topics: Abnormalities, Drug-Induced; Alkylating Agents; Analgesics; Animals; Aspirin; Carcinogens; Drug-Related Side Effects and Adverse Reactions; Hexachlorophene; Humans; Hydrazines; Isoniazid; Phenacetin; Phenylbutazone; Phenytoin; Procarbazine; Salicylates

1972
Anticonvulsant pharmacokinetics.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:1

    Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Drug Interactions; Endoplasmic Reticulum; Humans; Hydrocortisone; Kinetics; Nucleoproteins; Phenobarbital; Phenylbutazone; Phenytoin; Protein Binding; Salicylates

1974
[Acquired aplastic anemia, with special consideration of complications and prognosis].
    Schweizerische medizinische Wochenschrift, 1970, Mar-07, Volume: 100, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anemia, Aplastic; Blood Cell Count; Carbutamide; Chloramphenicol; Chlordiazepoxide; Female; Hemoglobins; Hemorrhage; Humans; Infections; Male; Middle Aged; Nitrofurans; Phenylbutazone; Phenytoin; Prognosis

1970
[Genetically dependent variability of drug effects].
    Medizinische Klinik, 1970, Aug-28, Volume: 65, Issue:35

    Topics: Anemia, Hemolytic; Anesthesia, General; Anesthetics; Animals; Antipyrine; Apnea; Atropine; Body Temperature; Coumarins; Cyanosis; Deficiency Diseases; Dexamethasone; Dogs; Drug Tolerance; Enzymes; Female; Glucosephosphate Dehydrogenase; Humans; Intraocular Pressure; Isonicotinic Acids; Male; Meperidine; Mice; Oxyphenbutazone; Pharmacogenetics; Phenacetin; Phenylbutazone; Phenytoin; Proteins; Rabbits; Rats; Succinylcholine

1970
[Recent data on thyroxine-binding protein].
    Saishin igaku. Modern medicine, 1967, Volume: 22, Issue:7

    Topics: Androgens; Animals; Anticoagulants; Barbiturates; Bilirubin; Carbon Dioxide; Chemical Phenomena; Chemistry, Physical; Diuretics; Estrogens; Glucocorticoids; Humans; Novobiocin; Penicillins; Phenylbutazone; Phenytoin; Salicylates; Thyroid Diseases; Thyroxine; Thyroxine-Binding Proteins; Tolbutamide

1967
[Competitive mechanisms in hormone transport].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1968, Volume: 74

    Topics: Antithyroid Agents; Biological Transport; Blood Proteins; Female; Humans; Male; Models, Biological; Pharmaceutical Vehicles; Phenylbutazone; Phenytoin; Thyroid Hormones; Thyroxine-Binding Proteins

1968
Dose-dependent pharmacokinetics: emphasis on phase I metabolism.
    Drug metabolism reviews, 1983, Volume: 14, Issue:3

    Topics: 2,4,5-Trichlorophenoxyacetic Acid; Adolescent; Adult; Age Factors; Aged; Animals; Antineoplastic Agents; Child; Child, Preschool; Coumarins; Dioxanes; Dose-Response Relationship, Drug; Humans; Infant; Infant, Newborn; Kinetics; Mathematics; Middle Aged; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Tissue Distribution

1983
The expanding role of microsomal enzyme induction, and its implications for clinical chemistry.
    Clinical chemistry, 1980, Volume: 26, Issue:6

    Topics: Acetaminophen; Alcoholism; Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Electron Transport; Energy Intake; Enzyme Induction; Epilepsy; Female; Humans; Male; Microsomes, Liver; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Smoking; Tolbutamide; Warfarin

1980
[Enzyme induction in the liver changes drug activity].
    Medizinische Klinik, 1980, Sep-26, Volume: 75, Issue:20

    Topics: Animals; Barbiturates; Carbamazepine; Chlorpromazine; Drug Interactions; Enzyme Induction; Glutethimide; Humans; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Rifampin; Time Factors

1980
IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY.
    The American journal of medicine, 1964, Volume: 37

    Topics: Animals; Benzopyrenes; Cyclizine; Dicumarol; Diphenhydramine; Dogs; Drug Therapy; Enzyme Induction; Enzymes; Glutethimide; Hexobarbital; Liver; Meprobamate; Metabolism; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Probenecid; Rats; Research; Tolbutamide; Toxicology; Zoxazolamine

1964

Trials

1 trial(s) available for phenytoin and phenylbutazone

ArticleYear
[Therapy of epilepsy in childhood. Clinical testing of a new combination of drugs].
    La Pediatria, 1969, Volume: 77, Issue:1

    Topics: Barbiturates; Caffeine; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy, Temporal Lobe; Female; Humans; Infant; Male; Phenylbutazone; Phenytoin

1969

Other Studies

75 other study(ies) available for phenytoin and phenylbutazone

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Conformer- and alignment-independent model for predicting structurally diverse competitive CYP2C9 inhibitors.
    Journal of medicinal chemistry, 2004, Feb-12, Volume: 47, Issue:4

    Topics: Amino Acids; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 CYP2C9; Enzyme Inhibitors; Models, Molecular; Molecular Conformation; Molecular Structure; Quantitative Structure-Activity Relationship

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
The effect of microsomal enzyme inducing drugs on reproductive function in the ewe.
    Theriogenology, 1975, Volume: 4, Issue:6

    Topics: Animals; Corpus Luteum; Enzyme Induction; Estrus; Female; Liver; Luteinizing Hormone; Microsomes, Liver; Organ Size; Phenobarbital; Phenylbutazone; Phenytoin; Piperazines; Pregnancy; Pregnenolone; Progesterone; Reproduction; Sheep; Sleep

1975
Application of a vidicon spectrometer for simultaneous multicomponent drug determinations.
    Clinical chemistry, 1976, Volume: 22, Issue:11

    Topics: Acetaminophen; Aminophylline; Barbiturates; Computers; Humans; Pharmaceutical Preparations; Phenobarbital; Phenylbutazone; Phenytoin; Procainamide; Regression Analysis; Salicylamides; Secobarbital; Spectrophotometry, Ultraviolet; Time Factors

1976
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to man, 1977, Volume: 13

    Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; Ethionamide; Female; Humans; Hycanthone; Male; Metronidazole; Neoplasms; Neoplasms, Experimental; Oxazepam; Oxymetholone; Oxyphenbutazone; Oxyquinoline; Phenacetin; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Pyrimethamine; Risk

1977
Effect of liver microsome enzyme-inducing drugs on blood serum pentobarbital clearance and sleep time in sheep and rabbits.
    American journal of veterinary research, 1978, Volume: 39, Issue:4

    Topics: Animals; Microsomes, Liver; Pentobarbital; Phenobarbital; Phenylbutazone; Phenytoin; Piperazines; Rabbits; Sheep; Sleep; Time Factors

1978
Phenytoin binding to human albumin.
    European journal of drug metabolism and pharmacokinetics, 1979, Volume: 4, Issue:1

    Topics: Anilino Naphthalenesulfonates; Fatty Acids, Nonesterified; Humans; Imipramine; Palmitic Acids; Phenylbutazone; Phenytoin; Protein Binding; Serum Albumin; Warfarin

1979
In vitro hepatic oxidative metabolism of antipyrine, phenytoin and phenylbutazone in rabbits with experimental renal failure.
    Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 234, Issue:2

    Topics: Animals; Antipyrine; In Vitro Techniques; Kidney Failure, Chronic; Kinetics; Liver; Oxidation-Reduction; Phenylbutazone; Phenytoin; Rabbits

1978
Distribution of phenytoin and phenylbutazone in normal and uraemic rabbits.
    Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 234, Issue:2

    Topics: Animals; Phenylbutazone; Phenytoin; Rabbits; Tissue Distribution; Uremia

1978
Pharmacokinetics of drugs in rabbits with experimental acute renal failure.
    Pharmacology, 1978, Volume: 17, Issue:6

    Topics: Acute Kidney Injury; Animals; Antipyrine; Blood Proteins; Female; Half-Life; Phenylbutazone; Phenytoin; Protein Binding; Rabbits; Uranyl Nitrate; Urea

1978
Clinicopathological Conference. Diagnostic difficulties in a case of polypharmacy. Demonstrated at the Royal College of Physicians of London.
    British medical journal, 1977, Jan-22, Volume: 1, Issue:6055

    Topics: Acute Kidney Injury; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Hepatitis, Viral, Human; Humans; Liver Diseases; Male; Middle Aged; Phenylbutazone; Phenytoin

1977
[Current aspects of iatrogenic lesions of the bone marrow].
    Minerva medica, 1976, Nov-14, Volume: 67, Issue:55

    Topics: Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow Diseases; Chloramphenicol; Drug-Related Side Effects and Adverse Reactions; Gold; Humans; Oxyphenbutazone; Phenylbutazone; Phenytoin; Sulfonamides

1976
Drug-induced inhibition of myeloid colony growth: protective effect of colony-stimulating factor.
    The Journal of laboratory and clinical medicine, 1975, Volume: 86, Issue:3

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Chloramphenicol; Chlorpromazine; Clone Cells; Dose-Response Relationship, Drug; In Vitro Techniques; Leukopenia; Mice; Phenylbutazone; Phenytoin; Tetracycline; Thiamphenicol

1975
[Editorial: To measure or not to measure--that is the question. Problems of measuring blood levels of drugs].
    Schweizerische medizinische Wochenschrift, 1975, Jul-26, Volume: 105, Issue:30

    Topics: Digitalis Glycosides; Dose-Response Relationship, Drug; Humans; Lithium; Pharmaceutical Preparations; Phenobarbital; Phenylbutazone; Phenytoin; Salicylates

1975
Diphenylhydantoin potency and plasma protein binding.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 195, Issue:1

    Topics: Administration, Oral; Animals; Blood Proteins; Drug Synergism; Electroshock; Male; Phenylbutazone; Phenytoin; Protein Binding; Rats; Seizures; Time Factors

1975
[Interest in the determination of drugs and their metabolites in clinical pharmacology and therapeutics].
    Annales de biologie clinique, 1975, Volume: 33, Issue:3

    Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antidepressive Agents, Tricyclic; Digitalis Glycosides; Dose-Response Relationship, Drug; Lithium; Pharmaceutical Preparations; Phenobarbital; Phenylbutazone; Phenytoin; Theophylline

1975
Letter: Drug bioavailability.
    Canadian Medical Association journal, 1976, Jul-17, Volume: 115, Issue:2

    Topics: Biological Availability; Biopharmaceutics; Digoxin; Phenylbutazone; Phenytoin; Warfarin

1976
In vitro bioactivation of phenytoin to a reactive free radical intermediate by prostaglandin synthetase, horseradish peroxidase, and thyroid peroxidase.
    Molecular pharmacology, 1989, Volume: 35, Issue:4

    Topics: Animals; Biotransformation; Electron Spin Resonance Spectroscopy; Free Radicals; Horseradish Peroxidase; Iodide Peroxidase; Lung; Male; Microsomes; Microsomes, Liver; Oxygen Consumption; Peroxidases; Phenylbutazone; Phenytoin; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep

1989
[Bone marrow-damaging effect of various drugs].
    Zeitschrift fur arztliche Fortbildung, 1985, Volume: 79, Issue:9

    Topics: Antitubercular Agents; Bone Marrow; Chloramphenicol; Drug Hypersensitivity; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Hematopoiesis; Humans; Neutropenia; Nitrofurantoin; Pancytopenia; Penicillins; Phenylbutazone; Phenytoin; Red-Cell Aplasia, Pure; Tetracycline; Thrombocytopenia

1985
Effect of free fatty acids on binding of drugs by bovine serum albumin, by human serum albumin and by rabbit serum.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 176, Issue:2

    Topics: Animals; Binding Sites; Blood; Caprylates; Dialysis; Dicumarol; Fatty Acids, Nonesterified; Humans; Phenylbutazone; Phenytoin; Protein Binding; Rabbits; Salicylates; Serum Albumin; Serum Albumin, Bovine; Sulfadiazine; Sulfobromophthalein; Thiopental

1971
Ultraviolet spectrophotometric analysis of barbiturates: evaluation of potential interferences.
    American journal of clinical pathology, 1973, Volume: 59, Issue:2

    Topics: Acetaminophen; Barbiturates; Chlorothiazide; Chlorpropamide; Dicumarol; Humans; Methods; Nicotinic Acids; Oxyphenbutazone; Phenacetin; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Salicylates; Spectrophotometry, Ultraviolet; Sulfamethoxazole; Sulfinpyrazone; Sulfisoxazole; Theobromine; Theophylline; Warfarin

1973
Drug displacement from protein-binding and redistributional interactions.
    Progress in biochemical pharmacology, 1974, Volume: 9

    Topics: Animals; Blood Proteins; Carboxylic Acids; Clofibrate; DDT; Dieldrin; Guanidines; Hexachlorocyclohexane; Humans; Kinetics; Oxyphenbutazone; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Protein Binding; Rats; Sheep; Ultrafiltration; Warfarin

1974
Dose-dependence of drug plasma level decline in dogs.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:2

    Topics: Acetates; Animals; Barbiturates; Blood Proteins; Chlorine; Chromatography, Thin Layer; Dicumarol; Dogs; Kinetics; Liver; Muscles; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Probenecid; Receptors, Drug; Vitamin K

1967
Sources of error in the determination of phenytoin (Dilantin) by Svensmark & Kristensen's method.
    Acta neurologica Scandinavica, 1967, Volume: 43, Issue:4

    Topics: Dicumarol; Epilepsy; Ethosuximide; Humans; Methods; Phenylbutazone; Phenytoin; Spectrophotometry

1967
"Dilantin" overdosage.
    The Medical journal of Australia, 1968, Oct-12, Volume: 2, Issue:15

    Topics: Aminosalicylic Acids; Anticonvulsants; Calcium; Dicumarol; Disulfiram; Drug Synergism; Drug Tolerance; Humans; Isoniazid; Lactose; Phenylbutazone; Phenytoin; Sulfaphenazole; Sulfates; Thiazines

1968
The hydroxylation of drugs- a pharmacogenetic problem?
    Proceedings of the Royal Society of Medicine, 1970, Volume: 63, Issue:2

    Topics: Antipyrine; Dicumarol; Endoplasmic Reticulum; Liver; Mixed Function Oxygenases; Nortriptyline; Pharmacogenetics; Phenylbutazone; Phenytoin

1970
Evaluation of thyroid status with "effective thyroxine ratio" (E.T.R.).
    Acta endocrinologica, 1974, Volume: 77, Issue:2

    Topics: Adolescent; Adult; Aged; Aspirin; Depression, Chemical; Estrogens; Evaluation Studies as Topic; Female; Humans; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Male; Menopause; Middle Aged; Phenylbutazone; Phenytoin; Pregnancy; Stimulation, Chemical; Sulfadiazine; Sulfathiazoles; Thyroid Function Tests; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine

1974
[Present aspects of bone marrow lesions due to drugs (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1974, Sep-20, Volume: 116, Issue:38

    Topics: Anemia, Aplastic; Bone Marrow Diseases; Chloramphenicol; Drug-Related Side Effects and Adverse Reactions; Germany, West; Gold; Humans; Oxyphenbutazone; Phenylbutazone; Phenytoin; Sulfonamides; Sweden; United States

1974
Distribution of chlorpromazine in a simplified blood influenced by various drugs.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 278, Issue:1

    Topics: Acetazolamide; Animals; Antidepressive Agents; Benzoates; Binding Sites; Binding, Competitive; Cattle; Chlorothiazide; Chlorpromazine; Coumarins; Deoxycholic Acid; Erythrocytes; Fatty Acids; Indomethacin; Phenylbutazone; Phenytoin; Probenecid; Protein Binding; Quinine; Salicylates; Serum Albumin, Bovine; Solubility; Sulfonamides; Suramin; Tetracycline; Thiopental

1973
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine

1966
Biochemical changes in rat liver in response to treatment with drugs and other agents. I. Effects of anticonvulsant, anti-inflammatory, hypocholesterolaemic and adrenergic beta-blocking agents.
    Biochemical pharmacology, 1969, Volume: 18, Issue:2

    Topics: Acetanilides; Aminopyrine; Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Anticonvulsants; Barbiturates; Body Weight; Butyrates; Cytochromes; Cytoplasm; Electron Transport; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Indomethacin; L-Lactate Dehydrogenase; Liver; Male; Microsomes; Organ Size; Oxidoreductases; Phenobarbital; Phenylbutazone; Phenytoin; Phosphogluconate Dehydrogenase; Propranolol; Proteins; Rats; Sympatholytics

1969
Removal of plasma metyrapone in rats submitted to previous pharmacological treatment.
    The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:3

    Topics: Animals; Diazepam; Female; Hydrocortisone; Liver; Meprobamate; Metyrapone; Nikethamide; Pentaerythritol Tetranitrate; Phenobarbital; Phenylbutazone; Phenytoin; Rats

1969
Radiation and drug therapies, and leukemia.
    Annual review of medicine, 1973, Volume: 24

    Topics: Antineoplastic Agents; Benzene; Bone Marrow Diseases; Chloramphenicol; Cyclophosphamide; Dose-Response Relationship, Radiation; Humans; Immunosuppressive Agents; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Radiation-Induced; Melphalan; Multiple Myeloma; Phenylbutazone; Phenytoin; Polycythemia Vera

1973
[Lymphocyte transformation test in drug hypersensitivity].
    Archiv fur dermatologische Forschung, 1972, Volume: 244

    Topics: Ampicillin; Drug Hypersensitivity; Exanthema; Humans; Immunologic Techniques; Lymphocyte Activation; Penicillin G; Penicillins; Phenylbutazone; Phenytoin; Stevens-Johnson Syndrome; Sulfanilamides; Trimethoprim

1972
Complexometric determination of various diazole derivatives with cupric picrate.
    Acta poloniae pharmaceutica, 1972, Volume: 29, Issue:4

    Topics: Aminopyrine; Antipyrine; Azoles; Copper; Histamine; Hydrogen-Ion Concentration; Imidazoles; Indicators and Reagents; Methods; Metronidazole; Phenylbutazone; Phenytoin; Picrates; Structure-Activity Relationship; Tolazoline

1972
Diphenylhydantoin half-life in man and its inhibition by phenylbutazone: the role of genetic factors.
    Acta medica Scandinavica, 1973, Volume: 193, Issue:6

    Topics: Adult; Carbon Isotopes; Female; Genetics, Medical; Half-Life; Humans; Male; Phenylbutazone; Phenytoin; Pregnancy; Time Factors; Twins

1973
Protein binding of drugs in plasma from patients with acute renal failure.
    Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:6

    Topics: Acute Kidney Injury; Aged; Aspirin; Blood Proteins; Female; Humans; In Vitro Techniques; Male; Middle Aged; Phenylbutazone; Phenytoin; Protein Binding; Salicylates; Serum Albumin; Sulfadiazine; Thiopental

1973
Erythrocyte uptake and plasma binding of diphenylhydantoin.
    Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:2

    Topics: Carbon Radioisotopes; Dialysis; Erythrocytes; Ethosuximide; Female; Hematocrit; Humans; Hydroxylation; Liver Cirrhosis; Male; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Protein Binding; Sulfamethoxypyridazine; Time Factors; Uremia

1974
Determination of phenylbutazone in plasma.
    Clinical chemistry, 1972, Volume: 18, Issue:9

    Topics: Animals; Injections, Intravenous; Male; Methods; Oxidation-Reduction; Phenobarbital; Phenylbutazone; Phenytoin; Potassium Permanganate; Rats; Salicylates; Spectrophotometry; Spectrum Analysis; Sulfadiazine; Time Factors; Ultraviolet Rays; Warfarin

1972
Pharmacological investigations of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370). 3. General pharmacological properties.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:1

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Barbiturates; Blood Glucose; Cardiovascular System; Codeine; Diuresis; Edema; Enzyme Induction; Female; Male; Mice; Nervous System; Pepsinogens; Phenylbutazone; Phenytoin; Pyrazoles; Rats; Terpenes; Uric Acid

1972
Non-equivalent preparations of the same drug.
    Drug and therapeutics bulletin, 1971, Aug-13, Volume: 9, Issue:17

    Topics: Chloramphenicol; Dosage Forms; Humans; Nitrofurantoin; Oxytetracycline; Pharmaceutical Preparations; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Tetracycline; Therapeutic Equivalency; Tolbutamide; Warfarin

1971
Interactions between digitoxin and other drugs in vitro and in vivo.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Binding Sites; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Clofibrate; Digitoxin; Digoxin; Drug Antagonism; Enzyme Induction; Erythrocytes; Humans; Microsomes, Liver; Phenobarbital; Phenylbutazone; Phenytoin; Protein Binding; Radioisotopes; Rubidium; Serum Albumin; Sulfadimethoxine; Tolbutamide; Tritium; Warfarin

1971
Aconitine-induced writhing: a method for assessment of analgesic activity.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Aconitum; Analgesics; Animals; Aspirin; Behavior, Animal; Chlorpromazine; Imipramine; Mephenesin; Methaqualone; Methods; Mice; Morphine; Phenoxybenzamine; Phenylbutazone; Phenytoin; Sodium Salicylate

1969
[Drug-induced anemias].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1970, Dec-15, Volume: 90, Issue:24

    Topics: Adrenal Cortex Hormones; Anemia; Barbiturates; Bone Marrow; Chloramphenicol; Chlorpromazine; Dihydroxyphenylalanine; Gastrointestinal Hemorrhage; Gold; Humans; Hypoglycemic Agents; Indomethacin; Isoniazid; Nitrofurantoin; Phenacetin; Phenylbutazone; Phenytoin; Quinidine; Quinine; Salicylates; Sulfonamides

1970
Plasma protein binding of diphenylhydantoin in man.
    Acta pharmacologica et toxicologica, 1971, Volume: 29 Suppl 3

    Topics: Adult; Aspirin; Bilirubin; Blood Proteins; Carbon Isotopes; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Hyperbilirubinemia; Infant, Newborn; Male; Phenylbutazone; Phenytoin; Protein Binding; Sulfisoxazole; Uremia

1971
Drug interactions with anticoagulants.
    JAMA, 1970, Dec-14, Volume: 214, Issue:11

    Topics: Acetaminophen; Animals; Anti-Bacterial Agents; Anticoagulants; Ascorbic Acid; Barbiturates; Blood Coagulation; Blood Coagulation Tests; Cardiac Glycosides; Chlordiazepoxide; Chlorothiazide; Contraceptives, Oral; Diazepam; Dogs; Drug Antagonism; Epinephrine; Ethchlorvynol; Glucagon; Haloperidol; Humans; Methylphenidate; Phenethylamines; Phenylbutazone; Phenytoin; Quinolines; Salicylates; Steroids; Substance-Related Disorders; Tetanus Toxoid; Tolbutamide; Xanthines

1970
Pharmacological studies of a new anti-inflammatory drug, 1-phenylsulfonyl-5,5-diphenylhydantoin (PC-796) in experimental animals. I. Anti-inflammatory, analgesic and anti-pyretic activity.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Aminopyrine; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Capillary Permeability; Carrageenan; Croton Oil; Depression, Chemical; Edema; Exudates and Transudates; Female; Guinea Pigs; Indomethacin; Inflammation; Male; Mefenamic Acid; Mercaptopurine; Mice; Phenylbutazone; Phenytoin; Pregnanes; Protein Denaturation; Rabbits; Radiation-Protective Agents; Rats; Sulfones; Yeast, Dried

1970
Effects of various drugs on the uterotropic response to mestranol and norethynodrel in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 136, Issue:1

    Topics: Aminosalicylic Acids; Animals; Chlorpromazine; Drug Synergism; Female; Imipramine; Mestranol; Norethynodrel; Organ Size; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Rats; Scopolamine; Tolbutamide; Uterus

1971
Influence of several drugs on the in vivo and in vitro activity of mammalian hepatic azo-reductase.
    Canadian journal of biochemistry, 1968, Volume: 46, Issue:4

    Topics: Animals; Caffeine; Guanethidine; Guinea Pigs; In Vitro Techniques; Iproniazid; Isoniazid; Liver; Nitrofurantoin; Oxidoreductases; Pentylenetetrazole; Phenobarbital; Phenylbutazone; Phenytoin; Rabbits; Rats; Sulfinpyrazone; Sulfonic Acids; Trimethadione

1968
In vitro hepatic oxidative metabolism of antipyrine, phenytoin and phenylbutazone in uraemic rabbits.
    The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:2

    Topics: Animals; Antipyrine; Female; In Vitro Techniques; Kinetics; Liver; Microsomes, Liver; Oxidation-Reduction; Phenylbutazone; Phenytoin; Rabbits; Uremia

1980
Free level monitoring of antiepileptic drugs. Clinical usefulness and case studies.
    Clinical pharmacokinetics, 1984, Volume: 9 Suppl 1

    Topics: Adult; Anticonvulsants; Blood Proteins; Carbamazepine; Drug Interactions; Female; Humans; Male; Phenylbutazone; Phenytoin; Protein Binding; Serum Albumin; Valproic Acid

1984
[Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1984, Mar-01, Volume: 39, Issue:5

    Topics: Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus Erythematosus, Systemic; Phenylbutazone; Phenytoin; Procainamide; Syndrome

1984
Distribution of antipyrine, phenylbutazone and phenytoin in experimental renal failure.
    Pharmacology, 1981, Volume: 22, Issue:2

    Topics: Acute Kidney Injury; Animals; Antipyrine; Blood Proteins; Female; Phenylbutazone; Phenytoin; Protein Binding; Rabbits; Tissue Distribution

1981
Binding of drugs in serum, blood cells and tissues of rabbits with experimental acute renal failure.
    Pharmacology, 1981, Volume: 22, Issue:2

    Topics: Acute Kidney Injury; Animals; Antipyrine; Blood Cells; Blood Proteins; Female; Phenylbutazone; Phenytoin; Protein Binding; Rabbits; Tissue Distribution

1981
Application of spin labeling to drug assays. II. Determination of the binding of [14C]-phenytoin and spin-labeled phenytoins to albumin and human serum.
    Molecular pharmacology, 1981, Volume: 20, Issue:3

    Topics: Blood Proteins; Dialysis; Humans; Kinetics; Phenylbutazone; Phenytoin; Protein Binding; Salicylates; Serum Albumin; Spin Labels

1981
[Problems of evaluating rare adverse drug reactions using as an example agranulocytosis induced by anti-arrhythmia agents].
    Medizinische Klinik, 1980, Feb-01, Volume: 75, Issue:3

    Topics: Aged; Agranulocytosis; Ajmaline; Anti-Arrhythmia Agents; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Humans; Middle Aged; Phenylbutazone; Phenytoin; Procainamide; Quinidine; Risk

1980
Biologic interaction of gamma radiation with phenylbutazone, phenytoin, or hydralazine.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 29, Issue:3

    Topics: Animals; Gamma Rays; Glutathione; Hydralazine; Leukocyte Count; Liver; Male; Mice; Phenylbutazone; Phenytoin; Radiation, Ionizing

1980
Differential inhibitory effects of phenytoin, diclofenac, phenylbutazone and a series of sulfonamides on hepatic cytochrome P4502C activity in vitro, and correlation with some molecular descriptors in the dwarf goat (Caprus hircus aegagrus).
    Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:8

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Enzyme Inhibitors; Female; Goats; Hydroxylation; Kinetics; Liver; Microsomes, Liver; Phenylbutazone; Phenytoin; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Sulfaphenazole; Sulfonamides; Tolbutamide

1997
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
    Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:3

    Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics

1999
Drug-plasma protein binding assay by electrokinetic chromatography-frontal analysis.
    Electrophoresis, 2002, Volume: 23, Issue:6

    Topics: beta-Cyclodextrins; Blood Proteins; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Diclofenac; Electrophoresis, Capillary; Humans; Ketoprofen; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Serum Albumin; Sulfathiazole; Sulfathiazoles; Warfarin

2002
STIMULATORY EFFECT OF PHENOBARBITAL ON THE METABOLISM OF DIPHENYLHYDANTOIN.
    The Journal of pharmacology and experimental therapeutics, 1963, Volume: 141

    Topics: Animals; Anti-Allergic Agents; Barbiturates; Dogs; Histamine H1 Antagonists; Metabolism; Mice; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Research

1963
DRUG REACTIONS INVOLVING THE ALIMENTARY TRACT.
    The Medical journal of Australia, 1964, Feb-15, Volume: 1

    Topics: Anticoagulants; Bismuth; Chemical and Drug Induced Liver Injury; Chlorothiazide; Drug Therapy; Esophagus; Gastroenterology; Hepatitis; Intestinal Diseases; Mercury Poisoning; Morphine; Mouth; Pancreas; Phenylbutazone; Phenytoin; Reserpine; Salicylates; Steroids; Stomach; Tooth; Toxicology

1964
APLASTIC VERSUS HYPERPLASTIC BLOOD DYSCRASIAS.
    Postgraduate medicine, 1964, Volume: 35

    Topics: Anemia; Anemia, Aplastic; Anti-Bacterial Agents; Benzene; Bone Marrow Diseases; Chlorpromazine; Cobalt; DDT; Folic Acid Antagonists; Hematology; Humans; Iatrogenic Disease; Leukemia; Nitrogen Mustard Compounds; Nitrous Oxide; Phenylbutazone; Phenytoin; Promazine; Quinacrine; Sulfonamides; Thiouracil; Toxicology; Trinitrotoluene; Vitamins

1964