phenytoin and phenoxybenzamine

phenytoin has been researched along with phenoxybenzamine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199010 (62.50)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's5 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Brouillette, WJ; Brown, GB; Zha, C1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Banna, NR; Kurkjian, R1
Jenkins, LC; Saunders, BA1
Gray, WD; Rauh, CE1
Mennear, JH; Rudzik, AD1
Allen, JC; Davidson, D; Domer, FR1
Bass, DD; Mendeloff, AI; Schuster, MM; Vanasin, B1
Levine, MD; Liston, EH; Philippart, M1
Bhalla, TN; Bhargava, KP; Kohli, RP; Sinha, JN1
Little, JM; Oliver, JH; Pirch, JH1

Reviews

1 review(s) available for phenytoin and phenoxybenzamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

15 other study(ies) available for phenytoin and phenoxybenzamine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
    Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1

    Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels

2014
A novel tremorigen antagonized by D-amphetamine.
    Brain research, 1975, Apr-04, Volume: 87, Issue:1

    Topics: Acetates; Aldehydes; Amines; Animals; Atropine; Calcium; Chlorpromazine; Dextroamphetamine; Diazepam; Diphenhydramine; Ganglionic Stimulants; Histidine; Male; Mice; Oximes; Phenoxybenzamine; Phenytoin; Propranolol; Scopolamine; Thiophenes; Tremor; Trimethadione

1975
Cardiac arrhythmias of central nervous system origin: possible mechanism and suppression.
    Canadian Anaesthetists' Society journal, 1973, Volume: 20, Issue:5

    Topics: 1-Propanol; Adrenergic beta-Antagonists; Amygdala; Animals; Arrhythmias, Cardiac; Atropine; Blood Pressure; Brain; Cats; Caudate Nucleus; Diazepam; Electric Stimulation; Electrocardiography; Electroencephalography; Electrokymography; Globus Pallidus; Heart Rate; Hippocampus; Hypothalamus; Lidocaine; Parasympathomimetics; Phenoxybenzamine; Phenytoin; Reticular Formation; Stereotaxic Techniques; Thalamus

1973
The anticonvulsant action of the carbonic anhydrase inhibitor methazolamide: possible involvement of a noradrenergic mechanism.
    European journal of pharmacology, 1974, Volume: 28, Issue:1

    Topics: Animals; Anticonvulsants; Benserazide; Body Temperature; Carbonic Anhydrase Inhibitors; Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Electroshock; Ethanolamines; Isoproterenol; Levobunolol; Male; Methazolamide; Mice; Motor Activity; Norepinephrine; Phenoxybenzamine; Phentolamine; Phenytoin; Practolol; Propranolol; Rats; Reserpine; Serotonin; Thiazoles; Thiourea; Tolazoline

1974
Antagonism of anticonvulsants by adrenergic blocking agents.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1966, Volume: 122, Issue:1

    Topics: Acetazolamide; Animals; Anticonvulsants; Chlordiazepoxide; Chlorpromazine; Isoproterenol; Mice; Phenoxybenzamine; Phenytoin; Sympatholytics; Tolazoline

1966
Enhancement of diphenylhydantoin-induced anticonvulsant activity of a shaking stress.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 211, Issue:2

    Topics: Animals; Anticonvulsants; Drug Interactions; Electroshock; Epilepsy; Female; Male; Mice; Phenoxybenzamine; Phenytoin; Propranolol; Rats; Stress, Physiological; Time Factors

1974
Alteration of electrical and motor activity of human and dog rectum by diphenylhydantoin.
    The American journal of digestive diseases, 1973, Volume: 18, Issue:5

    Topics: Acetylcholine; Action Potentials; Animals; Colon; Dogs; Electric Stimulation; Hexamethonium Compounds; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Phenoxybenzamine; Phenytoin; Propranolol; Rectum; Serotonin; Time Factors

1973
Psychosis in Fabry disease and treatment with phenoxybenzamine.
    Archives of general psychiatry, 1973, Volume: 29, Issue:3

    Topics: Adult; Bethanechol Compounds; Glycolipids; Humans; Lipid Metabolism, Inborn Errors; Male; Neurocognitive Disorders; Phenoxybenzamine; Phenytoin; Remission, Spontaneous

1973
Aconitine-induced writhing: a method for assessment of analgesic activity.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Aconitum; Analgesics; Animals; Aspirin; Behavior, Animal; Chlorpromazine; Imipramine; Mephenesin; Methaqualone; Methods; Mice; Morphine; Phenoxybenzamine; Phenylbutazone; Phenytoin; Sodium Salicylate

1969
Effect of reserpine and other drugs on the CNS and lethal effects of hyperbaric oxygen in mice.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 183, Issue:2

    Topics: Animals; Central Nervous System; Electroshock; Hyperbaric Oxygenation; Methods; Methyldopa; Methyltyrosines; Mice; Phenoxybenzamine; Phenylalanine; Phenytoin; Reserpine; Seizures; Tranylcypromine

1970