phenytoin has been researched along with phenobarbital in 2392 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1741 (72.78) | 18.7374 |
| 1990's | 294 (12.29) | 18.2507 |
| 2000's | 190 (7.94) | 29.6817 |
| 2010's | 125 (5.23) | 24.3611 |
| 2020's | 42 (1.76) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, H; Edafiogho, IO; Hinko, CN; Moore, JA; Mulzac, D; Nicholson, JM; Scott, KR | 1 |
| Johnson, DN; Kilpatrick, BF; Kinnier, WB; Lo, YS; Moses, LM; Sutherland, DB; Taylor, CR; Tomczuk, BE | 1 |
| Kohn, H; Leander, JD; LeGall, P; Robertson, DW; Sawhney, KN | 1 |
| Edafiogho, IO; Farrar, VA; Moore, JA; Nicholson, JM; Scott, KR | 1 |
| Iqbal, MT; Kwon, CH; Wurpel, JN | 1 |
| Baron, BM; Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM; Staeger, MA | 1 |
| Conley, JD; Kohn, H; Leander, JD; LeGall, P; Robertson, DW; Sawhney, KN | 1 |
| Goehring, RR; Greenwood, TD; Nwokogu, GC; Pisipati, JS; Rogers, TG; Wolfe, JF | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Baker, JK; Wall, GM | 1 |
| Creveling, CR; Daly, JW; Hollingsworth, EB; Lewandowski, G; Waters, JA | 1 |
| Kadaba, PK | 1 |
| Chapleo, CB; Myers, PL; Smith, AC; Tulloch, IF; Turner, S; Walter, DS | 1 |
| Clark, CR; Lin, CM; Sansom, RT | 1 |
| Chapleo, CB; Myers, M; Myers, PL; Saville, JF; Smith, AC; Stillings, MR; Tulloch, IF; Walter, DS; Welbourn, AP | 1 |
| Stillings, MR; Walter, DS; Welbourn, AP | 1 |
| Conley, JD; Kohn, H | 1 |
| Biziere, K; Brochard, J; Brodin, R; Chambon, JP; Hallot, A; Merlier, J | 1 |
| Clark, CR; Lin, CM; Norris, GN; Sansom, RT | 1 |
| Beard, CC; Dvorak, C; Marx, M; Patterson, J; Roszkowski, A; Schuler, M; Unger, SH; Wagner, PJ; Wallach, MB; Weinhardt, K | 1 |
| Clark, CR; Dockens, RC; Norris, GN; Ravis, WR; Sansom, RT; Wells, MJ | 1 |
| Hirschfeld, DR; Walker, KA; Wallach, MB | 1 |
| Alexander, MS; Edafiogho, IO; Farrar, VA; Kolen, KR; Moore, JA; Rankin, GO; Scott, KR; Sims, LD; Stables, JP; Tonnu, AD | 1 |
| Bardel, P; Bolanos, A; Kohn, H | 1 |
| Bastide, P; Coudert, P; Couquelet, J; Gardette, D; Moreau, S; Rubat, C; Tronche, P; Vallee-Goyet, D | 1 |
| Bardel, P; Kohn, H; Leander, JD; Robertson, DW; Sawhney, KN | 1 |
| Ciechanowicz-Rutkowska, M; Edafiogho, IO; el-Assadi, A; Farrar, VA; Filippini, G; Grochowski, J; Hinko, CN; Moore, JA; Pilati, T; Serda, P | 1 |
| Choi, D; Kohn, H; Stables, JP | 1 |
| Flaherty, PT; Greenwood, TD; Manheim, AL; Wolfe, JF | 1 |
| Cacciaguerra, S; Delarge, J; Depovere, P; Isa, M; Masereel, B; Poupaert, JH; Spampinato, S; Stables, JP; Ucar, H; Van derpoorten, K | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Andurkar, SV; Béguin, C; Kohn, H; Stables, JP | 1 |
| Kohn, H; LeTiran, A; Stables, JP | 2 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD | 1 |
| Caron, G; Ermondi, G | 1 |
| Chai, KY; Kwak, KC; Piao, HR; Quan, ZS; Xie, ZF | 1 |
| Pavana, RK; Raghavendran, JV; Sriram, D; Stables, J; Sudhan, K; Thirumurugan, R; Yogeeswari, P | 1 |
| Caruso, F; Doshi, U; Patel, HJ; Rossi, M; Sarra, J; Stephani, RA | 1 |
| Ragavendran, JV; Ranganadh, V; Sahitya, P; Sriram, D; Yogeeswari, P | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Alkskas, IA; Azam, F; Khokra, SL; Prakash, O | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Al-Eryani, YA; Amin, KM; Rahman, DE | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Kohn, H; Morieux, P; Stables, JP | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Jain, NK; Kashaw, SK; Kashaw, V; Mishra, P; Stables, JP | 1 |
| Cotten, SW; Eyers, C; Gaskell, SJ; Kohn, H; Liu, R; Morieux, P; Park, KD; Reamtong, O; Salomé, C; Stables, JP | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| DeMarco, E; Kohn, H; Morieux, P; Park, KD; Salomé, C; Salomé-Grosjean, E; Stables, JP; Swendiman, R | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Ahsan, W; Siddiqui, N | 1 |
| Ahsan, W; Alam, O; Gilani, SJ; Khan, SA; Mullick, P; Siddiqui, N; Verma, SP | 1 |
| Kohn, H; Salomé, C; Salomé-Grosjean, E; Stables, JP | 1 |
| Kohn, H; Morieux, P; Park, KD; Salomé, C; Stables, JP | 1 |
| He, X; Hu, X; Pan, Y; Qiu, G; Wu, W; Wu, Z; Xiao, Y; Yang, J; Zhang, T; Zhong, M | 1 |
| Sen, S; Sinha, N | 1 |
| Deng, XQ; Quan, LN; Quan, ZS; Song, MX; Wei, CX | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| De Ryck, M; Dinsmore, J; Kaminski, R; King, AM; Kohn, H; Salomé, C; Salomé-Grosjean, E; Valade, A | 1 |
| De Ryck, M; Kaminski, R; King, AM; Kohn, H; Salomé, C; Salomé-Grosjean, E; Stables, JP; Valade, A | 1 |
| De Ryck, M; Kaminski, R; King, AM; Kohn, H; Stables, JP; Valade, A | 1 |
| Chodkowski, A; Dawidowski, M; Herold, F; Kleps, J; Szulczyk, P; Wilczek, M | 1 |
| Abdel-Rehim, M; Aboul-Enein, MN; Amin, KM; Attia, MI; El-Azzouny, AA; El-Behairy, MF; Maklad, YA | 1 |
| Guo, H; He, X; Hu, X; Qiu, G; Wu, Z; Xiao, Y; Yang, J; Zhang, T; Zhong, M | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Baruah, PK; De Ryck, M; Dinsmore, J; Kaminski, R; King, AM; Kohn, H; Provins, L; Salomé, C | 1 |
| He, X; Hu, X; Wu, W; Wu, Z; Xiao, Y; Zhang, T; Zhong, M | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Dustrude, ET; Khanna, R; Kohn, H; Lee, H; Park, KD; Wilson, SM; Yang, XF | 1 |
| Chońska, J; Dawidowski, M; Mika, W; Turło, J | 1 |
| Kumari, S; Mishra, CB; Tiwari, M | 1 |
| Cummins, TR; Dustrude, ET; Khanna, R; Kohn, H; Torregrosa, R; Yang, XF | 1 |
| Edayadulla, N; Ramesh, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Akhtar, MJ; Bhatia, R; Grover, G; Nath, R | 1 |
| Chłoń-Rzepa, G; Dąbrowska, M; Jankowska, A; Komsta, Ł; Pawłowski, M; Ślusarczyk, M; Starek, M; Zagórska, A | 1 |
| Eadie, MJ; Lander, CM; Tyrer, JH | 2 |
| Roger, J; Tassinari, CA | 1 |
| Acheampong-Mensah, D | 1 |
| Brandt, S | 1 |
| Bolt, DJ; Cooper, BS; Hawk, HW | 1 |
| Einhorn, R; Franki, N; Hays, RM; Levine, SD | 1 |
| Canonne, MA; Hue, G; Landriau, N; Maitrot, B; Rocher, A | 1 |
| Harner, RS; McDowell, AE; Pardue, HL | 1 |
| Fayle, SA; Leppik, IE; McAuliffe, JJ; Pippenger, CE; Sherwin, AL | 1 |
| Richens, A | 3 |
| Kabra, PM; Marton, LJ; Stafford, BE | 1 |
| Ferrara, SD; Marigo, M; Tedeschi, L | 1 |
| Ahmad, AK; Amer, MM; Hassan, SM | 1 |
| Callaghan, N; Duggan, PF; Feely, M; O'Callaghan, M | 1 |
| Markovich, VV; Ostrovskaia, RU | 1 |
| Kozhechkin, SN; Markovich, VV; Molodavkin, GM; Ostrovskaya, RU; Voronina, TA; Zakusov, VV | 1 |
| Driessen, OM; Goedhart, DM; Meijer, JW | 1 |
| Asai, S; Kubodera, T; Nadai, T; Tatematsu, A; Yoshizumi, H | 1 |
| Cooper, BS; Hawk, HW | 1 |
| Buchthal, A | 1 |
| Bending, MR; Dollery, CT; Kahn, GC; Mucklow, JC | 1 |
| Flachs, H; Gram, L; Parnas, J; Würtz-Jørgensen, A | 1 |
| Brechbühler, T; Schweizer, K; Wick, H | 1 |
| Egli, M | 1 |
| Dreifuss, FE | 2 |
| Feigl, P; Friel, P; Levy, RH; Morretti-Ojemann, L; Troupin, AS; Wilensky, AJ | 1 |
| Elvidge, JA; Jones, JR; Saljoughian, M | 1 |
| Mohrbacher, RJ; Riendeau, CJ; Werner, M | 1 |
| Flachs, H; Gram, L; Parnas, J | 1 |
| Chadwick, D; Jenner, P; Reynolds, EH | 2 |
| Cameron, JD; Hedley, DW | 1 |
| Ludwig, BI; Marsan, CA | 1 |
| Kutt, H | 5 |
| Schmidt, D | 9 |
| Selye, H; Taché, J; Taché, Y | 1 |
| Hansson, O; Sillanpaa, M | 1 |
| Hartz, SC; Heinonen, OP; Mitchell, AA; Monson, RR; Rosenberg, L; Shapiro, S; Siskind, V; Slone, D | 1 |
| Chadwick, D; Galbraith, AW; Reynolds, EH | 1 |
| Elshove, J; Huisjes, HJ; Visner, GH | 1 |
| Lothman, EW; Somjen, GG | 1 |
| Hopkins, A; Scambler, G | 1 |
| Buchanan, N; van der Walt, LA | 1 |
| Johnson, RH; Lambie, DG; Nanda, RN; Shakir, RA | 2 |
| Abarbanel, J; Eylath, U; Herishanu, Y; Rosenberg, P | 1 |
| Cavalier, R; Cumps, J; Toussaint, A | 1 |
| Livingston, S; Pauli, LL; Pruce, I | 4 |
| Howland, C; McLean, AE; White, SJ | 1 |
| Snead, OC | 1 |
| Penin, H | 1 |
| Deisenhammer, E; Sommer, R | 2 |
| Ganes, T; Johannessen, SI; Rootwelt, K | 1 |
| Allen, JP; Hawkins, DW; Hoffman, SF; Ludden, TM | 1 |
| Bruni, J; Wilder, BJ | 1 |
| Rambeck, B | 1 |
| Hanson, HM; Ivester, CA; Morton, BR | 1 |
| Bücking, PH; Regli, F | 1 |
| Karasawa, T; Masuda, Y; Shimizu, M; Shiraishi, Y; Utsui, Y; Yoshida, K | 3 |
| Buda, FB; Joyce, RP | 1 |
| Johnell, O; Nilsson, BE; Wallöe, A; Wiklund, PE | 1 |
| Lidgren, L; Nilsson, BE; Wallöe, A | 1 |
| Broughton, PM; Forsythe, WI; Prendergast, MP; Toothill, C | 1 |
| Bini, PL; Carotti, G; Gaetti, MT; Pellegrini, L; Scalseggi, V; Vianelli, P | 1 |
| Boenigk, HE; May, T; Rambeck, B | 1 |
| Aucamp, AK | 1 |
| Anderson, G; Rassam, JW | 1 |
| Gandhi, IC; Jindal, MN; Patel, VK | 1 |
| Browne, TR | 4 |
| Livingston, HL; Livingston, S; Pauli, LL; Pruce, I | 1 |
| Kubo, H; Nishikawa, T; Saito, M | 1 |
| French, JH; McGregor, PA; Pippenger, CE; Rowan, AJ | 1 |
| Bajc, O; Meienberg, O | 1 |
| Costa, E; Guidotti, A; Mao, CC; Suria, A | 1 |
| Gray, P; Peterson, P; Tolman, KG | 1 |
| Nuttall, FQ; Shafer, RB | 1 |
| Alcalay, M; Amor, B; Bontoux, D; Cayla, J; Charbonnier, A; Mery, C; Miravet, L; Rondier, J | 1 |
| Myllylä, VV | 1 |
| Green, JR; Sato, M; Troupin, AS; Wada, JA; Wake, A | 1 |
| Brereton, HD; Greco, FA; Kolins, J; Rajjoub, RK | 1 |
| Harrison, HC; Harrison, HE | 1 |
| Nistico, G | 1 |
| Bleck, V; Lewin, E | 1 |
| Lison, MP; Speciali, GG | 1 |
| Roginsky, MS; Sulimovici, S | 1 |
| Ferrendelli, JA; Kinscherf, DA | 1 |
| Côté, MG; Gascon-Barré, M | 2 |
| Sotaniemi, S | 1 |
| Hahn, TJ; Halstead, LR; Kahn, AJ; Richardson, CA; Scharp, CR; Teitelbaum, SL | 1 |
| Brodeur, J; Côte, MG; Gascon-Barré, M | 1 |
| Palmer, GC | 1 |
| Jones, DJ; Medina, MA; Palmer, GC; Stavinoha, WB | 1 |
| Boldyrev, AI; Fleĭs, EP; Vaĭntrub, MIa | 1 |
| Nambara, K | 1 |
| Albani, M; Gauchel, FD; Toseland, PA | 1 |
| Plaa, GL | 1 |
| Cohn, WM; Matthay, RA; Neff, TA; Sutton, FD; Weinberger, MM; Zwillich, CW | 1 |
| Horton, RW; Meldrum, BS; Toseland, PA | 1 |
| Layzer, RB; Porter, RJ | 2 |
| Ahmad, S; Houghton, GW; Laidlaw, J; Richens, A | 1 |
| Müller-Oerlinghausen, B | 1 |
| Stores, G | 1 |
| Foss, MC; Meneghelli, UG; Tabosa Veríssimo, JM | 1 |
| Himaya, A; Krzaniak, S; Nuyens, AJ; Pathak, SM; Taylor, GO | 1 |
| Browning, RA; Hoffmann, WE; Simonton, RL | 1 |
| Frank, GB; Neuman, RS | 1 |
| Foss, MC; Veríssimo, JM | 1 |
| McClean, SW; Rodbard, D | 1 |
| McClean, SW; Yonekawa, W; Young, DS | 1 |
| Brown, L; Horning, MG; Kellaway, P; Lertratanangkoon, K; Nowlin, J; Zion, TE | 1 |
| Shirey, TL | 1 |
| Adams, RF | 1 |
| Nelson, JA | 1 |
| Ohno, T; Van Lente, F; Warkentin, D | 1 |
| Sauer, W; Windorfer, A | 1 |
| Brachet-Liermain, A; Jogeix, M; Legroux, M; Loiseau, P | 1 |
| Hammond, KB | 1 |
| Brett, E | 1 |
| Stünkel, S; Weinmann, HM; Windorfer, A | 1 |
| Trompetter-van Woerden, ML; van der Zwan, A | 1 |
| Gascon Barré, M | 1 |
| London, M; Sanabria, D; Yau, D | 1 |
| Ahuja, KK; Karmen, A; Lasky, FD | 1 |
| Turri, JJ | 1 |
| Flachs, H; Gram, L; Lohren, V; Rasmussen, KE; Sommerbeck, KW; Wulff, K; Würtz-Jorgensen, A | 1 |
| Johannessen, SI | 1 |
| Araki, Y; Ueki, S; Watanabe, S | 1 |
| Haeckel, R; Heyer, R; Külpmann, WR; Oellerich, M | 1 |
| Aucamp, AK; Joubert, PH; Potgieter, GM; Verster, F | 1 |
| Jeavons, PM | 1 |
| Klotz, U | 2 |
| Long, JP | 1 |
| Hori, M; Ito, T; Shimizu, M; Yoshida, K | 3 |
| Vassella, F | 1 |
| Fröscher, W; Gugler, R; Schulz, HU | 1 |
| Bielmann, P; Gagnon, MA; Levac, T | 1 |
| Krall, RL; Kupferberg, HJ; Penry, JK; Swinyard, EA | 1 |
| Conomy, JP | 1 |
| Aymard, P; Boulu, RG; Sarhan, N | 1 |
| Helmsing, PJ; van der Woude, J; van Eupen, OM | 1 |
| Miyamura, S; Yamada, M | 1 |
| Göbel, W; Löscher, W | 1 |
| Fishman, MA | 1 |
| Christensen, NJ | 1 |
| Levy, RH; Patel, IH | 1 |
| Bruni, J | 3 |
| Campbell, DJ; Godolphin, W; Urquhart, N | 1 |
| Kramer, II; Livingston, S; Pauli, LL; Pruce, I | 2 |
| Newmark, ME; Penry, JK | 1 |
| Andersen, B; Flachs, H; Gram, L; Parnas, J; Würtz-Jørgensen, A | 1 |
| Reith, H; Schäfer, H | 1 |
| Curless, RG | 1 |
| Trimble, M | 1 |
| Crawford, RD; Davis, HL; Johnson, DD | 1 |
| Deleide, G; Donà, V; Malvano, R | 1 |
| Berchou, RC; Lodi, RA; Sherman, JA | 1 |
| Fretthold, DW; Kumar, S; Pesh-Imam, M; Sunshine, I; Terrentine, S; Willis, CE | 1 |
| Munshi, AT; Sarkar, TK | 1 |
| Harvey, CD; Sherwin, AL; Van Der Kleijn, E | 1 |
| Wada, JA | 1 |
| Diehl, LW | 1 |
| Mercier-Parot, L; Tuchmann-Duplessis, H | 1 |
| Hosokawa, K; Kugoh, T | 2 |
| Hayashi, K; Shimizu, H; Takemura, N | 1 |
| Livingston, S | 4 |
| Swanson, PD | 1 |
| Friis, ML | 1 |
| Stünkel, S; Windorfer, A | 1 |
| Trebbin, WM | 1 |
| Borel, JD; Dooley, JR; Mazze, RI; Rice, SA | 1 |
| Freeman, DJ; Rawal, N | 1 |
| Dymling, JF; Lidgren, L; Wallöe, A | 1 |
| Burk, PG; Nathanson, G; Pollack, MA | 1 |
| Leppik, IE; Sherwin, AL | 2 |
| Bäckström, T; Jorpes, P | 1 |
| Anglim, MA; Dolar, E; Least, CJ; St Onge, LM | 1 |
| Fröscher, W | 1 |
| Caughey, GH; Kosek, JC; Mazze, RI; Rice, SA | 1 |
| Balthazar, A; Rosman, PM; Sacerdote, A; Wallace, EZ | 1 |
| Ashton, D; Melis, W; Wauquier, A | 1 |
| Rylance, GW | 1 |
| Hammond, EJ; Perchalski, RJ; Ramsay, RE; Wilder, BJ | 1 |
| Gilbert, JC; Jeffers, TA; Petrie, JC; Scott, AK | 1 |
| Kelly, D; Reed, B; Scott, J; Weir, D | 1 |
| Eisenberg, Z; Fattal, A; Harel, S; Harell, A; Spirer, Z; Weisman, Y | 1 |
| Tamura, Z | 1 |
| Workman, P | 1 |
| Beaver, RW; Brauer, RW; Fuquay, J | 1 |
| Honda, Y; Kohda, Y; Nishihara, K; Saitoh, Y | 1 |
| Hattori, M; Kazamatsuri, H | 1 |
| Shimizu, H | 1 |
| Galli, A; Zaccara, G | 1 |
| Kurata, K | 1 |
| Leuschner, U; Quednow, B; Walther, H | 1 |
| Schain, RJ | 1 |
| Eadie, MJ; Edwards, VE; Lander, CM; Tyrer, JH | 1 |
| Boisse, NR; Okamoto, M; Rosenberg, HC | 1 |
| Goldberg, MA | 1 |
| Novack, GD; Stark, LG | 1 |
| Ramsay, RE; Strauss, RG; Wilder, BJ; Willmore, LJ | 1 |
| Barragry, JM; Makin, HL; Scott, DF; Trafford, DJ | 1 |
| Wolf, SM | 1 |
| Wilensky, AJ | 1 |
| Abraham, CV; Gresham, D | 1 |
| Boenigk, HE; Rambeck, B; Stenzel, E | 1 |
| Hoffer, BJ; Oliver, AP; Wyatt, RJ | 1 |
| Varma, R | 2 |
| Kent, GN; Levison, JC; Retallack, RW; Worth, GK | 1 |
| Brevik, JI; Hansen, T; Lindén, V | 1 |
| de Crousaz, G; Schelling, JL | 1 |
| Fanard, A; Goedhard, A; Picazo, J | 1 |
| Buchanan, N | 2 |
| Eickhoff, K; Heipertz, R; Pilz, H; Seidel, D | 1 |
| Kaneko, S | 2 |
| Singh, RK; Teotia, M; Teotia, SP | 1 |
| Betancourt Rovira, A; Flores García, R; Gutiérrez Calzado, C; Rodríguez Rivera, L; Sánchez Castillo, A | 1 |
| Kutt, H; Louis, S; Newman, SM; Turner, IM | 1 |
| Castro, A; Jatlow, PI; Malkus, H | 1 |
| MacDonald, H; Painter, MJ; Pippenger, C; Pitlick, W | 1 |
| Penry, JK; Wolpaw, JR | 1 |
| de Zeeuw, RA; Oei, TT; van der Kleijn, E; Westenberg, HG | 1 |
| Castagna, F; Ferrara, SD; Marigo, M; Tedeschi, L | 1 |
| Plenge, KL | 1 |
| Matarazzo, EB | 1 |
| Benetello, P; Da Ronch, A; Furlanut, M; Testa, G | 1 |
| Savulich, A; Spiegel, HE; Symington, J | 1 |
| Demers, LM; Krieg, AF; Miller, DT | 1 |
| Köhler, E; Leuschner, U; Meyer, FP; Quednow, B; Walther, H | 1 |
| Hadden, DR; Maclay, E; McIlrath, EM; Nesbitt, GS | 1 |
| Bates, D; Evered, DC; Heath, A; Howe, JG; Ratcliffe, WA; Schardt, CW; Yeo, PP | 1 |
| Benetello, P; Furlanut, M; Testa, G | 1 |
| Alberts, M; Terrence, C | 1 |
| Bentjerodt, O; Concha, G; Galdames, D; Morales, E; Saavedra, I; Valenzuela, AL | 1 |
| Dollery, CT; Mucklow, JC | 1 |
| Rosenmund, H; Wad, N | 1 |
| Browning, RA; Simonton, RL | 1 |
| Davis, CM; Fenimore, DC; Meyer, CJ | 1 |
| Burke, DG; Halpern, B; Korth, J; Summons, R; Truscott, RJ | 1 |
| Buchanan, N; Freiman, J | 1 |
| Shihabi, ZK | 1 |
| Crunelli, V; Quattrone, A; Samanin, R | 1 |
| Mimaki, T; Seino, Y; Shimotsuji, T; Sugita, T; Sumi, K; Yabuuchi, H | 1 |
| Hewitt, TE; Kessler, G; Sievers, DL | 1 |
| Bruck, E; Colburn, WA; Gibaldi, M; Hilligoss, DM; Koup, JR; McNamara, P | 1 |
| Passarge, C | 1 |
| Guelen, P; Knop, H; Schobten, F; van der Kleijn, E; Vree, T; Westenberg, H | 1 |
| Flanagan, RJ; Rutherford, DM | 1 |
| Goldman, P; Ingelfinger, JA; Isakson, G; McCormick, W | 1 |
| Darley, CR; Kirby, JD | 1 |
| Culpin, PA | 1 |
| Bustamante, SA; Stumpff, LC | 1 |
| Rosnowska, M; Szukalski, B; Zieliński, JJ | 1 |
| Ravindran, M | 1 |
| Brockman, WH; Strain, GM; Van Meter, WG | 1 |
| Christiansen, J; Friis, ML; Hvidberg, EF | 1 |
| Brown, HW; Clark, BG; Dawson, GW | 1 |
| Buck, DR; Hendricks, DG; Mahoney, AW | 1 |
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| Chawla, D; Goel, SP; Pathak, G; Pathak, U; Upadhyay, A | 1 |
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| Benjaponpitak, S; Kamchaisatian, W; Manuyakorn, W; Pakakasama, S; Rujirawat, T; Siripool, K; Vilaiyuk, S; Visudtibhan, A | 1 |
| Boyer, EW; Burns, JM; Manno, M; Marino, A; Rhyee, S | 1 |
| Dutta, S | 1 |
| Jabłoński, M; Majdan, M; Nowicka-Stążka, P; Parada-Turska, J; Rzeski, W; Turski, WA | 1 |
| Panomvana, D; Towanabut, S; Traiyawong, T | 1 |
| Chowdhury, AH; Chowdhury, RN; Ghose, SK; Habib, M; Haque, B; Hasan, AT; Hoque, A; Khan, SU; Mohammad, QD; Mondal, BA; Rahman, KM | 1 |
| Sahu, JK | 1 |
| Upadhyay, A | 1 |
| Lang, LM; Linnet, K | 1 |
| Chen, XY; He, L; Li, Q; Zhou, D | 1 |
| Ansary, A; Ibhanesebhor, S; Manjunatha, C | 1 |
| Barclay, ML; Begg, EJ; Chin, PK; Jensen, BP; Patterson, DM; Roberts, RL; Wallace, MC; Wright, DF; Zhang, M | 1 |
| Chiarelli, F; Cofini, M; Scaparrotta, A; Tiboni, GM; Verrotti, A | 1 |
| Borowicz, KK; Borowicz, KM; Latalski, M; Zarczuk, R | 1 |
| Czuczwar, SJ; Świąder, MJ | 1 |
| Yamanouchi, H | 1 |
| de Saint-Martin, A; Laugel, V | 1 |
| Lubszky, S; Reinhart, WH; Schulzki, T; Thöny, S | 1 |
| Al-Roomi, K; Krishnan, PR; Prasad, M; Sequeira, R | 1 |
| Alves, G; Falcão, A; Ferreira, A; Fortuna, A; Francisco, J; Oliveira, P; Rodrigues, M; Rosado, L; Rosado, P | 1 |
| Boussadia, B; de Bock, F; Ghosh, C; Janigro, D; Marchi, N; Pascussi, JM; Plaud, C; Rousset, MC | 1 |
| Bankstahl, M; Klein, S; Löscher, W | 1 |
| Andres-Mach, M; Baumann, MH; Luszczki, JJ; Prisinzano, TE; Zolkowska, D | 1 |
| Greenhalgh, J; Marson, AG; Weston, J | 1 |
| Egusa, M; Higuchi, H; Ishii-Maruhama, M; Maeda, S; Miyawaki, T; Tomoyasu, Y | 1 |
| Abbasi, B; Asadi, M; Dadfarnia, S; Haji Shabani, AM | 1 |
| Ames, MM; Berg, AK; Buckner, JC; Galanis, E; Jaeckle, KA; Reid, JM | 1 |
| Florek-Luszczki, M; Glensk, M; Glowniak, K; Luszczki, JJ; Pyrka, D; Skalicka-Wozniak, K; Zagaja, M | 1 |
| Bamford, A; Clarke, A; Crowe, BH; Hacohen, Y; Lim, M; Lin, JP; Pullaperuma, SP; Sancho-Shimizu, V; Tudor-Williams, G; Vincent, A | 1 |
| Cock, HR | 1 |
| Liu, DQ; Ma, HY; Sheng, YH; Wang, C; Wang, P; Yin, T; Zhou, BT | 1 |
| Dwivedi, R; Gupta, YK; Kaleekal, T; Singh, M; Tripathi, M | 1 |
| Shi, J; Wang, LK; Wu, GF; Zhou, F | 1 |
| Dixit, V; Hariparsad, N; Moore, A; Tsao, H | 1 |
| Banach, M; Borowicz-Reutt, KK; Piskorska, B | 2 |
| Bae, EK; Jang, IJ; Kim, TJ; Lee, J; Lee, KJ; Lee, SK; Moon, J; Shin, D; Shin, JW; Shin, YW | 1 |
| Barczyński, B; Czuczwar, SJ; Świąder, K; Świąder, MJ; Tomaszewski, M | 1 |
| Almond, LM; Gardner, I; Hatley, O; Jamei, M; Kenny, JR; Mukadam, S; Okialda, K; Rostami-Hodjegan, A; Rowland-Yeo, K; Tay, S; Wong, S | 1 |
| Abe, S; Azuma, Y; Ishihara, N; Ito, Y; Itomi, K; Kidokoro, H; Kojima, S; Kurahashi, H; Kurahashi, N; Maruyama, K; Natsume, J; Negoro, T; Okumura, A; Suzuki, M; Takeuchi, T; Tsuji, T; Watanabe, K; Yamada, K; Yamamoto, H | 1 |
| Bártfai, G; Devosa, I; Szok, D; Vanya, M | 1 |
| Berg, M; Soll, R; Young, L | 1 |
| Fan, Y; Ma, K; Qu, L; Wang, W; Yin, Z | 1 |
| Asadi, F; Moradian, M; Moradian, N; Sedighi, M; Vakiliamini, M | 1 |
| Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS | 1 |
| Ahmad, KA; Ahmad, SF; Bennett, MM; Clark, RH; Desai, SJ; Ng, YT; Tolia, VN | 1 |
| Bruno Blanch, L; Castaño, R; Enrique, A; Girardi, E; Goicoechea, S; Orozco, S; Rocha, L; Taborda, F | 1 |
| Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J | 2 |
| Methaneethorn, J; Panomvana, D; Vachirayonstien, T | 1 |
| Brown, H; Dionisio, S; Gillinder, L; Lehn, A | 1 |
| Battaglia, A; Carey, JC; Ho, KS; Lortz, A; Markham, LM; Newcomb, T; Olson, LM; Sheng, X; Twede, H; Wassman, ER; Weng, C | 1 |
| Haslemo, T; Hole, K; Molden, E; Nguyen, C; Wollmann, BM | 1 |
| Battino, D; Bonizzoni, E; Craig, J; Lindhout, D; Perucca, E; Sabers, A; Thomas, SV; Tomson, T; Vajda, F | 1 |
| Dundar, Y; Greenhalgh, J; Marson, AG; Nevitt, SJ; Weston, J | 2 |
| Florek-Luszczki, M; Luszczki, JJ; Mazurkiewicz, LP; Ossowska, G; Szpringer, M; Wlaz, A; Wroblewska-Luczka, P; Zolkowska, D | 1 |
| de Baat, C; Vissink, A; Zweers, PGMA | 1 |
| Horino, A; Imai, K; Inoue, Y; Kagawa, Y; Nishida, T; Takahashi, Y; Usui, N; Yamamoto, Y | 1 |
| Francesconi, P; Gualdani, E; Palumbo, P; Policardo, L; Zaccara, G | 1 |
| Barbas, LAL; de Mello, VJ; do Nascimento, JLM; Dos Santos Batista, L; Dos Santos Batista, P; Farias, RAF; Gomes-Leal, W; Hamoy, M; Hutchison, WD; Marcondes, HC; Taylor, JG; Torres, MF | 1 |
| Hatanaka, M; Ikeda, R; Matsumoto, N; Oda, Y; Sonoda, J; Tazaki, T; Yoshikawa, N | 1 |
| Chmielewski, J; Daniluk, J; Florek-Łuszczki, M; Karwan, S; Sawicka, KM; Wawryniuk, A; Łuszczki, JJ | 1 |
| Gut-Lepiech, A; Karwan, S; Kondrat-Wróbel, MW; Marzeda, P; Plech, T; Wróblewska-Łuczka, P; Łuszczki, JJ | 1 |
| Ishikawa, N; Kobayashi, M; Kobayashi, Y; Tani, H; Tateishi, Y | 1 |
| Capovilla, G; Consonni, D; De Liso, P; Di Capua, M; Dilena, R; Falsaperla, R; Pisani, F; Pruna, D; Suppiej, A; Vitaliti, G | 1 |
| Gaínza-Lein, M; Lamb, N; Loddenkemper, T; Sánchez Fernández, I | 1 |
| Jezela-Stanek, A; Koppolu, A; Kosińska, J; Paprocka, J; Płoski, R; Rydzanicz, M; Stawiński, P | 1 |
| Go, S; Kawashima, H; Shimura, M; Takahashi, H; Yamada, H; Yamada, N; Yamanaka, G | 1 |
| Guofeng, W; Kang, Y; Shi, H; Wang, L | 1 |
| Ouchi, K | 1 |
| Berha, AB; Engidawork, E; Gebrewold, MA; Nasir, BB; Woldu, MA; Yifru, YM | 1 |
| Bien, CG; Brandt, C; Hagemann, A; Klimpel, D; May, TW | 1 |
| Charlier, C; Dubois, N; Gilson, M; Sqalli, G | 1 |
| Limotai, C; Limotai, N; Mokklaew, J; Pattanasilp, B; Phayaph, N | 1 |
| Alix, V; Jackson, AH; James, M; Singh, R; Visintainer, PF | 1 |
| Abend, NS; Amengual-Gual, M; Anderson, A; Arya, R; Brenton, JN; Carpenter, JL; Chapman, K; Clark, J; Farias-Moeller, R; Gaillard, WD; Gaínza-Lein, M; Glauser, T; Goldstein, JL; Goodkin, HP; Guerriero, RM; Kapur, K; Lai, YC; Loddenkemper, T; McDonough, TL; Mikati, MA; Morgan, LA; Novotny, EJ; Ostendorf, AP; Payne, ET; Peariso, K; Piantino, J; Riviello, JJ; Sannagowdara, K; Tasker, RC; Tchapyjnikov, D; Topjian, A; Vasquez, A; Wainwright, MS; Wilfong, A; Williams, K | 1 |
| Araki, Y; Fukushima, Y; Imai, K; Kagawa, Y; Takahashi, Y; Terada, K; Yamamoto, Y | 1 |
| Asai, S; Imai, K; Kagawa, Y; Nishida, T; Shiratani, Y; Takahashi, Y; Usui, N; Yamamoto, Y | 1 |
| Drabik, M; Florek-Łuszczki, M; Głuszak, M; Jankiewicz, M; Kozińska, J; Plech, T; Plewa, Z; Wróblewska-Łuczka, P; Łuszczki, JJ | 1 |
| Jimenez, HR; Natali, KM; Slim, J | 1 |
| Banach, M; Borowicz-Reutt, KK | 1 |
| Demir, O; Kaplan, YC | 1 |
| Kumar, J; Meena, J; Saini, L; Yadav, J | 1 |
| Douxfils, J; Hainaut, P; Hardy, M; Larock, AS; Lessire, S; Mullier, F; Sennesael, AL; Spinewine, A | 1 |
| Afshar Mogaddam, MR; Farajzadeh, MA; Jouyban, A; Khosrowshahi, EM; Nemati, M; Tuzen, M | 1 |
| Bertram, EH; Edelbroek, P | 1 |
| Ahmad, KA; Bennett, M; Hamrick, SEG; Patel, RM; Sewell, EK; Tolia, VN | 1 |
| Adams, J; Carlson, JM; Dhillon, R; Holmes, LB; Janulewicz, PA; Macklin, EA; Phillips, C; Schomer, DL; Tosches, WA | 1 |
| Bishop, C; Bonkovsky, HL; Ma, CD; Van Horn, CG; Wan, M | 1 |
| Babl, FE; Borland, ML; Dalziel, SR; Emeto, TI; Furyk, JS; George, S; Hearps, SJ; O'Brien, S; Phillips, N; Riney, K; Watt, K; Wilson, C | 1 |
| Cai, M; Guo, X; Han, Y; Lin, W; Yang, J; Zhong, R | 1 |
| Dolatabadi, R; Mohammadi, A; Walker, RB | 1 |
| Allegaert, K; Yalcin, N | 1 |
| Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T | 1 |
| Aneja, S; Arya, R; Cunningham, J; Jain, P; Sharma, S | 1 |
| García-Peñas, JJ; González-Alguacil, E; Soto-Insuga, V | 1 |
| Banach, M; Borowicz-Reutt, K | 2 |
| Araújo, DB; Azevedo, JEC; Barbas, LAL; da Silva, ALM; Hamoy, AO; Hamoy, M; Lopes, DCF; Lopez, MEC; Mello, VJ; Nascimento, CP; Pereira, RG; Rodrigues, SF; Vieira, LR | 1 |
| Asakawa, R; Honobe-Tabuchi, A; Kagawa, Y; Kawamura, T; Maejima, E; Mitsui, H; Ogawa, Y; Okamoto, T; Shimada, S | 1 |
| Bernat, P; Kołodziejczyk, P; Tutka, P; Zagaja, M; Łuszczki, JJ | 1 |
| Amadori, E; Assenza, G; Cappanera, S; Cerminara, C; D'Onofrio, G; De Giorgis, V; Marini, C; Pietrafusa, N; Rasmini, P; Riva, A; Roberti, R; Russo, E; Specchio, N; Striano, P; Tombini, M; Vari, MS; Veggiotti, P; Zara, F | 1 |
| Bettinotti, M; Boldt, ABW; de Paola, L; Glehn, CQCV; Silvado, CES; Spina Tensini, T | 1 |
| Bojar, H; Chmielewski, J; Florek-Łuszczki, M; Jankiewicz, K; Skalicka-Woźniak, K; Łuszczki, JJ | 1 |
| Anilanmert, B; Caglar-Andac, S; Narin, I | 1 |
| Abiramalatha, T; Brigo, F; Hartmann, H; Pressler, R; Ramaswamy, VV; Thanigainathan, S | 1 |
| Czabanka, M; Kieslich, M; Merker, M; Purwien, L; Ronellenfitsch, MW; Rosenow, F; Schubert-Bast, S; Strzelczyk, A; Willems, LM | 1 |
209 review(s) available for phenytoin and phenobarbital
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Synthetic and therapeutic perspectives of nitrogen containing heterocycles as anti-convulsants.
Topics: Animals; Anticonvulsants; Heterocyclic Compounds; Humans; Molecular Structure; Seizures; Structure-Activity Relationship | 2020 |
Interactions with antiepileptic drugs.
Topics: Acetaminophen; Acetazolamide; Anti-Anxiety Agents; Anticoagulants; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Furosemide; Gonadal Steroid Hormones; Griseofulvin; Humans; Phenobarbital; Phenytoin; Primidone; Thiazines; Urea; Valproic Acid; Vitamin D | 1977 |
[Pharmacotherapy of epilepsy. II].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines; Valproic Acid | 1978 |
Psychotropic effect of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Mental Processes; Personality Inventory; Phenobarbital; Phenytoin; Psychiatric Status Rating Scales; Psychotropic Drugs; Thiazines; Valproic Acid | 1979 |
[Long-term anticonvulsant therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Epilepsy; Ethosuximide; Humans; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
Valproic acid. Review of a new antiepileptic drug.
Topics: Adolescent; Adult; Animals; Brain Chemistry; Drug Interactions; Electric Stimulation; Electroencephalography; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; gamma-Aminobutyric Acid; Half-Life; Humans; Intestinal Absorption; Mice; Phenobarbital; Phenytoin; Seizures; Sleep Stages; Valproic Acid | 1979 |
[Dysmorphisms and psychomotor retardation in infants of mothers treated with anticonvulsants in pregnancy].
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Epilepsy, Tonic-Clonic; Female; Fetus; Humans; Infant, Newborn; Macroglossia; Nose; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Psychomotor Disorders; Skull; Toes | 1979 |
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Primidone; Spasms, Infantile; Status Epilepticus; Thyroid Gland | 1979 |
Drug therapy reviews: drug therapy of status epilepticus.
Topics: Anesthesia, General; Diazepam; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Kinetics; Lidocaine; Neuromuscular Nondepolarizing Agents; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus | 1978 |
New concepts on the mechanism of action of benzodiazepines.
Topics: Animals; Benzodiazepines; Cerebellum; Chlordiazepoxide; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glycine; Humans; Isoniazid; Medulla Oblongata; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Receptors, Drug; Seizures; Sensory Receptor Cells; Spinal Cord; Strychnine; Substantia Nigra | 1975 |
The medical treatment of epilepsy: initiation of drug therapy.
Topics: Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Bromides; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Acute toxicity of antiepileptic drugs.
Topics: Acute Disease; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Dogs; Humans; Phenobarbital; Phenytoin; Poisoning; Primidone; Thiazines | 1975 |
Behavioural effects of anti-epileptic drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Confusion; Disorders of Excessive Somnolence; Epilepsy; Ethosuximide; Humans; Hyperkinesis; Learning Disabilities; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Psychoses, Substance-Induced; Psychotropic Drugs; Thiazines | 1975 |
The determination of anticonvulsants in biological samples by use of high-pressure liquid chromatography.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Mathematics; Phenacetin; Phenobarbital; Phenytoin; Primidone; Spectrophotometry, Ultraviolet; Succinimides; Temperature | 1977 |
Some clinical and pharmacological applications of high-speed liquid chromatography.
Topics: Adenosine; Adenosine Deaminase; Animals; Chemistry, Clinical; Chromatography, High Pressure Liquid; Dogs; Enzymes; Erythrocytes; Humans; Hypoxanthines; Inosine; Mustard Compounds; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Ribonucleotides | 1977 |
Drugs and children: methods for therapeutic monitoring.
Topics: Carbamazepine; Child; Child, Preschool; Chloramphenicol; Chromatography, Gas; Colorimetry; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Gentamicins; Humans; Immunoassay; Infant; Infant, Newborn; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Quality Control; Spectrophotometry; Sulfonamides; Theophylline | 1977 |
[Laboratory controls in long-term treatment with anticonvulsive drugs (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Intestinal Absorption; Male; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid | 1977 |
[Treatment of epileptics with the aid of antiepileptic drug blood level determinations (author's transl)].
Topics: Anticonvulsants; Biological Availability; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Humans; Patient Acceptance of Health Care; Phenobarbital; Phenytoin; Saliva; Therapeutic Equivalency | 1977 |
[Vitamin D: influence of anticonvulsant drugs on its metabolism].
Topics: Animals; Anticonvulsants; Dihydroxycholecalciferols; Humans; Hydroxycholecalciferols; Hydroxylation; Kidney; Liver; Phenobarbital; Phenytoin; Primidone; Vitamin D; Vitamin D Deficiency | 1977 |
[Epilepsies of infancy and early childhood (author's transl)].
Topics: Clonazepam; Electroencephalography; Epilepsy; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Phenobarbital; Phenytoin; Prognosis | 1978 |
[Valproic acid in the treatment of epilepsy with special emphasis on serum level determination (author's transl)].
Topics: Blood Platelets; Drug Interactions; Electroencephalography; Epilepsy; Fatigue; Half-Life; Humans; Phenobarbital; Phenylbutazone; Phenytoin; Protein Binding; Salicylates; Sulfadimethoxine; Valerates; Valproic Acid | 1978 |
[Assay of phenobarbital and phenytoin: critical review (proceedings)].
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Fluorometry; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Radioimmunoassay; Spectrophotometry | 1978 |
Febrile seizures: the treatment controversy.
Topics: Child; Epilepsy; Humans; Nervous System Diseases; Phenobarbital; Phenytoin; Recurrence; Seizures; Seizures, Febrile; Time Factors | 1979 |
Febrile convulsions: diagnosis, treatment, and prognosis.
Topics: Child; Epilepsy; Humans; Infant; Intellectual Disability; Intelligence; Meningitis; Phenobarbital; Phenytoin; Prognosis; Recurrence; Risk; Seizures; Seizures, Febrile; Spinal Puncture | 1979 |
[Antiepileptics during pregnancy and lactation. Pharmacokinetic data].
Topics: Anticonvulsants; Bromides; Carbamazepine; Clonazepam; Diazepam; Ethosuximide; Female; Fetus; Humans; Kinetics; Lactation; Maternal-Fetal Exchange; Nitrazepam; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1979 |
The medical treatment of epilepsy: maintenance of drug therapy.
Topics: Adolescent; Adult; Anticonvulsants; Biological Availability; Bromides; Carbamazepine; Child; Dextroamphetamine; Drug Administration Schedule; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Menstruation; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1979 |
The effect of anti-convulsant drugs on cognitive abilities.
Topics: Anticonvulsants; Carbamazepine; Cognition; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Psychological Tests | 1979 |
Pharmacological and biochemical studies in epileptic fowl.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Brain; Chickens; Disease Models, Animal; Ethosuximide; Female; Humans; Male; Mutation; Phenobarbital; Phenytoin; Photic Stimulation; Primidone; Seizures; Valproic Acid | 1979 |
Pharmacological prophylaxis in the kindling model of epilepsy.
Topics: Amygdala; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Atropine; Aziridines; Carbamazepine; Catecholamines; Cats; Cerebral Cortex; Chlorpromazine; Clorazepate Dipotassium; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy; Haplorhini; Hydroxydopamines; Phenobarbital; Phenytoin; Rats; Reserpine; Seizures; Valproic Acid | 1977 |
Management of seizure disorders: selected aspects. Part I.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Child; Chromatography, Gas; Chromatography, Liquid; Diazepam; Epilepsy; Humans; Infant; Infant, Newborn; Paraldehyde; Phenobarbital; Phenytoin; Protein Binding; Seizures | 1976 |
Clinical pharmacokinetics of anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Interactions; Ethosuximide; Female; Humans; Hydantoins; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Kidney Diseases; Kinetics; Liver Diseases; Milk; Molecular Biology; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1976 |
Drug metabolism in the human neonate.
Topics: Adult; Animals; Barbiturates; Caffeine; Epoxy Compounds; Female; Humans; Infant, Newborn; Labor, Obstetric; Lactation; Maternal-Fetal Exchange; Meperidine; Milk; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Placenta; Pregnancy; Time Factors | 1975 |
Drug metabolism in uremia.
Topics: Acetohexamide; Animals; Antipyrine; Humans; Hydrolysis; Lipid Metabolism; Microsomes, Liver; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Procainamide; Rats; Tolbutamide; Uremia; Vitamin D | 1975 |
Neonatal seizures and their treatment.
Topics: Anticonvulsants; Diazepam; Humans; Hypocalcemia; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Magnesium; Meningitis; Phenobarbital; Phenytoin; Seizures; Sepsis; Vitamin B 6 Deficiency | 1975 |
[Neurotoxicity of antiepileptic drugs].
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Ethosuximide; Humans; Male; Nervous System; Nervous System Diseases; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1992 |
Rational use of antiepileptic drug levels.
Topics: Carbamazepine; Half-Life; Humans; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1992 |
Therapeutic drug monitoring and pharmacokinetic dose prediction methods.
Topics: Aminoglycosides; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy; Flucytosine; Humans; Immunoenzyme Techniques; Pharmacokinetics; Phenobarbital; Phenytoin; Prospective Studies; Theophylline | 1992 |
Therapeutic drug monitoring for the 1990s: meeting the laboratory needs of a changing environment.
Topics: Digoxin; Dose-Response Relationship, Drug; Drug Monitoring; Forecasting; Humans; Immunoenzyme Techniques; Pharmacokinetics; Phenobarbital; Phenytoin; Theophylline | 1992 |
CEDIA--homogeneous immunoassays for the 1990s and beyond.
Topics: Digitoxin; Digoxin; Dose-Response Relationship, Drug; Drug Monitoring; Humans; Hydrocortisone; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Theophylline | 1992 |
Status epilepticus. Clinical features, pathophysiology, and treatment.
Topics: Benzodiazepines; Clinical Protocols; Drug Therapy, Combination; Humans; Phenobarbital; Phenytoin; Status Epilepticus | 1991 |
Anticonvulsants: pharmacotherapeutic issues in the critically ill patient.
Topics: Anticonvulsants; Benzodiazepines; Brain Injuries; Carbamazepine; Central Nervous System Diseases; Epilepsy; Humans; Pentobarbital; Phenobarbital; Phenytoin; Postoperative Complications; Seizures; Substance Withdrawal Syndrome | 1991 |
Cognitive effects of antiepileptic drugs.
Topics: Anticonvulsants; Brain Diseases; Carbamazepine; Cognition; Drug Tolerance; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
The pharmacokinetics of agents used to treat status epilepticus.
Topics: Anticonvulsants; Diazepam; Dose-Response Relationship, Drug; Humans; Injections, Intramuscular; Lipid Metabolism; Phenobarbital; Phenytoin; Solubility; Status Epilepticus | 1990 |
Antiepileptic drugs, cognitive function, and behavior in children: evidence from recent studies.
Topics: Adult; Age Factors; Anticonvulsants; Carbamazepine; Child; Cognition; Cognition Disorders; Epilepsy; Humans; Phenobarbital; Phenytoin; Psychological Tests; Research Design; Valproic Acid | 1990 |
Poisoning by anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1989 |
[Problems of neurological drug therapy in pregnancy].
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Antiparkinson Agents; Carbamazepine; Chelating Agents; Female; Fetus; Haloperidol; Humans; Nervous System Diseases; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Trimethadione; Valproic Acid | 1989 |
Efficacy and adverse effects of antiepileptic drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy | 1989 |
Treatment of status epilepticus.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Child; Humans; Phenobarbital; Phenytoin; Status Epilepticus | 1989 |
[GABAergic theory of epilepsy].
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Benzodiazepines; Bicuculline; Brain; Dogs; Epilepsy; gamma-Aminobutyric Acid; Humans; Mice; Nerve Endings; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Receptors, GABA-A; Synapses; Valproic Acid | 1986 |
Therapeutic drug monitoring in childhood.
Topics: Aminoglycosides; Anti-Bacterial Agents; Carbamazepine; Child; Chloramphenicol; Digoxin; Drug Interactions; Half-Life; Humans; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Saliva; Theophylline; Valproic Acid | 1986 |
Carbamazepine drug interactions.
Topics: Carbamazepine; Cimetidine; Dextropropoxyphene; Drug Interactions; Erythromycin; Humans; Isoniazid; Lithium; Phenobarbital; Phenytoin; Primidone; Protein Binding; Troleandomycin; Valproic Acid; Warfarin | 1986 |
Antiepileptic drugs in adolescents.
Topics: Adaptation, Psychological; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Sports; Valproic Acid | 1987 |
Mechanisms of anticonvulsant drug action. I. Drugs primarily used for generalized tonic-clonic and partial epilepsies.
Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Humans; Kinetics; Phenobarbital; Phenytoin | 1987 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1987 |
[Modification of peripheral thyroid hormone metabolism by drugs].
Topics: Amiodarone; Antipyrine; Dexamethasone; Heparin; Humans; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Rifampin; Thiouracil; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1988 |
Anticonvulsant drugs and cognitive function: a review of the literature.
Topics: Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Epilepsy; Humans; Phenobarbital; Phenytoin | 1987 |
[Neurotraumatology and post-traumatic epilepsy. Prevention, treatment and long-term follow-up. Barbexaclone + phenobarbital (maliasin) versus diphenylhydantoin, phenobarbital, primidone, carbamazepine].
Topics: Adolescent; Adult; Anticonvulsants; Brain Injuries; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1987 |
[Status epilepticus in childhood].
Topics: Brain; Child; Child, Preschool; Diazepam; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Male; Phenobarbital; Phenytoin; Status Epilepticus; Suppositories | 1986 |
Therapeutic drug monitoring in pediatric acute drug intoxications.
Topics: Acetaminophen; Alcoholic Intoxication; Antidepressive Agents, Tricyclic; Child; Humans; Iron; Kinetics; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Poisoning; Salicylates; Salicylic Acid; Theophylline | 1985 |
Sulindac hepatotoxicity: a case report and review.
Topics: Acetaminophen; Adolescent; Adult; Aged; Animals; Child; Drug Interactions; Enzyme Induction; Ethanol; Female; Humans; Indenes; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Propionates; Sulindac | 1985 |
Febrile seizures: emergency department diagnosis and treatment.
Topics: Blood Cell Count; Blood Glucose; Child, Preschool; Counseling; Diagnosis, Differential; Diazepam; Drug Combinations; Electroencephalography; Female; Fever; Hospitalization; Humans; Hypoglycemia; Infant; Infusions, Parenteral; Injections, Intramuscular; Male; Meningitis; Phenobarbital; Phenytoin; Recurrence; Risk; Seizures; Sepsis; Sex Factors; Spinal Puncture | 1985 |
Pharmacokinetics of anti-epileptic drugs in the dog: a review.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Clonazepam; Diazepam; Dog Diseases; Dogs; Epilepsy; Ethosuximide; Kinetics; Phenobarbital; Phenytoin; Primidone; Species Specificity; Trimethadione; Valproic Acid | 1985 |
Biochemical and genetic factors regulating dilantin metabolism in man.
Topics: Aminosalicylic Acids; Animals; Ataxia; Cats; Chlordan; Cycloserine; DDT; Dicumarol; Disulfiram; Enzyme Induction; Female; Genetics, Medical; Humans; Intestinal Absorption; Isoniazid; Kinetics; Liver Diseases; Male; Metabolism; Microsomes, Liver; Nystagmus, Pathologic; Pedigree; Pharmacogenetics; Phenobarbital; Phenytoin; Rats; Thiazines | 1971 |
Utility of clinical chemical determinations of drug concentrations in biological fluids.
Topics: Adult; Allopurinol; Antipyrine; Ataxia; Chemistry, Clinical; Chromatography, Gas; Coffee; Desipramine; Dicumarol; Drug Antagonism; Drug Synergism; Ethanol; Female; Fluorometry; Half-Life; Humans; Iatrogenic Disease; Male; Mental Disorders; Metabolism; Methods; Middle Aged; Morphine; Nortriptyline; Nystagmus, Pathologic; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Smoking; Spectrophotometry; Twins; Ultraviolet Rays | 1971 |
Pharmacogenetics: defective enzymes in relation to reactions to drugs.
Topics: Acetylation; Cholinesterases; Coumarins; Dicumarol; Dose-Response Relationship, Drug; Female; Genetic Code; Genetic Diseases, Inborn; Glucosephosphate Dehydrogenase Deficiency; Humans; Isoniazid; Male; Metabolism, Inborn Errors; Pharmacogenetics; Phenacetin; Phenobarbital; Phenytoin; Succinylcholine | 1972 |
Febrile convulsions. A reappraisal.
Topics: Age Factors; Animals; Animals, Newborn; Body Temperature; Brain; Brain Damage, Chronic; Child, Preschool; Disease Models, Animal; Diseases in Twins; Dysentery; Electroencephalography; Epilepsy; Female; Fever; Genes, Dominant; Humans; Hypoglycemia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infections; Intellectual Disability; Male; Muscle Spasticity; Phenobarbital; Phenytoin; Prognosis; Seizures; Sex Factors; Sound | 1973 |
Anticonvulsants, folic acid, and epilepsy.
Topics: Anemia, Macrocytic; Animals; Anticonvulsants; Blood-Brain Barrier; Chemical Phenomena; Chemistry; Epilepsies, Partial; Epilepsy; Folic Acid; Humans; Leucovorin; Mice; Phenobarbital; Phenytoin; Primidone; Rabbits; Rats; Seizures | 1973 |
Usefulness of blood levels of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines | 1974 |
Diagnosis and treatment of epilepsy: overview and general principles.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Histamine H1 Antagonists; Humans; Hydantoins; Hypnotics and Sedatives; Infant, Newborn; Myoclonus; Phenobarbital; Phenytoin; Primidone; Sleep | 1974 |
Toxic hepatic porphyrias.
Topics: Alcoholism; Antifungal Agents; Chemical and Drug Induced Liver Injury; Chlorpropamide; Hexachlorocyclohexane; Humans; Liver; Phenobarbital; Phenytoin; Porphyrias; Sulfanilamides; Sulfones; Tolbutamide; Turkey | 1968 |
Interaction of drugs with thyroid hormone binding sites.
Topics: Binding Sites; Blood Proteins; Cell Nucleus; Drug Interactions; Endoplasmic Reticulum; Graves Disease; Humans; Kinetics; Liver; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Thyroid Hormones; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1973 |
[Epilepsy in children].
Topics: Child; Child, Preschool; Electroencephalography; Epilepsy; Epilepsy, Absence; Fever; Humans; Infant; Phenobarbital; Phenytoin; Seizures; Spasms, Infantile | 1974 |
Pharmacoligic prophylaxis of posttraumatic epilepsy. A review.
Topics: Accidents, Traffic; Adolescent; Adult; Animals; Anticonvulsants; Drug Therapy, Combination; Epilepsy, Post-Traumatic; Follow-Up Studies; Humans; Military Medicine; Neurons; Phenobarbital; Phenytoin; Vietnam | 1972 |
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Electroshock; Epilepsy; Ethosuximide; Humans; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Seizures; Trimethadione; Urea | 1969 |
Effects of tetanization on transmitter dynamics.
Topics: Acetazolamide; Acetylcholine; Action Potentials; Animals; Biological Transport; Carbon Dioxide; Cell Membrane Permeability; Epilepsy; Ganglia, Autonomic; Humans; Mathematics; Myelin Sheath; Neuromuscular Junction; Phenobarbital; Phenytoin; Reflex, Monosynaptic; Spinal Cord; Synapses; Synaptic Transmission; Time Factors | 1969 |
[Calcium metabolism disorders in antiepileptic therapy].
Topics: Animals; Anticonvulsants; Bone Diseases; Calcium; Calcium Metabolism Disorders; Cholecalciferol; Enzyme Induction; Epilepsy; Humans; Intestinal Absorption; Liver; Phenobarbital; Phenytoin; Rats; Swine | 1973 |
Vitamin D and rickets.
Topics: Acidosis, Renal Tubular; Animals; Bone and Bones; Bone Neoplasms; Calcification, Physiologic; Dihydroxycholecalciferols; Fanconi Syndrome; Humans; Hypophosphatemia, Familial; Kidney Failure, Chronic; Malabsorption Syndromes; Phenobarbital; Phenytoin; Rickets; Vitamin D | 1973 |
A basic approach to the understanding of seizures and the mechanism of action and metabolism of anticonvulsants.
Topics: Acetylcholine; Aminobutyrates; Anticonvulsants; Calcium; Cell Membrane Permeability; Depression, Chemical; Diazepam; Epilepsy; Ethosuximide; Humans; Membrane Potentials; Mephobarbital; Neural Inhibition; Neurons; Phenobarbital; Phenytoin; Primidone; Seizures; Stimulation, Chemical; Synapses; Synaptic Transmission | 1973 |
Toxic effects of anticonvulsants: general principles.
Topics: Adrenocorticotropic Hormone; Adult; Anticonvulsants; Benzodiazepinones; Body Surface Area; Body Weight; Carbamazepine; Child; Chlorobenzenes; Diagnosis, Differential; Diazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Half-Life; Humans; Nitro Compounds; Phenobarbital; Phenytoin; Primidone; Succinimides; Tranquilizing Agents; Trimethadione | 1974 |
Disordered calcium metabolism during anticonvulsant treatment.
Topics: Adolescent; Animals; Anticonvulsants; Biliary Tract; Bone Diseases; Calcium; Child; Cholecalciferol; Enzyme Induction; Epilepsy; Humans; Intestinal Absorption; Kidney; Liver; Metabolic Diseases; Phenobarbital; Phenytoin; Tritium; Vitamin D; Vitamin D Deficiency | 1973 |
The management of children with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsy; Ethosuximide; Humans; Infant; Infant, Newborn; Phenobarbital; Phenytoin; Primidone; Thiazines | 1970 |
Join the microsomal bandwagon.
Topics: Age Factors; Animals; Anthracenes; Carbon Disulfide; Dichlorodiphenyldichloroethane; Endoplasmic Reticulum; Enzyme Induction; Female; Hepatomegaly; Male; Microsomes, Liver; NADP; Phenobarbital; Phenytoin; Phospholipids; Protein Biosynthesis; Rats; Sex Factors; Steroids; Testosterone; Transferases | 1970 |
Adverse hematologic effects of drugs.
Topics: Anemia, Hemolytic; Anemia, Macrocytic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Aspirin; Blood Platelet Disorders; Drug-Related Side Effects and Adverse Reactions; Female; Glucosephosphate Dehydrogenase Deficiency; Hematologic Diseases; Hematopoiesis; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Infant, Newborn; Infant, Newborn, Diseases; Phenobarbital; Phenytoin; Pregnancy; Primidone; Serum Sickness; Splenomegaly; Thrombocytopenia; Tranquilizing Agents | 1972 |
Digitalis toxicity: drug interactions promoting toxicity and the management of toxicity.
Topics: Adrenergic beta-Antagonists; Anesthetics; Anticholesteremic Agents; Arrhythmias, Cardiac; Cathartics; Digitalis Glycosides; Digitoxin; Digoxin; Diuretics; Drug Interactions; Heart Conduction System; Heart Rate; Humans; Intestinal Absorption; Ion Exchange Resins; Lidocaine; Liver Circulation; Phenobarbital; Phenytoin; Potassium; Protein Binding | 1972 |
Pharmacology of anticonvulsants.
Topics: Animals; Anticonvulsants; Child; Drug Interactions; Electroencephalography; Ethosuximide; Half-Life; Humans; Liver; Mephobarbital; Phenobarbital; Phenytoin; Primidone | 1972 |
Epilepsy.
Topics: Animals; Brain; Carbamazepine; Diet Therapy; Epilepsy; Humans; Phenobarbital; Phenytoin | 1972 |
Halothane anesthesia and hepatitis in a high-risk population.
Topics: Chemical and Drug Induced Liver Injury; Chlorpromazine; Diazepam; Enzyme Induction; Halothane; Humans; Liver; Microsomes, Liver; Phenobarbital; Phenytoin; Postoperative Complications; Reserpine; Thioridazine; Time Factors | 1973 |
Recent progress in epilepsy. Diagnostic procedures and treatment.
Topics: Anticonvulsants; Brain Neoplasms; Diazepam; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Humans; Mephobarbital; Phenobarbital; Phenytoin; Psychosurgery; United States | 1973 |
Cerebrospinal folate levels in epileptics and their response to folate therapy.
Topics: Anticonvulsants; Blood-Brain Barrier; Clinical Trials as Topic; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Tetrahydrofolates; Vitamin B 12 | 1974 |
Epilepsy in the adolescent.
Topics: Acetazolamide; Adolescent; Age Factors; Alcoholic Intoxication; Amphetamine; Anticonvulsants; Attitude to Health; Carbamazepine; Cerebral Cortex; Contraceptives, Oral; Drug Interactions; Electroencephalography; Epilepsy; Female; Humans; Lysergic Acid Diethylamide; Male; Phenobarbital; Phenytoin; Psychology; Puberty; Substance-Related Disorders | 1974 |
Anticonvulsant pharmacokinetics.
Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Drug Interactions; Endoplasmic Reticulum; Humans; Hydrocortisone; Kinetics; Nucleoproteins; Phenobarbital; Phenylbutazone; Phenytoin; Protein Binding; Salicylates | 1974 |
The treatment of status epilepticus.
Topics: Anti-Bacterial Agents; Anticonvulsants; Barbiturates; Brain Edema; Central Nervous System Diseases; Child; Child, Preschool; Clothing; Diazepam; Emergencies; Epilepsy; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Injections, Intravenous; Lung Diseases; Oxygen Inhalation Therapy; Paraldehyde; Phenobarbital; Phenytoin; Recurrence | 1974 |
The use of blood levels of antiepileptic drugs in clinical practice.
Topics: Administration, Oral; Adult; Anticonvulsants; Biopharmaceutics; Carbamazepine; Child; Drug Tolerance; Epilepsy; Ethosuximide; Humans; Injections, Intramuscular; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Sleep; Time Factors | 1974 |
Pharmacodynamic and pharmacokinetic measurements of antiepileptic drugs.
Topics: Anticonvulsants; Chromatography, Gas; Dose-Response Relationship, Drug; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1974 |
Anticonvulsant drugs. II. Clinical pharmacological and therapeutic aspects.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Blood Coagulation Disorders; Cerebellum; Drug Interactions; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Seizures | 1972 |
Laboratory evaluation of antiepileptic drugs. Review of laboratory methods.
Topics: Animals; Anticonvulsants; Biological Assay; Brain Injuries; Diagnosis; Electroconvulsive Therapy; Electroshock; Humans; Methionine Sulfoximine; Methods; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Seizures; Strychnine; Thiosemicarbazones; Trimethadione; Urea | 1969 |
Factors influencng the rate of metabolism of steroid hormones in man.
Topics: Aldosterone; Androgens; Barbiturates; DDT; Dichlorodiphenyldichloroethane; Estradiol; Estrogens; Hormones; Humans; Hydrocortisone; Metabolism; Microsomes, Liver; Phenobarbital; Phenytoin; Progesterone; Protein Binding; Steroids; Testosterone; Thyroxine | 1971 |
Osteomalacia and anticonvulsant drugs.
Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Epilepsy; Folic Acid; Humans; Liver; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Vitamin D | 1971 |
The effects of CNS active drugs on the metabolism of steroids in man.
Topics: 17-Hydroxycorticosteroids; Androsterone; Animals; Barbiturates; Desoxycorticosterone; Estradiol; Etiocholanolone; Female; Guinea Pigs; Humans; Hydrocortisone; Ketosteroids; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Pregnanes; Progesterone; Rats; Testosterone | 1969 |
[General review of the present therapy of epilepsy].
Topics: Anticonvulsants; Barbiturates; Chlordiazepoxide; Diazepam; Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Succinimides | 1971 |
[Drug therapy of epilepsy].
Topics: Epilepsy; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Trimethadione; Urea | 1967 |
Effects of drug-drug and drug-food interaction on drug levels and performance in man.
Topics: Alcohol Drinking; Amphetamine; Animals; Animals, Laboratory; Behavior; Diet; Drug Interactions; Environment; Environmental Exposure; Environmental Health; Enzyme Induction; Enzyme Inhibitors; Enzymes; Ethanol; Humans; Hydrogen-Ion Concentration; Nicotine; Nutritional Physiological Phenomena; Phenobarbital; Phenytoin; Placenta; Psychopharmacology; Smoking | 1970 |
[Advance and clinic of antiepileptic drugs (author's transl)].
Topics: Animals; Anticonvulsants; Benzodiazepines; Brain; Carbamazepine; Epilepsy; Humans; Ion Channels; Mice; Neurotransmitter Agents; Phenobarbital; Phenytoin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Valproic Acid | 1981 |
Review of cimetidine drug interactions.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Anti-Bacterial Agents; Benzodiazepines; Cimetidine; Diet; Drug Interactions; Glucose; Guanidines; Histamine H1 Antagonists; Humans; Imidazoles; Insulin; Ketoconazole; Metoclopramide; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Piperazines; Propantheline | 1983 |
Theophylline reassessed.
Topics: Acidosis; Aging; Allopurinol; Animals; Anti-Bacterial Agents; Breast Feeding; Bronchodilator Agents; Caffeine; Contraceptives, Oral; Cooking; Cystic Fibrosis; Drug Interactions; Erythromycin; Female; Heart Diseases; Histamine H2 Antagonists; Humans; Hypoxia; Infections; Kinetics; Liver Diseases; Lung Diseases, Obstructive; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Respiration Disorders; Sleep; Smoking; Theophylline | 1984 |
The effects of drugs on the distribution and metabolism of thyroid hormones.
Topics: Animals; Antithyroid Agents; Carbamazepine; Carcinogens; Female; Heparin; Hormones; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Propranolol; Salicylates; Thyroid Hormones; Thyroxine-Binding Proteins | 1981 |
Effects of some clinically encountered drugs on steroid synthesis and degradation.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Drug Interactions; Ethanol; Fetus; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Hydrocortisone; Hydroxycholecalciferols; Liver; Metyrapone; Mitotane; Phenobarbital; Phenytoin; Rifampin; Spironolactone; Steroids | 1980 |
Reassessment of the concept of a therapeutic range of anticonvulsant plasma levels.
Topics: Anticonvulsants; Binding Sites; Brain Chemistry; Carbamazepine; Drug Therapy, Combination; Genetic Variation; Half-Life; Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Time Factors | 1983 |
Dural sinus and cerebral venous thrombosis.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Intracranial Embolism and Thrombosis; Male; Middle Aged; Phenobarbital; Phenytoin; Sinus Thrombosis, Intracranial | 1983 |
Seizures and seizure-like states in the child: an approach to emergency management.
Topics: Anesthesia, General; Child; Child, Preschool; Diagnosis, Differential; Diazepam; Emergencies; Humans; Infant; Lidocaine; Lorazepam; Paraldehyde; Phenobarbital; Phenytoin; Seizures; Sleep Wake Disorders; Status Epilepticus; Syncope | 1983 |
Diagnosis and treatment of epilepsy.
Topics: Automatism; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Ethosuximide; Humans; Muscle Tonus; Phenobarbital; Phenytoin; Primidone; Telemetry; Valproic Acid | 1983 |
Final adult height of patients with epilepsy.
Topics: Adolescent; Adult; Age Factors; Body Height; Epilepsies, Partial; Epilepsy; Epilepsy, Tonic-Clonic; Female; Growth Disorders; Humans; Male; Phenobarbital; Phenytoin; Social Class | 1983 |
Therapy for status epilepticus.
Topics: Acetazolamide; Anesthesia; Anticonvulsants; Barbiturates; Chlormethiazole; Clonazepam; Diazepam; Ethosuximide; Humans; Lidocaine; Lorazepam; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus; Valproic Acid | 1983 |
The clinical pharmacology of antiepileptic drugs.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Half-Life; Humans; Intestinal Absorption; Kidney; Kidney Diseases; Kinetics; Liver Diseases; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Tissue Distribution; Trimethadione; Valproic Acid | 1984 |
Interactions between anticonvulsants and other commonly prescribed drugs.
Topics: Analgesics; Anti-Infective Agents; Anticoagulants; Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Drug Interactions; Humans; Intestinal Absorption; Kinetics; Phenobarbital; Phenytoin; Primidone; Protein Binding; Psychotropic Drugs; Succinimides; Sulfonamides; Tissue Distribution; Valproic Acid | 1984 |
Clinical pharmacokinetics of antiepileptic drugs in adults.
Topics: Adult; Aging; Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Disease; Ethosuximide; Female; Humans; Kinetics; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva; Valproic Acid | 1980 |
Pharmacological principles in the long-term treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Kinetics; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Succinimides; Valproic Acid | 1981 |
[The post-traumatic epilepsy (author's transl)].
Topics: Brain Concussion; Brain Injuries; Brain Neoplasms; Carbamazepine; Diagnostic Errors; Electroencephalography; Ependymoma; Epilepsy, Post-Traumatic; Humans; Phenobarbital; Phenytoin; Primidone; Skull | 1981 |
The epileptic mother and her child.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Fetal Blood; Humans; Infant, Newborn; Maternal-Fetal Exchange; Milk, Human; Phenobarbital; Phenytoin; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Protein Binding; Status Epilepticus; Valproic Acid | 1982 |
Antiepileptic therapeutic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
Valproic acid: interactions with phenytoin and phenobarbital.
Topics: Binding, Competitive; Drug Interactions; Half-Life; Humans; Kinetics; Phenobarbital; Phenytoin; Protein Binding; Seizures; Valproic Acid | 1982 |
Use of antiepileptic drugs in the presence of liver and kidney diseases: a review.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Half-Life; Humans; Kidney Diseases; Kinetics; Liver Diseases; Phenobarbital; Phenytoin; Valproic Acid | 1982 |
Drug interactions with valproic acid.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Fatty Acids, Nonesterified; Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Salicylates; Valproic Acid | 1982 |
The expanding role of microsomal enzyme induction, and its implications for clinical chemistry.
Topics: Acetaminophen; Alcoholism; Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Electron Transport; Energy Intake; Enzyme Induction; Epilepsy; Female; Humans; Male; Microsomes, Liver; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Smoking; Tolbutamide; Warfarin | 1980 |
Adverse antibiotic drug interactions.
Topics: Aminosalicylic Acid; Antacids; Anti-Bacterial Agents; Biological Availability; Contraceptives, Oral; Digitoxin; Drug Interactions; Gastrointestinal Motility; Humans; Hydrogen-Ion Concentration; Kidney; Metals; Phenobarbital; Phenytoin; Rifampin; Sulfonamides; Tetracyclines; Warfarin | 1980 |
Seizure disorders.
Topics: Animals; Cat Diseases; Cats; Diagnosis, Differential; Diazepam; Dog Diseases; Dogs; Epilepsy; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Recurrence; Seizures; Succinimides | 1980 |
An overview of perinatal clinical pharmacology.
Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digoxin; Female; Fetus; Furosemide; Gentamicins; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Penicillins; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Tetracycline; Theophylline | 1981 |
Antiepileptic drugs and mechanisms of epileptogenesis. A review.
Topics: Animals; Anticonvulsants; Cats; Cerebral Cortex; Epilepsy; Phenobarbital; Phenytoin; Receptors, GABA; Sodium Channels | 1995 |
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder; Carbamazepine; Child; Child Behavior Disorders; Child, Preschool; Clonidine; Clozapine; Depressive Disorder; Dose-Response Relationship, Drug; Feeding and Eating Disorders; Fluoxetine; Humans; Imipramine; Lithium; Mutism; Obsessive-Compulsive Disorder; Phenobarbital; Phenytoin; Phobic Disorders; Schizophrenia; Sleep Wake Disorders; Tranquilizing Agents | 1995 |
Pregnancy, teratogenesis, and epilepsy.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Epilepsy; Female; Fetus; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 1994 |
Standard approach to antiepileptic drug treatment in the United Kingdom.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Prognosis; United Kingdom; Valproic Acid | 1994 |
Pharmacologic intervention and treatment of childhood seizure disorders: relative efficacy and safety of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Child; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Humans; Mice; Phenobarbital; Phenytoin; Treatment Outcome; Valproic Acid | 1994 |
Treatment of convulsive status epilepticus. Recommendations of the Epilepsy Foundation of America's Working Group on Status Epilepticus.
Topics: Benzodiazepines; Humans; Morbidity; Phenobarbital; Phenytoin; Resuscitation; Spinal Puncture; Status Epilepticus | 1993 |
Valproate-induced coma: case report and literature review.
Topics: Ammonia; Coma; Epilepsy, Complex Partial; Female; Humans; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1993 |
Treatment of status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Diazepam; Humans; Phenobarbital; Phenytoin; Status Epilepticus | 1993 |
Localization and characterization of cytochrome P450 in the brain. In vivo and in vitro investigations on phenytoin- and phenobarbital-inducible isoforms.
Topics: Animals; Brain; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Isoenzymes; Liver; Mice; Phenobarbital; Phenytoin; Rats | 1995 |
Parenteral antiepileptic/anticonvulsant drugs.
Topics: Anticonvulsants; Epilepsy; Humans; Infusions, Parenteral; Phenobarbital; Phenytoin | 1996 |
Adverse effects of established and new antiepileptic drugs: an attempted comparison.
Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Nervous System Diseases; Oxcarbazepine; Phenobarbital; Phenytoin; Sleep Stages; Vigabatrin | 1995 |
Optimisation of antiepileptic drug therapy. The importance of serum drug concentration monitoring.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; Phenobarbital; Phenytoin | 1996 |
Clinically significant pharmacokinetic drug interactions with carbamazepine. An update.
Topics: Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Carbamazepine; Drug Interactions; Ethosuximide; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Valproic Acid | 1996 |
Anticonvulsant hypersensitivity syndrome.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Drug Interactions; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Syndrome | 1997 |
A meta-analytic review of the preventive treatment of recurrences of febrile seizures.
Topics: Anticonvulsants; Chi-Square Distribution; Child; Diazepam; Drug Administration Schedule; Fever; Humans; Odds Ratio; Phenobarbital; Phenytoin; Pyridoxine; Randomized Controlled Trials as Topic; Recurrence; Risk Assessment; Seizures, Febrile; Valproic Acid | 1997 |
Antiepileptic drug review: part 1.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Drug Interactions; Half-Life; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1998 |
Anticonvulsant therapy in small animals.
Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid | 1998 |
Standards of laboratory practice: antiepileptic drug monitoring. National Academy of Clinical Biochemistry.
Topics: Anticonvulsants; Blood Specimen Collection; Carbamazepine; Drug Interactions; Drug Monitoring; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Valproic Acid | 1998 |
A mechanistic approach to antiepileptic drug interactions.
Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 1998 |
Antiepileptic drug hypersensitivity syndrome.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross Reactions; Diagnosis, Differential; Drug Hypersensitivity; Epilepsy; Exanthema; Humans; Incidence; Male; Phenobarbital; Phenytoin; Primidone; Syndrome | 1998 |
Population pharmacokinetics of lamotrigine adjunctive therapy in adults with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Phenytoin; Primidone; Randomized Controlled Trials as Topic; Retrospective Studies; Triazines | 1999 |
Management approaches to prolonged seizures and status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Diazepam; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Propofol; Seizures; Status Epilepticus; Treatment Outcome | 1999 |
Monostars: an aid to choosing an antiepileptic drug as monotherapy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Practice Patterns, Physicians'; Triazines; Valproic Acid; Vigabatrin | 1999 |
Therapeutic safety monitoring: what to look for and when to look for it.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2000 |
Treatment of status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Child; Humans; Patient Compliance; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Recurrence; Status Epilepticus | 2000 |
Status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Midazolam; Phenobarbital; Phenytoin; Propofol; Status Epilepticus; Valproic Acid | 2001 |
Treatment of status epilepticus in children.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Child; Humans; Phenobarbital; Phenytoin; Prevalence; Status Epilepticus | 2001 |
Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials.
Topics: Anticonvulsants; Brain Diseases; Brain Injuries; Carbamazepine; Controlled Clinical Trials as Topic; Diazepam; Epilepsy; Humans; Lorazepam; Models, Statistical; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Risk; Seizures; Treatment Outcome; Valproic Acid | 2001 |
Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalized onset tonic-clonic seizures.
Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy, Generalized; Humans; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures | 2001 |
Seizures in the newborn.
Topics: Anticonvulsants; Benzodiazepines; Diazepam; Electroencephalography; Humans; Infant, Newborn; Neonatal Screening; Phenobarbital; Phenytoin; Seizures | 2001 |
The current state of treatment of status epilepticus.
Topics: Animals; Anticonvulsants; Benzodiazepines; Brain; Electroencephalography; Female; GABA Modulators; Humans; Midazolam; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Status Epilepticus; Treatment Outcome; Valproic Acid | 2002 |
Neonatal seizures and their treatment.
Topics: Anticonvulsants; Brain; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Neuronal Plasticity; Phenobarbital; Phenytoin; Prognosis; Seizures | 2003 |
New management strategies in the treatment of status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Emergency Medical Services; Humans; Phenobarbital; Phenytoin; Status Epilepticus; United States; Valproic Acid | 2003 |
IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY.
Topics: Animals; Benzopyrenes; Cyclizine; Dicumarol; Diphenhydramine; Dogs; Drug Therapy; Enzyme Induction; Enzymes; Glutethimide; Hexobarbital; Liver; Meprobamate; Metabolism; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Probenecid; Rats; Research; Tolbutamide; Toxicology; Zoxazolamine | 1964 |
Management of seizures in children with falciparum malaria.
Topics: Anticonvulsants; Child; Diazepam; Emergency Treatment; Humans; Malaria, Cerebral; Malaria, Falciparum; Phenobarbital; Phenytoin; Seizures | 2004 |
Acetaminophen misconceptions.
Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Drug Interactions; Humans; Liver; Phenobarbital; Phenytoin | 2004 |
Phenobarbital for the treatment of epilepsy in the 21st century: a critical review.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Cost-Benefit Analysis; Developing Countries; Drug Costs; Epilepsy; Female; Global Health; Humans; Infant, Newborn; Male; Meta-Analysis as Topic; Middle Aged; Neurotoxicity Syndromes; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Status Epilepticus; Treatment Outcome | 2004 |
Cancer risk in people with epilepsy: the role of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Neoplasms; Phenobarbital; Phenytoin; Rats; Risk Factors; Valproic Acid | 2005 |
Seizure prophylaxis in patients with brain tumors: a meta-analysis.
Topics: Anticonvulsants; Brain Neoplasms; Comorbidity; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Incidence; Male; Odds Ratio; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Risk Assessment; Seizures; Treatment Failure; Valproic Acid | 2004 |
Mechanisms regulating toxicant disposition to the embryo during early pregnancy: an interspecies comparison.
Topics: Animals; Biological Transport; Carbamazepine; Embryonic Development; Female; Humans; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Placenta; Pregnancy; Rabbits; Rats; Salicylic Acid; Species Specificity; Teratogens; Toxicity Tests; Tretinoin; Valproic Acid; Yolk Sac | 2004 |
Status epilepticus: an evidence based guide.
Topics: Anticonvulsants; Chronic Disease; Critical Care; Drug Administration Routes; Emergency Treatment; Evidence-Based Medicine; Humans; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Prognosis; Randomized Controlled Trials as Topic; Referral and Consultation; Status Epilepticus | 2005 |
Anticonvulsant therapy for status epilepticus.
Topics: Anticonvulsants; Diazepam; Humans; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Status Epilepticus | 2005 |
[Update on current care guidelines. Prolonged epileptic attack].
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Diazepam; Drug Therapy, Combination; Electroencephalography; Emergency Medical Services; Female; Finland; Humans; Infusions, Intravenous; Lorazepam; Male; Monitoring, Physiologic; Phenobarbital; Phenytoin; Risk Assessment; Severity of Illness Index; Status Epilepticus; Survival Rate; Time Factors; Treatment Outcome | 2006 |
Therapeutic monitoring of antiepileptic drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 2007 |
Pharmacokinetics of antiepileptic drugs in elderly nursing home residents.
Topics: Aged; Anticonvulsants; Carbamazepine; Humans; Nursing Homes; Phenobarbital; Phenytoin; Valproic Acid | 2007 |
Anticonvulsant therapy for status epilepticus.
Topics: Anticonvulsants; Diazepam; Humans; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Status Epilepticus | 2007 |
[Neuromuscular disorders caused by adverse effects of antiepileptics].
Topics: Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Neuromuscular Diseases; Phenobarbital; Phenytoin; Topiramate; Valproic Acid; Zonisamide | 2007 |
Antiepileptic drugs as human teratogens.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2008 |
[Caffeine and antiepileptic drugs: experimental and clinical data].
Topics: Animals; Anticonvulsants; Caffeine; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Humans; Lamotrigine; Mice; Nipecotic Acids; Phenobarbital; Phenytoin; Seizures; Tiagabine; Triazines; Valproic Acid | 2007 |
Preventing and treating posttraumatic seizures: the human experience.
Topics: Animals; Anticonvulsants; Brain Injuries; Drug Evaluation, Preclinical; Drug Therapy, Combination; Electroencephalography; Epilepsy, Post-Traumatic; Head Injuries, Penetrating; Hematoma, Subdural; Humans; Phenobarbital; Phenytoin; Prognosis; Seizures | 2009 |
Traditional Chinese medicine for epilepsy.
Topics: Anticonvulsants; Drugs, Chinese Herbal; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Medicine, Chinese Traditional; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Valproic Acid | 2009 |
What is the relative value of the standard anticonvulsants: Phenytoin and fosphenytoin, phenobarbital, valproate, and levetiracetam?
Topics: Anticonvulsants; Benzodiazepines; Humans; Levetiracetam; Phenobarbital; Phenytoin; Piracetam; Prodrugs; Status Epilepticus; Treatment Outcome; Valproic Acid | 2009 |
Side effects of phenobarbital in epilepsy: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Child; Cognition Disorders; Cohort Studies; Cross-Over Studies; Data Collection; Data Interpretation, Statistical; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Randomized Controlled Trials as Topic; Research; Research Design; Treatment Outcome; Valproic Acid | 2011 |
The effects of antiepileptic drugs on oral health.
Topics: Alveolar Bone Loss; Anticonvulsants; Carbamazepine; Epilepsy; Gingival Hyperplasia; Humans; Oral Health; Phenobarbital; Phenytoin | 2011 |
Epilepsy meets cancer: when, why, and what to do about it?
Topics: Animals; Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Causality; Comorbidity; Drug Interactions; Humans; Meningeal Carcinomatosis; Phenobarbital; Phenytoin; Radiotherapy; Seizures | 2012 |
Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalised onset tonic-clonic seizures.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; Induction Chemotherapy; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Recurrence; Seizures; Time Factors; Valproic Acid | 2013 |
Antiepileptic drugs as prophylaxis for post-craniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2013 |
Seizures and intracranial hemorrhage.
Topics: Anticonvulsants; Carbamazepine; Congenital Abnormalities; Eclampsia; Epilepsy; Female; Folic Acid; Heparin; Humans; Infant, Newborn; Intracranial Hemorrhages; Lamotrigine; Monitoring, Physiologic; North America; Phenobarbital; Phenytoin; Pregnancy; Risk Factors; Seizures; Subarachnoid Hemorrhage; Triazines; Valproic Acid; Vitamin K | 2013 |
WITHDRAWN: Traditional Chinese medicine for epilepsy.
Topics: Anticonvulsants; Drugs, Chinese Herbal; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Medicine, Chinese Traditional; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Valproic Acid | 2014 |
Developmental neurotoxicity and anticonvulsant drugs: a possible link.
Topics: Animals; Anticonvulsants; Breast Feeding; Carbamazepine; Cognition Disorders; Developmental Disabilities; Female; Humans; Lamotrigine; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Triazines; Valproic Acid | 2014 |
[Treatment of status epilepticus].
Topics: Anesthesia, General; Diazepam; Drug Administration Routes; Evidence-Based Medicine; Humans; Hypothermia, Induced; Intensive Care Units; Midazolam; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Propofol; Status Epilepticus; Thiopental; Time Factors | 2014 |
Anticonvulsant therapy for status epilepticus.
Topics: Anticonvulsants; Diazepam; Humans; Injections, Intravenous; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Status Epilepticus | 2014 |
Antiepileptic drugs as prophylaxis for post-craniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2015 |
Drug-induced status epilepticus.
Topics: Animals; Anti-Bacterial Agents; Anticonvulsants; gamma-Aminobutyric Acid; Humans; Nipecotic Acids; Phenobarbital; Phenytoin; Status Epilepticus; Tiagabine | 2015 |
[Preconceptional and perinatal challenges of pregnancy in women with epilepsy].
Topics: Adult; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Parturition; Perinatal Care; Phenobarbital; Phenytoin; Piracetam; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Teratogens; Triazines; Valproic Acid | 2016 |
Prophylactic barbiturate use for the prevention of morbidity and mortality following perinatal asphyxia.
Topics: Anticonvulsants; Asphyxia Neonatorum; Barbiturates; Humans; Infant; Infant, Newborn; Infant, Premature; Neurodevelopmental Disorders; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Thiopental | 2016 |
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy.
Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide | 2016 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Levetiracetam; Phenobarbital; Phenytoin; Piracetam; Postoperative Complications; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2018 |
[Medicaments and oral healthcare. Proliferation of the gingiva].
Topics: Anticonvulsants; Carbamazepine; Cell Proliferation; Ethosuximide; Gingiva; Humans; Netherlands; Oral Hygiene; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 2018 |
Meta-analysis and cost-effectiveness of second-line antiepileptic drugs for status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Cost-Benefit Analysis; Decision Support Techniques; Humans; Lacosamide; Levetiracetam; Phenobarbital; Phenytoin; Status Epilepticus; Treatment Failure; Valproic Acid | 2019 |
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Levetiracetam; Phenobarbital; Phenytoin; Piracetam; Postoperative Complications; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2020 |
Use of Phenytoin, Phenobarbital Carbamazepine, Levetiracetam Lamotrigine and Valproate in Pregnancy and Breastfeeding: Risk of Major Malformations, Dose-dependency, Monotherapy vs Polytherapy, Pharmacokinetics and Clinical Implications.
Topics: Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2021 |
Efficacy and Safety of Phenobarbitone as First-Line Treatment for Neonatal Seizure: A Systematic Review and Meta-Analysis.
Topics: Anticonvulsants; Carbamazepine; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Seizures | 2021 |
Side effects of long-term oral anti-seizure drugs on thyroid hormones in patients with epilepsy: a systematic review and network meta-analysis.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Topiramate; Valproic Acid | 2022 |
COVID-19 and antiepileptic drugs: an approach to guide practices when nirmatrelvir/ritonavir is co-prescribed.
Topics: Anticonvulsants; Carbamazepine; Clobazam; COVID-19 Drug Treatment; Cytochrome P-450 CYP3A Inducers; Drug Interactions; Humans; Oxcarbazepine; Pentobarbital; Phenobarbital; Phenytoin; Ritonavir; Valproic Acid | 2022 |
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide | 2022 |
Treatment of benzodiazepine-resistant status epilepticus: Systematic review and network meta-analyses.
Topics: Adult; Anticonvulsants; Benzodiazepines; Child; Drug Resistance; Humans; Levetiracetam; Network Meta-Analysis; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Status Epilepticus; Treatment Outcome; Valproic Acid | 2022 |
[Paediatric status epilepticus].
Topics: Adult; Anesthetics; Anticonvulsants; Benzodiazepines; Child; Epilepsy; Humans; Ketamine; Lacosamide; Levetiracetam; Lidocaine; Phenobarbital; Phenytoin; Propofol; Seizures; Status Epilepticus; Topiramate; Valproic Acid | 2022 |
Anti-seizure medications for neonates with seizures.
Topics: Adolescent; Adult; Child; Epilepsy; Humans; Infant; Infant, Newborn; Levetiracetam; Phenobarbital; Phenytoin; Seizures | 2023 |
109 trial(s) available for phenytoin and phenobarbital
| Article | Year |
|---|---|
Evaluation of clorazepate (Tranxene) as an anticonvulsant--a pilot study.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Clorazepate Dipotassium; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsies, Partial; Female; Humans; Male; Phenobarbital; Phenytoin; Pilot Projects | 1979 |
One drug (phenytoin) in the treatment of epilepsy.
Topics: Adolescent; Adult; Aged; Drug Evaluation; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Placebos; Primidone; Time Factors | 1976 |
[Value of anticonvulsant level determination in the treatment of epilepsies].
Topics: Clinical Trials as Topic; Drug Administration Schedule; Epilepsy; Humans; Patient Dropouts; Phenobarbital; Phenytoin | 1977 |
[Experiences with sodium 2-propyl valerate (Depakine) in the treatment of epilepsy].
Topics: Adolescent; Adult; Aged; Carbamazepine; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy; Female; Humans; Hydrocephalus; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Spasms, Infantile; Valerates; Valproic Acid | 1977 |
Valproate sodium: a controlled clinical trial including monitoring of drug levels.
Topics: Adult; Child; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Placebos; Valerates; Valproic Acid | 1977 |
Clonazepam: its efficacy in association with phenytoin and phenobarbital in mental patients with generalized major motor seizures.
Topics: Benzodiazepinones; Clinical Trials as Topic; Clonazepam; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Mental Disorders; Phenobarbital; Phenytoin; Placebos | 1978 |
Sodium valproate, serum level and clinical effect in epilepsy: a controlled study.
Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Dimethadione; Dose-Response Relationship, Drug; Drug Evaluation; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1979 |
Phenytoin dosage in ambulant epileptic patients.
Topics: Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin | 1978 |
Paracetamol disposition in normal subjects and in patients treated with antiepileptic drugs.
Topics: Acetaminophen; Administration, Oral; Adult; Anticonvulsants; Biological Availability; Carbamazepine; Female; Humans; Injections, Intravenous; Male; Phenobarbital; Phenytoin; Primidone | 1979 |
Oral and intramuscular phenytoin.
Topics: Administration, Oral; Adult; Clinical Trials as Topic; Drug Administration Schedule; Epilepsy; Epilepsy, Temporal Lobe; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Phenobarbital; Phenytoin; Time Factors | 1976 |
[Treatment of status epilepticus with clonazepam].
Topics: Benzodiazepinones; Clinical Trials as Topic; Clonazepam; Diazepam; Drug Evaluation; Humans; Phenobarbital; Phenytoin; Status Epilepticus | 1976 |
[Changes in serum concentrations of calcium and inorganic phosphates and alkaline phosphatase activity due to anti-ipileptic treatment].
Topics: Adolescent; Adult; Alkaline Phosphatase; Calcium; Clinical Trials as Topic; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Phosphates | 1976 |
Carbamazepine in difficult to control epileptic out-patients.
Topics: Adolescent; Adult; Ambulatory Care; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Leukocyte Count; Middle Aged; Outpatient Clinics, Hospital; Phenobarbital; Phenytoin; Placebos | 1975 |
Plasma level and effect of carbamazepine in grand mal and psychomotor epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Middle Aged; Phenobarbital; Phenytoin | 1975 |
A controlled trial on clonazepam INN (Ro 5-4023, Rivotril (R)) in the treatment of focal epilepsy and secondary generalized grand mal epilepsy.
Topics: Adolescent; Adult; Aged; Benzodiazepinones; Child; Child, Preschool; Clinical Trials as Topic; Clonazepam; Drug Evaluation; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Placebos | 1975 |
A pilot study of oral vitamin D2 in epileptics on anticonvulsants.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Clinical Trials as Topic; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Ergocalciferols; Female; Humans; Male; Phenobarbital; Phenytoin; Pilot Projects; Placebos | 1975 |
The relation of anticonvulsant drug levels to complete seizure control.
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin | 1976 |
Controlled trial of sodium valproate in severe epilepsy.
Topics: Adult; Clinical Trials as Topic; Drug Evaluation; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Placebos; Valerates; Valproic Acid | 1975 |
The efficacy of carbamazepine combinations in epilepsy.
Topics: Adult; Biological Availability; Carbamazepine; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Time Factors | 1975 |
Interaction of phenytoin and primidone.
Topics: Adolescent; Adult; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1975 |
Analyses of the pattern of therapeutic drug monitoring in a university hospital laboratory. Suitability and performance of the CEDIA assays.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Cyclosporine; Digoxin; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy; Humans; Immunoenzyme Techniques; Pharmacokinetics; Phenobarbital; Phenytoin; Quality Control; Theophylline | 1992 |
Bromide treatment of pharmaco-resistant epilepsies with generalized tonic-clonic seizures: a clinical study.
Topics: Adolescent; Bromides; Child; Child, Preschool; Drug Resistance; Epilepsy, Tonic-Clonic; Female; Humans; Male; Phenobarbital; Phenytoin; Retrospective Studies | 1992 |
Comparative cognitive effects of anticonvulsants.
Topics: Adult; Anticonvulsants; Carbamazepine; Cognition; Epilepsy; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Phenobarbital; Phenytoin; Random Allocation; Statistics as Topic | 1990 |
Phenytoin and phenobarbital concentrations in serum: a comparison of Ames Seralyzer with GLC, TDX, and EMIT.
Topics: Chromatography, Gas; Humans; Immunoenzyme Techniques; Multicenter Studies as Topic; Phenobarbital; Phenytoin | 1989 |
Aspects of compliance: taking drugs and keeping clinic appointments.
Topics: Adolescent; Adult; Anticonvulsants; Appointments and Schedules; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Outpatient Clinics, Hospital; Patient Compliance; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1988 |
Treatment of status epilepticus: a prospective comparison of diazepam and phenytoin versus phenobarbital and optional phenytoin.
Topics: Adult; Aged; Clinical Trials as Topic; Diazepam; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prospective Studies; Random Allocation; Status Epilepticus | 1988 |
Results of a nationwide Veterans Administration Cooperative Study comparing the efficacy and toxicity of carbamazepine, phenobarbital, phenytoin, and primidone.
Topics: Adult; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1987 |
Progabide for refractory partial epilepsy: a controlled add-on trial.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Random Allocation | 1986 |
[Preventive treatment of convulsions in perinatal asphyxia].
Topics: Asphyxia Neonatorum; Double-Blind Method; Female; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Random Allocation; Seizures | 1987 |
Prednisolone and methylprednisolone kinetics in children receiving anticonvulsant therapy.
Topics: Adolescent; Anticonvulsants; Asthma; Biological Availability; Carbamazepine; Child; Half-Life; Humans; Methylprednisolone; Phenobarbital; Phenytoin; Prednisolone; Research Design | 1987 |
Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures.
Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsies, Partial; Epilepsy; Erectile Dysfunction; Female; Follow-Up Studies; Humans; Leukocyte Count; Lupus Vulgaris; Lymphoma; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Psychoses, Substance-Induced | 1985 |
Influence of folic acid on blood-phenytoin levels.
Topics: Adult; Anticonvulsants; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1971 |
Evaluation of albutoin as an antiepileptic drug.
Topics: Adolescent; Adult; Allyl Compounds; Analysis of Variance; Anticonvulsants; Appetite; Biopharmaceutics; Chromatography, Thin Layer; Clinical Trials as Topic; Drug Evaluation; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Female; Humans; Hydantoins; Male; Middle Aged; Nausea; Phenobarbital; Phenytoin; Placebos; Primidone; Spectrophotometry; Statistics as Topic; Thiohydantoins; Time Factors; Vomiting | 1974 |
"Anticonvulsant action" of vitamin D in epileptic patients? A controlled pilot study.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Calcium; Child; Clinical Trials as Topic; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Magnesium; Male; Phenobarbital; Phenytoin; Placebos; Primidone; Vitamin D | 1974 |
Carbamazepine for epilepsy. A controlled prospective evaluation.
Topics: Adult; Blood Cell Count; Bone Marrow Diseases; Carbamazepine; Clinical Trials as Topic; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Evaluation Studies as Topic; Female; Gastrointestinal Diseases; Humans; Leukopenia; Male; Middle Aged; Phenobarbital; Phenytoin; Placebos; Prospective Studies; Psychiatric Status Rating Scales | 1974 |
The effects of carbamazepine on patients with psychomotor epilepsy: results of a double-blind study.
Topics: Adolescent; Adult; Analysis of Variance; Behavior; Carbamazepine; Cerebral Cortex; Clinical Trials as Topic; Computers; Drug Evaluation; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Placebos; Telemetry | 1974 |
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Electroshock; Epilepsy; Ethosuximide; Humans; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Seizures; Trimethadione; Urea | 1969 |
Studies in hyperkinetic behavior. II. Laboratory and clinical evaluations of drug treatments.
Topics: Adolescent; Amphetamine; Animals; Anticonvulsants; Central Nervous System Stimulants; Child; Higher Nervous Activity; Humans; Locomotion; Methylphenidate; Mice; Movement Disorders; Phenobarbital; Phenytoin | 1967 |
Drug--interaction between sulthiame (Ospolot (R)) and phenytoin in the treatment of epilepsy.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Thiazines; Time Factors | 1969 |
Effect of chronic anticonvulsant therapy on serum 25-hydroxycalciferol levels in adults.
Topics: Adult; Alkaline Phosphatase; Anticonvulsants; Calcium; Clinical Trials as Topic; Epilepsy; Ergocalciferols; Female; Humans; Hydroxycholecalciferols; Hypocalcemia; Isoenzymes; Male; Phenobarbital; Phenytoin; Phosphates; Serum Albumin; Sunlight; Time Factors; Vitamin D | 1972 |
Diphenylhydantoin and phenobarbital in the relief of psychoneurotic symptoms. A controlled comparison.
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Clinical Trials as Topic; Conversion Disorder; Depression; Humans; Middle Aged; Neurotic Disorders; Obsessive-Compulsive Disorder; Phenobarbital; Phenytoin; Placebos | 1972 |
Length of treatment with anxiolytic sedatives and response to their sudden withdrawal.
Topics: Adolescent; Adult; Aged; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Male; Middle Aged; Neurotic Disorders; Outpatient Clinics, Hospital; Phenobarbital; Phenytoin; Placebos; Substance Withdrawal Syndrome; Time Factors | 1973 |
Folate therapy in epilepsy. A controlled study.
Topics: Clinical Trials as Topic; Cognition; Epilepsy; Evaluation Studies as Topic; Folic Acid; Humans; Leucovorin; Personality; Phenobarbital; Phenytoin; Primidone; Psychological Tests | 1973 |
A controlled trial on Ro 5-4023 (clonazepam) in the treatment of psychomotor epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Carbamazepine; Child; Chlorobenzenes; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Fatigue; Female; Humans; Male; Middle Aged; Nitro Compounds; Phenobarbital; Phenytoin; Placebos; Primidone; Time Factors | 1973 |
Difference in the central actions of phenytoin and phenobarbitone in man, measured by critical flicker fusion threshold.
Topics: Administration, Oral; Adult; Chromatography, Gas; Clinical Trials as Topic; Dose-Response Relationship, Drug; Flicker Fusion; Humans; Phenobarbital; Phenytoin; Placebos; Time Factors | 1973 |
Cerebrospinal folate levels in epileptics and their response to folate therapy.
Topics: Anticonvulsants; Blood-Brain Barrier; Clinical Trials as Topic; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Tetrahydrofolates; Vitamin B 12 | 1974 |
Renal insensitivity to frusemide caused by chronic anticonvulsant therapy.
Topics: Administration, Oral; Adult; Anticonvulsants; Clinical Trials as Topic; Diuresis; Drug Interactions; Drug Resistance; Epilepsy; Furosemide; Humans; Injections, Intravenous; Kidney; Kidney Tubules; Middle Aged; Phenobarbital; Phenytoin; Placebos; Time Factors | 1974 |
Incidence of anticonvulsant osteomalacia and effect of vitamin D: controlled therapeutic trial.
Topics: Adult; Aged; Alkaline Phosphatase; Anticonvulsants; Bone and Bones; Calcium; Creatinine; Epilepsy; Female; Humans; Male; Mathematics; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Placebos; Primidone; Radiometry; Vitamin D | 1973 |
Subnormal serum folate due to anticonvulsive therapy. A double-blind study of the effect of folic acid treatment in patients with drug-induced subnormal serum folates.
Topics: Adult; Anticonvulsants; Clinical Trials as Topic; Epilepsy; Erythrocyte Count; Female; Folic Acid; Hematocrit; Hemoglobinometry; Humans; Male; Phenobarbital; Phenytoin; Placebos; Primidone | 1970 |
Treatment of alcohol withdrawal syndromes.
Topics: Chloral Hydrate; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Drug Synergism; Ethanol; Humans; Injections, Intramuscular; Paraldehyde; Phenobarbital; Phenytoin; Placebos; Promazine; Psychoses, Alcoholic; Seizures; Substance Withdrawal Syndrome | 1971 |
A survey of 156 seizure patients in a general pediatric clinic.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy; Epilepsy, Absence; Female; Humans; Infant; Infant, Newborn; Male; Phenobarbital; Phenytoin | 1966 |
Diazepam ("Valium") in the control of status epilepticus.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Diazepam; Drug Synergism; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Male; Phenobarbital; Phenytoin | 1967 |
Effect of phenobarbital on hyperbilirubinemia, bile acid metabolism, and microsomal enzyme activity in chronic intrahepatic cholestasis of childhood.
Topics: Bile; Bile Acids and Salts; Bilirubin; Biopsy; Child; Child, Preschool; Cholestasis; Chronic Disease; Humans; Liver; Microsomes, Liver; Phenobarbital; Phenytoin; Rose Bengal | 1972 |
Relative anticonvulsant potency of primidone; a double blind comparison.
Topics: Clinical Trials as Topic; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1966 |
The influence of phenobarbital on the half-life of diphenylhydantoin in man.
Topics: Adolescent; Adult; Aged; Carbon Isotopes; Enzyme Induction; Epilepsy; Humans; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Phenytoin | 1969 |
Placebo-controlled study of phenobarbitone and phenytoin in the prophylaxis of febrile convulsions.
Topics: Age Factors; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Recurrence; Seizures, Febrile | 1981 |
Clorazepate and phenobarbital as antiepileptic drugs: a double-blind study.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Clinical Trials as Topic; Clorazepate Dipotassium; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Male; Nordazepam; Phenobarbital; Phenytoin; Psychological Tests | 1981 |
Single drug therapy for intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Epilepsy, Temporal Lobe; Humans; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1983 |
Historical perspective on the choice of antiepileptic drugs for the treatment of seizures in adults.
Topics: Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Epilepsy; History, 20th Century; Humans; Phenobarbital; Phenytoin; Primidone; Seizures | 1983 |
Controlled and comparative trials of valproate performed in Europe and Asia.
Topics: Adolescent; Adult; Asia; Carbamazepine; Child; Clinical Trials as Topic; Epilepsy; Europe; Humans; Phenobarbital; Phenytoin; Seizures, Febrile; Valproic Acid | 1984 |
Influence of therapeutic phenobarbital and phenytoin medication on the polygraphic sleep of patients with epilepsy.
Topics: Adolescent; Adult; Aged; Drug Interactions; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sleep; Sleep, REM | 1984 |
Influence of dextropropoxyphene on steady state serum levels and protein binding of three anti-epileptic drugs in man.
Topics: Adolescent; Adult; Aged; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Dextropropoxyphene; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding | 1980 |
The Cambridge glioma trial of misonidazole and radiation therapy with associated pharmacokinetic studies.
Topics: Brain Neoplasms; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Glioma; Head and Neck Neoplasms; Humans; Kinetics; Misonidazole; Phenobarbital; Phenytoin; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms | 1980 |
Kinetics of phenobarbital in normal subjects and epileptic patients.
Topics: Administration, Oral; Adult; Biological Availability; Carbamazepine; Epilepsy; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Phenobarbital; Phenytoin | 1982 |
Behavioural effects of phenobarbitone and phenytoin in small children.
Topics: Child Behavior Disorders; Female; Hospitalization; Humans; Infant; Male; Phenobarbital; Phenytoin; Seizures, Febrile | 1981 |
Comparative cognitive effects of phenobarbital, phenytoin, and valproate in healthy adults.
Topics: Adult; Cognition; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Phenobarbital; Phenytoin; Reference Values; Valproic Acid | 1995 |
Phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed adult epilepsy: a randomised comparative monotherapy trial.
Topics: Adolescent; Adult; Aged; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prospective Studies; Valproic Acid | 1995 |
Neonatal phenobarbital and phenytoin binding profiles.
Topics: Birth Weight; Female; Gestational Age; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Protein Binding; Seizures | 1994 |
Thiamine and folate treatment of chronic epileptic patients: a controlled study with the Wechsler IQ scale.
Topics: Adult; Brain; Double-Blind Method; Drug Therapy, Combination; Education; Electroencephalography; Epilepsy; Female; Folic Acid; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Thiamine; Vitamin B 12; Wechsler Scales | 1993 |
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo.
Topics: Administration, Oral; Adult; Antipyrine; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Ethosuximide; Humans; Liver; Lorazepam; Male; Oxidoreductases, N-Demethylating; Phenobarbital; Phenytoin; Quinidine; Rifampin; Smoking; Theophylline; Valproic Acid | 1993 |
Pharmacokinetic interaction of single doses of quinine and carbamazepine, phenobarbitone and phenytoin in healthy volunteers.
Topics: Administration, Oral; Adult; Carbamazepine; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Quinine | 1993 |
A comparison of the OPUS and TDx analysers for antiepileptic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Female; Fluorescence Polarization Immunoassay; Humans; Immunoassay; Male; Phenobarbital; Phenytoin; Regression Analysis; Reproducibility of Results; Valproic Acid | 1995 |
Randomised comparative monotherapy trial of phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed childhood epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Prospective Studies; Treatment Outcome; Valproic Acid | 1996 |
Assessment of drowsiness in epilepsy patients receiving chronic antiepileptic drug therapy.
Topics: Adult; Age Factors; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Psychiatric Status Rating Scales; Psychological Tests; Sleep Stages; Valproic Acid; Wakefulness | 1996 |
Systematic testing of medical intractability for carbamazepine, phenytoin, and phenobarbital or primidone in monotherapy for patients considered for epilepsy surgery.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Epilepsy; Follow-Up Studies; Humans; Infant; Middle Aged; Patient Selection; Phenobarbital; Phenytoin; Primidone; Quality of Life; Treatment Failure; Treatment Outcome | 1996 |
Effect of enzyme inducing anticonvulsants on ethosuximide pharmacokinetics in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Interactions; Enzyme Induction; Epilepsy; Ethosuximide; Female; Half-Life; Humans; Intestinal Absorption; Male; Middle Aged; Phenobarbital; Phenytoin | 1996 |
Antiepileptic drug treatment in pregnancy: drug side effects in the neonate and neurological outcome.
Topics: Anticonvulsants; Child; Drug Monitoring; Epilepsy; Female; Follow-Up Studies; Humans; Nervous System Diseases; Neurologic Examination; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Primidone; Valproic Acid | 1996 |
Peri-operative prophylaxis with phenytoin: dosage and therapeutic plasma levels.
Topics: Adult; Aged; Anticonvulsants; Cefazolin; Dexamethasone; Drug Interactions; Drug Therapy, Combination; Female; Humans; Intraoperative Care; Male; Mannitol; Middle Aged; Phenobarbital; Phenytoin; Postoperative Complications; Premedication; Ranitidine; Seizures; Supratentorial Neoplasms | 1996 |
Brainstem auditory evoked potentials in epileptics on different anti-epileptic drugs.
Topics: Acoustic Stimulation; Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Combinations; Epilepsy; Evoked Potentials, Auditory, Brain Stem; Female; Functional Laterality; Humans; Phenobarbital; Phenytoin | 1996 |
Serum concentrations of lamotrigine in epileptic patients: the influence of dose and comedication.
Topics: Adult; Age Factors; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Triazines; Valproic Acid | 1996 |
Comparison of phenobarbitone, phenytoin with sodium valproate: randomized, double-blind study.
Topics: Child; Child, Preschool; Epilepsy, Tonic-Clonic; Female; Humans; Phenobarbital; Phenytoin; Recurrence; Valproic Acid | 1996 |
Examination of stability of anticonvulsants in a protease solution and assay of anticonvulsants in hairs.
Topics: Anticonvulsants; Drug Stability; Endopeptidases; Gas Chromatography-Mass Spectrometry; Hair; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Solutions; Spectrophotometry, Ultraviolet | 1996 |
Randomised controlled trial to assess acceptability of phenobarbital for childhood epilepsy in rural India.
Topics: Adolescent; Anticonvulsants; Child; Child Behavior Disorders; Child, Preschool; Developing Countries; Epilepsies, Partial; Epilepsy, Generalized; Feasibility Studies; Female; Follow-Up Studies; Humans; India; Male; Phenobarbital; Phenytoin; Proportional Hazards Models; Rural Population; Time Factors; Treatment Outcome | 1998 |
Treatment of refractory status epilepticus with propofol: clinical and pharmacokinetic findings.
Topics: Adult; Aged; Barbiturates; Clinical Protocols; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypotension; Infusion Pumps; Infusions, Intravenous; Male; Middle Aged; Phenobarbital; Phenytoin; Propofol; Status Epilepticus; Survival Analysis; Treatment Outcome | 1998 |
Outcome evaluation of gabapentin as add-on therapy for partial seizures. "NEON" Study Investigators Group. Neurontin Evaluation of Outcomes in Neurological Practice.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurologic Examination; Phenobarbital; Phenytoin; Primidone; Quality of Life; Valproic Acid | 1998 |
A comparison of four treatments for generalized convulsive status epilepticus. Veterans Affairs Status Epilepticus Cooperative Study Group.
Topics: Aged; Anticonvulsants; Diazepam; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Lorazepam; Male; Middle Aged; Phenobarbital; Phenytoin; Status Epilepticus; Treatment Outcome | 1998 |
[Treatment for generalized seizures: the best of four methods].
Topics: Anticonvulsants; Diazepam; Epilepsy; Humans; Lorazepam; Phenobarbital; Phenytoin | 1999 |
Anti-epileptic drug intake adherence. The value of the blood drug level measurement and the clinical approach.
Topics: Anticonvulsants; Carbamazepine; Cross-Sectional Studies; Drug Monitoring; Epilepsy; Female; Humans; Male; Patient Compliance; Phenobarbital; Phenytoin | 1998 |
Does withdrawal of different antiepileptic drugs have different effects on seizure recurrence? Further results from the MRC Antiepileptic Drug Withdrawal Study.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Combinations; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Proportional Hazards Models; Recurrence; Risk Assessment; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1999 |
A case control study and one year follow-up of registered epilepsy cases in a resettlement colony of North India, a developing tropical country.
Topics: Adolescent; Adult; Anticonvulsants; Case-Control Studies; Child; Craniocerebral Trauma; Developmental Disabilities; Epilepsy; Female; Fever; Follow-Up Studies; Humans; India; Male; Matched-Pair Analysis; Phenobarbital; Phenytoin; Risk Factors; Seizures | 1999 |
Phenobarbital compared with phenytoin for the treatment of neonatal seizures.
Topics: Anticonvulsants; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Seizures; Single-Blind Method; Treatment Failure | 1999 |
Age-related alteration of carbamazepine-serum protein binding in man.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anticonvulsants; Child; Child, Preschool; Diethylcarbamazine; Drug Therapy, Combination; Epilepsy; Humans; Linear Models; Lipoxygenase Inhibitors; Middle Aged; Neuralgia; Orosomucoid; Phenobarbital; Phenytoin; Serum Albumin | 1999 |
Effect of felbamate on clobazam and its metabolite kinetics in patients with epilepsy.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Epilepsies, Partial; Felbamate; Female; Humans; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Prospective Studies; Triazines; Valproic Acid | 1999 |
Electrographic seizures in neonates correlate with poor neurodevelopmental outcome.
Topics: Anticonvulsants; Asphyxia Neonatorum; Demography; Developmental Disabilities; Electroencephalography; Epilepsies, Partial; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Lorazepam; Male; Monitoring, Physiologic; Phenobarbital; Phenytoin; Prognosis; Survival Rate; Treatment Outcome | 2000 |
Epilepsy control with phenobarbital or phenytoin in rural south India: the Yelandur study.
Topics: Adult; Anticonvulsants; Epilepsy, Tonic-Clonic; Female; Humans; India; Logistic Models; Male; Patient Care Team; Phenobarbital; Phenytoin; Rural Population; Treatment Outcome | 2001 |
Add-on phenytoin fails to prevent early seizures after surgery for supratentorial brain tumors: a randomized controlled study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cerebellar Neoplasms; Craniotomy; Female; Humans; Incidence; Intraoperative Care; Male; Middle Aged; Phenobarbital; Phenytoin; Postoperative Care; Risk Factors; Seizures | 2002 |
[Evaluation of antiepileptic therapy during pregnancy].
Topics: Adult; Anticonvulsants; Apgar Score; Drug Therapy, Combination; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Primidone; Valproic Acid | 2002 |
Topiramate therapeutic monitoring in patients with epilepsy: effect of concomitant antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Phenobarbital; Phenytoin; Prospective Studies; Topiramate; Triazines; Valproic Acid | 2002 |
Pharmacokinetic interaction between albendazole sulfoxide enantiomers and antiepileptic drugs in patients with neurocysticercosis.
Topics: Adult; Albendazole; Anthelmintics; Anticonvulsants; Area Under Curve; Carbamazepine; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Interactions; Female; Humans; Isomerism; Male; Neurocysticercosis; Phenobarbital; Phenytoin | 2002 |
Microdialysis sampling of carbamazepine, phenytoin and phenobarbital in subcutaneous extracellular fluid and subdural cerebrospinal fluid in humans: an in vitro and in vivo study of adsorption to the sampling device.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Extracellular Space; Female; Humans; Male; Microdialysis; Middle Aged; Phenobarbital; Phenytoin; Protein Binding | 2002 |
Eight-year study of childhood status epilepticus: midazolam infusion in management and outcome.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Female; GABA Modulators; Humans; Infant; Infusions, Intravenous; Injections, Intravenous; Male; Midazolam; Phenobarbital; Phenytoin; Status Epilepticus; Treatment Outcome | 2002 |
Prophylactic anticonvulsants in patients with brain tumour.
Topics: Anticonvulsants; Brain Neoplasms; Disease Progression; Female; Humans; Incidence; Male; Middle Aged; Neoplasm Metastasis; Patient Compliance; Phenobarbital; Phenytoin; Prospective Studies; Risk Factors; Seizures; Sex Factors; Survival Rate; Treatment Failure | 2003 |
Uncoupling of EEG-clinical neonatal seizures after antiepileptic drug use.
Topics: Anticonvulsants; Electroencephalography; Evoked Potentials; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Phenobarbital; Phenytoin; Spasms, Infantile; Treatment Outcome | 2003 |
Phenytoin and phenobarbital stable isotope studies in neonates.
Topics: Anticonvulsants; Carbon Isotopes; Epilepsy; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infant, Newborn; Infant, Premature; Intensive Care Units; Nitrogen Isotopes; Phenobarbital; Phenytoin; Seizures; Time Factors | 2003 |
Interaction profile of Zizyphus jujuba with phenytoin, phenobarbitone, and carbamazepine in maximal electroshock-induced seizures in rats.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Chi-Square Distribution; Chromatography, High Pressure Liquid; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Fruit; Glutathione; Lipid Peroxidation; Male; Maze Learning; Phenobarbital; Phenytoin; Phytotherapy; Rats; Rats, Wistar; Seizures; Ziziphus | 2012 |
Phenobarbitone versus phenytoin for treatment of neonatal seizures: an open-label randomized controlled trial.
Topics: Anticonvulsants; Electroencephalography; Female; Humans; India; Infant, Newborn; Infant, Newborn, Diseases; Male; Phenobarbital; Phenytoin; Seizures | 2013 |
Quantification of the impact of enzyme-inducing antiepileptic drugs on irinotecan pharmacokinetics and SN-38 exposure.
Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Carbamazepine; Drug Interactions; Enzyme Induction; Female; Glioma; Glucuronates; Humans; Irinotecan; Male; Middle Aged; Phenobarbital; Phenytoin | 2015 |
Efficacy and safety of levetiracetam in the management of seizures in neonates.
Topics: Anticonvulsants; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Iran; Levetiracetam; Male; Phenobarbital; Phenytoin; Piracetam; Seizures; Treatment Outcome | 2016 |
Influence of Inflammation on the Pharmacokinetics of Perampanel.
Topics: Adolescent; Adult; Anticonvulsants; C-Reactive Protein; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Humans; Inflammation; Male; Middle Aged; Nitriles; Phenobarbital; Phenytoin; Pyridones; Time Factors; Young Adult | 2018 |
2076 other study(ies) available for phenytoin and phenobarbital
| Article | Year |
|---|---|
Synthesis and anticonvulsant activity of enaminones.
Topics: Amines; Animals; Anticonvulsants; Drug Evaluation, Preclinical; Electric Stimulation; Kindling, Neurologic; Male; Mice; Rats; Seizures; Structure-Activity Relationship | 1992 |
2-Phenyl-3H-imidazo[4,5-b]pyridine-3-acetamides as non-benzodiazepine anticonvulsants and anxiolytics.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Benzodiazepines; Binding, Competitive; Cerebral Cortex; gamma-Aminobutyric Acid; Imidazoles; Mice; Mice, Inbred ICR; Molecular Structure; Pyridines; Rats; Receptors, GABA-A; Seizures | 1991 |
Preparation and anticonvulsant activity of a series of functionalized alpha-heteroatom-substituted amino acids.
Topics: Acetamides; Amino Acids; Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Electroshock; Male; Mice; Molecular Structure; Nitrogen; Oxygen; Seizures; Structure-Activity Relationship; Sulfur | 1991 |
Synthesis and anticonvulsant activity of imidooxy derivatives.
Topics: Animals; Anticonvulsants; Chickens; Electroshock; Imides; Indicators and Reagents; Molecular Structure; Phthalimides; Reflex; Structure-Activity Relationship; Succinimides | 1991 |
Synthesis and anticonvulsant activity of 2-iminohydantoins.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Hydantoins; Male; Mice; Structure-Activity Relationship | 1991 |
2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Gerbillinae; Hippocampus; Hypoxia; Male; Mice; Neurons; Phencyclidine; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Triazoles | 1990 |
Preparation and anticonvulsant activity of a series of functionalized alpha-aromatic and alpha-heteroaromatic amino acids.
Topics: Amino Acids; Animals; Anticonvulsants; Male; Mice; Structure-Activity Relationship | 1990 |
Synthesis and anticonvulsant activity of 2-benzylglutarimides.
Topics: Animals; Anticonvulsants; Benzyl Compounds; Mice; Piperidines; Piperidones; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1990 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Metabolism of 3-(p-chlorophenyl)pyrrolidine. Structural effects in conversion of a prototype gamma-aminobutyric acid prodrug to lactam and gamma-aminobutyric acid type metabolites.
Topics: Amino Acids; Animals; Baclofen; Brain; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; gamma-Aminobutyric Acid; Isoniazid; Lactams; Liver; Male; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Molecular Structure; Monoamine Oxidase; Oxidation-Reduction; Prodrugs; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1989 |
Anticonvulsant activity of piperidinol and (dialkylamino)alkanol esters.
Topics: Amino Alcohols; Animals; Anticonvulsants; Ataxia; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Diazepam; Electroshock; Esters; Muscimol; Pentylenetetrazole; Phenytoin; Piperidines; Rats; Receptors, GABA-A; Structure-Activity Relationship | 1986 |
Triazolines. 14. 1,2,3-Triazolines and triazoles, a new class of anticonvulsants. Drug design and structure-activity relationships.
Topics: Animals; Anticonvulsants; Electroshock; Mice; Seizures; Structure-Activity Relationship; Triazoles | 1988 |
Substituted 1,3,4-thiadiazoles with anticonvulsant activity. 3. Guanidines.
Topics: Animals; Chemical Phenomena; Chemistry; Electroshock; Guanidines; Mice; Pentylenetetrazole; Rats; Seizures; Thiadiazoles | 1987 |
Anticonvulsant activity of 2- and 3-aminobenzanilides.
Topics: Anilides; Aniline Compounds; Animals; Anticonvulsants; Electroshock; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures | 1986 |
Substituted 1,3,4-thiadiazoles with anticonvulsant activity. 1. Hydrazines.
Topics: Animals; Anticonvulsants; Hydrazines; Male; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1986 |
Substituted 1,3,4-thiadiazoles with anticonvulsant activity. 2. Aminoalkyl derivatives.
Topics: Animals; Anticonvulsants; Mice; Rats; Structure-Activity Relationship; Thiadiazoles | 1986 |
Functionalized DL-amino acid derivatives. Potent new agents for the treatment of epilepsy.
Topics: Amino Acids; Animals; Anticonvulsants; Epilepsy; Magnetic Resonance Spectroscopy; Male; Mice; Seizures; Stereoisomerism; Structure-Activity Relationship | 1987 |
Synthesis and activity of 6-aryl-3-(hydroxypolymethyleneamino)pyridazines in animal models of epilepsy.
Topics: Animals; Anticonvulsants; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Female; Hypnotics and Sedatives; Kindling, Neurologic; Male; Mice; Motor Skills; Papio; Pentylenetetrazole; Photic Stimulation; Pyridazines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1986 |
Anticonvulsant activity of some 4-aminobenzanilides.
Topics: Anilides; Animals; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Electroshock; Male; Mice; Pentylenetetrazole; Seizures; Structure-Activity Relationship | 1985 |
Synthesis and central nervous system properties of 2-[(alkoxycarbonyl)amino]-4(5)-phenyl-2-imidazolines.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Body Temperature Regulation; Central Nervous System; Central Nervous System Agents; Imidazoles; Indicators and Reagents; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscle Relaxants, Central; Myocardium; Norepinephrine; Posture; Reserpine; Structure-Activity Relationship | 1984 |
Anticonvulsant activity of some 4-aminobenzamides.
Topics: Animals; Anticonvulsants; Benzamides; Bicuculline; Electroshock; Male; Mice; Pentylenetetrazole; Seizures | 1984 |
1-(Naphthylalkyl)-1H-imidazole derivatives, a new class of anticonvulsant agents.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Electroshock; Female; Imidazoles; Male; Mice; Naphthalenes; Rats; Structure-Activity Relationship | 1981 |
Synthesis and anticonvulsant activity of enaminones. 3. Investigations on 4'-, 3'-, and 2'-substituted and polysubstituted anilino compounds, sodium channel binding studies, and toxicity evaluations.
Topics: Animals; Anticonvulsants; Batrachotoxins; Kidney; Liver; Male; Mice; Rats; Rats, Inbred F344; Sodium Channels; Structure-Activity Relationship | 1995 |
Synthesis and anticonvulsant activities of alpha-acetamido-N-benzylacetamide derivatives containing an electron-deficient alpha-heteroaromatic substituent.
Topics: Acetamides; Animals; Anticonvulsants; Male; Mice; Structure-Activity Relationship | 1994 |
Synthesis and anticonvulsant properties of new benzylpyridazine derivatives.
Topics: Animals; Anticonvulsants; Lamotrigine; Male; Mice; Molecular Conformation; Pyridazines; Structure-Activity Relationship; Triazines | 1994 |
Synthesis and anticonvulsant activities of alpha-heterocyclic alpha-acetamido-N-benzylacetamide derivatives.
Topics: Acetamides; Animals; Anticonvulsants; Benzeneacetamides; Benzyl Compounds; Furans; Heterocyclic Compounds; Male; Mice; Mice, Inbred Strains; Seizures; Stereoisomerism; Structure-Activity Relationship | 1993 |
Synthesis and CLOGP correlation of imidooxy anticonvulsants.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Electroshock; Male; Mice; Models, Molecular; Molecular Structure; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Seizures; Spiro Compounds; Structure-Activity Relationship | 1993 |
Synthesis and anticonvulsant activities of N-Benzyl-2-acetamidopropionamide derivatives.
Topics: Acetamides; Animals; Anticonvulsants; Benzylamines; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1996 |
Synthesis and evaluation of N-(phenylacetyl)trifluoromethanesulfonamides as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Body Weight; Cytochrome P-450 Enzyme System; Epilepsy; Mesylates; Mice; NADPH-Ferrihemoprotein Reductase; Organ Size; Oxidoreductases, O-Demethylating; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides | 1996 |
Synthesis and anticonvulsant activity of 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives.
Topics: Animals; Anticonvulsants; Electric Stimulation; Injections, Intraperitoneal; Male; Mice; Oxazoles; Rats; Seizures; Thiazoles | 1998 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Synthesis and structural studies of aza analogues of functionalized amino acids: new anticonvulsant agents.
Topics: Animals; Anticonvulsants; Aza Compounds; Crystallography, X-Ray; Electroshock; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Rats; Seizures; Semicarbazides; Structure-Activity Relationship | 2001 |
Design and evaluation of affinity labels of functionalized amino acid anticonvulsants.
Topics: Affinity Labels; Amino Acids; Animals; Anticonvulsants; Electroshock; Isothiocyanates; Mice; Radioligand Assay; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship | 2002 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Synthesis and anticonvulsant activity of 7-alkoxyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolines.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Mice; Neurotoxicity Syndromes; Quinolines; Seizures; Structure-Activity Relationship | 2005 |
Discovery of N-(2,6-dimethylphenyl)-substituted semicarbazones as anticonvulsants: hybrid pharmacophore-based design.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Benzamides; Chemical and Drug Induced Liver Injury; Drug Design; Female; gamma-Aminobutyric Acid; Male; Mice; Models, Molecular; Motor Activity; Rats; Seizures; Semicarbazones; Structure-Activity Relationship | 2005 |
Synthesis and anticonvulsant activity of new N-1',N-3'-disubstituted-2'H,3H,5'H-spiro-(2-benzofuran-1,4'-imidazolidine)-2',3,5'-triones.
Topics: Animals; Anticonvulsants; Benzofurans; Imidazolidines; Mice; Molecular Structure; Pentylenetetrazole; Seizures; Structure-Activity Relationship | 2006 |
Synthesis and anticonvulsant activity of 4-(2-(2,6-dimethylphenylamino)-2-oxoethylamino)-N-(substituted)butanamides: a pharmacophoric hybrid approach.
Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Chemistry, Pharmaceutical; Drug Design; Ethanol; gamma-Aminobutyric Acid; Mice; Models, Chemical; Molecular Structure; Motor Activity; Neurons; Seizures; Structure-Activity Relationship | 2007 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Synthesis of some novel N4-(naphtha[1,2-d]thiazol-2-yl)semicarbazides as potential anticonvulsants.
Topics: Animals; Anticonvulsants; Brain Chemistry; Glutathione Peroxidase; Malondialdehyde; Mice; Motor Activity; Rats; Seizures; Semicarbazides; Structure-Activity Relationship; Superoxide Dismutase | 2009 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Synthesis and preliminary evaluation of some substituted coumarins as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Molecular Structure; Pentylenetetrazole; Seizures; Stereoisomerism; Structure-Activity Relationship; Strychnine | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Synthesis and anticonvulsant activities of N-benzyl (2R)-2-acetamido-3-oxysubstituted propionamide derivatives.
Topics: Acetamides; Animals; Anticonvulsants; Binding Sites; Lacosamide; Male; Mice; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Synthesis, anticonvulsant and CNS depressant activity of some new bioactive 1-(4-substituted-phenyl)-3-(4-oxo-2-phenyl/ethyl-4H-quinazolin-3-yl)-urea.
Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System Depressants; Male; Mice; Molecular Structure; Pentylenetetrazole; Quinazolinones; Rats; Rats, Sprague-Dawley; Rats, Wistar; Seizures; Structure-Activity Relationship; Urea | 2009 |
Lacosamide isothiocyanate-based agents: novel agents to target and identify lacosamide receptors.
Topics: Acetamides; Animals; Anticonvulsants; Brain; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Isothiocyanates; Lacosamide; Male; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Proteome; Seizures; Serine; Stereoisomerism; Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Synthesis and anticonvulsant activities of (R)-N-(4'-substituted)benzyl 2-acetamido-3-methoxypropionamides.
Topics: Acetamides; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Electroshock; Hippocampus; Kindling, Neurologic; Male; Mice; Molecular Structure; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Serine; Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Triazole incorporated thiazoles as a new class of anticonvulsants: design, synthesis and in vivo screening.
Topics: Animals; Anticonvulsants; Drug Design; Electroconvulsive Therapy; Lethal Dose 50; Mice; Triazoles | 2010 |
Synthesis, anticonvulsant and toxicity screening of newer pyrimidine semicarbazone derivatives.
Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Drug Synergism; Epilepsy; Liver; Mice; Nervous System; Pyrimidines; Semicarbazones | 2010 |
Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities.
Topics: Acetamides; Alanine; Amides; Amino Acids; Animals; Anticonvulsants; Benzylamines; Drug Evaluation, Preclinical; Lacosamide; Mice; Pain; Rats; Seizures; Structure-Activity Relationship; Treatment Outcome | 2010 |
The structure-activity relationship of the 3-oxy site in the anticonvulsant (R)-N-benzyl 2-acetamido-3-methoxypropionamide.
Topics: Acetamides; Animals; Anticonvulsants; Electroshock; Hydrophobic and Hydrophilic Interactions; Lacosamide; Male; Mice; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship | 2010 |
Synthesis and anticonvulsant activity of N-3-arylamide substituted 5,5-cyclopropanespirohydantoin derivatives.
Topics: Amides; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Hydantoins; Mice; Molecular Structure; Seizures; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Synthesis and anticonvulsant activity of 7-phenyl-6,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-ones and their derivatives.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bicuculline; Electroshock; Isoniazid; Mice; Pentylenetetrazole; Pyrimidinones; Seizures; Semicarbazides; Structure-Activity Relationship; Triazoles | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Primary amino acid derivatives: compounds with anticonvulsant and neuropathic pain protection activities.
Topics: Amino Acids; Analgesics; Animals; Anticonvulsants; Convulsants; Electroshock; Formaldehyde; Male; Mice; Neuralgia; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship | 2011 |
Primary amino acid derivatives: substitution of the 4'-N'-benzylamide site in (R)-N'-benzyl 2-amino-3-methylbutanamide, (R)-N'-benzyl 2-amino-3,3-dimethylbutanamide, and (R)-N'-benzyl 2-amino-3-methoxypropionamide provides potent anticonvulsants with pain
Topics: Amino Acids; Analgesics; Animals; Anticonvulsants; Butyrates; Male; Mice; Neuralgia; Pain Measurement; Propionates; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship | 2011 |
Defining the structural parameters that confer anticonvulsant activity by the site-by-site modification of (R)-N'-benzyl 2-amino-3-methylbutanamide.
Topics: Aminobutyrates; Animals; Anticonvulsants; Male; Mice; Rats; Rats, Sprague-Dawley; Seizures; Solubility; Stereoisomerism; Structure-Activity Relationship | 2011 |
Synthesis and anticonvulsant activity of novel 2,6-diketopiperazine derivatives. Part 1: perhydropyrrole[1,2-a]pyrazines.
Topics: Animals; Anticonvulsants; Diketopiperazines; Electroshock; Epilepsy; Humans; Male; Mice; Models, Molecular; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Rats, Wistar; Seizures; Sodium Channel Blockers; Sodium Channels | 2011 |
Design and synthesis of novel stiripentol analogues as potential anticonvulsants.
Topics: Animals; Anticonvulsants; Dioxolanes; Drug Design; Hand Strength; Male; Mice; Seizures; Stereoisomerism; Toxicity Tests | 2012 |
Synthesis and anticonvulsant activity of 1-(8-(benzyloxy)quinolin-2-yl)-6-substituted-4,6-diazaspiro[2,4]heptane-5,7-diones.
Topics: Animals; Anticonvulsants; Biological Assay; Electroshock; Heptanes; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Molecular Structure; Quinolines; Seizures; Spiro Compounds; Structure-Activity Relationship; Toxicity Tests | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Synthesis, anticonvulsant activity, and neuropathic pain-attenuating activity of N-benzyl 2-amino-2-(hetero)aromatic acetamides.
Topics: Acetamides; Amino Acids; Animals; Anticonvulsants; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Mice; Mice, Inbred Strains; Molecular Structure; Neuralgia; Seizures; Structure-Activity Relationship | 2012 |
Synthesis and anticonvulsant activity of ethyl 1-(2-arylhydrazinecarboxamido)-2,2-dimethylcyclopropanecarboxylate derivatives.
Topics: Animals; Anticonvulsants; Chemistry Techniques, Synthetic; Hydrazines; Male; Mice; Motor Activity; Rotarod Performance Test; Seizures | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
(Biphenyl-4-yl)methylammonium chlorides: potent anticonvulsants that modulate Na+ currents.
Topics: Ammonium Compounds; Animals; Anticonvulsants; Biphenyl Compounds; Male; Methylamines; Mice; Rats; Rats, Sprague-Dawley; Sodium Channels | 2013 |
Novel fluorinated pyrrolo[1,2-a]pyrazine-2,6-dione derivatives: synthesis and anticonvulsant evaluation in animal models of epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Halogenation; Hydrocarbons, Fluorinated; Male; Mice; Molecular Structure; Pentylenetetrazole; Pilocarpine; Pyrazines; Pyrroles; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship | 2014 |
Design, synthesis and pharmacological evaluation of N-[4-(4-(alkyl/aryl/heteroaryl)-piperazin-1-yl)-phenyl]-carbamic acid ethyl ester derivatives as novel anticonvulsant agents.
Topics: Animals; Anticonvulsants; Carbamates; Drug Design; Electroshock; Epilepsy; Mice; Pentylenetetrazole; Piperazine; Piperazines; Seizures | 2015 |
Chimeric derivatives of functionalized amino acids and α-aminoamides: compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels.
Topics: Acetamides; Administration, Oral; Amides; Amino Acids; Animals; Anticonvulsants; Cerebral Cortex; Electroshock; HEK293 Cells; Humans; Injections, Intraperitoneal; Male; Mice; Neurons; Patch-Clamp Techniques; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship; Voltage-Gated Sodium Channel Blockers; Voltage-Gated Sodium Channels | 2015 |
Synthesis of 2,6-dicarbethoxy-3,5-diaryltetrahydro-1,4-thiazine-1,1-dioxide derivatives as potent anticonvulsant agents.
Topics: Animals; Anticonvulsants; Crystallography, X-Ray; Cyclic S-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Injections, Intraperitoneal; Mice; Models, Molecular; Molecular Structure; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Thiazines | 2015 |
Estimation of the lipophilicity of purine-2,6-dione-based TRPA1 antagonists and PDE4/7 inhibitors with analgesic activity.
Topics: Analgesics; Benzeneacetamides; Cyclic Nucleotide Phosphodiesterases, Type 7; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Phenylbutyrates; Phosphodiesterase 4 Inhibitors; Principal Component Analysis; Quantitative Structure-Activity Relationship; TRPA1 Cation Channel; Xanthines | 2021 |
Interactions between anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Humans; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Thiazines | 1975 |
Prognosis and therapy of complex partial seizures with barbiturates, hydantoins, and other drugs.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Prognosis; Succinimides; Thiazines; Valproic Acid | 1975 |
Activity of gamma-glutamyl transpeptidase in serum of patients receiving anticonvulsant of anticoagulant therapy.
Topics: Alkaline Phosphatase; Anticoagulants; Anticonvulsants; Aspartate Aminotransferases; Epilepsy; gamma-Glutamyltransferase; Humans; Phenobarbital; Phenytoin; Prothrombin Time | 1976 |
Resistant transitory epilepsy in children.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Carbamazepine; Child, Preschool; Encephalomyelitis, Acute Disseminated; Epilepsy; Female; Follow-Up Studies; Humans; Male; Phenobarbital; Phenytoin; Smallpox Vaccine; Thiazines | 1976 |
The effect of microsomal enzyme inducing drugs on reproductive function in the ewe.
Topics: Animals; Corpus Luteum; Enzyme Induction; Estrus; Female; Liver; Luteinizing Hormone; Microsomes, Liver; Organ Size; Phenobarbital; Phenylbutazone; Phenytoin; Piperazines; Pregnancy; Pregnenolone; Progesterone; Reproduction; Sheep; Sleep | 1975 |
Vasopressin-stimulated movement of drugs and uric acid across the toad urinary bladder.
Topics: Adenine; Animals; Anti-Bacterial Agents; Anura; Butanols; Cell Membrane Permeability; Cyclic AMP; Cyclohexanones; Female; Fluorouracil; Glutethimide; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Phloretin; Stimulation, Chemical; Uric Acid; Urinary Bladder; Vasopressins | 1976 |
[Determination of phenobarbital, mephenytoin and diphenylhydantoin in the surveillance of anticonvulsant treatment].
Topics: Barbiturates; Child; Chromatography, Gas; Epilepsy; Ether; Humans; Hydantoins; Mephenytoin; Methylation; Phenobarbital; Phenytoin; Solvents; Temperature | 1976 |
Application of a vidicon spectrometer for simultaneous multicomponent drug determinations.
Topics: Acetaminophen; Aminophylline; Barbiturates; Computers; Humans; Pharmaceutical Preparations; Phenobarbital; Phenylbutazone; Phenytoin; Procainamide; Regression Analysis; Salicylamides; Secobarbital; Spectrophotometry, Ultraviolet; Time Factors | 1976 |
Salivary levels of anticonvulsants: a practical approach to drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Saliva | 1977 |
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; Ethionamide; Female; Humans; Hycanthone; Male; Metronidazole; Neoplasms; Neoplasms, Experimental; Oxazepam; Oxymetholone; Oxyphenbutazone; Oxyquinoline; Phenacetin; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Pyrimethamine; Risk | 1977 |
Simultaneous measurement of phenobarbital, phenytoin, primidone, ethosuximide, and carbamazepine in serum by high-pressure liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Hot Temperature; Humans; Hydrogen-Ion Concentration; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
A sensitive method for gas-chromatographic assay of barbiturates in body fluids.
Topics: Barbiturates; Chromatography, Gas; Humans; Phenobarbital; Phenytoin | 1977 |
Application of orthogonal functions to the spectrophotometric determination of phenytoin and phenobarbitone in pharmaceutical preparations.
Topics: Capsules; Drug Combinations; Methods; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet; Statistics as Topic | 1977 |
Measurement of anti-epileptic drugs in plasma by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Phenobarbital; Phenytoin; Primidone; Quality Control; Thiazines | 1977 |
[Inhibitory processes in the cerebral cortex and the anticonvulsive action of benzodiazepine derivatives].
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Brain; Cats; Cerebral Cortex; Clonazepam; Diazepam; Electrophysiology; gamma-Aminobutyric Acid; Lorazepam; Medazepam; Neural Inhibition; Phenobarbital; Phenytoin; Seizures; Semicarbazides | 1977 |
Further evidence for GABA-ergic mechanisms in the action of benzodiazepines.
Topics: Aminobutyrates; Animals; Anti-Anxiety Agents; Benzodiazepines; Bicuculline; Cats; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; Male; Mice; Phenobarbital; Phenytoin; Rabbits; Rats; Reflex; Sciatic Nerve; Thiosemicarbazones | 1977 |
The extraction of antiepileptic drugs. Model study on partition coefficients.
Topics: Anticonvulsants; Carbamazepine; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Solvents; Spectrum Analysis | 1978 |
Mass spectrometry of medicines. Quantitative determination by direct probe inlet system mass chromatography.
Topics: Aspirin; Barbital; Barbiturates; Caffeine; Mass Spectrometry; Pharmaceutical Preparations; Phenacetin; Phenobarbital; Phenytoin | 1978 |
Effect of liver microsome enzyme-inducing drugs on blood serum pentobarbital clearance and sleep time in sheep and rabbits.
Topics: Animals; Microsomes, Liver; Pentobarbital; Phenobarbital; Phenylbutazone; Phenytoin; Piperazines; Rabbits; Sheep; Sleep; Time Factors | 1978 |
Drug concentration in saliva.
Topics: Adolescent; Adult; Aged; Antipyrine; Chlorpropamide; Humans; Hydrogen-Ion Concentration; Male; Meperidine; Middle Aged; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Saliva; Tolbutamide | 1978 |
Excretion of antiepileptic drugs in sweat.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Phenobarbital; Phenytoin; Sweat; Temperature | 1978 |
An improved method for preparation of samples for the simultaneous assay of some antiepileptic drugs by gas-liquid chromatography.
Topics: Barbiturates; Body Fluids; Chromatography, Gas; Female; Humans; Milk, Human; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva | 1978 |
[Drug interactions in antiepileptic combination therapy].
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Thiazines; Time Factors; Urea; Valproic Acid | 1979 |
Use of anticonvulsant drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Catalytic tritiation of drugs and analysis of the tritium distribution by 3H n.m.r. spectroscopy.
Topics: Amphetamine; Catalysis; Dextropropoxyphene; Imipramine; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenobarbital; Phenytoin; Propranolol; Tritium | 1979 |
Gas-liquid chromatography of undervatized drugs after chromatographic extraction from blood.
Topics: Amobarbital; Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Chromatography, Gas; Gastric Juice; Glutethimide; Humans; Hypnotics and Sedatives; Methaqualone; Phenobarbital; Phenytoin; Piperidones; Primidone; Secobarbital | 1979 |
Amines, anticonvulsants, and epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Chromatography, Gas; Drug Therapy, Combination; Epilepsy; Fluorometry; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Middle Aged; Phenobarbital; Phenylacetates; Phenytoin; Primidone | 1975 |
Letter: Bioavailability of drugs after intramuscular injection.
Topics: Absorption; Administration, Oral; Adult; Biological Availability; Biotransformation; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Injections, Intramuscular; Male; Phenobarbital; Phenytoin; Primidone | 1975 |
Letter: Amines, anticonvulsants, and epilepsy.
Topics: Animals; Anticonvulsants; Brain; Epilepsy; Humans; Phenobarbital; Phenytoin; Rats; Serotonin | 1975 |
Editorial: Drug levels in epilepsy.
Topics: Adult; Biological Availability; Child; Dose-Response Relationship, Drug; Drug Tolerance; Epilepsy; Half-Life; Humans; Phenobarbital; Phenytoin; Prospective Studies | 1975 |
EEG changes after withdrawal of medication in epileptic patients.
Topics: Adult; Anticonvulsants; Brain; Electroencephalography; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome | 1975 |
Interactions of antiepileptic drugs.
Topics: Anti-Infective Agents; Anticonvulsants; Benzodiazepines; Biotransformation; Blood Proteins; Carbamazepine; Dextropropoxyphene; Dicumarol; Disulfiram; Drug Interactions; Ethosuximide; Humans; Intestinal Absorption; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Protein Binding; Thiazines | 1975 |
The effect of phenytoin and ethosuximide on primidone metabolism in patients with epilepsy.
Topics: Drug Interactions; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
Inhibition of the effects of alfathesin and other steroid anesthetics by catatoxic steroids in rats.
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Female; Ketosteroids; Phenobarbital; Phenytoin; Prednisolone; Pregnanediones; Pregnanes; Pregnenes; Pregnenolone Carbonitrile; Rats; Spironolactone; Steroids; Thyroxine; Time Factors | 1975 |
Letter: Pyridoxine and serum concentration of phenytoin and phenobarbitone.
Topics: Child; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pyridoxine; Time Factors | 1976 |
Anticonvulsants and parental epilepsy in the development of birth defects.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Epilepsy; Female; Finland; Follow-Up Studies; Humans; Intelligence Tests; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Retrospective Studies; United States | 1976 |
Letter: Anticonvulsants and fetal malformations.
Topics: Abnormalities, Drug-Induced; Epilepsy; Female; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1976 |
Measurement of diphenylhydantoin and phenobarbital by enzyme immunoassay and gas-liquid chromatography.
Topics: Chromatography, Gas; Glucosephosphate Dehydrogenase; Humans; Immunoassay; Phenobarbital; Phenytoin | 1976 |
Motor and electrical signs of epileptiform activity induced by penicillin in the spinal cords of decapitate cats.
Topics: Animals; Blood Pressure; Cats; Chloralose; Decerebrate State; Dose-Response Relationship, Drug; Penicillin G; Penicillinase; Peripheral Nerves; Phenobarbital; Phenytoin; Seizures; Spinal Cord; Spinal Nerve Roots | 1976 |
How doctors deal with epilepsy.
Topics: Adolescent; Adult; Aged; Automobile Driving; Diazepam; Drug Therapy, Combination; Electroencephalography; Epilepsy; Evaluation Studies as Topic; Follow-Up Studies; Humans; London; Middle Aged; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Referral and Consultation | 1977 |
The binding of phenobarbitone and phenytoin to kwashiorkor serum.
Topics: Alpha-Globulins; Blood Proteins; Child; Drug Interactions; Humans; In Vitro Techniques; Kwashiorkor; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin | 1977 |
Therapeutic and pharmacokinetic effects of increasing phenytoin in chronic epileptics on multiple drug therapy.
Topics: Adult; Biological Availability; Chronic Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1976 |
In vivo interaction of anticonvulsant drugs. The mathematical correlation of plasma levels of anticonvulsant drugs in epileptic patients.
Topics: Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone | 1978 |
Study of the stereoselectivity of the para-hydroxylation of diphenylhydantoin by the rat liver microsomal cytochrome P-450-dependent enzymes [proceedings].
Topics: Animals; Cytochrome P-450 Enzyme System; Kinetics; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Rats; Substrate Specificity | 1978 |
The medical treatment of epilepsy: antiepileptic drug interactions and teratogenicity.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Calcium; Carbamazepine; Child; Dicumarol; Digitoxin; Drug Interactions; Female; Humans; Male; Oxacillin; Phenobarbital; Phenytoin; Pregnancy; Vitamin D | 1979 |
Anticonvulsant drugs and cancer. A cohort study in patients with severe epilepsy.
Topics: Adolescent; Adult; Brain Neoplasms; Child; England; Epilepsy; Female; Follow-Up Studies; Humans; Male; Neoplasms; Phenobarbital; Phenytoin; Primidone; Risk; Sex Ratio; Spinal Cord Neoplasms; Time Factors; Wales | 1979 |
Gamma hydroxybutyrate in the monkey. II. Effect of chronic oral anticonvulsant drugs.
Topics: Administration, Oral; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Ethosuximide; Haplorhini; Hydroxybutyrates; Levodopa; Macaca mulatta; Phenobarbital; Phenytoin | 1978 |
[Blood level of antiepileptic drugs and therapeutic effect in mono- and polytherapy (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1978 |
Effect of carbamazepine, phenytoin and phenobarbitone on serum levels of thyroid hormones and thyrotropin in humans.
Topics: Adult; Carbamazepine; Epilepsy; Humans; Phenobarbital; Phenytoin; Radioimmunoassay; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine; Triiodothyronine, Reverse | 1978 |
Rapid metabolism of phenytoin: a method of calculating proper dosage.
Topics: Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Phenytoin | 1979 |
Pharmacological interactions of mesuximide with phenobarbital and phenytoin in hospitalized epileptic patients.
Topics: Adolescent; Adult; Child; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy, Absence; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Succinimides | 1979 |
Nicotine self-administration in rats.
Topics: Amphetamine; Animals; Caffeine; Chlordiazepoxide; Chlorpromazine; Drug Interactions; Drug Tolerance; Ethanol; Humans; Male; Mecamylamine; Nicotine; Pentolinium Tartrate; Phenobarbital; Phenytoin; Rats; Reinforcement, Psychology; Self Administration; Substance-Related Disorders | 1979 |
[The short periodicity of paroxysmal complex waves in electroencephalographic and clinical course of Creutzfeldt-Jakob disease (author's transl)].
Topics: Brain; Clonazepam; Creutzfeldt-Jakob Syndrome; Electroencephalography; Humans; Male; Middle Aged; Periodicity; Phenobarbital; Phenytoin; Sleep; Wakefulness | 1979 |
Relationships between plasma concentrations of diphenylhydantoin, phenobarbital, carbamazepine, and 3-sulfamoylmethyl-1,2-benzisoxazole (AD-810), a new anticonvulsant agent, and their anticonvulsant or neurotoxic effects in experimental animals.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Dogs; Dose-Response Relationship, Drug; Haplorhini; Isoxazoles; Male; Mice; Motor Skills; Oxazoles; Phenobarbital; Phenytoin; Rabbits; Rats; Seizures; Species Specificity | 1979 |
Successful treatment of atypical migraine of childhood with anticonvulsants.
Topics: Adolescent; Child; Child, Preschool; Electroencephalography; Female; Humans; Male; Migraine Disorders; Phenobarbital; Phenytoin | 1979 |
Bone morphology in epileptics.
Topics: Adult; Aged; Bone and Bones; Bone Diseases; Bone Resorption; Epilepsy; Female; Humans; Male; Middle Aged; Osteoclasts; Osteomalacia; Osteoporosis; Phenobarbital; Phenytoin | 1979 |
Bone mineral content in epileptics.
Topics: Aged; Bone and Bones; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Minerals; Muscle Contraction; Muscle Tonus; Osteomalacia; Phenobarbital; Phenytoin | 1979 |
Phenytoin serum levels in children with epilepsy: a micro immuno-assay technique.
Topics: Adolescent; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Male; Phenobarbital; Phenytoin | 1979 |
[Pharmacological influence of valproate on phenobarbitone and phenytoin serum concentrations in epileptic patients (author's transl)].
Topics: Drug Interactions; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1979 |
Letter: Exfoliative dermatitis during treatment with pheneturide.
Topics: Adult; Anticonvulsants; Dermatitis, Exfoliative; Epilepsy; Humans; Male; Phenobarbital; Phenylbutyrates; Phenytoin; Prednisolone; Urea | 1975 |
Mechaism of neuromuscular blockade with some antiepileptic drugs.
Topics: Abdominal Muscles; Anesthetics, Local; Animals; Anticonvulsants; Cats; Diaphragm; Ethosuximide; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscles; Neuromuscular Blocking Agents; Neuromuscular Junction; Neuromuscular Nondepolarizing Agents; Phenobarbital; Phenytoin; Rabbits; Rats; Trimethadione | 1976 |
The medical treatment of epilepsy: managing side effects of antiepileptic drugs.
Topics: Anticonvulsants; Blood; Cerebellar Ataxia; Child; Child, Preschool; Dextroamphetamine; Drug Eruptions; Gingival Hyperplasia; Humans; Hyperkinesis; Kidney; Liver; Phenobarbital; Phenytoin; Sleep Stages | 1979 |
Competitive nephelometric immunoassay method for antiepileptic drugs in patient blood.
Topics: Animals; Anticonvulsants; Binding, Competitive; Chemical Precipitation; Chromatography, Liquid; Colorimetry; Humans; Immunoassay; Lasers; Phenobarbital; Phenytoin; Rabbits | 1979 |
Seizure activity and anticonvulsant drug concentration.
Topics: Anticonvulsants; Child; Circadian Rhythm; Diazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroencephalography; Epilepsy; Female; Half-Life; Humans; Male; Phenobarbital; Phenytoin; Primidone; Sleep Stages; Sleep, REM; Telemetry | 1975 |
[Acute polyneuropathy caused by diphenylhydantoin intoxication (author's transl)].
Topics: Acute Disease; Adult; Cerebellar Diseases; Epilepsy, Tonic-Clonic; Humans; Male; Peripheral Nervous System Diseases; Phenobarbital; Phenytoin; Polyneuropathies | 1975 |
Calcium balance in drug-induced osteomalacia: response to vitamin D.
Topics: Adolescent; Adult; Anticonvulsants; Calcium; Cholecalciferol; Diet; Feces; Female; Humans; Male; Osteomalacia; Phenobarbital; Phenytoin | 1976 |
Calcium and folic acid absorption in patients taking anticonvulsant drugs.
Topics: Adult; Aged; Calcium; Cholecalciferol; Epilepsy; Folic Acid; Humans; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Rickets; Time Factors | 1975 |
[4 cases of osteomalacia during anticonvulsant or sedative treatment].
Topics: Adult; Aged; Anticonvulsants; Calcium; Cholecalciferol; Female; Humans; Hydroxycholecalciferols; Hyperparathyroidism, Secondary; Hypnotics and Sedatives; Male; Middle Aged; Osteomalacia; Parathyroid Hormone; Phenobarbital; Phenytoin | 1975 |
Effect of convulsions and anticonvulsive drugs on cerebrospinal fluid cyclic AMP in rabbits.
Topics: Animals; Aspartate Aminotransferases; Carbamazepine; Cyclic AMP; Depression, Chemical; Female; Male; Phenobarbital; Phenytoin; Rabbits; Seizures | 1976 |
Prophylactic effects of phenytoin, phenobarbital, and carbamazepine examined in kindling cat preparations.
Topics: Animals; Carbamazepine; Cats; Disease Models, Animal; Drug Evaluation, Preclinical; Electric Stimulation; Epilepsy; Male; Phenobarbital; Phenytoin; Seizures; Synaptic Transmission | 1976 |
Hodgkin's disease and granulomatous angiitis of the central nervous system.
Topics: Adult; Brain Diseases; Cerebral Cortex; Chickenpox; Dexamethasone; Herpesvirus 3, Human; Hodgkin Disease; Humans; Male; Nitrogen Mustard Compounds; Phenobarbital; Phenytoin; Prednisone; Procarbazine; Vascular Diseases; Vincristine | 1976 |
Inhibition of vitamin D-stimulated active transport of calcium of rat intestine by diphenylhydantoin-phenobarbital treatment.
Topics: Animals; Biological Transport, Active; Calcium; Cholecalciferol; Diffusion; Duodenum; Ergocalciferols; Hydroxycholecalciferols; Ileum; Intestine, Small; Male; Phenobarbital; Phenytoin; Phosphates; Rats; Vitamin D | 1976 |
Effects of gaba, gabob and some anticonvulsant drugs on dibutyryl cyclic AMP evoked seizures.
Topics: Aminobutyrates; Animals; Anticonvulsants; Bucladesine; Chickens; Diazepam; Electroencephalography; Female; gamma-Aminobutyric Acid; Phenobarbital; Phenytoin; Seizures | 1977 |
Cyclic AMP accumulation in cerebral cortical slices: effect of carbamazepine, phenobarbital, and phenytoin.
Topics: Adenosine; Animals; Brain Chemistry; Carbamazepine; Cyclic AMP; Female; In Vitro Techniques; Norepinephrine; Ouabain; Phenobarbital; Phenytoin; Rats | 1977 |
[Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, Preschool; Clonazepam; Diazepam; Electroencephalography; Epilepsy; Female; Humans; Infant; Male; Nitrazepam; Phenobarbital; Phenytoin; Primidone; Seizures; Spasms, Infantile; Syndrome | 1977 |
Inhibition of rat liver calciferol 25-hydroxylase activity with anticonvulsant drugs.
Topics: Animals; Cholecalciferol; Kinetics; Liver; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Steroid Hydroxylases | 1977 |
Cyclic nucleotides in epileptic brain: effects of pentylenetetrazol on regional cyclic AMP and cyclic GMP levels in vivo.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Cyclic GMP; Ethosuximide; Female; Hippocampus; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Thalamus | 1977 |
Effects of phenobarbital and diphenylhydantoin on acute vitamin D3 toxicity in the rat.
Topics: Animals; Body Weight; Cholecalciferol; Lethal Dose 50; Liver; Male; Phenobarbital; Phenytoin; Rats | 1978 |
Effect of diphenylhydantoin on the apposition of dentin. An experimental study in the rat.
Topics: Alkaline Phosphatase; Animals; Body Weight; Calcium; Cholecalciferol; Connective Tissue; Dentinogenesis; Female; Isoniazid; Liver; Male; Microsomes, Liver; Odontogenesis; Organ Size; Phenobarbital; Phenytoin; Phosphates; Rats; Sex Factors | 1977 |
Interaction of diphenylhydantoin (phenytoin) and phenobarbital with hormonal mediation of fetal rat bone resorption in vitro.
Topics: Animals; Bone and Bones; Bone Resorption; Calcitonin; Calcium; Cyclic AMP; Dihydroxycholecalciferols; Drug Synergism; Hormones; In Vitro Techniques; Parathyroid Hormone; Phenobarbital; Phenytoin; Rats | 1978 |
Hepatic drug metabolism after phenobarbital and diphenylhydantoin administration in the rat--influence of vitamin D3 status.
Topics: Animals; Calcium; Cholecalciferol; Hexobarbital; Liver; Male; Mixed Function Oxygenases; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Phosphorus; Rats; Sleep; Time Factors; Vitamin D Deficiency | 1979 |
Interactions of antiepileptic drugs on adenylate cyclase and phosphodiesterases in rat and mouse cerebrum.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Clonazepam; Cyclic AMP; Diazepam; Dopamine; Male; Norepinephrine; Phenobarbital; Phenytoin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats | 1979 |
Anticonvulsant drug actions on in vitro and in vivo levels of cyclic AMP in the mouse brain.
Topics: Adenosine; Animals; Anticonvulsants; Brain; Carbamazepine; Cerebellum; Cerebral Cortex; Clonazepam; Culture Techniques; Cyclic AMP; Diazepam; Male; Mice; Norepinephrine; Ouabain; Pentylenetetrazole; Phenobarbital; Phenytoin; Potassium; Premedication; Seizures | 1979 |
[Neurologic complications following medical treatment of epileptic patients].
Topics: Adolescent; Adult; Anticonvulsants; Ataxia; Benzodiazepines; Consciousness Disorders; Dysarthria; Eye Movements; Female; Handwriting; Humans; Hypotension; Male; Movement Disorders; Nervous System Diseases; Nystagmus, Pathologic; Peripheral Nervous System Diseases; Phenobarbital; Phenytoin; Sleep Wake Disorders; Tremor | 1979 |
[Clinical and experimental studies on the enzymes of liver, small intestinal mucosa and pancreas after chronic ethanol ingestion and anti-epileptic drugs (author's transl)].
Topics: Alcoholism; Animals; Glucaric Acid; Humans; Intestinal Mucosa; Intestine, Small; Liver; Male; NADPH-Ferrihemoprotein Reductase; Pancreas; Phenobarbital; Phenytoin; Rats; Succinate Cytochrome c Oxidoreductase | 1979 |
Organic nitrogen-selective detector used in gas-chromatographic determination of some anticonvulsant and barbiturate drugs in plasma and tissues.
Topics: Animals; Anticonvulsants; Barbiturates; Brain Chemistry; Carbamazepine; Chromatography, Gas; Horses; Humans; Hydantoins; Methods; Nitrogen; Phenobarbital; Phenytoin; Primidone; Time Factors | 1975 |
Theophylline-induced seizures in adults. Correlation with serum concentrations.
Topics: Adult; Aged; Creatinine; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Hydrogen-Ion Concentration; Injections, Intravenous; Kidney; Liver; Male; Middle Aged; Nitrogen; Phenobarbital; Phenytoin; Seizures; Theophylline; Urea | 1975 |
A primate model for testing anticonvulsant drugs.
Topics: Allyl Compounds; Animals; Anticonvulsants; Carbamazepine; Chromatography, Gas; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Evaluation, Preclinical; Electroencephalography; Ethosuximide; Female; Glycine; Male; Myoclonus; Papio; Phenobarbital; Phenytoin; Photic Stimulation; Primidone; Seizures; Thiazines | 1975 |
Plasma albumin concentration and diphenylhydantoin binding in man.
Topics: Adolescent; Adult; Aged; Aspirin; Blood Protein Electrophoresis; Blood-Brain Barrier; Chromatography, Gas; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Hyperbilirubinemia; Male; Middle Aged; Penicillin G; Phenobarbital; Phenytoin; Protein Binding; Radioligand Assay; Serum Albumin; Ultrafiltration; Uremia | 1975 |
Involuntary movements caused by phenytoin intoxication in epileptic patients.
Topics: Adult; Chlorpheniramine; Diazepam; Drug Interactions; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Movement Disorders; Phenobarbital; Phenytoin; Primidone; Thiazines | 1975 |
[Effects of combination of anti-epileptic drugs].
Topics: Adrenergic beta-Antagonists; Anticonvulsants; Benzodiazepines; Carbamazepine; Digitoxin; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Lithium; Phenobarbital; Phenytoin; Primidone; Thiazines; Tolbutamide; Tranquilizing Agents | 1975 |
The effect of the anticonvulsants phenobarbital and diphenylhydantoin on intestinal absorption of calcium.
Topics: Animals; Calcium; Intestinal Absorption; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1979 |
The effect of various drugs on maternal serum cystine aminopeptidase.
Topics: Adolescent; Adult; Aminopeptidases; Cystinyl Aminopeptidase; Diazepam; Female; Humans; In Vitro Techniques; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1977 |
Changes in seizure susceptibility after intracerebral treatment with 5,7-dihydroxytryptamine: role of serotonergic neurons.
Topics: 5,7-Dihydroxytryptamine; Acetazolamide; Animals; Anticonvulsants; Dihydroxytryptamines; Electroshock; Male; Neurons; Pentylenetetrazole; Phenobarbital; Phenytoin; Raphe Nuclei; Rats; Seizures; Serotonin | 1978 |
Effects of diphenylhydantoin and phenobarbital on voltage-clamped myelinated nerve.
Topics: Action Potentials; Animals; Anura; Calcium; Dose-Response Relationship, Drug; In Vitro Techniques; Nerve Fibers, Myelinated; Neural Conduction; Phenobarbital; Phenytoin; Potassium; Rana pipiens; Sodium | 1977 |
[Calcium metabolism and anticonvulsants drugs. Experimental study].
Topics: Alkaline Phosphatase; Animals; Body Weight; Calcium; Hydroxyproline; Liver; Male; Phenobarbital; Phenytoin; Phosphorus; Rats | 1979 |
Automated computer analysis for enzyme-multiplied immunological techniques.
Topics: Computers; Dose-Response Relationship, Immunologic; Evaluation Studies as Topic; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1977 |
Anticonvulsants in serum, determined with a fully mechanized enzyme analyzer.
Topics: Evaluation Studies as Topic; Glucosephosphate Dehydrogenase; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1977 |
Use of saliva in therapeutic drug monitoring.
Topics: Antipyrine; Caffeine; Ethosuximide; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Saliva; Theophylline | 1977 |
Phenobarbitol and phenytoin determined by enzyme immunoassay with a centrifugal analyzer.
Topics: Centrifugation; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1977 |
Phenytoin and phenobarbital assay by use of EMIT and the ABA-100.
Topics: Autoanalysis; Humans; Immunoenzyme Techniques; Methods; Phenobarbital; Phenytoin | 1977 |
Drug interactions during anticonvulsant therapy in childhood: diphenylhydantoin, primidone, phenobarbitone, clonazepam, nitrazepam, carbamazepin and dipropylacetate.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Nitrazepam; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1977 |
Management of childhood epilepsy.
Topics: Child; Epilepsy; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1977 |
Implications of measuring anticonvulsant blood levels in epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Epilepsy; Humans; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Valproic Acid | 1977 |
Enzyme immunoassay of phenytoin and phenobarbital with the centrifugal analyzer.
Topics: Centrifugation; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1977 |
Enzyme immunoassays with the miniature centrifugal fast analyzer.
Topics: Centrifugation; Glucosephosphate Dehydrogenase; Humans; Immunoenzyme Techniques; Methods; Phenobarbital; Phenytoin | 1977 |
Enzyme immunoassay of phenobarbital phenytoin, and primidone with the ABA-100 bichromatic analyzer.
Topics: Autoanalysis; Humans; Immunoenzyme Techniques; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Preliminary observations on valproic acid kinetics in patients with epilepsy.
Topics: Adult; Child; Chromatography, Gas; Epilepsy; Humans; Phenobarbital; Phenytoin; Valerates; Valproic Acid | 1977 |
Changes in sensitivity of mice to anticonvulsant drugs following bilateral olfactory bulb ablations.
Topics: Acetazolamide; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Nitrazepam; Olfactory Bulb; Phenobarbital; Phenylacetates; Phenytoin; Trimethadione; Urea; Valproic Acid | 1977 |
Determination of phenobarbital and phenytoin in serum by a mechanized enzyme immunoassay (EMIT) in comparison with a gas-liquid chromatographic method.
Topics: Child; Chromatography, Gas; Chromatography, Liquid; Female; Humans; Immunoenzyme Techniques; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Epilepsy and IgA deficiency--the effect of sodium valproate.
Topics: Adult; Agammaglobulinemia; Carbamazepine; Epilepsy; Female; Humans; Immunoglobulin A; Male; Phenobarbital; Phenytoin; Valerates; Valproic Acid | 1977 |
Choice of drug therapy in epilepsy.
Topics: Acetazolamide; Anticonvulsants; Benzodiazepines; Carbamazepine; Clonazepam; Epilepsy; Ethosuximide; Humans; Nitrazepam; Phenobarbital; Phenytoin; Valproic Acid | 1977 |
[Plasma levels of anticonvulsants. Experiences with routine plasma level determination of 6 different anticonvulsants].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
Enzyme immunoassay, with use of a centrifugal analyzer, of phenytoin, phenobarbital, and theophylline.
Topics: Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Theophylline | 1978 |
Effect of anticonvulsants on thalamic afterdischarge in rats and cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Diazepam; Electrocardiography; Electroencephalography; Female; Male; Phenobarbital; Phenytoin; Rats; Thalamus; Trimethadione; Valproic Acid | 1977 |
Antiepileptic drug development: I. History and a program for progress.
Topics: Anticonvulsants; Bromides; Drug Compounding; Drug Evaluation; Drug Evaluation, Preclinical; Drug Industry; History, 19th Century; History, 20th Century; Kinetics; National Institutes of Health (U.S.); Phenobarbital; Phenytoin; Research Support as Topic; Structure-Activity Relationship; United States | 1978 |
Long-term use of the major anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Time Factors; Valproic Acid | 1978 |
A micromethod for simultaneous estimation of blood levels of some commonly used antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Diazepam; Humans; Microchemistry; Nordazepam; Phenobarbital; Phenytoin | 1978 |
[The studies on the antiepileptic drug estimation by means of EMIT-AED (author's transl)].
Topics: Enzyme-Linked Immunosorbent Assay; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Reagent Kits, Diagnostic | 1978 |
Consecutive gas chromatographic determination of phenytoin, phenobarbital, primidone, phenylethylmalondiamide, carbamazepine, trimethadione, dimethadione, ethosuximide, and valproate from the same serum specimen.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Dimethadione; Ethosuximide; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Trimethadione; Valproic Acid | 1978 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Status Epilepticus; Valproic Acid | 1979 |
Study of the EMIT method for determination of anti-epileptic drugs in serum using an LKB 2086 reaction rate analyzer.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, Thin Layer; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1978 |
Effect of anticonvulsants on spiking activity induced by cortical freezing in cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Arousal; Carbamazepine; Cats; Diazepam; Electrocardiography; Electroencephalography; Female; Freezing; Gallamine Triethiodide; Immobilization; Male; Phenobarbital; Phenytoin; Taurine; Trimethadione; Valproic Acid; Visual Cortex | 1979 |
Valproic acid binding to human serum albumin and determination of free fraction in the presence of anticonvulsants and free fatty acids.
Topics: Anticonvulsants; Carbamazepine; Fatty Acids, Nonesterified; Humans; Linoleic Acids; Oleic Acids; Palmitic Acids; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Stearic Acids; Valproic Acid | 1979 |
Recent advances in drug therapy for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Drug Interactions; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Evaluation of automated enzyme immunoassays for five anticonvulsants and theophylline adapted to a centrifugal analyzer.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1979 |
The use of antiepileptic drugs.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Comparative trial of valproate sodium and clonazepam in chronic epilepsy.
Topics: Adult; Ataxia; Benzodiazepinones; Chronic Disease; Clonazepam; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sleep Stages; Sleep Wake Disorders; Valproic Acid | 1979 |
Anticonvulsant therapy in childhood. Recent advances.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1979 |
[The serum concentration of anticonvulsants -- pharmacokinetic findings and practical therapeutic applications (author's transl)].
Topics: Antacids; Anticonvulsants; Biological Availability; Carbamazepine; Chromatography, Gas; Clonazepam; Dosage Forms; Ethosuximide; Half-Life; Humans; Immunoenzyme Techniques; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone; Seizures; Valproic Acid | 1979 |
Homogeneous enzymoimmunoassay for anticonvulsant drugs: effects of hapten-enzyme bridge length.
Topics: Anticonvulsants; Glucosephosphate Dehydrogenase; Haptens; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Structure-Activity Relationship | 1979 |
Accuracy of serum anticonvulsant measurements. A comparison of enzyme multiplied immunoassay technique and gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1979 |
High pressure liquid chromatography for simultaneous analysis of anticonvulsants: comparison with EMIT system.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Immunoenzyme Techniques; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Reference Standards | 1979 |
Postictal pulmonary edema.
Topics: Adult; Epilepsy, Tonic-Clonic; Female; Humans; Penicillin G Procaine; Phenobarbital; Phenytoin; Pulmonary Edema; Radiography | 1977 |
Distribution of anticonvulsant drugs in gray and white matter of human brain.
Topics: Anticonvulsants; Brain; Carbamazepine; Epilepsies, Partial; Humans; Mesencephalon; Nervous System; Phenobarbital; Phenytoin; Spinal Cord | 1977 |
Effect of anticonvulsants on cortical focal seizure in cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Diazepam; Electrocardiography; Epilepsies, Partial; Female; Heart; Male; Phenobarbital; Phenytoin; Seizures; Trimethadione; Valproic Acid | 1977 |
[Anticonvulsants and simultaneous medication - a problem in pregnancy (author's transl)].
Topics: Adult; Anticonvulsants; Antiemetics; Dihydroergotamine; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Hypotension; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Complications, Cardiovascular; Self Administration; Self Medication; Vomiting | 1977 |
[Increase of the teratogenic power of diphenylhydantoin by phenobarbital in mice].
Topics: Animals; Drug Synergism; Female; Fetus; Mice; Phenobarbital; Phenytoin; Pregnancy; Teratogens | 1977 |
Mental dullness associated with left frontal continuous focal discharge.
Topics: Adult; Carbamazepine; Cognition Disorders; Electroencephalography; Epilepsy, Post-Traumatic; Frontal Lobe; Humans; Male; Phenobarbital; Phenytoin; Syndrome | 1977 |
[Diphenylhydantoin as an inducer for mutation test (author's transl)].
Topics: Animals; Male; Methylcholanthrene; Microsomes, Liver; Mutagens; Mutation; Phenobarbital; Phenytoin; Polychlorinated Biphenyls; Rats | 1977 |
Medical treatment of epilepsy: part I.
Topics: Anticonvulsants; Bromides; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Absence; Female; Humans; Infant; Phenobarbital; Phenytoin; Recurrence | 1978 |
Medical treatment of epilepsy: Part II.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Calcium; Child; Drug Interactions; Epilepsy; Epilepsy, Tonic-Clonic; Female; Gingival Hyperplasia; Humans; Hyperkinesis; Phenobarbital; Phenytoin; Pregnancy; Primidone; Status Epilepticus | 1978 |
Anticonvulsant therapy. Approaches to some common clinical problems.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Pregnancy; Seizures; Seizures, Febrile | 1979 |
Epilepsy among parents of children with facial clefts.
Topics: Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Humans; Male; Parents; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone | 1979 |
[Significance of pharmacogenic liver reactions for metabolism of endogenous and exogenous substances].
Topics: Carbamazepine; Diazepam; Drug-Related Side Effects and Adverse Reactions; Female; Fenoterol; Humans; Liver; Phenobarbital; Phenytoin; Pregnancy; Primidone | 1979 |
Hemodialysis and pregnancy.
Topics: Acute Kidney Injury; Adolescent; Adult; Chloral Hydrate; Female; Glutethimide; Humans; Infant, Newborn; Kidney Failure, Chronic; Peritoneal Dialysis; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Renal Dialysis | 1979 |
Is enflurane defluorination inducible in man?
Topics: Anesthetics; Blood Urea Nitrogen; Creatinine; Electrolytes; Enflurane; Ethanol; Female; Fluorides; Humans; Male; Methyl Ethers; Middle Aged; Phenobarbital; Phenytoin; Time Factors | 1979 |
Serum anticonvulsant monitoring by liquid chromatography with a methanolic mobile phase.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1979 |
Biochemical variables related to calcium metabolism in epileptics.
Topics: Aged; Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Phosphates; Primidone | 1979 |
Mucocutaneous eruptions due to antiepileptic drug therapy in children.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Erythema Multiforme; Female; Humans; Male; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Stevens-Johnson Syndrome | 1979 |
Intravenous phenytoin and phenobarbital: anticonvulsant action, brain content, and plasma binding in rat.
Topics: Animals; Brain; Infusions, Parenteral; Male; Phenobarbital; Phenytoin; Protein Binding; Rats | 1979 |
Serum phenytoin, phenobarbital, carbamazepine, albumin; and plasma estradiol, progesterone concentrations during the menstrual cycle in women with epilepsy.
Topics: Adult; Carbamazepine; Epilepsy; Estradiol; Female; Humans; Menstruation; Phenobarbital; Phenytoin; Progesterone; Serum Albumin | 1979 |
Improved determination of phenobarbital, primidone, and phenytoin by use of a preparative instrument for extraction, followed by gas chromatography.
Topics: Autoanalysis; Chromatography, Gas; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin; Primidone | 1979 |
[Drug therapy of epilepsy with control of the serum level of anti-epileptic agents].
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1979 |
Effect of phenytoin (DPH) treatment on methoxyflurane metabolism in rats.
Topics: Anesthetics; Animals; Drug Interactions; Enflurane; Ethers; Fluorides; Hydrocarbons, Fluorinated; In Vitro Techniques; Isoflurane; Kidney; Kinetics; Liver; Male; Methoxyflurane; Microsomes, Liver; Phenobarbital; Phenytoin; Rats | 1979 |
Adrenocortical carcinoma in a patient with systemic lupus erythematosus treated with azathioprine.
Topics: Adrenal Cortex Neoplasms; Azathioprine; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Neoplasm Metastasis; Phenobarbital; Phenytoin; Prednisone | 1979 |
Behavioral analysis of amygdaloid kindling in beagle dogs and the effects of clonazepam, diazepam, phenobarbital, diphenylhydantoin, and flunarizine on seizure manifestation.
Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Brain; Clonazepam; Diazepam; Dogs; Electric Stimulation; Phenobarbital; Phenytoin; Piperazines; Seizures; Status Epilepticus | 1979 |
Monitoring saliva anticonvulsant levels in children.
Topics: Anticonvulsants; Carbamazepine; Child; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Saliva | 1979 |
Brain uptake of phenytoin, phenobarbital, and diazepam.
Topics: Animals; Brain; Cats; Diazepam; Dogs; Kinetics; Phenobarbital; Phenytoin | 1979 |
Serum bilirubin and hepatic enzyme induction.
Topics: Adolescent; Adult; Aged; Bilirubin; Enzyme Induction; Humans; Liver; Middle Aged; Phenobarbital; Phenytoin; Time Factors | 1979 |
Effect of anticonvulsant drugs on the rate of folate catabolism in mice.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Female; Folic Acid; Male; Mice; Phenobarbital; Phenytoin; Pteroylpolyglutamic Acids | 1979 |
Decreased serum 24,25-dihydroxy vitamin D concentrations in children receiving chronic anticonvulsant therapy.
Topics: Adolescent; Calcium; Child; Child, Preschool; Chronic Disease; Dihydroxycholecalciferols; Humans; Hydroxycholecalciferols; Osteomalacia; Phenobarbital; Phenytoin; Phosphates; Seizures | 1979 |
[Studies of pharmacokinetics and disease information].
Topics: Adult; Animals; Diagnosis; Dogs; Female; Humans; Pharmaceutical Preparations; Phenobarbital; Phenytoin | 1979 |
Pharmacokinetic and pharmacodynamic tolerance of a new anticonvulsant agent (3-sulfamoylmethyl-1,2-benzisoxazole) compared to phenobarbital, diphenylhydantoin and carbamazepine in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Hexobarbital; Isoxazoles; Kinetics; Male; Oxazoles; Phenobarbital; Phenytoin; Proadifen; Rats; Sleep; Time Factors | 1979 |
Effects of pretreatment with phenobarbitone and phenytoin on the pharmacokinetics and toxicity of phenytoin on the pharmacokinetics and toxicity of misonidazole in mice.
Topics: Animals; Body Temperature; Body Weight; Brain; Drug Interactions; Half-Life; Lethal Dose 50; Liver; Male; Mice; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Phenobarbital; Phenytoin; Sleep; Transplantation, Homologous | 1979 |
Changes in heart rate associated with high-pressure convulsions in rodents.
Topics: Age Factors; Animals; Atmospheric Pressure; Atropine; Bradycardia; Female; Heart Rate; Mice; Phenobarbital; Phenytoin; Rats; Seizures; Syndrome | 1979 |
Interaction between plasma phenytoin and phenobarbital concentrations in epileptic patients.
Topics: Adult; Drug Interactions; Epilepsy; Female; Humans; Phenobarbital; Phenytoin | 1979 |
Serum levels of phenytoin and phenobarbital in epileptic patients treated with mixture antiepileptic tablets, Comital-L or Hydantol-F.
Topics: Anticonvulsants; Drug Combinations; Epilepsy; Humans; Mephobarbital; Phenobarbital; Phenytoin | 1979 |
[Quantitative analysis of EEG basic rhythms in epileptics (author's transl)].
Topics: Adult; Alpha Rhythm; Delta Rhythm; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Theta Rhythm | 1979 |
Effectiveness of simplified dosage schedules on the management of ambulant epileptic patients.
Topics: Adolescent; Adult; Ambulatory Care; Drug Administration Schedule; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1979 |
[Studies on the serum levels of the antiepileptic drugs-with particular reference to diphenylhydantoin, phenobarbital and carbamazepine-(author's transl)].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin | 1979 |
[Studies on the separation and photometric determination of antiepileptics (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Thin Layer; Humans; Mephobarbital; Methods; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet | 1979 |
Problems with the use of conventional anticonvulsant drugs in mentally retarded individuals.
Topics: Adolescent; Child; Child Behavior Disorders; Child, Preschool; Cognition; Epilepsy; Humans; Intellectual Disability; Motor Activity; Nervous System Diseases; Phenobarbital; Phenytoin | 1979 |
Plasma anticonvulsant concentrations during pregnancy.
Topics: Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1977 |
Evaluation of anticonvulsants in barbiturate withdrawal.
Topics: Animals; Anticonvulsants; Behavior, Animal; Cats; Dimethadione; Female; Humans; Male; Pentobarbital; Phenobarbital; Phenytoin; Seizures; Substance Withdrawal Syndrome; Time Factors; Trimethadione | 1977 |
Phenytoin, phospholipids, and calcium.
Topics: Animals; Brain; Calcium; Dose-Response Relationship, Drug; Humans; Phenobarbital; Phenytoin; Phosphatidylcholines; Phospholipids; Rabbits | 1977 |
Effect of benzhydryl piperazines, phenobarbital and phenytoin on maximal electroshock seizures in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Electroshock; Hindlimb; Humans; Male; Phenobarbital; Phenytoin; Piperazines; Rats; Reflex; Seizures; Stereotyped Behavior; Time Factors | 1977 |
Status epilepticus in pregnancy: effect of phenytoin malabsorption on seizure control.
Topics: Administration, Oral; Adult; Female; Humans; Intestinal Absorption; Phenobarbital; Phenytoin; Postpartum Period; Pregnancy; Pregnancy Complications; Status Epilepticus | 1978 |
Effect of anticonvulsants on plasma testosterone and sex hormone binding globulin levels.
Topics: Anticonvulsants; Carbamazepine; Epilepsy, Temporal Lobe; Female; Humans; Liver; Male; Phenobarbital; Phenytoin; Sex Factors; Sex Hormone-Binding Globulin; Testosterone | 1978 |
Controversies in the treatment of febrile convulsions.
Topics: Child; Epilepsy; Humans; Intelligence; Phenobarbital; Phenytoin; Prognosis; Seizures; Seizures, Febrile | 1979 |
Phenytoin hypersensitivity.
Topics: Drug Hypersensitivity; Humans; Phenobarbital; Phenytoin; Skin Diseases | 1977 |
Simultaneous gas chromatographic analysis for the seven commonly used antiepileptic drugs in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1977 |
[Methsuximide in the treatment of epilepsies (author's transl)].
Topics: Adolescent; Adult; Child; Drug Evaluation; Drug Interactions; Epilepsy; Gastrointestinal Diseases; Humans; Phenobarbital; Phenytoin; Succinimides | 1977 |
The hippocampal slice: a system for studying the pharmacology of seizures and for screening anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Penicillin G; Pentobarbital; Phenobarbital; Phenytoin; Seizures; Succinimides | 1977 |
Therapeutic monitoring of anticonvulsant drugs in psychiatric patients: rapid, simultaneous gas-chromatographic determination of six commonly used anticonvulsants without interference from other drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1978 |
Anticonvulsant induced increase in 25-hydroxy-vitamin D3-1alpha-hydroxylase.
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Alkaline Phosphatase; Animals; Calcium; Chickens; Enzyme Activation; Kidney; Male; Phenobarbital; Phenytoin; Steroid Hydroxylases | 1977 |
Phenytoin, phenobarbitone and serum cholesterol.
Topics: Adolescent; Adult; Cholesterol; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Vitamin D | 1977 |
[Consequeces of the elimination of a combination drug. Transition from combination antisacer: attention].
Topics: Adult; Drug Combinations; Epilepsy; Humans; Phenobarbital; Phenytoin | 1977 |
[Epilepsy and contraception].
Topics: Contraceptives, Oral; Contraceptives, Oral, Hormonal; Drug Interactions; Epilepsy; Female; Humans; Ovulation; Phenobarbital; Phenytoin; Pregnancy | 1977 |
Drug-protein binding and protein energy malnutrition.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Blood Proteins; Child; Digoxin; Humans; In Vitro Techniques; Kwashiorkor; Phenobarbital; Phenytoin; Protein Binding; Thiopental | 1977 |
[Selected clinical aspects of routine monitoring of anticonvulsant concentrations in serum (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Chromatography, Gas; Drug Therapy, Combination; Ethosuximide; Humans; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin | 1977 |
[A study on anticonvulsant level in body fluid. Ist report: serum level and drug interaction (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1977 |
Rickets in tuberous sclerosis from anticonvulsant drugs.
Topics: Adolescent; Anticonvulsants; Child; Humans; Male; Phenobarbital; Phenytoin; Rickets; Tuberous Sclerosis | 1977 |
[Chromosomal in study patients treated with anticonvulsant drugs].
Topics: Adolescent; Adult; Anticonvulsants; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1977 |
Factors influencing plasma carbamazepine concentrations.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Child, Preschool; Drug Interactions; Female; Humans; Infant; Infant, Newborn; Male; Mephobarbital; Middle Aged; Phenobarbital; Phenytoin | 1977 |
Pharmacological prophylaxis against the development of kindled amygdaloid seizures.
Topics: Acetazolamide; Amygdala; Animals; Cats; Dexamethasone; Electric Stimulation; Ethosuximide; Phenobarbital; Phenytoin; Seizures | 1977 |
A practical routine gas chromatographic determination of phenobarbital, primidone and diphenylhydantoin.
Topics: Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Spectrophotometry, Ultraviolet | 1978 |
Phenobarbital and diphenylhydantoin levels in neonates with seizures.
Topics: Administration, Oral; Female; Half-Life; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infusions, Parenteral; Male; Phenobarbital; Phenytoin; Seizures | 1978 |
Acute and chronic antiepileptic drug effect on the T complex interhemispheric latency difference.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Auditory Pathways; Brain; Child; Clonazepam; Electroencephalography; Epilepsy; Evoked Potentials; Functional Laterality; Humans; Middle Aged; Phenobarbital; Phenytoin; Reaction Time | 1978 |
Kinetics of carbamazepine and carbamazepine-epoxide, determined by use of plasma and saliva.
Topics: Adolescent; Adult; Carbamazepine; Drug Interactions; Epoxy Compounds; Female; Humans; Kinetics; Male; Middle Aged; Phenobarbital; Phenytoin; Saliva | 1978 |
Simultaneous gas liquid chromatographic dosage of phenobarbital and diphenylhydantoin in serum.
Topics: Chromatography, Gas; Epilepsy; Humans; Phenobarbital; Phenytoin | 1978 |
The toxicity of the major anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1978 |
[Labyrinthitis following the use of diphenylhydantoin].
Topics: Adult; Drug Therapy, Combination; Humans; Labyrinth Diseases; Labyrinthitis; Male; Phenobarbital; Phenytoin | 1978 |
The effects of dose, age, and sex on the serum levels of phenobarbital and diphenylhydantoin in epileptic patients.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Epilepsy; Female; Humans; Kinetics; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors | 1978 |
The stability and reliability of radioimmunoassays for clonazepam, diphenylhydantoin and phenobarbital in blood, serum or plasma.
Topics: Benzodiazepinones; Clonazepam; Cross Reactions; Drug Stability; Humans; Phenobarbital; Phenytoin; Radioimmunoassay; Time Factors | 1978 |
Influence of phenobarbital and diphenylhydantoin on the healing of rickets in the rat.
Topics: Animals; Calcification, Physiologic; Male; Phenobarbital; Phenytoin; Rats; Rickets; Vitamin D | 1978 |
Automation of diphenylhydantoin and phenobarbital measurements using the ABA-100 with emit reagents.
Topics: Autoanalysis; Computers; Humans; Phenobarbital; Phenytoin; Reagent Kits, Diagnostic | 1978 |
[Optimizing the therapeutic process in long-term antiepileptic therapy through the determination of drug levels in patients].
Topics: Anticonvulsants; Carbamazepine; Drug Therapy; Epilepsy; Ethosuximide; Germany, East; Humans; Methods; Phenobarbital; Phenytoin | 1978 |
Hypocalcaemia and secondary hyperparathyroidism in institutionalised mentally-retarded patients receiving anticonvulsant drugs: a survey of 292 patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Female; Humans; Hydroxycholecalciferols; Hyperparathyroidism, Secondary; Hypocalcemia; Intellectual Disability; Male; Middle Aged; Osteomalacia; Osteoporosis; Parathyroid Hormone; Phenobarbital; Phenytoin; Primidone; Radiography | 1978 |
Anticonvulsants and thyroid function.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine | 1978 |
[Determination of serum levels of phenobarbital and diphenylhydantoin in the treatment of epilepsy].
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin | 1978 |
[A study on anticonvulsant level in body fluids. 2nd report: Dialyzed serum (free form), CSF and saliva level (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Saliva | 1978 |
[Diphenylhydantoin and phenobarbital blood levels measured by gas-liquid chromatography (authors transl)].
Topics: Chromatography, Gas; Humans; Phenobarbital; Phenytoin | 1978 |
Compliance with anticonvulsant therapy in a hospital clinic and in the community.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Drug Prescriptions; Epilepsy; Female; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Saliva | 1978 |
Rapid quantitative method for the simultaneous determination of carbamazepine, carbamazepine-10,11-epoxide, diphenylhydantion, mephenytoin, phenobarbital and primidone in serum by thin-layer chromatography.
Topics: Carbamazepine; Chromatography, Thin Layer; Drug Combinations; Epoxy Compounds; Humans; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone | 1978 |
Antagonism of the anticonvulsant action of phenytoin, phenobarbital and acetazolamide by 6-hydroxydopamine.
Topics: Acetazolamide; Animals; Anticonvulsants; Brain Chemistry; Catecholamines; Electroshock; Hydroxydopamines; Male; Phenobarbital; Phenytoin; Rats | 1978 |
Determination of drugs in plasma by high-performance thin-layer chromatography.
Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desipramine; Humans; Imipramine; Nortriptyline; Phenobarbital; Phenytoin; Psychotropic Drugs; Spectrophotometry, Ultraviolet | 1978 |
Simultaneous gas chromatographic determination of diphenylhydantoin, carbamazepin (Tegretol), phenobarbital and primidone in presence of Kemadrin (procyclidine) and Prolixin (fluphenazine) in plasma of psychiatric patients.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Fluphenazine; Humans; Mental Disorders; Methods; Phenobarbital; Phenytoin; Primidone; Procyclidine; Pyrrolidines | 1978 |
Drug therapy of status epilepticus.
Topics: Acetazolamide; Diazepam; Humans; Lidocaine; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus | 1978 |
Simultaneous determination of diphenylhydantoin, mephobarbital, carbamazepine, phenobarbital and primidone in serum using direct chemical ionization mass spectrometry.
Topics: Anticonvulsants; Carbamazepine; Computers; Evaluation Studies as Topic; Humans; Mass Spectrometry; Mephobarbital; Methods; Palmitic Acids; Phenobarbital; Phenytoin; Primidone | 1978 |
Drug compliance and therapeutic considerations in 75 black epileptic children.
Topics: Adolescent; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Male; Patient Compliance; Phenobarbital; Phenytoin | 1978 |
Emergency gas-chromatographic assay of phenobarbital and phenytoin and liquid-chromatographic assay of theophylline.
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Emergencies; Humans; Phenobarbital; Phenytoin; Theophylline | 1978 |
Seizure susceptibility and anticonvulsant activity of carbamazepine, diphenylhydantoin and phenobarbital in rats with selective depletions of brain monoamines.
Topics: Animals; Anticonvulsants; Biogenic Amines; Brain; Carbamazepine; Electroshock; Female; Hydroxydopamines; Phenobarbital; Phenytoin; Rats; Seizures | 1978 |
Effect of anticonvulsant therapy on serum 25-hydroxyvitamin D level.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Humans; Hydroxycholecalciferols; Infant; Phenobarbital; Phenytoin | 1978 |
Improved gas-chromatographic analysis for anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Reference Standards | 1978 |
Interaction of chloramphenicol with phenytoin and phenobarbital. Case report.
Topics: Adult; Chloramphenicol; Drug Interactions; Humans; Kinetics; Male; Phenobarbital; Phenytoin | 1978 |
[Antiepileptic emergency therapy in the adult age].
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Diazepam; Emergencies; Epilepsy; Humans; Phenobarbital; Phenytoin; Status Epilepticus | 1978 |
Kinetics of drug interactions in the treatment of epilepsy.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethanol; Female; Humans; Kinetics; Male; Phenobarbital; Phenytoin; Pregnancy; Primidone; Salicylates | 1978 |
Rapid micro-method for the measurement of phenobarbitone, primidone and phenytoin in blood plasma or serum by gas-liquid chromatography.
Topics: Animals; Cattle; Chromatography, Gas; Chromatography, Liquid; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone; Time Factors | 1978 |
Errors in measuring drug concentrations.
Topics: Blood Chemical Analysis; Clinical Laboratory Techniques; Diagnostic Errors; Digoxin; Humans; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quality Control | 1978 |
Eruptive melanocytic naevi following severe bullous disease.
Topics: Child; Female; Humans; Male; Nevus, Pigmented; Phenobarbital; Phenytoin; Skin Neoplasms; Stevens-Johnson Syndrome | 1978 |
Anaesthetic death in a four-and-a-half-year-old Alsation.
Topics: Anesthesia, Intravenous; Animals; Dog Diseases; Dogs; Female; Heart Arrest; Phenobarbital; Phenytoin; Thiopental | 1978 |
Fetal hydantoin syndrome in triplets. A unique experiment of nature.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Epilepsy; Face; Female; Growth Disorders; Humans; Infant, Newborn; Limb Deformities, Congenital; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Skull; Triplets | 1978 |
[Blood levels of phenytoin and phenobarbital in epileptics treated with phenydantin and phenytoinum].
Topics: Drug Synergism; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin | 1978 |
Focal cerebral dysrhythmia--presenting as headache: report of a case.
Topics: Adolescent; Brain Diseases; Diagnosis, Differential; Electroencephalography; Female; Headache; Humans; Phenobarbital; Phenytoin | 1978 |
Elevation of seizure thresholds: a comparison of cerebellar stimulation, phenobarbital, and diphenylhydantoin.
Topics: Animals; Cerebellar Cortex; Cerebral Cortex; Electric Stimulation; Electroencephalography; Male; Pentylenetetrazole; Phenobarbital; Phenytoin; Rabbits; Seizures | 1978 |
Brain concentrations of carbamazepine and carbamazepine-10,11-epoxide in epileptic patients.
Topics: Adolescent; Brain; Carbamazepine; Child; Epilepsy; Epoxy Compounds; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1978 |
Serum phenytoin after Ethosuximide.
Topics: Child; Drug Therapy, Combination; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin | 1978 |
Preliminary report on the magnesium deficient rat as a model of epilepsy.
Topics: Age Factors; Animals; Disease Models, Animal; Epilepsy; Female; Magnesium Deficiency; Male; Phenobarbital; Phenytoin; Rats; Rodent Diseases; Sex Factors | 1978 |
The effect of phenobarbital pretreatment on the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl-1-nitrosourea (PCNU), and on the plasma p
Topics: Alkylating Agents; Animals; Biotransformation; Brain Neoplasms; Carmustine; Dexamethasone; Drug Interactions; In Vitro Techniques; Kinetics; Liver; Lomustine; Male; Methylprednisolone; Neoplasms, Experimental; Nitrosourea Compounds; Phenobarbital; Phenytoin; Rats; Rats, Inbred F344 | 1979 |
Simultaneous determination of phenytoin, phenobarbital and their para-hydroxylated metabolites in urine by reversed-phase high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Female; Humans; Hydroxylation; Methods; Phenobarbital; Phenytoin | 1979 |
[Simultaneous determination of antiepileptic drugs in clinical laboratories: Problems of quality control and standardization (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Evaluation Studies as Topic; Humans; Methods; Phenobarbital; Phenytoin; Primidone; Quality Control | 1979 |
Barbiturate and anticonvulsant treatment in relation to osteomalacia with haemodialysis and renal transplantation.
Topics: Adult; Alkaline Phosphatase; Barbiturates; Bone and Bones; Creatinine; Female; Humans; Kidney Transplantation; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Renal Dialysis | 1976 |
[Measurement of the blood concentration of antiepileptic drugs. II Special cases].
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1975 |
[Reflections on temporal epilepsy in the child].
Topics: Adolescent; Anticonvulsants; Epilepsy, Temporal Lobe; Humans; Male; Phenobarbital; Phenytoin; Social Behavior Disorders; Valproic Acid | 1976 |
Proposals on antiepileptic pharmacotherapy for use in developing countries.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Developing Countries; Diazepam; Epilepsy; Ethosuximide; Humans; Infant; Phenobarbital; Phenytoin; Valproic Acid | 1976 |
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Male; Phenobarbital; Phenylacetates; Phenytoin; Primidone; Probenecid | 1975 |
Criteria for selection of patients for neurosurgical treatment.
Topics: Adolescent; Age Factors; Child; Electroencephalography; Encephalitis; Epilepsies, Partial; Epilepsy; Epilepsy, Post-Traumatic; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Psychosurgery; Radiography; Radionuclide Imaging; Skull; Sturge-Weber Syndrome; Tuberous Sclerosis | 1975 |
Benign focal epilepsy of childhood. A follow-up study of 100 recovered patients.
Topics: Adolescent; Child; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Female; Follow-Up Studies; Humans; Infant; Male; Phenobarbital; Phenytoin; Pneumoencephalography; Prospective Studies; Retrospective Studies; Social Adjustment | 1975 |
Blood level estimation in phenytoin treatment of epilepsy.
Topics: Adult; Child; Chromatography, Gas; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
Osteomalacia presenting as chorea.
Topics: Adolescent; Alkaline Phosphatase; Chorea; Diagnosis, Differential; Epilepsy, Tonic-Clonic; Humans; Hypocalcemia; Male; Osteomalacia; Phenobarbital; Phenytoin; Phosphates; Vitamin D Deficiency | 1975 |
Anticonvulsant nature of marihuana smoking.
Topics: Adult; Cannabis; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Humans; Male; Phenobarbital; Phenytoin; Phytotherapy | 1975 |
Seizures in adolescents.
Topics: Adolescent; Anticonvulsants; Automobile Driving; Benzodiazepines; Carbamazepine; Diagnosis, Differential; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Female; Humans; Hysteria; Male; Phenobarbital; Phenytoin; Physical Exertion; Pregnancy; Primidone; Psychology, Adolescent | 1975 |
Diseases of the central nervous system: Epilepsy.
Topics: Age Factors; Diazepam; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Meningitis; Phenobarbital; Phenytoin | 1975 |
Isoniazid as an inhibitor of primidone metabolism.
Topics: Depression, Chemical; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Isoniazid; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Pyridoxine; Tuberculosis, Miliary | 1975 |
Sensible prescribing. XI.--Juvenile and adult epilepsy.
Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Clonazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
Effects of different dosages of anticonvulsant drugs on mental performance in patients with chronic epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Child; Chronic Disease; Dose-Response Relationship, Drug; Epilepsies, Partial; Epilepsy; Humans; Intelligence Tests; Memory; Middle Aged; Phenobarbital; Phenytoin; Primidone; Reaction Time | 1975 |
Lupus-scleroderma syndrome induced by ethosuximide.
Topics: Adolescent; Anemia; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Lupus Erythematosus, Systemic; Phenobarbital; Phenytoin; Prednisolone; Scleroderma, Systemic | 1975 |
Problems of childhood. Febrile fits.
Topics: Age Factors; Child, Preschool; Diazepam; Epilepsy, Tonic-Clonic; Female; Fever; Humans; Infant; Male; Phenobarbital; Phenytoin; Recurrence; Seizures; Sex Factors | 1976 |
Epilepsy: a controllable disease. Part 2. Drug therapy and nursing care.
Topics: Acute Disease; Adolescent; Anticonvulsants; Child; Epilepsy; Ethosuximide; Gingival Hyperplasia; Humans; Long-Term Care; Phenobarbital; Phenytoin; Primidone | 1976 |
Prophylaxis with diphenylhydantoin and phenobarbital and alumina-gel monkey model. I. Twelve months of treatment: seizure, EEG, blood, and behavioral data.
Topics: Aluminum Hydroxide; Animals; Behavior, Animal; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Follow-Up Studies; Haplorhini; Macaca mulatta; Male; Phenobarbital; Phenytoin; Reaction Time; Seizures | 1976 |
Prophylaxis with diphenylhydantoin and phenobarbital in alumina-gel monkey model. II. Fourth-month follow-up period: seizure, EEG, blood and behavioral data.
Topics: Aluminum Hydroxide; Animals; Behavior, Animal; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Follow-Up Studies; Haplorhini; Humans; Macaca mulatta; Male; Phenobarbital; Phenytoin; Seizures; Substance Withdrawal Syndrome; Time Factors | 1976 |
Acute anticonvulsant effects of diphenylhydantoin, phenobarbital, and carbamazepine: a combined electroclinical and serum level study in amygdaloid kindled cats and baboons.
Topics: Amygdala; Animals; Carbamazepine; Cats; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electric Stimulation; Haplorhini; Light; Male; Papio; Phenobarbital; Phenytoin; Seizures; Time Factors | 1976 |
Phenytoin and phenobarbitone plasma clearance during pregnancy.
Topics: Adult; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Time Factors | 1976 |
Congenital malformations in four siblings of a mother taking anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anticonvulsants; Child; Child, Preschool; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Pregnancy; Primidone; Trimethadione | 1976 |
Sodium valproate in the treatment of resistant epilepsy.
Topics: Adolescent; Adult; Alopecia; Anticonvulsants; Body Weight; Diarrhea; Drug Interactions; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Male; Nausea; Phenobarbital; Phenytoin; Valerates; Valproic Acid; Vomiting | 1976 |
Epilepsy and other seizure disorders in children: drug management.
Topics: Acetazolamide; Anticonvulsants; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides; Trimethadione | 1976 |
Interactions of phenytoin and phenobarbital in terms of order and temporal spacing of administration in monkeys.
Topics: Animals; Drug Interactions; Epilepsy; Half-Life; Haplorhini; Macaca mulatta; Male; Phenobarbital; Phenytoin | 1976 |
Anticonvulsant prolongation of survival in adult murine lymphocytic choriomeningitis. I. Drug treatment and virologic studies.
Topics: Animals; Anticonvulsants; Diazepam; Drug Evaluation, Preclinical; Lymphocytic Choriomeningitis; Lymphocytic choriomeningitis virus; Mice; Phenobarbital; Phenytoin | 1977 |
Spectrophotometric and polarographic analysis for phenobarbital, N-methylphenobarbital and N-methoxymethylphenobarbital in a mixture.
Topics: Methods; Phenobarbital; Phenytoin; Polarography; Spectrophotometry | 1977 |
Simultaneous determination of phenobarbitone, primidone and phenytoin in small samples of blood by gas-liquid chromatography.
Topics: Chromatography, Gas; Chromatography, Liquid; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Micro-scale anticonvulsant assay with use of nitrogen/phosphorus detector and on-column methylation compared with a macro-scale procedure involving flame-ionization detection.
Topics: Anticonvulsants; Chromatography, Gas; Flame Ionization; Humans; Methylation; Phenobarbital; Phenytoin; Primidone | 1977 |
[Binding of diphenylhydantoin and phenobarbital to serum proteins in therapeutical relevant concentrations in the newborn infants and adults].
Topics: Adult; Age Factors; Blood Proteins; Child; Humans; Infant, Newborn; Middle Aged; Phenobarbital; Phenytoin; Protein Binding | 1977 |
Anticonvulsant drug antagonism of delta9tetrahydrocannabinol-induced seizures in rabbits.
Topics: Animals; Anticonvulsants; Cannabidiol; Cannabinol; Carbamazepine; Diazepam; Dose-Response Relationship, Drug; Dronabinol; Ethosuximide; Female; Male; Phenobarbital; Phenytoin; Rabbits; Seizures; Time Factors | 1977 |
Neonatal hypocalcaemia after intrauterine exposure to anticonvulsant drugs.
Topics: Adult; Female; Humans; Hypocalcemia; Infant, Newborn; Infant, Newborn, Diseases; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Tetany | 1977 |
Plasma 1,25-dihydroxyvitamin D levels in patients receiving anticonvulsant drugs.
Topics: Adult; Alkaline Phosphatase; Calcium; Dihydroxycholecalciferols; Humans; Hydroxycholecalciferols; Intellectual Disability; Phenobarbital; Phenytoin; Phosphorus | 1977 |
Anticonvulsant activity of phenobarbital and phenytoin in combination.
Topics: Animals; Brain Chemistry; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Male; Phenobarbital; Phenytoin; Rats | 1977 |
[Liver damage after long-term administration of phenylethylbarbituric acid and diphenylhydantoin].
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Epilepsy; Humans; Leucyl Aminopeptidase; Liver Diseases; Phenobarbital; Phenytoin | 1977 |
Plasma levels of phenobarbital and phenytoin in epileptic outpatients.
Topics: Adolescent; Adult; Ambulatory Care; Child; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1977 |
Quantitative gas chromatographic analysis of barbiturates and hydantoins with quaternary ammonium hydroxides.
Topics: Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Quaternary Ammonium Compounds | 1977 |
Single or multiple daily doses of anticonvulsant drugs.
Topics: Child; Drug Administration Schedule; Humans; Phenobarbital; Phenytoin | 1977 |
Quality control in the simultaneous assay of anticonvulsants using an automated gas chromatographic system with a nitrogen detector.
Topics: Anticonvulsants; Chromatography, Gas; Humans; Methylation; Nitrogen; Phenobarbital; Phenytoin; Primidone; Quality Control | 1977 |
Convulsant-anticonvulsant interactions on seizure activity and cortical acetylcholine release.
Topics: Acetylcholine; Animals; Anticonvulsants; Bicuculline; Blood Pressure; Cerebral Cortex; Convulsants; Drug Interactions; Electroencephalography; Male; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Seizures; Time Factors; Trimethadione | 1977 |
Simultaneous determination of anticonvulsant drugs by gas-liquid chromatography.
Topics: Anticonvulsants; Chromatography, Gas; Ethosuximide; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Serum levels of anticonvulsants and haematological sequelae in black epileptics.
Topics: Adolescent; Adult; Aged; Black People; Child; Child, Preschool; Drug Combinations; Epilepsy; Erythrocytes; Female; Folic Acid; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1977 |
[Symptomatic treatment of epilepsy].
Topics: Anticonvulsants; Diazepam; Epilepsy; Humans; Phenobarbital; Phenytoin | 1977 |
Evidence of osteomalacia in an outpatient group of adult epileptics.
Topics: Adult; Aged; Diet; Epilepsy; Female; Humans; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Time Factors | 1977 |
Evaluation of a rapid gas-chromatographic method for the simultaneous quantitative determination of ethosuximide, phenyletheylmalonediamide, carbamazepine, phenobarbital, primidone and diphenylhydantoin in human serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Evaluation Studies as Topic; Humans; Methods; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1977 |
Effect of anticonvulsants on the uptake of 5-methyltetrahydrofolic acid by the choroid plexus in rabbits.
Topics: Animals; Choroid Plexus; Dinitrophenols; In Vitro Techniques; Phenobarbital; Phenytoin; Rabbits; Temperature; Tetrahydrofolates | 1977 |
Gas chromatographic on-column methylation technique for the simulataneous determination of antiepileptic drugs in blood.
Topics: Anticonvulsants; Chromatography, Gas; Ethosuximide; Methylation; Phenobarbital; Phenytoin; Primidone | 1977 |
[Determination of the blood levels of phenobarbital, primidone and diphenylhydantoin].
Topics: Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Primidone; Radioimmunoassay | 1977 |
A comparison of the teratogenic activity of the antiepileptic drugs carbamazepine, clonazepam, ethosuximide, phenobarbital, phenytoin, and primidone in mice.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Female; Fetus; Lethal Dose 50; Maternal-Fetal Exchange; Mice; Phenobarbital; Phenytoin; Pregnancy; Primidone; Teratogens | 1977 |
Lack of effect of clonazepam on serum levels of diphenylhydantoin, phenobarbital and carbamazepine.
Topics: Adolescent; Adult; Benzodiazepinones; Carbamazepine; Child; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1977 |
The effect of anticonvulsant drugs which induce liver microsomal enzymes on derived and ingested phenobarbitone levels.
Topics: Adolescent; Adult; Biotransformation; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1977 |
1,25-dihydroxycholecalciferol in renal osteodystrophy. Epiphysiolysis--anticonvulsant therapy.
Topics: Adolescent; Bone and Bones; Child, Preschool; Chronic Kidney Disease-Mineral and Bone Disorder; Dihydroxycholecalciferols; Epiphyses, Slipped; Humans; Hydroxycholecalciferols; Infant; Male; Phenobarbital; Phenytoin | 1977 |
Acetazolamide-accelerated anticonvulsant osteomalacia.
Topics: Acetazolamide; Adult; Anticonvulsants; Calcium; Epilepsy; Female; Humans; Mephobarbital; Osteomalacia; Phenobarbital; Phenytoin; Phosphates | 1977 |
Discrepancies in recommended dosage regimens of drugs.
Topics: Adult; Child; Humans; Phenobarbital; Phenytoin | 1977 |
The investigation of phenobarbitone, phenytoin and primidone in the death of epileptics.
Topics: Epilepsy; Forensic Medicine; Humans; Phenobarbital; Phenytoin; Primidone | 1977 |
[Biotransformation and its modification by barbiturates].
Topics: Binding Sites; Biotransformation; Drug Interactions; Enzyme Induction; Epilepsy; Humans; Liver; Liver Diseases; Phenobarbital; Phenytoin; Rifampin | 1977 |
[The anti-epileptic drugs].
Topics: Age Factors; Anticonvulsants; Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1977 |
Effects of phenytoin on the release of 14C-adenine derivatives.
Topics: Adenine; Animals; Astrocytoma; Brain Neoplasms; Carbamazepine; Cells, Cultured; Cerebral Cortex; Hypoxanthines; In Vitro Techniques; Inosine; Neuroblastoma; Ouabain; Phenobarbital; Phenytoin; Rats; Veratridine | 1977 |
Evaluation of a new immunoassay for determination of phenytoin and phenobarbital: results of a European collaborative control study.
Topics: Chromatography, Gas; Chromatography, Thin Layer; Glucosephosphate Dehydrogenase; Humans; Immunoassay; Leuconostoc; Phenobarbital; Phenytoin | 1977 |
Phenobarbital and phenytoin effects on somatosensory evoked potentials and spontaneous EEG in normal cat brain.
Topics: Animals; Cats; Electric Stimulation; Electroencephalography; Evoked Potentials; Phenobarbital; Phenytoin | 1977 |
The effects of anticonvulsants of FI performance in the rat.
Topics: Animals; Anticonvulsants; Conditioning, Operant; Diazepam; Phenobarbital; Phenytoin; Piperazines; Rats; Reinforcement Schedule | 1977 |
The behavioral and electrical interactions of electrically induced hippocampal seizures and four anticonvulsants.
Topics: Animals; Anticonvulsants; Conditioning, Operant; Diazepam; Electric Stimulation; Electroencephalography; Hippocampus; Male; Phenobarbital; Phenytoin; Piperazines; Rats; Reinforcement Schedule; Seizures; Time Factors | 1977 |
The metabolism of phenobarbitone, phenytoin and antipyrine in Black patients.
Topics: Adult; Antipyrine; Black People; Drug Interactions; Half-Life; Humans; Phenobarbital; Phenytoin; South Africa | 1977 |
Epilepsy.
Topics: Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin | 1977 |
Evaluation of serum levels during prolonged combination therapy with phenytoin and phenobarbitone.
Topics: Adult; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Time Factors | 1977 |
N-Acetyltryptophan ethyl ester: a new internal standard for the gas chromatographic determination of plasma anticonvulsant levels.
Topics: Anticonvulsants; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Tryptophan | 1977 |
Distribution of plasma phenobarbital, diphenylhydantoin and primidone levels in epileptic patients.
Topics: Adult; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1977 |
Skeletal status in mentally retarded patients on anticonvulsive therapy.
Topics: Absorptiometry, Photon; Adolescent; Adult; Anticonvulsants; Bone Development; Child; Female; Humans; Intellectual Disability; Male; Metacarpus; Phenobarbital; Phenytoin; Radius; Sex Factors | 1977 |
Experience with a clinical pharmacological service in a teaching hospital.
Topics: Education, Pharmacy; Hospitals, Teaching; Humans; Pharmacology; Pharmacy Service, Hospital; Phenobarbital; Phenytoin; South Africa | 1977 |
Influence of dietary cadmium and copper on the rachitogenic effect of some anticonvulsants in rats.
Topics: Animals; Bone and Bones; Cadmium; Calcium; Copper; Diet; Female; Male; Phenobarbital; Phenytoin; Rats; Rickets | 1977 |
Multiple vitamin deficiencies in association with chronic anticonvulsant therapy.
Topics: Anticonvulsants; Ascorbic Acid Deficiency; Avitaminosis; Beriberi; Child, Preschool; Female; Heart Diseases; Humans; Phenobarbital; Phenytoin; Primidone; Rickets | 1977 |
Effect of inline filtration on the potency of drugs administered intravenously.
Topics: Cephalothin; Dactinomycin; Dexamethasone; Digoxin; Drug Stability; Filtration; Infusions, Parenteral; Isoproterenol; Phenobarbital; Phenytoin | 1977 |
Comparison of six procedures for the simultaneous determination of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1977 |
Comparative activity of delta9-tetrahydrocannabinol, diphenylhydantoin, phenobarbital and chlordiazepoxide on electroshcok seizure threshold in mice.
Topics: Animals; Body Weight; Chlordiazepoxide; Dronabinol; Electroshock; Glucose; Male; Mice; Phenobarbital; Phenytoin; Seizures | 1977 |
Routine dual-wavelength analysis of anticonvulsant drugs by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin | 1977 |
Dupuytren's disease in epilepsy: result of prolonged administration of anticonvulsants.
Topics: Adult; Anticonvulsants; Dupuytren Contracture; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1976 |
Cardiac defects in children of mothers receiving anticonvulsant therapy during pregnancy.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Cleft Lip; Cleft Palate; Dimethadione; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Male; Mephobarbital; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Trimethadione | 1976 |
Simultaneous high-pressure liquid-chromatographic determination of some anticonvulsants in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1976 |
Microsomal enzyme inducers and hypervitaminosis A in rats.
Topics: Animals; Bone Diseases; Enzyme Induction; Female; Liver; Microsomes, Liver; Paralysis; Phenobarbital; Phenytoin; Pregnenolone Carbonitrile; Rats; Vitamin A; Zoxazolamine | 1976 |
Monitoring drug concentrations in a case of combined overdosage with primidone and methsuximide.
Topics: Adult; Computers; Female; Gas Chromatography-Mass Spectrometry; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone; Succinimides | 1976 |
Teratogenic effect of anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acetazolamide; Anticonvulsants; Child; Child, Preschool; Diazepam; Female; Humans; Infant; Male; Pedigree; Phenobarbital; Phenytoin; Pregnancy; Primidone | 1976 |
Anticonvulsant drug mechanisms. Phenytoin, phenobarbital, and ethosuximide and calcium flux in isolated presynaptic endings.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Ethosuximide; Female; In Vitro Techniques; Phenobarbital; Phenytoin; Procaine; Rabbits; Synaptosomes; Time Factors | 1976 |
Ascorbic acid concentrations in human plasma and cerebrospinal fluid [proceedings].
Topics: Ascorbic Acid; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1976 |
Simultaneous quantitative gas-chromatographic analysis of ethosuximide, phenobarbitone, primidone and diphenylhydantoin.
Topics: Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1976 |
Pharmacological influences on T4 to T3 conversion in rat liver.
Topics: Animals; Dexamethasone; Kinetics; Liver; Phenobarbital; Phenytoin; Rats; Thyroxine; Triiodothyronine | 1976 |
Antagonism of imipramine poisoning by anticonvulsants in the rat.
Topics: Animals; Anticonvulsants; Diazepam; Imipramine; Lethal Dose 50; Male; Phenobarbital; Phenytoin; Rats | 1976 |
Further observations on carbamazepine plasma levels in epileptic patients. Relationships with therapeutic and side effects.
Topics: Adult; Age Factors; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Humans; Male; Phenobarbital; Phenytoin | 1976 |
The convulsive profile of Cicuta douglasii (water hemlock).
Topics: Animals; Anticonvulsants; Convulsants; Electroshock; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Plant Extracts | 1976 |
Phenytoin and phenobarbital measurement by centrifugal analyzer.
Topics: Autoanalysis; Centrifugation; Methods; Phenobarbital; Phenytoin | 1976 |
High-speed liquid chromatographic determination of antiepileptic drugs in human plasma.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Microchemistry; Phenobarbital; Phenytoin | 1976 |
Quantitative determination of underivatized anti-convulsant drugs by high resolution gas chromatography with support-coated open tubular columns.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1976 |
Improved method for measurement of serum levels of phenobarbital, carbamazepine, primidone and diphenylhydantoin by gas-liquid chromatography.
Topics: Analysis of Variance; Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Temperature | 1976 |
Drug stimulated biotransformation of hormonal steroid contraceptives: clinical implications.
Topics: Ampicillin; Biotransformation; Carbamazepine; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Drug Interactions; Enzyme Induction; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Uterine Hemorrhage | 1976 |
Simultaneous gas chromatographic analysis for the four commonly used antiepileptic drugs in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ion Exchange Resins; Phenobarbital; Phenytoin; Primidone; Temperature | 1976 |
Anticonvulsant drugs and mental symptoms: a review.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Folic Acid Deficiency; Humans; Mental Disorders; Phenobarbital; Phenytoin; Psychoses, Substance-Induced; Schizophrenia | 1976 |
[Toxic epidermal necrolosys -- Lyell's syndrome in a patient protractedly treated by anti-epileptic agents].
Topics: Adult; Anticonvulsants; Barbiturates; Epilepsy; Humans; Male; Mephenytoin; Phenobarbital; Phenytoin; Stevens-Johnson Syndrome | 1976 |
Anticonvulsant-induced dyskinesias: a comparison with dyskinesias induced by neuroleptics.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cerebellar Diseases; Chorea; Dyskinesia, Drug-Induced; Extremities; Facial Muscles; Female; Humans; Male; Middle Aged; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Syndrome; Tranquilizing Agents; Tremor | 1976 |
[Interval therapy of febrile convulsions for the management of their prognosis. I. Methods and therapeutic advice for interval therapy of febrile convulsions].
Topics: Child, Preschool; Epilepsy; Humans; Infant; Periodicity; Phenobarbital; Phenytoin; Recurrence; Seizures; Seizures, Febrile | 1976 |
Clinical pharmacokinetics in infants and children.
Topics: Aging; Body Water; Carbamazepine; Child; Child, Preschool; Clindamycin; Dextropropoxyphene; Diazoxide; Dicloxacillin; Digoxin; Ethosuximide; Humans; Infant; Infant, Newborn; Kidney; Kinetics; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Sulfonamides; Tetracycline; Theophylline | 1976 |
Status epilepticus.
Topics: Adult; Amobarbital; Diazepam; Humans; Male; Phenobarbital; Phenytoin; Status Epilepticus | 1976 |
Binding of anticonvulsant drugs to cytochrome P-450: correlation with evidence of induction of hepatic microsomal enzymes.
Topics: Animals; Anticonvulsants; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Glucaric Acid; Hexobarbital; In Vitro Techniques; Kinetics; Male; Mephenytoin; Microsomes, Liver; Phenobarbital; Phenylbutyrates; Phenytoin; Rats; Receptors, Drug; Urea | 1976 |
The necessity of drug level monitoring in anticonvulsant drug therapy.
Topics: Body Weight; Dose-Response Relationship, Drug; Epilepsy; Humans; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1976 |
Acute (toxic) epidermal necrolysis. Report of a case.
Topics: Child, Preschool; Dextroamphetamine; Humans; Male; Mouth Diseases; Mouth Mucosa; Phenobarbital; Phenytoin; Stevens-Johnson Syndrome | 1975 |
Decreased capacity to metabolize diphenylhydantoin in a patient with hypersensitivity to warfarin.
Topics: Half-Life; Humans; Male; Metabolism, Inborn Errors; Middle Aged; Phenobarbital; Phenytoin; Warfarin | 1975 |
Absent vestibulo-ocular reflexes and acute supratentorial lesions.
Topics: Acute Disease; Adult; Amobarbital; Anticonvulsants; Brain Stem; Cerebral Arteries; Child; Cranial Sinuses; Drug Therapy, Combination; Eye Movements; Humans; Intracranial Arteriovenous Malformations; Intracranial Embolism and Thrombosis; Male; Phenobarbital; Phenytoin; Reflex, Abnormal; Subarachnoid Hemorrhage; Vestibular Function Tests; Vestibule, Labyrinth | 1975 |
Teratogenic activity of the antiepileptic drugs phenobarbital, phenytoin, and primidone in mice.
Topics: Animals; Cleft Palate; Drug Interactions; Female; Gestational Age; Leucovorin; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Pregnancy; Primidone; Teratogens | 1975 |
Antinuclear antibodies and lupus-like syndromes in children receiving anticonvulsants.
Topics: Adolescent; Adult; Antibodies, Antinuclear; Anticonvulsants; Child; Child, Preschool; Ethosuximide; Female; Humans; Infant; Lupus Erythematosus, Systemic; Male; Mephenytoin; Phenobarbital; Phenytoin; Seizures; Succinimides; Trimethadione | 1976 |
Effects of anticonvulsant drugs on the synthesis of DNA and protein by human bone marrow cells in vitro.
Topics: Bone Marrow; Bone Marrow Cells; DNA; Folic Acid; Humans; Leucine; Leucovorin; Phenobarbital; Phenytoin; Protein Biosynthesis; Thymidine | 1976 |
Letter: Sodium valproate in the treatment of intractable childhood epilepsy.
Topics: Diazepam; Drug Therapy, Combination; Epilepsy; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Valerates; Valproic Acid | 1975 |
Method for diphenylhydantoin and phenobarbital assay by gas chromatography.
Topics: Buffers; Chloroform; Chromatography, Gas; Chromatography, Thin Layer; Colorimetry; Epilepsy; Humans; Methaqualone; Phenobarbital; Phenytoin | 1975 |
The adverse effect of anticonvulsant therapy on renal allograft survival. A preliminary report.
Topics: Adolescent; Anticonvulsants; Cadaver; Child; Child, Preschool; Epilepsy; Ethosuximide; Humans; Kidney Transplantation; Phenobarbital; Phenytoin; Postoperative Complications; Transplantation, Homologous | 1976 |
Letter: Epanutin and isoniazid interaction.
Topics: Adult; Carbamazepine; Drug Interactions; Electroencephalography; Epilepsy; Ethambutol; Ethosuximide; Female; Humans; Isoniazid; Phenobarbital; Phenytoin; Rifampin | 1975 |
Anaesthesia and the epileptic pateint. A review.
Topics: Adult; Anesthesia, General; Anticonvulsants; Barbiturates; Central Nervous System; Child, Preschool; Drug Interactions; Electroencephalography; Enzyme Induction; Epilepsy; Female; Halothane; Humans; Inactivation, Metabolic; Ketamine; Male; Methohexital; Nitrous Oxide; Phenobarbital; Phenytoin; Protein Binding | 1975 |
Surgery of temporal lobe epilepsy.
Topics: Adolescent; Adult; Astrocytes; Brain Neoplasms; Cerebral Cortex; Child; Child, Preschool; Electroencephalography; Epilepsy, Temporal Lobe; Follow-Up Studies; Glioma; Hemiplegia; Humans; Infant; Intellectual Disability; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Socioeconomic Factors; Temporal Lobe | 1975 |
Unconjugated hyperbilirubinemia. Physiologic evaluation and experimental approaches to therapy.
Topics: Adult; Albumins; Animals; Bilirubin; Crigler-Najjar Syndrome; Ethosuximide; Female; Gilbert Disease; Glutethimide; Hemolysis; Humans; Hyperbilirubinemia; Liver; Phenobarbital; Phenytoin; Phototherapy; Plasmapheresis; Rats; Seizures | 1975 |
Flash-heater ethylation of some antiepileptic drugs.
Topics: Alkylation; Anticonvulsants; Evaluation Studies as Topic; Hot Temperature; Humans; Mephenytoin; Mephobarbital; Methylation; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
[Investigations of serum levels of drugs in children receiving anticonvulsant medication. I. General evaluation of serum concentrations of diphenylhydantoin, primidone and phenobarbitone (author's transl)].
Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Chromatography, Gas; Drug Therapy, Combination; Humans; Infant; Phenobarbital; Phenytoin; Primidone | 1975 |
[Investigations of serum levels of drugs in children receiving anticonvulsant medication. II. Clinical observations (author's transl)].
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Diazepam; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1975 |
Proceedings: Clinical pharmacokinetics of antiepileptic drugs. Quantitative variables of drug clearance used for the individual assessment of dosage regimens.
Topics: Anticonvulsants; Drug Interactions; Ethosuximide; Humans; Hydroxybutyrates; Phenobarbital; Phenytoin; Primidone | 1974 |
Gas chromatographic studies of phenobarbital and diphenylhydantoin after flash-heater alkylation.
Topics: Alkylation; Chromatography, Gas; Hot Temperature; Phenobarbital; Phenytoin | 1975 |
Improved method for the simultaneous determination of phenobarbital, primidone and diphenylhydantoin in patient's serum by gas-liquid chromatography.
Topics: Anticonvulsants; Chromatography, Gas; Drug Stability; Humans; Methods; Methylation; Phenobarbital; Phenytoin; Primidone | 1975 |
Anticonvulsant activities of delta-8 and delta-9 tetrahydrocannabinol and uridine.
Topics: Animals; Anticonvulsants; Cannabis; Dronabinol; Electroshock; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Plant Extracts; Seizures; Uridine | 1975 |
Clinical applications of gas chromatograph/mass spectrometer/computer systems.
Topics: Autoanalysis; Caffeine; Chromatography, Gas; Computers; Diazepam; Evaluation Studies as Topic; Female; Humans; Imides; Indicators and Reagents; Mass Spectrometry; Methods; Milk, Human; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Pregnancy; Theobromine; Time Factors | 1975 |
Drugs of abuse radioimmunoassay directory.
Topics: Amphetamine; Atropine; Barbiturates; Cannabis; Humans; Lysergic Acid Diethylamide; Mescaline; Morphine; Nicotine; Pentazocine; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Radioimmunoassay; Substance-Related Disorders | 1975 |
Anticonvulsant level in saliva, serum, and cerebrospinal fluid.
Topics: Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
Hepatic cholesterol synthesis in man: effect of diazepam and other drugs.
Topics: Acetates; Adolescent; Adult; Aged; Animals; Biopsy, Needle; Chlorpromazine; Cholesterol; Diazepam; Female; Humans; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Rats | 1975 |
Development and evaluation of method for simultaneous determination of phenobarbital and diphenylhydantoin in plasma by high-pressure liquid chromatography.
Topics: Chromatography; Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin | 1975 |
Chlormethiazole in status epilepticus--three cases.
Topics: Adult; Chlormethiazole; Diazepam; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin | 1975 |
Effects and complications of high efficiency dialysis.
Topics: Barbiturates; Blood Urea Nitrogen; Body Weight; Calcium; Creatinine; Edema; Headache; Humans; Hypotension; Kidneys, Artificial; Nausea; Phenobarbital; Phenytoin; Poisoning; Primidone; Renal Dialysis; Salicylates; Substance-Related Disorders; Ultrafiltration; Uremia; Uric Acid | 1975 |
Analysis of the action of CNS depressant drugs on somato-somatic reflexes in the cat.
Topics: Action Potentials; Anesthesia; Animals; Cats; Cerebellum; Chlorpromazine; Diazepam; Female; Male; Neurons, Afferent; Phenobarbital; Phenytoin; Reflex; Synapses | 1975 |
Differential attenuation of somatovisceral and viscerosomatic reflexes by diazepam, phenobarbital and diphenylhydantoin.
Topics: Animals; Cats; Diazepam; Electric Stimulation; Evoked Potentials; Female; Male; Phenobarbital; Phenytoin; Reflex; Splanchnic Nerves | 1975 |
[Editorial: To measure or not to measure--that is the question. Problems of measuring blood levels of drugs].
Topics: Digitalis Glycosides; Dose-Response Relationship, Drug; Humans; Lithium; Pharmaceutical Preparations; Phenobarbital; Phenylbutazone; Phenytoin; Salicylates | 1975 |
[Plasma concentration of phenytoin in epileptics--importance for the clinician].
Topics: Adult; Child; Chromatography, Gas; Dose-Response Relationship, Drug; Epilepsy; Humans; Medication Errors; Phenobarbital; Phenytoin; Spectrophotometry | 1975 |
Anticonvulsant osteomalacia.
Topics: Adolescent; Anticonvulsants; Bone and Bones; Humans; Male; Mephenytoin; Minerals; Osteomalacia; Phenobarbital; Phenytoin; Seizures; Vitamin D | 1975 |
Comparative enhancing effects of phenobarbital, amobarbital, diphenylhydantoin, and dichlorodiphenyltrichloroethane on 2-acetylaminofluorene-induced hepatic tumorigenesis in the rat.
Topics: 2-Acetylaminofluorene; Amobarbital; Animals; DDT; DNA, Neoplasm; Drug Synergism; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Organ Size; Phenobarbital; Phenytoin; Rats | 1975 |
Letter: Gas-chromatography of anticonvulsant drugs, with no solvent evaporation.
Topics: Anticonvulsants; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
A rapid gas-liquid chromatographic determination of serum levels of phenobarbital and diphenyllhydantoin.
Topics: Chromatography, Gas; Epilepsy; Humans; Microchemistry; Phenobarbital; Phenytoin | 1975 |
Drug interaction: diazoxide and diphenylhydantoin.
Topics: Administration, Oral; Adolescent; Child, Preschool; Chromatography, Gas; Diazoxide; Drug Therapy, Combination; Ethosuximide; Humans; Hyperinsulinism; Hypoglycemia; Infant; Injections, Intramuscular; Male; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Radioligand Assay; Seizures | 1975 |
Cognitive and motor-sensory performances in toxic and nontoxic epileptic subjects.
Topics: Adult; Attention; Cognition; Epilepsy; Female; Humans; Intelligence Tests; Male; Motor Skills; Phenobarbital; Phenytoin; Primidone; Psychological Tests; Sensation | 1975 |
Congenital malformations due to anticonvulsive drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anencephaly; Anticonvulsants; Birth Order; Cleft Lip; Cleft Palate; Epilepsy; Female; Fetal Death; Folic Acid; Folic Acid Antagonists; Hemorrhage; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Trimethadione | 1975 |
Unexpected, unexplained death in epileptic patients.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Death, Sudden; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1975 |
Photically induced epilepsy in Papio papio as a model for drug studies.
Topics: Acetylcholine; Animals; Carbamazepine; Clonazepam; Diazepam; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Glycine; Humans; Norepinephrine; Papio; Phenobarbital; Phenytoin; Photic Stimulation; Serotonin; Spasms, Infantile | 1975 |
Efficacy of standard anticonvulsants in monkey model with spontaneous motor seizures.
Topics: Aluminum; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Feeding Behavior; Humans; Macaca; Male; Motor Cortex; Phenobarbital; Phenytoin; Primidone; Reaction Time; Seizures; Substance Withdrawal Syndrome | 1975 |
Absorption and distribution of antiepileptic drugs.
Topics: Administration, Oral; Animals; Anticonvulsants; Capsules; Carbamazepine; Female; Humans; Injections, Intramuscular; Intestinal Absorption; Maternal-Fetal Exchange; Pharmaceutical Vehicles; Phenobarbital; Phenytoin; Pregnancy; Suppositories; Tablets, Enteric-Coated; Time Factors | 1975 |
Anticonvulsant drug blood levels.
Topics: Anticonvulsants; Ataxia; Diplopia; Drug Therapy, Combination; Epilepsy; Humans; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Uremia | 1975 |
[Polarographic determination of some phenylsubstituted anticonvulsants].
Topics: Anticonvulsants; Chromatography, Thin Layer; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Polarography; Primidone | 1975 |
The effect of anticonvulsants of FR performance in the rat.
Topics: Animals; Anticonvulsants; Conditioning, Operant; Diazepam; Male; Phenobarbital; Phenytoin; Rats; Reinforcement Schedule; Time Factors | 1975 |
[Nitration products of some phenyl-substituted anticonvulsants].
Topics: Anticonvulsants; Mephenytoin; Nitrogen; Phenobarbital; Phenytoin; Primidone | 1975 |
[Current viewpoints in drug treatment of epilepsy, with reference to the most common drugs in current use].
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Trimethadione | 1975 |
Temporal-lobe seizures with additional foci treated by resection.
Topics: Adolescent; Adult; Brain Neoplasms; Child; Electrodes, Implanted; Electroencephalography; Epilepsy, Temporal Lobe; Follow-Up Studies; Gliosis; Hamartoma; Humans; Middle Aged; Phenobarbital; Phenytoin; Syndrome; Temporal Lobe | 1975 |
Enzymatic immunoassay vs. gas/liquid chromatography for determination of phenobarbital and diphenylhydantoin in serum.
Topics: Chromatography, Gas; Humans; Immunoassay; Phenobarbital; Phenytoin | 1975 |
Bone mineral in mentally retarded patients receiving long-term anticonvulsive therapy.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Body Weight; Bone and Bones; Child; Female; Humans; Intellectual Disability; Locomotion; Male; Middle Aged; Minerals; Phenobarbital; Phenytoin; Radius; Sex Factors | 1975 |
Effects of diphenylhydantoin, phenobarbital, and diazepam on the metabolism of methylprednisolone and its sodium succinate.
Topics: Adult; Diazepam; Female; Half-Life; Humans; Liver; Male; Metabolic Clearance Rate; Methylprednisolone; Phenobarbital; Phenytoin; Sodium; Succinates | 1975 |
Plasma protein binding of drugs as a function of age in adult human subjects.
Topics: Adult; Aged; Aging; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Blood Proteins; Blood Urea Nitrogen; Humans; In Vitro Techniques; Middle Aged; Penicillin G; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Serum Globulins | 1975 |
Relationships among dose, serum and CSF levels and urinary output in fenobarbital and fenitoin treatment of epileptics.
Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin | 1975 |
Comparative study of proteins and lactic dehydrogenase isoenzymes in the blood and cerebrospinal fluid of nontreated and of phenobarbital and diphenylhydantoin treated epileptic patients.
Topics: Blood Proteins; Cerebrospinal Fluid Proteins; Epilepsy; Humans; Isoenzymes; L-Lactate Dehydrogenase; Phenobarbital; Phenytoin | 1975 |
Therapeutic response relationship to phenobarbital and diphenylhydantoin serum and cerebrospinal fluid levels in epileptics.
Topics: Adolescent; Adult; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin | 1975 |
Letter: Serum cholesterol and enzyme-inducing agents.
Topics: Cholesterol; Enzyme Induction; Humans; Microsomes; Phenobarbital; Phenytoin | 1975 |
Folate transport in the choroid plexus.
Topics: Animals; Biological Transport; Choroid Plexus; Dinitrophenols; Folic Acid; In Vitro Techniques; Kinetics; Oxygen; Phenobarbital; Phenytoin; Probenecid; Sodium; Swine; Tetrahydrofolates | 1975 |
Studies of the development of congenital anomalies in rats. III. Effects of inhibition of mitochondrial energy systems on embryonic development.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Chloramphenicol; Diet; Embryo Implantation; Energy Metabolism; Enzyme Inhibitors; Female; Fetus; Malonates; Mitochondria; Phenobarbital; Phenytoin; Pregnancy; Propylene Glycols; Rats; Teratogens | 1975 |
[Interest in the determination of drugs and their metabolites in clinical pharmacology and therapeutics].
Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antidepressive Agents, Tricyclic; Digitalis Glycosides; Dose-Response Relationship, Drug; Lithium; Pharmaceutical Preparations; Phenobarbital; Phenylbutazone; Phenytoin; Theophylline | 1975 |
Phenytoin and phenobarbital concentrations in saliva and plasma measured by radioimmunoassay.
Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Humans; Infant; Middle Aged; Phenobarbital; Phenytoin; Radioimmunoassay; Saliva | 1975 |
Thin-layer chromatographic determination of barbiturates and phenytoin in serum and blood.
Topics: Animals; Barbiturates; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Hexobarbital; Humans; Kinetics; Phenobarbital; Phenytoin; Rats | 1975 |
Folate and monoamine metabolism in epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Biogenic Amines; Epilepsy; Erythrocytes; Folic Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Middle Aged; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1975 |
Depression of immune competence by phenytoin and carbamazepine. Studies in vivo and in vitro.
Topics: Adolescent; Adult; Aged; Antibodies, Bacterial; Antibody Formation; Carbamazepine; Depression, Chemical; DNA; Dose-Response Relationship, Drug; Female; Humans; Hypersensitivity, Delayed; Immunoglobulin A; Immunosuppression Therapy; Lectins; Leukocyte Count; Leukocytes; Lymphocyte Activation; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Biosynthesis; RNA; Salmonella typhi; Sex Factors; Tetanus Toxoid | 1975 |
Psychosocial management of patients with complex partial seizures.
Topics: Adult; Alcoholism; Carbamazepine; Delivery of Health Care; Drug Administration Schedule; Epilepsy; Epilepsy, Temporal Lobe; Female; Fluphenazine; Humans; Male; Mental Disorders; Middle Aged; Neurocognitive Disorders; Patient Acceptance of Health Care; Phenobarbital; Phenytoin; Schizophrenia; Social Environment; Social Problems; Socioeconomic Factors; Syndrome | 1975 |
Epilepsy anticonvulsants and malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Heart Defects, Congenital; Humans; Mephobarbital; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Teratogens | 1975 |
Letter: Simple method for repetitive blood sampling in a self-controlled design in the rat.
Topics: Animals; Blood Specimen Collection; Drug Interactions; Phenobarbital; Phenytoin; Rats | 1975 |
Acute primidone overdosage with massive crystalluria.
Topics: Child; Chromatography, Gas; Crystallization; Epilepsy, Temporal Lobe; Female; Humans; Phenobarbital; Phenytoin; Primidone; Time Factors | 1975 |
Diphenylhydantoin, phenobarbital, and primidone in saliva, plasma, and cerebrospinal fluid.
Topics: Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
The influence of anticonvulsant drugs on cerebral aspartate aminotransferase activity in mice with predisposition to audiogenic seizures.
Topics: Acoustic Stimulation; Animals; Aspartate Aminotransferases; Brain; Mice; Phenobarbital; Phenytoin; Seizures | 1975 |
Brain concentrations of phenytoin, phenobarbitone and primidone in epileptic patients.
Topics: Adolescent; Adult; Brain Chemistry; Child; Child, Preschool; Chromatography, Gas; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
Changes in drug metabolism with increasing age: 2. phenytoin clearance and protein binding.
Topics: Adult; Aged; Aging; Female; Humans; Male; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin | 1975 |
Plasma level studies on different brands of sodium diphenylhydantoin (DPH) and primidone.
Topics: Biological Availability; Capsules; Epilepsy; Female; Humans; Kinetics; Male; Phenobarbital; Phenytoin; Primidone; Solubility; Tablets; Therapeutic Equivalency | 1975 |
[Problems in the use of anti-epileptics. 2. Resorption and the influence of resorption].
Topics: Animals; Anticonvulsants; Child; Epilepsy; Humans; Hydroxylation; Milk; Phenobarbital; Phenytoin; Powders; Time Factors; Water | 1975 |
Anticonvulsive properties of cinnarizine and flunarizine in rats and mice.
Topics: Animals; Anticonvulsants; Cinnarizine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Female; Lethal Dose 50; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Piperazines; Rats; Seizures; Time Factors | 1975 |
Methylation artifacts in the gas chromatography of serum extracts. Competitive suppression with trimethyl-d9 anilinium hydroxide.
Topics: Aniline Compounds; Chromatography, Gas; Indicators and Reagents; Mass Spectrometry; Methylation; Phenobarbital; Phenytoin; Phosphatidylcholines; Quaternary Ammonium Compounds | 1976 |
Discrepancies in recommended dosage regimens of drugs.
Topics: Adult; Epilepsy; Humans; Phenobarbital; Phenytoin | 1976 |
Letter: Failure to confirm anticonvulsant hypomagnesaemia.
Topics: Epilepsy; Humans; Magnesium Deficiency; Phenobarbital; Phenytoin | 1976 |
Correlation of the "EMIT" antiepileptic drug assay with a gas liquid chromatographic method.
Topics: Autoanalysis; Chromatography, Gas; Humans; Immunoassay; Phenobarbital; Phenytoin; Primidone | 1976 |
Interactions between phenytoin, phenobarbitone and other drugs.
Topics: Drug Interactions; Phenobarbital; Phenytoin | 1976 |
Interaction of quinidine with anticonvulsant drugs.
Topics: Adult; Arrhythmias, Cardiac; Depression, Chemical; Drug Interactions; Enzyme Induction; Epilepsy; Female; Half-Life; Humans; Kinetics; Male; Phenobarbital; Phenytoin; Prothrombin Time; Quinidine | 1976 |
Effects of diphenylhydantoin and phenobarbital on protein metabolism in the rat cerebral cortex.
Topics: Amino Acids; Animals; Cerebral Cortex; Kinetics; Leucine; Male; Nerve Tissue Proteins; Phenobarbital; Phenytoin; Rats | 1976 |
Simultaneous isothermal determination of diphenylhydantoin and phenobarbital serum levels by gas-liquid chromatography following flash-heater hexylation.
Topics: Humans; Phenobarbital; Phenytoin; Temperature | 1976 |
Anticonvulsant activity of delta9-tetrahydrocannabinol compared with three other drugs.
Topics: Animals; Anticonvulsants; Cannabis; Chlordiazepoxide; Dronabinol; Electroshock; Male; Mice; Nicotine; Pentylenetetrazole; Pharmaceutical Vehicles; Phenobarbital; Phenytoin; Seizures; Strychnine; Time Factors | 1976 |
Cerebral arterial dolichoectasia with seizure. Case report.
Topics: Adult; Cerebral Arterial Diseases; Dilatation, Pathologic; Hemiplegia; Humans; Male; Migraine Disorders; Phenobarbital; Phenytoin | 1976 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1976 |
[Dangers of drug combinations (author's transl)].
Topics: Anticoagulants; Barbiturates; Contraceptives, Oral, Hormonal; Drug Antagonism; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Humans; Imipramine; Intestinal Absorption; Monoamine Oxidase Inhibitors; Phenobarbital; Phenytoin; Psychoses, Substance-Induced; Rifampin | 1976 |
Letter: Effects of medication of plasma vitamin A concentrations.
Topics: Humans; Intellectual Disability; Isosorbide Dinitrate; Phenobarbital; Phenytoin; Thioridazine; Vitamin A | 1976 |
Interlaboratory variability in determination of plasma antiepileptic drug concentrations.
Topics: Anticonvulsants; Epilepsy; Ethosuximide; Humans; Laboratories; Phenobarbital; Phenytoin; Primidone; Quality Control; United States | 1976 |
Effect of some anticonvulsant drugs on depletion of folate in rats on a vitamin B12-deficient diet.
Topics: Animals; Dietary Proteins; Female; Folic Acid Deficiency; Formiminoglutamic Acid; Liver; Phenobarbital; Phenytoin; Rats; Vitamin B Deficiency | 1976 |
Simple febrile convulsions.
Topics: Cerebrospinal Fluid; Child, Preschool; Diazepam; Emergency Service, Hospital; Fever; Humans; Infant; Paraldehyde; Phenobarbital; Phenytoin; Seizures | 1976 |
Radioimmunoassay, enzyme immunoassay, spectrophotometry, and gas-liquid chromatography compared for determination of phenobarbital and diphenylhydantoin.
Topics: Chromatography, Gas; Cross Reactions; Enzymes; Epilepsy; Evaluation Studies as Topic; Humans; Immunoassay; Phenobarbital; Phenytoin; Radioimmunoassay; Spectrophotometry | 1976 |
Simultaneous gas-chromatographic analysis for phenobarbital, diphenylhydantoin, carbamazepine, and primidone in serum.
Topics: Carbamazepine; Chromatography, Gas; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone; Time Factors | 1976 |
Simultaneous measurement of phenobarbital, diphenylhydantoin, and primidone in blood by high-pressure liquid chromatography.
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin; Primidone | 1976 |
Rapid micromethod for measuring anticonvulsant drugs in serum by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Evaluation Studies as Topic; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1976 |
Rapid gas-chromatographic measurement of anticonvulsant drugs in serum.
Topics: Anticonvulsants; Chromatography, Gas; Evaluation Studies as Topic; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone; Time Factors | 1976 |
Adaptation of "EMIT" technique for serum phenobarbital and diphenylhydantoin assays to the miniature centrifugal analyzer.
Topics: Centrifugation; Enzymes; Evaluation Studies as Topic; Humans; Immunoassay; Microchemistry; Phenobarbital; Phenytoin | 1976 |
Ultramicro gas-chromatographic analysis for anticonvulsants, with use of a nitrogen-selective detector.
Topics: Chromatography, Gas; Humans; Microchemistry; Nitrogen; Phenobarbital; Phenytoin; Primidone | 1976 |
[Influence of neuropharmaca on hormonal contraception].
Topics: Adolescent; Adult; Anticonvulsants; Chlorpromazine; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Drug Synergism; Female; Humans; Menstruation; Menstruation Disturbances; Middle Aged; Phenobarbital; Phenytoin; Pregnancy; Promethazine; Psychotropic Drugs | 1976 |
Single-dose kinetics of primidone in human subjects: effect of phenytoin on formation and elimination of active metabolites of primidone, phenobarbital and phenylethylmalonamide.
Topics: Adult; Biotransformation; Half-Life; Humans; Male; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1992 |
Pharmacokinetic interaction of zonisamide in rats. Effect of other antiepileptics on zonisamide.
Topics: Administration, Oral; Animals; Anticonvulsants; Blood Proteins; Diethylcarbamazine; Drug Interactions; Erythrocytes; Half-Life; Isoxazoles; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Valproic Acid; Zonisamide | 1992 |
Effects of some GABAergic agents on quinine-induced seizures in mice.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Diazepam; Male; Mice; Mice, Inbred Strains; Muscimol; Phenobarbital; Phenytoin; Quinine; Receptors, GABA-A; Seizures | 1992 |
Effects of Ca2+ antagonists and antiepileptics on tetrodotoxin-sensitive Ca(2+)-conducting channels in isolated rat hippocampal CA1 neurons.
Topics: Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Diltiazem; Dizocilpine Maleate; Dose-Response Relationship, Drug; Flunarizine; Hippocampus; Kinetics; Neurons; Nicardipine; Phenobarbital; Phenytoin; Pyramidal Tracts; Rats; Rats, Wistar; Sodium; Tetrodotoxin; Valproic Acid; Verapamil | 1992 |
Effects of some calcium antagonists upon the activity of common antiepileptic compounds on sound-induced seizures in DBA/2 mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Body Temperature; Calcium Channel Blockers; Diltiazem; Drug Synergism; Flunarizine; Mice; Mice, Inbred DBA; Nimodipine; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Verapamil | 1992 |
Ring 14 chromosome with complex partial seizures: a case report.
Topics: Child; Chromosomes, Human, Pair 14; Electroencephalography; Epilepsy, Complex Partial; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Ring Chromosomes; Tomography, X-Ray Computed; Valproic Acid | 1992 |
Cerebral cavernous angioma: a potentially benign condition? Successful treatment in 16 cases.
Topics: Adolescent; Adult; Angiography; Brain Neoplasms; Carbamazepine; Cerebral Hemorrhage; Child; Epilepsy; Female; Hemangioma, Cavernous; Humans; Magnetic Resonance Imaging; Male; Phenobarbital; Phenytoin; Retrospective Studies; Seizures; Valproic Acid | 1992 |
Massive theophylline dosing in a heavy smoker receiving both phenytoin and phenobarbital.
Topics: Adult; Asthma; Drug Administration Schedule; Female; Humans; Phenobarbital; Phenytoin; Seizures; Smoking; Theophylline | 1992 |
"An analysis of epileptic patients nonresponsive to drugs".
Topics: Anticonvulsants; Carbamazepine; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Treatment Failure | 1992 |
Cognitive effects of antiepileptic drug discontinuation.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Epilepsy; Humans; Middle Aged; Neuropsychological Tests; Phenobarbital; Phenytoin; Psychomotor Performance; Valproic Acid | 1992 |
Long-term influence of anticonvulsant agents on calcitonin, parathyroid hormone and osteocalcin.
Topics: Adult; Anticonvulsants; Calcitonin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Long-Term Care; Male; Middle Aged; Osteocalcin; Parathyroid Hormone; Phenobarbital; Phenytoin | 1992 |
Liquid chromatographic analysis of phenobarbital, phenytoin, and theophylline.
Topics: Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Monitoring; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Quality Control; Reference Values; Theophylline | 1992 |
Age dependency of the susceptibility of rats to aminooxyacetic acid seizures.
Topics: Aging; Aminooxyacetic Acid; Animals; Anticonvulsants; Body Temperature; Brain; Carbamazepine; Clonazepam; Disease Susceptibility; Electroencephalography; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Organ Specificity; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Time Factors; Valproic Acid | 1992 |
Two-dimensional high-performance liquid chromatographic method to assay p-hydroxyphenylphenylhydantoin enantiomers in biological fluids and stereoselectivity of enzyme induction in phenytoin metabolism.
Topics: Acetone; Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Cimetidine; Dexamethasone; Diazepam; Enzyme Induction; Female; Ketoconazole; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Safrole; Sex Characteristics; Stereoisomerism; Sulfaphenazole | 1992 |
Interactions between clobazam and standard antiepileptic drugs in patients with epilepsy.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Retrospective Studies; Valproic Acid | 1992 |
Rapid and sensitive liquid chromatographic assay of mefenamic acid in plasma.
Topics: Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Hydrogen-Ion Concentration; Indomethacin; Ketoprofen; Least-Squares Analysis; Mefenamic Acid; Phenobarbital; Phenytoin; Salicylates; Salicylic Acid; Sensitivity and Specificity; Valproic Acid | 1992 |
Effects of anticonvulsant drugs on axonal conduction in mammalian corpus callosum.
Topics: Action Potentials; Animals; Anticonvulsants; Axons; Corpus Callosum; Female; Guinea Pigs; In Vitro Techniques; Male; Neural Conduction; Pentobarbital; Phenobarbital; Phenytoin; Rats | 1992 |
Effects of four common anticonvulsants on the high pressure nervous syndrome in the rat.
Topics: Animals; Carbamazepine; Diazepam; Drug Evaluation, Preclinical; High Pressure Neurological Syndrome; Male; Phenobarbital; Phenytoin; Premedication; Rats; Rats, Inbred Strains | 1992 |
Influence of length of treatment on the interaction between phenobarbital and phenytoin.
Topics: Adolescent; Adult; Drug Interactions; Drug Therapy, Combination; Humans; Middle Aged; Phenobarbital; Phenytoin | 1992 |
Grand mal status epilepticus.
Topics: Alcoholism; Anticonvulsants; Diazepam; Epilepsy, Tonic-Clonic; Ethanol; Humans; Lorazepam; Male; Middle Aged; Phenobarbital; Phenytoin; Substance Withdrawal Syndrome | 1992 |
Antiepileptic drug disposition during pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Valproic Acid | 1992 |
Epilepsy, antiepileptic drugs, and malformations in children of women with epilepsy: a French prospective cohort study.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Cohort Studies; Epilepsy; Female; Humans; Odds Ratio; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Prospective Studies; Valproic Acid | 1992 |
Antiepileptic drugs and teratogenesis in two consecutive cohorts: changes in prescription policy paralleled by changes in pattern of malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Drug Prescriptions; Epilepsy; Female; Humans; Infant; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 1992 |
Effects of long-term anticonvulsant therapy on copper, zinc, and magnesium in hair and serum of epileptics.
Topics: Adult; Anticonvulsants; Carbamazepine; Copper; Drug Therapy, Combination; Epilepsy, Generalized; Female; Hair; Humans; Long-Term Care; Magnesium; Male; Middle Aged; Phenobarbital; Phenytoin; Schizophrenia; Valproic Acid; Zinc | 1992 |
[Effect of anticonvulsants upon experimental limbic seizure status and regional cerebral blood flow in the hippocampus].
Topics: Animals; Anticonvulsants; Cats; Diazepam; Electroencephalography; Hippocampus; Isoxazoles; Phenobarbital; Phenytoin; Regional Blood Flow; Status Epilepticus; Valproic Acid; Zonisamide | 1992 |
Automated homogeneous liposome immunoassay systems for anticonvulsant drugs.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Fluorescence Polarization Immunoassay; Glucosephosphate Dehydrogenase; Humans; Immunoassay; Immunoenzyme Techniques; Liposomes; Phenobarbital; Phenytoin; Quality Control; Spectrophotometry | 1992 |
[Drug enhancement of cortisol and glucocorticoid metabolism].
Topics: Adrenal Insufficiency; Drug Interactions; Ephedrine; Half-Life; Humans; Hydrocortisone; Methylprednisolone; Phenobarbital; Phenytoin; Prednisolone; Rifampin | 1992 |
Anticonvulsant drug potentiation by glycine in maximal electroshock seizures is mimicked by D-serine and antagonized by 7-chlorokynurenic acid.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Glycine; Kynurenic Acid; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine | 1991 |
Influence of antiepileptic drugs on sleep patterns.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Brain; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Long-Term Care; Male; Phenobarbital; Phenytoin; Retrospective Studies; Sleep Deprivation; Sleep Stages; Valproic Acid | 1991 |
Balance and cognitive impairment in two epileptic patients before and after vagal nerve stimulation.
Topics: Adult; Carbamazepine; Cognition; Electric Stimulation Therapy; Epilepsy, Temporal Lobe; Humans; Male; Parkinson Disease; Phenobarbital; Phenytoin; Postural Balance; Reaction Time; Time Factors; Vagus Nerve; Valproic Acid | 1991 |
Increased teniposide clearance with concomitant anticonvulsant therapy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Chromatography, High Pressure Liquid; Drug Interactions; Female; Humans; Male; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide | 1992 |
Familial occurrence of hypersensitivity to phenytoin.
Topics: Adult; Animals; Carbamazepine; Drug Hypersensitivity; Female; Humans; In Vitro Techniques; Mice; Phenobarbital; Phenytoin | 1991 |
Performance of fluorescence polarisation immunoassay reagents for carbamazepine, phenytoin, phenobarbitone, primidone, and valproic acid on a Cobas Fara II analyser.
Topics: Anticonvulsants; Carbamazepine; Evaluation Studies as Topic; Fluorescence Polarization Immunoassay; Humans; Phenobarbital; Phenytoin; Primidone; Reference Standards; Valproic Acid | 1991 |
Clinical evaluation of five therapeutic drugs using dry film multilayer technology on the OPUS immunoassay system.
Topics: Carbamazepine; Evaluation Studies as Topic; Humans; Immunoassay; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Reference Standards; Sensitivity and Specificity; Theophylline; Valproic Acid | 1991 |
[Evaluation of the effectiveness of monotherapy in the treatment of epilepsy].
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Drug Evaluation; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
Reactive lymphohistiocytosis with recurrence in the optic chiasm.
Topics: Adrenal Cortex Hormones; Adult; Cranial Nerve Diseases; Histiocytosis, Non-Langerhans-Cell; Humans; Magnetic Resonance Imaging; Male; Optic Chiasm; Phenobarbital; Phenytoin; Recurrence; Seizures | 1991 |
Generalized pustulation as a manifestation of the anticonvulsant hypersensitivity syndrome.
Topics: Adult; Carbamazepine; Cross Reactions; Drug Eruptions; Facial Dermatoses; Humans; Male; Middle Aged; Neutrophils; Phenobarbital; Phenytoin; Pruritus; Scalp Dermatoses; Skin Diseases, Vesiculobullous; Syndrome; Urticaria | 1991 |
Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.
Topics: Animals; Baclofen; Carbamazepine; Cricetinae; Diazepam; Disease Models, Animal; Dystonia; gamma-Aminobutyric Acid; Mesocricetus; Mutation; Pentylenetetrazole; Phenobarbital; Phenytoin; Synaptic Transmission; Valproic Acid | 1991 |
Liver damage in long-term anticonvulsant therapy: a serological and histological study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Humans; Isoantigens; Liver; Liver Diseases; Male; Middle Aged; Phenobarbital; Phenytoin; Retrospective Studies; Valproic Acid | 1991 |
Plasma uric acid in patients receiving anticonvulsant monotherapy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Phenobarbital; Phenytoin; Prospective Studies; Uric Acid; Valproic Acid | 1991 |
Diazepam and intubation in emergency treatment of seizures in children.
Topics: Adolescent; Body Weight; Case-Control Studies; Child; Child, Preschool; Diazepam; Drug Therapy, Combination; Emergency Service, Hospital; Humans; Infant; Infant, Newborn; Intubation, Intratracheal; Logistic Models; Phenobarbital; Phenytoin; Reaction Time; Seizures | 1991 |
Short-term effects of administration of anticonvulsant drugs on free carnitine and acylcarnitine in mouse serum and tissues.
Topics: Animals; Anticonvulsants; Carbamazepine; Carnitine; Heart; In Vitro Techniques; Male; Mice; Muscles; Myocardium; Phenobarbital; Phenytoin; Prohibitins; Valproic Acid | 1991 |
Alteration of renal carnitine metabolism by anticonvulsant treatment.
Topics: Ammonia; Animals; Anticonvulsants; Carbamazepine; Carnitine; Male; Mice; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
[Effects of antiepileptic drugs on delivery and early childhood--comparison among mono-therapies of valproic acid, phenytoin, carbamazepine and phenobarbital].
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Birth Weight; Carbamazepine; Embryonic and Fetal Development; Epilepsy; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Labor, Obstetric; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Spinal Dysraphism; Valproic Acid | 1991 |
Reduction of serum carnitine concentrations during anticonvulsant therapy with phenobarbital, valproic acid, phenytoin, and carbamazepine in children.
Topics: Analysis of Variance; Carbamazepine; Carnitine; Child; Drug Combinations; Fatty Acids; Fatty Acids, Volatile; Humans; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1991 |
Epileptic patients refractory to drug therapy.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Immunoglobulin G; Immunoglobulins; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
Comparison of the effects of propylthiouracil, amiodarone, diphenylhydantoin, phenobarbital, and 3-methylcholanthrene on hepatic and renal T4 metabolism and thyroid gland function in rats.
Topics: Amiodarone; Animals; Body Weight; Cytochrome P-450 Enzyme System; Cytochromes b5; Glucuronosyltransferase; Kidney; Liver; Male; Methylcholanthrene; Microsomes, Liver; Organ Size; Oxygenases; Phenobarbital; Phenytoin; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1991 |
Effects of phenobarbital and phenytoin on cortical glial cells in culture.
Topics: Animals; Animals, Newborn; Benzodiazepinones; Cells, Cultured; Cerebral Cortex; Flunitrazepam; Mice; Neuroglia; Phenobarbital; Phenytoin; Radioligand Assay | 1991 |
Synthesis of mixed-functional-phase silica supports for liquid chromatography and their applications to assays of drugs in serum.
Topics: Carbamazepine; Chromatography, Liquid; Humans; Phenobarbital; Phenytoin; Silicon Dioxide | 1990 |
An ultrafiltrate of saliva collected in situ as a biological sample for diagnostic evaluation.
Topics: Carbamazepine; Humans; Phenobarbital; Phenytoin; Saliva; Specimen Handling; Ultrafiltration | 1991 |
Thanatophoric dwarfism; drugs and antenatal diagnosis; a case report.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Female; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy; Prenatal Diagnosis; Thanatophoric Dysplasia | 1991 |
Seizures: introduction and commentary.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
Intraindividual variability of carbamazepine, phenobarbital, and phenytoin concentrations in saliva.
Topics: Adult; Carbamazepine; Fluorescence Polarization Immunoassay; Humans; Male; Phenobarbital; Phenytoin; Saliva | 1991 |
Comparison of enzyme immunoassay and fluorescence polarization immunoassay as techniques for measuring anticonvulsant drugs on the same analytical instrument.
Topics: Carbamazepine; Fluorescence Polarization Immunoassay; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1991 |
Ability of unstimulated and phorbol-ester-stimulated human blood-monocyte-derived macrophages to metabolize drugs and its implications.
Topics: Chromatography, Ion Exchange; Furans; Humans; Macrophages; Monocytes; Phenobarbital; Phenytoin; Solvents; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1991 |
Effects of acute valproic acid administration on carnitine plasma concentrations in epileptic patients.
Topics: Adult; Ammonia; Carnitine; Epilepsy; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
Protein changes associated with cobalt-induced epileptic activity in rat cerebral cortex.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Cobalt; Electroencephalography; Epilepsy; Male; Motor Cortex; Nerve Tissue Proteins; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1991 |
[Convulsive status].
Topics: Diazepam; Humans; Lorazepam; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus | 1990 |
[Clinical use of pharmacologic monitoring at a hospital community].
Topics: Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Utilization; Humans; Phenobarbital; Phenytoin; Product Surveillance, Postmarketing; Spain; Theophylline; Valproic Acid | 1990 |
Carbamazepine metabolism in humans: effect of concurrent anticonvulsant therapy.
Topics: Administration, Oral; Adolescent; Adult; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Half-Life; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Valproic Acid | 1990 |
The inhibitory effect of anticonvulsants on human sperm motility: measured with a trans-membrane migration method.
Topics: Adult; Anticonvulsants; Carbamazepine; Cell Membrane; Depression, Chemical; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sperm Motility; Valproic Acid | 1990 |
Possible roles for frequent salivary antiepileptic drug monitoring in the management of epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Menstruation; Monitoring, Physiologic; Phenobarbital; Phenytoin; Pregnancy; Saliva | 1990 |
Simultaneous determination of six antiepileptic drugs by capillary gas chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Hydroxides; Phenobarbital; Phenytoin; Potassium; Potassium Compounds; Primidone; Valproic Acid | 1990 |
Anticonvulsant-responsive panic attacks with temporal lobe EEG abnormalities.
Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; Female; Humans; Male; Middle Aged; Neurocognitive Disorders; Neurologic Examination; Panic Disorder; Phenobarbital; Phenytoin | 1990 |
Determination of anticonvulsant drugs and methyl xanthine derivatives in serum by liquid chromatography with direct injection: column-switching method using a new internal-surface reversed-phase silica support as a precolumn.
Topics: Anticonvulsants; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Phenobarbital; Phenytoin; Primidone; Silicon Dioxide; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Xanthines | 1990 |
Direct serum injection high-performance liquid chromatographic method for the simultaneous determination of phenobarbital, carbamazepine and phenytoin.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1990 |
A simple and disposable visual measuring device to assay antiepileptic drugs from whole blood samples.
Topics: Anticonvulsants; Carbamazepine; Chromatography; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1990 |
Comparison of human, bovine, and newborn calf serum in the preparation of external quality assurance samples for therapeutic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, Gas; Chromatography, High Pressure Liquid; Fluorescence Polarization; Humans; Immunoassay; Immunoenzyme Techniques; Nephelometry and Turbidimetry; Phenobarbital; Phenytoin; Quality Control; Radioimmunoassay; Theophylline | 1990 |
Substantia nigra regulates action of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroencephalography; Ethosuximide; Male; Microinjections; Midazolam; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra; Trimethadione | 1990 |
Status epilepticus following the oral ingestion of cocaine in an infant.
Topics: Cocaine; Diagnosis, Differential; Diazepam; Electroencephalography; Emergencies; Humans; Infant; Male; Phenobarbital; Phenytoin; Status Epilepticus | 1990 |
[The effect of barbiturates and diphenylhydantoin on the mitotic activity of thymocytes and bone marrow cells in mice and rats].
Topics: Animals; Bone Marrow Cells; Male; Mice; Mitosis; Phenobarbital; Phenytoin; Rats; Thymus Gland | 1990 |
Rapid anti-epileptic drug assay.
Topics: Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Humans; Patient Compliance; Phenobarbital; Phenytoin; Valproic Acid | 1990 |
Selective response to carbamazepine in a case of organic mood disorder.
Topics: Aged; Carbamazepine; Depressive Disorder; Female; Humans; Neurocognitive Disorders; Phenobarbital; Phenytoin; Valproic Acid | 1990 |
Sensorineural hearing loss: a reversible effect of valproic acid.
Topics: Aged; Audiometry; Epilepsy, Temporal Lobe; Hearing Loss, Sensorineural; Humans; Male; Phenobarbital; Phenytoin; Remission, Spontaneous; Valproic Acid | 1990 |
Development of monoclonal antibodies for therapeutic drug monitoring.
Topics: Antibodies, Monoclonal; Anticonvulsants; Carbamazepine; Cross Reactions; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1990 |
Effects of age and antiepileptic drugs on plasma levels and kinetics of clobazam and N-desmethylclobazam.
Topics: Adolescent; Adult; Age Factors; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Child; Child, Preschool; Clobazam; Drug Therapy, Combination; Epilepsy; Humans; Infant; Phenobarbital; Phenytoin; Time Factors; Valproic Acid | 1990 |
Five epileptic cases who manifested psychotic states under the toxic levels of antiepileptic drugs.
Topics: Anticonvulsants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Psychoses, Substance-Induced | 1990 |
The effect of hepatic enzyme inducers on busulfan neurotoxicity and myelotoxicity.
Topics: Animals; Aroclors; Bone Marrow; Busulfan; Chlorodiphenyl (54% Chlorine); Enzyme Induction; Female; Liver; Mice; Mice, Inbred Strains; Nervous System; Phenobarbital; Phenytoin | 1990 |
Postmortem serum protein binding and brain concentrations of antiepileptic drugs in autoptic specimens from 45 epileptic patients.
Topics: Anticonvulsants; Blood Proteins; Brain; Carbamazepine; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Protein Binding; Valproic Acid | 1990 |
Analysis of the factors influencing anti-epileptic drug concentrations--carbamazepine.
Topics: Aging; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Phenobarbital; Phenytoin; Regression Analysis; Retrospective Studies; Valproic Acid | 1990 |
Analysis of the factors influencing anti-epileptic drug concentrations--valproic acid.
Topics: Adolescent; Adult; Aging; Aspartate Aminotransferases; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Regression Analysis; Retrospective Studies; Sex Factors; Valproic Acid | 1990 |
The use of free phenytoin levels in averting phenytoin toxicity.
Topics: Adult; Female; Humans; Phenobarbital; Phenytoin; Status Epilepticus | 1990 |
Temperature effects on the estimation of free levels of phenytoin carbamazepine and phenobarbitone.
Topics: Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Protein Binding; Temperature | 1990 |
Evaluation of the Ames Seralyzer for the determination of carbamazepine, phenobarbital, and phenytoin concentrations in saliva.
Topics: Carbamazepine; Evaluation Studies as Topic; Fluorescence Polarization Immunoassay; Humans; Phenobarbital; Phenytoin; Saliva | 1990 |
Changes in seizure threshold and aggression during chronic treatment with three anticonvulsants and on drug withdrawal.
Topics: Aggression; Animals; Anticonvulsants; Lorazepam; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Social Behavior; Substance Withdrawal Syndrome | 1990 |
Plasma level distribution, effect and toxicity of antiepileptic drugs among Ethiopian epileptics.
Topics: Adolescent; Adult; Child; Drug Therapy, Combination; Epilepsy; Ethiopia; Female; Humans; Male; Phenobarbital; Phenytoin | 1990 |
The stability of several compounds in formalin fixed tissues and formalin-blood solutions.
Topics: Carbon Monoxide; Carboxyhemoglobin; Cyanides; Desipramine; Diazepam; Drug Stability; Embalming; Fixatives; Formaldehyde; Humans; Liver; Phenobarbital; Phenytoin; Postmortem Changes | 1990 |
Phenobarbital hepatotoxicity in an 8-month-old infant.
Topics: Carbamazepine; Cell Survival; Chemical and Drug Induced Liver Injury; Humans; Infant; Lymphocytes; Male; Methylprednisolone; Phenobarbital; Phenytoin | 1990 |
Effects of anticonvulsants on hippocampus-generating seizures.
Topics: Animals; Anticonvulsants; Carbamazepine; Cats; Dose-Response Relationship, Drug; Electric Stimulation; Female; Hippocampus; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Seizures | 1990 |
Formation of cytotoxic metabolites from phenytoin, imipramine, desipramine, amitriptyline and mianserin by mouse and human hepatic microsomes.
Topics: 7-Alkoxycoumarin O-Dealkylase; Amitriptyline; Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Desipramine; Dibenzoxazepines; Enzyme Induction; Humans; Imipramine; Injections, Intraperitoneal; Male; Mianserin; Mice; Mice, Inbred CBA; Microsomes, Liver; Phenobarbital; Phenytoin | 1990 |
Influence of surgery and antiepileptic drugs on seizures symptomatic of cerebral tumours.
Topics: Adult; Anticonvulsants; Brain Neoplasms; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Postoperative Period | 1990 |
Serum protein binding of antiepileptic drugs in Sri Lankans.
Topics: Adolescent; Adult; Anticonvulsants; Blood Proteins; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Sri Lanka | 1990 |
Treating epilepsy in Malawi: lessons learned.
Topics: Adult; Child; Epilepsy; Follow-Up Studies; Humans; Malawi; Patient Education as Topic; Phenobarbital; Phenytoin; Public Relations; Surveys and Questionnaires | 1990 |
Diagnostic pitfalls associated with amoxapine overdose: a case report.
Topics: Amoxapine; Child; Dibenzoxazepines; Electroencephalography; Emergencies; Female; Humans; Phenobarbital; Phenytoin; Poisoning; Seizures | 1990 |
Relationship between mephenytoin oxidation polymorphism and phenytoin, methylphenytoin and phenobarbitone hydroxylation assessed in a phenotyped panel of healthy subjects.
Topics: Adult; Female; Humans; Hydantoins; Hydroxylation; Male; Mephenytoin; Oxidation-Reduction; Phenobarbital; Phenotype; Phenytoin | 1990 |
Pharmacokinetics of anticonvulsants in pregnancy: alterations in plasma protein binding.
Topics: Adult; Anticonvulsants; Blood Proteins; Carbamazepine; Epilepsy; Female; Humans; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1990 |
Effects induced by phenobarbital and phenytoin on the activity of pseudocholinesterase in serum and liver in the mouse.
Topics: Animals; Butyrylcholinesterase; Cholinesterases; Female; In Vitro Techniques; Liver; Mice; Phenobarbital; Phenytoin | 1990 |
Anticonvulsant drug mechanisms of action.
Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Clonazepam; Electroshock; gamma-Aminobutyric Acid; Humans; Ion Channels; Membrane Potentials; Mice; Neurons; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1985 |
The effects of lindane, DDT, and chlordecone on avoidance responding and seizure activity.
Topics: Animals; Avoidance Learning; Chlordecone; Chlordiazepoxide; DDT; Dose-Response Relationship, Drug; Hexachlorocyclohexane; Insecticides; Learning; Male; Memory; Phenobarbital; Phenytoin; Rats; Rats, Inbred F344; Seizures | 1987 |
The effect of repeated seizures on anticonvulsant drug response in the kindling model.
Topics: Animals; Brain; Carbamazepine; Kindling, Neurologic; Male; Membrane Potentials; Phenobarbital; Phenytoin; Rats; Seizures | 1987 |
Serum aspirin-esterase activity in epileptic patients receiving treatment with phenobarbital, phenytoin, carbamazepine and valproic acid.
Topics: Adult; Anticonvulsants; Aspirin; Carbamazepine; Epilepsy; Esterases; Female; Humans; Male; Phenobarbital; Phenytoin; Valproic Acid | 1989 |
A model for managing epilepsy in a rural community in Africa.
Topics: Epilepsy; Health Education; Health Services Administration; Humans; Malawi; Mobile Health Units; Outpatient Clinics, Hospital; Patient Acceptance of Health Care; Phenobarbital; Phenytoin; Rural Health | 1989 |
[Plasma determination of 7 common drugs by high performance liquid chromatography].
Topics: Anticonvulsants; Bronchodilator Agents; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Phenobarbital; Phenytoin; Theophylline; Valproic Acid | 1989 |
Carnitine deficiency associated with anticonvulsant therapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Carnitine; Cerebral Palsy; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1989 |
[Effects of anticonvulsants on cellular immunity].
Topics: Animals; Anticonvulsants; Cell Division; Cytotoxicity, Immunologic; Female; Immunity, Cellular; Interleukin-2; Killer Cells, Natural; Lymphocyte Activation; Lymphocytes; Mice; Phenobarbital; Phenytoin; Recombinant Proteins; T-Lymphocytes, Cytotoxic; Valproic Acid | 1989 |
Variations in protein binding of drugs in plasma and serum.
Topics: Anticonvulsants; Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Fluoroimmunoassay; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Protein Binding; Theophylline; Valproic Acid | 1989 |
Cost-effective assays for use in monitoring carbamazepine, phenobarbital, and phenytoin in serum.
Topics: Carbamazepine; Chromatography, Gas; Cost-Benefit Analysis; Fluoroimmunoassay; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Reference Standards | 1989 |
Effects of anticonvulsants on plasma levels and entero-hepatic circulation of valproic acid and on hepatic drug metabolizing enzyme activities in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Enterohepatic Circulation; Liver; Male; Phenobarbital; Phenytoin; Protein Binding; Rats; Rats, Inbred Strains; Valproic Acid | 1989 |
Serum free levels and evaluation anticonvulsant drug interactions.
Topics: Adult; Anticonvulsants; Drug Interactions; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Valproic Acid | 1989 |
Interaction between GABAergic anticonvulsants and the NMDA receptor antagonist MK 801 against MES- and picrotoxin-induced convulsions in rats.
Topics: Animals; Anticonvulsants; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Electroshock; Ethanol; Male; Motor Activity; Pentobarbital; Phenobarbital; Phenytoin; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Stereotyped Behavior | 1989 |
Effects of anticonvulsants on spontaneous epileptiform activity which develops in the absence of chemical synaptic transmission in hippocampal slices.
Topics: Animals; Anticonvulsants; Benzodiazepines; Carbamazepine; Cell Membrane Permeability; Epilepsy; Hippocampus; In Vitro Techniques; Ion Channels; Midazolam; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1985 |
Simultaneous quantitation of salivary carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbitone by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Saliva; Spectrophotometry, Ultraviolet | 1989 |
Dosing accuracy of antiepileptic drug regimens as determined by serum concentrations in outpatient epilepsy clinic patients.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Outpatients; Phenobarbital; Phenytoin | 1989 |
[What the data on utilization of antiepileptic agents reveals].
Topics: Anticonvulsants; Czechoslovakia; Drug Combinations; Drug Utilization; Humans; Phenobarbital; Phenytoin; Schools, Medical | 1989 |
[Effects of phenobarbital and phenytoin on hippocampus generating seizures].
Topics: Amygdala; Animals; Cats; Hippocampus; Kindling, Neurologic; Phenobarbital; Phenytoin; Seizures | 1989 |
Daily salivary anticonvulsant monitoring in patients with intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Saliva | 1989 |
[Dosage adjustment of drugs during continuous hemofiltration. Results and practical consequences of a prospective clinical study].
Topics: Adult; Aged; Cefotaxime; Ceftazidime; Digitoxin; Digoxin; Hemofiltration; Humans; Imipenem; Kidney Failure, Chronic; Metronidazole; Middle Aged; Netilmicin; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Theophylline; Tobramycin; Vancomycin | 1989 |
Evaluation of Ames Seralyzer for the therapeutic drug monitoring of phenobarbital and phenytoin.
Topics: Adolescent; Child; Child, Preschool; Fluorescence Polarization; Fluorescent Antibody Technique; Humans; Infant; Monitoring, Physiologic; Phenobarbital; Phenytoin; Photometry | 1989 |
A micromethod for the estimation of free levels of anticonvulsant drugs in serum.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Fluorescence Polarization; Fluorescent Antibody Technique; Humans; Microchemistry; Phenobarbital; Phenytoin; Reference Standards; Reproducibility of Results; Ultrafiltration | 1989 |
Effects of phenytoin and phenobarbital on schedule-controlled responding and seizure activity in the amygdala-kindled rat.
Topics: Amygdala; Animals; Conditioning, Operant; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Rats; Reinforcement, Psychology; Seizures | 1989 |
Barbiturate-related connective tissue disorders.
Topics: Adult; Aged; Anticonvulsants; Barbiturates; Carbamazepine; Connective Tissue Diseases; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1989 |
Correlated ultrastructural damage between cerebellum cells after early anticonvulsant treatment in mice.
Topics: Animals; Animals, Newborn; Anticonvulsants; Cerebellum; Dose-Response Relationship, Drug; Mice; Microscopy, Electron; Mitochondria; Phenobarbital; Phenytoin | 1989 |
Cancer among epileptic patients exposed to anticonvulsant drugs.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Brain Neoplasms; Child; Child, Preschool; Denmark; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Length of Stay; Lung Neoplasms; Male; Middle Aged; Neoplasms; Phenobarbital; Phenytoin; Risk; Thorium Dioxide | 1989 |
Rapid sequential phenobarbital treatment of neonatal seizures.
Topics: Dose-Response Relationship, Drug; Gestational Age; Humans; Infant, Newborn; Lorazepam; Phenobarbital; Phenytoin; Seizures | 1989 |
Clinical and EEG response to anticonvulsants in neonatal seizures.
Topics: Anticonvulsants; Diazepam; Electroencephalography; Epilepsy; Humans; Infant, Newborn; Paraldehyde; Phenobarbital; Phenytoin; Prospective Studies | 1989 |
Saliva monitoring of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Saliva | 1989 |
Value of saliva anticonvulsant monitoring in pregnancy and the newborn.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Infant, Newborn; Monitoring, Physiologic; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva | 1989 |
Comparison of intraosseous and intravenous routes of anticonvulsant administration in a porcine model.
Topics: Animals; Blood Pressure; Bone Marrow; Fluorescence Polarization; Heart Rate; Immunoassay; Injections; Injections, Intravenous; Phenobarbital; Phenytoin; Swine; Tibia; Time Factors | 1989 |
The effect of anticonvulsants on the dexamethasone suppression test.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Carbamazepine; Depressive Disorder; Dexamethasone; Epilepsy; Humans; Hydrocortisone; Phenobarbital; Phenytoin | 1989 |
Pharmacokinetics and clinical use of parenteral phenytoin, phenobarbital, and paraldehyde.
Topics: Humans; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus | 1989 |
Effect of aminophylline upon the protective activity of common antiepileptic drugs and their plasma levels in mice.
Topics: Aminophylline; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Male; Mice; Phenobarbital; Phenytoin; Seizures | 1989 |
Effects of intranigral application of clinically-effective anticonvulsants on electroshock-induced seizures.
Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Electroshock; Hindlimb; Injections; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra | 1989 |
Parallel induction of plasma alpha 1-acid glycoprotein concentration and antipyrine clearance by drugs.
Topics: Animals; Antipyrine; Chromatography, Gas; Colorimetry; Cytochrome P-450 Enzyme System; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Liver; Male; Metabolic Clearance Rate; Orosomucoid; Phenobarbital; Phenytoin | 1989 |
[Mechanism of action of antiepileptic drugs].
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; gamma-Aminobutyric Acid; Ion Exchange; Phenobarbital; Phenytoin; Receptors, Neurotransmitter; Synaptic Transmission; Valproic Acid | 1987 |
[Spin immunoassay].
Topics: Electron Spin Resonance Spectroscopy; Humans; Immunoassay; Morphine; Phenobarbital; Phenytoin; Testosterone | 1987 |
Automated determination of drugs in serum by liquid chromatography with column-switching. I. Separation of antiepileptic drugs and metabolites.
Topics: Acetonitriles; Anticonvulsants; Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Perchlorates; Phenobarbital; Phenytoin; Quality Control; Regression Analysis; Statistics as Topic; Trichloroacetic Acid; Valproic Acid | 1988 |
Differential effects of anticonvulsants on developing neurons in vitro.
Topics: Animals; Anticonvulsants; Binding, Competitive; Carbamazepine; Cells, Cultured; Chick Embryo; Immunohistochemistry; Neurons; Phenobarbital; Phenytoin; Receptors, Cell Surface; Receptors, Nerve Growth Factor; Valproic Acid | 1988 |
Antiepileptic drugs and cerebral glucose metabolism.
Topics: Anticonvulsants; Brain; Carbamazepine; gamma-Aminobutyric Acid; Glucose; Humans; Phenobarbital; Phenytoin; Receptors, GABA-A; Tomography, Emission-Computed | 1988 |
The NMDA-receptor antagonist, MK-801, suppresses limbic kindling and kindled seizures.
Topics: Amygdala; Animals; Anticonvulsants; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Ketamine; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
Serum 5'-nucleotidase in patients receiving anti-epileptic drugs.
Topics: 5'-Nucleotidase; Adolescent; Adult; Age Factors; Aged; Alkaline Phosphatase; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Male; Middle Aged; Nucleotidases; Phenobarbital; Phenytoin; Sex Factors | 1985 |
Effects of anticonvulsant drugs on brain cultures from chick embryos: a comparison with cultures from embryos treated in ovo.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Brain; Carbonic Anhydrases; Cells, Cultured; Chick Embryo; Choline O-Acetyltransferase; gamma-Aminobutyric Acid; Kinetics; Neurons; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
Inhibition of metabolic cooperation by the anticonvulsants, diphenylhydantoin and phenobarbital.
Topics: Animals; Cell Communication; Cell Line; Cell Survival; Cricetinae; Cricetulus; Drug Interactions; Drug Resistance; Lung; Phenobarbital; Phenytoin; Thioguanine | 1985 |
Comparison of fluorescence polarization immunoassay and high performance liquid chromatography for the quantitative determination of phenytoin, phenobarbitone and carbamazepine in serum.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Fluorescence Polarization; Humans; Immunoassay; Phenobarbital; Phenytoin; Quality Control | 1986 |
On the modulating effects of temperature, albumin, pH and calcium on the free fractions of phenobarbitone and phenytoin.
Topics: Calcium; Dialysis; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Serum Albumin; Temperature | 1986 |
Rapid and sensitive determination of ethotoin as well as carbamazepine, phenobarbital, phenytoin and primidone in human serum.
Topics: Carbamazepine; Gas Chromatography-Mass Spectrometry; Humans; Hydantoins; Kinetics; Phenobarbital; Phenytoin; Powders; Primidone; Tablets | 1986 |
Dystrophic symptoms prevented by phenobarbital in avian muscular dystrophy.
Topics: Age Factors; Animals; Central Nervous System Depressants; Central Nervous System Stimulants; Chickens; Muscles; Muscular Dystrophy, Animal; Phenobarbital; Phenytoin | 1987 |
Factors that affect the induction of gamma glutamyltransferase in epileptic patients receiving anti-convulsant drugs.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Sex Factors | 1987 |
Comparison of basal glutathione S-transferase activities and of the influence of phenobarbital, butylated hydroxy-anisole or 5,5'-diphenylhydantoin on enzyme activity in male rodents.
Topics: Animals; Butylated Hydroxyanisole; Cricetinae; Cytosol; Glutathione Transferase; Liver; Male; Mesocricetus; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Species Specificity | 1987 |
Variable patterns in anticonvulsant drug-induced malformations in mice: comparisons of phenytoin and phenobarbital.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Growth Retardation; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Pregnancy; Species Specificity | 1987 |
Evaluation of the Ames Seralyzer for therapeutic drug monitoring of phenobarbital and phenytoin.
Topics: Evaluation Studies as Topic; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin | 1989 |
Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Chlorpromazine; Diazepam; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Male; Phenobarbital; Phenytoin; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1986 |
Nursing interventions for anticonvulsant drug interactions.
Topics: Anticonvulsants; Biotransformation; Carbamazepine; Drug Interactions; Humans; Nursing Care; Patient Education as Topic; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1986 |
Zinc status and delayed cutaneous hypersensitivity in handicapped children treated with anticonvulsants.
Topics: Adolescent; Child; Child, Preschool; Dinitrochlorobenzene; Disabled Persons; Drug Hypersensitivity; Female; Hair; Humans; Hypersensitivity, Delayed; Male; Phenobarbital; Phenytoin; Skin Tests; Zinc | 1987 |
Hypersensitivity reaction to anticonvulsants following head injury.
Topics: Adolescent; Brain Injuries; Drug Eruptions; Humans; Male; Phenobarbital; Phenytoin | 1987 |
[Effects of phenobarbital and phenytoin on the growth morphology and some ATPase activities of rat brain astrocytes derived from normal newborn cerebrum and C6 glioma cells in culture].
Topics: Adenosine Triphosphatases; Animals; Astrocytes; Brain; Cell Division; Cells, Cultured; Glioma; Phenobarbital; Phenytoin; Rats; Tumor Cells, Cultured | 1988 |
Different actions of vitamin D2 and D3 on bone metabolism in patients treated with phenobarbitone/phenytoin.
Topics: Adult; Alkaline Phosphatase; Bone and Bones; Calcium; Cholecalciferol; Double-Blind Method; Epilepsy; Ergocalciferols; Humans; Hydroxyproline; Middle Aged; Parathyroid Hormone; Phenobarbital; Phenytoin | 1985 |
Prolonged CNS hyperexcitability in mice after a single exposure to delta-9-tetrahydrocannabinol.
Topics: Animals; Central Nervous System; Dronabinol; Drug Tolerance; Electroshock; Male; Mice; Phenobarbital; Phenytoin; Psychomotor Disorders; Seizures; Substance Withdrawal Syndrome | 1986 |
Different metabolism of vitamin D2/D3 in epileptic patients treated with phenobarbitone/phenytoin.
Topics: 24,25-Dihydroxyvitamin D 3; 25-Hydroxyvitamin D 2; Adult; Aged; Calcifediol; Calcium; Cholecalciferol; Dihydroxycholecalciferols; Epilepsy; Ergocalciferols; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1986 |
Brain neurotransmitter receptor alterations in offspring of rats exposed to phenobarbital, phenytoin or their combination during pregnancy.
Topics: Animals; Brain; Cerebral Cortex; Corpus Striatum; Diazepam; Female; Fetus; Kinetics; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Serotonin; Spiperone | 1987 |
[The correlation between concentrations of anticonvulsive drugs in the brain and various parameters of maximal electroshock seizures in mice].
Topics: Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Drug Evaluation, Preclinical; Electroshock; Humans; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1986 |
Carbamazepine, phenytoin and phenobarbital in drug-resistant partial epilepsies.
Topics: Adolescent; Adult; Carbamazepine; Drug Evaluation; Drug Resistance; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1986 |
Antiepileptic effects of globulin-N, an intact human immunoglobulin and its tissue-distribution in kindled cats.
Topics: Amygdala; Animals; Anticonvulsants; Autoradiography; Cats; Drug Combinations; Epilepsy; Half-Life; Immunochemistry; Immunoglobulin A; Immunoglobulin G; Immunoglobulins, Intravenous; Kindling, Neurologic; Ovum; Pentylenetetrazole; Phenobarbital; Phenytoin; Time Factors; Tissue Distribution | 1986 |
Therapeutic drug monitoring in patients with chronic renal failure: evaluation of the Abbott TDx drug assay system.
Topics: Carbamazepine; Cross Reactions; Digoxin; Gentamicins; Humans; Immunoassay; Kidney Failure, Chronic; Lidocaine; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Valproic Acid; Vancomycin | 1986 |
Phenylethylmalonamide serum levels in patients treated with primidone and the effects of other antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Malonates; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Valproic Acid | 1986 |
Modulation of the behavioral effects of anticonvulsant drugs by an external discriminative stimulus in the pigeon.
Topics: Animals; Anticonvulsants; Columbidae; Conditioning, Operant; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Phenobarbital; Phenytoin; Probability; Reinforcement Schedule; Valproic Acid | 1986 |
A comparative study of the relative influence of different anticonvulsant drugs, UV exposure and diet on vitamin D and calcium metabolism in out-patients with epilepsy.
Topics: Adult; Calcium; Carbamazepine; Diet; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Ultraviolet Rays; Valproic Acid; Vitamin D | 1986 |
Genetic differences in anticonvulsant sensitivity in mouse lines selectively bred for ethanol withdrawal severity.
Topics: Alcohol Withdrawal Delirium; Alcohols; Animals; Anticonvulsants; Diazepam; Disease Susceptibility; Electroshock; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Psychoses, Alcoholic; Valproic Acid | 1986 |
Effects of anticonvulsant drugs on substantia nigra pars reticulata neurons.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Ethosuximide; Male; Neurons; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Substantia Nigra; Trimethadione; Valproic Acid | 1986 |
Synergistic effects of oxiracetam and piracetam in combination with antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Drug Synergism; Drug Therapy, Combination; Epilepsy; Male; Phenobarbital; Phenytoin; Piracetam; Pyrrolidines; Pyrrolidinones; Rats; Valproic Acid | 1986 |
Lack of hepatotoxic interaction between the anticonvulsant drugs phenytoin, sodium valproate and phenobarbital in the rat.
Topics: Administration, Oral; Animals; Drug Interactions; Enzyme Induction; Liver; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Valproic Acid | 1986 |
Effects of phenobarbital in combination with phenytoin or valproic acid on the delayed-matching-to-sample performance of pigeons.
Topics: Animals; Columbidae; Drug Interactions; Memory, Short-Term; Phenobarbital; Phenytoin; Valproic Acid | 1986 |
Inhibition of quisqualate-induced seizures by glutamic acid diethyl ester and anti-epileptic drugs.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Carbamazepine; Diazepam; Female; Glutamates; Mice; Oxadiazoles; Phenobarbital; Phenytoin; Quisqualic Acid; Seizures; Valproic Acid | 1986 |
Chronic valproic acid and coantiepileptic drug therapy and incidence of increases in serum liver enzymes.
Topics: Adolescent; Adult; Alanine Transaminase; Anticonvulsants; Aspartate Aminotransferases; Child; Child, Preschool; Drug Interactions; Female; Humans; Infant; Liver; Male; Phenobarbital; Phenytoin; Valproic Acid | 1986 |
Anticonvulsant drugs in monotherapy. Effect on the fetus.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fetal Growth Retardation; France; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Italy; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Sweden; Valproic Acid | 1987 |
[Cognitive effects of antiepileptic drugs].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cognition Disorders; Epilepsy; Humans; Memory Disorders; Phenobarbital; Phenytoin; Temporal Lobe; Valproic Acid | 1987 |
Anticonvulsant medication in a mental handicap hospital: 1972-1982.
Topics: Anticonvulsants; Carbamazepine; Female; Hospitals, Psychiatric; Humans; Intellectual Disability; Male; Phenobarbital; Phenytoin; Valproic Acid | 1987 |
Hepatic microsomal enzyme induction: treatment of vitamin D poisoning in a 7 month old baby.
Topics: Enzyme Induction; Humans; Infant; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Vitamin D | 1987 |
Delayed bone development in epileptic children assessed by microdensitometer.
Topics: Adolescent; Anticonvulsants; Bone Development; Calcifediol; Calcitriol; Child; Child, Preschool; Densitometry; Epilepsy; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Radiography; Valproic Acid | 1988 |
Cytochrome P-450-catalyzed desaturation of valproic acid in vitro. Species differences, induction effects, and mechanistic studies.
Topics: Animals; Carbamazepine; Cytochrome P-450 Enzyme System; Deuterium; Enzyme Induction; Fatty Acids, Monounsaturated; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Phenobarbital; Phenytoin; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Valproic Acid | 1988 |
A possible role for spinal noradrenaline in the mechanisms of 6-hydroxydopamine against pentylenetetrazol induced convulsions in rats.
Topics: Animals; Female; Hydroxydopamines; Male; Norepinephrine; Oxidopamine; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Spinal Cord | 1988 |
The role of ultrasound in the early diagnosis of fetal structural defects following maternal anticonvulsant therapy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Diazepam; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Middle Aged; Phenobarbital; Phenytoin; Pregnancy; Prenatal Diagnosis; Prospective Studies; Ultrasonography; Valproic Acid | 1988 |
Pharmacologic interactions between valproate and other drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1988 |
Phenytoin-phenobarbital interaction: importance of free plasma phenytoin monitoring.
Topics: Drug Interactions; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin | 1988 |
Relative efficacy of phenytoin and phenobarbital for the prevention of theophylline-induced seizures in mice.
Topics: Animals; Dose-Response Relationship, Drug; Lethal Dose 50; Male; Mice; Phenobarbital; Phenytoin; Seizures; Theophylline | 1988 |
Simultaneous determination of phenobarbital, phenytoin and methylphenobarbital in tablet formulations by HPLC.
Topics: Chromatography, High Pressure Liquid; Mephobarbital; Phenobarbital; Phenytoin; Tablets | 1988 |
Anticonvulsant hypersensitivity syndrome. In vitro assessment of risk.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross Reactions; Drug Evaluation, Preclinical; Drug Hypersensitivity; Female; Humans; Inactivation, Metabolic; Infant; Lymphocytes; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Phenytoin; Risk | 1988 |
Phenytoin and phenobarbital assayed by the ACCULEVEL method compared with EMIT in an outpatient clinic setting.
Topics: Humans; Immunoassay; Outpatient Clinics, Hospital; Phenobarbital; Phenytoin | 1988 |
Red blood cell uptake of supplemental folate in patients on anticonvulsant drug therapy.
Topics: Adult; Anticonvulsants; Erythrocytes; Folic Acid; Food, Fortified; Humans; Male; Phenobarbital; Phenytoin | 1988 |
Are phenobarbital and phenytoin obsolete in the treatment of epilepsy?
Topics: Epilepsy; Humans; Phenobarbital; Phenytoin | 1988 |
Drug disposition and biotransformation in the developing beagle dog.
Topics: Acetaminophen; Aging; Animals; Biotransformation; Blood Proteins; Dogs; Female; Half-Life; Male; Pharmacokinetics; Phenobarbital; Phenytoin; Protein Binding; Ultrafiltration | 1988 |
Role of human serum biotinidase as biotin-binding protein.
Topics: Amidohydrolases; Binding Sites; Biotin; Biotinidase; Bromosuccinimide; Carbamazepine; Carrier Proteins; Centrifugation, Density Gradient; Chloromercuribenzoates; Chromatography, Gel; Globulins; Humans; Hydrogen-Ion Concentration; p-Chloromercuribenzoic Acid; Phenobarbital; Phenytoin; Serum Albumin | 1988 |
Disposition of phenytoin and phenobarbitone in the isolated perfused human placenta.
Topics: Biotransformation; Carbon Radioisotopes; Female; Humans; Maternal-Fetal Exchange; Perfusion; Phenobarbital; Phenytoin; Placenta; Pregnancy | 1988 |
In vivo evaluation in the lactating rabbit of a model for xenobiotic distribution into breast milk.
Topics: Animals; Diazepam; Female; Hydrogen-Ion Concentration; Lactation; Milk; Models, Biological; Phenobarbital; Phenytoin; Pregnancy; Propranolol; Protein Binding; Rabbits; Xenobiotics | 1988 |
Effects of drugs on aminophylline elimination in rats.
Topics: Aminophylline; Animals; Behavior, Animal; Carbamazepine; Cimetidine; Drug Combinations; Drug Interactions; Erythromycin; Female; Half-Life; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Rifampin; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
Granulomatous lung disease in children by aspiration of medications.
Topics: Administration, Oral; Aminopyrine; Child; Cholestyramine Resin; Female; Foreign-Body Reaction; Granuloma; Humans; Hydroxybenzoates; Infant; Infant, Newborn; Lung; Male; Nitrofurans; Phenobarbital; Phenytoin; Pneumonia, Aspiration | 1987 |
Calibration, quality control, and stability of a quantitative enzyme immunochromatographic method for therapeutic drug monitoring.
Topics: Antibodies, Monoclonal; Calibration; Chromatography, Paper; Immunoenzyme Techniques; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quality Control; Theophylline | 1987 |
Quantitative determination of phenobarbital and phenytoin by dry-phase apoenzyme reactivation immunoassay system (ARIS).
Topics: Apoenzymes; Colorimetry; Evaluation Studies as Topic; Glucose Oxidase; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Photometry; Reagent Strips; Regression Analysis | 1987 |
Barrel rotation in rats induced by intracerebroventricular bradykinin antagonists.
Topics: Animals; Atropine; Bradykinin; Captopril; Diazepam; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraventricular; Male; Motor Activity; Muscimol; Naloxone; Phenobarbital; Phenytoin; Posture; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1987 |
[Methods of monitoring therapeutic agents. I. Use of homogeneous fluorescence immunoanalysis with substrate markers].
Topics: Fluorescent Antibody Technique; Humans; Immunoassay; Phenobarbital; Phenytoin; Theophylline | 1987 |
Effect of pindolol administration on serum levels of thioridazine, haloperidol, phenytoin, and phenobarbital.
Topics: Adult; Aged; Drug Interactions; Drug Therapy, Combination; Haloperidol; Humans; Male; Middle Aged; Neurocognitive Disorders; Phenobarbital; Phenytoin; Pindolol; Rage; Thioridazine; Violence | 1988 |
Effect of anticonvulsants on human chromosomes. 2. In vitro studies.
Topics: Anticonvulsants; Chromosome Aberrations; Chromosomes, Human; Ethosuximide; Humans; In Vitro Techniques; Phenobarbital; Phenytoin | 1988 |
Phenobarbital does not alter phenytoin steady-state serum concentration or pharmacokinetics.
Topics: Adult; Aged; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1988 |
Plasma and urinary taurine in epilepsy.
Topics: Anticonvulsants; Electroencephalography; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Taurine | 1988 |
Episodic nocturnal wanderings in non-epileptic young patients.
Topics: Adult; Brain; Carbamazepine; Electroencephalography; Female; Humans; Male; Monitoring, Physiologic; Phenobarbital; Phenytoin; Somnambulism | 1988 |
Corticosteroid-unresponsive pemphigus vulgaris following antiepileptic therapy.
Topics: Adult; Drug Interactions; Epilepsy; Humans; Male; Pemphigus; Phenobarbital; Phenytoin; Prednisolone; Recurrence | 1988 |
Simultaneous determination of phenytoin and phenobarbital in human serum by electrochemical immunoassay combined with high-performance liquid chromatography.
Topics: Chromatography, Gel; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Immunoassay; Indicators and Reagents; Phenobarbital; Phenytoin | 1988 |
Phenobarbital for status epilepticus.
Topics: Drug Therapy, Combination; Humans; Phenobarbital; Phenytoin; Status Epilepticus | 1988 |
Simultaneous determination of carbamazepine and its epoxide and transdiol metabolites in plasma by microbore liquid chromatography.
Topics: Adult; Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Male; Phenobarbital; Phenytoin; Quality Control; Statistics as Topic; Therapeutic Equivalency | 1988 |
Anticonvulsant effects of a novel aminobenzamide (LY201116) in mice.
Topics: Administration, Oral; Animals; Anticonvulsants; Benzamides; Electroshock; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin | 1988 |
[Studies on dosage of HIDANTOL-F by simultaneous determination of serum phenobarbital and diphenylhydantoin].
Topics: Aged; Drug Combinations; Drug Synergism; Female; Humans; Male; Phenobarbital; Phenytoin; Radioimmunoassay | 1987 |
Fetal anticonvulsant exposure: effects on behavioral and physical development.
Topics: Animals; Anticonvulsants; Female; Humans; Learning; Memory; Motor Activity; Oxazoles; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Reflex, Startle; Trimethadione | 1986 |
Diphenylhydantoin and phenobarbital suppress the dopaminergic neurotoxicity of MPTP in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anticonvulsants; Male; Mice; Mice, Inbred C57BL; Nervous System Diseases; Phenobarbital; Phenytoin; Pyridines; Receptors, Dopamine | 1986 |
[The effect of Hydanphene on reflex activity of the spinal cord].
Topics: Animals; Cats; Drug Combinations; Phenobarbital; Phenytoin; Reflex, Monosynaptic | 1987 |
The effect of hyperlipidemia on therapeutic drug assays.
Topics: Fluorescence Polarization; Gentamicins; Humans; Hyperlipidemias; Immunoenzyme Techniques; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Protein Binding; Triglycerides | 1987 |
Simultaneous measurement of phenobarbital, carbamazepine, phenytoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin in serum by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin | 1987 |
Phenytoin and phenobarbital protein binding alterations in a uremic burn patient.
Topics: Burns; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Seizures; Serum Albumin; Uremia | 1987 |
Minor additive inducing effects of phenobarbital on carbamazepine clearance in patients on combined carbamazepine-phenytoin therapy.
Topics: Aged; Carbamazepine; Drug Interactions; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1987 |
Monitoring of drug therapy in epileptic children.
Topics: Child; Epilepsy; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin | 1987 |
Analysis of serum concentration of phenobarbital, phenytoin, carbamazepine and carbamazepine 10,11-epoxide by solvent-recycled liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin | 1987 |
Evidence of drug metabolism by macrophages: possible role of macrophages in the pathogenesis of drug-induced tissue damage and in the activation of environmental procarcinogens.
Topics: Cells; Cells, Cultured; Chlorpromazine; Cytochrome P-450 Enzyme System; Furans; Humans; Inactivation, Metabolic; Macrophages; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Thymidine | 1987 |
Rapid measurement of anticonvulsant drug concentrations in the out-patient clinic, using HPLC with direct injection of plasma.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin | 1987 |
Effects of anti-convulsants on fatty acid metabolism in human serum.
Topics: Anticonvulsants; Child; Cholesterol; Cholesterol Esters; Fatty Acids; Gas Chromatography-Mass Spectrometry; Humans; Linoleic Acid; Linoleic Acids; Oleic Acid; Oleic Acids; Palmitic Acid; Palmitic Acids; Phenobarbital; Phenytoin; Phosphatidylcholines; Stearic Acids | 1986 |
Spread and arrest of seizures: the importance of layer 4 in laminar interactions during neocortical epileptogenesis.
Topics: Action Potentials; Animals; Anticonvulsants; Bicuculline; Biomechanical Phenomena; Cats; Cerebral Cortex; Disease Susceptibility; Epilepsy; Models, Neurological; Neural Pathways; Neurons; Penicillins; Phenobarbital; Phenytoin; Reaction Time | 1986 |
Phenobarbital improves survival in theophylline-intoxicated rabbits.
Topics: Animals; Injections, Intravenous; Phenobarbital; Phenytoin; Rabbits; Seizures; Theophylline | 1986 |
[The influence on labyrinth behavior of rats of anticonvulsant acting drugs: comparison of propranolol, phenobarbital, phenytoin and diazepam].
Topics: Animals; Anticonvulsants; Behavior, Animal; Diazepam; Male; Phenobarbital; Phenytoin; Propranolol; Rats; Rats, Inbred Strains | 1986 |
Measuring anti-convulsant levels in the accident and emergency department.
Topics: Adult; Carbamazepine; Emergencies; Epilepsy; Humans; Patient Compliance; Phenobarbital; Phenytoin; Prospective Studies | 1986 |
[Phenomenon of "paradoxical poisoning" during antiepileptic therapy].
Topics: Adult; Anticonvulsants; Barbiturates; Carbamazepine; Child; Drug Synergism; Drug Therapy, Combination; Electroencephalography; Epilepsy; Humans; Male; Phenobarbital; Phenytoin | 1986 |
[Concentration of benzonal in the blood of epileptic patients at different daily doses and with other anticonvulsants].
Topics: Adolescent; Adult; Anticonvulsants; Barbiturates; Benzamidines; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin | 1986 |
Antiepileptic drug combinations and experimental background: the case of phenobarbital and phenytoin.
Topics: Animals; Anticonvulsants; Brain Chemistry; Drug Interactions; Female; Mice; Mice, Inbred ICR; Phenobarbital; Phenytoin | 1986 |
Effect of influenza vaccine on serum anticonvulsant concentrations.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Influenza Vaccines; Influenza, Human; Intellectual Disability; Male; Middle Aged; Phenobarbital; Phenytoin; Vaccination | 1986 |
Delayed development of reproductive functions and alteration of dopamine receptor binding in hypothalamus of rats exposed prenatally to phenytoin and phenobarbital.
Topics: Animals; Female; Hypothalamus; Male; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reproduction; Spiperone | 1986 |
[Anticonvulsants in the therapy of glioblastomas].
Topics: Adult; Anticonvulsants; Brain Neoplasms; Carbamazepine; Combined Modality Therapy; Drug Therapy, Combination; Female; Glioma; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prognosis | 1986 |
Effect of anticonvulsant drugs on glutamate neurotoxicity in cortical cell culture.
Topics: Animals; Anticonvulsants; Brain Diseases; Cells, Cultured; Cerebral Cortex; Diazepam; Excitatory Amino Acid Antagonists; Glutamates; Kainic Acid; Mice; Phenobarbital; Phenytoin | 1987 |
[Use of hemodialysis in the treatment of phenobarbitone and phenytoin poisoning].
Topics: Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Renal Dialysis | 1986 |
Dexamethasone bioavailability: implications for DST research.
Topics: Biological Availability; Carbamazepine; Cushing Syndrome; Depressive Disorder; Dexamethasone; Humans; Phenobarbital; Phenytoin; Psychotic Disorders | 1987 |
Toxic hepatopathy and intrahepatic cholestasis associated with phenytoin administration in combination with other anticonvulsant drugs in three dogs.
Topics: Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Dog Diseases; Dogs; Liver Diseases; Male; Phenobarbital; Phenytoin; Primidone; Seizures | 1987 |
Leiomyoblastoma associated with intractable hypercalcemia and elevated 1,25-dihydroxycholecalciferol levels. Treatment by hepatic enzyme induction.
Topics: Adult; Calcitriol; Enzyme Induction; Female; Humans; Hypercalcemia; Leiomyoma; Liver; Liver Neoplasms; Phenobarbital; Phenytoin | 1985 |
Multiple cerebral defects in an infant exposed in utero to anticonvulsants.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anticonvulsants; Brain; Cerebral Ventricles; Encephalocele; Female; Humans; Infant, Newborn; Phenobarbital; Phenytoin | 1985 |
Studies of qingyangshen (root of Cynanchum otophyllum). I. Effect of qingyangshen on copper and zinc metabolism.
Topics: Animals; Anticonvulsants; Copper; Drugs, Chinese Herbal; Epilepsy; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Mice; Phenobarbital; Phenytoin; Plant Extracts; Plants, Medicinal; Zinc | 1985 |
Effect of chronic anticonvulsant monotherapy on lymphocyte subpopulations in adult epileptic patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Complement System Proteins; Epilepsy; Female; Humans; Immunoglobulins; Leukocyte Count; Lymphocytes; Male; Middle Aged; Phenobarbital; Phenytoin; T-Lymphocytes | 1985 |
Evaluation of an automated system (Optimate) for substrate-labeled fluorescent immunoassays.
Topics: Anti-Bacterial Agents; Carbamazepine; Evaluation Studies as Topic; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Indicators and Reagents; Methods; Phenobarbital; Phenytoin; Primidone; Quinidine; Theophylline | 1985 |
Effects of pregnancy on seizure threshold and the disposition and efficacy of antiepileptic drugs in the mouse.
Topics: Animals; Anticonvulsants; Carbamazepine; Electroshock; Female; Kinetics; Mice; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Seizures; Time Factors; Valproic Acid | 1985 |
Postictal pulmonary edema in children.
Topics: Carbamazepine; Child; Epilepsies, Partial; Furosemide; Humans; Intubation, Intratracheal; Male; Oxygen; Patient Compliance; Phenobarbital; Phenytoin; Positive-Pressure Respiration; Pulmonary Edema; Respiration, Artificial | 1985 |
Effects of phenytoin, phenobarbital, and valproic acid, alone and in selected combinations, on schedule-controlled behavior of rats.
Topics: Animals; Conditioning, Operant; Drug Interactions; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Reinforcement Schedule; Time Factors; Valproic Acid | 1985 |
Antiepileptic drug evaluation in a new animal model: spontaneous petit mal epilepsy in the rat.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Ethosuximide; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Trimethadione; Valproic Acid | 1985 |
Effects of pregnancy on antiepileptic drug utilization.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Epilepsy; Female; Humans; Kinetics; Metabolic Clearance Rate; Patient Compliance; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Valproic Acid | 1985 |
Anticonvulsant drugs and the genetically epilepsy-prone rat.
Topics: Acoustic Stimulation; Amitriptyline; Animals; Anticonvulsants; Carbamazepine; Desipramine; Disease Models, Animal; Epilepsy; Ethosuximide; Imipramine; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1985 |
Concurrent determination of valproic acid with other antiepileptic drugs by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1985 |
Effect of associated antiepileptic treatment on valproate-induced hyperammonemia.
Topics: Adolescent; Adult; Ammonia; Anticonvulsants; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Time Factors; Valproic Acid | 1985 |
Ligand displacement immunoassay--demonstration of its use for the measurement of serum phenobarbital and phenytoin.
Topics: beta-Galactosidase; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1985 |
Monotherapy and polytherapy for intractable epilepsies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1985 |
Effects of phenobarbital, clonazepam, valproic acid, ethosuximide, and phenytoin on the delayed matching-to-sample performance of pigeons.
Topics: Animals; Anticonvulsants; Clonazepam; Columbidae; Conditioning, Psychological; Dose-Response Relationship, Drug; Ethosuximide; Memory; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
Interictal EEG prediction of response to antiepileptic drug monotherapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prognosis; Sleep Deprivation; Valproic Acid | 1985 |
American Academy of Pediatrics. Behavioral and cognitive effects of anticonvulsant therapy. Committee on Drugs.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Child; Child Behavior Disorders; Clonazepam; Cognition; Humans; Infant; Memory Disorders; Phenobarbital; Phenytoin; Psychological Tests; Valproic Acid | 1985 |
Convulsive thresholds and severity and the anticonvulsant effect of phenobarbital and phenytoin in adult rats administered 6-hydroxydopamine or 5,7-dihydroxytryptamine during postnatal development.
Topics: 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Anticonvulsants; Biogenic Amines; Dihydroxytryptamines; Electroshock; Female; Hydroxydopamines; Oxidopamine; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures | 1985 |
Chronic valproic acid therapy and incidence of increases in venous plasma ammonia.
Topics: Adolescent; Adult; Aged; Ammonia; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
The optimum use of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
Where, why, and what type of therapy.
Topics: Carbamazepine; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Recurrence; Risk; Succinimides; Valproic Acid | 1985 |
Monitoring: the most important role of the pediatrician.
Topics: Activities of Daily Living; Anticonvulsants; Carbamazepine; Child, Preschool; Environmental Monitoring; Epilepsy; Ethosuximide; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Referral and Consultation; Social Support; Valproic Acid | 1985 |
Serum concentrations of valproic acid: influence of dose and comedication.
Topics: Adolescent; Adult; Body Weight; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Valproic Acid | 1985 |
Seizure control following administration of anticonvulsant drugs in the quaking mouse.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Ethosuximide; Mice; Mice, Inbred C57BL; Mice, Quaking; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1985 |
Use of total and free anticonvulsant serum levels in clinical practice.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
Alternative single anticonvulsant drug therapy for refractory epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Chronic Disease; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1986 |
The influence of seizure type on the efficacy of plasma concentrations of phenytoin, phenobarbital, and carbamazepine.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1986 |
Ovarian hormones, anticonvulsant drugs, and seizures during the menstrual cycle in women with epilepsy.
Topics: Adolescent; Adult; Epilepsy; Estradiol; Estriol; Estrone; Female; Gonadal Steroid Hormones; Humans; Menstrual Cycle; Phenobarbital; Phenytoin; Progesterone | 1986 |
Carbamazepine and carbamazepine-10,11-epoxide serum concentrations in epileptic children.
Topics: Adolescent; Age Factors; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Kinetics; Male; Phenobarbital; Phenytoin; Primidone; Sex Factors | 1985 |
Effects of anesthetic and anticonvulsant drugs on calcium-dependent efflux of potassium from human erythrocytes.
Topics: Anesthetics; Anticonvulsants; Calcium; Erythrocytes; Humans; In Vitro Techniques; Phenobarbital; Phenytoin; Potassium; Radioisotopes; Rubidium | 1985 |
Interpreting drug levels.
Topics: Carbamazepine; Digoxin; Phenobarbital; Phenytoin; Theophylline | 1985 |
Anticonvulsant use during pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Epilepsy; Female; Fetal Death; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Risk; Trimethadione | 1985 |
Status epilepticus.
Topics: Adult; Aged; Anticonvulsants; Diazepam; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Status Epilepticus; Time Factors | 1985 |
Modification of the antiepileptic actions of phenobarbital and phenytoin by the taurine transport inhibitor, guanidinoethane sulfonate.
Topics: Amino Acids; Animals; Anticonvulsants; Brain; Electroshock; Male; Mice; Phenobarbital; Phenytoin; Seizures; Taurine | 1985 |
Steady-state serum levels of anticonvulsant drugs in Chinese epileptic patients living in Taiwan.
Topics: Adolescent; Adult; Age Factors; Asian People; Body Weight; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Taiwan | 1985 |
Epilepsy in a community--management and social impact.
Topics: Adolescent; Adult; Aged; Ambulatory Care Facilities; Carbamazepine; Craniocerebral Trauma; Epilepsy; Female; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Seizures; Socioeconomic Factors; Stress, Physiological | 1985 |
Effect of antiepileptic drugs on short-latency somatosensory evoked potentials.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Evoked Potentials, Somatosensory; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Reaction Time | 1985 |
Practical problems of therapeutic drug monitoring of anticonvulsants.
Topics: Adolescent; Adult; Anticonvulsants; Blood Specimen Collection; Child; Humans; Kinetics; Monitoring, Physiologic; Phenobarbital; Phenytoin; Seizures; Time Factors | 1985 |
Efficacy of phenobarbital in neonatal seizures.
Topics: Humans; Infant, Newborn; Phenobarbital; Phenytoin; Retrospective Studies; Seizures | 1985 |
Comparison of equilibrium dialysis, ultrafiltration, and gel permeation chromatography for the determination of free fractions of phenobarbital and phenytoin.
Topics: Chromatography, Gel; Dialysis; Humans; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Ultrafiltration | 1985 |
Use of serum drug concentrations in outpatient clinics.
Topics: Carbamazepine; Digoxin; Humans; Medication Systems, Hospital; Outpatient Clinics, Hospital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Procainamide; Quinidine; Theophylline; Wisconsin | 1985 |
Disregulation of hypothalamic-pituitary-adrenal axis in the mentally retarded.
Topics: Adult; Depressive Disorder; Dexamethasone; Hospitalization; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Intellectual Disability; Phenobarbital; Phenytoin; Pituitary-Adrenal System | 1985 |
[Dissolution processes and surface alteration. 4. Determination of the "effective" surface].
Topics: Diffusion; Kinetics; Models, Chemical; Phenobarbital; Phenytoin; Salicylates; Salicylic Acid; Solubility; Surface Properties | 1985 |
Reduced taurine contents and modification of anticonvulsive effects of phenobarbital and phenytoin by guanidinoethane sulfonate in mice.
Topics: Amino Acids; Animals; Anticonvulsants; Brain; Male; Phenobarbital; Phenytoin; Rats; Seizures; Taurine | 1985 |
[Anticonvulsive prophylaxis after juvenile craniocerebral injuries: a retrospective evaluation].
Topics: Anticonvulsants; Brain Concussion; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Follow-Up Studies; Humans; Phenobarbital; Phenytoin; Time Factors; Unconsciousness | 1985 |
Intracranial hemorrhage in children with sickle cell disease.
Topics: Anemia, Sickle Cell; Arteries; Brain; Cerebral Infarction; Child; Child, Preschool; Exchange Transfusion, Whole Blood; Female; Humans; Male; Phenobarbital; Phenytoin; Seizures; Subarachnoid Hemorrhage | 1985 |
Gastrointestinal dialysis with activated charcoal and cathartic in the treatment of adolescent intoxications.
Topics: Adolescent; Adsorption; Adult; Aspirin; Cathartics; Charcoal; Female; Gastric Lavage; Half-Life; Humans; Intestinal Absorption; Male; Phenobarbital; Phenytoin; Poisoning | 1985 |
Serum low-density lipoprotein and high-density lipoprotein cholesterol, and liver size in subjects on drugs inducing hepatic microsomal enzymes.
Topics: Adult; Carbamazepine; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Humans; Liver; Male; Microsomes, Liver; Middle Aged; Organ Size; Phenobarbital; Phenytoin; Risk | 1985 |
[Drug interactions in the use of steroid hormones, especially oral contraceptives].
Topics: Biotransformation; Contraceptives, Oral, Hormonal; Cytochrome P-450 CYP1A1; Drug Interactions; Female; Humans; Hydroxylation; Liver; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Rifampin; Steroid Hydroxylases | 1985 |
Case report: psychosis with Stevens-Johnson syndrome and toxic epidermal necrolysis.
Topics: Adult; Basal Ganglia; Female; Humans; Phenobarbital; Phenytoin; Psychotic Disorders; Stevens-Johnson Syndrome | 1985 |
Status epilepticus in pregnancy. A case report.
Topics: Adolescent; Diazepam; Female; Humans; Infusions, Parenteral; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Status Epilepticus | 1985 |
Status epilepticus.
Topics: Anesthesia, General; Child; Diazepam; Humans; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus; Time Factors | 1985 |
The role of antiepileptics in sudden death in epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Death, Sudden; Epilepsy; Female; Humans; Male; Patient Compliance; Phenobarbital; Phenytoin | 1985 |
Results of spin immunoassay for simultaneous measurement of phenytoin and phenobarbital in serum compared with those of liquid chromatography.
Topics: Animals; Chromatography, Liquid; Immunoassay; Male; Phenobarbital; Phenytoin; Rabbits | 1985 |
[Convulsive crises in childhood].
Topics: Clonazepam; Crying; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Infant; Infant, Newborn; Migraine Disorders; Phenobarbital; Phenytoin; Respiratory Insufficiency; Seizures; Seizures, Febrile; Syncope; Vertigo | 1985 |
Plasma gamma-glutamyl transpeptidase elevation in patients receiving enzyme-inducing drugs.
Topics: Acyltransferases; Depression; Drug Synergism; Enzyme Induction; Epilepsy; Ethanol; Glutamates; Humans; Liver; Liver Function Tests; Microsomes, Liver; Phenobarbital; Phenytoin; Postoperative Complications; Skull | 1971 |
Phenobarbitone increases rat-liver gamma-glutamyl transpeptidase.
Topics: Acyltransferases; Animals; Enzyme Induction; Ethanol; Glutamates; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1971 |
[Clinical study on determination of blood thyroid hormone levels using the protein binding test--free thyroxine index in young children].
Topics: Age Factors; Androgens; Antithyroid Agents; Child; Child, Preschool; Down Syndrome; Dwarfism, Pituitary; Estrogens; Female; Goiter; Humans; Hyperthyroidism; Hypothyroidism; Infant; Iodine; Male; Nephrotic Syndrome; Obesity; Penicillins; Phenobarbital; Phenytoin; Thyroid Function Tests; Thyroiditis; Thyroxine; Umbilical Arteries | 1971 |
Congenital malformations among infants born to epileptic women.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Congenital Abnormalities; England; Epilepsy; Female; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone | 1973 |
Ultraviolet spectrophotometric analysis of barbiturates: evaluation of potential interferences.
Topics: Acetaminophen; Barbiturates; Chlorothiazide; Chlorpropamide; Dicumarol; Humans; Methods; Nicotinic Acids; Oxyphenbutazone; Phenacetin; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Salicylates; Spectrophotometry, Ultraviolet; Sulfamethoxazole; Sulfinpyrazone; Sulfisoxazole; Theobromine; Theophylline; Warfarin | 1973 |
4 C-sex vertex spindles.
Topics: Action Potentials; Brain; Brain Concussion; Cerebrovascular Disorders; Electroencephalography; Epilepsy; Eye Movements; Humans; Hyperventilation; Mental Disorders; Migraine Disorders; Motor Activity; Phenobarbital; Phenytoin; Sleep | 1973 |
[Control of long-term therapy with diphenylhydantoin. Gas-chromatographic determination of diphenylhydantoin and hydroxy-diphenylhydantoin].
Topics: Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Seizures; Time Factors | 1973 |
Coarse features in epilepsy as a consequence of anticonvulsant therapy. Report of cases in two pairs of identical twins.
Topics: Acromegaly; Adult; Anticonvulsants; Carbamazepine; Child; Diazepam; Diseases in Twins; Epilepsy; Epilepsy, Tonic-Clonic; Ethosuximide; Face; Female; Haloperidol; Humans; Hydantoins; Male; Phenobarbital; Phenytoin; Primidone; Thiazines | 1973 |
Cutis aplasia and cerebral malformation.
Topics: Cephalometry; Cerebrospinal Fluid Proteins; Developmental Disabilities; Female; Humans; Hydranencephaly; Infant, Newborn; Intracranial Pressure; Knee; Phenobarbital; Phenytoin; Radiography; Reflex, Abnormal; Scalp Dermatoses; Seizures; Skin Diseases; Transillumination | 1973 |
Are anticonvulsants oncogenic?
Topics: Anticonvulsants; Denmark; Epilepsy; Female; Humans; Male; Neoplasms; Phenobarbital; Phenytoin; Primidone; Sex Factors; Time Factors | 1974 |
Protection by catatoxic steroids against the paralysis caused by combined treatment with thyroxine and methylphenidate.
Topics: Androstenols; Animals; Drug Synergism; Estradiol; Ethylestrenol; Female; Humans; Hydroxysteroids; Hyperkinesis; Ketosteroids; Methylphenidate; Norpregnanes; Paralysis; Phenobarbital; Phenytoin; Prednisolone; Pregnenolone Carbonitrile; Progesterone; Propionates; Rats; Rats, Inbred Strains; Spironolactone; Steroids; Thyroxine | 1972 |
Letter: Treatment of hiccup.
Topics: Adolescent; Adult; Carbamazepine; Diazepam; Drug Therapy, Combination; Female; Hiccup; Humans; Male; Phenobarbital; Phenytoin | 1974 |
[Calcium metabolism during antiepileptic therapy].
Topics: Adult; Alkaline Phosphatase; Anticonvulsants; Antipsychotic Agents; Calcium; Calcium Isotopes; Creatinine; Diazepam; Drug Combinations; Epilepsy; Ethosuximide; Female; Humans; Long-Term Care; Male; Phenobarbital; Phenothiazines; Phenytoin; Piperazines; Primidone; Time Factors | 1973 |
The protection against the cerebral and pulmonary effects of hyperbaric oxygen by pharmacological agents and lithium salts in mice.
Topics: Acetates; Aminobutyrates; Animals; Anticonvulsants; Antipsychotic Agents; Brain; Chlorpromazine; Female; Hydroxybutyrates; Hyperbaric Oxygenation; Lithium; Lung; Mice; Oxazoles; Phenobarbital; Phenytoin; Prochlorperazine; Promazine; Pulmonary Edema; Seizures; Water | 1973 |
Comparative convulsant activity of various penicillins after intracerebral injection in mice.
Topics: Ampicillin; Animals; Cephaloridine; Drug Synergism; Hydrogen-Ion Concentration; Injections; Male; Methicillin; Mice; Penicillin G; Penicillin V; Penicillinase; Penicillins; Pentylenetetrazole; Phenobarbital; Phenytoin; Potassium; Seizures; Sodium | 1973 |
Myopathy associated with anticonvulsant osteomalacia.
Topics: Adult; Anticonvulsants; Back Pain; Depression; Electroencephalography; Electromyography; Ergocalciferols; Female; Folic Acid; Hemoglobins; Humans; Intelligence; Microscopy, Electron; Muscular Diseases; Osteomalacia; Paralysis; Phenobarbital; Phenytoin; Thiazines; Vitamin D | 1973 |
The effect of certain drugs on the plasma protein binding of phenytoin.
Topics: Anticonvulsants; Aspirin; Binding Sites; Blood Proteins; Carbamazepine; Dialysis; Diazepam; Ethosuximide; Humans; In Vitro Techniques; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Temperature; Thiazines; Ultrafiltration | 1973 |
Specific H-bonding of glutarimides and hydantoins to derivatives of RNA bases in chloroform solution.
Topics: Bemegride; Chemical Phenomena; Chemistry; Chloroform; Cycloheximide; Ethosuximide; Glutethimide; Hydantoins; Pemoline; Phenobarbital; Phenytoin; Piperidines; Piperidones; Primidone; RNA; Spectrophotometry, Infrared; Thalidomide | 1973 |
Inhibition of bovine brain aldehyde reductase by anticonvulsant compounds in vitro.
Topics: Aldehyde Oxidoreductases; Amobarbital; Animals; Anticonvulsants; Barbiturates; Brain; Cattle; Ethosuximide; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isomerism; Kinetics; Mephobarbital; NADP; Pentobarbital; Phenobarbital; Phenytoin; Spectrometry, Fluorescence; Spectrophotometry; Succinimides; Trimethadione | 1973 |
Anticonvulsant testing with a new analeptic convulsant: N-sulfamoyl-hexahydro-azepine (Sah 41-178).
Topics: Acetamides; Animals; Anticonvulsants; Azepines; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Glutethimide; Haloperidol; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Strychnine; Sulfonamides; Trimethadione | 1973 |
Interference in the Zimmerman test for steroids.
Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; 17-Ketosteroids; Carbamazepine; Evaluation Studies as Topic; Humans; Methods; Nitrazepam; Phenobarbital; Phenytoin; Spectrometry, Fluorescence; Spectrophotometry; Thiazines | 1974 |
Relationship of serum triglyceride lowering to changes in hepatic composition induced by different classes of drugs.
Topics: Animals; Cholesterol; Clofibrate; Dactinomycin; DNA; Dose-Response Relationship, Drug; Glycolates; Hepatomegaly; Hypolipidemic Agents; In Vitro Techniques; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Nafenopin; Oxidoreductases, N-Demethylating; Phenobarbital; Phenyl Ethers; Phenytoin; Phospholipids; Piperazines; Piperidines; Propionates; Proteins; Rats; RNA; Spectrophotometry, Ultraviolet; Triglycerides | 1974 |
Choreo-athetosis and encephalopathy induced by phenytoin.
Topics: Adolescent; Adult; Ataxia; Athetosis; Carbamazepine; Chorea; Diplopia; Electroencephalography; Epilepsy; Humans; Intelligence; Male; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Thiazines | 1974 |
Prevalence and treatment of vitamin D deficiency in children on anticonvulsant drugs.
Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Calcium; Cholecalciferol; Diet; Enzyme Induction; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Leucyl Aminopeptidase; Liver; Male; Nucleotidases; Phenobarbital; Phenytoin; Phosphates; Primidone; Radiography; Vitamin D Deficiency; Wrist | 1974 |
A comparison between the personality changes in certain forms of psychomotor and grand-mal epilepsy.
Topics: Adult; Depression; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Male; MMPI; Personality Disorders; Phenobarbital; Phenytoin; Suicide; Vertigo | 1974 |
Potentiation of drug-initiated adrenal tyrosine hydroxylase induction by diazepam.
Topics: Adrenal Glands; Animals; Biogenic Amines; Blood-Brain Barrier; Diazepam; Drug Synergism; Enzyme Induction; Hydroxydopamines; Insulin; Isoproterenol; Male; Neurons; Pentobarbital; Phenobarbital; Phenytoin; Rats; Reserpine; Serotonin; Tyrosine 3-Monooxygenase | 1974 |
Vertigo in childhood. Comments on pathogenesis and management.
Topics: Adolescent; Anticonvulsants; Central Nervous System; Child; Dimenhydrinate; Female; Histamine H1 Antagonists; Humans; Male; Meningitis; Phenobarbital; Phenytoin; Seizures; Sinusitis; Vertigo; Vestibular Nerve; Vestibule, Labyrinth; Wounds and Injuries | 1974 |
Assessment of plasma glutamyl transpeptidase activity and urinary D-glucaric acid excretion as indices of enzyme induction.
Topics: Adipates; Anticonvulsants; Child; Child, Preschool; Enzyme Induction; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Kinetics; Liver Function Tests; Male; Phenobarbital; Phenytoin; Primidone; Sugar Acids | 1974 |
Epilepsy.
Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant, Newborn; Liver; Nitrazepam; Phenobarbital; Phenytoin; Prednisolone; Primidone; Spasm; Syndrome; Thiazines | 1974 |
Gastrointestinal function in anticonvulsant megaloblastic anaemia.
Topics: Adult; Anemia, Macrocytic; Epilepsy; Female; Folic Acid; Humans; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1966 |
Dicoumarol-induced diphenylhydantoin intoxication.
Topics: Blood; Carbon Isotopes; Chromatography, Thin Layer; Dicumarol; Drug Synergism; Humans; Phenobarbital; Phenytoin | 1966 |
Effects of folic acid on the mental state and fit-frequency of drug-treated epileptic patients.
Topics: Adolescent; Adult; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Humans; Male; Mental Health; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1967 |
Death?
Topics: Humans; Infant; Infant Mortality; Myoclonus; Phenobarbital; Phenytoin | 1967 |
Dose-dependence of drug plasma level decline in dogs.
Topics: Acetates; Animals; Barbiturates; Blood Proteins; Chlorine; Chromatography, Thin Layer; Dicumarol; Dogs; Kinetics; Liver; Muscles; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Probenecid; Receptors, Drug; Vitamin K | 1967 |
Neuropsychiatric aspects of anticonvulsant megaloblastic anaemia.
Topics: Acetazolamide; Adult; Anemia, Macrocytic; Epilepsy; Female; Folic Acid; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Psychophysiologic Disorders; Thiazines; Vitamin B 12 | 1968 |
Longitudinal EEG and clinical study of children with febrile convulsions.
Topics: Acute Disease; Age Factors; Blood Chemical Analysis; Cerebral Cortex; Child, Preschool; Electroencephalography; Epilepsy; Evoked Potentials; Fever; Follow-Up Studies; Humans; Infant; Light; Male; Occipital Lobe; Phenobarbital; Phenytoin; Seizures | 1968 |
Reaction of drugs with microsomal liver hydroxylase: its influence on drug action.
Topics: Aniline Compounds; Animals; Antipyrine; Benzopyrenes; Cytochromes; Dicumarol; Electron Transport; Enzyme Induction; Hexobarbital; Kinetics; Liver; Methylcholanthrene; Microsomes; Mixed Function Oxygenases; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Protein Binding; Prothrombin Time | 1968 |
Effect of anticonvulsant drugs on dicophane (D.D.T.) residues in man.
Topics: Adipose Tissue; Child; Chromatography, Gas; DDT; Humans; Phenobarbital; Phenytoin | 1969 |
Neonatal haemorrhage following maternal anticonvulsant therapy.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Vitamin K; Vitamin K Deficiency Bleeding | 1970 |
Effect of anticonvulsant drugs on insecticide residues.
Topics: Agriculture; Epilepsy; Humans; Insecticides; Phenobarbital; Phenytoin | 1970 |
[Distinct rickets during anticonvulsant long-term therapy].
Topics: Child, Preschool; Enzyme Induction; Epilepsy, Tonic-Clonic; Female; Humans; Phenobarbital; Phenytoin; Primidone; Radiography; Rickets; Vitamin D | 1973 |
The effect of anticonvulsant therapy upon the absorption of folates.
Topics: Adult; Aged; Anticonvulsants; Biological Assay; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Absorption; Lacticaseibacillus casei; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1973 |
Anticonvulsant drugs in human epileptogenic brain. Correlation of phenobarbital and diphenylhydantoin levels with plasma.
Topics: Adolescent; Adult; Aged; Animals; Biopsy; Cerebral Cortex; Child; Electroencephalography; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Humans; Male; Median Nerve; Middle Aged; Phenobarbital; Phenytoin; Rats; Sciatic Nerve; Spinal Cord | 1973 |
Infantile hemiplegic disorder.
Topics: Child, Preschool; Epilepsy, Tonic-Clonic; Hemiplegia; Humans; Infant; Male; Phenobarbital; Phenytoin | 1973 |
[Inheritance of spike-wave complexes and febrile seizures in three generations].
Topics: Adult; Child; Child, Preschool; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Fever; Genes, Dominant; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Time Factors | 1973 |
Antiepileptic therapy and rickets in children.
Topics: Adolescent; Anticonvulsants; Barbiturates; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Male; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Rickets | 1973 |
The pattern of epilepsy in Uganda.
Topics: Adolescent; Adult; Age Factors; Black People; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Folklore; Humans; Male; Phenobarbital; Phenytoin; Primidone; Sex Factors; Socioeconomic Factors; Time Factors; Uganda | 1973 |
Folate studies in underprivileged children with epilepsy.
Topics: Anticonvulsants; Biological Assay; Child; Child, Preschool; Epilepsy; Euglena; Folic Acid; Hematocrit; Hemoglobins; Humans; Lacticaseibacillus casei; Leukocyte Count; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1973 |
Digital hypoplasia and anticonvulsants during gestation: a teratogenic syndrome?
Topics: Abnormalities, Drug-Induced; Epilepsy, Tonic-Clonic; Female; Fingers; Hand; Humans; Infant, Newborn; Nails, Malformed; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Radiography | 1974 |
[Worsening of epilepsies under treatment].
Topics: Anticonvulsants; Benzodiazepinones; Child; Child, Preschool; Chlorobenzenes; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Evaluation Studies as Topic; Female; Humans; Male; Nitro Compounds; Phenobarbital; Phenytoin | 1973 |
Psychomotor epilepsy in childhood.
Topics: Bromides; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Infant; Phenobarbital; Phenytoin; Primidone; Radiography; Recurrence; Skull; Time Factors | 1974 |
Epilepsy in cerebral hydatidosis.
Topics: Adolescent; Adult; Brain Diseases; Child; Child, Preschool; Dominance, Cerebral; Echinococcosis; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Male; Paralysis; Paresthesia; Perceptual Disorders; Phenobarbital; Phenytoin; Postoperative Complications; Recurrence; Speech Disorders; Stereognosis | 1974 |
Congestive heart failure secondary to idiopathic hypoparathyroidism.
Topics: Adolescent; Calcium; Diagnostic Errors; Digoxin; Electrocardiography; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Furosemide; Gluconates; Heart; Heart Failure; Humans; Hypocalcemia; Hypoparathyroidism; Oxygen Inhalation Therapy; Phenobarbital; Phenytoin; Phosphorus; Radiography; Vitamin D | 1974 |
Bilateral symmetrical periarticular trauma in epileptics.
Topics: Adult; Epilepsy, Tonic-Clonic; Femoral Fractures; Fracture Fixation, Internal; Humans; Joints; Male; Middle Aged; Phenobarbital; Phenytoin; Radiography; Shoulder Dislocation | 1974 |
Diphenylhydantoin--induced hepatic necrosis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Epilepsy, Tonic-Clonic; Female; Fever; Humans; Liver; Liver Diseases; Lymph Nodes; Necrosis; Phenobarbital; Phenytoin; Prednisone; Rubella; Skin Diseases; Toxemia | 1974 |
Occipital lobe epilepsy. A clinical and electroencephalographic study.
Topics: Adolescent; Adult; Blindness; Child; Diagnosis, Differential; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Male; Migraine Disorders; Occipital Lobe; Oculomotor Nerve; Phenobarbital; Phenytoin; Recurrence | 1974 |
Letter: Treatment of status epilepticus with sodium valproate.
Topics: Adolescent; Anticonvulsants; Diazepam; Epilepsy, Tonic-Clonic; Female; Humans; Phenobarbital; Phenytoin; Valerates | 1974 |
Therapy of seizures in children.
Topics: Child; Diazepam; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Injections, Intramuscular; Injections, Intravenous; Paraldehyde; Phenobarbital; Phenytoin; Primidone; Rectum; Seizures | 1974 |
The effects of diphenylhydantoin, phenobarbital, and diazepam on the penicillin-induced epileptogenic focus in the rat.
Topics: Animals; Autoradiography; Brain; Carbon Radioisotopes; Diazepam; Disease Models, Animal; Electroencephalography; Epilepsies, Partial; Male; Penicillin G; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Scintillation Counting; Seizures | 1974 |
Paroxysmal kinesignenic choreoathetosis. Report of a case relieved by carbamazepine.
Topics: Adolescent; Athetosis; Carbamazepine; Diazepam; Dibenzazepines; Diphenhydramine; Female; Humans; Huntington Disease; Lactose; Phenobarbital; Phenytoin | 1969 |
Discharging cortical lesions produced by freezing. The effect of anticonvulsants on sodium-potassium-activated ATPase, sodium, and potassim in cortex.
Topics: Adenosine Triphosphatases; Animals; Anticonvulsants; Cerebral Cortex; Enzyme Repression; Female; Freezing; Injections, Intraperitoneal; Phenobarbital; Phenytoin; Potassium; Rats; Seizures; Sodium | 1969 |
[Differences between the protein binding of newborns and adults and their importance for pharmacological action].
Topics: Acetaminophen; Age Factors; Aminosalicylic Acids; Atropine; Chloramphenicol; Humans; Infant, Newborn; Isoniazid; Methicillin; Morphine; Nitrofurantoin; Oxyphenbutazone; Phenacetin; Phenobarbital; Phenytoin; Promethazine; Protein Binding; Salicylates; Sulfadimethoxine; Thiopental | 1968 |
[Effect of phenobarbital and diphenylhydantoin on different lipid fractions of liver].
Topics: Animals; Choline Deficiency; Ethanol; Fatty Liver; Liver; Phenobarbital; Phenytoin; Phospholipids; Rats; Triglycerides | 1968 |
Studies on the mechanism of action of diphenylhydantoin.
Topics: Adenosine Triphosphatases; Animals; Biological Transport; Crustacea; Cyanides; Hypoxia; Neurons; Ouabain; Peripheral Nerves; Phenobarbital; Phenytoin; Potassium; Schwann Cells; Sodium; Tetrodotoxin; Trimethadione | 1970 |
On the relationship migraine--epilepsy.
Topics: Anticonvulsants; Electroencephalography; Epilepsy, Temporal Lobe; Humans; Migraine Disorders; Phenobarbital; Phenytoin | 1971 |
[Effect of various drugs on lipid content and drug metabolizing enzymes in rat liver following experimentally induced fatty degeneration].
Topics: Animals; Choline Deficiency; Enzyme Induction; Fatty Liver; Lipid Metabolism; Liver; Male; Microsomes, Liver; Naphthalenes; Phenobarbital; Phenols; Phenytoin; Propionates; Rats | 1970 |
An adult form of acanthocytosis.
Topics: Abetalipoproteinemia; Adult; Ataxia; Diazepam; Female; Haloperidol; Humans; Huntington Disease; Hydroxyzine; Male; Phenobarbital; Phenytoin; Trihexyphenidyl | 1967 |
Radiologic bone changes and hypocalcemia with anticonvulsant therapy in epilepsy.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Anticonvulsants; Back Pain; Calcium; Carbamazepine; Diarrhea; Epilepsy; Female; Femur; Fractures, Bone; Humans; Hypocalcemia; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Radiography | 1972 |
Clinical and experimental studies on folic acid deficiency due to anticonvulsants. I. Clinical and nutritional study on megalobastic anemia due to anticonvulsants.
Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Diet; Epilepsy, Temporal Lobe; Folic Acid; Folic Acid Deficiency; Food Analysis; Humans; Male; Phenobarbital; Phenytoin | 1971 |
Clinical and experimental studies on folic acid deficiency due to anticonvulsants. 2. Investigations on patients receiving anticonvulsants and experimental study on the effect of diphenylhydantoin on the absorption of folic acid in rats.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Cell Nucleus; Depression, Chemical; Epithelial Cells; Female; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Absorption; Intestine, Small; Iron; Kidney; Leukocyte Count; Liver; Male; Middle Aged; Mouth Mucosa; Neutrophils; Phenobarbital; Phenytoin; Primidone; Rats; Tritium; Vitamin B 12 | 1971 |
Paroxysmal choreoathetosis. Report of Chinese cases.
Topics: Adult; Age Factors; Athetosis; China; Electroencephalography; Epilepsy; Female; Humans; Huntington Disease; Male; Pedigree; Phenobarbital; Phenytoin; Sex Factors; Taiwan | 1973 |
The action of antiepileptic drugs--diphenylhydantoin and phenobarbital--on enzymatic systems involved in the active transport of cations. Study of ATP-ase activity in various brain regions and the erythrocyte of the cat.
Topics: Adenosine Triphosphatases; Animals; Brain; Cats; Erythrocytes; Phenobarbital; Phenytoin; Potassium; Seizures; Sodium | 1973 |
Calcium ATPase activity in drug-induced osteomalacia.
Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Anticonvulsants; Calcium; Erythrocytes; Humans; Magnesium; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Sodium | 1973 |
Failure of metyrapone to inhibit 11-hydroxylation of 11-deoxycortisol during drug therapy.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Chromatography, Paper; Chromatography, Thin Layer; Cushing Syndrome; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Metyrapone; Phenobarbital; Phenytoin; Pituitary Function Tests; Secretory Rate; Steroids | 1967 |
Biochemical changes in rat liver in response to treatment with drugs and other agents. I. Effects of anticonvulsant, anti-inflammatory, hypocholesterolaemic and adrenergic beta-blocking agents.
Topics: Acetanilides; Aminopyrine; Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Anticonvulsants; Barbiturates; Body Weight; Butyrates; Cytochromes; Cytoplasm; Electron Transport; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Indomethacin; L-Lactate Dehydrogenase; Liver; Male; Microsomes; Organ Size; Oxidoreductases; Phenobarbital; Phenylbutazone; Phenytoin; Phosphogluconate Dehydrogenase; Propranolol; Proteins; Rats; Sympatholytics | 1969 |
A particular pharmacological effect on the propagation of experimental strychnine and penicillin epilepsy.
Topics: Acetates; Animals; Anticonvulsants; Cerebral Cortex; Chlorpromazine; Electroencephalography; Electroshock; Female; Male; Penicillins; Pentobarbital; Phenobarbital; Phenytoin; Rabbits; Seizures; Sound; Strychnine; Synaptic Transmission | 1969 |
Dilantin and metyrapone: a clinically significant example of enzyme induction.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Animals; Depression, Chemical; Endoplasmic Reticulum; Enzyme Induction; Epilepsy; Estrogens; Glucuronates; Humans; Hyperplasia; Hypopituitarism; Liver; Metyrapone; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Pituitary Function Tests; Pyrogens; Rats | 1970 |
The neurological effects of methyl bromide poisoning.
Topics: Adult; Amobarbital; Brain Diseases; Bromine; Cerebellar Ataxia; Diazepam; Dimercaprol; Electroencephalography; Fumigation; Gas Poisoning; Humans; Hydrocarbons, Halogenated; Male; Mental Disorders; Peripheral Nervous System Diseases; Phenobarbital; Phenytoin; Time Factors | 1971 |
Drug treatment of convulsive disorders.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Adult; Anticonvulsants; Barbiturates; Child; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Myoclonus; Oxazoles; Phenobarbital; Phenytoin; Primidone; Pyrrolidinones; Seizures; Trimethadione | 1972 |
Progressive myoclonus with epilepsy.
Topics: Adult; Child; Chlordiazepoxide; Epilepsy; Female; Humans; Inclusion Bodies; Lipidoses; Myoclonic Cerebellar Dyssynergia; Myoclonus; Neurologic Examination; Phenobarbital; Phenytoin; Prognosis | 1972 |
Phenobarbital-induced alterations in vitamin D metabolism.
Topics: Adult; Animals; Anticonvulsants; Cholecalciferol; Chromatography, Thin Layer; Enzyme Induction; Female; Half-Life; Humans; Hydroxycholecalciferols; Metabolic Clearance Rate; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Osteomalacia; Phenobarbital; Phenytoin; Rats; Tritium | 1972 |
Influence of phenobarbital and diphenylhydantoin on vitamin D metabolism and calcium retention in rats.
Topics: Animals; Anticonvulsants; Calcium; Calcium Isotopes; Carbon Isotopes; Cholecalciferol; Diuresis; Hydroxycholecalciferols; Kidney; Liver; Male; Osteomalacia; Phenobarbital; Phenytoin; Rats; Time Factors; Tritium; Whole-Body Counting | 1972 |
Benzodiazepines and posttetanic potentiation in sympathetic ganglia of the bullfrog.
Topics: Action Potentials; Animals; Anticonvulsants; Anura; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Ganglia, Autonomic; Phenobarbital; Phenytoin; Rana catesbeiana; Synaptic Transmission | 1973 |
[Severe rachitic osteopathy during long-term anticonvulsant treatment].
Topics: Administration, Oral; Alkaline Phosphatase; Anticonvulsants; Biopsy; Calcium; Carbamazepine; Child; Cholecalciferol; Epilepsy, Tonic-Clonic; Humans; Ilium; Iron; Long-Term Care; Male; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone; Rickets | 1973 |
Peripheral nerve function in long-term therapy with diphenylhydantoin. A clinical and electrophysiologic correlation.
Topics: Adult; Aged; Carbamazepine; Electric Stimulation; Electromyography; Epilepsy; Ethosuximide; Evoked Potentials; Female; Folic Acid; Humans; Male; Median Nerve; Middle Aged; Neural Conduction; Peripheral Nerves; Peripheral Nervous System Diseases; Peroneal Nerve; Phenobarbital; Phenytoin; Primidone; Reaction Time; Reflex, Monosynaptic; Sural Nerve; Time Factors; Vitamin B 12 | 1974 |
Nerve conduction velocity in patients on long-term diphenylhydantoin therapy.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Drug Therapy, Combination; Electrodiagnosis; Epilepsy; Female; Humans; Male; Median Nerve; Middle Aged; Neural Conduction; Peripheral Nervous System Diseases; Peroneal Nerve; Phenobarbital; Phenytoin; Reaction Time; Time Factors; Ulnar Nerve | 1974 |
Iatrogenic disorders in epilepsy.
Topics: Adrenal Insufficiency; Anemia, Macrocytic; Animals; Anticonvulsants; Cats; Cerebellar Diseases; Drug Therapy, Combination; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Hypothyroidism; Metabolic Diseases; Peripheral Nervous System Diseases; Phenobarbital; Phenytoin; Rats; Rickets; Seizures | 1970 |
[Anticonvulsants and vitamin D metabolism (author's transl)].
Topics: Animals; Anticonvulsants; Avitaminosis; Body Weight; Calcium; Calcium Radioisotopes; Cholecalciferol; Enzyme Induction; Epilepsy; Humans; Hypocalcemia; Intestinal Absorption; Liver; Long-Term Care; Mice; Osteomalacia; Phenobarbital; Phenytoin; Rats; Vitamin D | 1974 |
Neonatal effects of maternal treatment with the anticonvulsant drug diphenylhydantoin.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Blood Coagulation Disorders; Epilepsy; Female; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Risk Factors | 1971 |
Clinical experience with sulthiame (Ospolot).
Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Epilepsy, Temporal Lobe; Female; Humans; Intellectual Disability; Male; Mental Disorders; Middle Aged; Phenobarbital; Phenytoin; Primidone; Thiazines | 1966 |
On the neurotoxic effects induced by alkylating agents.
Topics: Alanine; Animals; Anti-Bacterial Agents; Antimetabolites; Azaserine; Behavior, Animal; Central Nervous System; Chlorambucil; Cyclophosphamide; Cysteine; Drug Antagonism; Glycine; Male; Mannitol; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Phenobarbital; Phenytoin; Rats; Seizures; Spasm; Thiourea; Triethylenemelamine; Tryptophan | 1966 |
Motor convulsions and EEG during maximal electroshock in the rat.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Cornea; Electric Stimulation; Electroencephalography; Electroshock; Muscles; Phenobarbital; Phenytoin; Primidone; Rats; Seizures; Stress, Physiological; Succinimides; Thiazines; Trimethadione | 1967 |
Magnetic and spectrophotometric properties of the microsomal carbon monoxide binding pigment.
Topics: Animals; Carbon Monoxide; Chlordan; Coloring Agents; Cytochromes; DDT; Diphenhydramine; Electron Spin Resonance Spectroscopy; Fasting; Ferrocyanides; Hydrogen-Ion Concentration; Liver; Microsomes; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Pigments, Biological; Rabbits; Rats; Spectrophotometry | 1967 |
Evaluation of a new convulsant for anticonvulsant screening.
Topics: Acetazolamide; Animals; Anticonvulsants; Cats; Central Nervous System Stimulants; Chlordiazepoxide; Diazepam; Ethosuximide; Female; Male; Mice; Phenobarbital; Phenytoin; Pyrimidines; Thiazines; Trimethadione | 1967 |
Determination of phenobarbital and phenytoin in serum by ultraviolet spectrophotometry.
Topics: Barbiturates; Chromatography, Thin Layer; Humans; Phenobarbital; Phenytoin; Salicylamides; Spectrophotometry; Sulfadimethoxine; Sulfamethoxypyridazine; Thiazines; Trimethadione; Ultraviolet Rays | 1967 |
The effect of selected drugs on the "emotional" behavior elicited via hypothalamic stimulation.
Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Cats; Chlorpromazine; Depression, Chemical; Electric Stimulation; Emotions; Hypothalamus; Imipramine; Meprobamate; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Pregnanediones; Reserpine; Scopolamine; Stimulation, Chemical; Strychnine; Tremorine | 1968 |
The origin of epileptiform seizures caused by oil of Artemisia caerulescens L.
Topics: Aminobenzoates; Animals; Behavior, Animal; Cerebral Decortication; Magnoliopsida; Mephenesin; Mice; Oils; Phenobarbital; Phenylacetates; Phenytoin; Plant Extracts; Respiration; Seizures; Substance P; Urea | 1968 |
Increased susceptibility of mice to seizures after some anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Bemegride; Central Nervous System Stimulants; Drug Synergism; Electroshock; Ethionine; Female; Hydantoins; Male; Methods; Mice; Oxazines; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Rats; Seizures; Trimethadione | 1967 |
The effect of diphenyl-piperazine compounds and other agents on diphenylhydantoin, zoxazolamine and hexobarbital metabolism.
Topics: Animals; Benzopyrenes; Cyclizine; DDT; Diphenhydramine; Endoplasmic Reticulum; Hexobarbital; Humans; Hydroxyzine; Liver; Male; Meclizine; Methylcholanthrene; Mice; Microscopy, Electron; Phenethylamines; Phenobarbital; Phenytoin; Piperazines; Trifluoperazine; Zoxazolamine | 1968 |
Removal of plasma metyrapone in rats submitted to previous pharmacological treatment.
Topics: Animals; Diazepam; Female; Hydrocortisone; Liver; Meprobamate; Metyrapone; Nikethamide; Pentaerythritol Tetranitrate; Phenobarbital; Phenylbutazone; Phenytoin; Rats | 1969 |
Effects of dilantin and phenobarbitone on histamine and antihistamine activity in various dog tissues.
Topics: Animals; Dogs; Gingiva; Gingival Hyperplasia; Histamine; Histamine H1 Antagonists; Liver; Parotid Gland; Phenobarbital; Phenytoin; Submandibular Gland; Tissue Extracts | 1969 |
Epilepsy.
Topics: Adult; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Folic Acid Deficiency; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Primidone; Psychoses, Substance-Induced; Thiazines | 1969 |
Drug treatment of epilepsy in childhood.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Paraldehyde; Phenobarbital; Phenytoin; Primidone; Thiazines | 1969 |
The in vivo and in vitro effect of diphenylhydantoin and phenobarbitone on K+ activated phosphohydrolase and (Na+, K+)-activated ATPase in particulate membrane fractions from rat brain.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Biological Transport, Active; Brain; Cell Membrane; In Vitro Techniques; Male; Phenobarbital; Phenytoin; Phosphoric Monoester Hydrolases; Potassium; Rats; Sodium | 1970 |
Response of female mice to anticonvulsants after pretreatment with sex steroids.
Topics: Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Drug Synergism; Female; Lynestrenol; Mestranol; Mice; Phenobarbital; Phenytoin; Proadifen | 1970 |
Metabolism of diphenylhydantoin by rat liver microsomes. I. characteristics of the reaction.
Topics: Adenosine Triphosphate; Animals; Azides; Biotransformation; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Diethylstilbestrol; Dimenhydrinate; Disulfiram; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isoniazid; Kinetics; Male; Methylene Blue; Microsomes, Liver; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Proadifen; Prochlorperazine; Rats; Sodium; Temperature | 1970 |
Interference of barbiturates with pyrimidine incorporation. II. Structural specificity of the inhibition of orotate uptake in Bacillus cereus.
Topics: Amobarbital; Bacillus cereus; Barbiturates; Bemegride; Biological Transport; Carbon Isotopes; Carboxylic Acids; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Chlorpromazine; Glutethimide; Hexobarbital; Hydantoins; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Orotic Acid; Pentobarbital; Phenobarbital; Phenytoin; Primidone; Solubility; Succinimides; Thiopental; Thymine; Trimethadione; Tromethamine; Uracil; Urea | 1970 |
Anticonvulsant drugs in idiopathic epilepsy.
Topics: Acetazolamide; Anticonvulsants; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Hydantoins; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome; Succinimides; Urea | 1970 |
A comprehensive scheme for the evaluation of anticonvulsant concentrations in blood using thin-layer chromatography.
Topics: Acetazolamide; Anticonvulsants; Benzazepines; Carbamazepine; Chlordiazepoxide; Chromatography, Thin Layer; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Nitro Compounds; Oxazepam; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines | 1971 |
Massive hepatic necrosis after fluroxene anesthesia--a case of drug interaction?
Topics: Aged; Anesthesia, Inhalation; Anesthetics; Autopsy; Chemical and Drug Induced Liver Injury; Drug Interactions; Ethers; Female; Fluorine; Humans; Liver; Necrosis; Phenobarbital; Phenytoin | 1972 |
[Medical treatment of epilepsy].
Topics: Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Phenobarbital; Phenytoin; Thiazines | 1971 |
[Protection against phenylisothiocyanate by various steroids, phenobarbitone and diphenylhydantoin].
Topics: Animals; Drug Interactions; Female; Phenobarbital; Phenytoin; Rats; Steroids; Thiocyanates | 1972 |
Serum -glytamyl transpeptidase activity in liver disease.
Topics: Acyltransferases; Adolescent; Adult; Aged; Alkaline Phosphatase; Aspartate Aminotransferases; Barbiturates; Biliary Tract Diseases; Bone Diseases; Child; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Isocitrate Dehydrogenase; Liver Diseases; Male; Middle Aged; Nucleotidases; Phenobarbital; Phenytoin | 1972 |
Anticonvulsant drugs. I. Patho-physiological and pharmacological aspects.
Topics: Acetates; Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Dibenzazepines; Electroencephalography; Epilepsies, Partial; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Succinimides; Thiazines; Trimethadione | 1972 |
The influence of anticonvulsant drugs on formyl tetrahydrofolic acid stimulation of rat brain respiration in vitro.
Topics: Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; In Vitro Techniques; Leucovorin; Male; Microsomes; Norepinephrine; Oxygen Consumption; Phenobarbital; Phenytoin; Primidone; Rats; Scopolamine; Synaptosomes; Thiazines | 1972 |
The use of stable isotopes in gas chromatography-mass spectrometric studies of drug metabolism.
Topics: Amobarbital; Animals; Barbiturates; Body Fluids; Carbon Isotopes; Chromatography, Gas; Colostrum; Computers; Diazepam; Isotope Labeling; Mass Spectrometry; Microchemistry; Milk; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Pressure; Secobarbital | 1974 |
[Micro-method for the quantitative determination of sedatives and antipyretics (aminophenazone, diphenylhydantoin, paracetamol, phenobarbital, primidone) using thermo-gas chromatography].
Topics: Acetaminophen; Aminopyrine; Analgesics; Chromatography, Gas; Hypnotics and Sedatives; Methods; Microchemistry; Phenobarbital; Phenytoin; Primidone; Temperature | 1974 |
An evaluation of a drug administration system in a psychiatric hospital.
Topics: Acetaminophen; Antidepressive Agents; Benzodiazepinones; Hospitals, Psychiatric; Humans; Medication Errors; Medication Systems, Hospital; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Salicylates; Scotland | 1974 |
Letter: Sleep epilepsy.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Delayed-Action Preparations; Dextroamphetamine; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Sleep Wake Disorders | 1974 |
Movement disorder as a manifestation of diphenylhydantoin toxicity.
Topics: Administration, Oral; Child; Humans; Male; Movement Disorders; Phenobarbital; Phenytoin; Succinimides | 1974 |
Status epilepticus.
Topics: Diazepam; Epilepsy; Humans; Hypocalcemia; Hypoglycemia; Magnesium Deficiency; Paraldehyde; Phenobarbital; Phenytoin; Recurrence; Vitamin B 6 Deficiency | 1974 |
Effect on pseudoconditioning of drugs with known central nervous activity.
Topics: Amobarbital; Animals; Avoidance Learning; Behavior, Animal; Caffeine; Cannabis; Chlorpromazine; Conditioning, Psychological; Depression, Chemical; Diazepam; Dibenzylchlorethamine; Female; Meprobamate; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rats; Stimulation, Chemical; Strychnine; Trimethadione | 1974 |
Letter: Anticonvulsants and vitamin D metabolism.
Topics: Child; Drug Therapy, Combination; Epilepsy; Humans; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Rickets | 1974 |
[Drug permeation through synthetic lipid membranes. Permeability of lecithin-collodium membranes for drugs and metabolites].
Topics: Buffers; Caffeine; Diffusion; Hexobarbital; Hydrogen-Ion Concentration; Kinetics; Membranes, Artificial; Models, Chemical; Papaverine; Phenobarbital; Phenytoin; Phosphatidylcholines; Quinine; Salicylates; Solutions; Time Factors | 1974 |
Epileptiform seizures in domestic fowl. IV. The effects of anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Chickens; Diazepam; Electroencephalography; Phenobarbital; Phenytoin; Photic Stimulation; Seizures; Trimethadione | 1974 |
Serum immunoglobulins in epilepsy.
Topics: Adult; Drug Therapy, Combination; Epilepsy; Erythrocytes; Female; Folic Acid; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Male; Phenobarbital; Phenytoin; Primidone | 1974 |
Simultaneous determination of some antiepileptic drugs by gas-liquid chromatography.
Topics: Analysis of Variance; Carbamazepine; Chromatography, Gas; Colorimetry; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin; Primidone; Spectrophotometry | 1974 |
A morphometric study of the endoplasmic reticulum in human hepatocytes. Correlation between morphological and biochemical data in subjects under treatment with certain drugs.
Topics: Biopsy; Carbon Radioisotopes; Cell Membrane; Cell Nucleus; Cholesterol; Diazepam; Endoplasmic Reticulum; Gilbert Disease; Golgi Apparatus; Humans; Liver; Liver Glycogen; Microscopy, Electron; Mitochondria, Liver; Phenobarbital; Phenytoin | 1974 |
A study of the development of tolerance to an anticonvulsant effect of delta9-tetrahydrocannabinol and cannabidiol.
Topics: Animals; Anticonvulsants; Cannabis; Dronabinol; Drug Interactions; Drug Synergism; Drug Tolerance; Electroshock; Hexobarbital; Male; Mice; Mice, Inbred ICR; Phenobarbital; Phenytoin; Resorcinols; Sleep; Terpenes; Time Factors | 1974 |
[Osteomalacia caused by anticonvulsive drugs case-report (author's transl)].
Topics: Adult; Aged; Anticonvulsants; Female; Humans; Male; Osteomalacia; Phenobarbital; Phenytoin | 1974 |
Do anticonvulsants have a teratogenic effect?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Child, Preschool; Cleft Lip; Cleft Palate; Congenital Abnormalities; Epilepsy; Female; Heart Defects, Congenital; Humans; Infant; Infant Mortality; Infant, Newborn; Intellectual Disability; Male; Mephobarbital; Minnesota; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Primidone; Teratogens | 1974 |
[Plasma diphenylhydantoin concentration in epileptic patients].
Topics: Drug Interactions; Epilepsy; Humans; Phenobarbital; Phenytoin | 1974 |
Broad-spectrum simultaneous GLC assay of nonderivatized antiepileptic drugs.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Trimethadione | 1974 |
[Considerations and research on febrile convulsions].
Topics: Anticonvulsants; Brain Diseases; Child, Preschool; Diagnosis, Differential; Diazepam; Electroencephalography; Epilepsy; Female; Fever; Humans; Infant; Male; Mannitol; Phenobarbital; Phenytoin; Primidone; Seizures | 1974 |
[Special viewpoints in the treatment with anticonvulsants in childhood. Value of determination of serum level of anticonvulsants in the treatment of seizures].
Topics: Adolescent; Anticonvulsants; Child, Preschool; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1974 |
Iatrogenic nutritional effects of anticonvulsants.
Topics: Adolescent; Adult; Anticonvulsants; Blood Coagulation Disorders; Bone Diseases; Child; Child, Preschool; Connective Tissue; Endocrine Glands; Enzyme Induction; Epilepsy; Female; Folic Acid Deficiency; Humans; Iatrogenic Disease; Infant; Infant, Newborn; Liver; Nutrition Disorders; Phenobarbital; Phenytoin; Pregnancy; Primidone; Pyridoxine; Vitamin D Deficiency | 1974 |
[Problems in use of anti-epileptics. 1. Relationship between dosage, blood level and effect].
Topics: Adolescent; Child; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Phenobarbital; Phenytoin | 1974 |
Letter: Effect of phenytoin on serum phenobarbitone levels.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1974 |
Plasma albumin concentration and binding of diphenylhydantoin in man.
Topics: Adolescent; Adult; Aged; Aspirin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Penicillin G; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin | 1974 |
Phenobarbital-induced coagulation defects in cats.
Topics: Alanine Transaminase; Animals; Animals, Newborn; Blood Coagulation; Blood Coagulation Disorders; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Factor V Deficiency; Factor VII; Factor VII Deficiency; Female; Folic Acid; Hemophilia A; Hypoprothrombinemias; Liver; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Primidone; Rats; Vitamin K | 1974 |
Sympodia.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Abnormalities, Severe Teratoid; Autopsy; Epilepsy; Female; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Radiography; Singapore | 1974 |
Effects of age, sex, obesity, and pregnancy on plasma diphenylhydantoin levels.
Topics: Adolescent; Adult; Age Factors; Analysis of Variance; Chromatography, Gas; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Kinetics; Male; Middle Aged; Obesity; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Regression Analysis; Sex Factors; Spectrophotometry | 1974 |
Augmentation of cerebellar Purkinje cell discharge rate after diphenylhydantoin.
Topics: Acetazolamide; Action Potentials; Cerebellum; Electroencephalography; Epilepsy; Phenobarbital; Phenytoin; Purkinje Cells; Trimethadione | 1972 |
Effects of diphenylhydantoin and other antiepileptic drugs on epileptiform activity and Purkinje cell discharge rates.
Topics: Acetazolamide; Action Potentials; Animals; Anticonvulsants; Blood Pressure; Cats; Cerebellum; Electroencephalography; Epilepsy; Penicillins; Phenobarbital; Phenytoin; Purkinje Cells; Trimethadione | 1972 |
Influence of diphenylhydantoin and phenobarbital on intestinal calcium transport in the rat.
Topics: Animals; Binding, Competitive; Calcium; Calcium Isotopes; Calcium Metabolism Disorders; Epilepsy; Intestinal Absorption; Male; Phenobarbital; Phenytoin; Proteins; Rats; Vitamin D Deficiency | 1972 |
The effects of some anticonvulsant drugs on cobalt-induced epilepsy.
Topics: Animals; Cobalt; Electroencephalography; Epilepsy; Ethosuximide; Evaluation Studies as Topic; Frontal Lobe; Male; Phenobarbital; Phenytoin; Rats | 1973 |
Acute dextropropoxyphene hydrochloride (Darvon) poisoning.
Topics: Adolescent; Brain Damage, Chronic; Dextropropoxyphene; Diazepam; Female; Humans; Nalorphine; Phenobarbital; Phenytoin; Poisoning; Respiratory Tract Diseases; Seizures; Suicide; Ventilators, Mechanical | 1973 |
Anticonvulsant drug-serum levels in psychiatric patients with seizure disorders. Effects of certain psychotropic drugs.
Topics: Chlorpromazine; Chromatography, Gas; Diazepam; Drug Interactions; Epilepsy; Humans; Mental Disorders; Phenobarbital; Phenytoin; Thioridazine | 1974 |
[Acute leukemia induced by diphenylhydantoin? Apropos of 4 cases].
Topics: Adult; Bone Marrow; Drug Therapy, Combination; Epilepsy; Female; Humans; Leukemia, Lymphoid; Lung; Lymph Nodes; Male; Pharynx; Phenobarbital; Phenytoin; Spleen | 1973 |
Seizures associated with the use of meglumine iothalamate 60 per cent in ventriculography.
Topics: Adult; Brain; Cerebral Ventriculography; Child; Curare; Diazepam; Electroencephalography; Female; Humans; Infant, Newborn; Iothalamic Acid; Male; Middle Aged; Phenobarbital; Phenytoin; Respiratory Insufficiency; Seizures | 1972 |
Protection against the neurolathyrism produced by arsanilic acid in the rat.
Topics: 5-Hydroxytryptophan; Animals; Arsenic Poisoning; Biotransformation; Desoxycorticosterone; Female; Hormones; Movement Disorders; Phenobarbital; Phenytoin; Pregnenolone; Rats; Serotonin; Steroids; Thyroxine; Triamcinolone | 1972 |
Anticonvulsant activity of delta9-tetrahydrocannabilol and its 11-hydroxy and 8alpha, 11-dihydroxy metabolites in the frog.
Topics: Animals; Anticonvulsants; Brain; Brain Chemistry; Cannabis; Dronabinol; Electroshock; Female; Hydroxylation; Male; Phenobarbital; Phenytoin; Rana pipiens; Time Factors; Tritium | 1974 |
Excitable membrane stabilization by diphenylhydantoin and calcium.
Topics: Acetylcholine; Action Potentials; Animals; Calcium; Cell Membrane Permeability; Electrodes; Evoked Potentials; In Vitro Techniques; Membranes; Neuromuscular Junction; Phenobarbital; Phenytoin; Rana pipiens; Time Factors | 1974 |
The antagonism of hippocampal and cortical afterdischarge by SC-13504, a new anticonvulsant.
Topics: Animals; Anticonvulsants; Arousal; Behavior, Animal; Benzene Derivatives; Cats; Cerebral Cortex; Depression, Chemical; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Evoked Potentials; Hippocampus; Male; Phenobarbital; Phenytoin; Piperazines; Pyridines; Stereotaxic Techniques; Structure-Activity Relationship; Thalamus | 1974 |
Effects of diazepam and phenobarbital on electrically-induced amygdaloid seizures and seizure development.
Topics: Amygdala; Animals; Diazepam; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Male; Models, Neurological; Neural Conduction; Neurons; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Stereotaxic Techniques | 1974 |
Diazepam as an oral long-term anticonvulsant for epileptic mental patients.
Topics: Amobarbital; Anticonvulsants; Diazepam; Epilepsy; Evaluation Studies as Topic; Female; Humans; Long-Term Care; Male; Phenobarbital; Phenytoin; Psychiatric Status Rating Scales; Psychotic Disorders | 1972 |
A medical and social survey of 231 children with seizures.
Topics: Adolescent; Attitude to Health; Child; Child Behavior Disorders; Child, Preschool; Electroencephalography; Employment; Encephalitis; Epilepsy; Epilepsy, Absence; Ethosuximide; Female; Greece; Humans; Infant; Intelligence; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Seizures; Socioeconomic Factors | 1972 |
Variation in response to anticonvulsants in a group of epileptic patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Chromatography, Gas; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Sex Factors | 1972 |
The action of some anticonvulsant drugs on cobalt-induced epilepsy and on the bemegride threshold in alert cats.
Topics: Animals; Anticonvulsants; Bemegride; Carbamazepine; Cats; Cobalt; Diazepam; Electroencephalography; Epilepsies, Partial; Epilepsy; Phenobarbital; Phenytoin | 1972 |
Megaloblastic anemia after anticonvulsive therapy.
Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Epilepsies, Partial; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1972 |
Long term anticonvulsant therapy and cerebellar atrophy.
Topics: Adult; Avitaminosis; Cerebellar Diseases; Cranial Fossa, Posterior; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Humans; Phenobarbital; Phenytoin; Pneumoencephalography; Primidone | 1973 |
Relation of prophylactic medication to the occurrence of early seizures following craniocerebral trauma.
Topics: Brain Edema; Brain Injuries; Dexamethasone; Epilepsy, Post-Traumatic; Humans; Military Medicine; Phenobarbital; Phenytoin; Prognosis; United States; Vietnam | 1973 |
A survey of attitudes toward the pharmacological prophylaxis of posttraumatic epilepsy.
Topics: Anticonvulsants; Attitude of Health Personnel; Craniocerebral Trauma; Epilepsy, Post-Traumatic; Humans; Phenobarbital; Phenytoin | 1973 |
Prevention by catatoxic steroids of lithocholic acid-induced biliary concrements in the rat.
Topics: Animals; Bile Acids and Salts; Body Weight; Common Bile Duct; Female; Gallstones; Jaundice; Lithocholic Acid; Liver; Nitriles; Phenobarbital; Phenytoin; Prednisolone; Propionates; Rats; Steroids; Thyroxine; Triamcinolone; Triiodothyronine | 1972 |
Medical management of closed head injuries.
Topics: Adolescent; Adult; Aged; Airway Obstruction; Anti-Bacterial Agents; Blood Transfusion; Cerebral Angiography; Cerebral Hemorrhage; Child; Craniocerebral Trauma; Decerebrate State; Embolism, Fat; Glucocorticoids; Humans; Hyperbaric Oxygenation; Hypothermia, Induced; Intracranial Pressure; Intubation, Intratracheal; Mannitol; Middle Aged; Monitoring, Physiologic; Neurologic Examination; Phenobarbital; Phenytoin; Plasma Substitutes; Pneumonia, Aspiration; Urea | 1972 |
Surgical management of head injuries in children in the acute phase.
Topics: Adolescent; Age Factors; Cerebral Angiography; Child; Child, Preschool; Craniocerebral Trauma; Female; Hematoma, Epidural, Cranial; Hematoma, Subdural; Humans; Infant; Infant, Newborn; Male; Neurologic Examination; Phenobarbital; Phenytoin; Skull Fractures; Spinal Puncture; Unconsciousness | 1972 |
Selected pharmacological studies of succinic semialdehyde.
Topics: Aldehydes; Animals; Arrhythmias, Cardiac; Blood Pressure; Central Nervous System; Chromatography, Gas; Chromatography, Paper; Electroshock; Heart; Ileum; Male; Motor Neurons; Muscle, Smooth; Muscles; Phenobarbital; Phenytoin; Rats; Spectrophotometry, Infrared; Succinates | 1972 |
[Osteomalacia due to a long-term antiepileptic treatment].
Topics: Anticonvulsants; Calcium; Female; Humans; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Time Factors; Vitamin D | 1972 |
Protection by catatoxic steroids, phenobarbital and diphenylhydantoin against methaqualone intoxication.
Topics: Androstenes; Animals; Enzyme Induction; Ethylestrenol; Female; Hydroxysteroids; Ketosteroids; Methaqualone; Movement Disorders; Nitriles; Norsteroids; Oxandrolone; Phenobarbital; Phenytoin; Pregnenolone; Propionates; Rats; Spironolactone; Steroids | 1972 |
Effect of certain drugs and environmental agents on microsomal enzyme systems.
Topics: Aminopyrine N-Demethylase; Animals; Anisoles; Aspirin; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Intestine, Small; Kidney; Lung; Male; Microsomes; Microsomes, Liver; Morphinans; Nitro Compounds; Oxidoreductases, N-Demethylating; Phenacetin; Phenanthrenes; Phenobarbital; Phenytoin; Rats; Transferases; Trifluoperazine | 1972 |
Clinical conference: megaloblastic anemia associated with anticonvulsant drugs.
Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Female; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone | 1972 |
Relationships between serum and cerebrospinal fluid anticonvulsant drug and folic acid concentrations in epileptic patients.
Topics: Adult; Chromatography, Gas; Epilepsy; Female; Folic Acid; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1972 |
Toxic encephalopathy with seizures secondary to ingestion of composition C-4. A clinical and electroencephalographic study.
Topics: Adult; Brain Diseases; Electroencephalography; Epilepsy; Explosions; Humans; Male; Military Medicine; Nitrites; Phenobarbital; Phenytoin | 1972 |
The simultaneous determination of multiple anticonvulsant drug levels by gas-liquid chromatography. Method and clinical application.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Chromatography, Gas; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Methods; Methylphenidate; Phenobarbital; Phenytoin; Primidone | 1972 |
[Effects of various pharmacological agents on neocortical seizure activities in the rabbit].
Topics: Aminobutyrates; Animals; Cerebral Cortex; Cocaine; Electric Stimulation; Electroencephalography; Evoked Potentials; Lidocaine; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rabbits; Strychnine | 1972 |
Improved microdetermination for diphenylhydantoin in blood by UV spectrophotometry.
Topics: Animals; Benzophenones; Humans; Male; Methods; Microchemistry; Oxidation-Reduction; Phenobarbital; Phenytoin; Rabbits; Spectrophotometry, Ultraviolet; Temperature; Time Factors | 1973 |
A gas-chromatographic method for the simultaneous determination of phenobarbitone, primidone and phenytoin in serum using a nitrogen detector.
Topics: Chromatography, Gas; Electrodes; Humans; Indicators and Reagents; Methods; Methylation; Nitrogen; Phenobarbital; Phenytoin; Primidone | 1973 |
Follow-up of epileptic outpatients.
Topics: Adolescent; Adult; Aged; Educational Status; Employment; Epilepsy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Rehabilitation, Vocational; Surveys and Questionnaires | 1973 |
Drugs for convulsions.
Topics: Adult; Child; Child, Preschool; Diazepam; Humans; Phenobarbital; Phenytoin; Seizures; Stevens-Johnson Syndrome; Sulfonamides | 1973 |
Leucine aminopeptidase isoenzyme changes after treatment with anticonvulsant drugs.
Topics: Blood Protein Electrophoresis; Blood Proteins; Epilepsy; Humans; Isoenzymes; Jaundice; Leucyl Aminopeptidase; Phenobarbital; Phenytoin; Primidone | 1973 |
The determination of phenobarbital and diphenylhydantoin in blood by differential pulse polarography.
Topics: Chromatography, Thin Layer; Humans; Methods; Microchemistry; Phenobarbital; Phenytoin; Polarography; Solutions | 1973 |
Antiserum to diphenylhydantoin: preparation and characterization.
Topics: Animals; Antibody Formation; Carbon Isotopes; Cross Reactions; Dimethylformamide; Female; Male; Phenobarbital; Phenytoin; Rabbits; Radioimmunoassay; Serum Albumin, Bovine; Tritium; Valerates | 1973 |
Anticonvulsant modification of tripelennamine effects on the electrographic activity of the cat brain.
Topics: Animals; Anticonvulsants; Brain; Cats; Cerebral Cortex; Electroencephalography; Hippocampus; Phenobarbital; Phenytoin; Tripelennamine | 1973 |
Diphenylhydantoin inferference with spectraphotometric barbiturate estimations.
Topics: Humans; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet | 1973 |
Simultaneous determination of carbamazapine ("Tegretol") and other anticonvulsants in human plasma by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Computers; Dibenzazepines; Humans; Hydantoins; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Quaternary Ammonium Compounds | 1973 |
Epilepsy and pregnancy: a report from the Oxford Record Linkage Study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Age Factors; Child; Congenital Abnormalities; Drug Synergism; England; Epilepsy; Female; Fetal Death; Humans; Male; Medical Records; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Social Class | 1973 |
GC assay of phenobarbital.
Topics: Amides; Benzene Derivatives; Chromatography, Gas; Humans; Malonates; Phenobarbital; Phenytoin; Primidone; Quaternary Ammonium Compounds | 1973 |
Diencephalic autonomic epilepsy caused by a neoplasm.
Topics: Astrocytoma; Autonomic Nervous System; Brain Neoplasms; Diencephalon; Epilepsy; Female; Humans; Infant; Phenobarbital; Phenytoin; Radionuclide Imaging | 1973 |
The effect of anticonvulsant drugs in vitro on bone calcium mobilization by parathyroid hormone.
Topics: Animals; Bone and Bones; Calcium; Calcium Isotopes; In Vitro Techniques; Mice; Parathyroid Hormone; Phenobarbital; Phenytoin | 1973 |
A comparison of the anticonvulsant, neurotoxic and lethal effects of diphenylbarbituric acid, phenobarbital and diphenylhydantoin in the mouse.
Topics: Animals; Anticonvulsants; Barbiturates; Dose-Response Relationship, Drug; Electroshock; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Neurologic Manifestations; Pentylenetetrazole; Phenobarbital; Phenytoin; Reflex; Seizures | 1973 |
Use of stable isotopes in measuring low concentrations of drugs and drug metabolites by GC-MS-COM procedures.
Topics: Amniotic Fluid; Barbiturates; Caffeine; Carbon Isotopes; Child; Chromatography, Gas; Colostrum; Computers; Fatty Acids; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Male; Mass Spectrometry; Maternal-Fetal Exchange; Methods; Microchemistry; Milk, Human; Phenobarbital; Phenytoin; Pregnancy | 1973 |
Chronic and severe phenobarbital intoxication in a child treated with primidone and diphenylhydantoin.
Topics: Anticonvulsants; Biotransformation; Chromatography, Gas; Drug Interactions; Female; Humans; Infant; Infant, Newborn; Phenobarbital; Phenytoin; Primidone; Seizures | 1973 |
Acceleration of peritoneal dialysis with minimal N-myristyl-beta-aminopropionate.
Topics: Adsorption; Amines; Amobarbital; Animals; Barbiturates; beta-Alanine; Carbon Isotopes; Lethal Dose 50; Male; Mice; Peritoneal Dialysis; Phenobarbital; Phenytoin; Propionates; Rabbits; Salicylates; Surface-Active Agents; Urea | 1973 |
Routine identification of drugs of abuse in human urine. 3. Differential elution of the XAD-2 resin.
Topics: Amitriptyline; Amphetamine; Barbiturates; Chromatography, Thin Layer; Dextropropoxyphene; Humans; Hydrogen-Ion Concentration; Methods; Pharmaceutical Preparations; Phenobarbital; Phenylpropanolamine; Phenytoin; Quinine; Resins, Plant; Solvents; Substance-Related Disorders | 1973 |
[Severe osteomalacic rickets induced by antiepileptic drugs. Literature review apropos of a case].
Topics: Child; Child, Preschool; Humans; Male; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Rickets; Vitamin D | 1973 |
Isoquinolines. 3. 3-Aminoisoquinoline derivatives with central nervous system depressant activity.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Behavior, Animal; Blood Pressure; Cats; Central Nervous System; Depression, Chemical; Electroshock; Heart Rate; Isoquinolines; Mice; Motor Activity; Pentylenetetrazole; Phenobarbital; Phenytoin; Structure-Activity Relationship; Strychnine | 1973 |
[Morphological and pharmacological-toxicological aspects of hyperoxia].
Topics: Aminobutyrates; Animals; Atmospheric Pressure; Brain Diseases; Diazepam; Ganglia; Humans; Lung; Lung Diseases; Muscle Cramp; Oxygen; Partial Pressure; Phenobarbital; Phentolamine; Phenytoin; Pulmonary Edema; Rats; Time Factors; Trimethadione; Tromethamine | 1973 |
Vitamin D-dependent rickets in institutionalized, mentally retarded children receiving long-term anticonvulsant therapy. I. A survey of 288 patients.
Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Calcium; Child; Child, Preschool; Female; Humans; Infant; Intellectual Disability; Magnesium; Male; Mephobarbital; Mesoridazine; Phenobarbital; Phenytoin; Phosphorus; Potassium; Primidone; Rickets; Seizures; Sodium; Succinimides; Vitamin D | 1973 |
Pheneturide, a more potent liver enzyme inducer in man than phenobarbitone?
Topics: Adipates; Anticonvulsants; Enzyme Induction; Epilepsy; Female; Humans; Liver; Male; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Sugar Acids; Urea | 1973 |
The effect of some anticonvulsant drugs on leptazol and bicuculline induced acetylcholine efflux from rat cerebral cortex.
Topics: Acetylcholine; Alkaloids; Animals; Anticonvulsants; Cerebral Cortex; Dioxoles; Dose-Response Relationship, Drug; Electroencephalography; Isoquinolines; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Seizures; Trimethadione | 1973 |
Some studies on the convulsant action of folic acid.
Topics: Alkaloids; Animals; Auditory Threshold; Cerebral Ventricles; Dioxoles; Electroshock; Folic Acid; Folic Acid Antagonists; Glutamates; Injections; Injections, Intravenous; Isoquinolines; Mice; Ouabain; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Seizures; Strychnine | 1973 |
Primidone, diphenylhydantoin and phenobarbital. Aspects of acute and chronic toxicity.
Topics: Ataxia; Chromatography, Gas; Drug Tolerance; Epilepsy; Humans; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone | 1973 |
A radioimmunoassay for diphenylhydantoin.
Topics: Anhydrides; Animals; Antibody Formation; Antibody Specificity; Antigen-Antibody Reactions; Binding Sites, Antibody; Binding, Competitive; Carbon Isotopes; Chickens; Chromatography, Gas; Female; Globulins; Guinea Pigs; Humans; Immune Sera; Phenobarbital; Phenylacetates; Phenytoin; Protein Binding; Rabbits; Radioimmunoassay | 1973 |
The management of febrile convulsions.
Topics: Administration, Oral; Aspirin; Child, Preschool; Diazepam; Fever; Humans; Infant; Injections, Intramuscular; Phenobarbital; Phenytoin; Seizures | 1973 |
Rickets precipitated by anticonvulsant drugs in a child receiving prophylactic vitamin D.
Topics: Adolescent; Alkaline Phosphatase; Calcium; Epilepsy; Female; Humans; Ilium; Phenobarbital; Phenytoin; Phosphorus; Rickets; Vitamin D | 1973 |
Preliminary observations of serum carbamazepine concentration in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1973 |
[Introduction of animal mass psychology in pharmacology. 9. Circadian rhythm of El-mouse convulsions and effect of anticonvulsants on simultaneity at 6 p.m].
Topics: Age Factors; Aminobutyrates; Animals; Anticonvulsants; Behavior, Animal; Circadian Rhythm; Eosinophils; Female; Imidazoles; Male; Mice; Phenobarbital; Phenytoin; Seizures; Time Factors | 1973 |
Methsuximide overdose. Delayed onset of profound coma.
Topics: Administration, Oral; Adolescent; Anticonvulsants; Central Nervous System; Coma; Drug Synergism; Electroencephalography; Female; Humans; Hypokalemia; Phenobarbital; Phenytoin; Pyrrolidinones; Reflex, Abnormal; Time Factors | 1973 |
[Genetic questionnaire. Genetic counseling for a patient with the complex association of G-6-PD deficiency, Gronblad-Strandberg syndrome (pseudo-xanthoma elasticum) and epilepsy].
Topics: Adult; Epilepsy; Favism; Genetic Counseling; Glucosephosphate Dehydrogenase Deficiency; Humans; Kidney Calculi; Male; Phenobarbital; Phenytoin; Pseudoxanthoma Elasticum | 1973 |
The role of antiepileptic blood levels in the treatment of patients with epilepsy.
Topics: Adult; Drug Therapy, Combination; Epilepsy; Female; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1973 |
Dependence of anticonvulsant drug action on central monoamines.
Topics: Animals; Anticonvulsants; Dopamine; Drug Interactions; Electroshock; Ethosuximide; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Norepinephrine; Pentylenetetrazole; Phenobarbital; Phenytoin; Receptors, Drug; Seizures; Serotonin; Time Factors | 1973 |
[Editorial: Antiepileptic agents--folic acid].
Topics: Anemia, Macrocytic; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1973 |
Rapid, simultaneous GLC determination of phenobarbital, primidone, and diphenylhydantoin.
Topics: Chromatography, Gas; Methods; Phenobarbital; Phenytoin; Primidone; Time Factors | 1973 |
The effects of anticonvulsants on in vitro protein synthesis in immature brain.
Topics: Animals; Brain; Carbon Isotopes; In Vitro Techniques; Leucine; Nerve Tissue Proteins; Phenobarbital; Phenytoin; Rats | 1973 |
The influence of phenobarbital and diphenylhydantoin on some blood cation transport systems in epileptics.
Topics: Adolescent; Adult; Aged; Biological Transport; Brain; Child; Child, Preschool; Electrolytes; Epilepsy; Erythrocytes; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Plasma; Potassium; Sodium | 1973 |
Letter: Diphenylhydantoin interference with spectrophotometric barbiturate estimations.
Topics: Barbiturates; Chromatography, Gas; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet | 1973 |
A rapid method for the estimation of anti-epileptic drugs in blood serum by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Epilepsy; Ethosuximide; Evaluation Studies as Topic; Humans; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Succinimides; Temperature; Time Factors; Trimethadione | 1973 |
The teratological effects of anticonvulsants and the effects on pregnancy and birth.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cleft Lip; Cleft Palate; Cyclohexanes; Epilepsy; Ethosuximide; Female; Humans; Hydantoins; Male; Mutation; Obstetric Labor Complications; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Propylamines | 1973 |
Effects of drug pretreatment on antipyrine levels in blood and tissues: an example of multiple drug interactions.
Topics: Animals; Antipyrine; Brain; Brain Chemistry; Drug Interactions; Enzyme Induction; Half-Life; Kinetics; Liver; Male; Phenobarbital; Phenytoin; Proadifen; Rats; Time Factors | 1973 |
Blood serotonin levels in severe mental retardation.
Topics: Age Factors; Blood Pressure; Child; Child, Preschool; Defecation; Diazepam; Diet; Female; Humans; Hydroxyindoleacetic Acid; Infant; Intellectual Disability; Male; Methods; Motor Activity; Muscle Tonus; Neomycin; Phenobarbital; Phenytoin; Serotonin; Sex Factors; Spectrophotometry | 1973 |
Quantitative evaluation of the pentylenetetrazol-anticonvulsant interaction on the EEG of the cat.
Topics: Animals; Anticonvulsants; Cats; Cerebral Cortex; Computers; Drug Interactions; Electroencephalography; Hippocampus; Pentylenetetrazole; Phenobarbital; Phenytoin; Reticular Formation; Thalamus; Time Factors; Trimethadione | 1973 |
The orienting reflex in epilepsy: electrographic data concerning the effect of antiepileptic treatment upon the interictal changes in the orienting reflex. Human data.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Cardiovascular System; Child; Drug Combinations; Electrocardiography; Electromyography; Epilepsy; Female; Humans; Male; Middle Aged; Muscles; Orientation; Phenobarbital; Phenytoin; Pulse; Reflex; Respiration; Spirometry | 1973 |
Influence of phenobarbital and diphenylhydantoin on plasma carbamazepine levels in patients with epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Depression, Chemical; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Pain; Phenobarbital; Phenytoin; Trigeminal Neuralgia | 1973 |
[Complications of medical therapy for epilepsy in children and adolescents].
Topics: Anticonvulsants; Child; Diplopia; Drug Hypersensitivity; Drug Therapy, Combination; Epilepsy; Headache; Humans; Mental Disorders; Movement Disorders; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Speech Disorders; Vertigo | 1973 |
[Antimetabolites of folic acid metabolism with chemotherapeutic activity against rodent malaria (Plasmodium vinckei)].
Topics: Aminopterin; Animals; Cycloheximide; Female; Folic Acid; Folic Acid Antagonists; Hydantoins; Malaria; Male; Methotrexate; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Plasmodium; Primidone; Pyrimethamine; Thalidomide; Triamterene | 1973 |
Effects of inositol, diphenylhydantoin and phenobarbital on HEOD storage in rat adipose tissue.
Topics: Adipose Tissue; Aminopyrine N-Demethylase; Animals; Body Weight; Dieldrin; Inositol; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Time Factors | 1973 |
The influence of diphenylhydantoin on primidone metabolism.
Topics: Drug Interactions; Enzyme Induction; Female; Humans; Liver; Male; Phenobarbital; Phenytoin; Primidone | 1973 |
Correlation of anticonvulsant levels in human plasma and epileptogenic brain.
Topics: Animals; Brain; Cerebral Cortex; Electroencephalography; Epilepsy; Frontal Lobe; Humans; Phenobarbital; Phenytoin; Rats; Temporal Lobe | 1973 |
[Diphenylhydantoin: study of plasmatic concentrations obtained by oral administration and of their antiarrhythmic effects].
Topics: Administration, Oral; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Drug Synergism; Humans; Phenobarbital; Phenytoin | 1973 |
A rapid micro-method for determining four anti-convulsant drugs by gas-liquid chromatography.
Topics: Animals; Anticonvulsants; Carbon Radioisotopes; Chromatography, Gas; Evaluation Studies as Topic; Horses; Methods; Microchemistry; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Time Factors; Urea | 1973 |
[Hemostasis in epileptic patients treated with anticonvulsant drugs].
Topics: Adolescent; Adult; Aged; Blood Coagulation Disorders; Blood Coagulation Factors; Child; Drug Evaluation; Epilepsy; Female; Hemostasis; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Time Factors | 1973 |
High-dosage intravenous calcium therapy for osteoporosis and osteomalacia in anticonvulsant therapy with hypomobilization.
Topics: Alkaline Phosphatase; Calcium; Child; Child, Preschool; Female; Humans; Infant; Osteomalacia; Osteoporosis; Phenobarbital; Phenytoin; Phosphorus; Rickets | 1974 |
Rickets associated with anticonvulsant medication.
Topics: Alkaline Phosphatase; Calcium; Child, Preschool; Female; Humans; Phenobarbital; Phenytoin; Phosphorus; Primidone; Rickets; Seizures; Vitamin D | 1974 |
Emergency management of the patient with seizures. 1. Generalized status epilepticus.
Topics: Airway Obstruction; Anesthesia, General; Anticonvulsants; Blood Pressure Determination; Blood Specimen Collection; Diazepam; Emergencies; Epilepsy; Humans; Infusions, Parenteral; Monitoring, Physiologic; Paraldehyde; Phenobarbital; Phenytoin; Physical Examination; Pulmonary Ventilation; Wounds and Injuries | 1974 |
The influence of diphenylhydantoin on primidone metabolism.
Topics: Adult; Biotransformation; Chromatography, Gas; Drug Interactions; Enzyme Induction; Epilepsy; Female; Humans; Hydroxylation; Liver; Male; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Regression Analysis | 1974 |
Seizures in newborn infants.
Topics: Birth Injuries; Brain; Calcium; Diazepam; Gluconates; Glucose; Humans; Hypocalcemia; Hypoxia; Infant, Newborn; Infant, Newborn, Diseases; Metabolic Diseases; Metabolism, Inborn Errors; Phenobarbital; Phenytoin; Prognosis; Pyridoxine; Seizures; Substance-Related Disorders | 1974 |
[Letter: Teratogenic hazards in antiepileptic therapy].
Topics: Abnormalities, Drug-Induced; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1974 |
Interaction between doxycycline and barbiturates.
Topics: Adult; Aged; Amobarbital; Barbiturates; Carbamazepine; Doxycycline; Drug Interactions; Enzyme Induction; Female; Half-Life; Humans; Male; Middle Aged; Pentobarbital; Phenobarbital; Phenytoin | 1974 |
Effect of steroidal and nonsteroidal microsomal enzyme inducers on the hepatotoxicity of pyrrolizidine alkaloids in rats.
Topics: Animals; Enzyme Induction; Ethylestrenol; Female; Hepatectomy; Kidney; Liver; Lung; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Pregnenolone Carbonitrile; Prodigiosin; Pyrroles; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Spironolactone | 1974 |
Calcium metabolism in elderly epileptic patients during anticonvulsant therapy.
Topics: Aged; Alkaline Phosphatase; Calcium; Cerebrovascular Disorders; Drug Therapy, Combination; Epilepsy; Female; Humans; Hypocalcemia; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Time Factors | 1974 |
[Fever cramps--medical treatment. Etiology, clinical manifestations, prognosis. Based on a meeting at the Institutt for Farmakoterapi in November 1973].
Topics: Age Factors; Body Temperature; Child, Preschool; Diazepam; Female; Fever; Humans; Infant; Male; Muscle Cramp; Phenobarbital; Phenytoin; Salicylates | 1974 |
Folate metabolism and anticonvulsant therapy.
Topics: Anticonvulsants; Blood-Brain Barrier; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Vitamin B 12 | 1974 |
Crigler-Najjar syndrome: an unusual course with development of neurologic damage at age eighteen.
Topics: Adolescent; Alkaline Phosphatase; Bilirubin; Brain Damage, Chronic; Brain Diseases; Carbon Monoxide; Erythrocyte Aging; Female; Glucuronates; Glutethimide; Humans; Hyperbilirubinemia, Hereditary; Indocyanine Green; Kanamycin; Liver Function Tests; Phenobarbital; Phenytoin; Phototherapy; Plasmapheresis; Protein Binding; Radioisotopes; Renal Dialysis; Salicylamides; Sulfobromophthalein; Syndrome; Transaminases | 1974 |
Infants exposed in utero to antiepileptic drugs. A prospective study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amitriptyline; Amniotic Fluid; Anticonvulsants; Chromatography, Gas; Diazepam; Epilepsy; Ethosuximide; Female; Fetus; Growth Disorders; Humans; Hydantoins; Infant, Newborn; Mass Spectrometry; Mephobarbital; Meprobamate; Milk, Human; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Prochlorperazine; Prospective Studies; Substance Withdrawal Syndrome; Succinimides; Time Factors | 1974 |
Letter: Anticonvulsant drugs and congenital abnormalities.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Epilepsy; Female; Fetus; Fingers; Humans; Infant; Nails, Malformed; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1974 |
Letter: GLC microdetermination of plasma anticonvulsant levels.
Topics: Anticonvulsants; Chromatography, Gas; Ethosuximide; Humans; Methods; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1974 |
Effect of seizures and anticonvulsant agents on hippocampal RNA concentration.
Topics: Anesthesia, General; Animals; Anticonvulsants; Cannabis; Cerebral Cortex; Depression, Chemical; Electric Stimulation; Electroshock; Glucose; Hippocampus; Hyponatremia; Male; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; RNA; Seizures; Time Factors; Trimethadione; Urethane | 1974 |
Effect of anticonvulsant drugs on the number of afferent stimuli needed to cause a hippocampal seizure discharge.
Topics: Animals; Anticonvulsants; Cannabis; Dose-Response Relationship, Drug; Electric Stimulation; Electroshock; Evoked Potentials; Hippocampus; Injections, Intraperitoneal; Neurons, Afferent; Phenobarbital; Phenytoin; Rats; Seizures; Time Factors; Trimethadione | 1974 |
Pharmacology for the pediatrician. Noncompliance contributing to apparent drug failure in status epilepticus.
Topics: Anticonvulsants; Benzodiazepinones; Child; Chlorobenzenes; Diazepam; Epilepsy; Ethosuximide; Female; Humans; Medical Records; Medication Errors; Nitro Compounds; Phenobarbital; Phenytoin; Primidone | 1974 |
Antiepileptic drugs: a current assessment of simultaneous determination of multiple drug therapy by gas liquid chromatography-on column methylation.
Topics: Adult; Anticonvulsants; Autoanalysis; Barbiturates; Buffers; Child; Chromatography, Gas; Humans; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Solvents; Temperature | 1974 |
Decrease in serum diphenylhydantoin levels after withdrawal of phenobarbital in epileptics treated with both drugs.
Topics: Child; Child, Preschool; Chromatography, Gas; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1974 |
Serum levels of diphenylhydantoin and phenobarbital in epileptic children receiving diphenylhydantoin, phenobarbital and-or mysoline.
Topics: Adolescent; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Primidone | 1974 |
Serum anticonvulsant concentrations in epileptic patients with mental symptoms. A preliminary report.
Topics: Adolescent; Adult; Aged; Epilepsy; Female; Humans; Intelligence; Male; Mental Disorders; Middle Aged; Personality Disorders; Phenobarbital; Phenytoin; Primidone; Psychomotor Disorders | 1974 |
Human brain, cerebrospinal fluid, and plasma concentrations of diphenylhydantoin and phenobarbital.
Topics: Adolescent; Adult; Brain Chemistry; Child, Preschool; Chromatography, Gas; Epilepsy, Temporal Lobe; Female; Humans; Male; Nerve Tissue Proteins; Phenobarbital; Phenytoin; Primidone; Protein Binding; Temporal Lobe; Ultrafiltration | 1974 |
New mixed bed column for rapid gas-liquid chromatographic determination of sedatives and Dilantin in serum.
Topics: Amobarbital; Barbiturates; Chromatography, Gas; Evaluation Studies as Topic; Glutethimide; Humans; Methods; Pentobarbital; Phenobarbital; Phenytoin; Secobarbital; Time Factors | 1974 |
[Ethnic differences in serum phenytoin levels].
Topics: Adolescent; Adult; Child; Child, Preschool; Denmark; Epilepsy; Ethnicity; Female; Greenland; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1974 |
Anticonvulsant effects of cannabinoids in mice: drug interactions within cannabinoids and cannabinoid interactions with phenytoin.
Topics: Animals; Cannabis; Depression, Chemical; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electroshock; Herb-Drug Interactions; Injections, Intraperitoneal; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Phytotherapy; Seizures; Stimulation, Chemical | 1974 |
Anticonvulsant properties of cannabidiol.
Topics: Animals; Anticonvulsants; Body Temperature; Cannabis; Cold Temperature; Dronabinol; Drug Interactions; Drug Synergism; Electroshock; Hindlimb; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Phenobarbital; Phenytoin; Temperature; Time Factors | 1974 |
Erythrocyte uptake and plasma binding of diphenylhydantoin.
Topics: Carbon Radioisotopes; Dialysis; Erythrocytes; Ethosuximide; Female; Hematocrit; Humans; Hydroxylation; Liver Cirrhosis; Male; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Protein Binding; Sulfamethoxypyridazine; Time Factors; Uremia | 1974 |
Isolation of 1,4-androstadiene-3,17-dione from urine of an epileptic boy.
Topics: Adolescent; Androstenes; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Circular Dichroism; Epilepsy; Humans; Ketosteroids; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Phenobarbital; Phenytoin; Puberty; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1974 |
Phenytoin inhibition of parathyroid hormone induced bone resorption in vitro.
Topics: Animals; Bone Resorption; Calcium; Calcium Radioisotopes; Culture Media; Culture Techniques; Hypocalcemia; Mice; Parathyroid Hormone; Phenobarbital; Phenytoin; Proteins | 1974 |
Stress convulsions.
Topics: Adolescent; Adult; Affect; Age Factors; Child; Electroencephalography; Epilepsy; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Physical Exertion; Prognosis; Sex Factors; Sleep Deprivation; Stress, Physiological; Stress, Psychological | 1974 |
Prolonged twilight state and automatisms: a case report.
Topics: Adult; Automatism; Dissociative Disorders; Electroencephalography; Epilepsy, Temporal Lobe; Humans; Male; Phenobarbital; Phenytoin; Stereotyped Behavior; Temporal Lobe | 1974 |
Delivery of anticonvulsant drug therapy in epileptic patients assessed by plasma level analyses.
Topics: Adolescent; Adult; Child; Chromatography, Gas; Drug Therapy; Electroencephalography; Epilepsy; Humans; Institutional Practice; Middle Aged; Phenobarbital; Phenytoin; Primidone; Recurrence; Time Factors | 1974 |
The influence of aging on the activity of anticonvulsant drugs.
Topics: Acetazolamide; Aging; Animals; Blood-Brain Barrier; Carbon Dioxide; Carbonic Anhydrases; Cerebral Cortex; Mice; Oxygen Consumption; Phenobarbital; Phenytoin; Rats; Sulfanilamides | 1965 |
[Ethosuximide in treatment of petit mal epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Trimethadione | 1965 |
[Treatment of epilepsy with tegretol (5-carbamyl-5H-dibenzo (b,f) azepine)].
Topics: Adolescent; Adult; Anticonvulsants; Azepines; Child; Chlordiazepoxide; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Male; Phenobarbital; Phenytoin | 1965 |
Petit mal status in adults.
Topics: Adult; Anticonvulsants; Catatonia; Chlordiazepoxide; Diagnosis, Differential; Electroencephalography; Epilepsy, Absence; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Pyrrolidinones | 1968 |
Treatment of grand mal epilepsy: phenobarbital versus diphenylhydantoin sodium.
Topics: Adolescent; Epilepsy, Tonic-Clonic; Female; Gingival Hyperplasia; Humans; Hypertrichosis; Infant; Phenobarbital; Phenytoin | 1968 |
Hydantoin-induced pseudo-pseudolymphoma.
Topics: Epilepsy, Tonic-Clonic; Hodgkin Disease; Humans; Hydantoins; Lymph Nodes; Lymphadenitis; Lymphatic Diseases; Male; Middle Aged; Phenobarbital; Phenytoin | 1968 |
[The treatment of epilepsy with falepsin. A report of the clinical experience gained].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle Aged; Norepinephrine; Phenobarbital; Phenytoin | 1968 |
The hyperexcitable neuron as a model for the laboratory analysis of anticonvulsant drugs.
Topics: Acetazolamide; Action Potentials; Aluminum; Animals; Behavior, Animal; Cats; Cerebral Cortex; Electroencephalography; Haplorhini; Hydroxides; Models, Biological; Neurons; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Time Factors; Trimethadione | 1969 |
The anticonvulsant effects of phenobarbital, diphenylhydantoin and two benzodiazepines in the baboon, Papio papio.
Topics: Animals; Anticonvulsants; Benzazepines; Diazepam; Disease Models, Animal; Electrodes; Electroencephalography; Female; Haplorhini; Light; Male; Motor Activity; Phenobarbital; Phenytoin; Seizures | 1970 |
[Results of treatment of epilepsy in children up to 14 years of age].
Topics: Adolescent; Age Factors; Barbiturates; Child; Child, Preschool; Diazepam; Drug Synergism; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Infant; Phenobarbital; Phenytoin; Primidone | 1971 |
Relationship between paroxysmal atrial tachycardia and paroxysmal cerebral discharges.
Topics: Anticonvulsants; Child, Preschool; Electrocardiography; Electroencephalography; Epilepsy; Humans; Hydantoins; Male; Phenobarbital; Phenytoin; Tachycardia; Tachycardia, Paroxysmal | 1972 |
Further observations on the interactions between phenobarbital and diphenylhydantoin during chronic treatment in the rat.
Topics: Administration, Oral; Animals; Brain; Chemical Phenomena; Chemistry; Electroshock; Female; Injections, Intraperitoneal; Kinetics; Metabolism; Phenobarbital; Phenytoin; Rats; Seizures; Time Factors | 1972 |
Folate deficiency and anticonvulsant drugs.
Topics: Animals; Enzyme Induction; Female; Folic Acid; Folic Acid Deficiency; Liver; Male; Oxidoreductases; Phenobarbital; Phenytoin; Rats; Transferases | 1972 |
Influence of certain anticonvulsants on the concentration of -aminobutyric acid in the cerebral hemispheres of mice.
Topics: Aminobutyrates; Animals; Anticonvulsants; Barbiturates; Brain Chemistry; Drug Antagonism; Drug Interactions; Hydantoins; Isoniazid; Male; Mice; Phenobarbital; Phenytoin; Primidone; Stimulation, Chemical | 1972 |
Coarse facies, calvarial thickening and hyperphosphatasia associated with long-term anticonvulsant therapy.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Child; Diazepam; Ethosuximide; Facial Expression; Gingival Hyperplasia; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Skull; Time Factors | 1972 |
An isothermal GLC determination of the plasma levels of carbamazepine, diphenylhydantoin, phenobarbitone and primidone.
Topics: Benzyl Compounds; Carbamazepine; Chloroform; Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Phthalic Acids; Primidone; Solubility; Spectrophotometry; Ultraviolet Rays | 1972 |
Effect of various steroids and nonsteroidal microsomal enzyme inducers upon propoxyphene intoxication.
Topics: Animals; Dextropropoxyphene; Enzyme Induction; Estradiol; Female; Phenobarbital; Phenytoin; Poisoning; Prednisolone; Rats; Thyroxine; Triamcinolone | 1972 |
Phocomelia.
Topics: Abnormalities, Drug-Induced; Ectromelia; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy | 1972 |
Altered calcium metabolism due to anticonvulsant drugs.
Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Arthrography; Calcium; Calcium Metabolism Disorders; Child; Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Phosphates; Primidone; Succinimides; Vitamin D | 1972 |
Long-term administration of antiepileptic drugs and the development of rickets.
Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Diazepam; Ethosuximide; Female; Gluconates; Humans; Infant; Mephobarbital; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone; Radiography; Rickets; Seizures; Time Factors; Trimethadione; Vitamin D | 1972 |
Antiepileptic drug concentrations in plasma. Clinical evaluation of 321 estimations in 237 unselected patients.
Topics: Carbamazepine; Chromatography, Gas; Chromatography, Thin Layer; Epilepsy; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1972 |
Anticonvulsant hypocalcaemia.
Topics: Calcium; Epilepsy; Humans; Hypocalcemia; Phenobarbital; Phenytoin | 1972 |
Fluorometric assay of diphenylhydantoin in plasma or whole blood.
Topics: Anticonvulsants; Humans; Methods; Oxidation-Reduction; Phenobarbital; Phenols; Phenytoin; Potassium Permanganate; Spectrometry, Fluorescence; Sulfuric Acids | 1972 |
Treatment of epilepsy in the light of determinations of the blood levels of anticonvulsants.
Topics: Adult; Child; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1972 |
Two dimensional immunoelectrophoresis of human serum proteins for the investigation of protein drugs.
Topics: Aspirin; Blood Proteins; Carbon Isotopes; Humans; Immunoelectrophoresis; Iodine Isotopes; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Thyroxine | 1972 |
Determination of phenylbutazone in plasma.
Topics: Animals; Injections, Intravenous; Male; Methods; Oxidation-Reduction; Phenobarbital; Phenylbutazone; Phenytoin; Potassium Permanganate; Rats; Salicylates; Spectrophotometry; Spectrum Analysis; Sulfadiazine; Time Factors; Ultraviolet Rays; Warfarin | 1972 |
Diphenylhydantoin and epilepsy management.
Topics: Administration, Oral; Epilepsy; Humans; Injections, Intramuscular; Injections, Intravenous; Phenobarbital; Phenytoin | 1972 |
5,5'-Diphenyl-2-thiohydantoin (DPTH): an inducer of microsomal drug-metabolizing enzymes.
Topics: Animals; Cytochromes; Electron Transport; Endoplasmic Reticulum; Enzyme Induction; Hexobarbital; Liver; Male; Mice; Mice, Inbred Strains; Microscopy, Electron; Microsomes, Liver; Organ Size; Phenobarbital; Phenytoin; Proteins; Rats; Rats, Inbred Strains; Sleep; Sulfides; Time Factors | 1972 |
Drug interactions. 3. Therapeutic implications of enzyme induction.
Topics: Age Factors; Child; Child, Preschool; Drug Interactions; Drug Synergism; Enzyme Induction; Epilepsy; Humans; Intellectual Disability; Microsomes; Microsomes, Liver; Phenobarbital; Phenytoin | 1972 |
Rapid routine determination of some anti-epileptic drugs in serum by gas chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin | 1972 |
GLC determination of carbamazepine in plasma.
Topics: Benzocycloheptenes; Carbamates; Carbamazepine; Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1972 |
Trichopoliodystrophy. I. Report of a case and biochemical studies.
Topics: Amino Acids; Brain Chemistry; Brain Diseases; Cerebellum; Cerebral Cortex; Cerebrosides; Cholesterol; Electroencephalography; Glycogen; Growth Disorders; Hair; Humans; Infant; Male; Nerve Degeneration; Pedigree; Phenobarbital; Phenytoin; Phospholipids; Plasmalogens; Seizures; Ubiquinone; Vitamin E | 1972 |
[Speech disorders in children with cerebral convulsions].
Topics: Adolescent; Barbiturates; Carbamazepine; Drug Hypersensitivity; Electroencephalography; Epilepsy; Ethosuximide; Humans; Male; Phenobarbital; Phenytoin; Primidone; Speech Disorders; Speech Therapy; Verbal Behavior | 1972 |
[Experimental studies on the mechanism of digitalis and several antiarrhythmic agents--a consideration on roles of the central nervous system].
Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Brain; Cerebral Cortex; Digitalis Glycosides; Electrocardiography; Electroencephalography; Hypothalamus; Mesencephalon; Phenobarbital; Phenytoin; Procainamide; Propranolol; Rabbits; Thalamus | 1972 |
Seven-year "cure" of lung cancer with metastasis to the brain.
Topics: Adenocarcinoma; Brain Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Phenobarbital; Phenytoin; Time Factors | 1972 |
Status epilepticus as a complication of intrathecal fluorescein. Case report.
Topics: Aged; Cerebrospinal Fluid Rhinorrhea; Contrast Media; Epilepsy; Fluoresceins; Glucocorticoids; Humans; Injections, Spinal; Male; Meningitis; Phenobarbital; Phenytoin; Radiography; Spinal Puncture | 1972 |
Febrile convulsions in early childhood.
Topics: Child, Preschool; Epilepsy; Fever; Hospitalization; Humans; Phenobarbital; Phenytoin; Seizures | 1972 |
Checking compliance of epileptic patients.
Topics: Adolescent; Anticonvulsants; Epilepsy; Humans; Phenobarbital; Phenytoin | 1972 |
[Neurotoxicity of drugs].
Topics: Arsenic; Drug-Related Side Effects and Adverse Reactions; Humans; Nervous System Diseases; Nitrofurantoin; Penicillins; Phenobarbital; Phenytoin; Sulfonamides; Vincristine | 1972 |
Rickets following anticonvulsant therapy.
Topics: Child, Preschool; Humans; Infant; Male; Phenobarbital; Phenytoin; Primidone; Rickets; Vitamin D | 1972 |
Effect of microsomal enzyme inducing drugs on DDt and dieldrin elimination from cows.
Topics: Animals; Cattle; Cattle Diseases; DDT; Dieldrin; Diet Therapy; Enzymes; Fats; Microsomes, Liver; Milk; Pesticides; Phenobarbital; Phenytoin; Poisoning | 1971 |
The effects of some stimulators (inducers) of hepatic microsomal drug-metabolizing enzyme activity on substrate-induced difference spectra in rat liver microsomes.
Topics: Aniline Compounds; Animals; Benzphetamine; Carbon Isotopes; DDT; Enzyme Induction; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Spectrophotometry | 1971 |
Concurrent administration of phenobarbital and diphenylhydantoin: lack of an interference effect.
Topics: Adolescent; Adult; Child; Chronic Disease; Drug Antagonism; Epilepsy; Humans; Phenobarbital; Phenothiazines; Phenytoin | 1971 |
[Familial Q-T prolongation syndrome characterised by syncopal attacks].
Topics: Adult; Electrocardiography; Electroencephalography; Female; Heart Diseases; Humans; Male; Phenobarbital; Phenytoin; Syncope | 1971 |
Diphenylhydantoin (Dilatin) and phenobarbital blood levels in epileptic children.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Chromatography, Gas; Electroencephalography; Epilepsy; Female; Humans; Infant; Male; Phenobarbital; Phenytoin | 1971 |
[Changes of drug effects caused by their metabolism in the liver].
Topics: Aminopyrine; Animals; Cytochromes; Dogs; Drug Stability; Endoplasmic Reticulum; Female; Fetus; Hexobarbital; Humans; Liver; Male; Metabolism; Mice; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Pregnancy; Rabbits; Rats; Thiopental | 1971 |
Anticonvulsants and DDT residues.
Topics: Adult; DDT; Environmental Exposure; Humans; Hydrocarbons, Halogenated; Male; Phenobarbital; Phenytoin | 1971 |
Accelerated peritoneal dialysis of barbiturates, diphenylhydantoin, and salicylate.
Topics: Amobarbital; Animals; Barbiturates; Blood Proteins; Carbon Isotopes; Chemical Phenomena; Chemistry; Dialysis; Drug Synergism; Male; ortho-Aminobenzoates; Peritoneal Dialysis; Phenobarbital; Phenytoin; Protein Binding; Rabbits; Salicylates | 1971 |
[Treatment of epilepsy in the light of the determination of the anticonvulsant blood level].
Topics: Administration, Oral; Age Factors; Anticonvulsants; Drug Synergism; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Sex Factors; Time Factors | 1971 |
Non-equivalent preparations of the same drug.
Topics: Chloramphenicol; Dosage Forms; Humans; Nitrofurantoin; Oxytetracycline; Pharmaceutical Preparations; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Tetracycline; Therapeutic Equivalency; Tolbutamide; Warfarin | 1971 |
Variations of serum diphenylhydantoin concentrations in epileptic out-patients.
Topics: Adolescent; Adult; Aged; Blood Proteins; Body Weight; Drug Synergism; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding | 1971 |
[Clinical and pharmacodynamic correlations of phenobarbital (PB) and diphenylhydantoin (DPH) in the treatment of infantile epilepsy].
Topics: Adolescent; Child; Child, Preschool; Epilepsy; Humans; Infant; Phenobarbital; Phenytoin | 1971 |
Bone density in patients receiving long-term anticonvulsant therapy.
Topics: Absorptiometry, Photon; Adult; Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Epilepsy; Female; Forearm; Heel; Humans; Iodine Radioisotopes; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone | 1971 |
Effects of phenobarbital or SKF 525A pretreatment on diphenylhydantoin disposition in pregnant mice.
Topics: Abnormalities, Drug-Induced; Adipose Tissue; Amniotic Fluid; Animals; Brain Chemistry; Carbon Isotopes; Chromatography, Thin Layer; Feces; Female; Fetus; Injections, Intraperitoneal; Liver; Mice; Mice, Inbred Strains; Muscles; Phenobarbital; Phenytoin; Placenta; Pregnancy; Pregnancy, Animal; Proadifen; Time Factors | 1971 |
Folic acid concentrations in cerebrospinal fluid in relation to anticonvulsant drugs and cerebral atrophy.
Topics: Adult; Anticonvulsants; Atrophy; Brain Diseases; Epilepsy; Female; Folic Acid; Humans; Male; Mental Disorders; Middle Aged; Phenobarbital; Phenytoin; Pneumoencephalography | 1971 |
Age differences in drug binding by plasma proteins: studies on human foetuses, neonates and adults.
Topics: Adult; Age Factors; Aging; Ampicillin; Azides; Bilirubin; Blood Proteins; Dialysis; Female; Fetus; Freezing; Gestational Age; Humans; Hydrogen-Ion Concentration; Hyperbilirubinemia; Infant, Newborn; Maternal-Fetal Exchange; Penicillin G; Phenobarbital; Phenytoin; Pregnancy; Protein Binding; Sulfur Isotopes | 1971 |
Folate metabolism in epileptic and psychiatric patients.
Topics: Adult; Antidepressive Agents; Epilepsy; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Mental Disorders; Middle Aged; Phenobarbital; Phenothiazines; Phenytoin; Vitamin B 12 | 1971 |
Variation in response to anticonvulsants in a group of epileptic patients.
Topics: Epilepsy, Temporal Lobe; Female; Humans; Male; Mental Disorders; Phenobarbital; Phenytoin; Primidone | 1971 |
Pharmacological and biochemical studies on 2-amino-4-phenylsulphonylbenzenesulphonamide (NSD 3004): a new sulphonamide with anticonvulsant and carbonic anhydrase inhibitory properties.
Topics: Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Diuresis; Electroshock; Enzyme Activation; Lethal Dose 50; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Seizures; Strychnine; Sulfonamides | 1971 |
Treatment of common uncomplicated seizure disorders in children.
Topics: Anticonvulsants; Child; Child, Preschool; Humans; Infant; Phenobarbital; Phenytoin; Seizures | 1971 |
Effects of convulsions and anticonvulsants on blood sugar in rabbits.
Topics: Animals; Blood Glucose; Electric Stimulation; Electroshock; Gallamine Triethiodide; Phenobarbital; Phenytoin; Rabbits; Seizures; Spectrophotometry; Stress, Physiological | 1965 |
Musicogenic epilepsy. A case report.
Topics: Adult; Chlordiazepoxide; Electroencephalography; Emotions; Epilepsy; Epilepsy, Temporal Lobe; Hearing; Humans; Hypnosis; Male; Music; Phenobarbital; Phenytoin; Placebos; Prognosis; Reflex | 1965 |
Anticonvulsant therapy, folic acid and vitamin B12 metabolism and mental symptoms.
Topics: Adult; Anemia, Macrocytic; Female; Folic Acid Deficiency; Humans; Male; Mental Disorders; Middle Aged; Phenobarbital; Phenytoin; Primidone; Seizures; Vitamin B 12 Deficiency | 1966 |
[Contribution to the pathogenesis of gingival hypertrophy due to diphenylhydantoin in experiments on animals].
Topics: Anemia; Animals; Drug Synergism; FIGLU Test; Folic Acid; Gingival Hypertrophy; Phenobarbital; Phenytoin; Rats | 1968 |
Effects of antiepileptic drugs on electrically-induced responses of acutely and chronically isolated cerebral cortex of the cat.
Topics: Action Potentials; Animals; Anticonvulsants; Cats; Cerebral Cortex; Denervation; Depression, Chemical; Electric Stimulation; Models, Biological; Phenobarbital; Phenytoin; Procaine; Seizures; Thiopental | 1968 |
The effect of diphenylhydantoin and phenobarbital on the liver of the pig.
Topics: Acid Phosphatase; Animals; Liver; Lysosomes; Oxidoreductases; Phenobarbital; Phenytoin; Swine; Tetrazolium Salts | 1969 |
Influence of ethylphenacemide on serum levels of other anti-epileptic drugs.
Topics: Adolescent; Adult; Benzazepines; Butyrates; Chromatography, Thin Layer; Colorimetry; Drug Synergism; Humans; Male; Phenobarbital; Phenytoin; Primidone; Urea | 1970 |
A clinical study of serum primidone levels.
Topics: Administration, Oral; Adolescent; Adult; Biotransformation; Child; Child, Preschool; Chromatography, Gas; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1970 |
Management of hemiplegic child. Role of neurologist.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Hemiplegia; Humans; Infant; Infant, Newborn; Phenobarbital; Phenytoin; Primidone | 1971 |
Interactions between digitoxin and other drugs in vitro and in vivo.
Topics: Binding Sites; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Clofibrate; Digitoxin; Digoxin; Drug Antagonism; Enzyme Induction; Erythrocytes; Humans; Microsomes, Liver; Phenobarbital; Phenylbutazone; Phenytoin; Protein Binding; Radioisotopes; Rubidium; Serum Albumin; Sulfadimethoxine; Tolbutamide; Tritium; Warfarin | 1971 |
Interaction between phenobarbital and diphenylhydantoin in animals and in epileptic patients.
Topics: Adolescent; Adult; Animals; Brain; Brain Chemistry; Child; Child, Preschool; Chromatography, Gas; Epilepsy; Female; Half-Life; Humans; Infant; Kinetics; Male; Metabolism; Mice; Middle Aged; Phenobarbital; Phenytoin; Rats; Time Factors | 1971 |
Anticonvulsant drugs and folic acid in young mentally retarded epileptic patients. A study of serum folate, fit frequency and I.Q.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Folic Acid; Humans; Intellectual Disability; Intelligence Tests; Male; Phenobarbital; Phenytoin; Primidone; Prognosis | 1971 |
m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anticonvulsants; Atropine; Azoles; Brain; Chlordiazepoxide; Chlorpromazine; Citrates; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Drug Synergism; Kidney; Lysergic Acid Diethylamide; Male; Methyldopa; Mice; Morphine; Nialamide; Norepinephrine; Pargyline; Phenobarbital; Phenytoin; Reserpine; Seizures; Serotonin; Strychnine; Tetrabenazine; Trimethadione; Tyrosine; Urea | 1967 |
Focal spike discharges in children, a longitudinal study.
Topics: Adolescent; Aging; Central Nervous System Diseases; Cerebral Palsy; Cerebral Ventriculography; Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Humans; Infant; Infant, Newborn; Male; Phenobarbital; Phenytoin; Prognosis; Psychological Tests | 1966 |
A simple method to measure central antinocotinic activity.
Topics: Animals; Atropine; Brain; Female; Infusions, Parenteral; Injections; Male; Methods; Mice; Nicotine; Phenobarbital; Phenytoin; Seizures | 1969 |
Dieldrin: studies in a poisoned child.
Topics: Accidents, Home; Adipose Tissue; Autopsy; Blood Proteins; Brain; Child, Preschool; Dieldrin; Electroencephalography; Female; Humans; Liver Function Tests; Male; Models, Biological; Muscles; Phenobarbital; Phenytoin; Protein Binding; Seizures; Time Factors | 1969 |
Intolerance to diphenylhydantoin in five cases of Vogt-Spielmeyer disease.
Topics: Ataxia; Brain; Humans; L-Lactate Dehydrogenase; Lipidoses; Phenobarbital; Phenytoin; Primidone; Seizures | 1969 |
Studies on the glucaric acid pathway in the metabolism of D-glucuronic acid in mammals. V. Stimulatory effect of diphenylhydantoin and phenobarbital on the D-glucaric acid synthesis in man.
Topics: Adipates; Epilepsy; Hexoses; Humans; Phenobarbital; Phenytoin; Stimulation, Chemical | 1969 |
Central effects of diphenylhydantoin (dilantin) in epileptic oligophrenics during phenobarbital-primidone withdrawal, sodium bicarbonate, and ammonium chloride administration.
Topics: Adolescent; Adult; Ammonium Chloride; Bicarbonates; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Intellectual Disability; Lipidoses; Male; Phenobarbital; Phenytoin; Primidone; Sodium | 1969 |
[Introduction of mass psychology of animals to pharmacology. 2. New screening method of drugs acting on the central nervous system].
Topics: Aminobutyrates; Amphetamine; Animals; Anticonvulsants; Behavior, Animal; Carbamates; Chlordiazepoxide; Chlorpromazine; Diphenhydramine; Imidazoles; Imipramine; Male; Mice; Phenobarbital; Phenytoin; Reserpine; Tranquilizing Agents | 1969 |
Central effect of diphenylhydantoin (Dilantin) in epileptic oligophrenics during phenobarbital-primidone withdrawal, sodium bicarbonate, and ammonium chloride administration.
Topics: Adolescent; Adult; Ammonium Chloride; Bicarbonates; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Intellectual Disability; Lipidoses; Male; Phenobarbital; Phenytoin; Primidone; Sodium | 1969 |
Febrile seizures: to treat or not to treat.
Topics: Acute Disease; Age Factors; Anticonvulsants; Child; Child, Preschool; Fever; Humans; Infant; Phenobarbital; Phenytoin; Seizures | 1970 |
Concurrent assay of phenobarbital and diphenylhydantoin in plasma by vapor-phase chromatography.
Topics: Chloroform; Chromatography, Gas; Humans; Hydrogen-Ion Concentration; Methods; Phenobarbital; Phenytoin; Primidone; Solubility; Time Factors | 1970 |
Extreme elevations of cerebrospinal fluid protein. Association with hypernatremic dehydration.
Topics: Blood Proteins; Blood-Brain Barrier; Central Nervous System Diseases; Cerebrospinal Fluid Proteins; Dehydration; Diarrhea; Female; Humans; Hypernatremia; Infant; Kanamycin; Lumbosacral Region; Male; Penicillins; Phenobarbital; Phenytoin; Seizures; Sodium Chloride; Spinal Puncture | 1970 |
Enhancement by phenobarbital and diphenylhydantoin of carbon monoxide production in normal man.
Topics: Adult; Bilirubin; Carbon Monoxide; Heme; Humans; Liver; Male; Phenobarbital; Phenytoin | 1970 |
Pharmacologic interactions of albutoin with other anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Drug Synergism; Electroshock; Hydantoins; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Trimethadione | 1970 |
Effect of parathion on liver microsomal enzyme activites induced by organochlorine pesticides and drugs in female rats.
Topics: Animals; Azo Compounds; Chlordan; DDT; Dimenhydrinate; Female; Hydrocarbons, Halogenated; Microsomes, Liver; Naphthalenes; Oxidoreductases; Paraldehyde; Parathion; Phenobarbital; Phenytoin; Rats; Trimethadione | 1970 |
[Phenobarbital and diphenylhydantoin in the plasma and phenobarbital in the cerebrospinal fluid. I. Studies on the concurrent determination of phenobarbital and diphenylhydantoin in the plasma by ultraviolet spectrophotometry and its clinical application]
Topics: Age Factors; Child; Child, Preschool; Female; Humans; Male; Phenobarbital; Phenytoin; Spectrophotometry; Ultraviolet Rays | 1970 |
A new method for treatment of barbiturate dependence.
Topics: Barbiturates; Chlordiazepoxide; Diazepam; Heroin; Humans; Meprobamate; Pentobarbital; Phenobarbital; Phenytoin; Secobarbital; Substance Withdrawal Syndrome; Substance-Related Disorders | 1970 |
[Case of tonic seizure].
Topics: Adult; Arm; Benzazepines; Diphenhydramine; Electroencephalography; Epilepsy; Humans; Injections, Intravenous; Leg; Male; Phenobarbital; Phenytoin; Seizures | 1970 |
Stabilization of excitable membrane by chronic administration of diphenylhydantoin.
Topics: Action Potentials; Animals; Electric Stimulation; Female; Male; Membrane Potentials; Myelin Sheath; Neural Conduction; Phenobarbital; Phenytoin; Rabbits; Vagus Nerve | 1970 |
Disturbance of calcium metabolism by anticonvulsant drugs.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Anticonvulsants; Calcium Metabolism Disorders; Enzyme Induction; Epilepsy; Female; Humans; Hypocalcemia; Isoenzymes; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Phosphorus; Primidone; Vitamin D; Vitamin D Deficiency | 1970 |
The clinical significance of microsomal enzyme induction in the therapy of epileptic patients.
Topics: Adult; Chromatography; Enzyme Induction; Epilepsy; Female; Humans; Male; Microsomes, Liver; Phenobarbital; Phenytoin | 1970 |
Micro-determination of serum phenobarbitone and diphenylhydantoin by gas-liquid chromatography.
Topics: Adult; Anticonvulsants; Chromatography, Gas; Epilepsy; Humans; Indicators and Reagents; Methods; Microchemistry; Phenobarbital; Phenytoin | 1970 |
Anticonvulsant drugs and self-stimulation rates in rats.
Topics: Acetazolamide; Animals; Chlordiazepoxide; Electrodes; Male; Meprobamate; Pentobarbital; Pentylenetetrazole; Phenobarbital; Phenytoin; Placebos; Rats; Seizures; Self Stimulation | 1970 |
Effect of phenobarbital and SKF 525A pretreatment on diphenylhydantoin teratogenicity in mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Depression, Chemical; Drug Synergism; Female; Fetal Diseases; Fetus; Mice; Phenobarbital; Phenytoin; Pregnancy; Pregnancy, Animal; Proadifen; Stimulation, Chemical | 1970 |
Drug and environmental effects on DDT residues in human blood.
Topics: Adult; DDT; Environment; Female; Humans; Intellectual Disability; Male; Phenobarbital; Phenytoin; Racial Groups | 1970 |
A study of the excitatory effects of barbiturates.
Topics: Animals; Anticonvulsants; Barbiturates; Chemical Phenomena; Chemistry; Injections, Intravenous; Male; Mice; Pentobarbital; Phenobarbital; Phenytoin; Seizures; Stereoisomerism; Trimethadione | 1970 |
Quantitative estimation of diphenylhydantoin, primidone and phenobarbital in plasma by gas-liquid chromatography.
Topics: Aniline Compounds; Chromatography, Gas; Hot Temperature; Humans; Methods; Methylation; Phenobarbital; Phenytoin; Primidone | 1970 |
New developments in anticonvulsant therapy.
Topics: Anticonvulsants; Epilepsy; Humans; Phenobarbital; Phenytoin | 1970 |
The distribution of plasma phenytoin levels in epileptic patients.
Topics: Adult; Drug Tolerance; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1970 |
[Anticonvulsant action of imipramine and imitriptyline associated with phenobarbital, phenytoin and diazepam].
Topics: Amitriptyline; Animals; Anticonvulsants; Diazepam; Electroshock; Imipramine; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures | 1970 |
The importance of gastric lavage in the treatment of poisoning.
Topics: Amobarbital; Barbiturates; Chloroform; Chromatography, Thin Layer; Forensic Medicine; Gastric Lavage; Humans; Phenobarbital; Phenytoin; Poisoning; Primidone; Secobarbital | 1970 |
P henobarbital-Dilantin treatment of the intrauterine patient.
Topics: Enzyme Induction; Epilepsy; Erythroblastosis, Fetal; Female; Fetal Diseases; Humans; Infant, Newborn; Infant, Premature, Diseases; Jaundice, Neonatal; Liver; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1970 |
Diphenylhydantoin-induced difference spectra with rat-liver microsomes.
Topics: Animals; Benzphetamine; Chlordan; DDT; Drug Interactions; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Spectrum Analysis | 1970 |
A rapid high resolution chromatographic method for serum barbiturates: instant thin-layer chromatography.
Topics: Amobarbital; Ascitic Fluid; Barbiturates; Chromatography, Thin Layer; Humans; Mathematics; Methods; Pentobarbital; Phenobarbital; Phenytoin; Secobarbital | 1970 |
Drugs and the liver.
Topics: Bilirubin; Cushing Syndrome; DDT; Enzyme Induction; Ethanol; Female; Humans; Hyperbilirubinemia; Infant, Newborn; Jaundice, Neonatal; Liver; Male; Phenobarbital; Phenytoin; Porphyrins; Pregnancy; Transferases; Warfarin | 1970 |
Effects of various drugs on the uterotropic response to mestranol and norethynodrel in the rat.
Topics: Aminosalicylic Acids; Animals; Chlorpromazine; Drug Synergism; Female; Imipramine; Mestranol; Norethynodrel; Organ Size; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Rats; Scopolamine; Tolbutamide; Uterus | 1971 |
Synthesis and anticonvulsant activity of substituted 2-thioquinazolin-4-ones. I. Preliminary studies.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Electroshock; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Quinazolines; Seizures | 1971 |
Maternal folate deficiency and pregnancy wastage. IV. Effects of folic acid supplements, anticonvulsants, and oral contraceptives.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anemia, Macrocytic; Anemia, Sickle Cell; Anemia, Sideroblastic; Anticonvulsants; Birth Weight; Contraceptives, Oral; Drug Antagonism; Epilepsy; Female; Fetus; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Hemoglobinometry; Humans; Hypertension; Infant Mortality; Infant, Newborn; Infant, Premature; Iron; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1971 |
Seizures and fever.
Topics: Acetaminophen; Acidosis, Respiratory; Age Factors; Alkalosis, Respiratory; Aspirin; Brain Diseases; Child, Preschool; Electroencephalography; Fever; Gastrointestinal Diseases; Humans; Hyponatremia; Infant; Phenobarbital; Phenytoin; Prognosis; Respiratory Tract Infections; Seizures; Syncope | 1971 |
A comparison of the anticonvulsant properties of 2-diethylaminopento-4-ynoyl-2',6'-xylidide (WY 21745) with lignocaine, phenytoin, phenobarbitone and trimethadione.
Topics: Anesthetics, Local; Animals; Anticonvulsants; Drug Antagonism; Electroshock; Lethal Dose 50; Lidocaine; Mice; Oxazoles; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Trimethadione | 1971 |
Rickets and anticonvulsant therapy in children: a roentgenologic investigation.
Topics: Adolescent; Anticonvulsants; Benzazepines; Child; Dextroamphetamine; Diazepam; Ethosuximide; Female; Hand; Humans; Knee; Male; Methylphenidate; Phenobarbital; Phenytoin; Primidone; Radiography; Rickets; Thioridazine; Time Factors | 1971 |
[Congenital abnormalities, cleft lip and cleft palate in particular, in children of epileptic mothers].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Cleft Lip; Cleft Palate; Epilepsy; Female; Humans; Infant, Newborn; Parity; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone | 1971 |
A teething lotion resulting in the misdiagnosis of diphenylhydantoin administration.
Topics: Blood Chemical Analysis; Child Abuse; Condiments; Humans; Infant; Male; Methods; Phenobarbital; Phenytoin; Solutions; Substance-Related Disorders; Tooth Eruption; Vitamins | 1971 |
Diphenylhydantoin metabolism by rat liver microsomes and some of the effects of drug or chemical pretreatment on diphenylhydantoin metabolism by rat liver microsomal preparations.
Topics: Animals; Chlordan; DDT; Enzyme Induction; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Spectrophotometry; Stimulation, Chemical | 1971 |
Dialysis of drugs against activated charcoal.
Topics: Adsorption; Amitriptyline; Aspirin; Charcoal; Chlordiazepoxide; Chloroquine; Dextroamphetamine; Dextropropoxyphene; Dialysis; Diazepam; Glutethimide; Meprobamate; Methaqualone; Models, Biological; Pentazocine; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Salicylates; Secobarbital; Time Factors | 1971 |
Anticonvulsant drugs and brain glucose.
Topics: Acetazolamide; Animals; Anticonvulsants; Blood Glucose; Brain Chemistry; Ethosuximide; Glucose; Guinea Pigs; In Vitro Techniques; Mathematics; Mice; Oligosaccharides; Phenobarbital; Phenytoin; Sodium; Xylose | 1971 |
Gas chromatographic assay of underivatized 5,5-diphenylhydantoin (dilantin) in plasma extracts.
Topics: Carbamazepine; Chloroform; Chromatography, Gas; Coma; Epilepsy; Humans; Hydrogen-Ion Concentration; Methods; Phenobarbital; Phenytoin; Primidone | 1971 |
[Correlation between the prescribed dose of anti-epileptic agents and the blood levels measured].
Topics: Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone | 1971 |
[Eye hypotension due to anticonvulsants in rabbits].
Topics: Animals; Anticonvulsants; Female; Intraocular Pressure; Male; Oxazoles; Phenobarbital; Phenytoin; Rabbits; Trimethadione | 1967 |
Studies on electrically induced-seizures and their antagonism by anticonvulsants during neonatal development in the mouse.
Topics: Acetazolamide; Animals; Animals, Newborn; Anticonvulsants; Electric Stimulation; Ethosuximide; Mice; Phenobarbital; Phenytoin; Seizures; Trimethadione | 1967 |
Experimental study on combined treatment with phenobarbitone and dipenylhydantoin.
Topics: Animals; Dogs; Phenobarbital; Phenytoin | 1967 |
Studies on the anticonvulsant properties of some benzodiazepines. (Chlordiazepoxide, diazepam, oxazepam).
Topics: Action Potentials; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Electroencephalography; Female; Male; Morphine; Nicotine; Oxazepam; Phenobarbital; Phenytoin; Rabbits; Seizures; Strychnine | 1967 |
Subacute encephalitis. A case report.
Topics: Adolescent; Brain; Diagnosis, Differential; Diazepam; Electroencephalography; Electromyography; Encephalitis; Humans; Male; Movement Disorders; Phenobarbital; Phenytoin; Subacute Sclerosing Panencephalitis | 1967 |
Epileptic seizures in non-embolic cerebral infarction.
Topics: Cerebrovascular Disorders; Epilepsy; Follow-Up Studies; Humans; Phenobarbital; Phenytoin | 1967 |
Pseudolymphoma syndrome. A sensitivity to anticonvulsant drugs.
Topics: Biopsy; Blood Cell Count; Blood Chemical Analysis; Chlordiazepoxide; Drug Hypersensitivity; Female; Humans; Hydantoins; Hydrochlorothiazide; Lymphoma; Middle Aged; Phenobarbital; Phenytoin; Primidone; Seizures | 1968 |
Serum folate deficiency in children receiving anticonvulsant therapy.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Epilepsy; Erythrocyte Count; Folic Acid; Folic Acid Deficiency; Hematocrit; Hemoglobinometry; Humans; Phenobarbital; Phenytoin | 1968 |
Low specific gravity syndrome.
Topics: Adult; Anticonvulsants; Calcium; Chlorides; Chronic Disease; Creatinine; Epilepsy; Female; Humans; Intellectual Disability; Male; Mass Screening; Metabolic Clearance Rate; Middle Aged; Osmolar Concentration; Phenobarbital; Phenytoin; Potassium; Sodium; Specific Gravity; Time Factors; Urea; Urine; Vasopressins; Water-Electrolyte Balance | 1968 |
Influence of several drugs on the in vivo and in vitro activity of mammalian hepatic azo-reductase.
Topics: Animals; Caffeine; Guanethidine; Guinea Pigs; In Vitro Techniques; Iproniazid; Isoniazid; Liver; Nitrofurantoin; Oxidoreductases; Pentylenetetrazole; Phenobarbital; Phenylbutazone; Phenytoin; Rabbits; Rats; Sulfinpyrazone; Sulfonic Acids; Trimethadione | 1968 |
Growth hormone secretion during sleep.
Topics: Adult; Blood Glucose; Chlordiazepoxide; Chlorpromazine; Electroencephalography; Eye Movements; Female; Growth Hormone; Humans; Hydrocortisone; Imipramine; Insulin; Isocarboxazid; Male; Phenobarbital; Phenytoin; Secretory Rate; Sleep | 1968 |
Folic acid deficiency from anticonvulsant therapy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant; Male; Mental Processes; Phenobarbital; Phenytoin; Primidone; Protein Biosynthesis | 1968 |
[Course of epilepsy and significance of determination of phenytoin in the serum].
Topics: Child; Epilepsy; Humans; Phenobarbital; Phenytoin; Prognosis | 1968 |
Paroxysmal dystonic choreoathetosis. A family study and review of the literature.
Topics: Adult; Aged; Amobarbital; Athetosis; Atropine; Benzoates; Caffeine; Child, Preschool; Chorea; Coffee; Consciousness; Electroencephalography; Fatigue; Female; Functional Laterality; Humans; Male; Middle Aged; Motion Pictures; Muscles; Muscular Diseases; Neostigmine; Pedigree; Phenobarbital; Phenytoin; Phytotherapy; Stress, Physiological; Suggestion | 1968 |
Management of prolonged motor seiqure activity in children.
Topics: Child; Child, Preschool; Diazepam; Humans; Infant; Infant, Newborn; Injections, Intravenous; Phenobarbital; Phenytoin; Seizures | 1968 |
Study on combined treatment with phenobarbital and diphenylhydantoin.
Topics: Animals; Dogs; Drug Antagonism; Female; Male; Phenobarbital; Phenytoin | 1968 |
Plasma hydroxyproline in epilepsy.
Topics: Adolescent; Adult; Collagen; Connective Tissue; Epilepsy; Female; Humans; Hydroxyproline; Male; Methods; Middle Aged; Phenobarbital; Phenytoin | 1968 |
[On the problem of the treatment of cerebral epilepsy during pregnancy, labor and puerperium].
Topics: Anticonvulsants; Delivery, Obstetric; Epilepsy; Female; Humans; Obstetric Labor Complications; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Puerperal Disorders | 1968 |
Encephalopathy complicating burn injuries in children. Two cases showing reversible EEG changes.
Topics: Brain Diseases; Burns; Child; Child, Preschool; Electroencephalography; Female; Humans; Male; Neurologic Manifestations; Phenobarbital; Phenytoin | 1968 |
Mental effects of anticonvulsants, and folic acid metabolism.
Topics: Age Factors; Anemia, Macrocytic; Anticonvulsants; Brain; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Intellectual Disability; Male; Mental Disorders; Peripheral Nerves; Phenobarbital; Phenytoin; Primidone; Psychotic Disorders; Sex Factors; Spinal Cord; Vitamin B 12 | 1968 |
Effects of phenobarbital, phenytoin, and anoxia on connective tissue of mice.
Topics: Animals; Collagen; Connective Tissue; Electrolytes; Fats; Hydroxyproline; Hypoxia; Liver; Mice; Phenobarbital; Phenytoin; Potassium; Skin; Sodium; Water | 1968 |
Temporal lobe "spike focus" associated with confusion, complete amnesia and fugues in a paranoid schizophrenic.
Topics: Adult; Amnesia; Chlorpromazine; Cognition Disorders; Dissociative Disorders; Electroencephalography; Epilepsy, Temporal Lobe; Humans; Male; Paranoid Disorders; Phenobarbital; Phenytoin; Schizophrenia; Time Factors; Trifluoperazine | 1968 |
The effect of diphenylhydantoin on post tetanic excitability in isolated rabbit vagus.
Topics: Animals; Electric Stimulation; In Vitro Techniques; Nerve Fibers, Myelinated; Phenobarbital; Phenytoin; Rabbits; Time Factors; Vagus Nerve | 1968 |
Hematologic complications from tranquilizers in children.
Topics: Adolescent; Age Factors; Agranulocytosis; Bone Marrow Examination; Brain Damage, Chronic; Brain Diseases; Child; Dextroamphetamine; Eosinophilia; Female; Fluphenazine; Humans; Imipramine; Leukocyte Count; Leukocytosis; Leukopenia; Male; Methylphenidate; Phenobarbital; Phenytoin; Sex Factors; Thioridazine; Tranquilizing Agents | 1968 |
[Changing of the photosensible threshold in the electroencephalogram by drugs acting in the central nervous system].
Topics: Adolescent; Adult; Aged; Barbiturates; Central Nervous System; Child; Diazepam; Electroencephalography; Epilepsy; Evoked Potentials; Female; Humans; Injections, Intravenous; Light; Male; Middle Aged; Phenobarbital; Phenytoin | 1968 |
The effect of phenobarbital on diphenylhydantoin metabolism in children.
Topics: Child; Child, Preschool; Drug Synergism; Humans; Intellectual Disability; Phenobarbital; Phenytoin | 1969 |
Effects of antiepileptic drugs on brain energy reserves during convulsions.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Brain Chemistry; Cerebral Cortex; Electroshock; Glucose; Lactates; Mice; Phenobarbital; Phenytoin; Phosphocreatine; Seizures; Trimethadione | 1969 |
Tablets versus suspensions of anticonvulsants.
Topics: Anticonvulsants; Child; Economics; Humans; Phenobarbital; Phenytoin; Suspensions; Tablets | 1969 |
Thin-layer chromatography of anticonvulsant drugs.
Topics: Anticonvulsants; Chromatography, Thin Layer; Epilepsy; Humans; Hydantoins; Methods; Phenobarbital; Phenytoin; Primidone; Solvents; Time Factors | 1969 |
Simultaneous spectrophotometric determination of diphenylhydantoin and phenobarbital in biologic specimens.
Topics: Hydrogen-Ion Concentration; Indicators and Reagents; Methods; Oxidation-Reduction; Phenobarbital; Phenytoin; Spectrophotometry; Ultraviolet Rays | 1969 |
Interactions between pharmaceutical compounds by thermal methods.
Topics: Acetaminophen; Aspirin; Atropine; Bile Acids and Salts; Caffeine; Drug Compounding; Drug Incompatibility; Drug Stability; Methods; Phenacetin; Phenobarbital; Phenytoin; Quinine; Temperature; Theophylline; Thermodynamics; Time Factors; Vitamin K | 1969 |
Hyperglycemia with relative hypoinsulinemia in diphenylhydantoin toxicity.
Topics: Adolescent; Arginine; Blood Glucose; Female; Glucose; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Phenobarbital; Phenytoin; Primidone | 1969 |
Differentiating spectrophotometric titration of phenobarbital-diphenylhydantoin combinations in nonaqueous medium.
Topics: Dosage Forms; Phenobarbital; Phenytoin; Spectrophotometry | 1969 |
Increased metabolism of metyrapone in rats pretreated with diphenylhydantoin or phenobarbital.
Topics: Adrenal Glands; Animals; Biotransformation; Chromatography, Thin Layer; Enzyme Induction; Epilepsy; Liver; Metyrapone; Microsomes; Phenobarbital; Phenytoin; Pituitary Function Tests; Rats; Stimulation, Chemical | 1969 |
Gas chromatographic analysis for anticonvulsant drugs in biologic fluids.
Topics: Anticonvulsants; Chromatography, Gas; Equipment and Supplies; Humans; Hydantoins; Methods; Phenobarbital; Phenytoin; Primidone; Time Factors | 1969 |
Factors affecting the rate of disappearance of amphetamine in rats.
Topics: Age Factors; Animals; Dextroamphetamine; Estradiol; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Rats; Sex Factors; Time Factors; Zoxazolamine | 1969 |
The influence of lynestrenol on the rate of metabolism of phenobarbital, phenytoin and hexobarbital in mice.
Topics: Animals; Bemegride; Electroshock; Enzyme Induction; Female; Hexobarbital; Lynestrenol; Male; Mice; Phenobarbital; Phenytoin; Seizures; Sleep; Time Factors | 1969 |
Folic acid and anticonvulsive drugs.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsy; Erythrocyte Count; Female; FIGLU Test; Folic Acid; Folic Acid Deficiency; Hematocrit; Humans; Male; Middle Aged; Neutrophils; Phenobarbital; Phenytoin; Primidone; Psychotic Disorders; Vitamin B 12 | 1969 |
[Electrophysiological studies on the mechanism of action of antiepileptics in animal experiments].
Topics: Animals; Anticonvulsants; Axons; Cats; Cerebral Cortex; Electric Stimulation; Hippocampus; Neural Conduction; Phenobarbital; Phenytoin; Rabbits; Spinal Cord; Synapses; Thalamus; Trimethadione | 1969 |
Effects of diphenylhydantoin and phenobarbital on the hydroxyproline contents of skin in pigs.
Topics: Animals; Collagen; Hydroxyproline; Liver; Phenobarbital; Phenytoin; Skin; Swine | 1969 |
[Comparative studies on the anticonvulsant activity of the pyrone compounds of Piper methysticum Forst].
Topics: Animals; Anticonvulsants; Injections, Intraperitoneal; Injections, Intravenous; Intestinal Absorption; Male; Mephenesin; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Plant Extracts; Plants; Procaine; Pyrans; Reserpine; Shock; Time Factors | 1969 |
The effect of phenobarbital on plasma diphenylhydantoin level and metabolism in man and in rat liver microsomes.
Topics: Animals; Carbon Isotopes; Drug Antagonism; Humans; Liver; Microsomes; Phenobarbital; Phenytoin; Rats | 1969 |
Methylphenidate interaction with both anticonvulsants and ethyl biscoumacetate.
Topics: Adult; Anticonvulsants; Ataxia; Brain Diseases; Child, Preschool; Depression, Chemical; Ethyl Biscoumacetate; Humans; In Vitro Techniques; Infant; Liver; Male; Methylphenidate; Phenobarbital; Phenytoin; Primidone | 1969 |
A sequential screning test based on the running component of audiogenic seizures in mice, including reference compound PD50 values.
Topics: Acetazolamide; Animals; Anticonvulsants; Atropine; Chloral Hydrate; Chlordiazepoxide; Ethosuximide; Haloperidol; Hydroxybutyrates; Hypnotics and Sedatives; Meprobamate; Methods; Mice; Motor Activity; Orphenadrine; Phenobarbital; Phenytoin; Primidone; Sound | 1969 |
Reversible absorptive defects in anticonvulsant megaloblastic anaemia.
Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Blood; Female; FIGLU Test; Folic Acid Deficiency; Humans; Malabsorption Syndromes; Male; Phenobarbital; Phenytoin; Urine; Vitamin B 12 Deficiency; Xylose | 1965 |
Induction of liver microsomal cortisol 6beta-hydroxylase by diphenylhydantoin or phenobarbital: an explanation for the increased excretion of 6-hydroxycortisol in humans treated with these drugs.
Topics: Animals; Chromatography, Paper; Guinea Pigs; Humans; Hydrocortisone; Liver; Microsomes; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Urine | 1965 |
The clinical use of serum determinations of phenytoin and phenobarbital in children.
Topics: Blood Chemical Analysis; Child; Humans; Phenobarbital; Phenytoin | 1965 |
The sedative and anticonvulsant activity of some substituted pyrrolidones and piperidones.
Topics: Animals; Behavior, Animal; Cats; Chlorpromazine; Dogs; Female; Glutethimide; Guinea Pigs; Male; Meprobamate; Mice; Phenobarbital; Phenytoin; Piperidines; Pyrrolidinones; Rabbits; Rats | 1965 |
Transplacental effects of drugs in mice.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Male; Maternal-Fetal Exchange; Methylcellulose; Mice; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Thalidomide; Thioridazine; Tranquilizing Agents; Urethane | 1965 |
[Services and perspectives of metabolic research on certain exogenous substances endowed with pharmacological activity].
Topics: Animals; Carbon Tetrachloride Poisoning; Humans; Microsomes; Pentobarbital; Pharmacology; Phenobarbital; Phenytoin; Proadifen; Rats; Substance-Related Disorders | 1965 |
[Contribution to the pharmacology of piperazine].
Topics: Animals; Citrates; Guinea Pigs; Heart; Intestines; Phenobarbital; Phenytoin; Piperazines; Rabbits; Tartrates | 1965 |
Effect of diphenylhydantoin and phenobarbital on overt and latent tetany.
Topics: Adolescent; Adult; Aged; Blood; Calcium; Child; Drug Synergism; Female; Humans; Hypocalcemia; Hypoparathyroidism; Magnesium; Middle Aged; Phenobarbital; Phenytoin; Phosphorus; Seizures; Sprue, Tropical; Tetany | 1966 |
The effects of anticonvulsant drugs on the permeability of brain cells to d-xylose.
Topics: Animals; Anticonvulsants; Biological Transport; Brain; Cell Membrane Permeability; Cerebral Cortex; Culture Techniques; Guinea Pigs; Phenobarbital; Phenytoin; Xylose | 1966 |
The estimation of some important anticonvulsant drugs in serum.
Topics: Anticonvulsants; Blood Chemical Analysis; Chemistry, Clinical; Chromatography, Thin Layer; Colorimetry; Humans; In Vitro Techniques; Phenobarbital; Phenytoin; Primidone | 1966 |
Diphenylhydantoin intoxication associated with hyperglycemia.
Topics: Humans; Hyperglycemia; Infant; Male; Phenobarbital; Phenytoin | 1966 |
Drug-induced systemic lupus erythematosus. Primidone as a possible cause.
Topics: Electroencephalography; Epilepsy; Female; Humans; Hydralazine; Hydroxychloroquine; Lupus Erythematosus, Systemic; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1966 |
Antagonism of urease toxicity by chemical agents and antisera.
Topics: Alloxan; Animals; Anticonvulsants; Arginine; Barbiturates; Glutamates; Immune Sera; Injections, Intraperitoneal; Male; Mice; Pentobarbital; Phenobarbital; Phenytoin; Rats; Trimethadione; Urease | 1966 |
Spectrophotometric determination of diphenylhydantoin.
Topics: Phenobarbital; Phenytoin; Spectrophotometry; Ultraviolet Rays | 1966 |
Interaction of amphetamine with anticonvulsant drugs. II. Effect of amphetamine on the absorption of anticonvulsant drugs.
Topics: Amphetamine; Animals; Anticonvulsants; Drug Antagonism; Drug Synergism; Electroconvulsive Therapy; Ethosuximide; Female; Male; Mice; Phenobarbital; Phenytoin | 1966 |
Disulfiramum (antabuse) as inhibitor of phenytoin metabolism.
Topics: Adult; Disulfiram; Drug Antagonism; Humans; Male; Phenobarbital; Phenytoin; Primidone; Spectrophotometry | 1966 |
[Combination effects. 2. Experimental conception and presentation of combination effects].
Topics: Drug Synergism; Models, Chemical; Morphine; Penicillins; Phenobarbital; Phenytoin; Streptomycin | 1966 |
The anticonvulsant action of inhibitors of carbonic anhydrase: relation to endogenous amines in brain.
Topics: Animals; Brain Chemistry; Carbonic Anhydrase Inhibitors; Dopamine; Iproniazid; Male; Methazolamide; Mice; Norepinephrine; Phenobarbital; Phenytoin; Reserpine; Serotonin | 1967 |
Post-hemiplegic epilepsy in the elderly.
Topics: Aged; Epilepsy; Female; Hemiplegia; Humans; Intracranial Embolism and Thrombosis; Male; Middle Aged; Phenobarbital; Phenytoin; Prognosis | 1967 |
Epilepsy--facts and fancy.
Topics: Electroencephalography; Epilepsy; Humans; Phenobarbital; Phenytoin | 1967 |
Drug effects on the spontaneous electrical activity of the squid giant axon.
Topics: Acetylcholine; Action Potentials; Animals; Anticonvulsants; Atropine; Axons; Barbiturates; Bromides; Chloroform; Chlorpheniramine; Chlorpromazine; Curare; Dopamine; Electrophysiology; Ethanol; Ethers; Evoked Potentials; Hydantoins; Mollusca; Muscles; Nortropanes; Parasympatholytics; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Procaine; Serotonin; Strychnine; Tetracaine; Tremorine; Trihexyphenidyl; Trimethadione | 1967 |
The influence of disulfiram and calcium carbimide on the serum diphenylhydantoin. Excretion of HPPH in the urine.
Topics: Acetazolamide; Adult; Aged; Alcoholism; Amitriptyline; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Cyanates; Disulfiram; Drug Synergism; Epilepsy; Humans; Hydroflumethiazide; Imipramine; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1967 |
An effect of diphenylhydantoin on posttetanic hyperpolarization of intramedullary nerve terminals.
Topics: Action Potentials; Anesthesia, Local; Animals; Cats; Electrophysiology; Injections, Intravenous; Laminectomy; Medulla Oblongata; Nerve Endings; Neural Conduction; Phenobarbital; Phenytoin; Succinylcholine; Tetany; Tracheotomy | 1967 |
Continuous muscle fibre activity in an Indian male with additional evidence of terminal motor fibre abnormality.
Topics: Adult; Electric Stimulation; Electromyography; Humans; Male; Motor Neurons; Muscular Diseases; Myofibrils; Nerve Endings; Neural Conduction; Phenobarbital; Phenytoin; Procaine; Succinylcholine; Thiopental | 1967 |
[Toxic epidermal necrolysis. Epidermolysis necroticans combustiforme].
Topics: Child, Preschool; Exanthema; Humans; Male; Phenobarbital; Phenytoin; Stevens-Johnson Syndrome | 1967 |
Phospholipids as ion exchangers: implications for a possible role in biological membrane excitability and anesthesia.
Topics: Anesthesia; Binding Sites; Calcium; Chloroform; Hydrogen-Ion Concentration; Ion Exchange; Membranes, Artificial; Metals; Methanol; Models, Biological; Pentobarbital; Phenobarbital; Phenytoin; Phosphatidylethanolamines; Phospholipids; Procaine; Sulfhydryl Compounds | 1967 |
Pharmacological properties of the isopropyl ester of o-sulfamoyl-benzoic acid.
Topics: Animals; Behavior, Animal; Benzoates; Carbamates; Carisoprodol; Chlordiazepoxide; Chlormezanone; Chlorzoxazone; Dogs; Drug Antagonism; Electroshock; Male; Mephenesin; Meprobamate; Methocarbamol; Mice; Muscles; Pentobarbital; Phenethylamines; Phenobarbital; Phenytoin; Rats; Reflex; Seizures; Sleep; Strychnine; Trimethadione; Zoxazolamine | 1967 |
Case of tuberous sclerosis and haemorrhagic retinopathy (with fundus photographs).
Topics: Adult; Amphetamine; Anemia, Macrocytic; Female; Folic Acid; Fundus Oculi; Humans; Phenobarbital; Phenytoin; Photography; Retinal Hemorrhage; Seizures; Tuberous Sclerosis | 1967 |
A comparison of the convulsant activity of procaine and pentylenetetrazol.
Topics: Animals; Anticonvulsants; Chlorpromazine; Dibenzylchlorethamine; Female; Hydroxybutyrates; Mice; Pentobarbital; Pentylenetetrazole; Phenobarbital; Phenytoin; Procaine; Reflex; Reserpine; Seizures | 1967 |
Effect of some anticonvulsant drugs on the spinal trigeminal nucleus.
Topics: Animals; Anticonvulsants; Blood Pressure; Body Temperature; Cats; Chloralose; Electric Stimulation; Electrophysiology; Imipramine; Maxillary Nerve; Neurons; Pentobarbital; Phenobarbital; Phenytoin; Spinal Cord; Trigeminal Nerve | 1967 |
Serum creatine phosphokinase activity in epilepsy. Clinical and experimental studies.
Topics: Animals; Child; Creatine Kinase; Electroshock; Epilepsy; Female; Gallamine Triethiodide; Humans; Male; Phenobarbital; Phenytoin; Rabbits; Seizures | 1967 |
Epilepsy induced by cardiac pacemaker.
Topics: Aged; Amobarbital; Digoxin; Epilepsy; Female; Humans; Nerve Crush; Pacemaker, Artificial; Phenobarbital; Phenytoin; Phonocardiography; Phrenic Nerve | 1967 |
Interaction of anticonvulsant drugs with adenosine receptors in the central nervous system.
Topics: Adenosine; Animals; Anticonvulsants; Brain; Caffeine; Carbamazepine; Cerebellum; Cerebral Cortex; Cyclic AMP; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1984 |
Anticonvulsant therapy and its possible consequences on peripheral nervous system: a neurographic study.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Neural Conduction; Peripheral Nerves; Peripheral Nervous System Diseases; Phenobarbital; Phenytoin | 1984 |
Phenytoin interacts with calcium channels in brain membranes.
Topics: Animals; Brain; Calcium; Carbamazepine; Clonazepam; In Vitro Techniques; Ion Channels; Male; Nifedipine; Nitrendipine; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1984 |
Diphenylhydantoin substrate induced difference spectra: inhibition by other anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Ethosuximide; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Spectrophotometry; Thiazines; Valproic Acid | 1980 |
Stereochemical similarities in chemically different antiepileptic drugs.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzeneacetamides; Diazepam; Molecular Conformation; Phenobarbital; Phenylacetates; Phenylbutyrates; Phenytoin; Procyclidine; Stereoisomerism; Structure-Activity Relationship; Trihexyphenidyl; Urea | 1980 |
The effects of phenobarbital and diphenylhydantoin on liver function and morphology.
Topics: Adolescent; Adult; Alanine Transaminase; Aspartate Aminotransferases; Child; Child, Preschool; Enzyme Induction; Female; gamma-Glutamyltransferase; Humans; Infant; Liver; Male; Nucleotidases; Phenobarbital; Phenytoin; Seizures | 1980 |
Measurement of hepatic drug-metabolizing enxyme activity in man. Comparison of three different assays.
Topics: Adult; Aged; Antipyrine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Glucaric Acid; Hepatitis; Histamine H1 Antagonists; Humans; Liver; Liver Cirrhosis; Male; Medroxyprogesterone; Middle Aged; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Prednisolone; Rifampin | 1980 |
Psychiatric implications of anticonvulsant drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
[Effects of drug interaction in infancy (author's transl)].
Topics: Carbamazepine; Child; Chloramphenicol; Clonazepam; Dexamethasone; Drug Interactions; Humans; Isoniazid; Metronidazole; Phenobarbital; Phenytoin; Sulfonamides; Valproic Acid | 1980 |
[Effect of barbexaclone treatment on thyroid function in epileptic children and juveniles (author's transl)].
Topics: Adolescent; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Propylamines; Succinimides; Thyroid Hormones | 1980 |
Changes in regional brain levels of amino acid putative neurotransmitters after prolonged treatment with the anticonvulsant drugs diphenylhydantoin, phenobarbitone, sodium valproate, ethosuximide, and sulthiame in the rat.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Ethosuximide; gamma-Aminobutyric Acid; Glutamates; Male; Neurotransmitter Agents; Organ Specificity; Phenobarbital; Phenytoin; Rats; Taurine; Thiazines; Valproic Acid | 1981 |
[Anticonvulsant action of di-N-propylacetate combined with benzodiazepines, phenobarbital and phenytoin].
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Diazepam; Drug Therapy, Combination; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Semicarbazides; Valproic Acid | 1981 |
Calcium uptake mechanisms affected by some convulsant and anticonvulsant drugs.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Barbiturates; Calcium; Cell Membrane Permeability; Convulsants; Ion Channels; Phenobarbital; Phenytoin; Rats; Synaptosomes | 1981 |
Aminophylline seizures in the rat.
Topics: Aminophylline; Animals; Diazepam; Male; Phenobarbital; Phenytoin; Rats; Seizures | 1981 |
Choice of anticonvulsants in epilepsy.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Epilepsy; Ethosuximide; Follow-Up Studies; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
Prophylaxis of febrile convulsions.
Topics: Humans; Infant; Phenobarbital; Phenytoin; Random Allocation; Seizures, Febrile | 1981 |
Enhancement of drug withdrawal convulsion by combinations of phenobarbital and antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Drug Combinations; Drug Tolerance; Humans; Male; Phenobarbital; Phenytoin; Prohibitins; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome | 1981 |
Effect of antiepileptic drugs on the cerebral amino acid uptake in vitro.
Topics: Absorption; Amino Acids; Animals; Anticonvulsants; Brain; Clonazepam; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Neurotransmitter Agents; Phenobarbital; Phenytoin; Valproic Acid | 1981 |
Comparative assessment of the anticonvulsant activity of some benzodiazepines, phenobarbitone and diphenylhydantoin against maximal electroshock seizures in rats: a time-distribution study.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Electroshock; Female; Male; Phenobarbital; Phenytoin; Prohibitins; Rats; Rats, Inbred Strains; Seizures; Time Factors | 1981 |
The effects of convulsant and anticonvulsant drugs on the release of radiolabeled GABA, glutamate, noradrenaline, serotonin and acetylcholine from rat cortical slices.
Topics: Acetylcholine; Animals; Anticonvulsants; Cerebral Cortex; Culture Techniques; Diazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Norepinephrine; Phenobarbital; Phenytoin; Potassium; Prohibitins; Rats; Rats, Inbred Strains; Seizures; Serotonin | 1982 |
The influence of antiepileptic drugs on the electroencephalogram: a review of controlled clinical studies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
[Rise in gamma-GT during anticonvulsive therapy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
Effect of drugs on brain acetylcholine level in Gerbillus pyramidum.
Topics: Acetylcholine; Animals; Behavior, Animal; Brain; Female; Gerbillinae; Male; Meprobamate; Methamphetamine; Morphine; Pentobarbital; Phenobarbital; Phenytoin; Reserpine | 1983 |
The effect of five drugs in coma doses on neurotransmitter amino acids in the brains of guinea pigs.
Topics: Amino Acids; Animals; Brain; Brain Chemistry; Central Nervous System Agents; Central Nervous System Depressants; Diazepam; Flunitrazepam; Guinea Pigs; Neurotransmitter Agents; Phenobarbital; Phenytoin; Pregnanediones | 1983 |
Metabolic interactions of phenytoin in the rat: effect of coadministration with the anticonvulsant drugs sodium valproate, sulthiame, ethosuximide or phenobarbital.
Topics: Animals; Anticonvulsants; Brain; Drug Interactions; Ethosuximide; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Thiazines; Valproic Acid | 1984 |
Pharmacokinetics of antiepileptic drugs.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Ethosuximide; Female; Half-Life; Humans; Infant; Infant, Newborn; Intestinal Absorption; Kinetics; Male; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Valproic Acid | 1983 |
Pharmacodynamic factors in the occurrence of psychiatric symptoms among patients with epilepsy.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Epilepsy; Folic Acid; Humans; Kinetics; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid; Vitamin B 12 | 1983 |
Effects of excitatory amino-acid antagonists on the anticonvulsant action of phenobarbital or diphenylhydantoin in mice.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids; Animals; Anticonvulsants; Drug Interactions; Electroshock; Glutamates; Male; Mice; Phenobarbital; Phenytoin; Seizures; Valine | 1984 |
Inhibition of catecholamine transport into chromaffin granule ghosts isolated from bovine adrenal glands by phenytoin.
Topics: Adenosine Triphosphatases; Adrenal Glands; Animals; Biological Transport, Active; Ca(2+) Mg(2+)-ATPase; Catecholamines; Cattle; Chromaffin Granules; Chromaffin System; Dose-Response Relationship, Drug; Kinetics; Membrane Potentials; Norepinephrine; Phenobarbital; Phenytoin | 1984 |
A rapid gas liquid chromatography method for simultaneous determination of various anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Accelerated metabolism of probenecid during long-term treatment of rats with anticonvulsant drugs: effect on central serotonin turnover studies.
Topics: Animals; Anticonvulsants; Brain; Hydroxyindoleacetic Acid; Male; Phenobarbital; Phenytoin; Probenecid; Rats; Serotonin; Time Factors | 1981 |
Plasma concentrations of valproate during maintenance therapy in epileptic children.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Female; Half-Life; Humans; Male; Phenobarbital; Phenytoin; Valproic Acid | 1982 |
Fetal anticonvulsant syndrome in rats: dose- and period-response relationships of prenatal diphenylhydantoin, trimethadione and phenobarbital exposure on the structural and functional development of the offspring.
Topics: Abnormalities, Drug-Induced; Animals; Behavior, Animal; Developmental Disabilities; Dose-Response Relationship, Drug; Female; Fetus; Gestational Age; Humans; Locomotion; Oxazoles; Phenobarbital; Phenytoin; Pregnancy; Rats; Rats, Inbred Strains; Reflex, Startle; Swimming; Syndrome; Time Factors; Trimethadione | 1983 |
Antiepileptic agents affect hypothalamic beta-endorphin concentrations.
Topics: Animals; Anticonvulsants; beta-Endorphin; Endorphins; Ethosuximide; Hypothalamus; Kinetics; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Somatostatin; Substance P; Valproic Acid | 1984 |
Serum zinc and vitamin E concentrations in handicapped children treated with anticonvulsants.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Disabled Persons; Humans; Phenobarbital; Phenytoin; Vitamin E; Zinc | 1982 |
Hair copper and zinc concentrations in handicapped children treated with anticonvulsants.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Copper; Diazepam; Disabled Persons; Female; Hair; Hemoglobins; Humans; Male; Phenobarbital; Phenytoin; Zinc | 1983 |
[Enzyme induction by antiepilepsirine in mice and rats].
Topics: Animals; Anticonvulsants; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Humans; Male; Mice; Phenobarbital; Phenytoin; Piperidines; Rats | 1984 |
[Hypersensitivity syndrome caused by phenytoins and phenobarbital].
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Female; Humans; Leukocytosis; Male; Middle Aged; Phenobarbital; Phenytoin; Prednisone | 1984 |
The effects of pentobarbital and related compounds on frog motoneurons.
Topics: Amino Acids; Animals; Anura; Bicuculline; Chloralose; Chlordiazepoxide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Motor Neurons; Muscimol; Pentobarbital; Phenobarbital; Phenytoin; Picrotoxin; Spinal Cord; Strychnine; Synaptic Transmission | 1980 |
Effect of dopaminergic and GABA-ergic drugs given alone or in combination on the anticonvulsant action of phenobarbital and diphenylhydantoin in the electroshock test in mice.
Topics: Amantadine; Aminooxyacetic Acid; Amphetamine; Animals; Apomorphine; Baclofen; Dopamine; Electroshock; Female; Fluphenazine; gamma-Aminobutyric Acid; Haloperidol; Hydroxybutyrates; Levodopa; Male; Mice; Phenobarbital; Phenytoin; Receptors, Neurotransmitter; Seizures | 1980 |
Phenytoin inhibition of cyclic guanosine 3':5'-monophosphate (cGMP) accumulation in neuroblastoma cells by calcium channel blockade.
Topics: Acetylcholine; Anticonvulsants; Binding, Competitive; Calcium; Calcium Channel Blockers; Cells, Cultured; Cyclic GMP; Ion Channels; Neuroblastoma; Phenobarbital; Phenytoin; Receptors, Muscarinic | 1980 |
Vitamin D metabolism in patients treated with phenytoin and phenobarbitone.
Topics: Calcifediol; Cholecalciferol; Half-Life; Humans; Hydroxycholecalciferols; Kinetics; Phenobarbital; Phenytoin; Tritium | 1980 |
Role of inhibitory mechanisms in trigeminal neuralgia.
Topics: Animals; Baclofen; Carbamazepine; Cats; Electric Stimulation; Maxillary Nerve; Neural Inhibition; Phenobarbital; Phenytoin; Synaptic Transmission; Trigeminal Neuralgia; Trigeminal Nuclei | 1981 |
Peripheral neuropathy in epileptic patients.
Topics: Epilepsy; H-Reflex; Humans; Neural Conduction; Peripheral Nervous System Diseases; Peroneal Nerve; Phenobarbital; Phenytoin; Primidone; Sural Nerve | 1981 |
Migraine with interparoxysmal sharp complexes in the EEG: clinical features and response to anticonvulsant drugs.
Topics: Adolescent; Adult; Child; Electroencephalography; Female; Humans; Male; Middle Aged; Migraine Disorders; Phenobarbital; Phenytoin | 1981 |
Influence of vitamin D3 status, phenobarbital, and diphenylhydantoin treatment on the plasma 25-hydroxyvitamin D3 concentrations in the rat.
Topics: Alanine Transaminase; Aniline Hydroxylase; Animals; Body Weight; Calcifediol; Cholecalciferol; Cytochrome P-450 Enzyme System; Hydroxycholecalciferols; Liver; Male; Phenobarbital; Phenytoin; Rats; Time Factors | 1981 |
Anticonvulsant peripheral neuropathy: a clinical and electrophysiological study of patients on single drug treatment with phenytoin, carbamazepine or barbiturates.
Topics: Adolescent; Adult; Aged; Barbiturates; Carbamazepine; Evoked Potentials, Somatosensory; Humans; Median Nerve; Middle Aged; Neural Conduction; Peripheral Nervous System Diseases; Phenobarbital; Phenytoin; Primidone; Sural Nerve | 1982 |
Programming of rat hepatic arylhydrocarbon hydroxylase activity during late neonatal period.
Topics: Animals; Animals, Newborn; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Caffeine; DNA; Female; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1982 |
Cyclic GMP and cyclic AMP in the cerebral cortex of mice during seizures induced by 3-mercaptopropionic acid: effects of anticonvulsant agents.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Cerebral Cortex; Cyclic AMP; Cyclic GMP; gamma-Aminobutyric Acid; Hybridization, Genetic; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Phenobarbital; Phenytoin; Seizures | 1980 |
Simultaneous determination of phenytoin and phenobarbital in serum or plasma by substrate-labeled fluorescent immunoassay.
Topics: beta-Galactosidase; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Phosphoric Diester Hydrolases; Time Factors | 1983 |
Amino acid metabolism in the brain with convulsive disorders. Part 2: The effects of anticonvulsants on convulsions and free amino acid patterns in the brain of El mouse.
Topics: Adrenocorticotropic Hormone; Amino Acids; Animals; Anticonvulsants; Brain; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Pyridoxine; Seizures | 1984 |
In vivo effects of phenytoin and phenobarbital on GABA receptors in rat cerebral cortex and cerebellum.
Topics: Animals; Cerebellum; Cerebral Cortex; gamma-Aminobutyric Acid; Kinetics; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Immunologic aspects of phenobarbital hypersensitivity.
Topics: Adolescent; Child; Child, Preschool; Drug Hypersensitivity; Humans; Infant; Lymphocyte Activation; Phenobarbital; Phenytoin; T-Lymphocytes | 1984 |
Logit-log calibration curves for EMIT assays.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Glucose-6-Phosphate; Glucosephosphates; Humans; Immunoenzyme Techniques; Kinetics; Mathematics; NAD; Phenobarbital; Phenytoin; Primidone; Spectrophotometry | 1983 |
Automated fluorometer/photometer system for homogeneous immunoassays.
Topics: Autoanalysis; Chromatography, Gas; Chromatography, High Pressure Liquid; Fluorometry; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Photometry; Reagent Kits, Diagnostic; Statistics as Topic; Theophylline | 1983 |
Semi-automated continuous-flow enzyme immunoassay for antiepileptic drugs in serum.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Reagent Kits, Diagnostic | 1983 |
Adaptation of microvolume EMIT assays for theophylline, phenobarbital, phenytoin, carbamazepine, primidone, ethosuximide, and gentamicin to a CentrifiChem chemistry analyzer.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Centrifugation; Ethosuximide; Gentamicins; Humans; Immunoenzyme Techniques; Microchemistry; Phenobarbital; Phenytoin; Primidone; Theophylline | 1983 |
Usefulness of enzyme multiplied immunoassay technique (EMIT) in the study of intoxications caused by anticonvulsive drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1983 |
Disposition of total and unbound prednisolone in renal transplant patients receiving anticonvulsants.
Topics: Adolescent; Adult; Anticonvulsants; Blood Proteins; Child; Female; Half-Life; Humans; Kidney Transplantation; Kinetics; Male; Middle Aged; Phenobarbital; Phenytoin; Prednisolone; Prednisone; Protein Binding | 1984 |
Simultaneous measurement of ethosuximide, primidone, phenobarbital, phenytoin, carbamazepine, and their bioactive metabolites by liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1984 |
Performance of a new automated substrate-labeled fluorescence immunoassay system evaluated by comparative therapeutic monitoring of five drugs.
Topics: Autoanalysis; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Drug Stability; Fluorescent Antibody Technique; Humans; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Spectrometry, Fluorescence; Theophylline | 1984 |
Clinical evaluation of the Abbott TDx fluorescence polarization immunoassay analyzer.
Topics: Digoxin; Evaluation Studies as Topic; Fluorescence Polarization; Gentamicins; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Radioimmunoassay; Theophylline | 1984 |
Anticonvulsant sensitivity of absence seizures in the tottering mutant mouse.
Topics: Animals; Anticonvulsants; Diazepam; Electroencephalography; Epilepsy, Absence; Ethosuximide; Genes, Recessive; Mice; Mice, Neurologic Mutants; Mutation; Phenobarbital; Phenytoin | 1983 |
A monkey model for status epilepticus: carbamazepine and valproate compared to three standard anticonvulsants.
Topics: Aluminum Hydroxide; Animals; Anticonvulsants; Carbamazepine; Diazepam; Macaca mulatta; Male; Phenobarbital; Phenytoin; Pyridoxine; Status Epilepticus; Valproic Acid | 1983 |
Reduction of two-drug therapy in intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Clonazepam; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Prospective Studies; Valproic Acid | 1983 |
Febrile seizures in epileptic chicks: the effects of phenobarbital, phenytoin and valproate.
Topics: Animals; Chickens; Disease Models, Animal; Phenobarbital; Phenytoin; Reaction Time; Seizures, Febrile; Valproic Acid | 1983 |
Tonic status epilepticus presenting as confusional state.
Topics: Adolescent; Cognition Disorders; Confusion; Diazepam; Electroencephalography; Humans; Male; Methylphenidate; Phenobarbital; Phenytoin; Sleep; Status Epilepticus; Valproic Acid | 1983 |
Therapeutic monitoring of serum antiepileptic drug levels.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Laboratories; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid | 1983 |
Delayed effects of drug exposure during pregnancy: reproductive function.
Topics: Animals; Anticonvulsants; Estrus; Female; Fertility; Luteinizing Hormone; Male; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Reproduction; Sexual Maturation; Testosterone; Valproic Acid | 1983 |
Serum folate concentrations during pregnancy in women with epilepsy: relation to antiepileptic drug concentrations, number of seizures, and fetal outcome.
Topics: Carbamazepine; Congenital Abnormalities; Epilepsy; Female; Fetal Death; Folic Acid; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1983 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Humans; Phenobarbital; Phenytoin; Status Epilepticus; Valproic Acid | 1983 |
Treatment of the nonconvulsive epilepsies.
Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1983 |
Antiepileptic drug therapy. Fine tuning the dosage regimen.
Topics: Anticonvulsants; Carbamazepine; Drug Administration Schedule; Drug Interactions; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Valproic Acid | 1983 |
[Pharmacotherapy of epilepsy--current problems and controversies].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Seizures, Febrile; Status Epilepticus; Valproic Acid | 1983 |
Effects of anticonvulsants on hyperthermia-induced seizures in the rat pup.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Temperature; Differential Threshold; Disease Models, Animal; Electroencephalography; Phenobarbital; Phenytoin; Rats; Seizures, Febrile; Valproic Acid | 1984 |
[Determination of plasma levels of anticonvulsant drugs. Preliminary report of our experiences].
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Clonazepam; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1983 |
Unnecessary polypharmacy in patients with frequent seizures.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Anticonvulsant potency of common antiepileptic drugs in the gerbil.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Ethosuximide; Female; Gerbillinae; Male; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1983 |
Side effects of phenobarbital and phenytoin during long-term treatment of epilepsy.
Topics: Abnormalities, Drug-Induced; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Endocrine System Diseases; Epilepsy; Female; Hematologic Diseases; Humans; Immunologic Deficiency Syndromes; Infant, Newborn; Long-Term Care; Neurons; Osteomalacia; Peripheral Nerves; Phenobarbital; Phenytoin; Pregnancy | 1983 |
Microscale ultrafiltration technique for determining free drug in 50-microL serum samples.
Topics: Animals; Chloramphenicol; Diazepam; Furosemide; Humans; Indomethacin; Infant; Infant, Newborn; Microchemistry; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Ultrafiltration; Valproic Acid | 1984 |
Antiepileptic drugs and psychiatric disorders: mechanism involved in manifestation of psychic symptoms of high blood level of antiepileptics.
Topics: Adult; Anticonvulsants; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Male; Mental Disorders; Phenobarbital; Phenytoin; Syndrome | 1983 |
Effects of some anticonvulsant drugs on brain GABA level and GAD and GABA-T activities.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Oxidoreductases; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
Enzyme induction in neonates after fetal exposure to antiepileptic drugs.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Anticonvulsants; Breath Tests; Carbamazepine; Carbon Radioisotopes; Enzyme Induction; Female; Humans; Infant, Newborn; Liver; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1983 |
The effects of various antiepileptic drugs on E-shock-induced amnesia in mice: dissociability of effects on convulsions and effects on memory.
Topics: Amnesia; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Electroshock; Ethosuximide; Humans; Male; Mice; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
Summing up of the success so far gained through choice of drugs or combinations of drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Cognition Disorders; Drug Therapy, Combination; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Psychotropic Drugs; Valproic Acid | 1984 |
Effects of anticonvulsants on learning: performance of pigeons under a repeated acquisition procedure when exposed to phenobarbital, clonazepam, valproic acid, ethosuximide and phenytoin.
Topics: Animals; Anticonvulsants; Clonazepam; Columbidae; Dose-Response Relationship, Drug; Ethosuximide; Learning; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
[The incidence of postoperative epilepsy and prophylactic anticonvulsants in patients with intracranial aneurysm].
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Phenobarbital; Phenytoin; Postoperative Complications; Valproic Acid | 1984 |
Clinical value of determination of serum concentration of antiepileptics.
Topics: Adolescent; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Infant, Newborn; Male; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet | 1984 |
A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients.
Topics: Anticonvulsants; Antipyrine; Carbamazepine; Enzyme Induction; Epilepsy; Female; Glucaric Acid; Half-Life; Humans; Immunoenzyme Techniques; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Pharmacologic therapy of seizures in the elderly.
Topics: Aged; Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Status Epilepticus; Valproic Acid | 1984 |
[Plasma levels of antiepileptic agents in the treatment of epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Anticonvulsant drugs alter plasma tryptophan concentrations in epileptic patients: implications for antiepileptic action and mental function.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; Epilepsies, Partial; Female; Humans; Kinetics; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Tryptophan | 1984 |
One drug for childhood grand mal: medical audit for three-year remissions.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Epilepsy in children.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; Epilepsies, Partial; Epilepsy; Ethosuximide; Humans; Infant; Medical History Taking; Narcolepsy; Phenobarbital; Phenytoin; Physical Examination; Sleep Wake Disorders | 1984 |
Glycine potentiates the action of some anticonvulsant drugs in some seizure models.
Topics: 3-Mercaptopropionic Acid; Acoustic Stimulation; Animals; Anticonvulsants; Disease Models, Animal; Drug Synergism; Glycine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1984 |
Studies on the mechanism of drug sensitization: T-cell-dependent popliteal lymph node reaction to diphenylhydantoin.
Topics: Animals; Binding Sites; Dose-Response Relationship, Drug; Drug Hypersensitivity; Lymph Nodes; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Phenobarbital; Phenytoin; Spleen; T-Lymphocytes | 1981 |
[Central depressive action of propranolol (author's transl)].
Topics: Animals; Central Nervous System Depressants; Female; Male; Mice; Phenobarbital; Phenytoin; Propranolol; Rats; Seizures | 1981 |
Drug-induced liver injury. In vitro demonstration of hypersensitivity to both phenytoin and phenobarbital.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Cross Reactions; Drug Hypersensitivity; Female; Humans; Lymphocyte Activation; Lymphocytes; Phenobarbital; Phenytoin | 1984 |
Simultaneous determination of phenytoin and phenobarbital in serum by spin immunoassay.
Topics: Humans; Immunoassay; In Vitro Techniques; Phenobarbital; Phenytoin | 1984 |
Medically resistant epilepsy: low levels of drugs in the brain or pharmacological inefficacy?
Topics: Adolescent; Adult; Brain; Drug Resistance; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin | 1984 |
Phenytoin and phenobarbital concentrations in renal insufficiency.
Topics: Humans; Kidney Diseases; Phenobarbital; Phenytoin | 1984 |
The effect of computer generated comments on the distribution of anticonvulsant concentrations.
Topics: Anticonvulsants; Carbamazepine; Chemistry, Clinical; Computers; Humans; Phenobarbital; Phenytoin | 1984 |
Primidone therapy in refractory neonatal seizures.
Topics: Drug Therapy, Combination; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Primidone; Seizures | 1984 |
Carbamazepine decreases catecholamine turnover in the rat brain.
Topics: alpha-Methyltyrosine; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Carbamazepine; Catecholamines; Dopamine; Dopamine beta-Hydroxylase; Female; Methoxyhydroxyphenylglycol; Methyltyrosines; Myocardium; Norepinephrine; Phenobarbital; Phenytoin; Probenecid; Rats; Rats, Inbred Strains | 1984 |
Functional palatal incompetence in the fetal anticonvulsant syndrome.
Topics: Abnormalities, Drug-Induced; Child, Preschool; Epilepsy; Female; Humans; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Velopharyngeal Insufficiency | 1984 |
[Simultaneous determination of 4 anticonvulsant drugs by high pressure liquid chromatography (HPLC)].
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone | 1984 |
Kinetics of misonidazole enantiomers.
Topics: Administration, Oral; Adult; Cimetidine; Drug Interactions; Female; Half-Life; Humans; Kinetics; Male; Misonidazole; Nitroimidazoles; Phenobarbital; Phenytoin; Stereoisomerism | 1984 |
Excretion of organic acids associated with biotin deficiency in chronic anticonvulsant therapy.
Topics: Adult; Anticonvulsants; Biotin; Carbamazepine; Carboxy-Lyases; Carboxylic Acids; Epilepsy; Female; Humans; Male; Methylmalonyl-CoA Decarboxylase; Phenobarbital; Phenytoin; Primidone | 1984 |
Splenic hemorrhage in a neonate of a mother on anticonvulsant therapy.
Topics: Female; Hemorrhage; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Seizures; Splenic Rupture | 1984 |
Statistical analysis of performance of a liquid chromatographic assay of anticonvulsants involving solvent-demixing extraction and reciprocal internal standardization.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin | 1984 |
Changes induced in human liver by long-term anticonvulsant therapy. Functional and ultrastructural data.
Topics: Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Endoplasmic Reticulum; Epilepsy; Humans; Liver Function Tests; Middle Aged; Phenobarbital; Phenytoin | 1984 |
Slow saccades and hypometria in anticonvulsant toxicity.
Topics: Brain; Eye Diseases; Eye Movements; Humans; Male; Middle Aged; Muscular Diseases; Phenobarbital; Phenytoin | 1984 |
Interactions between folate metabolism, phenytoin metabolism, and liver microsomal cytochrome P450.
Topics: Animals; Diet; Folic Acid; Folic Acid Deficiency; In Vitro Techniques; Liver; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1984 |
Prognosis of chronic epilepsy with complex partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; Humans; Phenobarbital; Phenytoin; Primidone; Prognosis | 1984 |
Neonatal status epilepticus II: Electroencephalographic aspects.
Topics: Electroencephalography; Follow-Up Studies; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Status Epilepticus | 1984 |
The simultaneous determination of five anti-epileptic drugs in plasma by high performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1984 |
Therapeutic plasma levels of phenytoin, phenobarbital, and carbamazepine: individual variation in relation to seizure frequency and type.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1984 |
Mutagenicity of antiepileptic drugs. II. Phenytoin, primidone and phenobarbital.
Topics: Animals; Biotransformation; Cells, Cultured; Chromosome Aberrations; Cricetinae; Female; Mutation; Ovary; Phenobarbital; Phenytoin; Primidone; Sister Chromatid Exchange | 1984 |
Chromosomal studies of peripheral blood from epileptic patients treated with phenobarbital and/or diphenylhydantoin.
Topics: Adult; Animals; Chromosome Aberrations; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Metaphase; Phenobarbital; Phenytoin; Pregnancy; Rats; Sister Chromatid Exchange | 1984 |
Management of subarachnoid hemorrhage.
Topics: Adolescent; Adult; Aminocaproic Acid; Antihypertensive Agents; Child; Cimetidine; Dexamethasone; Humans; Intracranial Pressure; Ischemic Attack, Transient; Phenobarbital; Phenytoin; Subarachnoid Hemorrhage | 1984 |
Decrease in L-type pyruvate kinase activity in rat liver by some promoters of hepatocarcinogenesis.
Topics: Animals; Carbon Tetrachloride Poisoning; Carcinogens; Diethylnitrosamine; Isoenzymes; Isomerism; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Phenobarbital; Phenytoin; Pyruvate Kinase; Rats; Rats, Inbred Strains; Saccharin | 1984 |
Effects of phenobarbital, diphenylhydantoin and carbamazepine on thyroid function in epileptic children.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Epilepsy; Humans; Phenobarbital; Phenytoin; Thyroid Gland | 1984 |
External quality assessment of serum drug determinations in the Nordic countries.
Topics: Anticonvulsants; Carbamazepine; Data Collection; Humans; Phenobarbital; Phenytoin; Quality Control; Reference Standards | 1984 |
Vitamin K-dependent proteins and anticonvulsant medication.
Topics: Adolescent; Adult; Aging; Anticonvulsants; Calcium-Binding Proteins; Child; Child, Preschool; Drug Interactions; Female; Humans; Infant; Male; Middle Aged; Osteocalcin; Phenobarbital; Phenytoin; Seizures; Vitamin K | 1983 |
The binding of chemically different psychotropic drugs to alpha 1-acid glycoprotein.
Topics: Diazepam; Haloperidol; Humans; Imipramine; Kinetics; Orosomucoid; Perazine; Phenobarbital; Phenytoin; Protein Binding; Psychotropic Drugs; Structure-Activity Relationship | 1983 |
Status epilepticus.
Topics: Diazepam; Humans; Phenobarbital; Phenytoin; Status Epilepticus | 1983 |
Gynecomastia in epileptics treated with phenobarbital, phenytoin and fluoresone: two case reports.
Topics: Adult; Drug Therapy, Combination; Epilepsy; Gynecomastia; Humans; Male; Phenobarbital; Phenytoin; Prolactin; Sulfones | 1983 |
Oxazepam pharmacokinetics in patients with epilepsy treated long-term with phenytoin alone or in combination with phenobarbitone.
Topics: Adult; Bilirubin; Dialysis; Drug Interactions; Epilepsy; Female; Humans; Kinetics; Male; Middle Aged; Oxazepam; Phenobarbital; Phenytoin; Protein Binding | 1983 |
The role of dexamethasone in the modification of misonidazole pharmacokinetics.
Topics: Adult; Aged; Dexamethasone; Drug Interactions; Female; Humans; Kinetics; Lung Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Misonidazole; Nitroimidazoles; Phenobarbital; Phenytoin | 1983 |
The role of microsomal enzyme inducers in the reduction of misonidazole neurotoxicity.
Topics: Adult; Aged; Drug Administration Schedule; Drug Interactions; Enzyme Induction; Half-Life; Humans; Kinetics; Microsomes, Liver; Middle Aged; Misonidazole; Nervous System Diseases; Nitroimidazoles; Phenobarbital; Phenytoin | 1983 |
The in vivo cytotoxic activity of procarbazine and procarbazine metabolites against L1210 ascites leukemia cells in CDF1 mice and the effects of pretreatment with procarbazine, phenobarbital, diphenylhydantoin, and methylprednisolone upon in vivo procarba
Topics: Animals; Drug Interactions; Leukemia L1210; Male; Methylprednisolone; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Procarbazine | 1983 |
High-performance liquid chromatography of anticonvulsants--micro-assay for phenytoin and phenobarbital.
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Humans; Microchemistry; Phenobarbital; Phenytoin | 1983 |
Evaluation of the Abbott TDx for the stat measurement of phenobarbital, phenytoin, carbamazepine, and theophylline.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Evaluation Studies as Topic; Fluorescence Polarization; Humans; Immunoassay; Microcomputers; Phenobarbital; Phenytoin; Theophylline | 1983 |
Effects of certain antiepileptics on cephaloridine- and cefazolin-induced seizures in rats.
Topics: Animals; Anticonvulsants; Behavior, Animal; Cefazolin; Cephaloridine; Diazepam; Electroencephalography; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Time Factors | 1983 |
Effects of phenobarbitone and phenytoin on folate catabolism in the rat.
Topics: Animals; Chemical Phenomena; Chemistry; Feces; Folic Acid; Kidney; Liver; Male; Phenobarbital; Phenytoin; Rats | 1983 |
Quinidine interaction with anticonvulsants.
Topics: Anticonvulsants; Child, Preschool; Drug Interactions; Half-Life; Humans; Male; Phenobarbital; Phenytoin; Quinidine | 1983 |
A quantitative determination of anticonvulsant-induced bone demineralization by an improved X-ray densitometry technique.
Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Anticonvulsants; Bone and Bones; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Microcomputers; Middle Aged; Minerals; Osteomalacia; Phenobarbital; Phenytoin; Time Factors | 1983 |
Reduction of polypharmacy for epilepsy in an institution for the retarded.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Intellectual Disability; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1983 |
Presenile cataracts in hydantoin-treated epileptic patients.
Topics: Adult; Animals; Cataract; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Rats | 1983 |
A rate nephelometric phenobarbital and phenytoin assay: analytical and correlation studies of a new single-point calibration immunoprecipitation inhibition method.
Topics: Chemical Precipitation; Chromatography, Gas; Humans; Immunochemistry; Nephelometry and Turbidimetry; Phenobarbital; Phenytoin; Precipitin Tests; Reagent Kits, Diagnostic | 1983 |
[Direct and indirect parameters of free thyroxine. I. Method, quality control and in vitro experiments on storage of samples and effect of drugs].
Topics: Aspirin; Blood Preservation; Drug Interactions; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Radioimmunoassay; Thyroxine | 1983 |
Evaluation of an automated immunochemistry analyzer, the Auto ICS.
Topics: Autoanalysis; Evaluation Studies as Topic; Humans; Immunochemistry; Immunoglobulins; Phenobarbital; Phenytoin | 1983 |
A design for the prospective evaluation of the efficacy and toxicity of antiepileptic drugs in adults.
Topics: Adult; Aged; Anticonvulsants; Behavior; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Electroencephalography; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Random Allocation; Seizures | 1983 |
Interaction between phenobarbital and thioridazine.
Topics: Anticonvulsants; Drug Interactions; Humans; Phenobarbital; Phenytoin; Thioridazine | 1983 |
Antiepileptic agents--primidone, phenobarbital, phenytoin, and carbamazepine by reversed-phase liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone; Statistics as Topic | 1984 |
Pharmacokinetics of paraldehyde disposition in the neonate.
Topics: Female; Humans; Infant, Newborn; Infusions, Parenteral; Kinetics; Male; Metabolic Clearance Rate; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus | 1984 |
The effect of phenytoin, phenobarbitone, dexamethasone and flurbiprofen on misonidazole neurotoxicity in mice.
Topics: Animals; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Female; Flurbiprofen; Glucuronidase; Mice; Mice, Inbred C57BL; Misonidazole; Nitroimidazoles; Peripheral Nerves; Phenobarbital; Phenytoin; Propionates | 1984 |
Effect of use of gel-barrier sampling tubes on determination of some antiepileptic drugs in serum.
Topics: Anticonvulsants; Blood Specimen Collection; Carbamazepine; Centrifugation; Chromatography, Liquid; Humans; Phenobarbital; Phenytoin; Time Factors | 1984 |
Tissue assay of phenobarbital, phenytoin and p-hydroxyphenytoin by high-performance liquid chromatography.
Topics: Animals; Brain; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Female; Fetus; Hydrogen-Ion Concentration; Kinetics; Liver; Phenobarbital; Phenytoin; Pregnancy; Rats; Spectrophotometry, Ultraviolet | 1984 |
Differential effects of baclofen, gamma-hydroxybutyric acid and muscimol on the protective action of phenobarbital and diphenylhydantoin against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Baclofen; Drug Interactions; Electroshock; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections, Intraventricular; Male; Mice; Muscimol; Oxazoles; Phenobarbital; Phenytoin; Sodium Oxybate | 1984 |
Serum concentrations and efficacy of phenytoin, phenobarbital, and primidone in canine epilepsy.
Topics: Animals; Dog Diseases; Dogs; Drug Therapy, Combination; Epilepsy; Phenobarbital; Phenytoin; Primidone | 1984 |
Prevalence of hypocalcemia and elevated serum alkaline phosphatase in patients receiving chronic anticonvulsant therapy.
Topics: Adolescent; Adult; Alkaline Phosphatase; Calcium; Child; Female; Humans; Hypocalcemia; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Seizures; Vitamin D | 1984 |
[Studies on development of the ultrafine size reduction method of slightly soluble medicinal crystals. V. Size reduction of phenytoin and phenobarbital].
Topics: Crystallization; Particle Size; Phenobarbital; Phenytoin; Solubility | 1984 |
Antiepileptic drug utilization in pediatric patients.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Humans; Infant; Infant, Newborn; Kinetics; Pediatrics; Phenobarbital; Phenytoin | 1984 |
Fluorescence polarization immunoassay IV. Determination of phenytoin and phenobarbital in human serum and plasma.
Topics: Chromatography, High Pressure Liquid; Fluorescence Polarization; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Radioimmunoassay | 1982 |
Competitive rate nephelometric immunoassay for determination of theophylline, phenobarbital, and dilantin in serum.
Topics: Humans; Immunoenzyme Techniques; Nephelometry and Turbidimetry; Phenobarbital; Phenytoin; Theophylline | 1982 |
Automation of the homogeneous substrate-labeled fluorescent immunoassay for theophylline in serum: application to the determination of phenytoin and phenobarbital in serum.
Topics: Autoanalysis; Fluorescent Antibody Technique; Humans; Indicators and Reagents; Phenobarbital; Phenytoin; Theophylline | 1982 |
[Anticonvulsive combined therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
Organic convergence spasm.
Topics: Adolescent; Alpha Rhythm; Brain; Carbamazepine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Tonic-Clonic; Eye Movements; Female; Humans; Neurologic Examination; Phenobarbital; Phenytoin; Spasm; Theta Rhythm | 1980 |
Effect of anticonvulsants on plasma haloperidol and thioridazine levels.
Topics: Adult; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Female; Haloperidol; Humans; Intellectual Disability; Male; Mesoridazine; Phenobarbital; Phenytoin; Thioridazine | 1980 |
Prompt resolution of osteomalacia by switching from phenytoin to phenobarbital.
Topics: Calcium; Epilepsy, Tonic-Clonic; Female; Humans; Hydroxycholecalciferols; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin | 1980 |
Valproic acid.
Topics: Adult; Drug Therapy, Combination; Humans; Male; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1980 |
Phenobarbital vs. phenytoin for grand mal epilepsy.
Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Administration Schedule; Epilepsy, Tonic-Clonic; Female; Gingival Hyperplasia; Humans; Hyperkinesis; Hypertrichosis; Male; Methods; Orthodontics, Corrective; Phenobarbital; Phenytoin; Stevens-Johnson Syndrome | 1980 |
Status epilepticus.
Topics: Anesthesia, General; Child; Child, Preschool; Diazepam; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy, Absence; Female; Humans; Infant; Lidocaine; Male; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus; Time Factors | 1980 |
[Differential treatment of epilepsy patients].
Topics: Anticonvulsants; Carbamazepine; Diagnosis, Differential; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Nitrazepam; Phenobarbital; Phenytoin | 1980 |
Interactions of valproic acid with phenytoin.
Topics: Adult; Drug Interactions; Half-Life; Humans; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Valproic Acid | 1980 |
Hepatotoxicity of sodium valproate and other anticonvulsants in rat hepatocyte cultures.
Topics: Animals; Anticonvulsants; Clonazepam; Culture Techniques; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Liver; Phenobarbital; Phenytoin; Primidone; Rats; Valproic Acid | 1980 |
[Problems of therapeutic service in primidone therapy].
Topics: Adolescent; Drug Administration Schedule; Drug Interactions; Epilepsy, Tonic-Clonic; Female; Half-Life; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
Pharmacokinetics of anticonvulsant drugs.
Topics: Anticonvulsants; Binding, Competitive; Brain; Carbamazepine; Drug Interactions; Drug Tolerance; Epilepsy; Folic Acid; Humans; Kinetics; Phenobarbital; Phenytoin; Protein Binding; Tissue Distribution; Valproic Acid | 1980 |
Adult-onset stuttering treated with anticonvulsants.
Topics: Adult; Brain Injuries; Carbamazepine; Drug Therapy, Combination; Epilepsy, Post-Traumatic; Female; Humans; Phenobarbital; Phenytoin; Stuttering | 1981 |
Monotherapy or polytherapy for epilepsy?
Topics: Adolescent; Adult; Carbamazepine; Clonazepam; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1981 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1981 |
Reduction of steady-state valproate levels by other antiepileptic drugs.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Interactions; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1981 |
[Polytherapy and monotherapy in the treatment of patients with epilepsy].
Topics: Adult; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Male; Phenobarbital; Phenytoin | 1981 |
Recent advances in the treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Valproic Acid | 1980 |
Only certain anticonvulsants protect against kainate neurotoxicity.
Topics: Animals; Anticonvulsants; Diazepam; Kainic Acid; Male; Nervous System Diseases; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1981 |
[Spindles and spike waves in the sleep EEG of epileptic patients under administration of phenobarbital (PB) and phenytoin (DPH) (author's transl)].
Topics: Electroencephalography; Epilepsy; Evoked Potentials; Humans; Phenobarbital; Phenytoin; Sleep Stages | 1981 |
Some behavioral effects of antiepileptic drugs during acute and prolonged treatment in the rat.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Tolerance; Motor Skills; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1981 |
Stuporous episodes during treatment with sodium valproate: report of seven cases.
Topics: Anticonvulsants; Cognition Disorders; Consciousness Disorders; Electroencephalography; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Valproic Acid | 1982 |
Effect of anticonvulsant drugs on kainic acid-induced epileptiform activity.
Topics: Animals; Anticonvulsants; Diazepam; Electroencephalography; Ethosuximide; Guinea Pigs; Hippocampus; Kainic Acid; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1982 |
Therapy of status epilepticus.
Topics: Anticonvulsants; Diazepam; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; Lorazepam; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus | 1982 |
Placental transfer of anticonvulsants (phenobarbital, phenytoin, valproic acid) and the elimination from neonates.
Topics: Anticonvulsants; Bilirubin; Female; Fetal Blood; Half-Life; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Valproic Acid | 1981 |
Brain maturation following administration of phenobarbital, phenytoin, and sodium valproate to developing rats or to their dams: effects on synthesis of brain myelin and other subcellular membrane proteins.
Topics: Animals; Anticonvulsants; Brain; Female; Intracellular Membranes; Membrane Proteins; Myelin Proteins; Organ Size; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Valproic Acid | 1982 |
Antipyrine disposition in relation to lowered anticonvulsant plasma level during pregnancy.
Topics: Adult; Anticonvulsants; Antipyrine; Delivery, Obstetric; Dose-Response Relationship, Drug; Epilepsy; Female; Half-Life; Humans; Infant, Newborn; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Postpartum Period; Pregnancy; Pregnancy Complications; Time Factors; Valproic Acid | 1982 |
[The distribution of drugs between plasma, brain and cerebrospinal fluid in the human].
Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Carbamazepine; Diazepam; Humans; Lithium; Nordazepam; Phenobarbital; Phenytoin; Primidone; Protein Binding; Psychotropic Drugs; Serum Albumin; Sulfamerazine | 1982 |
EEG quantification of drug level effects in monkey model of partial epilepsy.
Topics: Animals; Anticonvulsants; Circadian Rhythm; Clonazepam; Disease Models, Animal; Electroencephalography; Kinetics; Macaca mulatta; Male; Phenobarbital; Phenytoin; Primidone; Seizures; Valproic Acid | 1982 |
Two antiepileptic drugs for intractable epilepsy with complex-partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
[A study on cerebrospinal fluid and saliva to serum concentration ratios of anticonvulsants--Phenytoin, Phenobarbital, Valproic Acid and Primidone in epileptic patients].
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Saliva; Valproic Acid | 1982 |
[Studies on the mechanism of metabolic acidosis observed in the children treated with anticonvulsants].
Topics: Acidosis; Adolescent; Binding Sites; Calcium; Carbonic Anhydrases; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Erythrocytes; Female; Humans; Male; Parathyroid Hormone; Phenobarbital; Phenytoin | 1982 |
Decreased phenytoin level during antineoplastic therapy: a case report.
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Drug Interactions; Drug Therapy, Combination; Humans; Male; Methotrexate; Middle Aged; Phenobarbital; Phenytoin; Seizures; Vinblastine | 1983 |
[Mono- or polytherapy in the treatment of epileptic patients].
Topics: Anticonvulsants; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Spain; United Kingdom; United States | 1983 |
Treatment of status epilepticus in adults.
Topics: Acid-Base Equilibrium; Adult; Bicarbonates; Critical Care; Diazepam; Electrocardiography; Electroencephalography; Female; Humans; Intubation, Intratracheal; Lidocaine; Male; Paraldehyde; Partial Pressure; Phenobarbital; Phenytoin; Respiration, Artificial; Sodium; Status Epilepticus | 1983 |
Simultaneous very fast liquid-chromatographic analysis of ethosuximide, primidone, phenobarbital, phenytoin, and carbamazepine in serum.
Topics: Carbamazepine; Chromatography, Liquid; Economics; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1983 |
Effects of phenytoin, phenobarbital, and ascorbic acid on misonidazole elimination.
Topics: Adult; Ascorbic Acid; Drug Interactions; Female; Humans; Kinetics; Male; Misonidazole; Nitroimidazoles; Phenobarbital; Phenytoin; Protein Binding | 1983 |
General principles of treatment: status epilepticus in neonates.
Topics: Diagnosis, Differential; Diazepam; Humans; Infant, Newborn; Infant, Newborn, Diseases; Phenobarbital; Phenytoin; Seizures; Status Epilepticus | 1983 |
Efficacy of phenytoin in treatment of status epilepticus.
Topics: Brain; Diazepam; Humans; Phenobarbital; Phenytoin; Status Epilepticus | 1983 |
Presenile cataracts in phenytoin-treated epileptic patients.
Topics: Adult; Aging; Animals; Cataract; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Rodentia | 1983 |
[Monitoring therapy by analysis of the drug concentration of saliva].
Topics: Anticonvulsants; Carbamazepine; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Saliva | 1983 |
A rapid procedure for the simultaneous estimation of the anticonvulsant drugs, ethosuximide, phenobarbitone, phenytoin, and carbamazepine in serum using high-pressure liquid chromatography.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin | 1983 |
Simultaneous liquid chromatographic determination of chloramphenicol and antiepileptic drugs (phenobarbital, phenytoin, carbamazepine, and primidone) in plasma.
Topics: Adult; Anticonvulsants; Carbamazepine; Chloramphenicol; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1983 |
Serum concentration of clonazepam and the therapeutic effect of the drug.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Clonazepam; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1983 |
[Blood levels of anticonvulsants during hemodialysis].
Topics: Anticonvulsants; Child; Child, Preschool; Female; Humans; Kidney Failure, Chronic; Male; Phenobarbital; Phenytoin; Renal Dialysis | 1983 |
The influence of bilirubin, alcohol and certain drugs on the kinetics of 99mTc-Diethyl IDA (EHIDA) in humans.
Topics: Alcoholism; Bilirubin; Epilepsy; Ethanol; Humans; Imino Acids; Jaundice; Kinetics; Phenobarbital; Phenytoin; Technetium; Technetium Tc 99m Diethyl-iminodiacetic Acid | 1983 |
Neurologic aspects and treatment of La Crosse encephalitis.
Topics: Brain Edema; Child; Encephalitis, Arbovirus; Encephalitis, California; Humans; Phenobarbital; Phenytoin; Pseudotumor Cerebri; Recurrence; Seizures | 1983 |
Anticonvulsants and neurogenic pulmonary edema.
Topics: Adult; Humans; Male; Patient Compliance; Phenobarbital; Phenytoin; Pulmonary Edema; Seizures | 1983 |
Simultaneous high performance liquid-chromatographic determination of carbamazepine, carbamazepine-10,11-epoxide, ethosuximide, phenobarbital, phenytoin, primidone and phenylethylmalonamide in plasma.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1983 |
Recurrent spontaneous myoclonus in alcohol withdrawal.
Topics: Adult; Aged; Diagnosis, Differential; Drug Therapy, Combination; Electrocardiography; Ethanol; Female; Humans; Male; Myoclonus; Phenobarbital; Phenytoin; Recurrence; Substance Withdrawal Syndrome | 1983 |
[Radioimmunologic study of the plasma concentrations of folic acid and various antiepileptic preparations during the treatment of epileptic patients].
Topics: Adolescent; Adult; Anticonvulsants; Benzamidines; Drug Therapy, Combination; Epilepsy; Female; Folic Acid; Humans; Male; Phenobarbital; Phenytoin; Radioimmunoassay | 1983 |
Reports of two cases of autoimmune thyroiditis while receiving anticonvulsant therapy.
Topics: Adolescent; Autoantibodies; Autoimmune Diseases; Child; Ethosuximide; Female; Goiter; Humans; Phenobarbital; Phenytoin; Thyroiditis | 1983 |
[Teratogenic effects of anticonvulsants with the development of multiple congenital anomalies - report on 3 patients].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anticonvulsants; Child, Preschool; Female; Humans; Male; Phenobarbital; Phenytoin | 1983 |
Effect of restraint stress on anticonvulsant actions of phenobarbitone & diphenylhydantoin in rats.
Topics: Animals; Anticonvulsants; Humans; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Restraint, Physical; Seizures; Stress, Psychological | 1982 |
Alcohol, other drugs and the fetus.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Dextropropoxyphene; Diazepam; Drug Synergism; Female; Fetal Alcohol Spectrum Disorders; Fetus; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy | 1982 |
Phenobarbital and phenytoin in neonatal seizures.
Topics: Humans; Infant, Newborn; Infant, Newborn, Diseases; Phenobarbital; Phenytoin; Seizures | 1982 |
Anticonvulsant-induced rickets associated with renal tubular acidosis and normal level of serum 1,25-dihydroxyvitamin D.
Topics: Acetazolamide; Acidosis, Renal Tubular; Anticonvulsants; Calcitriol; Child; Female; Humans; Phenobarbital; Phenytoin; Rickets; Vitamin D | 1981 |
Improved isocratic liquid-chromatographic simultaneous measurement of phenytoin, phenobarbital, primidone, carbamazepine, ethosuximide, and N-desmethylmethsuximide in serum.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Reference Values; Succinimides | 1982 |
Quantitative simultaneous determination of eight common antiepileptic drugs and metabolites by liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Succinimides | 1981 |
Identification and treatment of status epilepticus.
Topics: Diazepam; Humans; Phenobarbital; Phenytoin; Status Epilepticus | 1980 |
A study of the action of anticonvulsant drugs on an experimental model of epilepsy.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Electric Stimulation; Epilepsy; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1980 |
Dental root abnormalities and gingival overgrowth in epileptic patients receiving anticonvulsant therapy.
Topics: Adolescent; Adult; Child; Epilepsy; Female; Gingival Hyperplasia; Humans; Intellectual Disability; Male; Odontogenesis; Odontometry; Phenobarbital; Phenytoin; Tooth; Tooth Resorption; Tooth Root | 1980 |
A new modified method of measurement of diphenylhydantoin and phenobarbital in serum by high pressure liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin | 1980 |
Prescribing patterns for epilepsy.
Topics: Adult; Anticonvulsants; Child; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization; Epilepsy; Humans; Netherlands; New Zealand; Norway; Patient Compliance; Phenobarbital; Phenytoin; Physicians, Family | 1981 |
Some immunological reactions during chronic treatment with antiepileptic drugs.
Topics: Adult; Antibody Formation; B-Lymphocytes; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; HLA Antigens; Humans; Immunity, Cellular; Male; Phenobarbital; Phenytoin; T-Lymphocytes | 1981 |
A comparative study of the effects of phenytoin and phenobarbital on electrically induced maximal seizures in frogs and mice.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Female; Hindlimb; Humans; Male; Mice; Phenobarbital; Phenytoin; Rana pipiens; Seizures; Species Specificity; Stereotyped Behavior | 1982 |
Steroid-specific and anticonvulsant interaction aspects of troleandomycin-steroid therapy.
Topics: Asthma; Dose-Response Relationship, Drug; Drug Interactions; Humans; Methylprednisolone; Phenobarbital; Phenytoin; Prednisolone; Troleandomycin | 1982 |
Anticonvulsant therapy and vitamin D metabolism: evidence for different mechanisms for phenytoin and phenobarbital.
Topics: 25-Hydroxyvitamin D 2; Animals; Body Weight; Diet; Ergocalciferols; Male; Parathyroid Hormone; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Vitamin D | 1980 |
Decreased serum 24,25-dihydroxyvitamin D concentration during long-term anticonvulsant therapy in adult epileptics.
Topics: Adolescent; Adult; Anticonvulsants; Calcifediol; Calcitriol; Carbamazepine; Ergocalciferols; Humans; Middle Aged; Phenobarbital; Phenytoin | 1982 |
T cell-dependent B cell lymphoproliferation and activation induced by the drug diphenylhydantoin.
Topics: Animals; Antibody-Producing Cells; B-Lymphocytes; Humans; Lymph Nodes; Lymphocyte Activation; Lymphocyte Cooperation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Nude; Penicillamine; Phenobarbital; Phenytoin; T-Lymphocytes; Thymectomy | 1982 |
On-line liquid-chromatographic analysis for drugs in serum with the Technicon "FAST-LC" system: performance data for theophylline and for four commonly used anticonvulsants and their metabolites.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1980 |
[A gas-chromatographic method for the determination of carbamazepine, phenobarbital, phenytoin and primidone in the same extract of serum (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Temperature | 1980 |
[Methods for determination of anticonvulsants in serum. The comparison of enzyme-immunoassay with high-performance liquid chromatography (author's transl)].
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1980 |
Emit assays for five major anticonvulsant drugs. An evaluation of adaptations to two discrete kinetic analyzers.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Cross Reactions; Ethosuximide; Evaluation Studies as Topic; Humans; Immunoenzyme Techniques; Indicators and Reagents; Phenobarbital; Phenytoin; Primidone | 1980 |
Rapid centrifugal analyzer enzyme immunoassays for phenytoin, phenobarbital, and primidone.
Topics: Computers; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Reagent Kits, Diagnostic | 1980 |
Purification of hapten-enzyme conjugates for enzymoimmunoassay.
Topics: Antigen-Antibody Complex; Glucosephosphate Dehydrogenase; Haptens; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Progesterone | 1980 |
Monitoring pediatric serum theophylline, phenobarbital, and phenytoin with the IL Multistat III.
Topics: Blood Chemical Analysis; Child; Child, Preschool; Humans; Immunoenzyme Techniques; Infant; Infant, Newborn; Minicomputers; Phenobarbital; Phenytoin; Quality Control; Theophylline | 1980 |
Enzyme immunoassay of phenobarbital, phenytoin, primidone, carbamazepine and theophylline with the Abbott VP Bichromatic Analyzer.
Topics: Carbamazepine; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1981 |
[The determination of anticonvulsant drug levels in blood by enzyme immunoassay: method and clinical application (author's transl)].
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Immunoenzyme Techniques; Male; Phenobarbital; Phenytoin; Primidone | 1980 |
Monitoring of therapeutic serum concentrations of antiepileptic drugs by a newly developed gas chromatographic procedure and enzyme immunoassay (EMIT): a comparative study.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Quality Control | 1981 |
Stability of antiepileptic drug level in serum. Reliability of enzyme immunoassay method.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Time Factors | 1980 |
Anticonvulsant drugs determined by EMIT in spiked brain samples: a correlation with HPLC values.
Topics: Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Chromatography, High Pressure Liquid; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1982 |
[Nephelometric inhibition immunoassay (NIIA), a new methodology for the determination of phenobarbital and phenytoin concentration in serum (author's transl)].
Topics: Humans; Immunoassay; Immunoenzyme Techniques; Nephelometry and Turbidimetry; Phenobarbital; Phenytoin | 1982 |
Determination of phenobarbital and phenytoin by gas-liquid chromatography with on-column methylation.
Topics: Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Reference Values | 1982 |
Dilantin toxicity in a preterm infant: persistent bradycardia and lethargy.
Topics: Bradycardia; Dose-Response Relationship, Drug; Heart; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Phenobarbital; Phenytoin; Seizures; Sleep Stages | 1982 |
Les torsades des pointes.
Topics: Adolescent; Diagnosis, Differential; Electrocardiography; Female; Heart Ventricles; Humans; Pacemaker, Artificial; Phenobarbital; Phenytoin; Potassium; Propranolol; Seizures; Tachycardia, Paroxysmal; Ventricular Fibrillation | 1982 |
Serum protein binding and free concentration of phenytoin and phenobarbitone in pregnancy.
Topics: Adult; Blood Proteins; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Protein Binding | 1982 |
Current concepts in neurology: management of status epilepticus.
Topics: Anticonvulsants; Diazepam; Drug Administration Schedule; Humans; Lorazepam; Phenobarbital; Phenytoin; Status Epilepticus | 1982 |
Quality of care of epilepsy in Italy: multi-hospital survey of diagnosis and treatment of 1104 epileptic patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Health Surveys; Hospitals; Hospitals, University; Humans; Infant; Italy; Male; Middle Aged; Phenobarbital; Phenytoin; Quality of Health Care | 1982 |
Iatrogenic behavioral and psychiatric symptoms in children with partial complex seizures.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Temporal Lobe; Female; Humans; Iatrogenic Disease; Male; Mental Disorders; Phenobarbital; Phenytoin | 1982 |
Maternal anticonvulsant therapy and hemorrhagic disease of the newborn.
Topics: Adult; Female; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Seizures; Vitamin K Deficiency Bleeding | 1982 |
Neonatal seizures: a survey of current practice.
Topics: Blood Glucose; Calcium; Diagnosis, Differential; Dose-Response Relationship, Drug; Electrolytes; Evaluation Studies as Topic; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases; Neonatology; Neurology; Pediatrics; Phenobarbital; Phenytoin; Seizures; Surveys and Questionnaires | 1982 |
Combined phenytoin and phenobarbital overdose.
Topics: Adult; Diuresis; Female; Humans; Kinetics; Phenobarbital; Phenytoin; Suicide; Time Factors | 1982 |
Anticonvulsant action of phenobarbital, diazepam, carbamazepine, and diphenylhydantoin in the electroshock test in mice after lesion of hippocampal pyramidal cells with intracerebroventricular kainic acid.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Electroshock; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Seizures | 1982 |
Comparison of phenytoin and phenobarbital effects on far-field auditory and somatosensory evoked potential interpeak latencies.
Topics: Epilepsy; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Humans; Phenobarbital; Phenytoin | 1982 |
Phenytoin: an inhibitor and inducer of primidone metabolism in an epileptic patient.
Topics: Adult; Drug Interactions; Epilepsy; Female; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1982 |
Interactions of phenobarbital with propranolol in the dog. 1. Plasma protein binding.
Topics: Animals; Blood Proteins; Dogs; Drug Interactions; Kinetics; Male; Models, Chemical; Orosomucoid; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Stimulation, Chemical; Time Factors | 1982 |
Blood-brain barrier transfer and cerebral uptake of antiepileptic drugs.
Topics: Anticonvulsants; Blood-Brain Barrier; Brain; Clonazepam; Diazepam; Humans; Models, Biological; Phenobarbital; Phenytoin; Time Factors | 1982 |
Arterial and venous concentrations of phenobarbital, phenytoin, clonazepam, and diazepam after rapid intravenous injections.
Topics: Anticonvulsants; Arteries; Clonazepam; Diazepam; Humans; Injections, Intravenous; Phenobarbital; Phenytoin; Time Factors; Veins | 1982 |
Effects of chlorpromazine and other drugs acting on the central nervous system on human sperm motility.
Topics: Caffeine; Central Nervous System; Chlorpromazine; Diazepam; Humans; In Vitro Techniques; Male; Phenobarbital; Phenytoin; Sperm Motility | 1982 |
Differences between the concentrations of antiepileptic drugs in normal and pathological human brain.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Carbamazepine; Child; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1982 |
Hepatic cirrhosis associated with long-term anticonvulsant drug therapy in dogs.
Topics: Animals; Anticonvulsants; Dog Diseases; Dogs; Female; Liver; Liver Cirrhosis; Male; Microscopy, Electron; Phenobarbital; Phenytoin; Primidone | 1982 |
A comparison of diphenylhydantoin metabolism in different tissues using high performance liquid chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Enzyme Induction; Liver; Lymphocytes; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Species Specificity | 1982 |
[Serum beta-glucuronidase activity in patients treated with phenobarbital and diphenylhydantoin].
Topics: Adult; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Female; Glucuronidase; Humans; Liver; Male; Middle Aged; Phenobarbital; Phenytoin | 1982 |
Cellular bases of barbiturate and phenytoin anticonvulsant drug action.
Topics: Animals; Barbiturates; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Neurons; Pentobarbital; Phenobarbital; Phenytoin; Synapses | 1982 |
Treatment with anticonvulsant drugs retards the development of brain-stimulation reward in the prefrontal cortex.
Topics: Animals; Anticonvulsants; Diazepam; Electric Stimulation; Frontal Lobe; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Rats; Reward; Self Stimulation; Sensory Thresholds | 1982 |
Drug interactions during anticonvulsant medication.
Topics: Anticonvulsants; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin | 1982 |
Calcium metabolism and vitamin D metabolite levels in children receiving anticonvulsant drugs.
Topics: Adolescent; Alkaline Phosphatase; Calcium; Child; Child, Preschool; Dihydroxycholecalciferols; Female; Humans; Hydroxycholecalciferols; Male; Parathyroid Hormone; Phenobarbital; Phenytoin; Phosphorus | 1982 |
[Effect of antiepileptic treatment with phenobarbital and phenytoin on various parameters of immunity. Comparative study].
Topics: Adult; Female; Humans; Immunity; Immunoglobulins; Lymphocyte Activation; Male; Phenobarbital; Phenytoin; Rosette Formation | 1982 |
Plasma levels and clinical effects of antiepileptic drugs in pregnant epileptic patients and their newborns.
Topics: Adult; Anticonvulsants; Clonazepam; Epilepsy; Female; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone | 1980 |
[Application of change-over designs in human pharmacology demonstrated by reaction-time measurements (author's transl)].
Topics: Humans; Pharmacology; Phenobarbital; Phenytoin; Reaction Time; Research Design | 1981 |
Episodic complete airway obstruction in infants.
Topics: Airway Obstruction; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Phenobarbital; Phenytoin; Pregnancy; Respiratory Therapy; Sleep Apnea Syndromes; Sudden Infant Death; Theophylline | 1981 |
Phenobarbital and phenytoin in neonatal seizures: metabolism and tissue distribution.
Topics: Brain; Drug Therapy, Combination; Half-Life; Humans; Infant, Newborn; Infant, Newborn, Diseases; Phenobarbital; Phenytoin; Seizures; Tissue Distribution | 1981 |
Nonlinear kinetics of phenytoin in children.
Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Epidermolysis Bullosa; Epilepsy; Female; Half-Life; Humans; Infant; Kinetics; Male; Metabolic Clearance Rate; Migraine Disorders; Phenobarbital; Phenytoin | 1982 |
Saliva phenobarbital and phenytoin concentrations in epileptic adolescents.
Topics: Adolescent; Child; Epilepsy; Female; Humans; Male; Patient Compliance; Phenobarbital; Phenytoin; Saliva | 1981 |
[The determination of anticonvulsants within the framework of the therapy service].
Topics: Anticonvulsants; Chromatography, Gas; Chromatography, Thin Layer; Humans; Pharmacy Service, Hospital; Phenobarbital; Phenytoin | 1980 |
Anterior spinal artery syndrome during the postpartum period.
Topics: Adult; Cerebral Hemorrhage; Epilepsy; Female; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Radiography; Vitamin K Deficiency Bleeding | 1981 |
Quantitative assessment of smooth-pursuit eye movements in healthy and epileptic subjects.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electrooculography; Epilepsy; Eye Movements; Humans; Intelligence; Phenobarbital; Phenytoin; Reflex, Abnormal | 1980 |
The effects of phenytoin on phenobarbitone and primidone metabolism.
Topics: Adult; Aged; Anticonvulsants; Drug Therapy, Combination; Humans; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1981 |
Critical periods for diphenylhydantoin and phenobarbital administration during gestation.
Topics: Animals; Avoidance Learning; Critical Period, Psychological; Female; Gestational Age; Phenobarbital; Phenytoin; Pregnancy; Rats | 1980 |
[Phenobarbital intoxication in a patient with primidone and diphenylhydantoin (author's transl)].
Topics: Adult; Drug Interactions; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1980 |
In vivo and in vitro availability of commercial phenytoin formulations containing phenobarbitone.
Topics: Adult; Biological Availability; Drug Combinations; Humans; Male; Phenobarbital; Phenytoin; Solubility | 1980 |
Rapid determination of anticonvulsant drugs by isothermal gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1981 |
Prediction of phenytoin dosage requirements.
Topics: Adolescent; Child; Drug Therapy, Combination; Humans; Phenobarbital; Phenytoin | 1981 |
Interactions among chloramphenicol, phenytoin, and phenobarbital in a pediatric patient.
Topics: Child; Chloramphenicol; Drug Interactions; Humans; Male; Phenobarbital; Phenytoin; Postoperative Complications | 1981 |
Evidence for a synergistic interaction between phenytoin and phenobarbital in experimental animals.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Male; Mice; Phenobarbital; Phenytoin; Rabbits; Statistics as Topic | 1981 |
[Influence of anti-epileptic drugs on blood lipid parameters: preliminary data].
Topics: Anticonvulsants; Carbamazepine; Cholesterol; Epilepsy; Humans; Lipids; Phenobarbital; Phenytoin; Triglycerides | 1981 |
Ictal effects of anticonvulsant medication withdrawal in epileptic patients.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome | 1981 |
Effects of anticonvulsants and methotrexate on calcium disposition.
Topics: Animals; Anticonvulsants; Calcium; Calcium Radioisotopes; Folic Acid; Intestinal Absorption; Male; Methotrexate; Mice; Phenobarbital; Phenytoin | 1980 |
[Polytherapy and monotherapy in the treatment of epileptic patients].
Topics: Adult; Computers; Drug Combinations; Epilepsy; Female; Humans; Male; Monitoring, Physiologic; Phenobarbital; Phenytoin | 1981 |
Rapid microanalysis of anticonvulsants by high-performance thin-layer chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Thin Layer; Humans; Phenobarbital; Phenytoin; Primidone; Reference Values | 1981 |
Synthesis and anticonvulsant activity of N-(benzoylalkyl)imidazoles and N-(omega-phenyl-omega-hydroxyalkyl)imidazoles.
Topics: Animals; Anticonvulsants; Female; Imidazoles; Male; Mice; Phenobarbital; Phenytoin; Seizures; Structure-Activity Relationship | 1981 |
Fluorescence polarization immunoassay. iii. an automated system for therapeutic drug determination.
Topics: Autoanalysis; Fluorescence Polarization; Gentamicins; Humans; Immunoassay; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Theophylline | 1981 |
[Gas chromatographic determination of phenytoin, phenobarbital and primidone: flash-methylation after direct addition of trimethyl-phenyl-ammonium hydroxide to the ethyl acetate extract (author's transl)].
Topics: Aniline Compounds; Chromatography, Gas; Humans; Methylation; Phenobarbital; Phenytoin; Primidone; Quaternary Ammonium Compounds | 1981 |
[Effect of inducers of mixed-function microsomal oxidases on the immune response of mice induced by heterologous erythrocytes].
Topics: Animals; Anti-Anxiety Agents; Antibody Formation; Benzodiazepines; Benzodiazepinones; Cytochrome P-450 Enzyme System; DDT; Diazepam; Enzyme Induction; Erythrocytes; Male; Methylcholanthrene; Mice; Phenobarbital; Phenytoin; Rifampin; Sheep | 1981 |
[Epilepsy and hypocalcemia. Further considerations on a case].
Topics: Adult; Calcium; Epilepsy; Female; Goiter; Humans; Hypocalcemia; Hypoparathyroidism; Phenobarbital; Phenytoin; Postoperative Complications; Thyroidectomy; Vitamin D | 1981 |
[Pharmacological influences on the brain level and transport of GABA. I) Effect of various antipileptic drugs on brain levels of GABA].
Topics: Animals; Biological Transport; Brain; Carbamazepine; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Mice; Phenobarbital; Phenytoin | 1981 |
Effect of anticonvulsant and antidepressant drugs on iodothyronines in serum.
Topics: Adult; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Dose-Response Relationship, Drug; Female; Humans; Male; Mianserin; Phenobarbital; Phenytoin; Primidone; Thyroid Hormones | 1980 |
[Mechanism of action of antiepileptic drugs].
Topics: Animals; Anticonvulsants; Barbiturates; Benzamidines; Cerebral Cortex; Chlordiazepoxide; Diazepam; Ganglia; Lorazepam; Male; Mollusca; Phenobarbital; Phenytoin; Rats | 1981 |
Effects of phenobarbital on plasma concentration of phenytoin and mortality of mice treated with phenytoin after electroshock.
Topics: Animals; Electroshock; Male; Mice; Mortality; Phenobarbital; Phenytoin | 1981 |
[Plasma levels of anti-epileptic drugs. Evaluation of determinations carried out in the years 1978-1979].
Topics: Anticonvulsants; Drug Interactions; Humans; Phenobarbital; Phenytoin | 1981 |
Carbamazepine, phenytoin and phenobarbital do not influence brain catecholamine uptake, in vivo, in male rats.
Topics: Animals; Brain; Carbamazepine; Catecholamines; Hydroxydopamines; Male; Nomifensine; Norepinephrine; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1981 |
Effect of diphenylhydantoin and its main hydroxylated metabolite on the pharmacokinetics and the urinary and biliary excretion of phenobarbital and its p-hydroxy metabolite.
Topics: Animals; Bile; Half-Life; Kinetics; Male; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Tissue Distribution | 1981 |
The synthesis of some 11C-labelled antiepileptic drugs with potential utility as radiopharmaceuticals: hydantoins and barbiturates.
Topics: Anticonvulsants; Barbital; Barbiturates; Carbon Radioisotopes; Hydantoins; Isotope Labeling; Mephenytoin; Phenobarbital; Phenytoin | 1981 |
Current treatment of status epilepticus.
Topics: Adult; Anticonvulsants; Child; Diagnosis, Differential; Diazepam; Humans; Hysteria; Injections, Intravenous; Intubation, Intratracheal; Phenobarbital; Phenytoin; Pneumonia, Aspiration; Pulmonary Edema; Spasm; Status Epilepticus | 1981 |
Pituitary-adrenal responses to sub-chronic treatment with phenobarbital and/or phenytoin (diphenylhydantoin) in rats.
Topics: Animals; Corticosterone; Drug Interactions; Male; Phenobarbital; Phenytoin; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Stress, Physiological; Time Factors | 1981 |
The formation of carbamazepine epoxide by rat liver microsomes: an investigation of the biphasic kinetic profile.
Topics: Aging; Animals; Carbamazepine; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1981 |
Plasma level analysis of some antiepileptic drugs in 180 patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin | 1980 |
The relationship between the serum levels of phenobarbital and diphenylhydantoin and clinical data in patients with drug resistant epilepsy.
Topics: Adolescent; Adult; Child; Child, Preschool; Drug Resistance; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1980 |
Antiepileptic drug levels and side effects in man.
Topics: Anticonvulsants; Electroencephalography; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Phenytoin and phenobarbitone plasma level-dose relationships in Chinese epileptic children in Singapore.
Topics: Adolescent; Child; Child, Preschool; China; Epilepsy; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Singapore | 1981 |
Monitoring of phenobarbitone and phenytoin therapy in small children by salivary samples.
Topics: Dose-Response Relationship, Drug; Humans; Infant; Phenobarbital; Phenytoin; Saliva; Seizures, Febrile | 1981 |
Role of carbamazepine in reducing polypharmacy in epilepsy.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1981 |
Folic acid and vitamin D status of young children receiving minimal anticonvulsant drug therapy.
Topics: Alkaline Phosphatase; Calcium; Child, Preschool; Female; Folic Acid; Hematocrit; Humans; Male; Nutritional Physiological Phenomena; Nutritional Requirements; Phenobarbital; Phenytoin; Phosphorus; Seizures; Vitamin D | 1981 |
Effect of anticonvulsants on in vitro prothrombin synthesis in adult and fetal rat liver.
Topics: Aging; Animals; Anticonvulsants; Female; In Vitro Techniques; Liver; Male; Phenobarbital; Phenytoin; Pregnancy; Prothrombin; Rats; Rats, Inbred Strains; Vitamin K Deficiency | 1981 |
Systematic method of development in liquid chromatography applied to the determination of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Ethosuximide; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Solubility; Temperature | 1981 |
Spectrophotometric determination of phenytoin in the presence of other anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Diazepam; Humans; Phenobarbital; Phenytoin; Primidone; Spectrophotometry, Ultraviolet | 1981 |
A prolonged severe intoxication after ingestion of phenytoin and phenobarbital.
Topics: Adult; Coma; Confusion; Female; Gastric Lavage; Humans; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Time Factors | 1981 |
[Diagnosis of osteopathy caused by antiepileptic drugs].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Bone Diseases; Carbamazepine; Epilepsy; Female; Femur; Hand; Humans; Lumbar Vertebrae; Male; Middle Aged; Osteomalacia; Osteoporosis; Pelvis; Phenobarbital; Phenytoin; Radiography | 1981 |
Improvement in antiepileptic drug levels following reduction of intervals between clinic visits.
Topics: Adolescent; Adult; Anticonvulsants; Appointments and Schedules; Carbamazepine; Epilepsy; Ethosuximide; Female; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1980 |
Measurement of anticonvulsants in serum by reversed-phase ion-pair liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Urea | 1980 |
Disposition of hexobarbital in intra- and extrahepatic cholestasis in man and the influence of drug metabolism-inducing agents.
Topics: Adult; Aged; Cholestasis, Extrahepatic; Cholestasis, Intrahepatic; Enzyme Induction; Female; Hexobarbital; Humans; Inactivation, Metabolic; Kinetics; Liver; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Phenytoin; Rifampin | 1980 |
Plasma high-density lipoprotein cholesterol in epileptics treated with various anticonvulsants.
Topics: Adult; Anticonvulsants; Carbamazepine; Cholesterol; Epilepsy; Female; Humans; Lipoproteins, HDL; Male; Middle Aged; Phenobarbital; Phenytoin; Triglycerides | 1980 |
Clinical pharmacokinetics: the pharmacological monitoring of plasmatic levels in therapy.
Topics: Digoxin; Drug Administration Schedule; Gentamicins; Humans; Kinetics; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Salicylates; Theophylline | 1980 |
Antiepileptic drug distribution in cerebral cortex, ammon's horn, and amygdala in man.
Topics: Adolescent; Adult; Amygdala; Anticonvulsants; Carbamazepine; Cerebral Cortex; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1980 |
Carbamazepine-induced leukocytosis.
Topics: Adult; Carbamazepine; Female; Humans; Leukocytosis; Neutrophils; Phenobarbital; Phenytoin; Seizures | 1980 |
Liquid-chromatographic method for simultaneous determination of phenytoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin in plasma and urine.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Microchemistry; Phenobarbital; Phenytoin; Urine | 1980 |
Improved gas--liquid chromatographic method for the simultaneous determination of phenobarbital, phenytoin, carbamazepine and primidone in biological fluids.
Topics: Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Therapy for status epilepticus.
Topics: Diazepam; Drug Therapy, Combination; Humans; Phenobarbital; Phenytoin; Status Epilepticus | 1980 |
High performance liquid chromatographic analysis of anti-convulsant drugs using radial compression columns.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Effects of nafenopin, diphenylhydantoin, phenobarbitone and some acetylenes on body composition: is there a relationship between decreased carcass lipid and increased liver size and induction of drug metabolizing enzymes?
Topics: Acetylene; Alkynes; Animals; Body Composition; Chemical Phenomena; Chemistry; Eating; Lipid Metabolism; Liver; Mice; Mice, Obese; Nafenopin; Organ Size; Oxygen Consumption; Phenobarbital; Phenytoin; Propionates | 1980 |
[A study of effects on antiepileptic drugs upon the hippocampal afterdischarge (author's transl)].
Topics: Animals; Anticonvulsants; Carbamazepine; Cats; Electric Stimulation; Female; Hippocampus; Male; Phenobarbital; Phenytoin; Seizures; Trimethadione | 1980 |
Multivariate statistical methods in toxicology: application to the analysis of outpatient clinical data for diphenylhydantoin and phenobarbital in the treatment of epilepsy.
Topics: Adolescent; Adult; Aging; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Statistics as Topic; Toxicology | 1980 |
Reassessment of the anticonvulsant activity of alpha, alpha-diphenyl-succinimide.
Topics: Animals; Anticonvulsants; Brain Chemistry; Electroshock; Mice; Phenobarbital; Phenytoin; Succinimides | 1980 |
Influence of phenytoin and phenobarbital on the disposition of a single oral dose of clonazepam.
Topics: Adult; Benzodiazepinones; Clonazepam; Drug Interactions; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Models, Biological; Phenobarbital; Phenytoin | 1980 |
[Management of the status epilepticus].
Topics: Anticonvulsants; Humans; Injections, Intravenous; Lidocaine; Phenobarbital; Phenytoin; Status Epilepticus | 1980 |
The perturbation of lipid bilayers by general anesthetics: a quantitative test of the disordered lipid hypothesis.
Topics: Anesthetics; Chemical Phenomena; Chemistry, Physical; Cholesterol; Lipid Bilayers; Liposomes; Phenobarbital; Phenytoin; Phosphatidylcholines | 1980 |
Flash-evoked afterdischarge in rat as a model of the absence seizure: dose-response studies with therapeutic drugs.
Topics: Acetazolamide; Animals; Dose-Response Relationship, Drug; Ethosuximide; Evoked Potentials; Male; Mephenytoin; Phenobarbital; Phenytoin; Photic Stimulation; Rats; Seizures; Trimethadione | 1980 |
[Panmyelopathy in combined epilepsy therapy using ethosuccimide, diphenylhydantoin, and phenobarbital in childhood].
Topics: Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Pancytopenia; Phenobarbital; Phenytoin | 1980 |
[Rational control of calcium metabolism in children treated with anticonvulsants].
Topics: Adolescent; Anticonvulsants; Calcium; Child; Child, Preschool; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
[Intensive care of severe preeclampsia-eclampsia. A report on 22 cases (author's transl)].
Topics: Acute Kidney Injury; Adolescent; Adult; Brain Edema; Critical Care; Diazepam; Dihydralazine; Eclampsia; Female; Humans; Hypertension; Monitoring, Physiologic; Phenobarbital; Phenytoin; Pre-Eclampsia; Pregnancy; Respiratory Insufficiency; Seizures | 1980 |
Rapid method for simultaneous determination of phenobarbital, diphenylhydantoin and their main hydroxylated metabolites by nitrogen-selective gas chromatography.
Topics: Animals; Bile; Chromatography, Gas; Phenobarbital; Phenytoin; Rats; Reference Values | 1980 |
Preliminary observations on the Quality Assurance Service Therapeutic Drug Monitoring Program.
Topics: Chemistry, Clinical; Computers; Drug Therapy; Pathology, Clinical; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quality Control; Reference Standards; Theophylline; United States | 1980 |
Practical and theoretical aspects of phenytoin administration. I. Relationship between dose and plasma concentration.
Topics: Adult; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1980 |
Pharmacological modification of amygdaloid-kindled seizures.
Topics: Amygdala; Animals; Diazepam; Electric Stimulation; Electrodes, Implanted; Ketamine; Male; Phenobarbital; Phenytoin; Rats; Seizures; Trimethadione | 1980 |
Spectrophotometric determination of phenobarbitone, methylphenobarbitone and phenytoin in tablets.
Topics: Mephobarbital; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet; Tablets | 1980 |
Anticonvulsant-induced unclassified porphyria.
Topics: Adult; Aminolevulinic Acid; Anticonvulsants; Diagnosis, Differential; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Porphobilinogen; Porphyrias; Porphyrins | 1980 |
Rapid quantitative determination of underivatized carbamazepine, phenytoin, phenobarbital and p-hydroxyphenobarbital in biological fluids by packed column gas chromatography.
Topics: Adult; Carbamazepine; Chromatography, Gas; Epilepsy; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1980 |
[Biotransformation of some antiepileptic drugs (author's transl)].
Topics: Anticonvulsants; Biotransformation; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
6 beta-Hydroxycortisol: a noninvasive indicator of enzyme induction.
Topics: 17-Hydroxycorticosteroids; Child; Child, Preschool; Enzyme Induction; Female; Humans; Hydrocortisone; Male; Phenobarbital; Phenytoin; Radioimmunoassay | 1981 |
Rate-nephelometric inhibition immunoassay of phenytoin and phenobarbital.
Topics: Antibodies; Apoferritins; Binding, Competitive; Haptens; Humans; Nephelometry and Turbidimetry; Phenobarbital; Phenytoin; Precipitin Tests | 1981 |
Liquid chromatography of anticonvulsants in an inappropriately drawn (lipemic) serum sample.
Topics: Adult; Anticonvulsants; Bloodletting; Chromatography, High Pressure Liquid; Fat Emulsions, Intravenous; Female; Humans; Phenobarbital; Phenytoin | 1981 |
Power spectral analysis of EEG characteristics during sleep in epileptics.
Topics: Adolescent; Adult; Carbamazepine; Circadian Rhythm; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Sleep, REM | 1981 |
Practical considerations in anticonvulsant therapy--Part 2.
Topics: Anticonvulsants; Benzodiazepines; Cost Control; Epilepsy; Ethosuximide; Humans; Monitoring, Physiologic; Patient Compliance; Patient Education as Topic; Pharmacists; Phenobarbital; Phenytoin; Primidone; Role; Valproic Acid | 1995 |
Anticonvulsant hypersensitivity syndrome.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Female; Fever; Humans; Lymphatic Diseases; Male; Phenobarbital; Phenytoin; Prognosis; Syndrome | 1995 |
The use of felbamate in patients with periodic lateralized epileptiform discharges (PLEDs).
Topics: Anticonvulsants; Dominance, Cerebral; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Epilepsia Partialis Continua; Felbamate; Humans; Male; Middle Aged; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Status Epilepticus | 1995 |
Automated analysis of free and total concentrations of three antiepileptic drugs in plasma with on-line dialysis and high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dialysis; Epilepsy; Humans; Phenobarbital; Phenytoin; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet | 1995 |
Interactions of phenobarbital and phenytoin with carbamazepine and its metabolites' concentrations, concentration ratios, and level/dose ratios in epileptic children.
Topics: Biotransformation; Carbamazepine; Child; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Female; Humans; Male; Oxidoreductases; Phenobarbital; Phenytoin | 1995 |
The clinical pharmacology of antiepileptic drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Humans; Phenobarbital; Phenytoin; Reference Values; Valproic Acid | 1995 |
Anticonvulsant activity of Casimiroa edulis in comparison to phenytoin and phenobarbital.
Topics: Administration, Oral; Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Injections, Subcutaneous; Male; Mexico; Pentylenetetrazole; Phenobarbital; Phenytoin; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Seizures | 1995 |
Anticonvulsant effect of intraventricular antiepileptic drugs. Experimental study.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Epilepsy; Injections, Intraventricular; Male; Midazolam; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Valproic Acid | 1995 |
Effect of antiepileptic drugs on absence-like seizures in the tremor rat.
Topics: Animals; Anticonvulsants; Data Interpretation, Statistical; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Injections, Intraperitoneal; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred WKY; Rats, Mutant Strains; Seizures; Time Factors; Trimethadione; Valproic Acid | 1995 |
Is there a pathophysiological and therapeutic link between panic disorder and epilepsy?
Topics: Adult; Brain; Carbamazepine; Electroencephalography; Epilepsy; Female; Humans; Magnetic Resonance Imaging; Panic Disorder; Phenobarbital; Phenytoin | 1995 |
Aspirin and anticonvulsant interaction.
Topics: Animals; Aspirin; Carbamazepine; Disease Models, Animal; Drug Synergism; Electroshock; Female; Male; Phenobarbital; Phenytoin; Rats; Seizures | 1995 |
Effect of phenytoin on phenobarbital pharmacokinetics in a patient with epilepsy.
Topics: Adult; Drug Interactions; Drug Monitoring; Epilepsy; Female; Humans; Phenobarbital; Phenytoin | 1995 |
Bradycardia as a presenting feature of late postpartum eclampsia.
Topics: Adult; Bradycardia; Drug Therapy, Combination; Eclampsia; Female; Humans; Magnesium Sulfate; Nifedipine; Phenobarbital; Phenytoin; Pregnancy; Puerperal Disorders; Time Factors | 1994 |
Antiepileptic treatment and risk for hepatobiliary cancer and malignant lymphoma.
Topics: Aged; Aged, 80 and over; Biliary Tract Neoplasms; Case-Control Studies; Epilepsy; Female; Humans; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Phenobarbital; Phenytoin; Thorium Dioxide | 1995 |
A new, non-pharmacologic model of convulsive status epilepticus induced by electrical stimulation: behavioral/electroencephalographic observations and response to phenytoin and phenobarbital.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy, Tonic-Clonic; Infusions, Intravenous; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Status Epilepticus | 1994 |
The stability of anticonvulsant drugs in whole blood.
Topics: Anticonvulsants; Carbamazepine; Drug Stability; Drug Storage; Humans; Phenobarbital; Phenytoin; Temperature; Valproic Acid | 1994 |
Nonlinear pharmacokinetics of cyclophosphamide in patients with metastatic breast cancer receiving high-dose chemotherapy followed by autologous bone marrow transplantation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Middle Aged; Models, Biological; Phenobarbital; Phenytoin; Thiotepa | 1995 |
Effects of the peptide BCH-325 upon the efficacy of common antiepileptic drugs.
Topics: Amino Acid Sequence; Animals; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Peptide Fragments; Phenobarbital; Phenytoin; Seizures; Sodium Channels; Synaptic Transmission; Valproic Acid | 1994 |
Detection of propan-1,2-diol in neonatal brain by in vivo proton magnetic resonance spectroscopy.
Topics: Brain Chemistry; Humans; Infant, Newborn; Magnetic Resonance Spectroscopy; Pharmaceutical Vehicles; Phenobarbital; Phenytoin; Propylene Glycol; Propylene Glycols; Seizures | 1994 |
Comparison of community and institutional prescription of antiepileptic drugs for individuals with learning disabilities.
Topics: Adult; Ambulatory Care; Anticonvulsants; Cognition Disorders; Day Care, Medical; Drug Therapy, Combination; Drug Utilization; England; Epilepsy; Female; Humans; Institutionalization; Intellectual Disability; Intelligence; Male; Phenobarbital; Phenytoin; Primidone; Social Behavior; State Medicine | 1994 |
Competitive NMDA receptor antagonists enhance the antielectroshock activity of various antiepileptics.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Carbamazepine; Drug Synergism; Electroshock; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Enhanced differential diagnosis of anticonvulsant hypersensitivity reactions by an integrated Bayesian and biochemical approach.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Bayes Theorem; Carbamazepine; Cell Death; Child; Diagnosis, Differential; Drug Eruptions; Female; Humans; Lymphocytes; Male; Middle Aged; Phenobarbital; Phenytoin; Predictive Value of Tests; Sensitivity and Specificity | 1994 |
Sex hormones, gonadotropins and prolactin in male epileptic subjects in remission: role of the epileptic syndrome and of antiepileptic drugs.
Topics: Adult; Androstenedione; Anticonvulsants; Carbamazepine; Dihydrotestosterone; Epilepsies, Partial; Epilepsy, Generalized; Estradiol; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Male; Middle Aged; Phenobarbital; Phenytoin; Prolactin; Sex Hormone-Binding Globulin; Testosterone; Thyrotropin-Releasing Hormone | 1994 |
Epilepsy treatment in The Netherlands. Comparison of matched groups of two medical centres.
Topics: Adolescent; Adult; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Female; gamma-Aminobutyric Acid; Humans; Male; Netherlands; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Statistics, Nonparametric; Treatment Outcome; Valproic Acid; Vigabatrin | 1994 |
Antiepileptic drug induced osteomalacic myopathy with hyperparathyroidism and nephrolithiasis.
Topics: Drug Therapy, Combination; Electromyography; Epilepsy, Tonic-Clonic; Humans; Hyperparathyroidism, Secondary; Kidney Calculi; Male; Middle Aged; Muscular Atrophy; Osteomalacia; Phenobarbital; Phenytoin | 1993 |
Phenytoin and phenobarbital: a comparison of their state-dependent effects.
Topics: Animals; Appetitive Behavior; Avoidance Learning; Discrimination Learning; Male; Phenobarbital; Phenytoin; Rats; Rats, Wistar | 1994 |
Acute encephalopathy and status epilepticus associated with human herpes virus 6 infection.
Topics: Comorbidity; Electroencephalography; Encephalitis; Exanthema Subitum; Fever; Herpesviridae Infections; Herpesvirus 6, Human; Humans; Immunoenzyme Techniques; Infant; Male; Phenobarbital; Phenytoin; Polymerase Chain Reaction; Status Epilepticus; Treatment Outcome | 1994 |
Comparative pharmacodynamics of hepatic cytochrome P450 2B induction by 5,5-diphenyl- and 5,5-diethyl-substituted barbiturates and hydantoins in the male F344/NCr rat.
Topics: Alkylation; Animals; Barbital; Cytochrome P-450 Enzyme System; Enzyme Induction; Hydantoins; Liver; Male; Organ Size; Oxazines; Phenobarbital; Phenytoin; Rats; Rats, Inbred F344 | 1994 |
Nurses fail to keep physicians informed of multiple seizures. Case in point: Glassman v. St. Joseph Hospital 631 N.E. 2d 1186--IL (1994).
Topics: Brain Damage, Chronic; Coronary Artery Bypass; Humans; Illinois; Male; Malpractice; Nursing Staff, Hospital; Phenobarbital; Phenytoin; Postoperative Complications; Seizures | 1994 |
[Antioxidative activity of drugs used in anticonvulsive therapy].
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Antioxidants; Benzodiazepines; Benzodiazepinones; In Vitro Techniques; Lipid Peroxidation; Models, Biological; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1993 |
Synthesis of polymer-coated mixed-functional packing materials for direct analysis of drug-containing serum and plasma by high-performance liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Polymers; Silicon Dioxide | 1994 |
Simple and accurate high-performance liquid chromatographic method for the measurement of three antiepileptics in therapeutic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1993 |
Factors affecting the determination of drugs and endogenous low molecular mass compounds in human serum by micellar electrokinetic capillary chromatography with direct sample injection.
Topics: Anticonvulsants; Blood Chemical Analysis; Buffers; Capillary Action; Chromatography; Ethosuximide; Humans; Kinetics; Micelles; Molecular Weight; Naproxen; Osmolar Concentration; Phenobarbital; Phenytoin; Primidone | 1994 |
Measurement of lamotrigine under conditions measuring phenobarbitone, phenytoin, and carbamazepine using reversed-phase high-performance liquid chromatography at dual wavelengths.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Lamotrigine; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet; Triazines | 1994 |
Simultaneous determination of felbamate, primidone, phenobarbital, carbamazepine, two carbamazepine metabolites, phenytoin, and one phenytoin metabolite in human plasma by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Quality Control; Regression Analysis; Spectrophotometry, Ultraviolet | 1994 |
[Gelastic seizures, precocious puberty and hypothalamic hamartomas. A case report and the contributions of Single Photon Emission Computed Tomography (SPECT)].
Topics: Adolescent; Epilepsy; Female; Hamartoma; Humans; Hypothalamus; Laughter; Magnetic Resonance Imaging; Phenobarbital; Phenytoin; Puberty, Precocious; Temporal Lobe; Tomography, Emission-Computed, Single-Photon | 1994 |
[Repetitive serum determinations of anticonvulsants in epileptic patients].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Chronic Disease; Epilepsy; Female; Humans; Middle Aged; Phenobarbital; Phenytoin; Time Factors; Treatment Refusal | 1993 |
Influence of aminophylline and 8-(p-sulfophenyl)theophylline on the anticonvulsive action of diphenylhydantoin, phenobarbital, and valproate against maximal electroshock-induced convulsions in mice.
Topics: Aminophylline; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Phenobarbital; Phenytoin; Seizures; Theophylline; Valproic Acid | 1993 |
Chronological changes of MRI findings on striatal damage after acute cyanide intoxication: pathogenesis of the damage and its selectivity, and prevention for neurological sequelae: a case report.
Topics: Adult; Basal Ganglia; Brain Diseases; Carbamazepine; Corpus Striatum; Epilepsy, Temporal Lobe; Humans; Magnetic Resonance Imaging; Male; Nifedipine; Phenobarbital; Phenytoin; Potassium Cyanide; Suicide, Attempted | 1993 |
Pharmacological characterization of phenytoin-resistant amygdala-kindled rats, a new model of drug-resistant partial epilepsy.
Topics: Amino Acids; Aminocaproates; Amygdala; Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Resistance; Electric Stimulation; Electrodes, Implanted; Epilepsies, Partial; Female; Kindling, Neurologic; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Valproic Acid; Vigabatrin | 1993 |
Evaluation of the cloned enzyme donor immunoassay for measurement of phenytoin and phenobarbital in serum.
Topics: Chromatography, High Pressure Liquid; Cross Reactions; Evaluation Studies as Topic; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet | 1993 |
Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Cimetidine; Diazepam; Female; Mice; Muscimol; Phenobarbital; Phenytoin; Picrotoxin; Receptors, GABA; Seizures; Strychnine | 1993 |
Evaluation of evacuated blood-collection tubes: effects of three types of polymeric separators on therapeutic drug-monitoring specimens.
Topics: Acrylic Resins; Blood Specimen Collection; Cell Separation; Cyclosporine; Digoxin; Drug Monitoring; Ethanol; Gentamicins; Humans; Phenobarbital; Phenytoin; Polyesters; Polymers; Silicones; Theophylline | 1993 |
Simultaneous determination of carbamazepine, phenytoin, phenobarbital, primidone and their principal metabolites by high-performance liquid chromatography with photodiode-array detection.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Saliva; Spectrophotometry, Ultraviolet | 1993 |
[Lennox syndrome associated with severe cerebellar dysfunction and peripheral neuropathy].
Topics: Adult; Anticonvulsants; Brain; Cerebellar Ataxia; Drug Therapy, Combination; Epilepsy, Generalized; Humans; Magnetic Resonance Imaging; Male; Peripheral Nervous System Diseases; Phenobarbital; Phenytoin; Syndrome | 1993 |
Pharmacokinetic interaction of zonisamide in rats. Effect of zonisamide on other antiepileptics.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Drug Interactions; Erythrocytes; In Vitro Techniques; Isoxazoles; Male; Phenobarbital; Phenytoin; Protein Binding; Rats; Rats, Wistar; Valproic Acid; Zonisamide | 1993 |
The expression of UDP-glucuronosyltransferases of the UGT1 family in human liver and kidney and in response to drugs.
Topics: Aged; Bilirubin; Female; Gene Expression; Glucuronates; Glucuronosyltransferase; Humans; Isoenzymes; Kidney; Liver; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Phenytoin; RNA, Messenger; Substrate Specificity | 1993 |
Human anti-endoplasmic reticulum autoantibodies produced in aromatic anticonvulsant hypersensitivity reactions recognise rodent CYP3A proteins and a similarly regulated human P450 enzyme(s)
Topics: Adult; Animals; Anticonvulsants; Autoantibodies; Autoantigens; Carbamazepine; Cell Line; Cross Reactions; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Drug Hypersensitivity; Endoplasmic Reticulum; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; Inactivation, Metabolic; Isoenzymes; Male; Mice; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Rats | 1993 |
Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers.
Topics: Animals; Anti-Bacterial Agents; Cytochrome P-450 Enzyme System; Dexamethasone; Erythromycin; Humans; In Vitro Techniques; Macrolides; Male; Microsomes, Liver; NADP; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Troleandomycin | 1993 |
Diazepam by continuous intravenous infusion for status epilepticus in anticonvulsant hypersensitivity syndrome.
Topics: Anticonvulsants; Child, Preschool; Diazepam; Drug Hypersensitivity; Female; Hospitals, Pediatric; Hospitals, University; Humans; Infusions, Intravenous; Phenobarbital; Phenytoin; Status Epilepticus; Syndrome | 1993 |
Performance of human mass balance/metabolite identification studies using stable isotope (13C, 15N) labeling and continuous-flow isotope-ratio mass spectrometry as an alternative to radioactive labeling methods.
Topics: Carbon Isotopes; Chromatography, High Pressure Liquid; Humans; Isotope Labeling; Mass Spectrometry; Nitrogen Isotopes; Pharmaceutical Preparations; Phenobarbital; Phenytoin | 1993 |
Five years of anticonvulsant monitoring on site at the epilepsy clinic.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; Outpatient Clinics, Hospital; Phenobarbital; Phenytoin; Prospective Studies; Scotland; Time Factors; Valproic Acid | 1993 |
An audit of therapeutic drug monitoring of anticonvulsants.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Drug Monitoring; Epilepsy; Humans; Medical Audit; Northern Ireland; Phenobarbital; Phenytoin; Valproic Acid | 1995 |
Induction of cytochrome P450 3A (CYP 3A) by E 5110, a non-steroidal anti-inflammatory agent (NSAID), and typical CYP 3A inducers in primary cultures of dog hepatocytes.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Cells, Cultured; Clofibrate; Clotrimazole; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dogs; Drug Interactions; Enzyme Induction; Liver; Male; Mixed Function Oxygenases; Omeprazole; Phenobarbital; Phenytoin; Pyrrolidinones; Rifampin; Steroid Hydroxylases | 1995 |
Short-term perioperative anticonvulsant prophylaxis for the surgical treatment of low-risk patients with intracranial aneurysms.
Topics: Adult; Aneurysm, Ruptured; Anticonvulsants; Craniotomy; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Phenobarbital; Phenytoin; Postoperative Complications; Premedication; Risk Factors; Seizures; Subarachnoid Hemorrhage; Treatment Outcome | 1995 |
A model for estimating individualized valproate clearance values in children.
Topics: Administration, Oral; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Male; Metabolic Clearance Rate; Models, Theoretical; Pharmacokinetics; Phenobarbital; Phenytoin; Valproic Acid | 1995 |
Lack of effect of histological lesions on the phenytoin and phenobarbital concentrations in the brain cortex of epileptic patients.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Cerebellum; Cerebral Cortex; Child, Preschool; Epilepsy; Female; Humans; Infant; Linear Models; Male; Middle Aged; Phenobarbital; Phenytoin | 1995 |
Crystallization of intact monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Antibody Specificity; Crystallization; Crystallography, X-Ray; Dog Diseases; Dogs; Female; Gentamicins; Immunoglobulin G; Immunoglobulin kappa-Chains; Lymphoma; Mice; Mice, Inbred BALB C; Phenobarbital; Phenytoin; Protein Conformation; Theophylline | 1995 |
Chemical kindling: implications for antiepileptic drugs - sensitive and resistant epilepsy models.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Picrotoxin; Rats; Rats, Wistar; Seizures | 1996 |
Pharmacology of cortical epileptic afterdischarges in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsies, Myoclonic; Epilepsy; Male; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Severity of Illness Index; Valproic Acid | 1996 |
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.
Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Cell Line; Clotrimazole; Colonic Neoplasms; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dexamethasone; DNA Primers; Doxorubicin; Gene Expression Regulation, Neoplastic; Humans; Midazolam; Mixed Function Oxygenases; Molecular Sequence Data; Multigene Family; Phenobarbital; Phenytoin; Polymerase Chain Reaction; Rifampin; Tumor Cells, Cultured; Verapamil | 1996 |
Effect of valproate on cerebral metabolism and blood flow: an 18F-2-deoxyglucose and 15O water positron emission tomography study.
Topics: Adult; Brain; Carbamazepine; Cerebrovascular Circulation; Deoxyglucose; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Oxygen Radioisotopes; Phenobarbital; Phenytoin; Tomography, Emission-Computed; Valproic Acid; Water | 1996 |
Increasing-current electroshock seizure test: a new method for assessment of anti- and pro-convulsant activities of drugs in mice.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Carbamazepine; Convulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; Ear; Electrodes; Electroshock; Ethosuximide; Injections, Intravenous; Male; Mice; Morphine; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1996 |
[Study of the influence of anticonvulsant treatment on thyroid function].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Enzyme-Linked Immunosorbent Assay; Epilepsy; Female; Humans; Hypothyroidism; Male; Middle Aged; Phenobarbital; Phenytoin; Prospective Studies; Thyroid Gland; Thyroid Hormones; Thyrotropin; Valproic Acid | 1995 |
Generalized convulsive status epilepticus.
Topics: Adolescent; Adult; Aged; Anesthetics; Anticonvulsants; Benzodiazepines; Child; Epilepsy, Generalized; Humans; Isoflurane; Midazolam; Middle Aged; Phenobarbital; Phenytoin; Propofol; Status Epilepticus | 1996 |
[Treatment of convulsions in newborn infants].
Topics: Anticonvulsants; Clonazepam; Drug Administration Schedule; Drug Therapy, Combination; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Retrospective Studies; Seizures | 1996 |
Clearance of phenytoin and valproic acid is affected by a small body weight reduction in an epileptic obese patient: a case study.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Half-Life; Humans; Metabolic Clearance Rate; Obesity; Phenobarbital; Phenytoin; Valproic Acid; Weight Loss | 1996 |
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid | 1996 |
The necessity of adjusting the dosage of zonisamide when coadministered with other anti-epileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Valproic Acid; Zonisamide | 1996 |
Anticonvulsant drug effects on spontaneous thalamocortical rhythms in vitro: phenytoin, carbamazepine, and phenobarbital.
Topics: Animals; Carbamazepine; Cerebral Cortex; Dose-Response Relationship, Drug; In Vitro Techniques; Mice; Mice, Inbred ICR; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Thalamus | 1996 |
Quantitative analysis of mixtures of metal-carbonyl complexes by Fourier-transform infrared spectroscopy: application to the simultaneous double immunoassay of antiepileptic drugs by the nonisotopic carbonyl metalloimmunoassay method.
Topics: Animals; Anticonvulsants; Carbamazepine; Evaluation Studies as Topic; Haptens; Humans; Immunoassay; Molecular Structure; Organometallic Compounds; Phenobarbital; Phenytoin; Spectroscopy, Fourier Transform Infrared | 1996 |
Xylazine impairs the anticonvulsant activity of conventional antiepileptic drugs in mice.
Topics: Anesthetics; Animals; Anticonvulsants; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraperitoneal; Male; Mice; Phenobarbital; Phenytoin; Xylazine | 1996 |
Relationship between ischemic damage and concentrations of phenytoin and phenobarbital in the brain cortex of epileptic patients in vegetative state at death.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Autopsy; Brain Ischemia; Case-Control Studies; Cerebral Cortex; Chromatography, High Pressure Liquid; Epilepsy; Female; Humans; Immunohistochemistry; Male; Middle Aged; Persistent Vegetative State; Phenobarbital; Phenytoin; Regression Analysis | 1996 |
Elevated plasma alpha 1-acid glycoprotein levels: lack of connection to resistance to vecuronium blockade induced by anticonvulsant therapy.
Topics: Adult; Alprazolam; Anticonvulsants; Atropine; Biomarkers; Carbamazepine; Drug Interactions; Drug Resistance; Humans; Hydroxyzine; Hypnotics and Sedatives; Middle Aged; Neuromuscular Nondepolarizing Agents; Neurosurgery; Orosomucoid; Phenobarbital; Phenytoin; Vecuronium Bromide | 1997 |
Population pharmacokinetics of felbamate in children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Drug Monitoring; Felbamate; Humans; Infant; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Seizures; Valproic Acid | 1997 |
The effects of anticonvulsant drugs on NMDA-EPSP, AMPA-EPSP, and GABA-IPSP in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; Male; N-Methylaspartate; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Valproic Acid | 1997 |
Effect of antiepileptic drugs and calcium channel blocker on hyperthermic seizures in rats: animal model for hot water epilepsy.
Topics: Animals; Anticonvulsants; Body Temperature; Calcium Channel Blockers; Disease Models, Animal; Electroencephalography; Epilepsy; Hippocampus; Hyperthermia, Induced; Injections, Intraperitoneal; Male; Nifedipine; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Seizures | 1996 |
Influence of isradipine, niguldipine and dantrolene on the anticonvulsive action of conventional antiepileptics in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Carbamazepine; Dantrolene; Dihydropyridines; Disease Models, Animal; Drug Interactions; Electroshock; Epilepsy; Female; Isradipine; Lethal Dose 50; Mice; Motor Activity; Phenobarbital; Phenytoin; Random Allocation; Seizures; Valproic Acid | 1997 |
N6-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive activity of antiepileptic drugs.
Topics: Adenosine; Animals; Anticonvulsants; Body Temperature; Carbamazepine; Darkness; Drug Synergism; Electroshock; Female; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Purinergic P1 Receptor Agonists; Valproic Acid | 1997 |
[Serum digitoxin in concomitant use of antiepileptics in routine therapy].
Topics: Anticonvulsants; Antidepressive Agents; Carbamazepine; Digitoxin; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Lithium Compounds; Male; Phenobarbital; Phenytoin | 1997 |
A rapid in vitro assay for evaluation of metabolism-dependent cytotoxicity of antiepileptic drugs on isolated human lymphocytes.
Topics: Acetaminophen; Animals; Anticonvulsants; Biological Assay; Carbamazepine; Cell Count; Cell Survival; Female; Fluorescence; Humans; In Vitro Techniques; Lymphocytes; Microsomes, Liver; Phenobarbital; Phenytoin; Rabbits | 1997 |
Anticonvulsant usage is associated with an increased risk of procarbazine hypersensitivity reactions in patients with brain tumors.
Topics: Adult; Anticonvulsants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carbamazepine; Cohort Studies; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Procarbazine; Retrospective Studies; Valproic Acid | 1997 |
Extrashot-ODS, a syringe-type minicolumn sample injector for a reversed-phase high-performance liquid chromatographic column. Application to antiepileptics in human sera.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Epilepsy; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1997 |
Micellar electrokinetic capillary chromatography for therapeutic drug monitoring of zonisamide.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Electrophoresis, Capillary; Fluorescence Polarization Immunoassay; Humans; Isoxazoles; Phenobarbital; Phenytoin; Zonisamide | 1997 |
Biotin biotransformation to bisnorbiotin is accelerated by several peroxisome proliferators and steroid hormones in rats.
Topics: Analysis of Variance; Animals; Anticonvulsants; Biotin; Biotransformation; Carbamazepine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Clofibrate; Dehydroepiandrosterone; Dexamethasone; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Male; Microbodies; Phenobarbital; Phenytoin; Radiometry; Rats; Rats, Sprague-Dawley; Steroids | 1997 |
Anticonvulsant cross-sensitivity.
Topics: Anticonvulsants; Carbamazepine; Cross Reactions; Drug Hypersensitivity; Humans; Phenobarbital; Phenytoin | 1997 |
If a first antiepileptic drug fails to control a child's epilepsy, what are the chances of success with the next drug?
Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cohort Studies; Drug Administration Schedule; Epilepsy; Follow-Up Studies; Humans; Nova Scotia; Phenobarbital; Phenytoin; Prognosis; Remission Induction; Treatment Failure | 1997 |
[Optimisation of epilepsy monotherapy (clinico-pharmacological study)].
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, High Pressure Liquid; Electroencephalography; Epilepsy; Follow-Up Studies; Half-Life; Humans; Phenobarbital; Phenytoin; Treatment Outcome | 1997 |
Disturbances in biotin metabolism in children undergoing long-term anticonvulsant therapy.
Topics: Anticonvulsants; Biotin; Carbamazepine; Child; Female; Humans; Male; Phenobarbital; Phenytoin; Valerates | 1998 |
Treatment of the epileptic patient in the dental office.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dental Care for Chronically Ill; Emergencies; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Humans; Liability, Legal; Male; Medical History Taking; Middle Aged; Patient Care Planning; Phenobarbital; Phenytoin; Valproic Acid | 1998 |
Status epilepticus.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Humans; Infusions, Intravenous; Lorazepam; Phenobarbital; Phenytoin; Status Epilepticus; United States | 1998 |
Pharmacologically induced embryonic dysrhythmia and episodes of hypoxia followed by reoxygenation: a common teratogenic mechanism for antiepileptic drugs?
Topics: Abnormalities, Drug-Induced; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; Carbamazepine; Female; Fetus; Heart; Humans; Hypoxia; Mice; Mice, Inbred C57BL; Phenobarbital; Phenytoin; Pregnancy; Rats; Trimethadione | 1998 |
The influence of L-NG-nitroarginine methyl ester, an inhibitor of nitric oxide synthase, upon the anticonvulsive activity of conventional antiepileptic drugs against maximal electroshock in mice.
Topics: Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Drug Antagonism; Electroshock; Enzyme Inhibitors; Female; Memory; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1998 |
Does antiepileptic therapy affect immune response?
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cytokines; Drug Therapy, Combination; Epilepsy; Felbamate; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Receptors, Interleukin-2; Triazines; Valproic Acid | 1998 |
Comparison of anti-epileptic drug levels in different cases of sudden death.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Cause of Death; Child; Child, Preschool; Death, Sudden; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Retrospective Studies; Seizures | 1998 |
Antiepileptic drugs in developing countries.
Topics: Anticonvulsants; Child; Clinical Trials as Topic; Developing Countries; Epilepsy; Humans; India; Phenobarbital; Phenytoin; Treatment Outcome | 1998 |
Antiepileptic drugs in developing countries.
Topics: Anticonvulsants; Developing Countries; Drug Utilization; Epilepsy; Humans; Phenobarbital; Phenytoin | 1998 |
The incorporation of lamotrigine into the routine automated sequential trace enrichment of dialysates assay of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Triazines | 1998 |
Phenytoin, phenobarbital, and midazolam fail to stop status epilepticus-like activity induced by low magnesium in rat entorhinal slices, but can prevent its development.
Topics: Animals; Anticonvulsants; Carbamazepine; Culture Techniques; Dose-Response Relationship, Drug; Drug Resistance; Electroencephalography; Entorhinal Cortex; Magnesium; Midazolam; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Status Epilepticus | 1998 |
Fosphenytoin in infants.
Topics: Anticonvulsants; Drug Therapy, Combination; Female; Humans; Hydrogen-Ion Concentration; Infant; Infant, Newborn; Male; Phenobarbital; Phenytoin; Prodrugs; Seizures | 1998 |
Initial treatment of generalized convulsive status epilepticus.
Topics: Adolescent; Adult; Anticonvulsants; Diazepam; Double-Blind Method; Electroencephalography; Emergencies; Humans; Lorazepam; Multicenter Studies as Topic; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Recurrence; Reproducibility of Results; Status Epilepticus | 1999 |
Comparison between premortem and postmortem serum concentrations of phenobarbital, phenytoin, carbamazepine and its 10,11-epoxide metabolite in institutionalized patients with epilepsy.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Hospitalization; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Postmortem Changes; Time Factors | 1999 |
Elevated plasma concentrations of homocysteine in antiepileptic drug treatment.
Topics: Age Factors; Ambulatory Care; Anticonvulsants; Carbamazepine; Convulsants; Depression, Chemical; Epilepsy; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Pyridoxine; Risk Factors; Sex Factors; Valproic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 1999 |
Anticonvulsant and neurotoxic effects of intracerebroventricular injection of phenytoin, phenobarbital and carbamazepine in an amygdala-kindling model of epilepsy in the rat.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Injections, Intraventricular; Kindling, Neurologic; Male; Nervous System; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Time Factors | 1999 |
Prenatal exposure to anticonvulsants and psychosexual development.
Topics: Anticonvulsants; Cross-Sectional Studies; Female; Follow-Up Studies; Gender Identity; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Psychosexual Development; Retrospective Studies; Sex Differentiation; Surveys and Questionnaires; Transvestism | 1999 |
Lamotrigine drug interactions in a TDM material.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Triazines; Valproic Acid | 1999 |
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics | 1999 |
Similar name, different diagnosis. When two patients shouldn't be in the same room.
Topics: Anticonvulsants; Drug Interactions; Humans; Medication Errors; Nursing Records; Phenobarbital; Phenytoin; Seizures | 1999 |
Clinical experience with new antiepileptic drugs: antiepileptic drugs in Europe.
Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cross-Cultural Comparison; Drug Approval; Drug Monitoring; Drug Prescriptions; Epilepsy; Europe; History, 20th Century; Humans; Phenobarbital; Phenytoin; Polypharmacy; Valproic Acid | 1999 |
NMDA- but not kainate-mediated events reduce efficacy of some antiepileptic drugs against generalized tonic-clonic seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Epilepsy, Tonic-Clonic; Kainic Acid; Male; Mice; N-Methylaspartate; Phenobarbital; Phenytoin; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1999 |
Subtherapeutic levels of phenytoin with standard doses in infants: need to review dosage schedule.
Topics: Anticonvulsants; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin | 1999 |
Treatment of neonatal seizures.
Topics: Anticonvulsants; Humans; Infant, Newborn; Intensive Care Units; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Treatment Outcome | 1999 |
Casimiroa edulis seed extracts show anticonvulsive properties in rats.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Male; Mexico; Pentylenetetrazole; Phenobarbital; Phenytoin; Plant Extracts; Prohibitins; Propylene Glycol; Rats; Rats, Wistar; Solubility; Time Factors | 1999 |
Effects of standard anticonvulsant drugs on different patterns of epileptiform discharges induced by 4-aminopyridine in combined entorhinal cortex-hippocampal slices.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamazepine; Entorhinal Cortex; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Male; Pentobarbital; Phenobarbital; Phenytoin; Prohibitins; Rats; Rats, Wistar; Valproic Acid | 2000 |
Improved sexual function in three men taking lamotrigine for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Erectile Dysfunction; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sexual Dysfunctions, Psychological; Triazines; Valproic Acid | 2000 |
[Dupuytren's and Ledderhose's diseases associated with chronic use of anticonvulsants. Case report].
Topics: Adult; Anticonvulsants; Diazepam; Dupuytren Contracture; Epilepsy; Foot Diseases; Humans; Male; Phenobarbital; Phenytoin; Time Factors | 1999 |
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenobarbital; Phenytoin; Primidone; Treatment Outcome; Valproic Acid; Vitamin B 12 | 2000 |
Changes in bone turnover and deoxypyridinoline levels in epileptic patients.
Topics: Adult; Alkaline Phosphatase; Amino Acids; Anticonvulsants; Bone and Bones; Calcium; Carbamazepine; Case-Control Studies; Epilepsy; Female; Humans; Male; Osteocalcin; Phenobarbital; Phenytoin; Sex Factors; Vitamin D | 2000 |
[Drug resistant epilepsy in Senegal: therapeutic, clinical and socioeconomic factors].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Resistance; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Senegal; Socioeconomic Factors; Valproic Acid | 1999 |
Association of prenatal phenobarbital and phenytoin exposure with small head size at birth and with learning problems.
Topics: Adult; Anticonvulsants; Cephalometry; Cognition; Cross-Sectional Studies; Epilepsy; Female; Follow-Up Studies; Humans; Infant, Newborn; Intelligence; Learning Disabilities; Male; Memory; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Retrospective Studies | 2000 |
A story of "Ayurvedic" tablets and misled epileptic patients.
Topics: Adolescent; Adult; Anticonvulsants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Male; Medicine, Ayurvedic; Phenobarbital; Phenytoin; Quackery | 1999 |
[Progressive, small spotted, confluent erythema with bullae formation and general symptoms. Acute Lyell syndrome].
Topics: Adult; Anticonvulsants; Diagnosis, Differential; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Stevens-Johnson Syndrome | 2000 |
Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers.
Topics: Allyl Compounds; Amitriptyline; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Northern; Brain; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Epoxide Hydrolases; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroid Hydroxylases; Stilbenes; Sulfides | 2000 |
Bone mineral density, vitamin D and anticonvulsant therapy.
Topics: Adult; Anticonvulsants; Bone Density; Case-Control Studies; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Retrospective Studies; Statistics, Nonparametric; Vitamin D | 2000 |
Effects of anticonvulsants on acute cypermethrin poisoning in mice and rats.
Topics: Animals; Anticonvulsants; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Insecticides; Male; Mice; Phenobarbital; Phenytoin; Pyrethrins; Rats | 2000 |
A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes.
Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Case-Control Studies; Cell Survival; Chemistry, Clinical; Child; Cohort Studies; Coloring Agents; Drug Hypersensitivity; Family Health; Female; HIV Seropositivity; Humans; Lamotrigine; Lymphocytes; Male; Mice; Microsomes, Liver; Middle Aged; Mitochondria; Phenobarbital; Phenytoin; Sensitivity and Specificity; Succinate Dehydrogenase; Sulfadiazine; Sulfamethoxazole; Sulfonamides; Tetrazolium Salts; Thiazoles; Time Factors; Triazines; Trimethoprim; Trypan Blue | 2000 |
Simultaneous spectrophotometric determination of phenobarbital, phenytoin and methylphenobarbital in pharmaceutical preparations by using partial least-squares and principal component regression multivariate calibration.
Topics: Least-Squares Analysis; Mephobarbital; Multivariate Analysis; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet | 2000 |
Treatment of nonfebrile status epilepticus in Rochester, Minn, from 1965 through 1984.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Child; Child, Preschool; Diazepam; Female; Humans; Infant; Infusions, Intravenous; Male; Middle Aged; Phenobarbital; Phenytoin; Retrospective Studies; Status Epilepticus; Treatment Failure | 2001 |
Hair analysis for pharmaceutical drugs. I. Effective extraction and determination of phenobarbital, phenytoin and their major metabolites in rat and human hair.
Topics: Adult; Animals; Anticonvulsants; Gas Chromatography-Mass Spectrometry; Hair; Humans; Hydroxylation; Male; Middle Aged; Phenobarbital; Phenytoin; Rats; Reproducibility of Results | 2001 |
The teratogenicity of anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Case-Control Studies; Congenital Abnormalities; Epilepsy; Face; Female; Fetal Growth Retardation; Fingers; Humans; Infant, Newborn; Logistic Models; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2001 |
Antiepileptic hypersensitivity syndrome in children.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Anticonvulsants; Child; Diethylcarbamazine; Drug Hypersensitivity; Female; Histamine H1 Antagonists; Humans; Infant; Liver; Male; Medical Records Systems, Computerized; Phenobarbital; Phenytoin; Syndrome | 2001 |
Protease inhibitors and anticonvulsants.
Topics: Anti-HIV Agents; Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; HIV Infections; HIV Protease Inhibitors; Humans; Isoenzymes; Phenobarbital; Phenytoin | 1997 |
A novel microphysiometer based on MLAPS for drugs screening.
Topics: Anticonvulsants; Biosensing Techniques; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Penicillin V; Phenobarbital; Phenytoin | 2001 |
Course of chronic focal epilepsy resistant to anticonvulsant treatment.
Topics: Adult; Anticonvulsants; Carbamazepine; Cluster Analysis; Disease Progression; Documentation; Drug Administration Schedule; Drug Resistance; Epilepsies, Partial; Female; Follow-Up Studies; Humans; Male; Periodicity; Phenobarbital; Phenytoin | 2001 |
Antiepileptic drugs increase plasma levels of 4beta-hydroxycholesterol in humans: evidence for involvement of cytochrome p450 3A4.
Topics: Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Cell Line; Cholagogues and Choleretics; Cholesterol; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Humans; Hydroxycholesterols; Insecta; Kinetics; Male; Microsomes; Middle Aged; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Recombinant Proteins; Ursodeoxycholic Acid | 2001 |
Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase.
Topics: Aldehyde Oxidoreductases; Animals; Anticonvulsants; Base Sequence; Brain; DNA Primers; Genotype; Glial Fibrillary Acidic Protein; Hydroxybutyrates; Immunohistochemistry; Mice; Mice, Knockout; Phenobarbital; Phenytoin; Receptors, GABA-B; Seizures; Succinate-Semialdehyde Dehydrogenase | 2001 |
Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues.
Topics: Amino Acids; Animals; Anticonvulsants; Catalysis; Crystallography, X-Ray; Cyclization; Drug Design; Hydantoins; Lactams; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Molecular Structure; Neuroblastoma; Pentylenetetrazole; Phenobarbital; Phenytoin; Proline; Rats; Seizures; Sodium Channels; Stereoisomerism; Structure-Activity Relationship; Tetrazoles; Tumor Cells, Cultured | 2001 |
Association of prenatal phenobarbital and phenytoin exposure with genital anomalies and menstrual disorders.
Topics: Adult; Anticonvulsants; Case-Control Studies; Cryptorchidism; Female; Follow-Up Studies; Genitalia; Humans; Male; Maternal Age; Maternal Exposure; Menstruation Disturbances; Phenobarbital; Phenytoin; Pregnancy; Retrospective Studies | 2001 |
Pervasive seizures caused by hypoxic-ischemic encephalopathy: treatment with intravenous paraldehyde.
Topics: Anticonvulsants; Cohort Studies; Diazepam; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Infusions, Intravenous; Paraldehyde; Phenobarbital; Phenytoin; Seizures | 2001 |
Phenobarbital and MK-801, but not phenytoin, improve the long-term outcome of status epilepticus.
Topics: Animals; Anticonvulsants; Behavior, Animal; Chronic Disease; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2002 |
[Treatment of febrile convulsions].
Topics: Age Factors; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Child, Preschool; Diazepam; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Seizures, Febrile; Time Factors; Valproic Acid | 2002 |
Influence of phenytoin on the disposition of irinotecan: a case report.
Topics: Adolescent; Anticonvulsants; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Brain Neoplasms; Camptothecin; Carboplatin; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Disease Progression; Drug Interactions; Enzyme Induction; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Irinotecan; Male; Melphalan; Mixed Function Oxygenases; Neoplasm Recurrence, Local; Ondansetron; Phenobarbital; Phenytoin; Pineal Gland; Pinealoma; Prodrugs; Salvage Therapy; Seizures | 2002 |
Determination of lamotrigine simultaneously with carbamazepine, carbamazepine epoxide, phenytoin, phenobarbital, and primidone in human plasma by SPME-GC-TSD.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Lamotrigine; Phenobarbital; Phenytoin; Primidone; Triazines | 2002 |
Evaluation of fluorescence polarization assays for measuring valproic acid, phenytoin, carbamazepine and phenobarbital in serum.
Topics: Anticonvulsants; Automation; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Fluorescence Polarization; Humans; Phenobarbital; Phenytoin; Reproducibility of Results; Valproic Acid | 2002 |
Anticonvulsant hypersensitivity syndrome with marked eosinophilia in treatment of diabetic neuropathy.
Topics: Adult; Anticonvulsants; Carbamazepine; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Hypersensitivity; Eosinophilia; Humans; Male; Phenobarbital; Phenytoin | 2002 |
Paraquat detoxicative system in the mouse liver postmitochondrial fraction.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cobalt; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred ICR; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Paraquat; Phenobarbital; Phenytoin; Proadifen; Rabbits; Rifampin; Troleandomycin; Vitamin E | 2002 |
Performance characteristics of four immunoassays for antiepileptic drugs on the IMMULITE 2000 automated analyzer.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Cross Reactions; Drug Monitoring; Humans; Immunoassay; Phenobarbital; Phenytoin; Reproducibility of Results; Sensitivity and Specificity; Uremia; Valproic Acid | 2002 |
Human herpesvirus 6 encephalitis associated with hypersensitivity syndrome.
Topics: Anticonvulsants; Antiporters; DNA, Viral; Drug Hypersensitivity; Encephalitis, Viral; Exanthema Subitum; Herpesvirus 6, Human; Humans; Limbic System; Magnetic Resonance Imaging; Male; Middle Aged; Phenobarbital; Phenytoin; Roseolovirus Infections; Saccharomyces cerevisiae Proteins | 2002 |
Effect of prenatal exposure to anticonvulsant drugs on dermal ridge patterns of fingers.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Dermatoglyphics; Epilepsy; Female; Fingers; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects | 2002 |
Relationship between changes in drug score, D-glucaric acid excretion, and gamma-glutamyltransferase and beta-glucuronidase serum activities during anticonvulsant treatment.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Enzyme Induction; Epilepsy; Female; Follow-Up Studies; gamma-Glutamyltransferase; Glucaric Acid; Glucuronidase; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors | 2002 |
Neonatal mydriasis: intravenous lidocaine adverse reaction.
Topics: Anti-Arrhythmia Agents; Anticonvulsants; Diagnosis, Differential; Drug Overdose; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Humans; Infant, Newborn; Lidocaine; Male; Mydriasis; Phenobarbital; Phenytoin | 2002 |
Effects of classical antiepileptics on thresholds for phenomena induced by cortical stimulation in rats.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electric Stimulation; Electroencephalography; Electrophysiology; Epilepsies, Myoclonic; Ethosuximide; Humans; Male; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Seizures | 2002 |
In vitro removal of therapeutic drugs with a novel adsorbent system.
Topics: Adsorption; Anti-Bacterial Agents; Biocompatible Materials; Carbamazepine; Digoxin; Glycopeptides; Hemoperfusion; Humans; Models, Biological; Phenobarbital; Phenytoin; Sorption Detoxification; Theophylline; Uremia; Valproic Acid | 2002 |
Characterization of pharmacoresistance to benzodiazepines in the rat Li-pilocarpine model of status epilepticus.
Topics: Animals; Anticonvulsants; Benzodiazepines; Chi-Square Distribution; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; Electroencephalography; Lithium Chloride; Male; Muscarinic Agonists; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Time Factors | 2002 |
Effects on toes from prenatal exposure to anticonvulsants.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Child; Child, Preschool; Epiphyses; Female; Fingers; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Teratogens; Toes | 2002 |
Lack of effects of prolonged treatment with phenobarbital or phenytoin on the expression of P-glycoprotein in various rat brain regions.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Female; Gene Expression Regulation; Phenobarbital; Phenytoin; Rats; Rats, Wistar | 2002 |
Therapeutic drug monitoring of anticonvulsant drugs by micellar HPLC with direct injection of serum samples.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Micelles; Phenobarbital; Phenytoin | 2002 |
Intracerebroventricular injection of the antibiotic cefoselis produces convulsion in mice via inhibition of GABA receptors.
Topics: Animals; Anti-Bacterial Agents; Anticonvulsants; Bicuculline; Carbamazepine; Ceftizoxime; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Phenobarbital; Phenytoin; Receptors, GABA; Seizures; Sodium Channel Blockers | 2002 |
Low-affinity kainate receptor-mediated events reduce the protective activity of phenobarbital and diphenylhydantoin against maximal electroshock in mice.
Topics: Animals; Electroshock; Glutamates; Male; Mice; Neuroprotective Agents; Phenobarbital; Phenytoin; Receptors, Kainic Acid | 2002 |
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid | 2003 |
Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity.
Topics: Animals; Anticonvulsants; Biological Transport; Blood-Brain Barrier; Drug Resistance, Multiple; Humans; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Phenobarbital; Phenytoin; Rats; Rats, Wistar | 2003 |
Evaluation of therapeutic drug monitoring of antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Hospitals, Teaching; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Polypharmacy; Valproic Acid | 2003 |
Determination of two ternary mixtures containing phenobarbitone by second derivative of the ratio spectrum-zero-crossing and HPLC methods.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Mephobarbital; Papaverine; Phenobarbital; Phenytoin; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Technology, Pharmaceutical; Theophylline | 2003 |
Tritiated thymidine incorporation does not enhance sensitivity of the popliteal lymph node assay.
Topics: Animals; Drug Evaluation, Preclinical; Female; Local Lymph Node Assay; Lymph Nodes; Male; Metformin; Mice; Mice, Inbred BALB C; Ofloxacin; Phenobarbital; Phenytoin; Random Allocation; Streptozocin; Sulfamethoxazole; Thymidine; Tritium | 2003 |
A review of neurological disorders presenting at a paediatric neurology clinic and response to anticonvulsant therapy in Gambian children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Developmental Disabilities; Female; Gambia; Humans; Infant; Learning Disabilities; Male; Nervous System Diseases; Phenobarbital; Phenytoin; Psychomotor Disorders; Seizures; Treatment Outcome | 2003 |
Anticonvulsant teratogenesis 5: observer bias in a cohort study.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anticonvulsants; Boston; Cohort Studies; Face; Female; Fingers; Humans; Infant, Newborn; Observer Variation; Phenobarbital; Phenytoin; Pregnancy; Single-Blind Method; Teratogens | 2003 |
Cross-sensitivity to diphenylhydantoin sodium and to phenobarbital.
Topics: Barbiturates; Drug Eruptions; Humans; Hydantoins; Phenobarbital; Phenytoin; Sodium | 1953 |
[Experiences with comital and comital-L].
Topics: Barbiturates; Drug Combinations; Epilepsy; Hydantoins; Mephobarbital; Phenobarbital; Phenytoin | 1951 |
[Significance of the attack point of diphenylhydantoin, phenobarbital and the acylureas for our comprehension of the physiopathological mechanism of epilepsy].
Topics: Animals; Barbiturates; Behavior, Animal; Comprehension; Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin; Social Behavior; Urea | 1953 |
[Effects of phenobarbital, acylureas and diphenylhydantoin on coma during electric epileptic crisis in guinea pig. II..].
Topics: Anticonvulsants; Barbiturates; Coma; Electricity; Epilepsy; Guinea Pigs; Phenobarbital; Phenytoin; Seizures | 1953 |
Electroencephalographic studies, induced seizures, and their modification by phenobarbital, dilantin, and phenurone, in the salamanders, Triturus viridescens and Ambystoma tigrinum.
Topics: Ambystoma; Animals; Anticonvulsants; Barbiturates; Benzeneacetamides; Electroencephalography; Humans; Hydantoins; Notophthalmus viridescens; Phenobarbital; Phenytoin; Seizures; Urea; Urodela | 1954 |
A method for the simultaneous determination of phenobarbital and diphenylhydantoin in blood.
Topics: Barbiturates; Blood; Humans; Hydantoins; Phenobarbital; Phenytoin | 1956 |
Megaloblastic anaemia occurring during treatment of epilepsy with phenytoin sodium, primidone and phenobarbitone.
Topics: Anemia; Anemia, Megaloblastic; Anticonvulsants; Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone | 1957 |
The chromatographic separation and determination of diphenylhydantoin and phenobarbital.
Topics: Chromatography; Humans; Hydantoins; Phenobarbital; Phenytoin; Rare Diseases; Retinal Degeneration; Retinal Detachment | 1958 |
Diphenylhydantoin and phenobarbital in serum in patients with epilepsy.
Topics: Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin | 1958 |
[Spectrophotometric analysis of mixtures of phenobarbitone & phenytoin].
Topics: Hydantoins; Phenobarbital; Phenytoin; Spectrophotometry | 1958 |
Aspects of the pharmacology of phenytoin (dilantin) and phenobarbital relevant to their dosage in the treatment of epilepsy.
Topics: Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin | 1960 |
Differential effects of phenobarbital, pentobarbital and diphenylhydantoin on motor cortical and reticular thresholds in the rhesus monkey.
Topics: Animals; Cerebral Cortex; Humans; Hydantoins; Macaca mulatta; Mesencephalon; Pentobarbital; Phenobarbital; Phenytoin | 1961 |
Differential effects of antiepileptics on hippocampal and pallidal afterdischarges in cats.
Topics: Animals; Anticonvulsants; Cats; Epilepsy; Globus Pallidus; Hippocampus; Phenobarbital; Phenytoin | 1962 |
Convulsions in childhood.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Humans; Phenobarbital; Phenytoin; Seizures | 1963 |
[Now and then: development of drug treatment of epilepsy since A. Hauptmann].
Topics: Anticonvulsants; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Pyrrolidinones | 1962 |
The mechanism of the antagonistic action of reserpine on the anticonvulsant effect of inhibitors of carbonic anhydrase.
Topics: Acetazolamide; Anticonvulsants; Carbonic Anhydrases; Humans; Phenobarbital; Phenytoin; Reserpine | 1963 |
Increased activity of microsomal strychnine-metabolizing enzyme induced by phenobarbital and other drugs.
Topics: Glutethimide; Meprobamate; Nikethamide; Phenobarbital; Phenytoin; Primidone; Strychnine; Thiopental; Urethane | 1962 |
On the anticonvulsant activity of local anaesthetics.
Topics: Anesthesia, Local; Anesthetics, Local; Anticonvulsants; Humans; Lidocaine; Phenobarbital; Phenytoin; Tetracaine | 1962 |
Treatment of epilepsy.
Topics: Acetazolamide; Anticonvulsants; Automatism; Child; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Seizures | 1963 |
Determination of diphenylhydantoin and phenobarbital in small amounts of serum.
Topics: Humans; Phenobarbital; Phenytoin | 1963 |
[Chromatographic separation and microdetermination of phenobarbital, methylphenobarbital, butobarbital and phenytoin].
Topics: Barbiturates; Chromatography; Mephobarbital; Phenobarbital; Phenytoin | 1962 |
Effects of autonomic agents, alone and in combination with antiepileptic drugs, on electroshock seizures in rats.
Topics: Animals; Anticonvulsants; Atropine; Autonomic Agents; Electroshock; Methacholine Compounds; Neostigmine; Phenobarbital; Phenytoin; Physostigmine; Pilocarpine; Rats; Seizures | 1963 |
The influence of certain central depressants on fighting behavior of mice.
Topics: Animals; Behavior; Central Nervous System Agents; Chloral Hydrate; Chlorpromazine; Hypnotics and Sedatives; Meprobamate; Mice; Pentobarbital; Phenobarbital; Phenytoin; Reserpine | 1963 |
ANTIEPILEPTIC DRUGS.
Topics: Acetazolamide; Amphetamine; Amphetamines; Anticonvulsants; Barbiturates; Bromides; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Meprobamate; Phenobarbital; Phenytoin; Primidone; Succinimides; Toxicology | 1963 |
MEGALOBLASTIC ANEMIA ASSOCIATED WITH THE USE OF ANTICONVULSANT DRUGS. REPORT OF A CASE AND REVIEW OF THE LITERATURE.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Toxicology | 1963 |
ANTI-EPILEPTIC DRUGS AND THE FOETUS.
Topics: Barbiturates; Epilepsy; Female; Fetal Diseases; Fetus; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Toxicology | 1963 |
STIMULATORY EFFECT OF PHENOBARBITAL ON THE METABOLISM OF DIPHENYLHYDANTOIN.
Topics: Animals; Anti-Allergic Agents; Barbiturates; Dogs; Histamine H1 Antagonists; Metabolism; Mice; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Research | 1963 |
A SIMPLE METHOD TO MEASURE CENTRAL CHOLINOLYTIC ACTIVITY.
Topics: Anticonvulsants; Atropine; Carbachol; Cholinergic Antagonists; Methantheline; Mice; Pharmacology; Phenobarbital; Phenytoin; Quaternary Ammonium Compounds; Research; Seizures | 1963 |
MEGALOBLASTIC ANAEMIA ASSOCIATED WITH ANTICONVULSANT THERAPY.
Topics: Amobarbital; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Barbiturates; Epilepsy; Folic Acid; Humans; Metabolism; Phenobarbital; Phenytoin; Primidone; Toxicology; Vitamin B 12 | 1963 |
THE INFANT WITH EPILEPSY.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Birth Injuries; Classification; Diagnosis; Epilepsy; Epilepsy, Temporal Lobe; Female; Genetics, Medical; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Mephobarbital; Meprobamate; Metabolism; Myoclonus; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Seizures; Spasms, Infantile; Temporal Lobe; Toxicology; Wounds and Injuries | 1963 |
[ETIOLOGY AND THERAPY OF STATUS EPILEPTICUS].
Topics: Abortion, Septic; Anticonvulsants; Birth Injuries; Brain Injuries; Brain Neoplasms; Chloral Hydrate; Eclampsia; Electric Injuries; Encephalitis; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Humans; Intracranial Arteriosclerosis; Intracranial Embolism; Intracranial Embolism and Thrombosis; Phenobarbital; Phenytoin; Pregnancy; Psychoses, Alcoholic; Psychotic Disorders; Status Epilepticus | 1963 |
DOSAGE OF PHENYTOIN AND PHENOBARBITAL IN CHILDREN.
Topics: Blood Chemical Analysis; Child; Epilepsy; Fever; Humans; Phenobarbital; Phenytoin; Seizures | 1963 |
ANTICONVULSANT DRUGS.
Topics: Anticonvulsants; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1964 |
SUBNORMAL SERUM FOLATE AND MACROCYTOSIS ASSOCIATED WITH ANTICONVULSANT DRUG THERAPY.
Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Biological Assay; Blood Chemical Analysis; Enterococcus faecalis; Epilepsy; Folic Acid; Folic Acid Antagonists; Humans; Lactobacillus; Phenobarbital; Phenytoin; Primidone; Toxicology; Vitamin B 12 | 1964 |
[GENESIS, CLASSIFICATION AND THERAPY OF LOSS OF CONSCIOUSNESS].
Topics: Caffeine; Child; Classification; Electroencephalography; Epilepsy; Epilepsy, Absence; Humans; Oxyphenbutazone; Phenobarbital; Phenytoin; Physiology; Pyrrolidinones; Unconsciousness | 1963 |
CONVULSIONS.
Topics: Black People; Diagnosis, Differential; Epilepsy; Humans; Intellectual Disability; Phenobarbital; Phenytoin; Seizures; Tuberous Sclerosis | 1964 |
STIMULANT ACTION OF PYRIDYL DERIVATIVES OF BENZODIOXANS AND BENZODIOXEPANS.
Topics: Animals; Anticonvulsants; Atropine; Bemegride; Central Nervous System Agents; Central Nervous System Stimulants; Chlorisondamine; Chlorpromazine; Diazepam; Mephenesin; Meprobamate; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Phenytoin; Picrotoxin; Research; Seizures; Strychnine; Tranquilizing Agents | 1963 |
ANTIMALARIALS AND OTHER ANTICONVULSANT DRUGS: PREDICTIVE VALIDITY OF LABORATORY TESTS.
Topics: Animals; Anticonvulsants; Antimalarials; Chloroquine; Electric Stimulation; Hydroxychloroquine; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Phenytoin; Quinacrine; Research; Seizures | 1964 |
MEDICAL TREATMENT OF EPILEPSIES IN CHILDHOOD. A LONG-TERM SURVEY OF 801 PATIENTS.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Child; Electroencephalography; Epilepsy; Humans; Infant; Phenobarbital; Phenytoin; Primidone; Statistics as Topic | 1963 |
SOME OBSERVATIONS ON THE ELECTROGRAPHIC CORRELATES OF THE DECEREBRATE ATTACK.
Topics: Child; Coma; Decerebrate State; Electroencephalography; Epilepsy; Humans; Hypoxia, Brain; Infusions, Parenteral; Paraldehyde; Phenobarbital; Phenytoin; Prednisolone | 1964 |
PSYCHOMOTOR VARIANT TYPE OF SEIZURE DISCHARGE.
Topics: Adolescent; Anticonvulsants; Child; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Temporal Lobe | 1963 |
CONVULSIVE EQUIVALENT SYNDROME OF CHILDHOOD.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Autonomic Nervous System Diseases; Child; Chlorpromazine; Dextroamphetamine; Electroencephalography; Epilepsy; Humans; Infant; Meprobamate; Phenobarbital; Phenytoin; Statistics as Topic; Syndrome | 1964 |
[ACTION OF VARIOUS UREIDES ON K GRADIENTS OF MAMMALIAN CEREBRAL TISSUE ELECTRICALLY STIMULATED IN VITRO].
Topics: Anticonvulsants; Barbiturates; Brain; Electrophysiological Phenomena; Electrophysiology; Guinea Pigs; Hydantoins; Hypnotics and Sedatives; In Vitro Techniques; Metabolism; Pentobarbital; Pharmacology; Phenobarbital; Phenytoin; Potassium; Research; Urea | 1963 |
NEUROLOGICAL SYNDROMES OF SYSTEMIC LUPUS ERYTHEMATOSUS.
Topics: Adolescent; Anticonvulsants; Autoimmune Diseases; Blood Proteins; Cerebral Cortex; Cerebrospinal Fluid Proteins; Child; Electroencephalography; Humans; Infarction; Lupus Erythematosus, Systemic; Neurologic Manifestations; Pathology; Phenobarbital; Phenytoin; Quinacrine; Seizures; Spinal Cord; Syndrome; Toxicology | 1964 |
[TREATMENT OF EPILEPSY IN ADULTS. A BRIEF SURVEY OF THE CLINICAL PROBLEMS].
Topics: Acetazolamide; Anticonvulsants; Blood Chemical Analysis; Chloral Hydrate; Data Collection; Electroencephalography; Epilepsy; Heterocyclic Compounds; Neurosurgery; Neurosurgical Procedures; Phenobarbital; Phenytoin; Primidone; Psychology, Clinical; Social Medicine | 1964 |
CONVULSIONS IN INFANCY AND CHILDHOOD.
Topics: Anticonvulsants; Child; Electroencephalography; Encephalitis; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Phenobarbital; Phenytoin; Seizures; Spasms, Infantile; Temporal Lobe; Toxicology | 1963 |
DIPHENYLHYDANTOIN AND PHENOBARBITAL. SERUM LEVELS IN CHILDREN.
Topics: Adolescent; Blood; Child; Drug Therapy; Epilepsy; Humans; Infant; Pharmacology; Phenobarbital; Phenytoin | 1964 |
SEIZURES INDUCED BY MOVEMENT: A FORM OF REFLEX EPILEPSY.
Topics: Adolescent; Athetosis; Cerebral Angiography; Diagnosis, Differential; Electroencephalography; Epilepsy; Epilepsy, Reflex; Epilepsy, Tonic-Clonic; Humans; Neurologic Examination; Phenobarbital; Phenytoin; Primidone; Reflex; Reflex, Abnormal; Seizures; Spasm | 1964 |
[SEPARATION AND MICRODETERMINATION OF PHENOBARBITAL AND PHENYTOIN IN SERUM].
Topics: Blood Chemical Analysis; Humans; Phenobarbital; Phenytoin; Rare Diseases; Retinal Detachment | 1964 |
[OBSERVATION ON TWO CASES OF EPILEPSIA CURSIVA].
Topics: Adolescent; Atrophy; Barbiturates; Cerebral Cortex; Chlordiazepoxide; Dichlorphenamide; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Gait; Humans; Limbic System; Muscle Spasticity; Paralysis; Phenobarbital; Phenytoin; Radiography; Seizures | 1964 |
REPORT ON THE ANTI-EPILEPTIC ACTION OF TEGRETOL.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Biomedical Research; Carbamazepine; Child; Chlordiazepoxide; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Seizures; Temporal Lobe; Toxicology | 1964 |
ZARONTIN (ETHOSUXIMIDE) IN THE TREATMENT OF PETIT MAL AND RELATED DISORDERS.
Topics: Adolescent; Anticonvulsants; Biomedical Research; Child; Denmark; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Myoclonus; Oxyphenbutazone; Phenobarbital; Phenytoin; Pyrrolidinones; Seizures; Toxicology | 1964 |
[ANTI-EPILEPTIC ACTIVITY OF TRINURIDE].
Topics: Anticonvulsants; Epilepsy; Pharmacology; Phenobarbital; Phenytoin; Toxicology | 1964 |
EFFECTS OF ANTICONVULSIVE MEDICATION ON VESTIBULAR FUNCTION. AN ELECTRONYSTAGMOGRAPHIC STUDY.
Topics: Electronystagmography; Epilepsy; Humans; Nystagmus, Pathologic; Pharmacology; Phenobarbital; Phenytoin; Vestibular Function Tests | 1964 |
NOTE ON THE DETECTION OF HEXOESTROL, STILBOESTROL, DIENOESTROL AND THE P-HYDROXY METABOLITES OF PHENOBARBITONE AND PHENYTOIN IN URINE.
Topics: Chromatography; Dienestrol; Diethylstilbestrol; Estrogens; Hexestrol; Hydantoins; Phenobarbital; Phenytoin; Research; Urine | 1964 |
[INHIBITION OF ELECTROCONVULSION BY THE KAVA-PYRONES DIHYDROMETHYSTICIN AND DIHYDROKAVAIN].
Topics: Anticonvulsants; Chlorpromazine; Kava; Mice; Pharmacology; Phenobarbital; Phenytoin; Primidone; Pyrones; Rats; Research; Seizures | 1964 |
[REHABILITATION OF THE EPILEPTIC. CLINICAL EXPERIENCE WITH A POTENTIALIZED ANTICONVULSANT].
Topics: Anticonvulsants; Barbiturates; Epilepsy; Humans; Mephobarbital; Phenobarbital; Phenytoin | 1964 |
A STATE PROGRAM TO CONTROL PHENYLKETONURIA.
Topics: Adolescent; Blood; Child; Diet; Diet Therapy; Genetics, Medical; Humans; Infant; Intellectual Disability; Kansas; Mass Screening; Phenobarbital; Phenylalanine; Phenylketonurias; Phenytoin; Public Health Nursing; Seizures | 1964 |
ANTICONVULSANTS. I. DIBENZO(A,D)CYCLOHEPTADIENE-5-CARBOXAMIDE AND RELATED COMPOUNDS.
Topics: Amides; Anticonvulsants; Ataxia; Chemistry, Pharmaceutical; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Phenytoin; Primidone; Research; Seizures; Toxicology | 1964 |
EXPERIMENTAL SUBCORTICAL EPILEPTIFORM FOCUS.
Topics: Aluminum; Amygdala; Cats; Electroencephalography; Epilepsy; Hippocampus; Pharmacology; Phenobarbital; Phenytoin; Research; Reticular Formation | 1964 |
EFFECTS OF BENZODIAZEPINES ON CENTRAL NERVOUS SYSTEM OF CAT.
Topics: Anticonvulsants; Benzodiazepines; Brain; Carbamates; Carisoprodol; Cats; Cerebral Cortex; Chlordiazepoxide; Chlorpromazine; Decerebrate State; Hypothalamus; Limbic System; Pentobarbital; Pharmacology; Phenobarbital; Phenytoin; Research; Thalamus; Tranquilizing Agents | 1964 |
HINTS ON SEIZURE MANAGEMENT.
Topics: Anticonvulsants; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Phenobarbital; Phenytoin; Seizures; Toxicology | 1964 |
IATROGENIC MEGALOBLASTIC ANAEMIA WITH NEUROLOGICAL COMPLICATIONS.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Brain Diseases; Cysticercosis; Drug Therapy; Epilepsy; Folic Acid; Humans; Iatrogenic Disease; Phenobarbital; Phenytoin; Primidone; Spinal Cord; Toxicology; Vitamin B 12 | 1964 |
DIPHENYLHYDANTOIN AND PHENOBARBITAL TOXICITY. THE ROLE OF LIVER DISEASE.
Topics: Ataxia; Barbiturates; Blood Chemical Analysis; Chromatography; Drug Tolerance; Hepatitis; Hepatitis A; Humans; Liver; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Metabolism; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Spectrophotometry; Toxicology; Urine | 1964 |
[3 CASES OF TELEVISION EPILEPSY].
Topics: Child; Drug Therapy; Electroencephalography; Epilepsy; Epilepsy, Reflex; Humans; Phenobarbital; Phenytoin; Television | 1964 |
NOTE ON THE INTERACTIONS OF AMPHETAMINE WITH ANTICONVULSANT DRUGS.
Topics: Amphetamine; Amphetamines; Animals; Anticonvulsants; Electricity; Electroshock; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Phenytoin; Research; Seizures | 1964 |
BEHAVIOR DISORDERS OF CHILDREN WITH CEREBRAL DYSRHYTHMIAS; SUCCESSFUL TREATMENT OF SUBCONVULSIVE DYSRHYTHMIA WITH ANTICONVULSANTS.
Topics: Acetazolamide; Amphetamine; Amphetamines; Anticonvulsants; Child; Child Behavior Disorders; Conduct Disorder; Drug Therapy; Electroencephalography; Humans; Methylphenidate; Phenobarbital; Phenytoin; Seizures; Succinimides | 1964 |
ANESTHETIC MANAGEMENT OF THE PARTURIENT WITH INTRACRANIAL TUMOR.
Topics: Anesthesia; Anesthesia, Endotracheal; Anesthesia, Spinal; Anesthetics; Angiography; Brain Neoplasms; Cesarean Section; Cysts; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Female; Glioma; Humans; Labor, Induced; Mepivacaine; Neoplasms; Neurologic Manifestations; Oxytocics; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Procaine; Radiography; Radioisotope Teletherapy | 1964 |
[POSSIBILITIES OF COMBINED ANTICONVULSANT TREATMENT IN CHRONIC SEIZURES].
Topics: Adolescent; Anticonvulsants; Child; Drug Therapy; Epilepsy; Humans; Infant; Infant, Newborn; Phenobarbital; Phenytoin; Seizures | 1964 |
MEGALOBLASTIC ANEMIA AND NEUROLOGIC DISTURBANCES COMBINED WITH FOLIC ACID DEFICIENCY. OBSERVATIONS ON AN EPILEPTIC PATIENT TREATED WITH ANTICONVULSANTS.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Avitaminosis; Barbiturates; Brain Diseases; Central Nervous System Diseases; Cerebellar Diseases; Drug Therapy; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Neurologic Manifestations; Pathology; Phenobarbital; Phenytoin; Spinal Cord; Spinal Nerves; Toxicology; Trimethadione | 1964 |
DRUG DOSAGE. A REVIEW OF A PROBLEM IN PEDIATRICS.
Topics: Aspirin; Child; Digitoxin; Digoxin; Dosage Forms; Drug Therapy; Humans; Infant; Pediatrics; Phenobarbital; Phenytoin; Sulfadiazine; Thyroid Hormones | 1964 |
TREATMENT OF HEADACHES IN CHILDREN.
Topics: Adolescent; Child; Drug Therapy; Epilepsy; Headache; Humans; Methysergide; Migraine Disorders; Phenobarbital; Phenytoin; Toxicology | 1964 |
TEMPORAL LOBE EPILEPSY: A CLINICAL STUDY OF 47 CASES.
Topics: Adolescent; Biomedical Research; Birth Injuries; Depression; Depressive Disorder; Diagnosis, Differential; Drug Therapy; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Neurotic Disorders; Paranoid Disorders; Personality; Personality Disorders; Phenobarbital; Phenytoin; Seizures; Temporal Lobe | 1964 |
[DETERMINATION OF DIPHENYLHYDANTOIN IN THE PRESENCE OF PHENOBARBITAL IN SERUM].
Topics: Blood Chemical Analysis; Health Services; Humans; Phenobarbital; Phenytoin | 1964 |
CHILD CARE IN GENERAL PRACTICE. CONVULSIONS IN INFANCY AND CHILDHOOD. II.
Topics: Acetazolamide; Anticonvulsants; Bromides; Child; Child Care; Chloral Hydrate; Diagnosis; Drug Therapy; Electroencephalography; Epilepsy; Ethosuximide; Family Practice; General Practice; Hospitalization; Humans; Infant; Oxyphenbutazone; Paraldehyde; Phenobarbital; Phenytoin; Primidone; Prognosis; Radiography; Seizures; Toxicology | 1965 |
[THE REPRODUCTION OF AUDIOGENIC CONVULSIONS AFTER THE PRELIMINARY ADMINISTRATION OF PYRAMIDONE TO ANIMALS].
Topics: Acetazolamide; Aminopyrine; Anticonvulsants; Antipyrine; Epilepsy, Reflex; Mice; Pharmacology; Phenobarbital; Phenytoin; Primidone; Rats; Research; Seizures; Sound; Toxicology | 1964 |
PROBENECID (BENEMID) INTOXICATION WITH STATUS EPILEPTICUS.
Topics: Coma; Drug Therapy; Epilepsy; Gout; Phenobarbital; Phenytoin; Poisoning; Probenecid; Status Epilepticus; Suicide; Toxicology | 1965 |
SERUM PHENYTOIN DETERMINATIONS IN EPILEPTICS.
Topics: Anticonvulsants; Blood Chemical Analysis; Child; Drug Therapy; Electroencephalography; Epilepsy; Humans; Phenobarbital; Phenytoin; Research | 1964 |
FINDINGS SUGGESTIVE OF SYSTEMIC LUPUS ERYTHEMATOSUS IN SUBJECTS ON CHRONIC ANTICONVULSANT THERAPY.
Topics: Anticonvulsants; Barbiturates; Drug Therapy; Intellectual Disability; Lupus Erythematosus, Systemic; Phenobarbital; Phenytoin; Toxicology | 1965 |
TOLERANCE TO ANTICONVULSANT DRUGS.
Topics: Anticonvulsants; Drug Tolerance; Electroshock; Ethosuximide; Metabolism; Mice; Phenobarbital; Phenytoin; Research; Seizures; Sex; Toxicology | 1965 |
MEGALOBLASTIC ANAEMIA ASSOCIATED WITH ANTICONVULSANT DRUGS: STUDIES ON A CASE WITH FOUR RELAPSES.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Drug Therapy; Electrophoresis; Epilepsy; FIGLU Test; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Recurrence; Toxicology; Urine | 1965 |
TRIGEMINAL NEURALGIA.
Topics: Atropa belladonna; Diagnosis; Drug Therapy; Geriatrics; Neurosurgery; Neurosurgical Procedures; Niacin; Nicotinic Acids; Parasympatholytics; Phenobarbital; Phenytoin; Thiamine; Trichloroethylene; Trigeminal Neuralgia | 1965 |
APPLICATION OF DRUG METABOLISM TO DRUG TOXICITY STUDIES.
Topics: Aspirin; Blood; Chromatography; Dicumarol; Diphenhydramine; Dogs; Drug-Related Side Effects and Adverse Reactions; Glutethimide; Griseofulvin; Histamine H1 Antagonists; Liver; Meprobamate; Metabolism; Methylcholanthrene; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Piperazines; Probenecid; Rats; Research; Strychnine; Thiopental; Toxicology; Zoxazolamine | 1965 |
NEUROLOGICAL SEQUELAE FOLLOWING DILANTIN OVERDOSE IN A PATIENT AND IN EXPERIMENTAL ANIMALS.
Topics: Adolescent; Ataxia; Biomedical Research; Cats; Chlordiazepoxide; Drug Therapy; Epilepsy; Humans; Neurologic Manifestations; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Poisoning; Primidone; Rats; Toxicology | 1965 |
THE PERIODICALLY RECURRING FOCAL DISCHARGE.
Topics: Animals; Cerebrovascular Disorders; Child; Drug Therapy; Electrocardiography; Electroencephalography; Epilepsy; Haplorhini; Humans; Hyperventilation; Hypoxia, Brain; Neurophysiology; Phenobarbital; Phenytoin; Visual Perception | 1965 |
[SEPARATION AND MICRODETERMINATION OF PHENOBARBITAL AND PHENYTOIN IN HUMAN MILK].
Topics: Milk, Human; Phenobarbital; Phenytoin; Pregnancy; Rare Diseases; Toxicology | 1965 |
EFFECT OF ANTICONVULSANT DRUGS ON ELECTROCONVULSIVE SHOCK-INDUCED RETROGRADE AMNESIA.
Topics: Amnesia; Amnesia, Retrograde; Anticonvulsants; Electric Stimulation; Electroshock; Pharmacology; Phenobarbital; Phenytoin; Rats; Research | 1965 |
A study of the anticonvulsant properties of phenobarbital and dilantin.
Topics: Anticonvulsants; Barbiturates; Hydantoins; Phenobarbital; Phenytoin | 1954 |
[Study of the activity and toxicity of antiepileptic drugs (phenobarbital, diphenylhydantoin, phenylethylacetylurea and 5-ethylhexahydro-5-phenylpyrimidine-4,6-dione)].
Topics: Anticonvulsants; Barbiturates; Hydantoins; Phenobarbital; Phenytoin; Urea | 1954 |
Studies on anticonvulsant drug combinations: phenobarbital and diphenylhydantoin.
Topics: Anticonvulsants; Barbiturates; Drug Combinations; Hydantoins; Phenobarbital; Phenytoin | 1955 |
[Leukemia in an epileptic treated with gardenal and dihydan; recovery; fatal mysoline poisoning with fatty degeneration of the liver and acute epithelial nephritis].
Topics: Anticonvulsants; Barbiturates; Epilepsy; Humans; Hydantoins; Leukemia; Leukocytosis; Liver Diseases; Nephritis; Phenobarbital; Phenytoin; Poisoning; Primidone | 1955 |
Effect of lidocaine and procaine on the electroshock seizure threshold, with a comparison of the effects of phenytoin and phenobarbital.
Topics: Convulsive Therapy; Electroconvulsive Therapy; Electroshock; Humans; Hydantoins; Lidocaine; Phenobarbital; Phenytoin; Procaine; Seizures | 1960 |
Validated high performance liquid chromatographic method for simultaneous determination of phenytoin, phenobarbital and carbamazepine in human serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Humans; Indicators and Reagents; Phenobarbital; Phenytoin; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2003 |
Effects of diphenylhydantoin sodium (dilantin sodium) and phenobarbital sodium upon ectopic ventricular tachycardia in acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Barbital; Heart; Hydantoins; Myocardial Infarction; Phenobarbital; Phenytoin; Sodium; Tachycardia; Tachycardia, Ventricular; Ventricular Premature Complexes | 1950 |
Comparative results in seizure control using phenobarbital, dilantin, and mesantoin.
Topics: Barbital; Epilepsy; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Seizures | 1950 |
[Acute phenobarbital and diphenylhydantoin poisoning].
Topics: Barbiturates; Cardiovascular Agents; Humans; Hydantoins; Phenobarbital; Phenytoin | 1952 |
Cost of epilepsy in patients attending a secondary-level hospital in India.
Topics: Anticonvulsants; Carbamazepine; Efficiency, Organizational; Epilepsy; Hospital Costs; Hospitalization; Humans; India; Phenobarbital; Phenytoin; Valproic Acid | 2004 |
The effect of long-term antiepileptic treatment on serum cholesterol (TC, HDL, LDL) and triglyceride levels in adult epileptic patients on monotherapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Triglycerides; Valproic Acid | 2004 |
Anticonvulsant hypersensitivity syndrome: treatment with corticosteroids and intravenous immunoglobulin.
Topics: Adult; Anticonvulsants; Cross Reactions; Drug Hypersensitivity; Female; Glucocorticoids; Humans; Immunoglobulins, Intravenous; Methylprednisolone; Phenobarbital; Phenytoin; Prednisone; Syndrome | 2004 |
Antiepileptic drugs inhibit cell growth in the human breast cancer cell line MCF7.
Topics: Anticonvulsants; Breast Neoplasms; Cell Division; Cell Line, Tumor; Drug Screening Assays, Antitumor; Estrogens; Female; Humans; Lamotrigine; Phenobarbital; Phenytoin; Protein Binding; Receptors, Estrogen; Triazines; Valproic Acid | 2004 |
Loss of seizure control due to anticonvulsant-induced hypocalcemia.
Topics: Adult; Anticonvulsants; Humans; Hypocalcemia; Male; Phenobarbital; Phenytoin; Seizures; Vitamin D Deficiency | 2004 |
The effects of phenytoin and phenobarbital on seizures induced by imipenem/cilastatin in rats.
Topics: Animals; Anticonvulsants; Cilastatin; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Imipenem; Injections, Intraventricular; Male; Phenobarbital; Phenytoin; Prohibitins; Rats; Rats, Wistar; Seizures | 2004 |
Therapeutic doses of topiramate are not toxic to the developing rat brain.
Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Apoptosis; Brain; Dose-Response Relationship, Drug; Fructose; Neurons; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Topiramate; Valproic Acid | 2004 |
Population pharmacokinetic modeling of steady state clearance of carbamazepine and its epoxide metabolite from sparse routine clinical data.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Asian People; Body Weight; Carbamazepine; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Metabolic Clearance Rate; Methods; Models, Biological; Pharmacokinetics; Phenobarbital; Phenytoin; Regression Analysis; Valproic Acid | 2004 |
[Nonconvulsion epileptic encepholopathies and their treatment].
Topics: Adolescent; Adult; Anticonvulsants; Brain; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsy, Absence; Humans; Magnetic Resonance Imaging; Male; Phenobarbital; Phenytoin; Severity of Illness Index; Tomography, X-Ray Computed | 2004 |
Active-site characteristics of CYP2C19 and CYP2C9 probed with hydantoin and barbiturate inhibitors.
Topics: Aryl Hydrocarbon Hydroxylases; Barbiturates; Binding Sites; Computer Simulation; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Design; Enzyme Activation; Hydantoins; Mephenytoin; Mixed Function Oxygenases; Models, Chemical; Models, Molecular; Phenobarbital; Phenytoin; Protein Binding | 2004 |
Activation of serum aminotransferases by pyridoxal-5' -phosphate in epileptic patients treated with anticonvulsant drugs.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Pyridoxal Phosphate; Sensitivity and Specificity; Transaminases; Valproic Acid | 2004 |
Effects of piracetam alone and in combination with antiepileptic drugs in rodent seizure models.
Topics: Action Potentials; Animals; Anticonvulsants; Brain; Cobalt; Disease Models, Animal; Drug Combinations; Drug Synergism; Electroshock; Epilepsy; Epilepsy, Absence; Hippocampus; Male; Mice; Mice, Inbred DBA; Neuroprotective Agents; Phenobarbital; Phenytoin; Piracetam; Valproic Acid | 2004 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Hypersensitivity; Ethosuximide; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lymphatic Diseases; Phenobarbital; Phenytoin; Syndrome; Triazines; Valproic Acid | 2004 |
Toxic hepatic necrosis associated with taking dilantin, tridione and phenobarbital; report of a case.
Topics: Aged; Barbital; Hepatitis; Humans; Hydantoins; Liver; Liver Diseases; Phenobarbital; Phenytoin; Trimethadione | 1950 |
Total external ophthalmoplegia induced by phenytoin: a case report and review of literature.
Topics: Adult; Anticonvulsants; Humans; Intellectual Disability; Male; Ophthalmoplegia; Phenobarbital; Phenytoin | 2004 |
Assessment of the epilepsy treatment gap in two cities of south-east of Brazil.
Topics: Adult; Anticonvulsants; Brazil; Carbamazepine; Epilepsy; Health Services Accessibility; Health Services Needs and Demand; Humans; Phenobarbital; Phenytoin; Prevalence; Valproic Acid | 2004 |
Interactions between riluzole and conventional antiepileptic drugs -- a comparison of results obtained in the subthreshold method and isobolographic analysis.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Riluzole; Seizures; Valproic Acid | 2004 |
Isoforms of serum gamma-glutamyltransferase in epileptic patients treated with enzyme-inducing anticonvulsant drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Isoenzymes; Male; Phenobarbital; Phenytoin | 2004 |
Influence of coadministered antiepileptic drugs on serum phenobarbital concentrations in epileptic patients: quantitative analysis based on a suitable transforming factor.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Combinations; Epilepsy; Female; Humans; Infant; Isoxazoles; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Valproic Acid; Zonisamide | 2004 |
[Influence of psychotropic drugs on thrombocytes aggregation in patients with epilepsy].
Topics: Adolescent; Adult; Barbiturates; Carbamazepine; Epilepsy; Humans; In Vitro Techniques; Lamotrigine; Middle Aged; Phenobarbital; Phenytoin; Platelet Aggregation; Psychotropic Drugs; Thrombocytopenia; Triazines; Valproic Acid | 2004 |
Effect of paracetamol on uric acid determination.
Topics: Acetaminophen; Adult; Anticonvulsants; Autoanalysis; Bromides; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Drug Overdose; False Positive Reactions; Female; Humans; Oxidation-Reduction; Phenobarbital; Phenytoin; Phosphotungstic Acid; Severity of Illness Index; Substance-Related Disorders; Time Factors; Urate Oxidase; Uric Acid | 1975 |
The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cognition Disorders; Face; Facies; Female; Fingers; Follow-Up Studies; Humans; Intelligence Tests; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Toes | 2005 |
CARs and drugs: a risky combination.
Topics: Animals; Constitutive Androstane Receptor; Estradiol; Humans; Mice; Models, Chemical; Phenobarbital; Phenytoin; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Thyroid Gland; Thyroid Hormones; Transcription Factors; Xenobiotics | 2005 |
Drug-induced hypersensitivity syndrome due to anticonvulsants in a two-year-old boy.
Topics: Anticonvulsants; Child, Preschool; Diagnosis, Differential; Drug Eruptions; Humans; Male; Phenobarbital; Phenytoin; Seizures | 2004 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics.
Topics: Anticonvulsants; Carbamazepine; Causality; Epilepsy; Germany; Humans; Incidence; Inpatients; Lamotrigine; Phenobarbital; Phenytoin; Prohibitins; Registries; Reproducibility of Results; Risk Assessment; Risk Factors; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2005 |
Effect of cytochrome P450 inhibitors and anticonvulsants on the acute toxicity of acrylonitrile.
Topics: Acrylonitrile; Animals; Anticonvulsants; Carcinogens; Central Nervous System Depressants; Cyanides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Ethanol; Imidazoles; Male; Phenobarbital; Phenytoin; Proadifen; Rats; Rats, Sprague-Dawley; Seizures; Time Factors | 2005 |
Simultaneous determination of lamotrigine, phenobarbitone, carbamazepine and phenytoin in human serum by high-performance liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Reproducibility of Results; Sensitivity and Specificity; Triazines | 2005 |
Phenobarbital and phenytoin increased acetaminophen hepatotoxicity due to inhibition of UDP-glucuronosyltransferases in cultured human hepatocytes.
Topics: Acetaminophen; Cells, Cultured; Drug Interactions; Glucuronides; Glucuronosyltransferase; Glutathione; Hepatocytes; Humans; Liver; Phenobarbital; Phenytoin | 2005 |
Drug treatment of neonatal seizures by neonatologists and paediatric neurologists.
Topics: Anticonvulsants; Benzodiazepines; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Infant, Newborn, Diseases; Neurology; New South Wales; New Zealand; Phenobarbital; Phenytoin; Practice Patterns, Physicians'; Seizures; Surveys and Questionnaires; Workforce | 2005 |
Protection with estradiol in developmental models of apoptotic neurodegeneration.
Topics: Animals; Animals, Newborn; Apoptosis; Bicuculline; Blotting, Western; Brain; Caenorhabditis elegans Proteins; Cell Count; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrogen Antagonists; Extracellular Signal-Regulated MAP Kinases; GABA Antagonists; Hypoxia; Immunohistochemistry; In Situ Nick-End Labeling; Membrane Potentials; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Phenobarbital; Phenytoin; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, GABA-A; Silver Staining; Tamoxifen | 2005 |
Fit for a fracture.
Topics: Anticonvulsants; Epilepsy; Ergocalciferols; Female; Femoral Neck Fractures; Follow-Up Studies; Fractures, Spontaneous; Humans; Mental Disorders; Middle Aged; Osteoporosis; Phenobarbital; Phenytoin; Treatment Outcome; Valproic Acid; Vitamin D; Vitamin D Deficiency | 2005 |
[Rickets. A rare complication of anti-epileptic treatments. Report of two cases in children].
Topics: Anticonvulsants; Black People; Calcifediol; Child; Contraindications; Drug Monitoring; Electroencephalography; Epilepsies, Myoclonic; Ergocalciferols; Ethosuximide; Humans; Male; Phenobarbital; Phenytoin; Radiography; Rare Diseases; Rickets; Valproic Acid | 1976 |
Phenytoin stimulates chondrogenic differentiation in mouse clonal chondrogenic EC cells, ATDC5.
Topics: 3T3 Cells; Aggrecans; Animals; Anticonvulsants; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Calcification, Physiologic; Cartilage; Cell Differentiation; Cell Line, Tumor; Chondrocytes; Chondrogenesis; Chondroitin Sulfate Proteoglycans; Clone Cells; Collagen Type II; Dose-Response Relationship, Drug; Extracellular Matrix Proteins; Gene Expression; Hedgehog Proteins; Lectins, C-Type; Mice; Parathyroid Hormone-Related Protein; Patched Receptors; Patched-1 Receptor; Phenobarbital; Phenytoin; Proteins; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Trans-Activators; Valproic Acid | 2005 |
Treatment delay and the risk of prolonged status epilepticus.
Topics: Administration, Rectal; Anticonvulsants; Benzodiazepines; Child, Preschool; Clinical Protocols; Disease Progression; Early Diagnosis; Epilepsy; Female; Humans; Infusion Pumps; Male; Phenobarbital; Phenytoin; Retrospective Studies; Secondary Prevention; Status Epilepticus; Thiopental; Time Factors; Treatment Outcome | 2005 |
[Anticonvulsive pharmacotherapy may aggravate epilepsy course].
Topics: Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Fructose; Humans; Magnetic Resonance Imaging; Phenobarbital; Phenytoin; Topiramate; Valproic Acid | 2005 |
[Management of status epilepticus].
Topics: Adult; Age Factors; Aged; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Child; Diazepam; Drug Therapy, Combination; Electroencephalography; Humans; Infant; Infant, Newborn; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Prognosis; Propofol; Randomized Controlled Trials as Topic; Status Epilepticus | 2005 |
Mathematical representation of analyte's capacity factor in binary solvent mobile phases using the Jouyban-Acree model.
Topics: Algorithms; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Models, Chemical; Models, Statistical; Phenobarbital; Phenytoin; Solvents | 2005 |
2-phosphonomethyl-pentanedioic acid (glutamate carboxypeptidase II inhibitor) increases threshold for electroconvulsions and enhances the antiseizure action of valproate against maximal electroshock-induced seizures in mice.
Topics: Analysis of Variance; Animals; Anticonvulsants; Brain; Carbamazepine; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Glutamate Carboxypeptidase II; Male; Mice; Organophosphorus Compounds; Phenobarbital; Phenytoin; Psychomotor Performance; Seizures; Valproic Acid | 2006 |
When benzodiazepines fail: how effective is second line therapy for status epilepticus in children?
Topics: Anesthetics; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Diazepam; Dose-Response Relationship, Drug; Drug Therapy, Combination; Emergency Medicine; Female; Humans; Infant; Intubation, Intratracheal; Male; Medical Audit; Pediatrics; Phenobarbital; Phenytoin; Retrospective Studies; Status Epilepticus; Treatment Outcome | 2006 |
Vibrational spectra and normal coordinate analysis of diazepam, phenytoin and phenobarbitone.
Topics: Amino Acids, Aromatic; Anticonvulsants; Carbon; Diazepam; Hydrogen; Models, Biological; Nitrogen; Oxygen; Phenobarbital; Phenytoin; Porphyrins; Spectrum Analysis; Vibration | 2006 |
Correlation of retention factor of analytes in quaternary solvent mobile phases using the Jouyban-Acree model.
Topics: Algorithms; Carbamazepine; Models, Chemical; Models, Statistical; Phenobarbital; Phenytoin; Solvents | 2006 |
[Rapid analysis of antiepileptic drugs in human plasma by micellar electrokinetic capillary chromatography].
Topics: Anticonvulsants; Buffers; Carbamazepine; Chromatography, Micellar Electrokinetic Capillary; Clonazepam; Epilepsy; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Sensitivity and Specificity; Sodium Dodecyl Sulfate | 2006 |
Effect of CYP2C19 genetic polymorphism on pharmacokinetics of phenytoin and phenobarbital in Japanese epileptic patients using Non-linear Mixed Effects Model approach.
Topics: Adult; Algorithms; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; DNA; Female; Gene Frequency; Genotype; Humans; Japan; Male; Middle Aged; Mixed Function Oxygenases; Models, Statistical; Nonlinear Dynamics; Phenobarbital; Phenytoin; Polymorphism, Genetic; Population; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction.
Topics: Algorithms; Carbamazepine; Cell Line; Cell Proliferation; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Nifedipine; Phenobarbital; Phenytoin; Pioglitazone; Reproducibility of Results; Rifampin; Rosiglitazone; Sulfinpyrazone; Thiazolidinediones | 2006 |
Phenytoin induction of the cyp2c37 gene is mediated by the constitutive androstane receptor.
Topics: Animals; Constitutive Androstane Receptor; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Liver; Male; Mice; Mice, Inbred C3H; Mice, Knockout; Phenobarbital; Phenytoin; Pregnane X Receptor; Pregnenolone Carbonitrile; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Transcription Factors | 2006 |
Use of phenytoin, phenobarbital, or diazepam during pregnancy and risk of congenital abnormalities: a case-time-control study.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Case-Control Studies; Cross-Over Studies; Diazepam; Female; Humans; Hungary; Odds Ratio; Phenobarbital; Phenytoin; Population Surveillance; Pregnancy; Registries; Risk Assessment; Surveys and Questionnaires; Time Factors | 2007 |
Response to Zhou et al. Osteomalacia is a frequent complication resulting from long-term therapy with drugs such as phenytoin, carbamazepine, and phenobarbital.
Topics: Anticonvulsants; Carbamazepine; Constitutive Androstane Receptor; Gene Expression; Humans; Osteomalacia; Phenobarbital; Phenytoin; Pregnane X Receptor; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Steroid Hydroxylases; Transcription Factors; Vitamin D3 24-Hydroxylase | 2006 |
Antiepileptic TDM pattern at a tertiary care hospital in India.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; India; Pharmacology, Clinical; Pharmacy Service, Hospital; Phenobarbital; Phenytoin; Retrospective Studies | 2006 |
Treatment of status epilepticus in adults: guidelines of the Italian League against Epilepsy.
Topics: Adult; Age Factors; Anesthesia, General; Anticonvulsants; Benzodiazepines; Humans; International Agencies; Italy; Lorazepam; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Propofol; Secondary Prevention; Status Epilepticus; Thiopental; Valproic Acid | 2006 |
Conventional anticonvulsant drugs in the guinea-pig kindling model of partial seizures: effects of repeated administration.
Topics: Action Potentials; Amygdala; Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Electric Stimulation; Epilepsies, Partial; Ethosuximide; Female; Guinea Pigs; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Predictive Value of Tests; Reproducibility of Results; Species Specificity; Treatment Outcome; Valproic Acid | 2007 |
Population estimation of the effects of cytochrome P450 2C9 and 2C19 polymorphisms on phenobarbital clearance in Japanese.
Topics: Adult; Algorithms; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Asian People; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Monitoring; Epilepsy; Female; Gene Frequency; Genetics, Population; Heterozygote; Homozygote; Humans; Immunoassay; Isoxazoles; Japan; Male; Metabolic Clearance Rate; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Polymorphism, Genetic; Regression Analysis; Valproic Acid; Zonisamide | 2007 |
Resistance to phenobarbital extends to phenytoin in a rat model of temporal lobe epilepsy.
Topics: Amygdala; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Epilepsy, Temporal Lobe; Female; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Videotape Recording | 2007 |
Evaluation of therapeutic drug level monitoring of phenobarbital, phenytoin and carbamazepine in Iranian epileptic patients.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Iran; Male; Middle Aged; Phenobarbital; Phenytoin | 2007 |
Clinical utility of a continuous intravenous infusion of valproic acid in pediatric patients.
Topics: Administration, Oral; Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Drug Utilization Review; Female; Fructose; Hallucinations; Humans; Hyperammonemia; Infusions, Intravenous; Male; Medical Records; Metabolic Clearance Rate; Migraine Disorders; Phenobarbital; Phenytoin; Retrospective Studies; Seizures; Topiramate; Treatment Outcome; Valproic Acid | 2007 |
Effects of certain antiepileptics on behavioral and electromyographic seizure patterns induced by maximal electroshock in mice.
Topics: Administration, Oral; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electromyography; Electroshock; Ethosuximide; Fructose; Male; Mice; Phenobarbital; Phenytoin; Seizures; Time Factors; Topiramate | 2007 |
Chronically administered fluoxetine enhances the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Interactions; Drug Synergism; Electroshock; Fluoxetine; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Selective Serotonin Reuptake Inhibitors; Valproic Acid | 2007 |
Interactions between two enantiomers of losigamone and conventional antiepileptic drugs in the mouse maximal electroshock model--an isobolographic analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Interactions; Electroshock; Furans; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Stereoisomerism; Valproic Acid | 2007 |
Effects of lamotrigine alone and in combination with MK-801, phenobarbital, or phenytoin on cell death in the neonatal rat brain.
Topics: Animals; Animals, Newborn; Anticonvulsants; Apoptosis; Brain; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Female; Lamotrigine; Male; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Sex Factors; Thalamus; Triazines | 2007 |
The natural history and treatment of epilepsy in a murine model of tuberous sclerosis.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy; Gene Silencing; Mice; Mice, Knockout; Mice, Neurologic Mutants; Monitoring, Physiologic; Neuroglia; Phenobarbital; Phenytoin; Tuberous Sclerosis; Tumor Suppressor Proteins; Videotape Recording | 2007 |
Antiepileptic drugs affect neuronal androgen signaling via a cytochrome P450-dependent pathway.
Topics: Animals; Anticonvulsants; Cell Line, Tumor; Chloramphenicol O-Acetyltransferase; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Gene Expression; Gene Expression Regulation, Neoplastic; Immunoblotting; Isoenzymes; Ketoconazole; Membrane Proteins; Mice; Nerve Growth Factor; Neurofilament Proteins; Neurons; PC12 Cells; Phenobarbital; Phenytoin; Rats; Receptors, Androgen; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; Transfection | 2007 |
Transient hypogammaglobulinemia after antiepileptic drug hypersensitivity.
Topics: Agammaglobulinemia; Anticonvulsants; Child, Preschool; Drug Hypersensitivity; Humans; Male; Phenobarbital; Phenytoin | 2007 |
Isobolographic analysis of interactions between remacemide and conventional antiepileptic drugs in the mouse model of maximal electroshock.
Topics: Acetamides; Algorithms; Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Interactions; Electroshock; Epilepsy; Epilepsy, Tonic-Clonic; Male; Memory; Mice; Motor Skills; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2007 |
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Drug Monitoring; Ethosuximide; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature; Triazines; Valproic Acid; Zonisamide | 2007 |
Cholecalciferol enhances the anticonvulsant effect of conventional antiepileptic drugs in the mouse model of maximal electroshock.
Topics: Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Cholecalciferol; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Injections, Intraperitoneal; Male; Mental Recall; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Vitamins | 2007 |
Acute and chronic treatment with mianserin differentially affects the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model.
Topics: Analysis of Variance; Animals; Anticonvulsants; Antidepressive Agents, Second-Generation; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Electroshock; Fluorescent Antibody Technique; Male; Memory; Mianserin; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2007 |
Neonatal seizures: multicenter variability in current treatment practices.
Topics: Anticonvulsants; Consensus; Electroencephalography; Female; Humans; Infant, Newborn; Intensive Care, Neonatal; Lorazepam; Male; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Professional Practice; Retrospective Studies; Seizures; Survival Rate | 2007 |
The effect of anticonvulsant drugs on the fibrinolytic activity of tissue plasminogen activator.
Topics: Adult; Anticonvulsants; Blood Coagulation; Drug Interactions; Erythropoietin; Female; Fibrinolytic Agents; Humans; In Vitro Techniques; Levetiracetam; Male; Phenobarbital; Phenytoin; Piracetam; Recombinant Proteins; Tissue Plasminogen Activator; Valproic Acid | 2008 |
Incidence and outcome of convulsive status epilepticus in Kenyan children: a cohort study.
Topics: Adolescent; Analysis of Variance; Anticonvulsants; Child; Child, Preschool; Cohort Studies; Data Interpretation, Statistical; Female; Humans; Infant; Kenya; Malaria; Male; Meningitis, Bacterial; Phenobarbital; Phenytoin; Risk Factors; Status Epilepticus; Surveys and Questionnaires; Treatment Outcome | 2008 |
Increased P-glycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbamazepine; Cells, Cultured; Cerebral Arteries; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelial Cells; Immunosuppressive Agents; Indicators and Reagents; Microcirculation; Phenobarbital; Phenytoin; Rats; Rhodamine 123; Sodium Channel Blockers; Time; Up-Regulation; Valproic Acid; Verapamil | 2008 |
Exanthematous allergic drug reactions due to four chemically unrelated drugs.
Topics: Adult; Antibiotics, Antitubercular; Anticonvulsants; Antitubercular Agents; Erythema; Ethambutol; Exanthema; Female; Humans; Phenobarbital; Phenytoin; Pruritus; Rifampin | 2008 |
The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models.
Topics: Administration, Oral; Animals; Anticonvulsants; Disease Models, Animal; Injections, Intraperitoneal; Mice; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Seizures; Severity of Illness Index; Triazoles; Valproic Acid | 2008 |
Aromatic antiepileptic drugs and mitochondrial toxicity: effects on mitochondria isolated from rat liver.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Calcium; Calcium Signaling; Carbamazepine; Dose-Response Relationship, Drug; Male; Membrane Potential, Mitochondrial; Microsomes, Liver; Mitochondria, Liver; Mitochondrial Swelling; Oxygen Consumption; Phenobarbital; Phenytoin; Rats; Rats, Wistar | 2008 |
Effect of 21-day exposure of phenobarbital, carbamazepine and phenytoin on P-glycoprotein expression and activity in the rat brain.
Topics: Analysis of Variance; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Carbamazepine; Gene Expression; Male; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley | 2008 |
Quantification of carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbital in plasma samples by stir bar-sorptive extraction and liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Phenobarbital; Phenytoin; Sensitivity and Specificity | 2008 |
A confusing case of confusion. Acute porphyrias.
Topics: Acidosis, Lactic; Acute Disease; Anticonvulsants; Brain; Confusion; Diagnosis, Differential; Diet, Reducing; Drug Combinations; Electroencephalography; Epilepsy, Tonic-Clonic; Estrogens, Conjugated (USP); Fatal Outcome; Female; Headache; Hormone Replacement Therapy; Humans; Magnetic Resonance Imaging; Medroxyprogesterone Acetate; Middle Aged; Phenobarbital; Phenytoin; Porphyrias; Spinal Puncture; Tomography, X-Ray Computed; Valproic Acid; Vomiting; Weight Loss | 2008 |
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cysteine; Dipeptides; Drug Evaluation; Epilepsy; Female; Folic Acid; Humans; Hyperhomocysteinemia; Liver; Male; Methionine; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Riboflavin; Valproic Acid; Vitamin B Deficiency | 2008 |
Resistance to antiepileptic drugs and expression of P-glycoprotein in two rat models of status epilepticus.
Topics: Amygdala; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; Diazepam; Disease Models, Animal; Drug Resistance; Electric Stimulation; Endothelium, Vascular; Female; Gene Expression Regulation; Genes, MDR; Hippocampus; Phenobarbital; Phenytoin; Pilocarpine; Quinolines; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2008 |
Involvement of oxidative stress in the hepatotoxicity induced by aromatic antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Cardiolipins; Liver; Male; Malondialdehyde; Microsomes, Liver; Mitochondria, Liver; Oxidation-Reduction; Oxidative Stress; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Sulfhydryl Compounds; Toxicity Tests | 2008 |
Anticonvulsant actions of trimethadione-phenobarbital and trimethadione-diphenylhydantoin combinations.
Topics: Anticonvulsants; Humans; Phenobarbital; Phenytoin; Seizures; Trimethadione | 1948 |
Audit of treatment of convulsive status epilepticus.
Topics: Anticonvulsants; Child; Diazepam; Humans; Midazolam; Paraldehyde; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Status Epilepticus | 2008 |
Drug treatment of epilepsy in the century of the ILAE: the first 50 years, 1909-1958.
Topics: Advertising; Anticonvulsants; Bromides; Epilepsy; Herbal Medicine; History, 18th Century; History, 19th Century; History, 20th Century; Humans; Neurology; Phenobarbital; Phenytoin; Textbooks as Topic | 2009 |
Benign familial neonatal convulsions: novel mutation in a newborn.
Topics: Amino Acid Sequence; Anticonvulsants; Brain; Diagnosis, Differential; DNA Mutational Analysis; Echocardiography; Electroencephalography; Epilepsy, Benign Neonatal; Humans; Infant, Newborn; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Magnetic Resonance Imaging; Molecular Sequence Data; Mutation, Missense; Phenobarbital; Phenytoin; Polymerase Chain Reaction; Seizures; Sequence Homology | 2009 |
N-(anilinomethyl)-p-isopropoxyphenylsuccinimide potentiates the anticonvulsant action of phenobarbital and valproate in the mouse maximal electroshock-induced seizure model.
Topics: Aniline Compounds; Animals; Anticonvulsants; Brain; Carbamazepine; Dose-Response Relationship, Drug; Drug Synergism; Male; Memory; Mice; Models, Animal; Motor Activity; Muscle Strength; Phenobarbital; Phenytoin; Seizures; Succinimides; Valproic Acid | 2009 |
The combined action of phenobarbitone and epanutin.
Topics: Anticonvulsants; Barbital; Barbiturates; Humans; Hydantoins; Phenobarbital; Phenytoin | 1947 |
Comparative anticonvulsant actions of isopropyl alcohol, diphenylhydantoin, phenobarbital and tridione.
Topics: 1-Propanol; 2-Propanol; Anticonvulsants; Humans; Phenobarbital; Phenytoin; Propanols; Seizures; Trimethadione | 1947 |
In vitro concentration dependent transport of phenytoin and phenobarbital, but not ethosuximide, by human P-glycoprotein.
Topics: Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Blood-Brain Barrier; Calcium Channel Blockers; Cell Line; Dose-Response Relationship, Drug; Ethosuximide; Humans; In Vitro Techniques; Phenobarbital; Phenytoin; Rhodamine 123; Verapamil | 2010 |
Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients.
Topics: Adolescent; Adult; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbamazepine; Epilepsy; Female; Genotype; Humans; Male; Pharmacogenetics; Phenobarbital; Phenytoin; Valproic Acid; Young Adult | 2010 |
Effects of three N-(carboxyanilinomethyl) derivatives of p-isopropoxyphenylsuccinimide on the anticonvulsant action of carbamazepine, phenobarbital, phenytoin and valproate in the mouse maximal electroshock-induced seizure model.
Topics: Aniline Compounds; Animals; Anticonvulsants; Behavior, Animal; Brain; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Male; Memory; Mice; Motor Activity; Muscle Strength; Muscle, Skeletal; Phenobarbital; Phenytoin; Seizures; Succinimides; Valproic Acid | 2010 |
Management of neonatal seizures.
Topics: Anticonvulsants; Benzodiazepines; Electroencephalography; Epilepsies, Myoclonic; Humans; Hypocalcemia; Infant, Newborn; Phenobarbital; Phenytoin; Prognosis; Seizures | 2010 |
Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Child; China; Clonazepam; Cyclohexanecarboxylic Acids; Exanthema; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Medicine, Chinese Traditional; Middle Aged; Phenobarbital; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Triazines; Valproic Acid; Young Adult | 2010 |
Effects of continued administration of phenobarbital and diphenylhydantoin.
Topics: Barbital; Humans; Hydantoins; Phenobarbital; Phenytoin | 1946 |
An organotypic hippocampal slice culture model of excitotoxic injury induced spontaneous recurrent epileptiform discharges.
Topics: Action Potentials; Animals; Anticonvulsants; Cell Survival; Epilepsy; Ethosuximide; Glutamic Acid; Hippocampus; Nerve Net; Neurons; Neurotoxins; Organ Culture Techniques; Patch-Clamp Techniques; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Stroke | 2011 |
Status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Child; Clinical Protocols; Fructose; GABA Modulators; Humans; Ketamine; Levetiracetam; Midazolam; Pentobarbital; Phenobarbital; Phenytoin; Piracetam; Propofol; Status Epilepticus; Thiopental; Topiramate; Valproic Acid | 2011 |
Synthetic cannabinoid WIN 55,212-2 mesylate enhances the protective action of four classical antiepileptic drugs against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzoxazines; Cannabinoid Receptor Agonists; Carbamazepine; Drug Synergism; Electroshock; Male; Memory, Long-Term; Mice; Morpholines; Muscle Strength; Naphthalenes; Phenobarbital; Phenytoin; Psychomotor Performance; Seizures; Valproic Acid | 2011 |
Suicidal risk and suicide attempts in people treated with antiepileptic drugs for epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Comorbidity; Depressive Disorder; Electroencephalography; Epilepsy; Female; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Phenobarbital; Phenytoin; Prohibitins; Risk Factors; Suicidal Ideation; Suicide; Suicide, Attempted; Triazines; Young Adult | 2011 |
One-way multiplexed immunoassay strategy for simultaneous determination of multi-analytes by microchip electrophoresis.
Topics: Antibodies, Immobilized; Carbamazepine; Electrophoresis, Microchip; Glass; Humans; Immunoassay; Phenobarbital; Phenytoin; Sodium Dodecyl Sulfate; Theophylline | 2011 |
Thyroid status in a large cohort of patients with mental retardation: the TOP-R (Thyroid Origin of Psychomotor Retardation) study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Cohort Studies; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Hypothyroidism; Intellectual Disability; Lamotrigine; Linear Models; Male; Middle Aged; Netherlands; Phenobarbital; Phenytoin; Prevalence; Thyroid Gland; Thyrotropin; Thyroxine; Triazines; Triiodothyronine; Valproic Acid | 2011 |
Pharmacokinetic and pharmacodynamic interactions of valproate, phenytoin, phenobarbitone and carbamazepine with curcumin in experimental models of epilepsy in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Curcumin; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Epilepsy; Male; Maze Learning; Phenobarbital; Phenytoin; Random Allocation; Rats; Rats, Wistar; Valproic Acid | 2011 |
Development and validation of a reference measurement procedure for certification of phenytoin, phenobarbital, lamotrigine, and topiramate in human serum using isotope-dilution liquid chromatography/tandem mass spectrometry.
Topics: Anticonvulsants; Chromatography, Reverse-Phase; Fructose; Humans; Indicator Dilution Techniques; Lamotrigine; Phenobarbital; Phenytoin; Prohibitins; Reference Standards; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Topiramate; Triazines | 2011 |
[Epilepsy in elderly].
Topics: Aged; Aged, 80 and over; Aging; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Female; Fructose; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Topiramate; Triazines; Valproic Acid | 2011 |
Novel micro-extraction by packed sorbent procedure for the liquid chromatographic analysis of antiepileptic drugs in human plasma and urine.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Humans; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Prohibitins; Sensitivity and Specificity; Solid Phase Extraction; Spectrophotometry, Ultraviolet | 2012 |
Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report.
Topics: Anticonvulsants; Denture, Complete; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Gingiva; Gingival Hyperplasia; Gingival Overgrowth; Gingivectomy; Humans; Jaw, Edentulous, Partially; Middle Aged; Phenobarbital; Phenytoin; Tooth Extraction; Tooth Mobility; Valproic Acid | 2012 |
Concentrations of stiripentol in children and adults with epilepsy: the influence of dose, age, and comedication.
Topics: Adult; Age Factors; Anticonvulsants; Body Weight; Child; Child, Preschool; Dioxolanes; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Regression Analysis; Retrospective Studies; Sex Factors; Young Adult | 2012 |
Sequential interaction of phenytoin and phenobarbital with fluorouracil.
Topics: Drug Interactions; Fluorouracil; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 2012 |
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)?
Topics: Anticonvulsants; Carbamazepine; Drug Discovery; Epilepsy; Ethosuximide; History, 20th Century; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Structure-Activity Relationship; Succinimides; Valproic Acid | 2012 |
Risk factors for hyperammonemia in pediatric patients with epilepsy.
Topics: Acetazolamide; Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy; Female; Fructose; Humans; Hyperammonemia; Infant; Isoxazoles; Male; Phenobarbital; Phenytoin; Retrospective Studies; Risk Factors; Sex Factors; Topiramate; Valproic Acid; Zonisamide | 2013 |
Drug rash with eosinophilia and systemic symptoms syndrome associated with use of phenytoin, divalproex sodium, and phenobarbital.
Topics: Adult; Drug Eruptions; Drug Substitution; Eosinophilia; Female; Humans; Phenobarbital; Phenytoin; Valproic Acid | 2013 |
First HPLC-UV method for rapid and simultaneous quantification of phenobarbital, primidone, phenytoin, carbamazepine, carbamazepine-10,11-epoxide, 10,11-trans-dihydroxy-10,11-dihydrocarbamazepine, lamotrigine, oxcarbazepine and licarbazepine in human plas
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Drug Stability; Humans; Lamotrigine; Limit of Detection; Linear Models; Phenobarbital; Phenytoin; Reproducibility of Results; Triazines | 2013 |
Phenobarbital-induced severe cutaneous adverse drug reactions are associated with CYP2C19*2 in Thai children.
Topics: Adolescent; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Child; Child, Preschool; Cytochrome P-450 CYP2C19; DNA Mutational Analysis; Drug Hypersensitivity; Female; Genotype; HLA-B15 Antigen; Humans; Infant; Infant, Newborn; Male; Phenobarbital; Phenytoin; Polymorphism, Genetic; Skin; Thailand | 2013 |
Status epilepticus in a child secondary to ingestion of skin-lightening cream.
Topics: Anticonvulsants; Ataxia; Eating; Emergencies; Humans; Hydroquinones; Infant; Intubation, Intratracheal; Lorazepam; Male; Phenobarbital; Phenytoin; Physical Therapy Modalities; Seizures; Skin Lightening Preparations; Status Epilepticus | 2013 |
Anticonvulsants for neonates: high time we were seized of the matter.
Topics: Anticonvulsants; Female; Humans; Infant, Newborn, Diseases; Male; Phenobarbital; Phenytoin; Seizures | 2013 |
Anti-epileptic drugs inhibit viability of synoviocytes in vitro.
Topics: Animals; Anticonvulsants; Arthritis, Rheumatoid; Carbamazepine; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Histone Deacetylase Inhibitors; Humans; Phenobarbital; Phenytoin; Rabbits; Synovial Membrane; Valproic Acid | 2013 |
Effect of CYP3A5 genotypes on the pharmacokinetics of carbamazepine when used as monotherapy or co-administered with phenytoin, phenobarbital or valproic acid in Thai patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Asian People; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Female; Genotype; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid; Young Adult | 2013 |
Antiepileptic drug utilization in Bangladesh: experience from Dhaka Medical College Hospital.
Topics: Adolescent; Adult; Anticonvulsants; Bangladesh; Carbamazepine; Child; Drug Combinations; Epilepsies, Partial; Epilepsy, Generalized; Female; Follow-Up Studies; Fructose; Hospitals, Teaching; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prohibitins; Retrospective Studies; Seizures; Topiramate; Treatment Outcome; Valproic Acid | 2013 |
Neonatal seizures: continued debate on phenobarbitone versus phenytoin.
Topics: Anticonvulsants; Female; Humans; Infant, Newborn, Diseases; Male; Phenobarbital; Phenytoin; Seizures | 2013 |
Reply: To PMID 23502660.
Topics: Anticonvulsants; Female; Humans; Infant, Newborn, Diseases; Male; Phenobarbital; Phenytoin; Seizures | 2013 |
The ratio of 6β-hydroxycortisol to cortisol in urine as a measure of cytochrome P450 3A activity in postmortem cases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Carbamazepine; Child; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Female; Forensic Toxicology; Humans; Hydrocortisone; Liver Cirrhosis; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Young Adult | 2014 |
Myoclonic seizures in a preterm baby: is this a presentation of venlafaxine withdrawal?
Topics: Antidepressive Agents; Cyclohexanols; Electroencephalography; Female; Humans; Infant, Newborn; Infant, Premature; Magnetic Resonance Imaging; Maternal Exposure; Phenobarbital; Phenytoin; Pregnancy; Seizures; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride | 2014 |
Correlation between trough plasma dabigatran concentrations and estimates of glomerular filtration rate based on creatinine and cystatin C.
Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B; Benzimidazoles; Carboxylic Ester Hydrolases; Creatinine; Cystatin C; Dabigatran; Female; Genotype; Glomerular Filtration Rate; Humans; Linear Models; Male; Middle Aged; Phenobarbital; Phenytoin; Pyridines | 2014 |
Reboxetine and its influence on the action of classical antiepileptic drugs in the mouse maximal electroshock model.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Epilepsy; Male; Memory, Long-Term; Mice; Morpholines; Motor Activity; Phenobarbital; Phenytoin; Reboxetine; Valproic Acid | 2014 |
Interaction of famotidine, an H2 histamine receptor antagonist, with conventional antiepileptic drugs in mice.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Drug Interactions; Electroshock; Famotidine; Histamine H2 Antagonists; Male; Memory, Long-Term; Mice; Phenobarbital; Phenytoin; Psychomotor Performance; Valproic Acid | 2014 |
[Epilepsy in the child and in the adult. Part 1. Epilepsy in the child].
Topics: Anticonvulsants; Benzodiazepines; Child; Electroencephalography; Epilepsy; Follow-Up Studies; Humans; Patient Education as Topic; Phenobarbital; Phenytoin; Treatment Outcome | 2014 |
Interaction of injectable neurotropic drugs with the red cell membrane.
Topics: Central Nervous System Agents; Chlorpromazine; Citalopram; Clomipramine; Clonazepam; Diazepam; Erythrocytes; Humans; Injections; Levetiracetam; Microscopy, Electron, Scanning; Neurotransmitter Agents; Phenobarbital; Phenytoin; Piracetam; Valproic Acid | 2014 |
Liquid chromatographic assay based on microextraction by packed sorbent for therapeutic drug monitoring of carbamazepine, lamotrigine, oxcarbazepine, phenobarbital, phenytoin and the active metabolites carbamazepine-10,11-epoxide and licarbazepine.
Topics: Anticonvulsants; Carbamazepine; Chemical Fractionation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dibenzazepines; Drug Monitoring; Epoxy Compounds; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Quality Control; Reproducibility of Results; Triazines | 2014 |
Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Brain; Carbamazepine; Cells, Cultured; Central Nervous System Depressants; Child, Preschool; Cytochrome P-450 CYP2E1; Disease Models, Animal; Endothelial Cells; Ethanol; Female; Humans; Infant; Male; Mice; Mice, Inbred C57BL; Middle Aged; Neurons; Phenobarbital; Phenytoin; Status Epilepticus | 2014 |
Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Resistance; Electrodes, Implanted; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hippocampus; Kainic Acid; Levetiracetam; Mice; Phenobarbital; Phenytoin; Piracetam; Seizures; Valproic Acid | 2015 |
Modafinil and its metabolites enhance the anticonvulsant action of classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzhydryl Compounds; Brain; Carbamazepine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Electroshock; Hand Strength; Male; Mice; Modafinil; Phenobarbital; Phenytoin; Psychomotor Performance; Seizures; Sulfones; Valproic Acid | 2015 |
Independent predictors of delay in emergence from general anesthesia.
Topics: Adult; Ambulatory Care; Anesthesia, Dental; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Anticonvulsants; Benzodiazepines; Clobazam; Clonazepam; Cohort Studies; Delayed Emergence from Anesthesia; Dental Care for Disabled; Female; Follow-Up Studies; Humans; Intellectual Disability; Male; Methyl Ethers; Phenobarbital; Phenytoin; Piperidines; Propofol; Remifentanil; Retrospective Studies; Risk Factors; Sevoflurane; Valproic Acid | 2015 |
Simultaneous extraction and quantification of lamotrigine, phenobarbital, and phenytoin in human plasma and urine samples using solidified floating organic drop microextraction and high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Lamotrigine; Limit of Detection; Liquid Phase Microextraction; Organic Chemicals; Osmolar Concentration; Phenobarbital; Phenytoin; Reproducibility of Results; Solid Phase Microextraction; Solvents; Temperature; Triazines | 2015 |
Effect of xanthotoxin (8-methoxypsoralen) on the anticonvulsant activity of classical antiepileptic drugs against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Male; Methoxsalen; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2015 |
Pediatric Herpes Simplex Virus Encephalitis Complicated by N-Methyl-D-aspartate Receptor Antibody Encephalitis.
Topics: Acyclovir; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Antiviral Agents; Autoantibodies; Clonidine; Diazepam; Encephalitis, Herpes Simplex; Encephalomalacia; Female; Fever; Humans; Immunocompromised Host; Immunosuppression Therapy; Infant; Leukoencephalopathies; Movement Disorders; Neurological Rehabilitation; Pakistan; Paresis; Phenobarbital; Phenytoin; Plasmapheresis; Receptors, N-Methyl-D-Aspartate; Seizures; Trihexyphenidyl; United Kingdom; Valproic Acid | 2015 |
Effects of CYP3A4/5 and ABCB1 genetic polymorphisms on carbamazepine metabolism and transport in Chinese patients with epilepsy treated with carbamazepine in monotherapy and bitherapy.
Topics: Adolescent; Adult; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; Carbamazepine; Child; China; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Epilepsy; Female; Genotype; Humans; Male; Middle Aged; Pharmacogenetics; Phenobarbital; Phenytoin; Polymorphism, Single Nucleotide; Valproic Acid; Young Adult | 2015 |
Concentration of antiepileptic drugs in persons with epilepsy: a comparative study in serum and saliva.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prohibitins; Saliva; Young Adult | 2016 |
Synaptic vesicle protein2A decreases in amygdaloid-kindling pharmcoresistant epileptic rats.
Topics: Amygdala; Animals; Anticonvulsants; Disease Models, Animal; Drug Resistance; Electric Stimulation; Epilepsy; Gene Expression Regulation; Hippocampus; Kindling, Neurologic; Male; Membrane Glycoproteins; Nerve Tissue Proteins; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Synaptic Transmission; Synaptic Vesicles | 2015 |
Application of Micropatterned Cocultured Hepatocytes to Evaluate the Inductive Potential and Degradation Rate of Major Xenobiotic Metabolizing Enzymes.
Topics: Biological Transport; Cells, Cultured; Coculture Techniques; Cytochrome P-450 Enzyme System; Half-Life; Hepatocytes; Humans; Phenobarbital; Phenytoin; Rifampin; RNA, Messenger; Xenobiotics | 2016 |
Mexiletine and its Interactions with Classical Antiepileptic Drugs: An Isobolographic Analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Interactions; Electroshock; Male; Memory, Long-Term; Mexiletine; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Tissue Distribution; Valproic Acid | 2016 |
Propafenone enhances the anticonvulsant action of classical antiepileptic drugs in the mouse maximal electroshock model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Male; Mice; Phenobarbital; Phenytoin; Propafenone; Valproic Acid | 2016 |
Factors influencing topiramate clearance in adult patients with epilepsy: A population pharmacokinetic analysis.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fructose; Humans; Male; Middle Aged; Models, Biological; Oxcarbazepine; Phenobarbital; Phenytoin; Topiramate; Valproic Acid; Young Adult | 2016 |
The effects of cimetidine chronic treatment on conventional antiepileptic drugs in mice.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Cimetidine; Drug Interactions; Electroshock; Male; Memory, Long-Term; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2016 |
Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model.
Topics: Administration, Oral; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Induction; Gastrointestinal Tract; Hepatocytes; Humans; Liver; Models, Biological; Phenobarbital; Phenytoin; Rifampin; RNA, Messenger | 2016 |
The effects of co-medications on lamotrigine clearance in Japanese children with epilepsy.
Topics: Adolescent; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Infant, Newborn; Isoxazoles; Japan; Lamotrigine; Levetiracetam; Male; Phenobarbital; Phenytoin; Piracetam; Triazines; Valproic Acid; Young Adult; Zonisamide | 2016 |
Development, validation and clinical application of an online-SPE-LC-HRMS/MS for simultaneous quantification of phenobarbital, phenytoin, carbamazepine, and its active metabolite carbamazepine 10,11-epoxide.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2016 |
Changing antiepileptic drug use for seizures in US neonatal intensive care units from 2005 to 2014.
Topics: Anticonvulsants; Child; Drug Utilization; Female; Humans; Infant; Infant, Newborn; Intensive Care Units, Neonatal; Levetiracetam; Male; Phenobarbital; Phenytoin; Piracetam; Retrospective Studies; Seizures; Texas | 2017 |
New model of pharmacoresistant seizures induced by 3-mercaptopropionic acid in mice.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Drug Resistant Epilepsy; Hippocampus; Immunohistochemistry; Male; Mice; Phenobarbital; Phenytoin; Random Allocation; Seizures | 2017 |
Preliminary study of the association between the elimination parameters of phenytoin and phenobarbital.
Topics: Adult; Anticonvulsants; Drug Monitoring; Epilepsy; Female; Humans; Linear Models; Male; Middle Aged; Phenobarbital; Phenytoin; Retrospective Studies; Young Adult | 2017 |
Treatment outcomes after the introduction of a new seizure management protocol.
Topics: Adult; Anticonvulsants; Clinical Protocols; Drug-Related Side Effects and Adverse Reactions; Emergency Service, Hospital; Female; Humans; Levetiracetam; Male; Middle Aged; Phenobarbital; Phenytoin; Piracetam; Retrospective Studies; Status Epilepticus; Treatment Outcome; Valproic Acid | 2018 |
A survey of antiepileptic drug responses identifies drugs with potential efficacy for seizure control in Wolf-Hirschhorn syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clobazam; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Quality of Life; Seizures; Topiramate; Wolf-Hirschhorn Syndrome; Young Adult | 2018 |
Comparison of CYP3A4-Inducing Capacity of Enzyme-Inducing Antiepileptic Drugs Using 4β-Hydroxycholesterol as Biomarker.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Biomarkers; Carbamazepine; Cytochrome P-450 CYP3A Inducers; Drug Monitoring; Enzyme Induction; Female; Humans; Hydroxycholesterols; Levetiracetam; Male; Middle Aged; Phenobarbital; Phenytoin; Retrospective Studies; Young Adult | 2018 |
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Logistic Models; Male; Oxcarbazepine; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Topiramate; Valproic Acid; Young Adult | 2018 |
Combination of phenobarbital with phenytoin and pregabalin produces synergy in the mouse tonic-clonic seizure model: An isobolographic analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Electric Stimulation; Male; Mice; Muscle Strength; Phenobarbital; Phenytoin; Pregabalin; Seizures | 2018 |
Frequency of drug combinations between enzyme-inducing first-generation antiepileptic drugs and inducible drugs in patients with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme Inducers; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Italy; Male; Middle Aged; Phenobarbital; Phenytoin | 2018 |
Cunaniol-elicited seizures: Behavior characterization and electroencephalographic analyses.
Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Disease Models, Animal; Electroencephalography; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Seizures | 2018 |
Drug-drug interactions among drugs prescribed for nontuberculous mycobacterial infection and epilepsy: A case report.
Topics: Aged; Anti-Bacterial Agents; Anticonvulsants; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Humans; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Phenobarbital; Phenytoin | 2019 |
Influence of dronedarone (a class III antiarrhythmic drug) on the anticonvulsant potency of four classical antiepileptic drugs in the tonic-clonic seizure model in mice.
Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Behavior, Animal; Brain; Carbamazepine; Disease Models, Animal; Dronedarone; Drug Interactions; Male; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2019 |
New derivative of 1,2,4-triazole-3-thione (TP427) potentiates the anticonvulsant action of valproate, but not that of carbamazepine, phenytoin or phenobarbital in the mouse tonic-clonic seizure model.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Male; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2019 |
Clinical profiles associated with serum perampanel concentrations in children with refractory epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dizziness; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Absence; Female; Humans; Infant; Male; Nitriles; Phenobarbital; Phenytoin; Pyridones; Retrospective Studies; Treatment Outcome | 2019 |
Influence of etiology on treatment choices for neonatal seizures: A survey among pediatric neurologists.
Topics: Anticonvulsants; Child, Preschool; Electroencephalography; Epilepsy; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Italy; Male; Neurologists; Pediatricians; Phenobarbital; Phenytoin; Seizures; Surveys and Questionnaires | 2019 |
FGF12p.Gly112Ser variant as a cause of phenytoin/phenobarbital responsive epilepsy.
Topics: Alleles; Amino Acid Substitution; Anticonvulsants; Child, Preschool; Electroencephalography; Epilepsy; Exome Sequencing; Fibroblast Growth Factors; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Magnetic Resonance Imaging; Male; Mutation; Phenobarbital; Phenytoin | 2019 |
Antiepileptic drug-induced psychosis associated with MTHFR C677T: a case report.
Topics: Adolescent; Anticonvulsants; Avitaminosis; Epilepsy; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Phenobarbital; Phenytoin; Polymorphism, Genetic; Psychoses, Substance-Induced; Young Adult | 2019 |
Hippocampal low-frequency stimulation improves cognitive function in pharmacoresistant epileptic rats.
Topics: Animals; Anticonvulsants; Cognition; Disease Models, Animal; Electric Stimulation; Epilepsy; Hippocampus; Kindling, Neurologic; Male; Memory; Phenobarbital; Phenytoin; Rats, Sprague-Dawley; Seizures | 2020 |
The number and kind of antiepileptics affect propofol dose requirement for anesthesia: observational study.
Topics: Anticonvulsants; Humans; Phenobarbital; Phenytoin; Propofol; Valproic Acid | 2020 |
Drug therapy problems and treatment satisfaction among ambulatory patients with epilepsy in a specialized hospital in Ethiopia.
Topics: Adolescent; Adult; Ambulatory Care Facilities; Anticonvulsants; Cross-Sectional Studies; Drug Interactions; Epilepsy; Ethiopia; Female; Humans; Male; Medication Adherence; Middle Aged; Personal Satisfaction; Phenobarbital; Phenytoin; Prospective Studies; Surveys and Questionnaires; Young Adult | 2020 |
Influence of dose and antiepileptic comedication on brivaracetam serum concentrations in patients with epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dibenzazepines; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Pyrrolidinones; Retrospective Studies; Young Adult | 2020 |
Analytical validation of a quantitative method for therapeutic drug monitoring on the Alinity
Topics: Amikacin; Automation, Laboratory; Colorimetry; Drug Monitoring; Gentamicins; Humans; Immunoassay; Nephelometry and Turbidimetry; Phenobarbital; Phenytoin; Reproducibility of Results; Theophylline; Valproic Acid; Vancomycin | 2020 |
Effects of antiepileptic drugs on electroencephalography (EEG): Insights and applicability.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid; Young Adult | 2020 |
Efficacy of Fosphenytoin as First-Line Antiseizure Medication for Neonatal Seizures Compared to Phenobarbital.
Topics: Anticonvulsants; Child, Preschool; Cohort Studies; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Phenobarbital; Phenytoin; Retrospective Studies; Seizures; Treatment Outcome | 2021 |
First-line medication dosing in pediatric refractory status epilepticus.
Topics: Adolescent; Age Factors; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Resistant Epilepsy; Female; Guideline Adherence; Humans; Infant; Levetiracetam; Male; Multivariate Analysis; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Proportional Hazards Models; Retrospective Studies; Sex Factors; Status Epilepticus; Time-to-Treatment | 2020 |
Therapeutic Monitoring of Lacosamide in Japanese Patients With Epilepsy: Clinical Response, Tolerability, and Optimal Therapeutic Range.
Topics: Adult; Anticonvulsants; Asian People; Carbamazepine; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Lacosamide; Male; Phenobarbital; Phenytoin; Sodium Channel Blockers | 2020 |
Pharmacokinetics, tolerability, and clinical effectiveness of perampanel in Japanese patients with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Japan; Male; Phenobarbital; Phenytoin; Seizures; Treatment Outcome | 2020 |
Anticonvulsant Effectiveness and Neurotoxicity Profile of 4-butyl-5-[(4-chloro-2-methylphenoxy)methyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione (TPL-16) in Mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Male; Mice; Muscle Strength; Phenobarbital; Phenytoin; Rotarod Performance Test; Seizures; Thiones; Triazoles; Valproic Acid | 2021 |
When Coadministration Cannot Be Avoided: Real World Experience of Direct Acting Antivirals for the Treatment of Hepatitis C Virus Infection in Patients on First Generation Anticonvulsants.
Topics: Anticonvulsants; Antiviral Agents; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Humans; Phenobarbital; Phenytoin; Retrospective Studies | 2022 |
Acute and chronic treatment with moclobemide, a reversible MAO-inhibitor, potentiates the antielectroshock activity of conventional antiepileptic drugs in mice.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Epilepsy; Female; Male; Memory, Long-Term; Mice; Moclobemide; Monoamine Oxidase Inhibitors; Motor Activity; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2021 |
The Impact of Strong Inducers on Direct Oral Anticoagulant Levels.
Topics: Administration, Oral; Aged; Anticoagulants; Carbamazepine; Cytochrome P-450 Enzyme Inducers; Drug Interactions; Drug Monitoring; Female; Humans; Male; Phenobarbital; Phenytoin; Retrospective Studies; Rifampin | 2021 |
pH-induced homogeneous liquid-liquid microextraction method based on new switchable deep eutectic solvent for the extraction of three antiepileptic drugs from breast milk.
Topics: Anticonvulsants; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Lamotrigine; Liquid Phase Microextraction; Milk, Human; Phenobarbital; Phenytoin; Solvents | 2021 |
Chronic limbic epilepsy models for therapy discovery: Protocols to improve efficiency.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Epilepsy; Levetiracetam; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Rats; Seizures | 2021 |
Association between anti-seizure medication and outcomes in infants.
Topics: Anticonvulsants; Humans; Infant; Infant, Newborn; Levetiracetam; Phenobarbital; Phenytoin; Retrospective Studies | 2022 |
Neuropsychological effects in children exposed to anticonvulsant monotherapy during gestation: Phenobarbital, carbamazepine, and phenytoin.
Topics: Anticonvulsants; Carbamazepine; Child; Female; Humans; Intelligence Tests; Phenobarbital; Phenytoin; Pregnancy | 2022 |
Assessment of porphyrogenicity of drugs and chemicals in selected hepatic cell culture models through a fluorescence-based screening assay.
Topics: Cell Culture Techniques; Heme; Hepatocytes; Humans; Liver; Norgestrel; Phenobarbital; Phenytoin; Porphobilinogen Synthase; Porphyrias, Hepatic; Valproic Acid | 2022 |
Status Epilepticus Australasian Registry for Children: A pilot prospective, observational, cohort study of paediatric status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Cohort Studies; Female; Humans; Levetiracetam; Male; Midazolam; Phenobarbital; Phenytoin; Pilot Projects; Prospective Studies; Registries; Seizures; Status Epilepticus | 2022 |
A novel three-dimensional printed device with conductive elements for electromembrane extraction combined with high-performance liquid chromatography and ultraviolet detector.
Topics: Chromatography, High Pressure Liquid; Electric Conductivity; Electrochemical Techniques; Electrodes; Membranes, Artificial; Phenobarbital; Phenytoin; Printing, Three-Dimensional | 2022 |
Trimetazidine, an Anti-Ischemic Drug, Reduces the Antielectroshock Effects of Certain First-Generation Antiepileptic Drugs.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Electroshock; Epilepsy; Mice; Phenobarbital; Phenytoin; Trimetazidine; Valproic Acid | 2022 |
Caffeine intoxication: Behavioral and electrocorticographic patterns in Wistar rats.
Topics: Animals; Anticonvulsants; Caffeine; Diazepam; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Seizures | 2022 |
Case of bullous pemphigoid refractory to corticosteroids by antiepileptic drug-induced CYP3A4.
Topics: Adrenal Cortex Hormones; Anticonvulsants; Cytochrome P-450 CYP3A; Humans; Pemphigoid, Bullous; Phenobarbital; Phenytoin | 2023 |
Ranolazine Interacts Antagonistically with Some Classical Antiepileptic Drugs-An Isobolographic Analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Epilepsy; Mice; Phenobarbital; Phenytoin; Ranolazine; Seizures | 2022 |
Interaction of Varenicline with Classic Antiseizure Medications in the Mouse Maximal Electroshock-Induced Seizure Model.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Humans; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Varenicline | 2023 |
A real-life pilot study of the clinical application of pharmacogenomics testing on saliva in epilepsy.
Topics: Anticonvulsants; Clobazam; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Epilepsy; Humans; Pharmacogenetics; Phenobarbital; Phenytoin; Pilot Projects; Saliva | 2023 |
HLA alleles and antiseizure medication-induced cutaneous reactions in Brazil: A case-control study.
Topics: Alleles; Brazil; Carbamazepine; Case-Control Studies; HLA-A Antigens; HLA-B Antigens; Humans; Oxcarbazepine; Phenobarbital; Phenytoin | 2023 |
Anticonvulsant effects of isopimpinellin and its interactions with classic antiseizure medications and borneol in the mouse tonic-clonic seizure model: an isobolographic transformation.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electroshock; Humans; Mice; Phenobarbital; Phenytoin; Seizures | 2023 |
Urgent first-step screening method for ketamine, phenobarbital, zopiclone, zolpidem, phenytoin and thiopental in adulterated soft drink.
Topics: Caffeine; Carbonated Beverages; Female; Humans; Ketamine; Phenobarbital; Phenytoin; Reproducibility of Results; Thiopental; Zolpidem | 2023 |
Trends and Differences in Status Epilepticus Treatment of Children and Adults Over 10 Years: A Comparative Study of Medical Records (2012-2021) from a University Hospital in Germany.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Benzodiazepines; Child; Female; Hospitals, University; Humans; Lacosamide; Levetiracetam; Male; Medical Records; Midazolam; Middle Aged; Phenobarbital; Phenytoin; Propofol; Status Epilepticus; Valproic Acid | 2023 |